Abscess of mediastinum

J10_ABSCMEDIASTINUM

Lung Abscess: Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — J85.3 Hospital discharge: ICD-9 — 5131 Cause of death: ICD-10 — J85.3 Cause of death: ICD-9 — 5131 2 out of 7 registries used, show all original rules.	62
4. Check minimum number of events None	62
5. Include endpoints None	62
6. Filter based on genotype QC (FinnGen only)	62

Control definitions (FinnGen only)

Control exclude: J10_NECROTIC

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: J85
Name in latin: Abscessus mediastini

NAME	J10_ABSCMEDIASTINUM
CONTROL_EXCLUDE	J10_NECROTIC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J853
HD_ICD_9	5131
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J853
COD_ICD_9	5131
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Abscess of mediastinum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	468	143	320
Only index persons	353	110	243
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	62.93	66.74	61.28
Only index persons	61.87	64.58	60.65

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	62	22	40
Unadjusted period prevalence (%)	0.01	0.01	0.02
Median age at first event (years)	65.85	61.50	68.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
599

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

J85.3

ICD-10 Finland

Abscess of mediastinum

+∞

76.3

GD1BD

NOMESCO Finland

Thorax extensive CT-examination

12.9

8.6

J98.5

ICD-10 Finland

Diseases of mediastinum, not elsewhere classified

+∞

8.5

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

7.8

8.3

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

5.8

7.8

FWC00

NOMESCO Finland

Reoperation for deep infection in surgery of heart and major thoracic vessels

90.9

7.6

ENA32

NOMESCO Finland

Incision of deep pharyngeal infection

+∞

7.4

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

7.3

6.4

K22.2

ICD-10 Finland

Oesophageal obstruction

+∞

6.4

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042936) Bacteria identified in Isolate by Culture

4.69

7.04

4.3

2.0

—

(3023368) Bacteria identified in Blood by Culture

154

3.44

5.43

8.8

4.9

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

4.60

5.14

2.2

1.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

5.36

5.00

2.4

2.9

0.9

1.5

1.04

(3019230) Fractional oxyhemoglobin in Venous blood

12.86

4.93

2.5

1.0

68.0

67.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

106

3.28

4.68

6.4

2.3

—

(3024928) Oxygen saturation in Venous blood

11.25

4.67

2.6

2.3

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

9.67

3.88

2.0

1.9

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

3.12

3.87

12.2

5.7

1.2

1.1

mmol/l

0.33

(3012095) Magnesium [Moles/volume] in Serum or Plasma

3.02

3.76

12.9

3.1

0.8

mmol/l

0.89

(3044640) Blood type and Crossmatch panel - Blood

149

2.78

3.73

6.8

2.6

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

3.89

3.69

1.8

1.4

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

6.88

3.63

1.1

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

197

2.61

3.36

7.2

4.4

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.07

3.35

2.4

3.1

130.2

127.4

g/l

—

(3000991) Gas panel - Venous blood

3.19

3.14

21.9

7.4

—

(3000494) Fungus identified in Specimen by Culture

3.03

3.06

2.1

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

10.71

3.03

1.4

1.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.70

3.02

1.9

1.8

—

(3005719) IgG [Mass/volume] in Serum or Plasma

3.30

2.94

2.7

2.9

9.7

10.1

g/l

0.13

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

6.50

2.76

1.2

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

6.50

2.76

1.2

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

5.11

2.68

1.4

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

5.11

2.68

1.4

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

5.90

2.61

1.2

1.1

—

(3012544) pH of Venous blood

2.83

2.59

4.7

3.9

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.13

2.53

7.5

1.9

207.5

222.3

ng/l

0.05

(3008757) Leukocyte morphology finding [Identifier] in Blood

6.67

2.41

1.4

2.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

4.24

2.32

1.1

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

2.80

2.26

2.8

3.6

6.5

ug/l

1.03

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.52

2.18

27.5

7.7

—

(42870588) Differential panel, method unspecified - Blood

181

2.13

2.18

15.9

5.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.81

2.12

1.7

1.8

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.86

2.03

2.0

1.6

0.8

1.0

g/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.41

1.94

2.1

1.8

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

3.79

1.88

2.3

1.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.47

1.81

1.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.39

1.81

2.5

1.7

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.91

1.79

1.8

1.5

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

3.57

1.79

1.0

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.51

1.75

1.3

1.5

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

4.08

1.75

1.0

1.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

4.08

1.75

1.0

1.2

—

(3025941) Bacteria identified in Stool by Culture

3.02

1.70

1.4

1.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.38

1.70

1.8

1.5

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

3.38

1.70

2.5

2.3

—

(3032080) INR in Blood by Coagulation assay

214

1.90

1.65

15.8

9.4

1.4

1.3

inr

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

3.21

1.62

1.2

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.23

1.57

2.0

1.6

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

3.30

1.46

1.4

1.3

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

1.99

1.46

5.1

2.3

1.5

1.2

mg/l

0.35

(3022313) Gas panel - Capillary blood

2.33

1.41

11.6

7.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.10

1.38

1.6

1.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

252

1.77

1.37

16.7

7.5

1.2

mmol/l

0.28

212

(36660697) Celiac disease serology panel - Serum

2.55

1.35

1.5

1.3

—

(3000492) Spirometry study

2.15

1.17

2.0

1.5

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

2.15

1.17

13.1

7.9

23.0

25.1

mmol/l

—

(4035726)

2.17

1.11

2.3

1.4

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

282

1.66

1.11

5.3

3.3

66.8

48.3

u/l

0.60

263

(40768797) Stomach Pathology biopsy report

1.95

1.10

1.4

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.07

1.08

28.9

8.9

24.1

24.5

mmol/l

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.02

1.06

1.9

4.1

61.3

66.4

g/l

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.92

1.05

8.8

3.7

4.9

12.9

umol/l

1.58

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.84

1.05

2.4

2.3

3.0

0.6

e6/l

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

2.38

1.05

1.0

6.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.02

1.03

11.6

10.9

—

(3020891) Body temperature

2.35

0.96

6.0

5.6

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

2.18

0.92

1.3

3.4

—

55.0

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

223

1.56

0.91

11.4

4.9

32.3

35.0

g/l

1.46

210

(3019225) pH of Specimen

1.89

0.88

6.6

4.2

—

(3002385) Erythrocyte distribution width [Ratio]

394

0.65

0.84

55.0

20.3

14.6

13.8

2.32

388

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.97

0.84

1.2

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

198

1.54

0.84

2.7

2.1

100.6

93.0

pmol/l

0.37

106

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.81

0.0

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.80

0.0

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.79

0.0

1.4

—

(36304419) Bacteria [Presence] in Urine

145

1.56

0.79

3.0

2.9

—

(3018095) Leukocytes [#/volume] in Urine

191

1.52

0.79

3.4

4.0

30.1

47.8

e6/l

0.43

138

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.27

0.78

2.4

2.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

330

1.49

0.73

3.8

3.5

14.8

pmol/l

0.01

297

(3037467) Urinalysis macro (dipstick) panel - Urine

321

1.47

0.71

6.3

4.3

—

(3030467) Casts [#/volume] in Urine by Automated count

149

1.51

0.69

3.0

2.8

0.1

0.3

e6/l

2.03

111

(3019060) Gas panel - Arterial blood

1.71

0.69

5.3

3.6

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.79

0.65

2.4

3.3

—

(3022145) Colonoscopy Study observation

1.69

0.64

1.5

1.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.72

0.63

1.6

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

168

0.65

0.61

2.9

4.2

24.7

21.6

—

(4034850)

0.00

0.61

0.0

21.9

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.61

0.0

2.9

—

14.8

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.59

0.0

2.6

—

123.9

—

(1761868) Lipid panel - Serum or Plasma

155

0.65

0.58

2.0

3.2

—

(3009343) pH of Capillary blood

1.58

0.58

11.8

6.4

—

7.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

110

1.48

0.55

9.5

4.0

—

(3044889) 12 lead EKG panel

333

0.76

0.44

7.0

4.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

106

1.41

0.44

6.2

6.3

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

0.7

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

6.1

—

32.9

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.40

0.40

17.1

4.5

246.0

257.3

u/l

—

(40761535) Cells panel - Urine sediment

1.47

0.40

8.2

3.5

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.44

0.36

2.2

3.9

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.34

0.34

2.0

3.3

25.0

29.2

u/l

—

(3000963) Hemoglobin [Mass/volume] in Blood

509

0.75

0.34

59.9

24.0

121.7

133.7

g/l

3.98

498

(3024731) MCV [Entitic volume]

509

0.75

0.34

59.0

23.8

91.1

90.9

0.09

499

(3035941) MCH [Entitic mass]

509

0.75

0.34

58.9

23.8

30.0

30.2

0.29

499

(40761511) CBC panel - Blood by Automated count

480

0.77

0.32

32.8

15.3

—

(40758558) Short blood count panel - Blood

142

1.27

0.28

25.7

7.5

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

152

1.26

0.28

3.8

2.0

172.4

279.5

u/l

0.39

144

(3026008) Bacteria identified in Urine by Culture

143

1.26

0.27

3.3

3.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

271

1.21

0.25

2.8

2.9

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.21

0.0

1.5

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

1.4

—

91.6

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

483

0.82

0.21

50.8

19.4

4.0

mmol/l

0.79

471

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.6

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.1

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.2

—

0.5

—

(3002256) Pathology report gross observation

1.19

0.18

1.4

1.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.22

0.17

1.3

1.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

480

0.84

0.17

48.9

19.5

138.8

139.6

mmol/l

1.23

467

(3035350) Ketones [Presence] in Urine by Test strip

238

1.16

0.17

6.7

4.0

0.0

estimate

—

(3002582) Erythrocytes [#/volume] in Urine

170

1.17

0.16

3.0

3.3

178.0

410.8

e6/l

0.24

131

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

194

1.12

0.11

4.3

3.3

—

(40761536) Microorganisms panel - Urine sediment

1.18

0.10

3.2

3.8

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

484

0.88

0.09

26.1

11.3

30.1

25.6

u/l

0.37

467

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.82

0.08

1.8

1.7

449.8

355.8

nmol/l

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

483

0.89

0.08

45.8

19.6

84.9

83.0

umol/l

0.10

483

(3003694) ABO and Rh group [Type] in Blood

108

1.14

0.08

2.8

1.3

—

(40768804) Tissue Pathology biopsy report

179

1.09

0.05

3.7

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

130

0.90

0.05

2.4

3.8

—

(3013512) EKG study

141

1.08

0.04

5.2

4.7

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

421

0.99

0.00

5.4

4.3

2.5

2.1

mu/l

0.80

372

(3009542) Hematocrit [Volume Fraction] of Blood

411

0.99

0.00

52.5

16.6

36.5

39.8

2.59

301

(3031040) Bacteria [#/volume] in Urine by Automated count

309

1.01

0.00

7.1

4.6

—

436.2

—

(3029937) Albumin [Presence] in Urine by Test strip

135

1.05

0.00

10.9

4.5

0.0

estimate

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.85

0.00

4.8

4.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.98

0.00

1.1

1.7

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.0

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

240

1.00

0.00

8.0

5.2

0.0

estimate

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.2

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

5.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3004451) EKG impression Narrative

0.00

0.0

1.3

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal

0.00

0.0

1.2

—

1.2

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

80.4

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

0.0

1.6

—

2.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.2

—

15.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.4

—

(4146454)

0.00

0.0

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

180

1.00

0.00

8.4

4.3

—

(3012565) Volume of 24 hour Urine

0.00

0.0

2.1

—

1777.9

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(4062490)

0.00

0.0

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint J10_ABSCMEDIASTINUM and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
J10_ABSCMEDIASTINUM	2.669 [1.97, 3.61]	< 0.001
Birth year	0.985 [0.98, 0.99]	0.001

During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 240 males with J10_ABSCMEDIASTINUM died.

Mortality risk

Mortality risk for people of age

years, who have J10_ABSCMEDIASTINUM.

N-year risk	Females	Males
1	No data	0.478%
5	No data	3.176%
10	No data	7.433%
15	No data	13.659%
20	No data	21.813%

Relationships between endpoints

↥

Index endpoint: J10_ABSCMEDIASTINUM – Abscess of mediastinum

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Abscess of mediastinum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints