No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
561 |
4. Check minimum number of eventsNone |
561 |
5. Include endpointsNone |
561 |
6. Filter based on genotype QC (FinnGen only) |
561 |
Control definitions (FinnGen only)
- Control exclude
- AB1_OTHER_BACTERIAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Infection due to other mycobacteria
based on the number of shared cases.
Similar with more cases:
- Other bacterial diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4384 | 2364 | 1935 |
| Only index persons | 2970 | 1735 | 1235 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.05 |
| Only index persons | 0.06 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 67.61 | 68.82 | 66.10 |
| Only index persons | 66.78 | 68.03 | 65.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 561 | 293 | 268 |
| Unadjusted period prevalence (%) | 0.11 | 0.10 | 0.12 |
| Median age at first event (years) | 65.02 | 63.21 | 67.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 490
- Matched controls
- 4899
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
+∞
323.0
328
*
J47
ICD-10 Finland
Bronchiectasis
65.1
113.5
130
27
UGC12
NOMESCO Finland
Flexible bronchoscopy
15.8
107.8
191
190
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
+∞
105.1
97
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
20.9
96.0
148
99
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
11.3
92.0
195
271
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.9
79.8
265
717
R03BB04
ATC
tiotropium bromide; inhalant
8.7
71.9
176
296
J01MA12
ATC
levofloxacin; systemic
6.5
63.1
197
458
J01MA14
ATC
moxifloxacin; systemic
10.1
62.2
134
176
A49.9
ICD-10 Finland
Bacterial infection, unspecified
71.5
60.2
68
11
R03AK06
ATC
salmeterol and fluticasone; inhalant
6.6
58.0
174
377
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
5.6
57.5
208
568
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
20.6
56.7
86
50
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.5
53.4
318
1428
TGC00
NOMESCO Finland
Bronchial lavation
19.5
50.6
78
47
A31.89
ICD-10 Finland
Other mycobacterial infections
+∞
45.5
43
*
A31.1
ICD-10 Finland
Cutaneous mycobacterial infection
+∞
44.5
42
*
R03AC02
ATC
salbutamol; inhalant
3.9
44.2
336
1745
J45.9
ICD-10 Finland
Asthma, unspecified
5.0
44.2
167
455
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
9.4
43.3
94
120
GD1AD
NOMESCO Finland
Thorax CT examination
13.0
41.9
76
68
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.6
40.2
303
1507
H02AB06
ATC
prednisolone; systemic
3.6
40.2
305
1528
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
6.5
39.9
114
219
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
5.2
38.0
133
326
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
+∞
33.7
32
*
R03DA04
ATC
theophylline; systemic, rectal
6.4
33.3
94
175
R03AC12
ATC
salmeterol; inhalant
7.5
31.7
79
123
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
7.5
29.9
74
114
R03DC03
ATC
montelukast; oral
4.3
29.8
127
371
J01FA06
ATC
roxithromycin; oral
3.0
29.1
260
1341
J45.0
ICD-10 Finland
Predominantly allergic asthma
5.7
28.7
88
180
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.8
28.2
139
460
R04.2
ICD-10 Finland
Haemoptysis
8.6
28.1
63
83
R03BA05
ATC
