This is a non-core endpoint: only basic statistics are computed.

Other transitory neonatal endocrine disorders

P16_OTH_TRANSITO_NEONTAL_ENDOCR_DISORD

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P72 Cause of death: ICD-10 — P72 2 out of 7 registries used, show all original rules.	9
4. Check minimum number of events None	9
5. Include endpoints None	9
6. Filter based on genotype QC (FinnGen only)	9

Control definitions (FinnGen only)

Control exclude: P16_TRANSITO_ENDOCR_METABOLIC_DISORD_SPECIFIC_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P7[0-4]
Name in latin: Aliae perturbationes transitoriae neonatales endocrinae

NAME	P16_OTH_TRANSITO_NEONTAL_ENDOCR_DISORD
CONTROL_EXCLUDE	P16_TRANSITO_ENDOCR_METABOLIC_DISORD_SPECIFIC_FETUS_NEWBO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P72
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P72
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other transitory neonatal endocrine disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	183	94	89
Only index persons	94	45	49
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	0.01	0.01
Only index persons	0.02	0.03	0.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	9	7	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	0.04	0.02	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

0.00

0.95

0.0

4.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.00

0.46

0.0

4.7

—

(3029937) Albumin [Presence] in Urine by Test strip

0.00

0.45

0.0

6.1

—

0.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.45

0.0

2.5

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.45

0.0

1.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.00

0.23

0.0

1.3

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.00

0.23

0.0

4.3

—

242.1

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.22

0.0

1.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.22

0.0

1.2

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.22

0.0

1.2

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

1.3

—

(4010399)

0.00

0.0

1.2

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.1

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.0

10.8

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

0.00

0.0

6.6

—

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.6

—

(3018133) Calcium [Moles/volume] in Urine

0.00

0.0

3.6

—

2.3

—

(40761535) Cells panel - Urine sediment

0.00

0.0

3.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

0.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

2.6

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

0.0

2.6

—

24.1

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

2.0

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

113.0

—

(3017732) Neutrophils [#/volume] in Blood

0.00

0.0

1.4

—

4.0

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.1

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

1.1

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.1

—

(3000492) Spirometry study

0.00

0.0

1.7

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

0.00

0.0

8.7

—

36.7

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.0

2.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.0

—

(40768797) Stomach Pathology biopsy report

0.00

0.0

1.2

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.0

—

(3022621) pH of Urine by Test strip

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_OTH_TRANSITO_NEONTAL_ENDOCR_DISORD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_TRANSITO_NEONTAL_ENDOCR_DISORD.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_OTH_TRANSITO_NEONTAL_ENDOCR_DISORD – Other transitory neonatal endocrine disorders

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Other transitory neonatal endocrine disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints