Diffuse (eosinophilic) fasciitis

M13_DIFFASCITIS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M35.4 Cause of death: ICD-10 — M35.4 2 out of 7 registries used, show all original rules.	53
4. Check minimum number of events None	53
5. Include endpoints None	53
6. Filter based on genotype QC (FinnGen only)	52

Control definitions (FinnGen only)

Control exclude: M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M35
Name in latin: Fasci[i]tis [eosinophila] diffusa

NAME	M13_DIFFASCITIS
CONTROL_EXCLUDE	M13_SYSTCONNECT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M354
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M354
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Diffuse (eosinophilic) fasciitis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	308	198	108
Only index persons	287	185	102
Unadjusted period prevalence (%)
Whole population	0.00	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	58.90	60.24	56.13
Only index persons	56.83	58.34	54.10

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	52	35	17
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	58.71	57.02	62.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
53: Matched controls
530

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M35.4

ICD-10 Finland

Diffuse (eosinophilic) fasciitis

+∞

73.2

L04AX03

ATC

methotrexate; systemic

22.5

30.0

202

Kela drug reimbursment

Connective tissue diseases, rheumatoid arthritis and comparable disease

19.6

27.6

H02AB06

ATC

prednisolone; systemic

17.8

15.0

185

P01BA02

ATC

hydroxychloroquine; oral

13.6

12.1

M35.9

ICD-10 Finland

Systemic involvement of connective tissue, unspecified

+∞

11.9

L04AD01

ATC

ciclosporin; systemic

120.7

9.8

NK4XE

NOMESCO Finland

Joint ultrasound examination not elsewhere classified

12.6

8.5

M05BA04

ATC

alendronic acid; oral

11.8

8.2

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

8.4

7.6

H02AB07

ATC

prednisone; oral

5.8

7.4

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

4.9

7.2

160

L04AX01

ATC

azathioprine; systemic

21.2

6.5

M35.8

ICD-10 Finland

Other specified systemic involvement of connective tissue

+∞

6.4

NXL00

NOMESCO Finland

Biopsy of muscle

+∞

6.4

L01BA01

ATC

methotrexate; systemic

17.7

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037522) Nuclear Ab [Titer] in Serum

10.67

16.94

1.6

1.3

152.00

342.22

titre

—

(40760892) CBC W Ordered Manual Differential panel - Blood

191

7.63

9.36

18.9

6.5

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

139

5.96

9.13

4.9

1.8

93.83

146.55

u/l

1.09

134

(3015171) Extractable nuclear Ab [Units/volume] in Serum

20.93

9.10

1.2

1.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

5.36

8.48

2.3

1.4

2.35

2.22

g/l

0.16

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

27.10

8.41

1.9

1.0

—

(3006504) Eosinophils/100 leukocytes in Blood

189

6.16

8.11

21.4

5.6

2.93

2.52

0.66

175

(3022096) Basophils/100 leukocytes in Blood

183

5.83

7.92

21.7

5.4

0.72

0.57

1.05

167

(3019069) Monocytes/100 leukocytes in Blood

192

6.01

7.88

21.8

6.1

9.12

8.47

0.82

179

(3002030) Lymphocytes/100 leukocytes in Blood

197

5.78

7.49

21.7

5.9

27.97

27.82

0.03

184

(3018010) Neutrophils/100 leukocytes in Blood

195

5.29

7.00

21.0

5.7

55.09

57.13

0.66

183

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

12.24

6.38

1.9

5.1

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

7.86

6.21

2.2

2.3

—

(3018418) pH of Serum or Plasma

145

4.05

5.86

4.3

5.0

7.40

7.41

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

207

4.35

5.60

6.5

6.7

1.23

1.22

mmol/l

0.31

191

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

13.21

5.52

1.2

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

7.12

5.49

1.8

4.5

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

11.73

5.25

2.1

6.0

0.00

g/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

223

4.24

5.20

7.6

4.7

0.00

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

224

4.20

5.14

5.2

3.5

0.00

estimate

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

9.18

5.12

2.8

1.8

16.19

9.68

mg/l

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

8.76

4.56

1.8

1.9

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.98

4.54

1.2

1.5

—

(3025159) Blasts/100 leukocytes in Blood

5.21

4.39

7.2

4.5

0.00

1.14

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

3.70

4.28

1.4

1.7

—

(3021440) Promyelocytes/100 leukocytes in Blood

5.03

4.27

7.3

4.3

0.00

0.25

—

(3009261) Glucose [Presence] in Urine by Test strip

231

3.61

4.26

5.4

3.6

0.00

estimate

—

(3017181) Myelocytes/100 leukocytes in Blood

4.63

4.20

6.9

4.1

0.83

1.14

—

(3013707) Erythrocyte sedimentation rate by Westergren method

349

4.97

4.05

13.6

3.7

11.13

11.86

mm/h

0.19

317

(3011397) Hemoglobin [Presence] in Urine by Test strip

103

3.18

3.96

4.7

3.5

—

(3002179) Metamyelocytes/100 leukocytes in Blood

4.54

3.68

7.8

4.2

0.50

0.44

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

11.05

3.59

1.0

1.2

—

(40768443) Skin Pathology biopsy report

5.79

3.55

1.0

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

3.32

3.53

1.3

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

4.35

3.32

1.2

1.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.34

3.08

3.0

3.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

372

4.07

2.95

17.5

7.8

67.67

79.45

u/l

1.85

342

(40760888) Immunoglobulin light chains.free panel - Serum

9.03

2.81

2.0

12.7

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

9.03

2.81

1.6

1.3

—

(3018095) Leukocytes [#/volume] in Urine

157

2.47

2.61

6.2

3.2

13.94

72.64

e6/l

1.58

115

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.29

2.58

1.4

1.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

315

2.93

2.49

10.7

4.1

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

6.75

2.42

1.2

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

6.75

2.42

1.2

1.4

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

6.75

2.42

3.6

2.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

6.75

2.42

1.8

1.5

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

5.05

2.34

1.3

1.1

—

(40758558) Short blood count panel - Blood

122

2.37

2.30

22.0

9.0

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

2.54

2.25

1.1

1.2

9.33

21.44

iu/ml

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

5.39

2.12

1.0

—

(36660697) Celiac disease serology panel - Serum

3.44

2.11

1.1

1.2

—

(3045414) Leukocytes [Presence] in Urine

4.36

2.10

1.7

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.56

1.67

8.9

4.7

2.02

1.96

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.57

1.52

1.1

1.5

—

(4035726) Immunohistochemistry procedure

2.37

1.42

1.4

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

127

1.92

1.38

5.8

3.8

0.00

estimate

—

(3002385) Erythrocyte distribution width [Ratio]

392

2.31

1.35

36.3

16.6

15.96

15.19

0.34

387

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.69

1.34

7.7

27.17

24.95

mmol/l

—

(40768804) Tissue Pathology biopsy report

182

1.84

1.32

2.2

2.0

—

(3000492) Spirometry study

2.44

1.15

1.6

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.14

1.15

1.9

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

351

1.95

1.12

3.7

4.0

14.56

14.78

pmol/l

0.27

318

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.52

1.11

1.6

1.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

199

1.73

1.11

3.4

4.7

34.57

35.88

g/l

0.66

191

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

163

1.73

1.08

4.1

2.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.89

0.99

2.1

1.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.37

0.97

1.2

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.20

0.92

1.5

2.0

—

(3042936) Bacteria identified in Isolate by Culture

1.87

0.91

1.8

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.12

0.90

1.5

2.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

180

1.61

0.87

5.9

3.7

—

(3044640) Blood type and Crossmatch panel - Blood

154

1.60

0.83

4.4

2.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.86

0.82

4.6

8.3

104.80

103.58

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

127

1.63

0.82

5.4

3.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.88

0.82

2.0

1.9

—

(3000494) Fungus identified in Specimen by Culture

1.79

0.75

1.1

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.02

0.72

2.2

1.8

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

265

1.52

0.71

6.5

6.7

10.62

10.99

umol/l

0.17

246

(36304419) Bacteria [Presence] in Urine

123

1.56

0.69

3.7

2.7

—

(3023368) Bacteria identified in Blood by Culture

115

1.56

0.67

7.1

3.9

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.80

0.65

7.6

10.9

0.66

0.78

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.80

0.65

7.6

11.1

89.88

93.93

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.80

0.65

7.6

10.9

1.22

1.54

—

(40768797) Stomach Pathology biopsy report

1.69

0.64

1.2

1.3

—

(1002224) Polysomnography panel

0.00

0.61

0.0

1.1

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.2

—

(3019060) Gas panel - Arterial blood

1.65

0.56

2.2

3.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

178

1.40

0.50

2.1

1.9

101.63

101.58

pmol/l

0.00

(3044889) 12 lead EKG panel

317

1.42

0.50

4.0

3.9

—

(3002256) Pathology report gross observation

1.49

0.48

1.0

1.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

189

1.38

0.48

4.8

3.6

16.03

33.22

ng/l

0.96

136

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.50

0.45

2.3

2.4

0.35

0.83

e6/l

—

(3026008) Bacteria identified in Urine by Culture

157

0.70

0.44

2.3

2.9

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.62

0.43

1.4

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.48

0.40

2.0

1.5

—

(40761535) Cells panel - Urine sediment

1.44

0.36

9.7

3.2

—

(3022145) Colonoscopy Study observation

1.37

0.32

1.6

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

261

1.25

0.27

2.2

2.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

223

1.23

0.24

2.9

2.4

—

(3022621) pH of Urine by Test strip

1.39

0.24

2.2

3.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.4

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.21

0.0

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

142

0.80

0.20

5.8

3.6

5.33

11.28

mg/mmol

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.6

—

63.71

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

0.75

0.18

4.0

2.4

2.47

2.46

g/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.13

0.17

2.9

2.4

19.36

13.17

umol/l

—

(3013512) EKG study

146

0.85

0.12

6.5

4.0

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

145

0.86

0.11

5.5

2.4

66.92

55.75

u/l

0.46

136

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.15

0.10

3.8

2.3

4.56

5.08

ug/l

—

(3019225) pH of Specimen

1.10

0.10

9.0

4.0

—

(40761511) CBC panel - Blood by Automated count

475

0.91

0.09

21.6

13.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.83

0.08

1.3

1.4

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

303

0.91

0.07

3.2

2.8

34.69

48.05

u/l

1.38

278

(3012516) Albumin [Mass/volume] in Urine

131

0.89

0.06

4.3

3.0

23.71

65.92

mg/l

—

(3003694) ABO and Rh group [Type] in Blood

129

1.12

0.06

1.7

1.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

118

0.91

0.03

3.0

2.0

—

(1761868) Lipid panel - Serum or Plasma

144

0.96

0.00

2.4

3.1

—

(3022217) INR in Platelet poor plasma by Coagulation assay

222

0.98

0.00

13.2

12.9

1.28

1.31

inr

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.0

2.4

—

8.85

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

0.00

0.0

2.4

—

24.79

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

2.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.3

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

3.1

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3021901) Oxygen saturation in Capillary blood

0.00

-0.00

0.0

2.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.0

—

32.16

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.6

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.5

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.0

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

99.40

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.3

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.2

—

189.55

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

-0.00

0.0

1.0

—

388.00

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

-0.00

0.0

2.0

—

1.42

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

3.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.1

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

91.62

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_DIFFASCITIS and mortality.

Females

Parameter	HR [95% CI]	p-value
M13_DIFFASCITIS	1.827 [1.31, 2.54]	< 0.001
Birth year	0.992 [0.98, 1.0]	0.086

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 174 females with M13_DIFFASCITIS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_DIFFASCITIS.

N-year risk	Females	Males
1	0.141%	No data
5	0.953%	No data
10	2.411%	No data
15	4.638%	No data
20	8.067%	No data

Relationships between endpoints

↥

Index endpoint: M13_DIFFASCITIS – Diffuse (eosinophilic) fasciitis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Diffuse (eosinophilic) fasciitis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints