Unspecified maternal hypertension

O15_MATERN_HYPERT_UNS

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O16
  • Hospital discharge: ICD-9 6429
  • Cause of death: ICD-10 O16
  • Cause of death: ICD-9 6429

2 out of 7 registries used, show all original rules.

437

4. Check minimum number of events

None

437

5. Include endpoints

None

437

6. Filter based on genotype QC (FinnGen only)

437

Control definitions (FinnGen only)

Control exclude
O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O10-O16
Name in latin
Hypertensio graviditatis non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2797 2797 -
Only index persons 2780 2780 -
Unadjusted period prevalence (%)
Whole population 0.08 0.08 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 30.63 -
Only index persons - 30.63 -

-FinnGen-

Key figures

All Female Male
Number of individuals 437 437 -
Unadjusted period prevalence (%) 0.15 0.15 -
Median age at first event (years) 30.97 30.97 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
382
Matched controls
3818
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O16
ICD-10 Finland
Unspecified maternal hypertension
+∞
323.0
346
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1260.6
169.5
153
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
62.2
58
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
60.0
56
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
5.5
44.0
160
440
WX306
NOMESCO Finland
Lumbar epidural anesthesy
5.6
40.1
138
349
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
+∞
33.8
32
*
6429A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Unspecified hypertension complicating pregnancy, childbirth, or the puerperium[HYPERTENSIO GRAVIDARUM NUD,ENNEN SYNNYTYSTÄ]
+∞
32.8
31
*
C07AG01
ATC
labetalol; systemic
56.5
30.9
36
7
O14.1
ICD-10 Finland
Severe pre-eclampsia
+∞
28.5
27
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.0
23.4
250
1466
I10
ICD-10 Finland
Essential (primary) hypertension
3.4
21.7
127
486
SPAT1324
SPAT
Screening procedure
2.8
20.3
184
941
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.3
18.2
109
414
C09CA01
ATC
losartan; oral
4.0
16.1
70
205
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.8
15.8
121
538
205
Kela drug reimbursment
Chronic hypertension
5.4
14.7
45
92
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
8.3
14.2
31
40
C08CA05
ATC
nifedipine; systemic
6.4
14.0
37
63
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.6
12.9
45
107
W84
ICPC
Pregnancy high risk
4.0
12.5
51
141
C09AA02
ATC
enalapril; systemic
4.7
12.2
42
98
SPAT1210
SPAT
Application of cast or individual aid
6.5
12.1
31
51
SPAT1357
SPAT
Monitoring of problem during pregnancy
4.2
11.1
43
113
OAA41
SPAT
NA
11.0
10.4
19
18
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.9
10.1
65
253
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
4.1
10.1
39
103
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.4
9.5
90
433
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
+∞
9.4
9
*
C07AB07
ATC
bisoprolol; oral
2.2
9.0
103
543
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
8.7
179
1197
E66.9
ICD-10 Finland
Obesity, unspecified
4.4
8.6
30
72
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
13.2
8.4
14
11
C07AB02
ATC
metoprolol; systemic
2.9
7.9
47
174
WX234
NOMESCO Finland
Paracervical blockade
3.5
7.9
36
110
SPAT1316
SPAT
Extensive health check-up of children and adolescents
3.5
7.7
35
107
O12.0
ICD-10 Finland
Gestational oedema
81.6
7.4
8
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.5
7.3
18
29
6423A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, ENNEN SYNNYTYSTÄ]
+∞
7.3
7
*
O10.9
ICD-10 Finland
Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
7.3
7
*
O12.1
ICD-10 Finland
Gestational proteinuria
+∞
7.3
7
*
K85
ICPC
Elevated blood pressure
3.5
7.2
32
97
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.6
7.1
54
230
C08CA01
ATC
amlodipine; oral
2.5
7.0
54
233
-
ICD-10 Finland
NA
7.8
7.0
15
20
SPAT1379
SPAT
Health check-up of pregnant person
2.0
6.9
98
560
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.0
6.8
92
516
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.4
6.5
58
269
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.6
6.4
27
79
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.1
6.2
79
428
SPAT1301
SPAT
No procedures
1.9
6.1
111
690
SPAT1263
SPAT
Sampling
1.7
6.1
169
1200
SPAT1312
SPAT
General health counselling
1.8
6.1
132
870
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
6.1
115
724
O99.80
ICD-10 Finland
The fear of childbirth
2.3
6.1
54
252
SPAT1380
SPAT
Postpartum check-up
2.0
6.0
85
484

