preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
437 |
4. Check minimum number of eventsNone |
437 |
5. Include endpointsNone |
437 |
6. Filter based on genotype QC (FinnGen only) |
437 |
Control definitions (FinnGen only)
- Control exclude
- O15_OEDEM_PROTUR_HYPERT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O10-O16
- Name in latin
- Hypertensio graviditatis non specificata
Similar endpoints
↥List of similar endpoints to Unspecified maternal hypertension based on the number of shared cases.
Similar with more cases:
- Pregnancy hypertension
- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2797 | 2797 | - |
Only index persons | 2780 | 2780 | - |
Unadjusted period prevalence (%) | |||
Whole population | 0.08 | 0.08 | - |
Only index persons | 0.10 | 0.10 | - |
Median age at first event (years) | |||
Whole population | - | 30.63 | - |
Only index persons | - | 30.63 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 437 | 437 | - |
Unadjusted period prevalence (%) | 0.15 | 0.15 | - |
Median age at first event (years) | 30.97 | 30.97 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 382
- Matched controls
- 3818
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint O15_MATERN_HYPERT_UNS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_MATERN_HYPERT_UNS.N-year risk | Females | Males |
---|---|---|
1 | No data | No data |
5 | No data | No data |
10 | No data | No data |
15 | No data | No data |
20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_MATERN_HYPERT_UNS – Unspecified maternal hypertension
GWS hits: -