Benign neoplasm: Orbit, unspecified

CD2_BENIGN_ORBIT_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.6&
  • Hospital discharge: ICD-9 2241
  • Hospital discharge: ICD-8 22405
  • Cause of death: ICD-10 D31.6&
  • Cause of death: ICD-9 2241
  • Cause of death: ICD-8 22405

2 out of 7 registries used, show all original rules.

227

4. Check minimum number of events

None

227

5. Include endpoints

None

227

6. Filter based on genotype QC (FinnGen only)

220

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum orbitae non specificatum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1703 988 701
Only index persons 1480 873 607
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 50.29 50.56 49.71
Only index persons 49.65 50.35 48.65

-FinnGen-

Key figures

All Female Male
Number of individuals 220 145 75
Unadjusted period prevalence (%) 0.05 0.05 0.03
Median age at first event (years) 54.78 52.92 58.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
227
Matched controls
2270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
+∞
262.3
198
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
286.7
46.9
46
*
CAA30
NOMESCO Finland
Biopsy of orbit
+∞
36.4
34
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.1
23.8
47
93
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.0
20.0
26
32
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
19.0
18
*
H05.2
ICD-10 Finland
Exophthalmic conditions
109.2
18.9
20
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
+∞
17.9
17
*
22405
ICD-8 Finland
Benign neoplasm of eye, Orbitae
+∞
16.9
16
*
2241A
ICD-9 Finland
Benign neoplasm of eye, Orbit
+∞
16.9
16
*
XCK00
NOMESCO Finland
Perimetry
5.1
14.8
34
76
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
14.4
68
257
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
45.7
14.3
17
*
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
36.5
13.7
17
5
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
+∞
12.6
12
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.7
11.9
29
68
CAB10
NOMESCO Finland
Lateral orbitotomy with excision of lesion
+∞
11.6
11
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
11.4
125
726
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
16.6
11.0
17
11
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
8.1
10.5
23
31
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
27.4
9.9
13
5
XCK10
NOMESCO Finland
Photography of fundus of eye
3.5
9.9
38
124
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
9.9
123
742
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
104.2
9.5
10
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
9.4
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
9.4
104
592
H57.1
ICD-10 Finland
Ocular pain
4.9
9.3
21
46
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
14.8
8.8
14
10
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
17.1
8.7
13
8
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
8.5
41
154
CS494
NOMESCO Finland
Other visual field testing
7.6
8.5
19
27
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
8.4
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
8.3
74
379
WX002
NOMESCO Finland
Sedation and analgesia
2.5
8.1
59
275
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
7.9
97
567
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
7.6
50
221
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
82.7
7.5
8
*
AA1AD
NOMESCO Finland
CT of head and brain
2.3
7.3
79
435
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
+∞
7.3
7
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
7.1
34
126
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
23.3
6.7
9
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
12.8
6.7
11
9
ZXA05
NOMESCO Finland
Left side
2.2
6.5
68
368
D31.5
ICD-10 Finland
Benign neoplasm: Lacrimal gland and duct
+∞
6.3
6
*
CAW99
NOMESCO Finland
Other operation on orbit
+∞
6.3
6
*
C69.63
ICD-10 Finland
Malignant tumor of orbital carcinoma
+∞
6.3
6
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
6.2
170
1306
CBA10
NOMESCO Finland
Biopsy of eyelid
13.0
6.1
10
8
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.3
6.1
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
39
154
2.85
7.33
1.3
1.3
—
—
—
0
0
150
1078
2.15
6.87
8.3
8.8
4.20
4.08
e9/l
0.23
125
961
121
814
2.04
6.48
5.5
6.2
1.21
1.22
mmol/l
0.62
112
742
133
934
2.02
6.23
5.5
5.4
2.15
1.89
e9/l
0.37
117
850
130
907
2.01
6.19
5.5
5.3
0.58
0.57
e9/l
0.31
111
807
130
909
2.01
6.13
5.5
5.3
0.04
0.04
e9/l
0.06
111
807
131
939
1.93
5.53
5.7
5.5
0.20
0.18
e9/l
0.53
114
847
215
1884
3.67
5.18
16.0
14.0
21.77
22.73
mg/l
0.15
186
1471
119
845
1.86
4.99
15.0
13.9
1.29
1.22
inr
0.24
23
259
123
887
1.84
4.87
6.9
7.1
1.21
1.21
mmol/l
0.17
108
752
121
875
1.82
4.69
6.4
5.5
26.45
27.69
%
0.62
115
831
115
820
1.82
4.66
6.3
5.5
0.76
0.67
%
0.98
109
769
120
867
1.81
4.65
6.0
5.3
57.65
57.60
%
0.02
114
823
44
228
2.15
4.56
1.3
1.3
440.00
542.86
titre
—
10
56
171
1386
1.95
4.50
3.9
3.9
12.23
11.61
mm/h
0.25
160
1262
117
845
1.79
4.49
6.3
5.5
3.21
2.79
%
0.90
110
798
117
850
1.78
4.36
6.7
5.8
8.92
8.51
%
0.68
111
806
41
213
2.13
4.22
1.3
1.2
—
—
—
0
0
160
1292
1.81
3.98
4.7
4.6
—
—
—
0
0
73
472
1.81
3.96
5.3
6.3
—
—
—
0
0
102
728
1.73
3.93
4.8
3.7
5.63
5.74
ph
—
8
54
123
929
1.71
3.82
6.3
5.3
0.00
0.00
estimate
-0.00
16
186
122
921
1.70
3.78
4.8
4.0
0.00
0.01
estimate
0.50
16
199
124
942
1.70
3.74
4.9
4.0
0.00
0.00
estimate
-0.00
16
183
104
756
1.69
3.68
2.1
1.9
93.89
95.85
pmol/l
0.17
54
369
114
851
1.68
3.64
6.4
6.0
—
—
—
0
0
198
1733
2.12
3.58
5.6
4.7
1.74
1.90
mu/l
1.47
183
1573
69
453
1.75
3.50
1.5
1.5
23.56
21.85
nmol/l
0.36
62
376
10
22
4.70
3.47
1.1
1.0
—
—
—
0
0
100
731
1.66
3.40
2.5
2.0
—
—
—
0
0
169
1425
1.73
3.20
4.7
4.0
14.68
14.79
pmol/l
0.24
157
1274
13
40
3.38
3.20
1.0
1.1
—
—
—
0
0
64
422
1.72
3.17
5.9
3.9
—
—
—
0
0
82
578
1.66
3.16
2.0
2.3
—
—
—
0
0
211
1920
2.40
3.02
18.8
16.4
139.52
139.68
mmol/l
0.47
211
1864
26
129
2.15
3.00
1.3
1.4
—
—
—
0
0
151
1252
1.62
2.89
6.5
4.8
—
2794.08
—
0
24
103
783
1.58
2.85
5.6
4.6
36.12
35.79
g/l
0.28
93
735
8
18
4.57
2.82
1.1
1.1
—
—
—
0
0
11
34
3.35
2.76
1.2
1.2
2.17
4.44
u/ml
—
6
16
13
49
2.75
2.67
1.6
2.9
—
—
—
0
0
7
15
4.78
2.61
1.3
1.0
—
—
—
0
0
36
212
1.83
2.59
7.3
9.9
0.49
1.29
mmol/l
1.46
29
173
75
541
1.58
2.55
3.4
3.8
7.40
7.40
ph
—
7
104
220
2084
2.80
2.41
25.3
20.4
39.80
40.06
%
0.26
214
1959
214
1988
2.34
2.39
11.3
10.1
23.79
25.25
u/l
1.06
208
1914
45
659
0.60
2.38
3.2
2.9
—
—
—
0
0
220
2088
2.74
2.28
24.9
20.4
133.47
134.58
g/l
0.57
220
2055
46
302
1.66
2.27
3.5
2.7
4.90
2.78
e6/l
0.29
16
169
220
2087
2.76
2.27
24.8
20.3
7.04
6.64
e9/l
1.03
213
2029
7
18
3.98
2.27
3.6
2.7
—
—
—
0
0
220
2086
2.77
2.27
24.9
20.3
4.45
4.47
e12/l
0.20
213
2027
220
2086
2.77
2.27
24.7
20.2
30.14
30.28
pg
0.61
220
2054
220
2086
2.77
2.27
24.8
20.3
90.65
91.04
fl
0.62
220
2054
59
413
1.58
2.25
2.4
1.8
1.40
1.20
mg/l
0.16
46
319
166
1445
1.55
2.25
7.6
7.2
74.56
76.78
u/l
0.37
160
1354
37
230
1.73
2.23
7.0
6.7
105.59
104.09
mmol/l
1.38
37
230
72
529
1.53
2.22
3.4
2.9
0.35
0.56
e6/l
0.59
44
397
71
523
1.52
2.16
3.4
2.8
—
—
—
0
0
45
298
1.64
2.15
1.7
1.6
—
—
—
0
0
51
352
1.58
2.06
4.7
3.8
21.53
262.21
ng/l
1.79
36
285
6
15
4.08
2.05
1.0
1.1
—
—
—
0
0
6
15
4.08
2.05
1.2
1.1
—
—
—
0
0
82
629
1.48
2.03
4.0
3.3
2.34
2.35
mmol/l
0.48
73
549
151
1303
1.47
2.01
4.0
3.8
—
—
—
0
0
7
21
3.40
1.98
1.1
1.4
—
—
—
0
0
16
78
2.13
1.96
1.4
1.9
—
—
—
0
0
8
28
2.92
1.88
1.3
1.2
—
—
—
0
0
100
809
1.42
1.83
8.0
9.6
0.00
0.00
e9/l
0.61
74
668
66
494
1.47
1.83
4.0
4.2
—
—
—
0
0
177
1591
1.51
1.80
22.4
17.7
332.75
332.18
g/l
0.38
177
1581
144
1248
1.42
1.76
2.8
3.2
35.84
45.63
u/l
1.76
134
1170
119
998
1.40
1.75
6.3
6.2
10.71
10.60
umol/l
0.05
114
940
15
75
2.07
1.74
3.7
3.7
—
—
—
0
0
6
19
3.21
1.67
1.5
3.7
—
—
—
0
0
180
1633
1.49
1.66
18.9
16.8
14.49
14.83
%
0.42
180
1606
77
604
1.42
1.65
5.3
3.3
—
—
—
0
0
15
77
2.02
1.63
3.5
3.6
—
—
—
0
0
20
114
1.83
1.62
2.6
2.4
9.41
13.17
nmol/l
1.09
15
106
190
1746
1.54
1.61
4.0
4.0
1.30
1.26
mmol/l
0.34
169
1598
25
153
1.71
1.61
6.6
3.4
—
—
—
0
0
8
32
2.55
1.61
1.0
1.2
—
—
—
0
0
197
1826
1.60
1.59
4.5
4.4
5.87
5.91
mmol/l
0.20
177
1666
23
138
1.74
1.59
9.3
8.8
—
—
—
0
0
197
1828
1.59
1.56
4.5
4.4
4.68
4.68
mmol/l
0.03
184
1689
36
245
1.56
1.55
1.3
1.3
—
—
—
0
0
33
220
1.59
1.55
1.7
1.5
—
—
—
0
0
0
44
0.00
1.53
0.0
1.1
—
—
—
0
0
200
1866
1.60
1.50
5.2
4.9
2.76
2.76
mmol/l
0.01
187
1711
26
165
1.65
1.48
3.9
4.0
—
—
—
0
0
88
718
1.37
1.47
3.9
3.8
20.08
43.55
ng/l
2.12
63
500
12
59
2.09
1.46
1.8
1.7
—
—
—
0
0
195
1816
1.52
1.40
4.5
4.4
1.46
1.50
mmol/l
0.47
178
1672
0
38
0.00
1.35
0.0
2.1
—
—
—
0
0
53
405
1.40
1.30
6.2
4.5
1.02
1.02
kg/l
—
8
60
39
285
1.44
1.21
2.6
3.4
0.82
0.82
mmol/l
0.11
34
264
185
1720
1.41
1.19
5.8
5.7
39.16
39.74
mmol/mol
0.44
173
1602
41
304
1.43
1.18
1.2
1.2
12.32
37.79
iu/ml
2.63
11
92
207
1968
1.59
1.16
15.2
13.2
—
—
—
0
0
8
39
2.09
1.16
1.1
1.2
3.30
3.84
mmol/l
—
8
34
12
65
1.89
1.16
3.2
2.4
1150.92
8556.75
u/l
—
6
20
82
683
1.31
1.15
4.3
3.6
57.59
92.49
e6/l
0.45
47
486
10
51
2.01
1.13
3.5
5.1
48.11
24.57
mg/l
—
10
40
10
51
2.01
1.13
3.5
5.1
73.29
70.09
mg/l
—
10
40
27
187
1.50
1.10
3.8
3.9
2.28
42.22
ug/l
0.58
19
157
11
60
1.88
1.04
1.5
2.1
37.66
39.51
g/l
0.50
11
53
5
22
2.30
1.04
1.4
1.2
—
—
—
0
0
71
588
1.30
1.03
3.4
3.0
22.87
152.85
e6/l
0.64
44
457
7
35
2.03
1.01
3.6
1.6
—
—
—
0
0
39
297
1.38
0.98
1.2
1.2
1.18
11.08
u/ml
2.33
12
112
16
101
1.63
0.96
5.2
5.6
24.99
24.75
mmol/l
0.15
16
101
16
102
1.61
0.93
1.1
1.2
50.70
218.12
u/ml
2.70
16
92
33
247
1.39
0.92
3.1
2.3
21.81
22.64
%
0.13
28
207
27
195
1.44
0.91
1.1
1.3
—
—
—
0
0
94
817
1.26
0.91
3.3
2.6
94.87
108.35
ug/l
0.57
89
742
18
119
1.56
0.91
2.9
2.5
—
—
—
0
0
35
266
1.37
0.90
1.7
2.1
—
—
—
0
0
6
30
2.03
0.87
1.2
1.2
—
—
—
0
0
6
31
1.96
0.85
1.7
1.4
—
—
—
0
0
56
461
1.29
0.84
2.8
2.0
2.88
2.99
mg/l
0.18
45
392
14
90
1.59
0.80
12.1
15.2
—
—
—
0
0
43
344
1.31
0.80
1.6
1.6
1142.72
1200.78
nmol/l
0.16
33
254
0
25
0.00
0.79
0.0
1.4
—
—
—
0
0
0
26
0.00
0.79
0.0
1.4
—
0.45
—
0
21
44
357
1.29
0.74
2.1
1.9
—
—
—
0
0
5
25
2.02
0.73
1.2
1.1
—
—
—
0
0
9
57
1.60
0.72
1.0
1.4
—
—
—
0
0
44
359
1.28
0.71
3.7
2.6
2.45
2.45
mmol/l
0.04
37
311
5
26
1.94
0.71
1.0
1.2
—
—
—
0
0
13
85
1.56
0.70
2.3
1.9
—
—
—
0
0
7
117
0.59
0.70
1.4
1.5
—
—
—
0
0
18
128
1.44
0.68
3.7
7.9
—
—
—
0
0
28
216
1.34
0.67
1.5
1.4
—
—
—
0
0
23
172
1.38
0.67
1.3
1.4
—
—
—
0
0
13
88
1.51
0.62
2.5
2.3
0.74
0.66
%
0.39
13
88
8
51
1.59
0.61
2.4
2.7
1.44
1.61
mg/l
—
8
46
30
238
1.30
0.61
2.8
2.1
101.23
124.41
ug/g
0.25
23
185
16
114
1.43
0.60
3.3
3.1
—
7.42
—
0
18
0
21
0.00
0.60
0.0
4.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
27
212
1.31
0.59
1.7
1.8
—
—
—
0
0
26
203
1.32
0.59
2.3
1.6
—
—
—
0
0
6
35
1.73
0.58
1.2
1.2
—
—
—
0
0
59
511
1.21
0.57
3.8
3.1
1132.63
195.98
mg/l
0.41
35
331
6
36
1.68
0.57
1.3
1.4
—
—
—
0
0
8
55
1.47
0.56
1.3
1.2
—
—
—
0
0
63
550
1.20
0.56
3.2
3.0
7.73
7.50
mmol/l
0.16
54
468
19
142
1.37
0.56
1.8
4.5
0.00
0.26
%
—
7
43
13
91
1.45
0.54
2.5
2.3
1.18
1.15
%
0.05
13
91
18
135
1.36
0.53
2.2
4.4
0.88
0.46
%
—
8
42
20
153
1.34
0.52
1.8
4.4
0.75
0.89
%
—
8
54
9
64
1.42
0.52
1.4
1.9
1075.89
349.92
ug/l
—
9
58
35
292
1.23
0.49
2.7
3.1
0.99
0.78
ug/l
0.45
22
192
61
541
1.17
0.46
3.9
3.7
10.53
11.20
mg/mmol
0.04
34
341
45
390
1.19
0.44
1.4
1.7
407.16
453.92
pmol/l
0.59
37
319
11
78
1.43
0.44
1.1
1.2
—
—
—
0
0
5
32
1.57
0.42
1.6
1.2
—
—
—
0
0
16
123
1.32
0.41
1.6
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
5.6
—
—
—
0
0
60
539
1.15
0.39
1.4
1.5
—
—
—
0
0
17
135
1.28
0.36
2.2
4.5
0.00
0.24
%
—
5
37
6
44
1.37
0.34
1.2
1.1
—
—
—
0
0
18
147
1.24
0.32
2.2
2.9
75.67
72.69
e9/l
0.13
13
115
7
56
1.26
0.29
1.7
2.8
—
—
—
0
0
12
151
0.78
0.29
1.6
1.2
—
—
—
0
0
7
57
1.24
0.29
1.4
1.2
—
—
—
0
0
35
391
0.88
0.26
2.1
2.9
498.34
535.44
mosm/kgh2o
0.48
29
335
15
179
0.83
0.24
1.5
1.3
—
—
—
0
0
13
106
1.24
0.23
1.2
1.2
—
—
—
0
0
12
97
1.25
0.23
1.8
3.8
—
—
—
0
0
5
39
1.29
0.23
2.8
2.9
—
—
—
0
0
23
201
1.16
0.22
1.6
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
145.09
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
7
63
1.11
0.17
2.1
2.7
—
—
—
0
0
7
63
1.11
0.17
1.1
1.1
—
—
—
0
0
19
168
1.14
0.16
1.4
1.4
—
—
—
0
0
8
73
1.10
0.16
1.0
1.1
—
—
—
0
0
14
159
0.87
0.13
6.9
4.2
—
—
—
0
0
14
125
1.13
0.10
1.1
1.2
—
—
—
0
0
51
532
0.95
0.09
3.6
3.6
—
—
—
0
0
5
63
0.79
0.08
12.2
8.9
—
—
—
0
0
5
64
0.78
0.08
1.2
1.4
—
—
—
0
0
6
70
0.85
0.08
1.2
1.3
—
—
—
0
0
55
533
1.04
0.06
4.0
4.1
—
—
—
0
0
53
516
1.04
0.05
7.3
4.3
0.00
0.00
estimate
-0.00
16
183
43
417
1.04
0.04
1.3
1.3
1.00
0.97
u/ml
—
7
108
37
381
0.97
0.03
1.6
1.4
2.34
2.48
g/l
0.18
25
220
51
519
0.98
0.02
1.7
1.6
1.30
1.32
mmol/l
0.07
45
433
11
103
1.07
0.02
1.5
2.5
—
—
—
0
0
41
403
1.02
0.01
2.3
2.5
6.77
5.13
e6/l
0.31
36
365
14
139
1.01
0.00
2.4
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
41.60
—
0
5
6
69
0.87
-0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
33500.63
—
0
8
6
69
0.87
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
165.46
—
0
8
6
69
0.87
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
35.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_ORBIT_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_ORBIT_NOS 1.274 [1.0, 1.63] 0.051
Birth year 0.99 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 108 out of 648 females with CD2_BENIGN_ORBIT_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_ORBIT_NOS 1.337 [1.0, 1.79] 0.053
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 444 males with CD2_BENIGN_ORBIT_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_ORBIT_NOS.

N-year risk Females Males
1 0.107% 0.224%
5 0.624% 1.468%
10 1.459% 3.587%
15 2.954% 6.69%
20 5.353% 11.526%

Relationships between endpoints

Index endpoint: CD2_BENIGN_ORBIT_NOS – Benign neoplasm: Orbit, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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