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
84
207
4.79
32.46
3.3
3.0
—
—
—
0
0
180
767
3.29
31.32
4.4
3.0
—
—
—
0
0
167
748
3.00
25.75
4.6
3.1
1.0
1.0
kg/l
—
8
89
38
59
6.96
23.85
3.2
3.6
—
—
—
0
0
177
937
2.49
18.43
4.6
3.1
0.0
0.0
estimate
1.08
31
356
40
94
4.58
16.08
4.2
10.4
—
—
—
0
0
39
93
4.51
15.39
5.0
9.7
93.6
94.9
%
0.51
39
93
225
1414
2.22
14.87
4.0
2.7
—
—
—
0
0
110
510
2.55
14.74
3.6
3.9
16.5
6.8
mg/mmol
1.04
84
311
106
492
2.52
14.12
3.4
3.2
80.8
286.5
mg/l
0.57
85
295
127
656
2.32
13.25
2.3
1.9
308.5
3931.2
umol/l
2.03
122
603
258
1810
2.04
11.72
4.3
2.9
0.0
0.0
estimate
0.00
30
343
286
2101
2.05
11.20
2.9
2.5
—
—
—
0
0
256
1812
2.00
11.10
5.1
4.0
0.0
0.0
estimate
0.50
33
358
88
420
2.37
10.81
1.8
1.4
—
—
—
0
0
119
662
2.10
9.98
3.3
2.9
8.3
7.8
mmol/l
0.54
111
582
253
1838
1.89
9.57
4.3
2.9
0.0
0.0
estimate
0.78
33
350
49
186
2.84
9.57
6.1
10.0
0.5
1.0
mmol/l
0.35
30
129
77
387
2.20
8.26
1.8
1.5
—
—
—
0
0
29
88
3.46
8.22
2.6
3.2
0.1
0.4
g/l
0.88
18
34
105
599
1.99
8.04
2.1
2.1
—
—
—
0
0
63
326
2.09
6.22
1.7
2.0
27.6
29.1
s
2.37
63
318
393
3494
2.24
6.22
9.9
8.4
3.9
3.9
mmol/l
1.95
385
3389
22
69
3.30
5.95
2.3
2.0
1.7
1.4
%
0.38
22
69
128
846
1.73
5.94
1.8
1.7
1.1
0.6
mg/l
1.98
101
618
391
3486
2.16
5.87
10.0
8.4
139.3
139.5
mmol/l
1.68
383
3394
29
112
2.70
5.51
8.4
7.2
—
—
—
0
0
15
38
4.05
5.48
1.1
1.3
—
—
—
0
0
114
1632
0.59
5.40
4.7
5.3
0.6
0.7
%
0.59
104
1523
121
1698
0.60
5.24
4.6
5.2
2.5
2.7
%
0.26
115
1588
129
1772
0.61
5.06
4.6
5.2
28.3
29.9
%
1.05
122
1675
159
1155
1.59
4.96
1.9
1.7
—
—
—
0
0
79
478
1.80
4.90
2.7
2.1
12903.2
4075.2
u/l
0.86
26
186
215
1677
1.56
4.89
4.6
4.0
6.4
6.2
mmol/l
1.14
187
1494
153
1111
1.58
4.74
3.7
4.2
35.6
37.2
g/l
2.62
147
1049
130
1759
0.63
4.64
4.2
5.0
58.6
56.6
%
1.19
124
1665
124
871
1.59
4.37
2.8
2.4
95.8
16.2
ng/l
0.43
43
304
126
1700
0.64
4.35
4.7
5.4
7.3
7.7
%
0.73
120
1607
373
3351
1.77
4.34
3.4
2.8
1.3
1.2
mmol/l
2.56
364
3212
24
96
2.59
4.29
2.2
1.3
—
—
—
0
0
359
3204
1.67
4.13
4.8
4.4
14.6
14.2
pmol/l
3.31
344
3059
30
141
2.21
3.80
1.5
1.9
24.9
20.3
s
0.61
24
120
21
462
0.43
3.73
1.1
1.2
—
—
—
0
0
300
3352
0.67
3.66
11.3
11.0
13.5
13.5
%
0.03
295
3297
368
3339
1.65
3.57
3.6
3.1
5.5
5.5
mmol/l
0.19
351
3181
27
125
2.24
3.56
2.9
2.2
4.3
4.3
umol/l
0.01
18
91
382
3501
1.72
3.55
3.6
3.1
1.5
1.6
mmol/l
4.47
373
3369
38
203
1.95
3.47
1.1
1.4
—
—
—
0
0
382
3513
1.69
3.34
3.7
3.1
4.8
4.8
mmol/l
0.03
371
3389
27
129
2.17
3.31
6.9
7.4
—
—
—
0
0
75
1079
0.63
3.26
5.0
5.3
—
—
—
0
0
389
3605
1.72
3.17
5.4
5.0
1.7
2.0
mu/l
0.49
375
3472
123
918
1.47
3.16
2.8
2.0
—
—
—
0
0
17
68
2.56
3.08
1.3
1.4
—
—
—
0
0
81
559
1.55
3.01
2.1
2.2
7.7
10.0
e6/l
0.58
72
489
382
3538
1.63
2.94
4.0
3.3
3.0
2.9
mmol/l
1.48
370
3396
49
300
1.71
2.93
1.4
1.4
—
—
—
0
0
128
982
1.43
2.81
3.9
3.7
—
—
—
0
0
399
3749
1.74
2.75
10.4
9.3
15.9
17.6
mg/l
0.69
313
2824
7
14
5.06
2.74
1.4
1.3
—
—
—
0
0
29
154
1.95
2.73
3.6
7.3
5.5
6.5
mmol/l
0.55
29
148
100
737
1.46
2.71
2.9
2.5
0.2
0.3
e6/l
0.16
78
539
29
155
1.93
2.68
2.6
2.9
—
—
—
0
0
20
389
0.49
2.57
1.1
1.2
—
—
—
0
0
126
978
1.41
2.57
1.9
1.6
—
—
—
0
0
28
152
1.90
2.49
1.7
2.1
66.3
67.9
g/l
0.68
28
141
48
307
1.63
2.46
1.4
1.5
—
—
—
0
0
10
249
0.39
2.43
1.5
1.3
—
—
—
0
0
100
752
1.43
2.42
2.8
2.5
—
—
—
0
0
47
302
1.62
2.37
1.4
1.4
—
—
—
0
0
40
621
0.61
2.36
2.0
2.4
—
—
—
0
0
10
35
2.90
2.32
1.1
1.1
—
—
—
0
0
281
2505
1.34
2.25
4.5
3.7
—
—
—
0
0
0
62
0.00
2.24
0.0
6.7
—
364.4
—
0
53
28
158
1.83
2.23
6.3
5.7
1.2
1.2
mmol/l
0.09
28
152
347
3696
0.70
2.23
10.7
10.0
39.3
39.6
%
0.34
285
3182
120
947
1.37
2.18
3.0
2.4
56.1
55.3
u/l
0.07
110
893
129
1578
0.74
2.15
6.2
7.0
0.0
0.0
e9/l
0.65
103
1304
10
37
2.74
2.11
1.5
1.3
—
—
—
0
0
11
43
2.60
2.11
1.5
1.2
—
—
—
0
0
18
89
2.07
2.09
1.2
1.5
3.5
3.5
mmol/l
0.03
18
84
29
170
1.76
2.06
2.0
1.6
—
—
—
0
0
26
150
1.78
1.95
2.7
2.7
1.7
1.6
mmol/l
0.07
19
117
416
4004
1.81
1.93
10.2
8.7
—
—
—
0
0
133
1087
1.32
1.89
3.4
3.0
29.3
38.3
e6/l
0.32
84
666
13
60
2.20
1.79
1.5
1.4
—
—
—
0
0
8
31
2.61
1.66
1.5
1.3
—
—
—
0
0
201
1759
1.26
1.64
4.2
3.8
—
—
—
0
0
291
2662
1.28
1.64
3.3
3.5
9.3
8.7
mm/h
0.64
275
2529
8
32
2.53
1.60
1.6
1.5
249.6
358.9
pmol/l
—
8
19
29
437
0.64
1.54
1.0
1.1
—
—
—
0
0
163
1408
1.25
1.45
2.2
2.0
—
—
—
0
0
13
66
2.00
1.45
3.1
2.8
—
—
—
0
0
14
74
1.92
1.40
1.2
1.1
—
—
—
0
0
5
120
0.41
1.39
1.0
1.3
—
2.4
—
0
13
6
23
2.63
1.37
1.0
1.2
3122.5
1727.8
miu/ml
—
6
23
320
2990
1.26
1.36
4.3
3.6
37.4
36.9
mmol/mol
0.55
310
2871
177
1553
1.23
1.35
5.1
5.0
8.8
9.2
umol/l
0.28
163
1466
24
365
0.64
1.34
1.3
1.3
—
—
—
0
0
23
352
0.63
1.32
1.1
1.3
—
—
—
0
0
6
134
0.44
1.30
1.2
1.3
—
—
—
0
0
131
1117
1.25
1.29
4.6
4.7
1.2
1.2
mmol/l
4.54
126
1030
102
846
1.27
1.27
2.2
2.0
3.1
2.5
mg/l
1.92
97
732
35
487
0.69
1.27
1.2
1.7
—
—
—
0
0
15
250
0.59
1.23
1.5
3.3
—
—
—
0
0
80
647
1.29
1.22
1.9
1.5
—
—
—
0
0
76
933
0.78
1.22
1.3
1.4
2.2
2.0
g/l
0.28
58
620
21
316
0.65
1.14
3.0
3.0
—
—
—
0
0
430
4233
1.99
1.11
16.5
13.9
89.3
90.0
fl
2.99
430
4198
6
123
0.48
1.06
1.0
1.1
—
—
—
0
0
6
123
0.48
1.06
1.0
1.1
—
—
—
0
0
7
33
2.14
1.06
1.1
1.1
—
—
—
0
0
15
238
0.62
1.04
2.7
1.5
—
—
—
0
0
23
155
1.51
1.03
1.2
1.2
—
—
—
0
0
36
266
1.39
1.02
3.6
5.2
1.0
1.0
mmol/l
0.21
36
247
15
91
1.67
1.02
1.4
1.3
—
—
—
0
0
7
133
0.52
1.00
1.0
1.1
—
—
—
0
0
430
4237
1.93
1.00
16.6
14.0
133.3
133.2
g/l
0.07
430
4204
430
4235
1.96
1.00
16.5
13.8
29.8
30.0
pg
1.25
430
4199
15
92
1.65
0.98
4.7
2.7
9.9
9.1
mg/l
0.21
15
83
17
257
0.65
0.96
1.4
1.2
—
—
—
0
0
8
142
0.56
0.95
2.6
1.7
—
—
—
0
0
94
1095
0.82
0.94
1.7
1.7
98.6
99.5
pmol/l
0.07
55
637
64
777
0.79
0.94
1.5
1.6
1.4
1.3
mmol/l
0.44
59
711
30
401
0.73
0.89
1.1
1.3
—
—
—
0
0
96
1107
0.83
0.87
2.4
2.4
—
—
—
0
0
13
80
1.64
0.85
1.2
1.7
—
—
—
0
0
26
188
1.41
0.85
1.0
1.3
0.4
2.5
u/ml
—
5
12
8
47
1.71
0.81
1.9
1.6
—
—
—
0
0
12
74
1.64
0.79
1.2
1.2
100.4
217.2
u/ml
—
7
53
95
825
1.19
0.78
3.2
2.6
12.6
103.5
e6/l
1.62
73
609
0
28
0.00
0.76
0.0
2.6
—
42.0
—
0
5
0
28
0.00
0.76
0.0
1.2
—
31.2
—
0
28
5
24
2.10
0.74
1.0
1.5
91.8
91.5
%
—
5
24
7
39
1.81
0.73
1.1
1.4
7.1
6.0
g/l
—
7
28
7
39
1.81
0.73
1.1
1.4
3.4
2.7
g/l
—
7
27
7
39
1.81
0.73
1.1
1.5
—
—
—
0
0
7
39
1.81
0.73
1.1
1.4
0.3
0.4
g/l
—
7
28
12
76
1.60
0.72
1.1
1.2
—
—
—
0
0
5
26
1.93
0.71
1.0
1.2
—
—
—
0
0
20
144
1.41
0.69
2.1
2.3
2.4
5.9
iu/l
—
9
66
10
61
1.65
0.69
1.1
1.4
0.7
0.6
g/l
—
10
46
11
168
0.65
0.69
1.5
2.7
1.2
1.2
mmol/l
0.95
11
141
8
129
0.61
0.65
2.9
2.0
—
—
—
0
0
142
1295
1.14
0.63
4.6
5.4
1.2
1.2
mmol/l
2.30
134
1112
97
1087
0.86
0.62
1.2
1.3
0.6
1.4
u/ml
1.21
35
301
64
549
1.19
0.62
3.3
3.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
85
749
1.17
0.60
2.5
3.0
7.4
7.4
ph
—
8
126
0
21
0.00
0.60
0.0
3.5
—
—
—
0
0
8
52
1.55
0.59
1.0
1.1
—
0.3
—
0
21
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
7
116
0.60
0.58
1.9
2.9
0.2
0.1
e6/l
—
7
110
18
133
1.37
0.56
1.1
1.1
0.9
4.6
u/ml
—
7
65
8
125
0.63
0.55
3.1
2.1
—
—
—
0
0
9
60
1.51
0.54
1.0
1.1
—
—
—
0
0
9
61
1.49
0.54
1.7
1.4
29.5
32.3
nmol/l
—
9
47
6
39
1.55
0.53
1.2
1.5
3.2
4.8
u/ml
—
6
30
33
269
1.25
0.53
1.5
1.4
258.8
234.6
miu/ml
0.14
17
147
9
64
1.41
0.51
1.1
1.1
—
—
—
0
0
47
400
1.20
0.51
1.7
1.4
—
—
—
0
0
150
1611
0.90
0.50
1.7
1.9
—
—
—
0
0
16
119
1.36
0.49
1.1
1.3
—
—
—
0
0
7
46
1.53
0.48
1.3
1.3
—
—
—
0
0
12
85
1.42
0.47
1.0
1.1
—
12.3
—
0
8
143
1535
0.90
0.47
1.8
2.0
—
—
—
0
0
84
756
1.14
0.46
1.3
1.3
7.3
12.3
u/ml
0.36
48
330
15
198
0.75
0.46
3.0
2.2
—
—
—
0
0
17
220
0.76
0.46
2.3
2.3
0.2
0.2
g/l
0.11
17
211
14
103
1.37
0.45
4.5
5.8
23.6
24.4
mmol/l
0.51
14
103
15
113
1.34
0.43
1.0
1.9
—
—
—
0
0
6
94
0.63
0.42
1.0
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
216
2060
1.10
0.41
6.4
7.9
4.4
4.0
e9/l
1.91
193
1828
14
183
0.76
0.41
1.6
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.7
—
—
—
0
0
85
775
1.12
0.39
1.3
1.3
20.0
22.0
iu/ml
0.10
21
248
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
6.6
—
162.5
—
0
13
17
214
0.79
0.39
4.4
2.1
—
—
—
0
0
12
89
1.36
0.38
15.0
15.6
—
—
—
0
0
9
70
1.29
0.37
1.1
1.0
—
—
—
0
0
81
740
1.12
0.36
2.7
3.2
101.8
99.5
%
0.43
75
719
6
42
1.43
0.35
1.5
1.9
5.2
5.0
kpa
—
6
42
6
42
1.43
0.35
1.5
1.9
9.6
9.7
kpa
—
6
42
6
42
1.43
0.35
1.5
1.8
—
—
—
0
0
11
145
0.75
0.35
1.5
1.9
1.3
1.2
g/l
0.84
11
136
44
388
1.15
0.34
2.2
2.0
—
—
—
0
0
234
2255
1.08
0.33
3.2
2.9
57.9
57.4
ug/l
0.04
229
2151
6
47
1.28
0.32
1.5
2.0
7.4
7.4
ph
—
6
42
15
186
0.80
0.31
2.5
3.3
67.6
65.0
ng/l
0.10
15
174
254
2460
1.08
0.31
6.1
6.1
71.8
71.7
u/l
0.01
238
2327
117
1103
1.08
0.28
1.7
1.9
—
—
—
0
0
9
116
0.77
0.27
1.2
1.2
—
—
—
0
0
58
633
0.90
0.27
1.2
1.4
298.2
544.3
titre
1.17
11
135
71
657
1.10
0.26
1.2
1.3
—
—
—
0
0
23
267
0.85
0.26
2.2
1.7
—
—
—
0
0
127
1336
0.93
0.26
1.8
1.7
—
—
—
0
0
11
137
0.80
0.24
1.5
2.0
0.2
0.2
g/l
0.19
11
129
22
254
0.86
0.24
1.8
2.5
10.8
10.3
g/l
0.46
22
237
5
39
1.29
0.23
1.0
1.2
37.7
29.0
mg/l
—
5
28
5
39
1.29
0.23
1.0
1.4
—
—
—
0
0
5
41
1.22
0.22
1.4
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
17.8
—
0
10
0
12
0.00
0.21
0.0
1.0
—
5.9
—
0
12
0
12
0.00
0.21
0.0
1.0
—
7.1
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
11
89
1.24
0.21
2.7
2.0
12.9
13.2
%
0.43
11
89
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
35
385
0.90
0.20
1.3
1.3
—
—
—
0
0
79
748
1.07
0.18
1.5
1.4
—
—
—
0
0
5
66
0.75
0.17
2.0
1.5
—
—
—
0
0
185
1803
1.05
0.15
5.0
5.3
0.5
0.5
e9/l
0.60
169
1616
10
119
0.84
0.15
2.3
2.1
—
—
—
0
0
88
842
1.06
0.15
3.4
4.3
1.0
1.0
inr
0.12
19
306
11
93
1.19
0.14
1.0
1.0
—
0.1
—
0
18
7
90
0.77
0.14
1.3
1.1
—
—
—
0
0
41
439
0.93
0.14
3.2
2.5
1095.6
548.1
ng/l
0.20
21
184
185
1810
1.04
0.13
5.0
5.3
0.0
0.0
e9/l
1.91
170
1615
5
44
1.14
0.10
1.0
1.0
—
0.2
—
0
8
57
594
0.95
0.09
2.4
2.3
66.0
71.6
ug/g
0.16
44
463
6
58
1.03
0.08
2.0
1.6
—
—
—
0
0
5
62
0.80
0.08
1.0
1.1
—
7783.7
—
0
16
7
64
1.10
0.08
1.3
1.3
0.8
2.2
nmol/l
—
7
55
7
68
1.03
0.08
3.1
2.5
—
—
—
0
0
27
285
0.94
0.07
1.2
1.3
—
19.8
—
0
11
190
1880
1.02
0.05
5.0
5.3
2.0
2.0
e9/l
0.14
177
1709
191
1890
1.02
0.05
5.0
5.7
0.2
0.2
e9/l
1.43
178
1713
45
464
0.97
0.05
1.1
1.2
162.2
162.1
iu/ml
0.00
27
197
22
210
1.05
0.03
1.0
1.1
—
—
—
0
0
28
290
0.96
0.03
2.0
1.6
—
—
—
0
0
28
288
0.97
0.02
2.0
1.6
—
—
—
0
0
28
288
0.97
0.02
2.0
1.6
—
—
—
0
0
28
273
1.03
0.01
1.2
1.2
—
—
—
0
0
19
196
0.97
0.00
1.8
1.8
1.2
1.4
g/l
0.99
19
186
11
105
1.05
0.00
2.9
2.5
47.0
77.0
ng/l
1.28
11
94
25
252
0.99
0.00
1.0
1.1
—
—
—
0
0
52
521
1.00
0.00
2.1
2.4
522.2
536.3
mosm/kgh2o
0.17
46
448
28
283
0.99
0.00
2.0
1.6
—
—
—
0
0
28
275
1.02
0.00
1.3
1.3
—
—
—
0
0
89
894
0.99
0.00
5.1
5.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
8.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
124.4
—
0
6
0
6
0.00
0.00
0.0
1.3
—
51.6
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
1.2
—
0
9
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
0
8
0.00
0.00
0.0
4.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
7
78
0.90
0.00
3.3
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
4.4
—
0
9
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
0.00
2.8
2.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
8
81
0.99
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_HYPERT_UNS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_HYPERT_UNS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_MATERN_HYPERT_UNS – Unspecified maternal hypertension

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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