Abscess of mediastinum

J10_ABSCMEDIASTINUM

Lung Abscess: Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — J85.3 Hospital discharge: ICD-9 — 5131 Cause of death: ICD-10 — J85.3 Cause of death: ICD-9 — 5131 2 out of 7 registries used, show all original rules.	63
4. Check minimum number of events None	63
5. Include endpoints None	63
6. Filter based on genotype QC (FinnGen only)	63

Control definitions (FinnGen only)

Control exclude: J10_NECROTIC

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: J85
Name in latin: Abscessus mediastini

NAME	J10_ABSCMEDIASTINUM
CONTROL_EXCLUDE	J10_NECROTIC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J853
HD_ICD_9	5131
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J853
COD_ICD_9	5131
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Abscess of mediastinum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	468	143	320
Only index persons	353	110	243
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	62.93	66.74	61.28
Only index persons	61.87	64.58	60.65

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	63	22	41
Unadjusted period prevalence (%)	0.01	0.01	0.02
Median age at first event (years)	65.99	61.50	68.40

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
63: Matched controls
630

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

J85.3

ICD-10 Finland

Abscess of mediastinum

+∞

80.6

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

12.7

12.5

ZXD05

NOMESCO Finland

Urgent procedure

5.9

11.4

122

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

6.1

11.4

FWC00

NOMESCO Finland

Reoperation for deep infection in surgery of heart and major thoracic vessels

+∞

9.6

J98.5

ICD-10 Finland

Diseases of mediastinum, not elsewhere classified

58.4

9.0

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

9.6

8.8

ENA32

NOMESCO Finland

Incision of deep pharyngeal infection

+∞

8.5

N17.9

ICD-10 Finland

Acute renal failure, unspecified

14.5

7.4

J01FF01

ATC

clindamycin; systemic

4.1

6.8

GD1BD

NOMESCO Finland

Thorax extensive CT-examination

8.7

6.7

J01MA12

ATC

levofloxacin; systemic

4.2

6.6

TQW11

NOMESCO Finland

Vacuum treatment of wound

30.0

6.4

ZXE20

NOMESCO Finland

More than three and less than five hours

4.5

6.3

FNA01

NOMESCO Finland

Anastomosis to coronary artery from internal mammary artery, one distal anastamosis

7.5

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042936) Bacteria identified in Isolate by Culture

