preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditionsNone |
293218 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
464 |
4. Check minimum number of eventsNone |
464 |
5. Include endpointsNone |
464 |
6. Filter based on genotype QC (FinnGen only) |
451 |
Control definitions (FinnGen only)
- Control exclude
- O15_OEDEM_PROTUR_HYPERT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O10-O16
- Name in latin
- Hypertensio graviditatis non specificata
Similar endpoints
↥List of similar endpoints to
Unspecified maternal hypertension
based on the number of shared cases.
Similar with more cases:
- Pregnancy hypertension
- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2797 | 2797 | - |
| Only index persons | 2780 | 2780 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.10 | 0.10 | - |
| Median age at first event (years) | |||
| Whole population | - | 30.63 | - |
| Only index persons | - | 30.63 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 451 | 451 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 31.13 | 31.13 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 464
- Matched controls
- 4640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O16
ICD-10 Finland
Unspecified maternal hypertension
+∞
307.7
425
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1681.3
219.3
196
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
78.4
73
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
65.2
61
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
5.4
61.0
158
403
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.7
56.6
187
578
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
469.6
44.0
43
*
I10
ICD-10 Finland
Essential (primary) hypertension
3.5
37.3
193
780
C09AA02
ATC
enalapril; systemic
6.3
36.6
67
121
6429A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Unspecified hypertension complicating pregnancy, childbirth, or the puerperium[HYPERTENSIO GRAVIDARUM NUD,ENNEN SYNNYTYSTÄ]
+∞
35.9
34
*
C07AG01
ATC
labetalol; systemic
46.0
34.7
42
10
O14.1
ICD-10 Finland
Severe pre-eclampsia
+∞
32.7
31
*
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
9.8
32.6
39
43
205
Kela drug reimbursment
Chronic hypertension
6.1
30.9
58
107
C08CA05
ATC
nifedipine; systemic
7.7
30.2
44
62
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.0
27.7
313
1888
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.2
26.2
137
541
SPAT1324
SPAT
Screening procedure
2.8
25.6
213
1081
W84
ICPC
Pregnancy high risk
4.0
22.0
69
194
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.8
21.3
147
667
C09CA01
ATC
losartan; oral
3.4
21.0
87
295
C08CA01
ATC
amlodipine; oral
3.0
18.8
99
386
ZXD05
NOMESCO Finland
Urgent procedure
2.3
17.5
205
1172
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.0
17.1
51
138
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
4.3
16.1
43
107
SPAT1210
SPAT
Application of cast or individual aid
5.3
16.0
33
66
C07AB02
ATC
metoprolol; systemic
3.3
15.4
65
221
E66.9
ICD-10 Finland
Obesity, unspecified
4.2
14.7
41
105
OAA41, ,
SPAT
4.4
14.5
38
93
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.8
14.3
46
131
OAA11, ,
SPAT
2.9
14.2
76
296
LX2A3, ,
SPAT
4.2
13.2
36
91
OAA10, ,
SPAT
3.2
12.8
53
178
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.6
12.4
80
343
SPAT1249
SPAT
Treatment-related counselling outside office
2.0
11.6
216
1417
C07AB07
ATC
bisoprolol; oral
2.1
11.5
137
764
SPAT1373
SPAT
Combined screening in early pregnancy
4.0
10.6
30
78
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.4
10.5
39
122
C09CA06
ATC
candesartan; oral
2.2
10.5
105
545
C09DA01
ATC
losartan and diuretics; oral
3.9
10.3
31
84
WX234
NOMESCO Finland
Paracervical blockade
3.0
10.1
46
163
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.6
9.8
60
249
E66.01
ICD-10 Finland
Obesity due to excess calories
2.4
9.5
75
351
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.0
9.5
124
710
6423A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, ENNEN SYNNYTYSTÄ]
+∞
9.4
9
*
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
+∞
9.4
9
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.6
9.1
56
234
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
8.9
109
607
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.0
8.9
21
31
OAB30, ,
SPAT
5.0
8.9
19
39
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.3
8.6
73
352
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.6
8.5
28
81
OAA12, ,
SPAT
2.6
8.5
49
198
SPAT1263
SPAT
Sampling
1.8
8.4
204
1415
O10.9
ICD-10 Finland
Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
8.4
8
*
SPAT1379
SPAT
Health check-up of pregnant person
1.9
8.3
130
787
K85
ICPC
Elevated blood pressure
2.8
8.3
44
170
O60
ICD-10 Finland
Preterm labour and delivery
3.1
8.3
35
119
OAB47, ,
SPAT
2.6
8.2
50
207
SPAT1301
SPAT
No procedures
1.9
8.2
136
840
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
7.9
161
1055
C09CA07
ATC
telmisartan; oral
4.2
7.9
21
52
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.9
7.7
37
135
ZXH09, ,
SPAT
3.7
7.7
24
67
W78
ICPC
Pregnancy
1.8
7.5
172
1165
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
3.2
7.5
30
99
SPAT1196
SPAT
Monitoring of normal pregnancy
2.0
7.4
85
460
O12.1
ICD-10 Finland
Gestational proteinuria
81.3
7.4
8
*
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.7
7.4
40
156
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.7
7.3
268
2060
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.8
7.3
36
134
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
5.8
7.1
19
34
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.1
7.1
70
359
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.9
7.0
34
125
C08CA13
ATC
lercanidipine; oral
2.9
7.0
32
114
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.3
6.7
51
234
SPAT1260
SPAT
Consultation of another employee
2.0
6.6
74
397
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
6.3
6.5
16
26
SPAT1312
SPAT
General health counselling
1.7
6.5
159
1089
J01CA04
ATC
amoxicillin; systemic
2.1
6.4
412
3655
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.7
6.4
17
31
O12.0
ICD-10 Finland
Gestational oedema
18.3
6.3
9
5
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.1
6.3
65
339
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.8
6.3
19
52
SPAT1193
SPAT
Pap smear
1.8
6.2
101
613
R03.0
ICD-10 Finland
Elevated blood-pressure reading, without diagnosis of hypertension
2.9
6.2
28
99
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
3.3
6.1
22
68
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.6
6.0
34
136
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
144
322
6.03
64.80
1.6
1.4
—
—
—
0
0
128
307
5.38
52.37
5.0
4.0
—
—
—
0
0
177
800
2.96
26.71
4.5
3.0
1.01
1.02
kg/l
—
8
96
120
518
2.78
18.86
3.5
3.7
15.65
6.45
mg/mmol
1.08
91
318
184
1003
2.38
17.52
4.5
3.1
0.00
0.01
estimate
1.08
32
381
41
96
4.59
16.53
5.1
9.5
93.79
94.80
%
0.41
41
96
107
483
2.58
15.08
1.7
1.4
—
—
—
0
0
133
682
2.33
14.08
2.3
1.8
307.41
4269.12
umol/l
2.27
128
634
280
1943
2.11
13.53
4.2
2.9
0.00
0.00
estimate
0.50
33
394
278
1936
2.09
13.16
5.1
4.0
0.00
0.00
estimate
0.50
34
383
130
697
2.20
12.15
3.2
2.8
7.98
7.89
mmol/l
0.07
125
621
62
240
2.83
11.67
2.2
2.2
80.56
86.91
ml/min/173m2
0.67
16
87
275
1960
1.99
11.59
4.3
2.9
0.00
0.01
estimate
0.78
34
375
228
1525
1.97
11.55
3.9
2.8
—
—
—
0
0
171
1038
2.03
11.40
3.3
2.7
—
—
—
0
0
129
725
2.08
10.49
1.6
1.5
—
—
—
0
0
58
232
2.71
10.24
5.7
5.7
105.64
105.19
mmol/l
0.42
58
232
51
193
2.85
9.99
6.1
9.6
0.21
0.94
mmol/l
0.59
33
131
25
69
3.77
8.12
2.1
1.8
0.73
0.67
%
0.45
25
69
25
73
3.56
7.50
2.1
2.0
1.72
1.41
%
0.46
25
73
25
75
3.47
7.21
1.1
1.2
—
—
—
0
0
137
896
1.75
6.61
1.8
1.6
1.12
0.64
mg/l
2.21
106
655
414
3683
2.15
6.29
9.8
8.2
3.91
3.88
mmol/l
1.68
406
3575
232
1766
1.63
6.18
4.7
3.9
6.38
6.15
mmol/l
0.98
201
1570
412
3675
2.08
5.95
9.9
8.2
139.24
139.51
mmol/l
2.09
404
3580
90
538
1.83
5.81
2.7
2.2
14313.31
4104.93
u/l
1.06
32
215
57
296
2.06
5.55
2.2
1.7
—
—
—
0
0
64
347
1.98
5.54
1.7
1.9
27.50
29.07
s
2.46
64
338
162
1165
1.60
5.24
3.7
4.1
35.62
37.43
g/l
3.02
155
1106
72
415
1.87
5.19
1.4
1.4
—
—
—
0
0
72
416
1.86
5.15
1.4
1.4
—
—
—
0
0
72
417
1.86
5.11
1.4
1.4
—
—
—
0
0
49
249
2.08
5.06
1.5
1.5
—
—
—
0
0
139
1881
0.63
4.95
4.3
5.1
28.18
29.80
%
1.21
132
1786
71
415
1.84
4.90
1.4
1.4
—
—
—
0
0
75
447
1.81
4.86
2.7
2.2
1.75
0.95
e6/l
0.70
50
233
393
3521
1.76
4.62
3.3
2.8
1.25
1.16
mmol/l
2.35
384
3376
140
1869
0.64
4.57
4.0
4.9
58.76
56.65
%
1.42
133
1770
73
443
1.77
4.45
1.4
1.5
—
—
—
0
0
37
178
2.17
4.40
1.2
1.1
—
—
—
0
0
128
912
1.56
4.17
2.8
2.4
90.11
15.89
ng/l
0.43
46
314
379
3391
1.64
4.13
4.8
4.4
14.56
14.15
pmol/l
3.28
364
3231
414
3812
1.80
3.81
5.4
5.0
1.66
1.98
mu/l
0.54
399
3671
30
142
2.19
3.74
3.1
2.1
4.10
4.42
umol/l
0.13
20
101
402
3682
1.69
3.63
3.5
3.1
1.47
1.55
mmol/l
3.92
393
3551
8
13
6.24
3.51
3.4
1.9
—
—
—
0
0
402
3692
1.66
3.47
3.6
3.1
4.84
4.81
mmol/l
0.24
393
3569
32
161
2.06
3.43
3.3
6.9
5.32
6.50
mmol/l
0.75
32
155
8
14
5.79
3.35
1.5
1.3
—
—
—
0
0
386
3528
1.56
3.20
3.6
3.1
5.52
5.50
mmol/l
0.21
368
3358
403
3721
1.63
3.19
3.9
3.2
2.99
2.89
mmol/l
1.79
394
3580
171
1352
1.42
3.19
1.8
1.6
—
—
—
0
0
32
167
1.98
3.13
5.8
5.5
1.18
1.26
mmol/l
0.22
32
161
424
3971
1.79
3.13
10.4
9.2
16.57
17.55
mg/l
0.34
333
2975
180
1447
1.40
3.02
1.7
1.5
—
—
—
0
0
12
37
3.30
2.95
1.4
1.2
—
—
—
0
0
226
1894
1.38
2.92
2.4
2.4
—
—
—
0
0
11
32
3.50
2.91
1.5
1.5
239.73
487.89
pmol/l
1.36
11
27
107
789
1.46
2.87
2.8
2.5
0.25
0.28
e6/l
0.11
83
587
53
335
1.66
2.81
1.8
1.5
—
—
—
0
0
50
314
1.66
2.72
1.4
1.5
—
—
—
0
0
29
155
1.93
2.68
1.7
2.1
66.26
68.01
g/l
0.77
29
144
89
646
1.47
2.58
2.2
1.7
—
—
—
0
0
128
994
1.40
2.57
2.8
2.4
55.15
57.43
u/l
0.23
118
936
109
826
1.42
2.51
2.6
1.8
—
—
—
0
0
13
52
2.54
2.38
1.1
1.6
—
—
—
0
0
29
163
1.83
2.33
2.6
2.7
5.51
5.81
kpa
1.09
29
158
29
163
1.83
2.33
2.5
2.7
1.15
1.67
mmol/l
0.26
22
131
19
95
2.04
2.13
1.2
1.5
3.47
3.57
mmol/l
0.22
19
89
15
68
2.25
2.13
1.5
1.4
28.71
31.71
nmol/l
0.19
15
53
7
22
3.21
1.88
1.4
1.1
—
—
—
0
0
0
53
0.00
1.88
0.0
1.4
—
—
—
0
0
338
3616
0.76
1.84
11.2
10.9
14.86
14.03
%
1.82
333
3564
108
859
1.34
1.83
1.7
1.8
—
—
—
0
0
5
12
4.20
1.83
1.0
1.1
—
—
—
0
0
7
23
3.07
1.80
1.6
1.7
76.49
108.01
nmol/24h
—
7
23
8
29
2.79
1.80
1.3
1.3
—
—
—
0
0
24
139
1.77
1.79
1.0
1.2
—
—
—
0
0
36
234
1.58
1.77
1.3
1.6
—
—
—
0
0
6
18
3.36
1.75
4.8
3.3
966.33
446.00
u/ml
—
6
18
27
164
1.69
1.72
2.2
1.5
—
—
—
0
0
16
83
1.96
1.66
1.1
1.1
—
—
—
0
0
336
3117
1.28
1.61
4.2
3.6
37.26
36.80
mmol/mol
0.47
326
2986
187
1630
1.25
1.52
5.0
4.9
8.74
9.27
umol/l
0.47
173
1543
5
126
0.39
1.52
1.0
1.3
—
2.34
—
0
14
5
129
0.38
1.51
1.0
1.3
—
16.92
—
0
29
139
1173
1.26
1.49
4.6
4.5
1.19
1.22
mmol/l
4.19
134
1088
13
66
2.00
1.44
2.2
3.0
1.40
1.24
mg/l
0.44
13
61
5
16
3.15
1.44
1.0
1.6
—
—
—
0
0
14
249
0.55
1.42
3.1
2.5
—
—
—
0
0
39
273
1.47
1.40
3.5
5.1
1.02
1.04
mmol/l
0.25
39
254
301
2785
1.23
1.33
3.3
3.5
9.21
8.60
mm/h
0.56
284
2644
15
83
1.83
1.33
1.0
1.1
—
—
—
0
0
6
24
2.52
1.30
1.0
1.2
3122.50
1726.58
miu/ml
—
6
24
456
4483
2.00
1.27
16.5
13.6
39.84
39.78
%
0.11
441
4312
5
116
0.42
1.27
3.0
1.9
—
—
—
0
0
457
4495
2.11
1.22
16.7
13.8
133.21
133.21
g/l
0.00
457
4459
43
572
0.73
1.20
1.4
1.5
—
—
—
0
0
108
909
1.25
1.18
2.2
1.9
2.99
2.53
mg/l
1.56
103
784
28
400
0.68
1.17
2.6
1.7
—
—
—
0
0
99
1171
0.80
1.14
1.8
1.7
99.17
99.13
pmol/l
0.00
60
679
5
22
2.29
1.03
1.0
1.1
—
—
—
0
0
23
156
1.50
1.00
2.1
2.2
2.45
5.78
iu/l
—
10
68
23
158
1.48
0.95
1.0
1.1
3.89
3.01
u/ml
—
8
76
27
192
1.43
0.95
1.0
1.3
0.36
2.55
u/ml
—
5
12
67
805
0.80
0.89
1.5
1.6
1.41
1.32
mmol/l
0.47
62
735
15
96
1.58
0.85
4.7
2.7
9.92
9.32
mg/l
0.16
15
86
6
31
1.95
0.84
1.2
1.6
—
—
—
0
0
12
187
0.63
0.80
1.6
1.8
—
—
—
0
0
0
25
0.00
0.79
0.0
1.9
—
—
—
0
0
151
1361
1.16
0.78
4.5
5.2
1.20
1.22
mmol/l
2.20
142
1175
13
83
1.58
0.75
1.2
1.2
—
—
—
0
0
21
150
1.42
0.74
1.2
1.3
—
—
—
0
0
14
93
1.52
0.70
1.2
1.2
8.38
5.94
u/ml
—
8
34
30
231
1.32
0.69
1.3
1.5
—
—
—
0
0
18
127
1.43
0.69
1.1
1.2
—
—
—
0
0
27
205
1.34
0.69
1.2
1.6
—
—
—
0
0
7
43
1.64
0.67
1.0
1.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.2
—
—
—
0
0
12
78
1.55
0.66
1.2
1.2
100.43
219.97
u/ml
—
7
54
12
176
0.67
0.63
1.5
2.7
1.21
1.23
mmol/l
0.92
12
149
104
1161
0.87
0.63
1.2
1.3
0.63
1.39
u/ml
1.22
36
315
5
30
1.67
0.61
1.0
2.1
1.80
1.79
mmol/l
—
5
30
9
140
0.64
0.61
1.1
1.3
—
23.93
—
0
8
13
88
1.49
0.61
1.5
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
10
64
1.57
0.59
1.3
1.3
—
—
—
0
0
121
1097
1.14
0.58
1.9
2.1
—
—
—
0
0
136
1243
1.13
0.57
2.0
2.2
—
—
—
0
0
8
55
1.46
0.56
1.7
1.6
6.13
7.23
mmol/l
—
8
55
8
123
0.64
0.55
1.8
2.8
0.17
0.11
e6/l
—
8
117
36
295
1.24
0.55
1.5
1.3
241.12
239.43
miu/ml
0.01
20
162
45
379
1.21
0.53
3.8
2.5
273.00
600.75
ng/l
0.84
39
303
9
62
1.46
0.53
2.4
2.1
—
—
—
0
0
230
2178
1.11
0.52
6.1
7.8
4.37
3.98
e9/l
1.99
206
1928
6
41
1.47
0.50
1.5
1.2
—
—
—
0
0
17
127
1.35
0.50
1.1
1.2
—
—
—
0
0
26
321
0.80
0.48
1.0
1.0
—
—
—
0
0
7
50
1.41
0.45
1.0
1.2
—
—
—
0
0
12
87
1.39
0.42
1.0
1.1
—
12.25
—
0
8
63
560
1.14
0.42
1.3
1.5
1.25
1.30
%
0.34
58
516
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
100.33
—
0
15
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
18
227
0.78
0.41
2.2
2.3
0.23
0.24
g/l
0.12
18
217
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
14
107
1.32
0.37
4.5
5.7
23.57
24.40
mmol/l
0.54
14
107
8
116
0.68
0.37
1.1
1.3
—
27.06
—
0
10
5
37
1.36
0.37
1.0
1.3
—
—
—
0
0
5
37
1.36
0.37
1.0
1.3
—
—
—
0
0
86
788
1.11
0.36
1.3
1.3
7.11
12.18
u/ml
0.39
50
339
6
42
1.43
0.35
1.2
1.7
3.18
9.96
u/ml
—
6
42
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
42
369
1.15
0.34
1.5
1.7
—
—
—
0
0
17
209
0.81
0.33
2.4
2.2
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
7
99
0.70
0.31
1.6
1.6
—
—
—
0
0
12
152
0.78
0.30
1.4
1.9
1.33
1.18
g/l
0.93
12
142
20
168
1.20
0.27
1.7
1.3
—
—
—
0
0
266
2585
1.07
0.27
6.0
6.0
71.50
71.29
u/l
0.04
251
2451
11
86
1.29
0.26
1.9
1.8
—
—
—
0
0
54
495
1.10
0.24
1.1
1.2
157.65
163.60
iu/ml
0.05
29
209
377
3714
1.08
0.24
4.1
4.1
—
—
—
0
0
86
809
1.08
0.22
1.3
1.3
20.05
20.85
iu/ml
0.04
24
272
5
40
1.25
0.22
1.0
1.1
160.60
212.84
mg/l
—
5
32
247
2406
1.06
0.22
3.3
2.9
56.70
56.52
ug/l
0.01
242
2294
13
107
1.22
0.22
2.6
2.5
42.31
74.99
ng/l
1.57
13
96
0
11
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
2.12
—
0
13
0
13
0.00
0.21
0.0
1.2
—
102.38
—
0
13
0
13
0.00
0.21
0.0
1.2
—
37.55
—
0
13
6
48
1.25
0.20
1.0
1.1
—
—
—
0
0
15
127
1.19
0.20
1.3
1.5
—
0.01
—
0
19
6
50
1.20
0.20
1.0
1.1
—
—
—
0
0
12
143
0.83
0.19
1.4
1.9
0.25
0.24
g/l
0.20
12
134
34
309
1.11
0.19
1.4
1.5
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
1.9
3.6
—
191.40
—
0
5
5
67
0.74
0.17
1.0
1.4
—
—
—
0
0
8
68
1.18
0.16
1.3
1.3
0.95
1.82
nmol/l
—
8
59
17
193
0.88
0.16
2.3
3.2
64.74
64.88
ng/l
0.01
17
180
11
94
1.17
0.13
2.7
2.0
12.95
13.19
%
0.42
11
94
16
144
1.12
0.10
1.3
2.3
—
—
—
0
0
15
166
0.90
0.10
1.5
1.7
—
—
—
0
0
15
136
1.11
0.08
1.0
1.1
0.37
1.60
u/ml
—
7
61
6
58
1.03
0.08
1.2
1.2
—
—
—
0
0
5
61
0.82
0.08
1.4
1.3
—
—
—
0
0
5
64
0.78
0.08
1.4
1.3
—
—
—
0
0
5
65
0.77
0.08
1.0
1.1
—
7419.96
—
0
17
12
108
1.11
0.07
1.3
1.2
—
—
—
0
0
104
1018
1.03
0.07
7.5
5.4
1.04
1.03
inr
0.05
21
364
47
455
1.04
0.05
3.0
2.5
921.44
528.56
ng/l
0.17
25
191
42
433
0.97
0.04
3.1
2.4
9.05
5.39
e6/l
0.42
20
219
29
299
0.97
0.02
1.2
1.3
—
20.84
—
0
14
287
2879
0.99
0.01
2.4
2.6
35.66
30.54
u/l
0.83
275
2791
353
3529
1.00
0.00
6.2
7.1
94.52
95.30
ml/min/173m2
0.32
273
2837
5
50
1.00
0.00
1.4
1.2
—
—
—
0
0
5
50
1.00
0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
3.38
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
0.88
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
93
0.97
-0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
44.21
—
0
8
0
7
0.00
-0.00
0.0
3.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
1.17
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.8
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_MATERN_HYPERT_UNS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_MATERN_HYPERT_UNS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_MATERN_HYPERT_UNS – Unspecified maternal hypertension
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data