brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
217 |
4. Check minimum number of eventsNone |
217 |
5. Include endpointsNone |
217 |
6. Filter based on genotype QC (FinnGen only) |
217 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D31
- Name in latin
- Neoplasma benignum orbitae non specificatum
Similar endpoints
↥List of similar endpoints to Benign neoplasm: Orbit, unspecified based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Orbit, unspecified
- Benign neoplasm of eye and adnexa
- Benign neoplasm of eye and adnexa
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1703 | 988 | 701 |
Only index persons | 1480 | 873 | 607 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.03 | 0.02 |
Only index persons | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 50.29 | 50.56 | 49.71 |
Only index persons | 49.65 | 50.35 | 48.65 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 217 | 144 | 73 |
Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
Median age at first event (years) | 54.74 | 52.89 | 58.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 187
- Matched controls
- 1870
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_ORBIT_NOS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_ORBIT_NOS | 1.274 [1.0, 1.63] | 0.051 |
Birth year | 0.99 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 108 out of 648 females with CD2_BENIGN_ORBIT_NOS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_ORBIT_NOS | 1.337 [1.0, 1.79] | 0.053 |
Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 444 males with CD2_BENIGN_ORBIT_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_ORBIT_NOS.N-year risk | Females | Males |
---|---|---|
1 | 0.107% | 0.224% |
5 | 0.624% | 1.468% |
10 | 1.459% | 3.587% |
15 | 2.954% | 6.69% |
20 | 5.353% | 11.526% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_ORBIT_NOS – Benign neoplasm: Orbit, unspecified
GWS hits: -