4.83

7.54

5.6

2.0

—

(3023368) Bacteria identified in Blood by Culture

154

3.86

6.56

9.3

5.0

—

(3024928) Oxygen saturation in Venous blood

14.70

5.78

2.7

2.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

108

3.63

5.68

6.5

2.3

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

3.69

5.29

12.5

5.8

1.19

1.10

mmol/l

0.35

(3019230) Fractional oxyhemoglobin in Venous blood

12.84

4.93

2.5

1.0

68.00

67.24

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

3.45

4.91

13.2

3.0

0.78

0.81

mmol/l

0.65

(3000991) Gas panel - Venous blood

3.86

4.59

19.8

7.5

—

(3044640) Blood type and Crossmatch panel - Blood

151

3.07

4.55

7.4

2.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

4.56

4.23

2.2

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

202

2.83

3.94

6.4

2.7

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

9.65

3.88

2.0

1.9

—

(3002032) Base excess in Venous blood by calculation

3.42

3.87

4.6

3.9

-0.34

1.78

mmol/l

0.87

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

5.10

3.84

2.4

2.8

0.85

1.46

1.04

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

5.10

3.84

2.4

2.8

0.67

0.78

0.37

(3005719) IgG [Mass/volume] in Serum or Plasma

3.64

3.61

2.6

2.9

9.80

10.09

g/l

0.09

(3000494) Fungus identified in Specimen by Culture

3.23

3.55

2.1

1.5

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

6.37

3.46

1.4

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

6.37

3.46

1.4

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.85

3.44

2.0

1.8

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.99

3.33

5.8

4.1

22.32

23.51

mmol/l

0.50

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

5.94

3.31

1.1

1.6

—

(3005570) Glucose [Moles/volume] in Urine

10.70

3.03

1.0

3.2

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

10.70

3.03

1.4

1.0

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

3.56

2.97

1.8

1.76

1.41

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.62

2.88

5.4

3.1

1380.35

235.11

ng/l

0.65

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.90

2.84

2.4

3.0

130.20

127.48

g/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.19

2.80

24.9

8.0

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

8.91

2.80

1.2

1.0

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

6.49

2.76

1.2

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

6.49

2.76

1.2

1.1

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

3.02

2.73

2.6

2.7

3.51

6.64

ug/l

1.24

(40760892) CBC W Ordered Manual Differential panel - Blood

250

2.31

2.62

14.5

6.6

—

(42529406) Shigella sp [Presence] in Stool by Culture

5.90

2.60

1.2

1.1

—

(3028026) IgM [Mass/volume] in Serum or Plasma

3.20

2.50

1.9

1.6

0.83

0.95

g/l

0.29

(3008757) Leukocyte morphology finding [Identifier] in Blood

6.67

2.41

1.4

2.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

4.24

2.32

1.1

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.95

2.28

7.5

1.9

207.45

211.08

ng/l

0.01

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.32

2.25

1.8

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.67

2.22

1.5

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.01

2.22

1.7

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.50

2.20

2.1

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.73

2.18

1.2

1.5

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

5.32

2.11

1.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.48

2.06

2.9

1.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.62

1.90

24.2

8.9

24.41

24.82

mmol/l

0.12

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

3.78

1.88

2.3

1.1

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

4.42

1.86

2.6

1.9

11.40

13.86

mg/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.24

1.85

2.3

2.4

2.60

0.61

e6/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

254

1.97

1.84

16.1

8.0

1.20

1.21

mmol/l

0.38

216

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.32

1.81

2.1

1.6

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.57

1.79

1.8

1.5

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

4.08

1.75

1.0

1.1

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

4.08

1.75

1.0

1.3

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

4.08

1.75

1.0

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

4.08

1.75

1.2

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

3.38

1.70

1.0

1.3

—

(3025941) Bacteria identified in Stool by Culture

3.02

1.70

1.3

1.2

—

(40768797) Stomach Pathology biopsy report

2.25

1.70

1.4

1.3

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

3.78

1.65

1.0

1.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

103

2.05

1.63

4.8

2.3

1.41

1.15

mg/l

0.32

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

3.20

1.62

2.5

2.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

254

1.85

1.56

24.4

16.0

1.49

1.31

inr

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

3.05

1.54

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

2.15

1.46

10.5

3.7

4.84

12.16

umol/l

1.39

(3022313) Gas panel - Capillary blood

2.33

1.40

11.6

7.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.10

1.38

1.6

1.4

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

3.10

1.38

1.4

1.2

—

(4035726) Immunohistochemistry procedure

2.29

1.36

2.3

1.4

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.29

1.36

1.8

4.1

61.82

66.40

g/l

—

(36304419) Bacteria [Presence] in Urine

143

1.83

1.36

3.0

2.9

—

(36660697) Celiac disease serology panel - Serum

2.54

1.35

1.5

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

198

1.75

1.30

2.7

2.1

103.73

92.77

pmol/l

0.66

110

(3018095) Leukocytes [#/volume] in Urine

191

1.72

1.24

3.5

4.0

28.30

47.83

e6/l

0.51

138

(3030467) Casts [#/volume] in Urine by Automated count

147

1.76

1.23

3.0

2.8

0.43

0.30

e6/l

0.14

110

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

2.14

1.17

13.1

7.9

23.00

25.13

mmol/l

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

231

1.67

1.16

13.0

4.9

31.87

35.05

g/l

1.93

218

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

290

1.67

1.14

5.4

3.2

70.13

48.20

u/l

0.76

271

(3037467) Urinalysis macro (dipstick) panel - Urine

322

1.66

1.09

6.1

4.2

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

2.38

1.05

1.0

6.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

1.00

0.0

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.97

0.98

11.6

11.2

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.35

0.96

2.5

2.4

—

(3020891) Body temperature

2.26

0.94

6.0

5.4

—

(3000492) Spirometry study

1.98

0.91

2.0

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.10

0.89

1.5

—

(3019225) pH of Specimen

1.89

0.88

6.6

4.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.03

0.87

1.2

1.3

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

2.03

0.87

1.3

3.2

—

55.00

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.84

0.86

7.1

3.3

24.62

29.21

u/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.80

0.0

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.79

0.0

1.7

—

(3002385) Erythrocyte distribution width [Ratio]