fluticasone; inhalant
3.6
26.2
137
471
J45.1
ICD-10 Finland
Nonallergic asthma
5.6
25.4
78
159
R50.9
ICD-10 Finland
Fever, unspecified
4.3
25.0
101
277
H02AB04
ATC
methylprednisolone; systemic
3.7
24.9
125
415
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.0
24.6
71
134
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
59.2
24.3
28
5
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
7.9
23.0
54
76
R03AC03
ATC
terbutaline; inhalant
3.6
22.8
117
393
H02AB07
ATC
prednisone; oral
3.5
22.7
120
410
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
12.7
22.4
40
34
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.7
22.0
52
74
J01AA02
ATC
doxycycline; systemic
3.0
21.5
406
3027
XG410
NOMESCO Finland
Flow-volume spirometry
7.2
20.6
51
78
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
4.5
20.3
76
191
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
20.2
111
390
R03BB01
ATC
ipratropium bromide; inhalant
5.8
20.1
59
113
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
19.9
19
*
R03BA02
ATC
budesonide; inhalant
3.1
19.4
125
491
A02BC02
ATC
pantoprazole; systemic
2.4
18.3
334
2312
A46
ICD-10 Finland
Erysipelas
5.7
18.0
53
102
J01FA09
ATC
clarithromycin; systemic
2.5
17.8
180
923
R03BA01
ATC
beclometasone; inhalant
3.2
17.6
105
387
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
17.6
208
1153
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
17.3
88
290
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.9
17.2
58
131
J96.1
ICD-10 Finland
Chronic respiratory failure
8.7
16.8
36
44
R03AC13
ATC
formoterol; inhalant
5.2
16.8
53
111
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.3
16.7
52
107
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
93.3
16.7
18
*
R03AK08
ATC
formoterol and beclometasone; inhalant
6.1
16.3
45
80
J46
ICD-10 Finland
Status asthmaticus
8.3
15.9
35
45
A31.80
ICD-10 Finland
Oral infection caused by Mycobacterium intracellulare
+∞
15.7
15
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
7.0
15.4
38
58
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.6
15.3
54
128
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.4
15.0
158
813
J01MA02
ATC
ciprofloxacin; systemic
2.2
14.4
210
1253
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.2
14.1
38
66
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.8
14.0
61
176
N02AA05
ATC
oxycodone; systemic
2.9
14.0
91
354
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
12.6
13.7
24
20
03199
ICD-8 Finland
Other diseases due to Mycobacteria, Other and unspecified
+∞
13.6
13
*
R03BA08
ATC
ciclesonide; inhalant
3.9
13.5
57
160
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
13.4
166
914
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
7.9
13.4
30
40
J01FA10
ATC
azithromycin; systemic
2.1
13.3
266
1796
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.1
13.2
42
89
N02AX02
ATC
tramadol; systemic, rectal
2.1
13.1
222
1398
R02
ICPC
Shortness of breath/dyspnoea
2.9
12.8
81
309
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
10.5
12.6
24
24
R05
ICD-10 Finland
Cough
2.5
12.6
113
528
J01GB01
ATC
tobramycin; inhalant, parenteral
+∞
12.5
12
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
133.3
12.5
13
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.5
12.4
44
105
J02AC01
ATC
fluconazole; systemic
2.1
12.4
191
1149
R03AK11
ATC
formoterol and fluticasone; inhalant
8.1
12.3
27
35
R03AK07
ATC
formoterol and budesonide; inhalant
2.5
12.3
106
484
SPAT1255
SPAT
Intravenous administration of medicine
4.3
12.0
45
113
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.1
12.0
181
1076
WW200
NOMESCO Finland
Immunization
6.6
11.9
30
48
SPAT1017
SPAT
Examination of colour vision
66.6
11.7
13
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.8
11.5
32
58
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
11.5
60
200
R81
ICPC
Pneumonia
5.2
11.5
35
71
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
122.8
11.5
12
*
J01CA04
ATC
amoxicillin; systemic
2.1
11.4
375
2991
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
35.9
11.3
14
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
11.3
53
163
R06.0
ICD-10 Finland
Dyspnoea
2.2
11.2
142
779
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
12.3
10.9
19
16
A07AA02
ATC
nystatin; oral
3.5
10.9
51
157
J45
ICD-10 Finland
Asthma
3.0
10.8
63
227
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.5
10.7
51
159
A03
ICPC
Fever
2.7
10.6
75
303
J45.8
ICD-10 Finland
Mixed asthma
5.4
10.5
31
61
J02AC03
ATC
voriconazole; systemic
112.3
10.5
11
*
1240
FHL
Bronchoscopy
8.5
10.4
22
27
M05BA04
ATC
alendronic acid; oral
2.8
10.4
68
264
R01AD08
ATC
fluticasone; nasal
2.1
10.4
138
769
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.4
10.2
50
159
C03CA01
ATC
furosemide; systemic
2.0
10.1
171
1045
JN4AD
NOMESCO Finland
Body CT examination
3.4
10.1
50
160
R03BB02
ATC
oxitropium bromide; inhalant
11.6
10.1
18
16
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
10.4
10.1
19
19
R05
ICPC
Cough
2.2
10.0
116
607
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
40.9
10.0
12
*
JN4BD
NOMESCO Finland
Extensive body CT
2.7
10.0
69
277
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.0
10.0
31
65
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.9
9.9
18
17
R03DC01
ATC
zafirlukast; oral
7.6
9.8
22
30
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.9
9.7
39
106
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.5
9.7
45
138
R01AD09
ATC
mometasone; nasal
1.9
9.6
203
1343
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.8
9.5
23
35
L04AD01
ATC
ciclosporin; systemic
7.8
9.5
21
28
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.1
9.4
22
32
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
9.4
9
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
4.8
9.4
30
65
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
9.3
97
484
L04AX01
ATC
azathioprine; systemic
4.9
9.2
29
62
A01AB04
ATC
amphotericin B; local oral
3.4
9.0
44
140
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
7.7
9.0
20
27
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
8.9
63
257
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
8.8
106
560
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.8
8.7
36
100
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.7
8.4
23
42
XQ800
NOMESCO Finland
Prick test
3.3
8.4
42
137
B44.8
ICD-10 Finland
Other forms of aspergillosis
+∞
8.4
8
*
127
Kela drug reimbursment
Transplant complication
9.7
8.3
16
17
L04AA06
ATC
mycophenolic acid; systemic
7.3
8.3
19
27
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.6
8.2
23
43
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
8.3
8.1
17
21
A01AB09
ATC
miconazole; local oral
2.8
8.1
54
210
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
17.5
8.1
12
7
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
33.9
8.1
10
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.3
8.1
39
124
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
8.0
89
457
P01BA02
ATC
hydroxychloroquine; oral
2.9
7.9
49
182
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
8.7
7.9
16
19
C07AB07
ATC
bisoprolol; oral
1.7
7.9
238
1735
A03FA01
ATC
metoclopramide; systemic, rectal
2.0
7.8
106
588
L04AA01
ATC
[U] ciclosporin; systemic
7.6
7.7
17
23
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
7.7
98
529
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
7.7
61
265
NF1AA
NOMESCO Finland
Hip X-ray examination
2.6
7.4
54
223
WX892
NOMESCO Finland
Monitored bed care
2.8
7.4
46
172
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
7.4
108
616
J20
ICD-10 Finland
Acute bronchitis
2.6
7.4
53
217
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
+∞
7.3
7
*
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
+∞
7.3
7
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
7.3
7
*
49300
ICD-8 Finland
Asthma, bronchiale
4.8
7.3
23
50
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.8
7.3
23
50
B03XA02
ATC
darbepoetin alfa; parenteral
7.5
7.2
16
22
R05CB01
ATC
acetylcysteine; inhalant, oral
5.4
7.2
20
38
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
7.1
30
86
A02BA02
ATC
ranitidine; systemic
1.9
7.0
114
678
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.8
7.0
126
775
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.2
6.9
35
116
R24
ICPC
Haemoptysis
14.0
6.9
11
8
J01FF01
ATC
clindamycin; systemic
1.8
6.9
127
787
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
5.2
6.9
20
40
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
6.8
51
215
J01FA15
ATC
telithromycin; oral
2.5
6.8
51
215
WZC30
NOMESCO Finland
Teaching
2.3
6.8
66
316
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
6.2
6.8
17
28
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
4.8
6.8
21
45
XG466
NOMESCO Finland
Sleep oxymetry
4.1
6.8
25
64
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
40.6
6.8
8
*
J15.8
ICD-10 Finland
Other bacterial pneumonia
17.0
6.8
10
6
J86.9
ICD-10 Finland
Pyothorax without fistula
17.0
6.8
10
6
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
6.7
100
572
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.6
6.6
49
204
348
Kela drug reimbursment
Roflumilast
12.5
6.6
11
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.5
6.5
18
34
R96
ICPC
Asthma
2.5
6.5
49
209
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
70.7
6.4
7
*
R03DX07
ATC
roflumilast; oral
14.5
6.4
10
7
R4190
NOMESCO Finland
Nutritional therapy
4.3
6.4
22
53
A02BC05
ATC
esomeprazole; systemic
1.7
6.4
184
1301
N03AX16
ATC
pregabalin; oral
1.8
6.4
109
657
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
6.3
28
85
A07EC02
ATC
mesalazine; oral, rectal
3.4
6.3
28
85
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
+∞
6.3
6
*
304
Kela drug reimbursment
Dornase alfa
+∞
6.3
6
*
NDS99
NOMESCO Finland
Other operation for infection of tendon, joint or bone of wrist or hand
+∞
6.3
6
*
B96.5
ICD-10 Finland
Pseudomonas (aeruginosa) as the cause of diseases classified to other chapters
+∞
6.3
6
*
B05XA03
ATC
sodium chloride; parenteral
+∞
6.3
6
*
L88
ICPC
Rheumatoid/seropositive arthritis
4.0
6.2
23
60
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.8
6.1
12
14
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
8.8
6.1
12
14
J01DA01
ATC
[U] cefalexin; systemic
1.6
6.0
281
2240
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
215
129
26.40
273.21
9.0
2.8
—
—
—
0
0
114
45
31.54
167.94
12.9
3.5
—
—
—
0
0
70
14
56.99
122.83
14.7
3.0
—
—
—
0
0
114
89
15.82
122.37
2.9
1.3
—
—
—
0
0
83
39
24.80
113.49
1.8
1.4
—
—
—
0
0
89
51
20.55
111.71
1.8
1.4
—
—
—
0
0
70
25
31.85
105.50
2.0
1.0
1.6
0.0
u/ml
1.36
52
13
70
36
22.07
91.79
1.6
1.4
—
—
—
0
0
72
41
20.00
90.20
1.6
1.4
—
—
—
0
0
145
276
6.74
76.95
3.0
2.3
10.4
10.6
g/l
0.18
138
245
72
56
14.60
76.49
1.3
1.1
—
—
—
0
0
58
30
21.45
75.58
2.0
1.5
—
—
—
0
0
76
76
11.41
68.77
2.2
1.4
—
—
—
0
0
64
0
+∞
68.13
2.8
0.0
—
—
—
0
0
73
74
11.19
65.37
2.3
1.4
—
—
—
0
0
47
24
21.28
61.36
2.8
1.8
2503.8
662.1
e6/l
—
28
8
62
54
12.78
61.26
2.4
1.4
—
—
—
0
0
116
221
6.36
60.71
2.0
1.2
162.1
281.9
u/ml
0.53
109
205
201
665
4.15
53.63
3.0
1.7
—
—
—
0
0
36
18
21.30
47.20
1.6
1.0
—
—
—
0
0
32
13
26.04
45.44
3.3
2.6
—
—
—
0
0
43
35
13.22
44.02
2.4
1.3
—
—
—
0
0
33
16
21.85
43.76
3.1
2.3
17.4
13.3
%
—
16
9
30
13
24.32
41.53
1.9
1.1
—
—
—
0
0
28
11
26.74
40.13
1.9
1.1
—
—
—
0
0
28
11
26.74
40.13
1.9
1.1
—
—
—
0
0
101
256
4.59
37.38
1.9
1.4
—
—
—
0
0
393
2371
3.20
35.54
19.9
7.3
4.7
4.1
e9/l
4.99
380
2061
42
46
9.79
35.19
2.4
1.3
—
—
—
0
0
166
649
3.21
32.22
7.1
2.6
0.8
0.8
mmol/l
0.22
157
602
50
83
6.52
29.41
2.0
1.5
—
—
—
0
0
25
16
16.31
28.99
2.0
1.3
—
—
—
0
0
25
16
16.31
28.99
2.0
1.3
—
—
—
0
0
25
16
16.31
28.99
2.0
1.3
—
—
—
0
0
25
16
16.31
28.99
2.0
1.3
—
—
—
0
0
33
35
9.96
28.21
2.3
1.6
—
—
—
0
0
43
64
7.19
27.99
5.4
2.7
5.0
4.0
e9/l
1.62
43
64
88
249
4.01
27.81
6.3
3.1
1.7
2.1
mmol/l
0.40
71
187
53
100
5.75
27.37
2.0
1.5
0.3
0.2
iu/ml
0.25
13
18
127
464
3.25
27.18
2.5
1.7
—
—
—
0
0
33
37
9.41
27.08
2.3
1.6
—
—
—
0
0
43
69
6.67
26.09
5.5
2.8
61.6
56.6
%
1.81
43
69
20
10
20.70
25.89
2.2
1.4
—
—
—
0
0
20
10
20.70
25.89
2.2
1.4
—
—
—
0
0
20
10
20.70
25.89
2.3
1.4
—
—
—
0
0
30
32
9.85
25.51
2.0
1.5
—
—
—
0
0
30
32
9.85
25.51
2.0
1.5
—
—
—
0
0
30
32
9.85
25.51
2.0
1.5
—
—
—
0
0
124
464
3.15
25.36
2.6
1.8
—
—
—
0
0
27
25
11.30
25.28
1.9
1.1
—
—
—
0
0
67
167
4.42
25.00
3.6
1.5
—
—
—
0
0
62
154
4.40
23.20
2.9
1.5
—
—
—
0
0
348
2244
2.45
22.98
14.0
5.0
8.9
10.9
umol/l
10.66
340
2106
28
8
36.73
22.25
1.5
1.1
—
—
—
0
0
340
2217
2.35
21.19
12.2
5.5
1.2
1.2
mmol/l
0.65
281
1854
41
79
5.52
20.63
1.7
1.3
—
—
—
0
0
41
79
5.52
20.63
1.7
1.3
—
—
—
0
0
314
2025
2.25
19.47
10.3
5.0
1.2
1.2
mmol/l
0.01
299
1801
17
14
12.49
16.98
1.9
2.4
800.8
630.5
u/ml
0.23
17
14
34
69
5.18
16.14
2.6
1.6
—
—
—
0
0
35
76
4.85
15.38
2.9
2.1
15.9
16.4
%
0.28
19
40
285
1911
2.00
14.38
7.3
3.8
32.9
35.8
g/l
11.29
265
1768
414
3178
2.16
14.23
11.6
3.9
19.0
12.1
mm/h
11.46
402
2875
35
82
4.49
14.03
2.4
2.0
124.7
129.9
g/l
0.51
24
61
68
250
2.96
13.97
2.3
1.7
—
—
—
0
0
87
368
2.61
13.69
1.5
2.4
64.6
66.8
g/l
1.45
75
323
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
42
118
3.77
13.23
3.5
2.7
0.4
0.4
u/ml
0.05
25
71
61
221
2.97
12.84
6.4
9.2
25.0
24.8
mmol/l
0.10
53
200
183
1084
2.02
12.80
2.8
2.1
3.3
3.2
mg/l
0.21
165
897
125
642
2.22
12.71
3.4
2.1
11.3
12.8
umol/l
1.65
118
580
113
577
2.20
11.57
3.5
2.2
2.2
2.3
g/l
1.19
104
526
20
34
6.06
11.40
1.1
1.0
—
—
—
0
0
16
8
20.53
11.18
1.4
1.3
—
—
—
0
0
109
556
2.19
11.17
3.7
2.2
18.5
22.2
%
2.81
94
470
248
1709
1.81
10.45
3.6
2.6
133.8
120.7
ug/l
0.50
235
1528
23
49
4.85
10.32
1.4
1.3
111.4
106.8
u/ml
—
10
8
103
530
2.16
10.27
12.4
3.9
1.0
1.0
mmol/l
0.03
96
472
30
80
3.91
10.17
1.4
1.3
—
—
—
0
0
13
6
22.13
9.38
1.1
1.0
—
—
—
0
0
13
6
22.13
9.38
1.1
1.0
92.8
94.5
%
—
13
6
72
334
2.33
9.19
16.0
5.2
9.7
10.0
mmol/l
0.16
67
316
92
474
2.13
9.09
6.6
6.9
1.6
1.2
mmol/l
0.33
79
367
22
51
4.45
8.94
1.3
1.2
—
—
—
0
0
43
157
2.88
8.92
1.6
2.1
3.6
3.1
g/l
1.68
31
118
29
83
3.63
8.91
1.2
1.1
—
—
—
0
0
13
18
7.37
8.88
13.7
6.6
51.1
37.8
u/ml
—
7
5
45
169
2.81
8.87
1.6
2.0
3.7
3.8
g/l
0.14
31
116
45
169
2.81
8.87
1.6
2.0
—
—
—
0
0
45
169
2.81
8.87
1.6
2.0
7.9
7.4
g/l
0.78
33
119
408
3343
1.81
8.79
19.8
6.3
80.5
77.3
u/l
0.79
403
3095
298
2243
1.70
8.66
3.2
2.6
—
—
—
0
0
327
2527
1.70
8.58
7.9
4.2
6.4
6.7
mmol/l
1.59
318
2350
12
6
20.39
8.50
2.7
1.2
—
—
—
0
0
74
359
2.22
8.49
2.0
1.8
293.8
368.6
nmol/l
2.69
68
322
184
1224
1.75
8.32
5.7
3.0
0.2
0.4
e6/l
2.18
160
924
76
378
2.17
8.19
8.1
2.6
2.7
1.9
mmol/l
0.91
66
305
35
120
3.04
8.11
1.5
1.1
—
—
—
0
0
137
846
1.82
7.93
3.1
1.6
1.8
1.3
mg/l
0.40
114
647
21
52
4.16
7.87
2.0
1.7
89.3
89.5
%
0.05
21
52
203
1413
1.68
7.67
4.3
2.9
1594.8
1377.7
ng/l
0.27
184
1201
50
214
2.47
7.62
1.6
1.3
—
—
—
0
0
21
55
3.93
7.31
1.8
1.3
—
—
—
0
0
17
38
4.58
7.22
4.8
2.4
—
—
—
0
0
37
140
2.76
7.21
1.4
3.7
194.8
98.1
mg/l
0.34
29
111
11
16
6.99
7.17
1.6
1.3
—
—
—
0
0
11
16
6.99
7.17
1.6
1.3
—
—
—
0
0
21
56
3.86
7.14
1.8
1.3
—
—
—
0
0
21
56
3.86
7.14
1.8
1.3
—
—
—
0
0
37
141
2.74
7.12
1.4
3.7
43.4
41.5
mg/l
0.04
30
113
43
177
2.55
7.11
2.2
1.8
1.6
1.6
g/l
0.07
37
150
17
40
4.35
6.79
2.2
1.3
58.4
66.7
%
0.31
12
28
17
40
4.35
6.79
1.1
1.1
1.5
1.5
g/l
0.09
17
34
37
145
2.66
6.75
1.7
2.4
0.6
1.0
g/l
0.39
31
120
39
158
2.58
6.67
1.6
2.1
9.9
10.3
g/l
0.22
31
129
212
1539
1.61
6.56
5.1
3.0
2.3
2.4
mmol/l
1.39
191
1313
11
18
6.21
6.45
1.8
1.2
53.1
14.2
u/l
0.76
11
13
20
56
3.67
6.37
1.8
1.3
—
—
—
0
0
20
56
3.67
6.37
1.8
1.3
—
—
—
0
0
109
672
1.77
6.23
1.3
1.3
76.1
38.6
iu/ml
0.57
40
211
20
57
3.60
6.21
1.8
1.3
—
—
—
0
0
70
376
1.98
6.13
3.3
2.9
142.8
203.2
ng/l
1.35
64
336
11
19
5.89
6.13
1.6
1.4
—
—
—
0
0
19
53
3.68
6.08
1.6
1.3
—
—
—
0
0
10
16
6.35
5.97
4.7
1.6
24.3
30.0
umol/l
—
10
16
209
1560
1.54
5.52
5.9
3.0
—
—
—
0
0
10
18
5.64
5.34
1.9
1.2
158.0
70.8
u/l
—
10
13
380
4293
0.64
5.33
5.4
5.2
2.6
2.7
mmol/l
1.17
344
3870
185
1355
1.55
5.28
3.2
2.1
55.9
58.8
u/l
0.57
177
1238
75
439
1.82
5.07
5.7
3.0
—
—
—
0
0
10
19
5.34
5.05
1.7
1.4
—
—
—
0
0
130
892
1.60
4.88
1.9
1.8
1352.2
1174.5
nmol/l
1.23
96
635
231
1798
1.48
4.85
2.9
2.2
81.6
79.2
nmol/l
0.67
210
1552
8
7
11.57
4.79
1.3
1.1
—
—
—
0
0
24
92
2.68
4.62
1.8
1.3
—
—
—
0
0
10
21
4.83
4.54
1.3
1.0
—
—
—
0
0
63
362
1.83
4.52
10.7
6.4
1.3
1.4
mmol/l
0.13
57
344
110
739
1.61
4.49
4.5
2.7
0.6
1.1
e6/l
3.00
77
433
373
4187
0.67
4.46
5.0
4.6
4.6
4.6
mmol/l
0.18
334
3788
12
30
4.07
4.45
1.3
1.1
—
—
—
0
0
31
138
2.32
4.40
1.7
2.0
33.2
37.6
g/l
2.07
26
111
220
1728
1.45
4.27
6.1
3.5
83.0
63.5
ng/l
0.18
172
1278
371
4153
0.69
4.16
4.9
4.5
1.6
1.5
mmol/l
2.86
334
3734
141
1025
1.50
4.02
4.7
2.5
7802.3
8663.6
umol/l
0.05
132
852
64
386
1.74
3.92
2.3
2.1
30.9
32.5
u/l
0.18
56
328
152
1137
1.46
3.73
1.6
1.5
19.1
21.0
nmol/l
0.91
134
941
139
1028
1.47
3.61
3.8
2.2
—
—
—
0
0
15
51
2.99
3.60
1.1
1.1
—
—
—
0
0
377
4173
0.71
3.56
5.3
4.8
5.8
6.0
mmol/l
1.06
343
3701
88
600
1.55
3.35
35.2
24.5
1.5
1.2
inr
0.56
15
79
16
59
2.76
3.35
4.1
2.2
27.0
25.8
mg/l
—
6
18
69
444
1.63
3.34
2.7
2.1
6.2
7.0
umol/l
0.27
63
387
23
102
2.31
3.33
1.9
1.5
—
—
—
0
0
14
49
2.90
3.21
1.6
1.2
1.4
1.5
u/ml
—
5
15
13
44
3.00
3.15
1.4
1.1
263.1
309.6
pmol/l
—
8
35
361
3997
0.73
3.13
4.4
4.1
1.2
1.3
mmol/l
2.83
319
3565
7
12
5.89
3.03
1.4
1.1
-0.7
3.1
mmol/l
—
7
12
5
5
10.07
2.98
1.0
1.0
—
—
—
0
0
5
5
10.07
2.98
1.2
1.2
—
—
—
0
0
115
853
1.44
2.90
1.2
1.3
1.1
1.4
u/ml
0.29
21
208
115
854
1.44
2.88
4.8
3.6
986.3
326.5
ng/l
0.60
94
693
120
906
1.41
2.74
3.3
2.7
2.5
2.5
mmol/l
2.08
105
796
228
1906
1.33
2.74
2.1
2.0
93.6
95.9
pmol/l
0.33
136
953
13
48
2.75
2.73
1.5
1.1
—
—
—
0
0
95
688
1.46
2.72
5.4
2.9
1.6
2.6
e6/l
0.98
63
384
24
119
2.06
2.70
1.5
1.4
217.3
303.3
ug/g
1.01
12
67
10
32
3.16
2.66
1.4
1.2
—
—
—
0
0
10
32
3.16
2.66
1.4
1.2
—
—
—
0
0
15
62
2.46
2.56
1.1
1.1
—
—
—
0
0
18
82
2.23
2.50
1.3
1.2
—
—
—
0
0
9
26
3.50
2.49
1.0
1.2
—
—
—
0
0
7
16
4.42
2.48
3.9
1.4
79.5
58.9
ug/l
—
7
16
10
34
2.98
2.42
2.9
3.2
—
—
—
0
0
6
12
5.04
2.40
1.2
1.4
—
—
—
0
0
368
4009
0.76
2.38
5.9
5.9
39.4
40.0
mmol/mol
0.66
342
3654
167
1361
1.32
2.33
3.1
2.0
118.6
214.4
u/l
2.65
160
1261
32
187
1.75
2.26
1.7
1.3
—
—
—
0
0
7
18
3.92
2.26
1.3
1.3
—
—
—
0
0
74
533
1.45
2.19
13.8
6.0
103.8
104.3
mmol/l
0.44
74
521
19
94
2.06
2.18
2.1
1.3
—
—
—
0
0
87
648
1.41
2.15
1.3
1.3
18.5
11.8
u/ml
0.22
21
253
23
124
1.89
2.10
2.7
1.8
—
—
—
0
0
59
410
1.49
2.10
3.0
2.5
8.7
7.5
ug/l
0.23
47
352
9
31
2.93
2.08
1.6
2.6
—
—
—
0
0
6
15
4.03
2.04
1.2
1.2
—
—
—
0
0
9
32
2.84
2.01
1.4
1.3
—
—
—
0
0
5
11
4.58
1.94
10.4
2.9
—
—
—
0
0
292
2606
1.25
1.89
6.4
2.8
51.9
45.5
u/l
0.69
277
2389
9
34
2.67
1.87
1.7
1.4
—
—
—
0
0
23
132
1.77
1.76
1.4
1.2
—
—
—
0
0
6
18
3.36
1.75
1.2
1.1
57.2
62.2
u/l
—
6
11
6
18
3.36
1.75
1.2
1.1
6.3
10.4
u/l
—
6
11
6
18
3.36
1.75
2.7
2.6
—
—
—
0
0
23
133
1.76
1.72
1.4
1.2
—
—
—
0
0
10
42
2.41
1.68
1.5
1.6
—
—
—
0
0
73
949
0.73
1.68
6.6
4.2
1.0
1.0
kg/l
0.48
19
137
6
19
3.18
1.66
2.2
1.5
—
—
—
0
0
92
1153
0.76
1.65
4.3
4.5
20.4
21.5
%
0.28
46
581
49
346
1.46
1.64
4.0
2.5
70.9
62.7
ml/min/173m2
0.77
24
145
18
98
1.86
1.63
2.7
2.6
129.6
105.0
ug/min
—
9
58
117
1414
0.78
1.58
5.3
3.8
13.9
8.4
mg/mmol
0.50
85
864
21
122
1.75
1.56
2.0
1.5
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
117
1390
0.80
1.35
4.2
3.0
5.8
7.3
mmol/l
5.26
108
1142
6
24
2.52
1.30
1.5
1.5
—
—
—
0
0
6
24
2.52
1.30
1.5
1.5
—
—
—
0
0
443
4222
1.23
1.24
42.7
12.5
23.1
23.0
mg/l
0.02
418
3274
114
957
1.24
1.23
1.7
1.7
474.5
7864149.7
pmol/l
0.50
94
763
221
1986
1.19
1.18
5.7
3.8
—
—
—
0
0
345
3222
1.18
1.16
4.3
3.9
15.0
14.9
pmol/l
0.27
313
2869
46
601
0.74
1.12
13.4
6.8
—
—
—
0
0
15
89
1.70
1.08
1.9
1.2
—
—
—
0
0
19
278
0.67
0.92
1.6
1.7
—
—
—
0
0
6
28
2.15
0.91
1.3
1.0
—
—
—
0
0
70
578
1.24
0.90
1.4
1.4
—
—
—
0
0
13
79
1.66
0.88
1.1
1.3
—
43.4
—
0
10
28
206
1.38
0.83
3.2
2.6
26.4
25.1
mmol/l
0.90
28
201
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
228
2109
1.14
0.77
5.9
3.8
0.0
0.0
estimate
0.50
70
385
16
107
1.51
0.77
1.1
1.3
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
224
2076
1.13
0.73
5.9
3.7
0.0
0.0
estimate
0.00
66
396
129
1438
0.87
0.73
5.5
5.2
2.9
3.0
ug/l
0.08
113
1263
225
2090
1.13
0.70
7.9
5.0
0.0
0.0
estimate
0.00
71
391
15
104
1.45
0.63
1.3
1.2
—
—
—
0
0
7
112
0.62
0.58
1.7
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
2.1
—
48.4
—
0
17
74
834
0.87
0.50
3.4
3.2
0.9
0.8
ug/l
0.08
58
558
7
48
1.46
0.47
2.3
1.3
—
—
—
0
0
25
202
1.25
0.44
14.0
2.1
1.0
1.3
%
0.89
25
202
443
4524
0.90
0.43
25.2
9.6
23.0
24.9
u/l
2.52
438
4306
153
1636
0.91
0.43
6.8
4.0
—
—
—
0
0
6
94
0.63
0.42
1.3
1.4
—
—
—
0
0
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
126
1175
1.09
0.36
1.7
1.6
1.2
1.3
mmol/l
0.71
106
964
6
42
1.43
0.35
1.2
1.0
—
—
—
0
0
24
200
1.21
0.34
1.0
1.0
—
—
—
0
0
12
91
1.33
0.34
1.7
1.7
—
—
—
0
0
6
45
1.34
0.34
1.2
1.0
—
—
—
0
0
7
57
1.23
0.29
1.0
1.0
—
—
—
0
0
124
1170
1.08
0.28
6.8
4.0
0.0
0.0
estimate
0.50
66
384
63
579
1.10
0.26
4.3
4.7
35.6
32.5
%
1.38
51
354
6
82
0.73
0.24
1.7
1.5
—
—
—
0
0
30
265
1.14
0.24
2.6
2.6
—
16.1
—
0
11
0
10
0.00
0.21
0.0
1.1
—
0.9
—
0
5
17
198
0.85
0.21
5.5
2.8
38.5
48.4
u/ml
0.19
17
189
6
48
1.25
0.20
5.7
2.7
29.5
59.0
u/ml
—
6
48
7
61
1.15
0.17
1.3
1.6
—
—
—
0
0
26
237
1.10
0.14
1.4
1.4
—
42.8
—
0
17
14
125
1.12
0.10
4.1
3.4
3.8
4.0
mmol/l
1.48
14
118
404
4016
1.02
0.06
31.2
12.6
77.7
76.4
ml/min/173m2
0.59
377
3303
35
365
0.96
0.06
1.5
1.7
1.6
1.5
%
0.77
30
314
54
526
1.03
0.04
1.4
1.4
—
—
—
0
0
374
3725
1.01
0.03
35.1
14.5
38.7
39.3
%
0.69
235
2503
25
241
1.04
0.02
2.3
1.9
—
—
—
0
0
25
241
1.04
0.02
1.1
1.2
53.2
127.9
iu/ml
1.53
14
95
26
268
0.97
0.02
2.3
2.0
—
—
—
0
0
391
3902
1.01
0.01
5.4
4.7
1.9
2.3
mu/l
0.73
360
3481
12
115
1.04
0.00
1.7
1.8
—
—
—
0
0
17
169
1.01
0.00
3.9
3.0
19.2
1743.7
u/ml
1.00
17
146
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
1.2
—
0
6
0
5
0.00
0.00
0.0
1.2
—
10.8
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_OTHER_MYCOBAC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_OTHER_MYCOBAC | 1.906 [1.65, 2.2] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.125 |
During the follow-up period (1.1.1998 — 31.12.2019), 658 out of 1676 females with AB1_OTHER_MYCOBAC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_OTHER_MYCOBAC | 2.693 [2.15, 3.37] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 619 out of 1250 males with AB1_OTHER_MYCOBAC died.
Mortality risk
Mortality risk for people of age
years, who have AB1_OTHER_MYCOBAC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.197% | 0.472% |
| 5 | 1.066% | 2.948% |
| 10 | 2.455% | 6.89% |
| 15 | 4.73% | 12.749% |
| 20 | 8.37% | 21.26% |
Relationships between endpoints
↥Index endpoint: AB1_OTHER_MYCOBAC – Infection due to other mycobacteria
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data