facial nerve disease: A disease involving the facial nerve.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1116 |
4. Check minimum number of eventsNone |
1116 |
5. Include endpointsNone |
1116 |
6. Filter based on genotype QC (FinnGen only) |
1083 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G50-G59
- Name in latin
- Morbositates nervi facialis
Similar endpoints
↥List of similar endpoints to
Other facial nerve disorders
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7545 | 4598 | 2892 |
| Only index persons | 6698 | 4159 | 2539 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.13 | 0.08 |
| Only index persons | 0.13 | 0.15 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 54.85 | 55.37 | 53.90 |
| Only index persons | 53.10 | 53.57 | 52.33 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1083 | 720 | 363 |
| Unadjusted period prevalence (%) | 0.23 | 0.26 | 0.17 |
| Median age at first event (years) | 53.69 | 52.83 | 55.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1116
- Matched controls
- 11160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G51.3
ICD-10 Finland
Clonic hemifacial spasm
+∞
307.7
433
*
G51.9
ICD-10 Finland
Disorder of facial nerve, unspecified
+∞
261.0
240
*
G51.0
ICD-10 Finland
Bell palsy
631.7
260.3
248
5
G51.4
ICD-10 Finland
Facial myokymia
497.5
247.5
238
6
N03AE01
ATC
clonazepam; systemic
10.2
178.5
222
264
3AX01, ,
NOMESCO Finland
83.6
159.9
85
11
ZX114
NOMESCO Finland
Intramuscular
18.8
130.6
106
62
G51.8
ICD-10 Finland
Other disorders of facial nerve
+∞
116.8
110
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.4
108.6
137
163
G24.5
ICD-10 Finland
Blepharospasm
361.8
100.8
100
*
G50.1
ICD-10 Finland
Atypical facial pain
21.5
83.4
63
31
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
13.2
81.1
79
64
G50.0
ICD-10 Finland
Trigeminal neuralgia
30.3
78.3
52
18
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
26.3
61.7
43
17
G51.1
ICD-10 Finland
Geniculate ganglionitis
+∞
58.9
56
*
3519X
ICD-9 Finland
Facial nerve disorders, Facial nerve disorder, unspecified
+∞
54.6
52
*
N03AX12
ATC
[U] gabapentin; oral
3.3
52.2
238
850
G51.2
ICD-10 Finland
Melkersson syndrome
+∞
49.3
47
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.0
47.7
152
428
G54.0
ICD-10 Finland
Brachial plexus disorders
14.4
47.0
43
31
ACC51
NOMESCO Finland
Release of median nerve
78.0
46.4
52
7
AAH60
NOMESCO Finland
Microvascular decompression of cranial nerve
+∞
43.0
41
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
56.8
41.8
49
9
N03AX16
ATC
[U] pregabalin
2.6
39.9
299
1379
G51
ICD-10 Finland
Facial nerve disorders
+∞
36.7
35
*
R51.81
ICD-10 Finland
Facial pain NOS
7.2
36.3
55
80
TAB00
NOMESCO Finland
Lumbar puncture
4.4
34.0
88
211
N06AX21
ATC
duloxetine; oral
3.0
33.4
171
643
G24.3
ICD-10 Finland
Spasmodic torticollis
9.4
33.2
40
44
H02AB06
ATC
prednisolone; systemic
2.1
32.9
573
3708
R51.80
ICD-10 Finland
Headache
2.6
32.5
225
988
N03AF01
ATC
carbamazepine; oral, rectal
4.3
31.4
86
215
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
31.1
129
428
N02AX02
ATC
tramadol; systemic, rectal
2.1
30.1
496
3111
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
27.5
525
3440
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
27.1
130
469
G44.2
ICD-10 Finland
Tension-type headache
2.5
26.6
192
855
M03BX01
ATC
baclofen; systemic
6.9
26.5
41
61
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
25.8
433
2697
XA402
NOMESCO Finland
ENMG
6.6
25.3
41
64
R20.2
ICD-10 Finland
Paraesthesia of skin
3.2
25.1
105
349
3518X
ICD-9 Finland
Facial nerve disorders, Other facial nerve disorders
+∞
25.1
24
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
133.0
24.7
26
*
N03AF02
ATC
oxcarbazepine; oral
4.8
24.3
56
122
N06AX16
ATC
venlafaxine; oral
2.4
23.7
192
898
H02.2
ICD-10 Finland
Lagophthalmos
37.2
23.1
29
8
G24.8
ICD-10 Finland
Other dystonia
46.0
22.4
27
6
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
22.4
153
661
N06AA09
ATC
amitriptyline; systemic
2.7
22.0
125
493
A02BC05
ATC
esomeprazole; systemic
1.9
21.5
470
3146
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.9
21.2
63
167
R42
ICD-10 Finland
Dizziness and giddiness
2.0
21.1
273
1532
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
8.2
21.0
28
35
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.6
20.9
133
555
M03AX01
ATC
botulinum toxin; parenteral
7.2
20.9
31
44
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.3
20.7
82
264
K07.60
ICD-10 Finland
Snapping jaw
3.3
20.4
78
245
M54.5
ICD-10 Finland
Low back pain
1.8
20.2
410
2668
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
19.7
187
930
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
19.7
270
1543
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
203.5
19.6
20
*
M79.7
ICD-10 Finland
Fibromyalgia
4.0
19.3
56
146
M79.6
ICD-10 Finland
Pain in limb
1.8
19.1
467
3201
M03BX02
ATC
tizanidine; oral
1.8
19.0
697
5371
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
+∞
18.8
18
*
AA1AD
NOMESCO Finland
CT of head and brain
1.9
18.6
299
1798
H02.4
ICD-10 Finland
Ptosis of eyelid
4.1
18.4
52
133
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
19.7
18.2
27
14
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.1
18.2
50
125
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
18.2
150
703
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
17.9
257
1486
N02BF01
ATC
gabapentin; oral
2.8
17.8
94
356
R52.9
ICD-10 Finland
Pain, unspecified
2.5
17.7
122
527
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.4
17.6
29
46
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
17.5
487
3443
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
17.5
83
297
M01AH05
ATC
etoricoxib; oral
1.7
17.3
685
5330
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
17.2
159
780
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
16.9
138
643
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
16.8
149
720
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
16.6
166
841
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
16.2
60
185
N03AX11
ATC
topiramate; oral
4.2
16.0
43
106
G56.2
ICD-10 Finland
Lesion of ulnar nerve
12.5
15.9
28
23
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.0
15.8
34
70
A02BC01
ATC
omeprazole; systemic
1.8
15.7
298
1874
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.6
15.7
53
154
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.3
15.5
26
42
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
15.5
205
1149
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
15.3
88
348
N02BE01
ATC
paracetamol; systemic, rectal
2.1
15.3
984
8672
J01DB01
ATC
cefalexin; oral
1.9
15.1
904
7746
UJF32
NOMESCO Finland
Coloscopy
1.8
15.1
283
1771
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
15.1
264
1619
A02BC02
ATC
pantoprazole; systemic
1.7
14.8
733
5933
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
14.6
514
3811
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
14.5
106
470
G24.4
ICD-10 Finland
Idiopathic orofacial dystonia
151.9
14.5
15
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
14.0
256
1587
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.1
13.9
38
95
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
13.9
109
499
G47.3
ICD-10 Finland
Sleep apnoea
1.8
13.8
244
1495
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.6
472
3466
M01AC06
ATC
meloxicam; systemic, rectal
1.7
13.5
393
2761
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
13.5
99
440
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.7
13.4
72
275
N06AX11
ATC
mirtazapine; oral
1.7
13.4
367
2540
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.0
13.3
38
98
J02AC01
ATC
fluconazole; systemic
1.6
13.2
446
3247
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
13.2
296
1941
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
13.1
86
363
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
4.1
12.9
35
87
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.6
12.9
30
66
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.2
12.8
34
83
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.6
12.7
73
289
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
12.7
87
375
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
12.6
103
479
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
12.4
387
2755
A02BC03
ATC
lansoprazole; oral
1.7
12.3
307
2064
R52.2
ICD-10 Finland
Other chronic pain
3.3
12.3
47
148
G44.0
ICD-10 Finland
Cluster headache syndrome
5.9
12.3
22
38
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
6.1
12.2
21
35
SFA10
NOMESCO Finland
One-surface restoration
1.6
12.1
583
4584
R25.3
ICD-10 Finland
Fasciculation
18.3
12.1
18
10
R06.0
ICD-10 Finland
Dyspnoea
1.7
12.0
278
1833
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
11.9
585
4616
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
11.9
89
399
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
11.8
99
465
M01AE02
ATC
naproxen; oral, rectal
1.6
11.8
607
4833
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
11.8
265
1730
R4120
NOMESCO Finland
Occupational therapy
2.5
11.8
74
306
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
11.6
509
3906
QAJ10
NOMESCO Finland
Browlift
23.2
11.6
16
7
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
11.6
320
2204
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
11.5
155
869
119
Kela drug reimbursment
Trigeminal neuralgia or glossofaryngeusneuralgia
+∞
11.5
11
*
R25.2
ICD-10 Finland
Cramp and spasm
3.8
11.5
35
95
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
11.4
282
1886
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
11.4
118
603
R01AD09
ATC
mometasone; nasal
1.6
11.3
487
3715
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
15.2
11.3
18
12
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.3
11.3
43
135
M54.2
ICD-10 Finland
Cervicalgia
2.2
11.3
93
434
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
11.2
181
1075
H57.1
ICD-10 Finland
Ocular pain
3.0
11.1
49
168
J01FA06
ATC
roxithromycin; oral
1.6
11.1
425
3155
G43.9
ICD-10 Finland
Migraine, unspecified
2.5
11.0
70
291
UDC00
NOMESCO Finland
Ear microscopy
2.3
11.0
83
373
M01AB05
ATC
diclofenac; systemic, rectal
1.6
11.0
694
5743
R03AC02
ATC
salbutamol; inhalant
1.5
11.0
584
4655
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.7
11.0
35
98
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
10.9
239
1546
XA800
NOMESCO Finland
Neuropsychological investigation
2.9
10.9
51
181
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
10.9
42
133
L03
ICPC
Low back symptom/complaint
1.6
10.9
279
1881
R52.1
ICD-10 Finland
Chronic intractable pain
10.7
10.8
20
19
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.3
10.8
84
383
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.4
10.7
39
119
TQA05
NOMESCO Finland
Puncture of skin of head or neck
60.6
10.6
12
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
10.6
104
521
N03AX09
ATC
lamotrigine; oral
2.7
10.6
56
213
SFA20
NOMESCO Finland
Two-surface restoration
1.5
10.5
616
4994
D07AC01
ATC
betamethasone; topical
1.6
10.4
372
2709
TCE00
NOMESCO Finland
Therapeutic injection into extraocular muscle
+∞
10.4
10
*
J01DA01
ATC
[U] cefalexin
1.5
10.3
658
5423
N02BF02
ATC
pregabalin; oral
2.5
10.2
66
277
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
10.2
548
4355
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.1
746
6328
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
10.0
216
1389
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
10.0
308
2165
R53
ICD-10 Finland
Malaise and fatigue
1.6
10.0
255
1714
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.2
10.0
39
125
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
9.9
290
2016
R60.0
ICD-10 Finland
Localized oedema
1.9
9.8
124
679
H16.0
ICD-10 Finland
Corneal ulcer
2.6
9.8
59
239
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
4.6
9.8
23
51
ZXA05
NOMESCO Finland
Left side
1.6
9.8
240
1596
SAA04
NOMESCO Finland
Special examination of mouth
2.5
9.8
62
258
C07AA05
ATC
propranolol; systemic
1.7
9.7
225
1473
XCK00
NOMESCO Finland
Perimetry
2.3
9.7
71
315
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
9.7
85
407
WVA30
NOMESCO Finland
Intramuscular and subcutaneous injection
13.5
9.7
16
12
G50.9
ICD-10 Finland
Disorder of trigeminal nerve, unspecified
55.5
9.7
11
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
9.6
149
871
R13
ICD-10 Finland
Dysphagia
2.2
9.6
77
356
L17
ICPC
Foot/toe symptom/complaint
1.6
9.6
283
1968
H01
ICPC
Ear pain/earache
1.9
9.6
116
627
K02.1
ICD-10 Finland
Caries of dentine
1.5
9.5
610
4996
F95.9
ICD-10 Finland
Tic disorder, unspecified
100.9
9.4
10
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
9.4
56
226
AAH30
NOMESCO Finland
Thermal destruction of cranial nerve
+∞
9.4
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.4
696
5864
R01AD58
ATC
fluticasone, combinations; nasal
1.6
9.4
252
1713
F29
ICPC
Eye symptom/complaint other
2.0
9.4
101
524
H02.3
ICD-10 Finland
Blepharochalasis
2.2
9.3
75
347
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.3
195
1244
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.3
401
3029
R12
ICD-10 Finland
Heartburn
2.1
9.2
88
437
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.6
9.2
53
211
ZXA00
NOMESCO Finland
Right side
1.6
9.1
258
1773
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.6
9.1
30
86
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.9
9.1
43
154
M48.0
ICD-10 Finland
Spinal stenosis
1.9
9.1
109
587
N05BA04
ATC
oxazepam; oral
1.6
9.1
276
1929
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.6
9.1
284
1999
N03
ICPC
Pain face
9.1
9.0
18
20
M54.3
ICD-10 Finland
Sciatica
2.4
9.0
63
274
M25.5
ICD-10 Finland
Pain in joint
1.5
9.0
327
2376
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
9.0
128
729
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
9.0
73
339
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
3.1
8.9
37
123
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
8.9
120
672
SPAT1263
SPAT
Sampling
1.5
8.9
420
3223
K59.09
ICD-10 Finland
Constipation, unspecified
2.2
8.9
73
341
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.9
364
2714
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.9
8.8
42
151
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.1
8.8
24
60
R03DC03
ATC
montelukast; oral
1.7
8.8
174
1091
Z3226
NOMESCO Finland
Physiotherapist
1.7
8.8
183
1165
M54.8
ICD-10 Finland
Other dorsalgia
2.6
8.7
50
198
R50.9
ICD-10 Finland
Fever, unspecified
1.7
8.7
153
929
A01
ICPC
Pain general/multiple sites
2.0
8.7
92
474
S29
ICPC
Skin symptom/complaint other
1.7
8.7
189
1216
SFA30
NOMESCO Finland
Three-surface restoration
1.5
8.7
434
3364
N06AA10
ATC
nortriptyline; systemic
3.5
8.7
29
84
E0000UV, ,
ATC
1.5
8.7
423
3264
Z50.1
ICD-10 Finland
Other physical therapy
2.4
8.6
56
236
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.0
8.6
38
131
J01AA02
ATC
doxycycline; systemic
1.5
8.6
827
7275
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
8.6
418
3222
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
27.7
8.5
11
*
R06AE07
ATC
cetirizine; oral
1.5
8.5
449
3517
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.0
8.4
99
529
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
8.4
134
791
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.9
8.4
99
531
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
8.3
162
1011
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
8.3
305
2216
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
8.3
113
635
M01AE51
ATC
ibuprofen, combinations; systemic
4.1
8.3
22
54
R49.08
ICD-10 Finland
Other specified dysphonia
3.4
8.2
29
87
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.2
414
3205
G24.9
ICD-10 Finland
Dystonia, unspecified
14.6
8.2
13
9
N02AA05
ATC
oxycodone; systemic
1.7
8.2
162
1015
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.9
8.2
38
135
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
8.2
111
623
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.1
748
6479
D01
ICPC
Abdominal pain/cramps general
1.8
8.1
122
707
WX704
NOMESCO Finland
Intubation
2.1
8.1
79
395
M77.1
ICD-10 Finland
Lateral epicondylitis
2.1
8.1
79
395
A02BA02
ATC
ranitidine; systemic
1.6
8.0
191
1258
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.0
246
1720
H02AB07
ATC
prednisone; oral
1.7
7.9
142
866
L02
ICPC
Back symptom/complaint
1.9
7.9
105
585
H53.2
ICD-10 Finland
Diplopia
2.7
7.9
41
155
M79.1
ICD-10 Finland
Myalgia
1.7
7.9
147
907
C07AB07
ATC
bisoprolol; oral
1.4
7.8
468
3733
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
7.8
61
279
D33.30
ICD-10 Finland
Acoustic neuroma
8.5
7.8
16
19
Z01.2
ICD-10 Finland
Dental examination
1.4
7.8
460
3660
M54.1
ICD-10 Finland
Radiculopathy
2.7
7.8
42
162
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.7
173
1119
WYA10
NOMESCO Finland
Emergency care or similar visit
2.0
7.7
81
416
N91
ICPC
Facial paralysis/bell's palsy
45.3
7.7
9
*
M01AH01
ATC
celecoxib; oral
1.6
7.7
177
1154
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.7
377
2897
M02AA07
ATC
piroxicam; topical
1.5
7.7
348
2634
KMAK, ,
NOMESCO Finland
1.4
7.6
527
4310
H02AB04
ATC
methylprednisolone; systemic
1.7
7.6
144
892
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
11.9
7.6
13
11
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.5
7.6
267
1919
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
7.6
243
1712
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.3
7.6
28
87
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.4
7.6
26
77
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
8.9
7.6
15
17
R06AX27
ATC
desloratadine; oral
1.5
7.5
288
2105
R01AD12
ATC
fluticasone furoate; nasal
1.5
7.5
323
2416
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.5
183
1209
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
7.5
106
602
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.4
273
1978
ACC53
NOMESCO Finland
Release of ulnar nerve
80.6
7.4
8
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
7.4
352
2684
J01CA04
ATC
amoxicillin; systemic
1.5
7.4
854
7648
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.4
188
1256
SPAT1260
SPAT
Consultation of another employee
1.6
7.4
168
1092
Z3231
NOMESCO Finland
Registered nurse
1.5
7.3
263
1895
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.3
377
2917
35008
ICD-8 Finland
Facial paralysis, Alia definita
+∞
7.3
7
*
2181
FHL
Root fracture, decompression or coagulation
+∞
7.3
7
*
G56.4
ICD-10 Finland
Causalgia
+∞
7.3
7
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
7.3
7
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
7.3
7
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
7.3
7
*
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
7.3
107
616
N02CC06
ATC
eletriptan; oral
2.6
7.2
42
168
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.6
7.2
42
168
M01AB08
ATC
etodolac; oral
2.0
7.2
79
412
TAC00
NOMESCO Finland
Peripheral nerve block
15.9
7.2
11
7
F45.8
ICD-10 Finland
Other somatoform disorders
2.0
7.2
75
384
G57.1
ICD-10 Finland
Meralgia paraesthetica
4.3
7.2
18
42
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
7.2
95
528
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
7.2
94
521
A07AA02
ATC
nystatin; oral
2.2
7.2
59
276
SPAT1301
SPAT
No procedures
1.5
7.2
296
2194
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
7.1
75
386
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.8
7.1
116
688
H92.0
ICD-10 Finland
Otalgia
2.2
7.1
62
297
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.1
184
1235
J02AC02
ATC
itraconazole; systemic
1.6
7.0
182
1219
L01
ICPC
Neck symptom/complaint
1.7
7.0
150
958
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.1
7.0
63
306
R01AD08
ATC
fluticasone; nasal
1.5
7.0
285
2108
J01FA10
ATC
azithromycin; systemic
1.4
6.9
581
4882
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
5.9
6.9
18
31
R07.3
ICD-10 Finland
Other chest pain
1.8
6.9
105
610
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
6.9
72
370
SBB10
NOMESCO Finland
Dental impressions
2.1
6.9
60
288
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
3.3
6.9
25
77
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
6.8
68
343
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.1
6.8
63
309
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.8
194
1328
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
6.8
78
414
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
6.8
161
1056
J01DA06
ATC
[U] cefuroxime
1.6
6.8
147
943
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.5
6.7
42
174
A04
ICPC
Weakness/tiredness general
1.7
6.7
138
872
P76
ICPC
Depressive disorder
2.0
6.7
68
345
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
3.5
6.7
22
63
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
6.7
46
199
R4110
NOMESCO Finland
Physiotherapy
1.5
6.7
269
1979
S18
ICPC
Laceration/cut
1.4
6.7
427
3419
SPAT1310
SPAT
Counselling related to known health issue
1.5
6.7
298
2238
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
3.8
6.7
20
54
Z2445
NOMESCO Finland
Psychologist
2.5
6.7
39
157
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
6.7
276
2044
XQ800
NOMESCO Finland
Prick test
2.0
6.6
73
383
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
6.6
86
477
R03BA05
ATC
fluticasone; inhalant
1.6
6.6
174
1171
P06
ICPC
Sleep disturbance
1.7
6.6
114
689
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.6
305
2308
M01AH02
ATC
rofecoxib; oral
1.7
6.5
117
713
P29
ICPC
Psychological sympt/compl other
2.0
6.5
69
356
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.5
96
554
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.5
408
3257
WZC00, ,
SPAT
1.8
6.4
94
540
N92
ICPC
Trigeminal neuralgia
70.2
6.4
7
*
D07AD01
ATC
clobetasol; topical
1.6
6.4
166
1111
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
6.4
196
1363
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.4
129
813
H50.52
ICD-10 Finland
Exophoria
4.1
6.4
17
42
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.1
6.3
25
81
G57.6
ICD-10 Finland
Lesion of plantar nerve
6.0
6.3
16
27
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
18.1
6.3
9
5
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.2
6.3
52
245
N02CX04, ,
ATC
3.0
6.3
26
87
35708
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Alterius nervi
+∞
6.3
6
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
6.3
6
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.5
6.3
39
162
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
2.9
6.2
28
98
M75.2
ICD-10 Finland
Bicipital tendinitis
3.1
6.2
25
82
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.7
6.2
19
52
S06.0
ICD-10 Finland
Concussion
1.7
6.2
104
623
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.6
6.2
20
57
J06
ICD-10 Finland
Acute upper respiratory infections of multiple and unspecified sites
2.4
6.2
39
163
H04.2
ICD-10 Finland
Epiphora
6.3
6.2
15
24
D06
ICPC
Abdominal pain localized other
1.9
6.2
80
443
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
5.4
6.2
17
32
N06AX26
ATC
vortioxetine; oral
1.9
6.2
71
378
N06AB04
ATC
citalopram; systemic
1.5
6.2
204
1442
R08
ICPC
Nose symptom/complaint other
2.5
6.2
37
151
F01
ICPC
Eye pain
2.8
6.2
30
110
SGB20
NOMESCO Finland
Root filling of tooth with onetwo root canals
2.0
6.1
67
350
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
6.1
125
789
D19
ICPC
Teeth/gum symptom/complaint
1.4
6.1
276
2074
P03
ICPC
Feeling depressed
1.8
6.1
90
519
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
6.1
55
268
K07.61
ICD-10 Finland
Cracking jaw joint
3.1
6.1
24
78
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
6.0
67
352
F61.0
ICD-10 Finland
Mixed personality disorders
3.5
6.0
20
58
M77.0
ICD-10 Finland
Medial epicondylitis
2.8
6.0
28
100
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.8
6.0
90
521
N80.9
ICD-10 Finland
Endometriosis, unspecified
3.3
6.0
22
68
L28
ICPC
Limited function/disability (L)
1.6
6.0
155
1037
M01AX05
ATC
glucosamine; oral
1.5
6.0
179
1237
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
401
2516
1.93
22.74
2.2
2.1
124.26
210.53
u/l
2.16
376
2364
34
51
6.84
21.77
1.0
1.0
1.35
1.10
u/l
0.40
13
27
35
56
6.42
21.09
1.1
1.1
33.20
41.03
mg/l
0.51
29
45
44
90
5.05
20.52
1.0
1.1
—
—
—
0
0
579
4210
1.78
19.50
6.1
6.5
1.22
1.21
mmol/l
0.12
487
3571
35
72
4.99
16.23
1.0
1.0
—
—
—
0
0
30
55
5.58
15.78
1.0
1.0
—
—
—
0
0
59
187
3.28
15.25
1.2
1.2
37.31
11.16
e6/l
0.45
45
141
59
187
3.28
15.25
1.2
1.3
147.30
2199.78
e6/l
0.75
47
146
518
3821
1.66
15.19
5.3
5.8
1.22
1.21
mmol/l
0.50
472
3468
646
5043
1.67
15.18
4.4
4.7
6.59
6.60
mmol/l
0.05
613
4690
794
6563
1.73
14.86
5.0
3.8
10.99
11.91
mm/h
1.09
756
6047
447
3206
1.66
14.40
3.7
3.4
27.71
50.37
ng/l
1.10
288
2147
718
5839
1.64
13.67
5.3
4.2
201.56
2960.18
e6/l
—
9
82
812
6867
1.67
12.72
8.1
7.3
75.41
77.57
u/l
1.01
776
6457
554
4278
1.59
12.67
6.8
5.9
28.67
27.98
%
0.85
524
4012
1005
9064
2.09
12.50
17.2
12.9
20.78
23.39
mg/l
1.62
811
7078
502
3833
1.56
11.76
12.5
14.3
1.18
1.24
inr
0.85
144
1130
543
4222
1.56
11.72
6.4
5.7
56.86
57.26
%
0.36
512
3956
826
7090
1.64
11.42
4.3
4.0
14.67
14.76
pmol/l
0.47
764
6448
463
3490
1.56
11.38
2.0
1.9
95.76
95.13
pmol/l
0.11
239
1769
558
4391
1.54
11.24
4.3
3.5
0.00
0.00
estimate
0.50
113
895
479
3645
1.55
11.24
5.1
4.7
36.55
35.68
g/l
3.17
445
3387
573
4538
1.54
11.19
5.8
6.2
10.04
11.06
umol/l
2.28
540
4314
1023
9385
2.08
10.59
18.1
14.8
3.94
3.95
mmol/l
0.82
999
9095
556
4417
1.52
10.43
5.6
4.8
0.00
0.00
estimate
0.50
108
837
633
5173
1.52
10.34
10.0
9.0
4.00
4.04
e9/l
0.17
566
4528
261
1756
1.63
10.20
2.5
2.5
4.60
6.38
e6/l
1.74
233
1591
559
4459
1.51
10.19
4.3
3.5
0.00
0.01
estimate
1.08
100
821
212
1354
1.70
10.11
3.2
3.4
0.83
0.81
mmol/l
1.24
195
1275
122
659
1.96
10.08
3.3
2.8
9.83
10.66
g/l
1.60
112
597
81
381
2.21
9.67
1.6
2.1
38.60
39.81
u/l
0.22
73
336
1017
9362
1.97
9.63
18.1
14.7
139.76
139.70
mmol/l
0.29
996
9092
227
1498
1.65
9.51
1.3
1.2
18.77
30.95
iu/ml
2.21
76
520
365
2692
1.53
9.49
2.6
2.5
56.19
61.41
u/l
1.04
337
2486
174
1075
1.73
9.32
2.4
2.3
91.80
122.55
ug/g
0.97
151
837
327
2381
1.53
8.92
3.4
2.9
0.30
0.48
e6/l
1.63
249
1794
348
2572
1.51
8.84
3.5
3.0
22.61
115.05
e6/l
1.98
272
1960
306
2231
1.51
8.19
3.5
3.7
92.35
92.03
%
0.08
300
2175
930
8452
1.60
7.83
5.3
4.7
1.80
2.03
mu/l
0.95
856
7766
129
768
1.77
7.83
1.9
2.1
362.95
378.00
nmol/l
0.40
118
710
106
597
1.86
7.72
1.7
1.6
—
—
—
0
0
195
1304
1.60
7.63
1.9
2.0
29.27
29.80
s
0.69
188
1262
257
1831
1.52
7.60
4.6
3.8
1.02
1.02
kg/l
0.53
40
256
30
98
3.12
7.47
1.9
1.3
—
—
—
0
0
168
1100
1.62
7.15
3.8
5.3
1.02
1.03
mmol/l
0.25
155
1011
427
3397
1.42
7.05
4.5
3.6
—
—
—
0
0
69
346
2.06
7.05
1.3
1.2
0.20
1.32
u/ml
—
6
25
310
2326
1.46
7.04
4.8
3.8
0.00
0.01
estimate
0.88
106
810
385
3008
1.43
7.03
3.4
3.5
2.35
2.36
mmol/l
0.80
349
2655
208
1455
1.53
6.62
3.2
2.5
1.37
1.35
e6/l
0.01
119
804
140
896
1.64
6.51
5.5
9.1
5.11
5.09
kpa
0.07
130
854
140
897
1.64
6.48
5.5
9.0
12.57
12.34
kpa
0.19
130
858
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
42
4.09
6.37
1.1
1.1
—
—
—
0
0
201
1418
1.51
6.12
1.3
1.2
7.21
14.98
u/ml
0.87
79
577
138
896
1.62
6.06
5.7
9.0
1.36
1.21
mmol/l
0.17
98
715
473
3919
1.36
5.79
3.2
2.7
102.43
119.45
ug/l
1.10
435
3606
16
31
5.22
5.71
1.2
1.2
—
—
—
0
0
450
3708
1.36
5.68
2.5
2.2
76.01
77.31
nmol/l
0.44
418
3325
904
8319
1.46
5.64
5.9
5.3
39.18
39.33
mmol/mol
0.20
845
7714
260
1959
1.43
5.61
1.5
1.5
18.84
20.94
nmol/l
1.71
228
1678
91
541
1.74
5.57
1.4
1.2
181.45
222.72
u/ml
0.25
82
491
684
6037
1.34
5.32
3.2
3.0
41.77
46.87
u/l
1.51
648
5642
299
2332
1.39
5.25
2.7
2.9
818.11
1159.03
ng/l
1.97
248
1963
75
429
1.80
5.25
1.4
1.3
23.06
27.91
iu/l
0.68
64
370
1028
9757
1.68
5.21
12.3
9.8
26.13
25.63
u/l
0.48
990
9412
490
4129
1.33
5.19
2.8
2.5
—
—
—
0
0
216
1600
1.43
5.08
3.9
3.5
65.28
360.87
ng/l
5.42
146
1198
331
2636
1.36
5.08
3.1
3.1
7.72
7.48
mmol/l
0.43
281
2241
258
1976
1.40
5.02
1.8
1.6
0.80
1.09
mg/l
2.60
191
1475
52
268
1.99
5.00
1.5
1.7
—
—
—
0
0
17
51
3.37
4.90
2.9
2.0
—
—
—
0
0
105
673
1.62
4.87
2.6
2.4
4.88
7.30
ug/l
1.10
92
592
277
2157
1.38
4.86
2.3
2.1
2.86
2.98
mg/l
0.43
228
1827
228
1719
1.41
4.85
1.5
1.4
2.13
2.45
g/l
2.22
144
1063
55
295
1.91
4.73
2.0
2.1
6136.54
4591.66
u/l
0.10
19
131
237
1808
1.39
4.69
1.7
1.6
172775284.32
24782748.13
pmol/l
0.52
191
1493
78
467
1.72
4.69
6.3
8.4
24.40
24.59
mmol/l
0.24
72
445
255
1974
1.38
4.62
1.4
1.2
1.36
1.57
u/ml
0.13
59
536
55
299
1.88
4.55
1.8
1.5
335.40
286.32
mu/l
0.27
55
271
11
19
5.84
4.44
1.2
1.2
—
—
—
0
0
211
1594
1.40
4.41
1.6
1.5
—
—
—
0
0
122
830
1.53
4.39
2.1
2.3
42.36
35.62
u/l
0.36
104
702
275
2178
1.35
4.28
2.4
2.5
1761.36
6534.29
umol/l
2.11
239
1921
185
1374
1.42
4.26
3.5
2.7
2.97
2.99
e6/l
0.01
98
724
861
7971
1.35
4.24
20.2
15.6
14.76
14.82
%
0.13
852
7816
17
57
3.01
4.13
1.4
2.1
—
—
—
0
0
10
17
5.92
4.13
1.0
1.2
—
—
—
0
0
99
652
1.57
4.12
2.9
3.5
79.32
81.66
ng/l
0.12
84
562
36
176
2.08
4.04
3.9
4.2
57.39
57.71
%
0.06
36
176
351
2907
1.30
3.95
3.0
3.1
30.95
32.59
u/l
0.48
337
2758
41
213
1.96
3.91
1.2
1.2
7.95
10.98
u/l
0.87
34
176
13
33
3.97
3.80
1.1
1.6
—
—
—
0
0
317
2608
1.30
3.71
3.8
3.7
4.24
8.89
mg/mmol
3.52
194
1604
11
25
4.43
3.62
1.0
1.1
—
—
—
0
0
140
1019
1.43
3.61
6.5
6.4
—
—
—
0
0
107
741
1.49
3.57
6.3
10.1
125.59
120.22
g/l
2.06
100
723
34
172
2.01
3.52
3.7
3.9
4.32
4.12
e9/l
0.16
34
172
11
26
4.26
3.51
1.0
1.1
—
—
—
0
0
1058
10235
1.65
3.45
25.0
19.1
252.15
253.53
e9/l
0.29
1040
9967
44
245
1.83
3.44
1.3
1.3
—
—
—
0
0
135
985
1.42
3.44
1.9
2.0
—
—
—
0
0
643
5804
1.25
3.41
3.3
3.0
—
—
—
0
0
13
37
3.54
3.41
1.1
1.1
—
—
—
0
0
1058
10239
1.64
3.39
24.9
19.1
6.64
6.63
e9/l
0.04
1041
9941
27
127
2.15
3.37
1.3
1.7
—
—
—
0
0
940
8904
1.35
3.35
4.7
4.3
5.88
5.87
mmol/l
0.04
866
8108
1058
10242
1.63
3.35
24.9
19.1
4.51
4.48
e12/l
0.80
1041
9946
196
1530
1.34
3.31
1.9
1.7
1104.18
1216.36
nmol/l
0.84
146
1137
19
77
2.49
3.30
1.5
1.2
5.06
1.02
u/ml
0.45
14
39
14
48
2.94
3.30
1.1
1.7
6.11
8.45
ug/l
0.39
14
43
1057
10234
1.62
3.29
25.0
19.2
40.18
40.06
%
0.24
979
9622
1058
10246
1.63
3.29
25.0
19.2
135.52
135.00
g/l
0.61
1047
10083
169
1299
1.35
3.16
2.1
2.3
12.94
13.35
umol/l
0.32
157
1209
122
890
1.42
3.12
1.9
1.9
—
—
—
0
0
5
5
10.04
2.98
1.0
1.4
—
—
—
0
0
171
1333
1.33
2.91
2.0
1.8
—
—
—
0
0
203
1625
1.30
2.87
3.2
3.0
2.44
2.45
mmol/l
0.91
180
1435
92
648
1.46
2.86
2.9
2.7
66.06
66.95
g/l
0.56
80
591
97
695
1.43
2.76
1.9
2.5
76.21
67.81
ml/min/173m2
1.30
42
279
23
111
2.09
2.74
1.2
1.4
0.47
0.63
nmol/l
2.06
23
105
16
67
2.41
2.64
1.1
1.1
—
—
—
0
0
16
67
2.41
2.64
1.1
1.1
—
—
—
0
0
9
25
3.62
2.57
1.0
1.1
—
—
—
0
0
8
20
4.02
2.57
1.4
1.6
75.25
73.70
%
—
8
20
8
20
4.02
2.57
1.4
1.6
1059.25
380.90
mu/l
—
8
20
16
68
2.37
2.56
1.1
1.1
—
—
—
0
0
16
68
2.37
2.56
1.1
1.1
—
—
—
0
0
16
68
2.37
2.56
1.1
1.1
—
—
—
0
0
123
931
1.36
2.55
1.7
1.8
—
—
—
0
0
30
164
1.85
2.55
5.2
11.0
106.96
105.54
mmol/l
1.50
24
147
122
924
1.36
2.53
1.8
1.7
—
—
—
0
0
10
31
3.25
2.52
1.1
1.0
—
—
—
0
0
152
1191
1.32
2.51
2.0
2.3
2.43
2.35
g/l
1.11
141
1104
80
564
1.45
2.50
2.1
3.4
4.19
4.51
pmol/l
2.12
73
495
9
26
3.48
2.48
2.4
1.9
—
—
—
0
0
143
1113
1.33
2.47
2.1
2.3
21.12
23.41
%
1.46
118
955
6
12
5.02
2.40
1.3
1.0
—
—
—
0
0
9
27
3.35
2.39
1.0
1.1
—
—
—
0
0
5
8
6.27
2.37
1.0
1.5
—
—
—
0
0
9
28
3.23
2.31
1.1
1.1
114.11
111.17
%
—
9
23
14
59
2.39
2.30
1.1
1.2
—
—
—
0
0
5
156
0.32
2.28
1.2
1.5
—
—
—
0
0
39
240
1.65
2.25
2.4
2.9
—
—
—
0
0
5
9
5.57
2.21
1.0
1.3
—
—
—
0
0
22
115
1.93
2.16
1.1
1.5
—
—
—
0
0
22
115
1.93
2.16
1.2
1.1
—
—
—
0
0
30
176
1.72
2.07
1.4
1.3
—
—
—
0
0
30
176
1.72
2.07
1.4
1.3
—
—
—
0
0
34
207
1.66
2.06
2.3
2.3
0.00
0.00
g/l
-0.00
28
187
44
286
1.56
2.06
2.3
2.2
6.98
7.28
g/l
0.53
38
255
44
286
1.56
2.06
2.2
2.2
3.57
3.56
g/l
0.02
38
255
44
286
1.56
2.06
2.2
2.2
—
—
—
0
0
42
271
1.57
2.03
2.1
1.5
541.00
181.82
titre
—
5
11
22
118
1.88
2.02
1.1
1.1
—
—
—
0
0
279
2409
1.21
2.02
1.6
1.6
1.38
1.36
mmol/l
0.16
241
2030
25
140
1.80
2.02
1.4
1.5
0.40
0.35
nmol/l
0.11
20
111
35
217
1.63
1.99
2.3
2.3
0.00
0.00
g/l
-0.00
29
196
48
321
1.52
1.99
1.3
1.4
—
—
—
0
0
945
9098
1.25
1.98
4.6
4.2
4.69
4.73
mmol/l
0.69
888
8454
47
313
1.52
1.98
4.5
7.1
1.60
1.55
%
0.14
41
293
41
265
1.57
1.97
2.1
2.2
2.99
2.95
g/l
0.06
35
234
37
234
1.60
1.95
1.4
1.5
288.82
297.48
ug/g
0.09
17
132
8
27
2.98
1.94
1.0
1.1
—
—
—
0
0
6
16
3.76
1.93
1.3
1.1
—
—
—
0
0
73
535
1.39
1.90
3.2
3.1
5.07
5.13
kpa
0.31
68
511
70
510
1.40
1.88
3.2
3.1
1.58
1.73
mmol/l
0.17
52
378
7
22
3.20
1.88
1.0
1.0
—
—
—
0
0
41
269
1.54
1.86
1.4
1.6
133.46
0.08
iu/ml
—
9
46
41
269
1.54
1.86
2.3
2.2
9.27
10.43
g/l
0.96
34
237
33
206
1.62
1.84
2.3
2.3
0.00
0.00
g/l
-0.00
28
187
96
739
1.33
1.84
5.0
7.6
1.25
1.35
mmol/l
0.50
91
716
5
12
4.18
1.82
1.8
1.2
—
—
—
0
0
206
1745
1.22
1.80
4.4
4.0
23.78
21.30
%
1.10
89
801
907
8717
1.22
1.80
15.1
12.0
82.60
82.03
ml/min/173m2
0.35
771
7180
113
893
1.30
1.80
4.5
4.3
224.42
244.11
u/l
1.06
106
848
36
232
1.57
1.78
1.5
1.2
—
—
—
0
0
9
195
0.46
1.73
1.8
1.5
—
—
—
0
0
13
61
2.14
1.72
1.5
2.5
7.71
0.59
u/field
—
7
27
5
13
3.86
1.71
1.0
1.1
78.20
94.00
%
—
5
13
252
2188
1.20
1.71
5.5
4.6
2.71
2.39
ug/l
0.21
231
1955
36
235
1.55
1.69
1.3
1.1
—
—
—
0
0
37
245
1.53
1.64
2.2
2.4
0.79
1.07
g/l
0.19
30
211
35
229
1.55
1.64
2.3
2.2
39.29
38.08
g/l
0.60
29
198
935
9034
1.22
1.63
4.5
4.2
1.46
1.49
mmol/l
1.42
879
8338
7
26
2.70
1.58
1.0
1.1
—
—
—
0
0
10
44
2.28
1.55
1.2
1.4
—
—
—
0
0
27
418
0.64
1.53
1.4
1.5
—
—
—
0
0
70
531
1.34
1.51
2.3
2.2
10.69
12.68
nmol/l
1.22
60
478
119
970
1.25
1.50
2.7
2.7
8.33
7.92
umol/l
0.05
104
849
954
9254
1.21
1.49
5.1
4.6
2.77
2.81
mmol/l
0.68
898
8543
57
420
1.38
1.48
3.1
2.6
0.20
0.23
e6/l
0.12
57
405
81
632
1.30
1.45
2.9
2.8
155.14
207.92
ng/l
0.91
71
582
18
103
1.76
1.41
1.9
2.5
12.14
26.98
mg/l
—
7
28
9
40
2.26
1.40
1.3
3.0
549.00
1246.85
u/ml
—
9
40
7
29
2.42
1.39
1.3
1.3
—
—
—
0
0
16
89
1.81
1.37
1.2
1.1
—
—
—
0
0
904
8743
1.18
1.37
4.1
3.7
1.32
1.28
mmol/l
0.99
845
8019
89
712
1.27
1.34
3.3
3.7
1.24
1.23
mmol/l
0.91
77
610
71
557
1.29
1.25
1.8
1.9
—
—
—
0
0
8
36
2.23
1.24
1.0
1.1
620.00
192.68
iu/ml
—
8
36
12
63
1.91
1.23
1.0
1.1
—
—
—
0
0
33
229
1.45
1.23
2.0
1.6
—
—
—
0
0
11
56
1.97
1.22
1.2
1.3
—
—
—
0
0
8
39
2.06
1.15
1.0
1.0
1732.88
1844.46
miu/ml
—
8
39
87
709
1.25
1.15
4.5
7.1
8.47
9.26
mmol/l
0.52
82
673
7
30
2.34
1.12
1.0
1.3
8.34
9.63
ug/l
—
7
30
38
277
1.38
1.11
3.1
1.7
—
—
—
0
0
44
329
1.35
1.10
2.4
1.9
—
—
—
0
0
28
193
1.46
1.10
2.3
1.7
—
—
—
0
0
5
21
2.39
1.09
1.2
1.6
—
—
—
0
0
37
270
1.38
1.08
1.1
1.2
—
—
—
0
0
9
46
1.96
1.03
1.0
1.0
—
—
—
0
0
237
2133
1.14
1.03
2.7
2.2
—
—
—
0
0
26
180
1.46
1.01
1.3
1.4
—
—
—
0
0
11
187
0.58
0.98
1.5
1.6
—
—
—
0
0
21
141
1.50
0.95
1.6
1.4
—
—
—
0
0
62
499
1.26
0.94
1.6
1.4
—
—
—
0
0
6
27
2.23
0.93
4.7
2.4
—
—
—
0
0
36
269
1.35
0.93
1.1
1.2
—
—
—
0
0
10
55
1.83
0.92
1.2
1.3
—
—
—
0
0
26
184
1.42
0.92
1.6
1.5
14955.30
17415.32
e6/l
0.10
20
140
106
908
1.18
0.89
3.0
3.2
—
—
—
0
0
8
42
1.91
0.88
1.3
1.1
—
—
—
0
0
15
95
1.59
0.87
1.6
1.6
61.25
62.22
%
—
8
69
19
128
1.49
0.86
2.3
1.7
—
—
—
0
0
19
128
1.49
0.86
2.3
1.7
—
—
—
0
0
14
88
1.60
0.84
2.9
3.7
—
—
—
0
0
55
444
1.25
0.83
1.7
1.8
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
6
32
1.88
0.82
1.0
1.1
130.00
118.75
%
—
6
32
26
189
1.38
0.81
2.6
1.7
—
—
—
0
0
58
478
1.23
0.75
1.3
1.3
—
—
—
0
0
22
158
1.40
0.75
1.4
1.1
0.25
3.29
u/ml
2.29
13
79
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
30
228
1.32
0.73
1.5
1.3
—
—
—
0
0
15
100
1.51
0.73
1.8
1.2
—
—
—
0
0
14
92
1.53
0.72
1.0
1.6
—
—
—
0
0
14
92
1.53
0.72
1.0
1.6
—
—
—
0
0
19
134
1.43
0.71
1.1
1.1
—
—
—
0
0
20
143
1.41
0.70
1.4
1.6
—
—
—
0
0
25
331
0.75
0.70
3.7
3.4
39.45
4144.17
u/ml
0.77
20
287
29
221
1.32
0.70
1.5
1.2
—
—
—
0
0
26
195
1.34
0.70
2.2
2.1
42.56
78.71
ug/min
0.48
12
116
19
135
1.41
0.69
1.2
1.1
—
—
—
0
0
118
1045
1.14
0.68
1.7
1.8
1.59
1.45
%
0.74
100
914
5
27
1.86
0.68
1.2
1.3
—
—
—
0
0
38
303
1.26
0.67
1.9
1.8
—
—
—
0
0
18
128
1.41
0.66
1.4
1.5
—
—
—
0
0
32
251
1.28
0.64
1.7
1.8
6.61
5.43
iu/l
—
7
84
22
163
1.36
0.64
1.1
1.3
—
1.82
—
0
16
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
24
183
1.32
0.60
1.7
1.4
—
—
—
0
0
58
492
1.19
0.59
1.1
1.0
—
—
—
0
0
77
670
1.16
0.59
1.2
1.2
65.61
144.23
iu/ml
3.39
28
271
15
205
0.73
0.54
1.3
1.6
—
—
—
0
0
6
38
1.58
0.54
1.2
1.1
—
—
—
0
0
17
227
0.75
0.53
1.5
1.4
—
—
—
0
0
17
227
0.75
0.53
1.5
1.4
—
—
—
0
0
17
227
0.75
0.53
1.5
1.4
—
—
—
0
0
86
761
1.14
0.53
3.3
3.1
2.01
1.94
mmol/l
0.10
72
626
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
17
226
0.75
0.52
1.5
1.4
—
—
—
0
0
6
40
1.50
0.51
3.3
2.8
35933.33
39250.13
ug/l
—
6
40
23
179
1.29
0.51
2.3
2.2
127.53
130.00
g/l
0.16
17
134
16
118
1.36
0.50
1.1
1.0
—
—
—
0
0
19
246
0.77
0.49
1.5
1.5
—
—
—
0
0
7
47
1.49
0.47
1.3
2.0
3.71
2.03
u/field
—
7
35
86
774
1.12
0.43
3.3
3.0
5.99
5.84
kpa
0.84
80
747
5
33
1.52
0.41
2.0
1.2
—
—
—
0
0
5
33
1.52
0.41
2.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
37
315
1.18
0.40
2.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
2.9
—
0.69
—
0
12
79
874
0.90
0.40
4.2
4.3
3.71
25.25
ug/l
1.51
64
712
26
214
1.22
0.39
1.5
1.3
—
—
—
0
0
32
378
0.84
0.39
1.6
1.4
—
—
—
0
0
14
106
1.32
0.39
2.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
0.91
—
0
13
11
80
1.38
0.38
1.0
1.2
—
—
—
0
0
9
68
1.33
0.37
2.3
1.6
—
—
—
0
0
14
107
1.31
0.37
2.0
1.3
—
—
—
0
0
14
107
1.31
0.37
2.0
1.3
—
—
—
0
0
5
37
1.35
0.37
5.8
1.9
—
—
—
0
0
5
37
1.35
0.37
5.8
1.9
—
—
—
0
0
17
134
1.27
0.37
1.4
1.0
0.21
2.30
u/ml
—
9
68
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
253
1.19
0.37
3.2
2.5
0.33
0.34
u/ml
0.10
20
141
57
507
1.13
0.36
1.6
1.6
—
—
—
0
0
12
90
1.34
0.36
2.0
1.7
—
—
—
0
0
5
77
0.65
0.35
1.2
1.6
0.97
1.02
g/l
—
5
77
180
1698
1.07
0.35
1.5
1.4
—
—
—
0
0
9
124
0.72
0.35
1.3
1.3
6.98
7.40
mmol/l
—
9
106
6
45
1.34
0.33
2.2
1.5
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
6
46
1.31
0.33
2.2
1.5
—
—
—
0
0
6
47
1.28
0.32
8.3
3.4
—
—
—
0
0
18
146
1.24
0.32
1.2
1.1
1.36
1.69
u/ml
0.67
11
39
43
380
1.14
0.31
1.5
1.8
2.45
4.54
mg/l
0.72
34
272
7
53
1.32
0.31
1.1
1.1
—
—
—
0
0
7
55
1.27
0.30
1.1
1.5
179.37
154.67
pmol/l
—
7
55
32
278
1.16
0.30
1.5
1.3
223.34
239.47
miu/ml
0.10
11
133
11
140
0.78
0.28
1.3
1.2
—
—
—
0
0
31
353
0.87
0.27
2.5
1.9
1.77
1.51
g/l
0.79
26
308
14
113
1.24
0.26
1.6
1.5
—
—
—
0
0
13
104
1.25
0.26
2.1
1.3
—
—
—
0
0
13
104
1.25
0.26
2.1
1.3
—
—
—
0
0
136
1287
1.06
0.26
3.0
2.9
0.75
0.74
ug/l
0.01
88
825
9
74
1.22
0.25
3.8
1.9
—
—
—
0
0
9
74
1.22
0.25
1.0
1.0
—
—
—
0
0
13
105
1.24
0.25
2.1
1.3
—
—
—
0
0
84
896
0.93
0.23
1.9
1.7
—
—
—
0
0
5
40
1.25
0.22
2.0
1.2
—
—
—
0
0
5
40
1.25
0.22
2.0
1.2
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
13
107
1.22
0.21
1.2
1.1
—
—
—
0
0
8
103
0.78
0.21
2.4
2.0
13.50
13.11
%
—
8
103
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
21
184
1.14
0.19
5.7
3.3
36.76
25.50
mg/l
0.50
12
110
6
52
1.15
0.19
1.0
1.3
—
—
—
0
0
7
59
1.19
0.18
1.7
1.6
5.57
5.52
u/l
—
7
54
7
60
1.17
0.18
1.9
1.4
70.57
77.57
umol/l
—
7
60
11
91
1.21
0.17
1.3
1.0
0.06
0.45
u/ml
—
6
28
16
138
1.16
0.17
3.3
1.8
—
—
—
0
0
7
63
1.11
0.17
8.1
1.9
—
—
—
0
0
8
70
1.14
0.16
4.0
1.7
—
—
—
0
0
8
70
1.14
0.16
4.0
1.7
—
—
—
0
0
8
70
1.14
0.16
4.0
1.7
—
—
—
0
0
27
245
1.10
0.15
5.1
3.6
33.52
77.27
mg/l
0.94
20
191
14
121
1.16
0.15
1.9
1.6
—
—
—
0
0
9
81
1.11
0.15
3.9
1.8
—
—
—
0
0
15
165
0.91
0.09
5.9
3.6
80.47
2282.08
u/ml
0.81
15
154
6
56
1.07
0.08
2.2
1.5
—
—
—
0
0
10
113
0.88
0.08
2.3
1.9
89.52
89.56
%
—
10
113
5
63
0.79
0.08
1.0
1.1
—
109.60
—
0
5
5
65
0.77
0.08
1.2
1.3
1.33
1.57
g/l
—
5
65
37
352
1.05
0.08
3.5
3.1
46.43
46.85
%
0.04
37
346
25
266
0.94
0.07
1.4
1.5
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
24
225
1.07
0.07
2.7
1.5
—
—
—
0
0
30
284
1.06
0.07
2.1
2.0
96.53
91.35
%
0.59
30
274
8
77
1.04
0.07
1.5
2.1
—
—
—
0
0
26
245
1.06
0.07
5.2
3.7
23.78
46.98
mg/l
1.03
19
192
14
128
1.09
0.06
1.1
1.1
1.61
2.25
u/ml
—
7
60
106
1083
0.98
0.06
4.5
4.2
31.49
32.10
%
0.25
78
736
17
158
1.08
0.06
1.1
1.2
25.56
40.33
u/l
0.45
17
131
25
239
1.05
0.04
5.2
3.6
—
1.82
—
0
22
10
92
1.09
0.03
1.0
1.2
49.20
52.13
u/l
—
10
86
12
112
1.07
0.03
1.7
1.6
—
—
—
0
0
10
93
1.08
0.02
2.3
2.2
—
—
—
0
0
26
268
0.97
0.02
2.3
2.3
141.88
183.79
%
2.59
26
257
17
177
0.96
0.01
3.5
2.4
17.11
16.43
%
—
10
90
19
186
1.02
0.00
1.3
1.2
—
—
—
0
0
14
142
0.99
0.00
1.3
1.1
1.20
4.51
u/ml
—
5
51
13
133
0.98
0.00
3.5
5.5
358.85
373.11
umol/l
0.21
13
111
11
105
1.05
0.00
1.1
2.1
3.75
5.16
umol/l
0.81
11
72
5
52
0.96
-0.00
1.0
1.1
7.80
14.82
u/l
—
5
45
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.6
2.0
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
20.73
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
2.9
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.1
60.40
73.47
u/l
—
5
47
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
38.78
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
6.90
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
7.84
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
18.80
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_FACOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FACOTH | 1.072 [0.96, 1.2] | 0.232 |
| Birth year | 0.993 [0.98, 1.0] | 0.123 |
During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 3574 females with G6_FACOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FACOTH | 1.074 [0.94, 1.22] | 0.275 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 437 out of 2198 males with G6_FACOTH died.
Mortality risk
Mortality risk for people of age
years, who have G6_FACOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.101% | 0.153% |
| 5 | 0.581% | 1.052% |
| 10 | 1.446% | 2.663% |
| 15 | 2.94% | 5.251% |
| 20 | 5.264% | 8.985% |
Relationships between endpoints
↥Index endpoint: G6_FACOTH – Other facial nerve disorders
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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