418

0.68

0.73

59.0

19.8

15.20

14.87

0.21

413

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

341

1.47

0.71

3.8

3.5

14.79

14.82

pmol/l

0.02

307

(3011397) Hemoglobin [Presence] in Urine by Test strip

113

1.56

0.70

9.0

4.0

—

(3019060) Gas panel - Arterial blood

1.70

0.69

5.3

3.6

—

(1761868) Lipid panel - Serum or Plasma

161

0.62

0.69

2.0

3.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.78

0.65

2.4

3.3

—

(3022145) Colonoscopy Study observation

1.62

0.62

1.5

1.4

—

(4034850) Laboratory test

0.00

0.61

0.0

21.0

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.59

0.0

2.6

—

123.94

—

(40758558) Short blood count panel - Blood

145

1.44

0.58

23.9

7.3

—

(3009343) pH of Capillary blood

1.58

0.58

11.8

6.4

—

7.40

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.55

0.57

11.9

6.3

5.06

5.11

kpa

—

(3015736) pH of Urine

193

1.39

0.55

7.0

3.8

—

5.73

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.59

0.53

16.5

4.5

276.70

257.29

u/l

—

(3002582) Erythrocytes [#/volume] in Urine

169

1.36

0.47

3.1

3.3

156.63

410.93

e6/l

0.28

131

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

278

1.31

0.42

2.7

2.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

178

0.73

0.42

3.2

4.2

22.38

21.61

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

6.1

—

32.92

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.2

—

0.77

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.40

0.0

3.1

—

14.80

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.35

0.39

1.2

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

194

1.29

0.37

4.3

3.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.44

0.36

2.2

3.9

—

(3002256) Pathology report gross observation

1.36

0.30

1.4

1.3

—

(3044889) 12 lead EKG panel

342

0.82

0.28

7.1

4.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

152

1.26

0.28

3.8

1.9

172.39

157.65

u/l

0.10

144

(3026008) Bacteria identified in Urine by Culture

143

1.26

0.27

3.3

2.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

154

1.24

0.25

3.7

3.8

26.55

9.32

mg/mmol

0.50

103

(40761535) Cells panel - Urine sediment

1.38

0.24

8.2

3.4

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.38

0.24

18.4

7.7

7.78

8.56

kpa

—

(3000963) Hemoglobin [Mass/volume] in Blood

523

0.79

0.24

63.6

23.9

121.30

134.14

g/l

4.65

511

(3024731) MCV [Entitic volume]

523

0.79

0.24

62.7

23.7

91.07

90.86

0.11

512

(3035941) MCH [Entitic mass]

523

0.79

0.24

62.6

23.7

30.02

30.23

0.36

512

(3035350) Ketones [Presence] in Urine by Test strip

242

1.20

0.24

6.5

4.0

0.00

estimate

—

(40761536) Microorganisms panel - Urine sediment

1.21

0.22

3.2

3.8

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.5

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

1.4

—

91.60

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

4.8

—

(40761511) CBC panel - Blood by Automated count

493

0.82

0.21

36.4

15.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.21

0.0

1.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(40768804) Tissue Pathology biopsy report

186

1.19

0.20

3.5

2.1

—

(40768800) Prostate Pathology biopsy report

0.00

0.20

0.0

1.1

—

(3003694) ABO and Rh group [Type] in Blood

111

1.22

0.17

2.7

1.3

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

496

0.86

0.12

53.7

19.3

3.96

4.02

mmol/l

0.72

483

(3031040) Bacteria [#/volume] in Urine by Automated count

313

1.11

0.11

7.0

4.5

—

436.22

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.82

0.08

1.8

1.6

449.80

355.81

nmol/l

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

0.79

0.08

1.2

—

14.80

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

493

0.89

0.08

51.9

19.4

138.83

139.60

mmol/l

1.22

479

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.09

0.08

1.1

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

129

0.91

0.04

2.4

3.8

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

498

0.93

0.03

26.8

11.2

29.71

25.78

u/l

0.33

480

(3020564) Creatinine [Moles/volume] in Serum or Plasma

497

0.94

0.02

49.7

19.3

83.63

82.65

umol/l

0.05

497

(3021601) Nitrite [Presence] in Urine by Test strip

243

1.05

0.01

7.8

5.2

0.00

estimate

—

(3013512) EKG study

144

1.05

0.00

5.2

4.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

434

1.05

0.00

5.2

4.3

2.46

2.05

mu/l

0.72

384

(3012516) Albumin [Mass/volume] in Urine

147

1.03

0.00

3.0

3.2

85.83

61.39

mg/l

—

102

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

184

0.97

0.00

8.4

4.3

—

(3029937) Albumin [Presence] in Urine by Test strip

138

1.02

0.00

10.9

4.4

0.00

estimate

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

247.67

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

1.7

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3004451) EKG impression Narrative

0.00

0.0

1.3

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.2

—

15.62

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.3

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.4

—

(3045424) Erythrocytes [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

80.44

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.6

—

2.22

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

-0.00

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.02

-0.00

4.5

4.2

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

2.1

—

1777.86

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.4

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint J10_ABSCMEDIASTINUM and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
J10_ABSCMEDIASTINUM	2.669 [1.97, 3.61]	< 0.001
Birth year	0.985 [0.98, 0.99]	0.001

During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 240 males with J10_ABSCMEDIASTINUM died.

Mortality risk

Mortality risk for people of age

years, who have J10_ABSCMEDIASTINUM.

N-year risk	Females	Males
1	No data	0.478%
5	No data	3.176%
10	No data	7.433%
15	No data	13.659%
20	No data	21.813%

Relationships between endpoints

↥

Index endpoint: J10_ABSCMEDIASTINUM – Abscess of mediastinum

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Abscess of mediastinum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints