Complications of anaesthesia during pregnancy

O15_PREG_ANESTH_COMPL

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule only females	293218
2. Check conditions None	293218
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O29 Cause of death: ICD-10 — O29 2 out of 7 registries used, show all original rules.	83
4. Check minimum number of events None	83
5. Include endpoints None	83
6. Filter based on genotype QC (FinnGen only)	80

Control definitions (FinnGen only)

Control exclude: O15_PREG_OTHER_MAT_DISORD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF3
Parent code in ICD-10: O20-O29
Name in latin: Complicationes anaesthesiae in graviditate

NAME	O15_PREG_ANESTH_COMPL
CONTROL_EXCLUDE	O15_PREG_OTHER_MAT_DISORD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O29
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O29
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Complications of anaesthesia during pregnancy based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	550	550	-
Only index persons	550	550	-
Unadjusted period prevalence (%)
Whole population	0.02	0.02	-
Only index persons	0.02	0.02	-
Median age at first event (years)
Whole population	-	30.03	-
Only index persons	-	30.03	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	80	80	-
Unadjusted period prevalence (%)	0.03	0.03	-
Median age at first event (years)	29.85	29.85	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
83: Matched controls
830

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

O29.4

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during pregnancy

+∞

65.5

TAB22

NOMESCO Finland

Stoppin epidural fluid escape with coagulated blood

88.5

33.7

O24.4

ICD-10 Finland

Diabetes mellitus arising in pregnancy

138.2

27.6

O29.9

ICD-10 Finland

Complication of anaesthesia during pregnancy, unspecified

+∞

15.0

O24.9

ICD-10 Finland

Diabetes mellitus in pregnancy, unspecified

+∞

13.9

O29.0

ICD-10 Finland

Pulmonary complications of anaesthesia during pregnancy

+∞

10.6

Z34.8

ICD-10 Finland

Supervision of other normal pregnancy

4.4

10.2

219

O20.9

ICD-10 Finland

Haemorrhage in early pregnancy, unspecified

20.7

9.8

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

5.4

9.3

MA2AE

NOMESCO Finland

Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus

4.0

8.8

236

MA2HE

NOMESCO Finland

Detailed morfological ultrasound examination of fetus

3.8

8.1

238

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

4.0

8.0

102

ZXD05

NOMESCO Finland

Urgent procedure

3.7

7.9

203

Z35.8

ICD-10 Finland

Supervision of other high-risk pregnancies

4.3

7.7

MA2DE

NOMESCO Finland

Detailed ultrasound examination of fetus including color doppler method

4.0

7.6

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

3.8

7.6

124

SPAT1196

SPAT

Monitoring of normal pregnancy

4.0

7.5

O24.0

ICD-10 Finland

Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent

+∞

7.4

Z30.2

ICD-10 Finland

Sterilization

4.8

7.4

TPH04

NOMESCO Finland

Cathetrisation of vein

4.1

7.1

O20.0

ICD-10 Finland

Threatened abortion

24.9

6.8

O21.0

ICD-10 Finland

Mild hyperemesis gravidarum

75.4

6.5

SPAT1197

SPAT

Extensive health check-up of expecting family

3.2

6.5

222

W85

ICPC

Gestational diabetes

19.9

6.4

O99.0

ICD-10 Finland

Anaemia complicating pregnancy, childbirth and the puerperium

29.1

6.4

WX321

NOMESCO Finland

Acute spinal anesthesia for delivery

4.1

6.3

WX306

NOMESCO Finland

Lumbar epidural anesthesy

3.7

6.3

Z39.2

ICD-10 Finland

Routine postpartum follow-up

3.1

6.2

219

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

3.63

4.67

1.8

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

2.89

3.29

1.7

1.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

474

2.53

3.19

4.9

3.4

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

5.41

3.13

2.0

1.7

7.53

6.97

mmol/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

112

2.46

3.04

2.1

2.0

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

10.52

3.01

2.0

1.6

5.04

5.34

mmol/l

—

(3045414) Leukocytes [Presence] in Urine

4.26

2.87

2.1

1.6

—

(3009261) Glucose [Presence] in Urine by Test strip

317

2.11

2.79

3.3

2.7

0.00

estimate

-0.00

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

239

2.09

2.69

3.2

2.4

—

(3035350) Ketones [Presence] in Urine by Test strip

311

2.07

2.68

3.3

2.6

0.00

estimate

-0.00

(3021601) Nitrite [Presence] in Urine by Test strip

310

1.99

2.41

4.2

3.8

0.00

estimate

-0.00

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

248

1.98

2.37

2.2

1.9

—

(3012544) pH of Venous blood

3.73

2.34

2.9

2.7

—

(3000850) Epithelial cells [#/volume] in Urine

2.33

3.5

2.1

8.29

8.15

e6/l

0.01

(3013826) Glucose [Moles/volume] in Serum or Plasma

296

1.94

2.27

4.1

3.4

6.35

5.96

mmol/l

0.50

246

(3029937) Albumin [Presence] in Urine by Test strip

158

2.05

2.26

3.7

2.7

0.00

0.02

estimate

0.49

(3020961) Endomysium IgA Ab [Titer] in Serum

3.02

2.23

1.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

2.39

2.14

3.0

3.4

2.58

23.76

mg/mmol

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

5.24

2.10

2.4

2.3

0.68

0.64

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.47

2.03

2.1

1.8

2.41

2.45

g/l

0.06

(3026008) Bacteria identified in Urine by Culture

164

1.96

2.01

3.8

1.8

—

(3022621) pH of Urine by Test strip

2.93

2.00

2.9

2.2

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

4.76

1.97

1.2

1.0

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

4.76

1.97

2.4

2.7

24.10

23.35

mmol/l

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

4.76

1.97

2.4

2.2

2.50

0.92

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

133

2.01

1.96

1.9

2.5

5.51

13.87

ng/l

—

(3023511) Choriogonadotropin [Units/volume] in Urine

2.35

1.95

1.6

1.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

336

1.83

1.92

2.6

2.3

—

(3019150) Specific gravity of Urine by Refractometry

127

2.00

1.88

3.5

2.4

1.02

kg/l

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

3.23

1.84

2.3

2.7

5.46

5.28

kpa

—

(3024354) Oxygen [Partial pressure] in Venous blood

3.51

1.78

2.2

2.4

5.43

5.22

kpa

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

686

2.69

1.73

11.8

8.4

16.27

18.08

mg/l

0.22

490

(3002582) Erythrocytes [#/volume] in Urine

139

1.91

1.72

4.2

2.4

28.19

79.88

e6/l

0.56

(3000991) Gas panel - Venous blood

3.32

1.69

1.8

6.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

216

1.78

1.69

1.5

1.6

97.24

95.62

pmol/l

0.06

123

(3024561) Albumin [Mass/volume] in Serum or Plasma

191

1.80

1.65

4.2

3.6

36.17

37.22

g/l

0.44

183

(3023103) Potassium [Moles/volume] in Serum or Plasma

610

2.13

1.64

9.2

6.9

3.87

mmol/l

0.02

579

(3022217) INR in Platelet poor plasma by Coagulation assay

158

1.83

1.62

3.5

6.0

1.01

1.04

inr

—

(1002224) Polysomnography panel

2.84

1.62

1.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

194

1.76

1.56

2.6

2.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

3.48

1.54

1.0

1.1

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

684

2.32

1.51

11.3

7.7

61.82

64.74

umol/l

1.69

684

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

154

1.79

1.48

5.2

2.7

—

(3014051) Protein [Presence] in Urine by Test strip

3.25

1.46

2.8

2.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

198

1.71

1.44

1.6

1.2

0.76

0.71

u/ml

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

2.20

1.40

1.5

1.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

610

1.94

1.37

9.4

6.9

139.14

139.39

mmol/l

0.48

585

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.89

1.33

2.9

2.1

44865.60

5259.11

u/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.06

1.30

1.5

1.3

—

(3021589) Normoblasts [#/volume] in Blood

285

1.61

1.30

6.9

6.7

0.00

e9/l

-0.00

232

(3023368) Bacteria identified in Blood by Culture

102

1.84

1.28

3.4

2.9

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.51

1.27

5.3

6.8

104.17

107.32

mmol/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.51

1.27

2.5

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

269

1.60

1.24

1.9

1.8

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.37

1.13

1.3

1.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

175

1.61

1.10

1.5

1.2

1.84

2.18

g/l

0.98

104

(40760892) CBC W Ordered Manual Differential panel - Blood

313

1.54

1.10

5.3

5.5

—

(3030467) Casts [#/volume] in Urine by Automated count

124

1.69

1.09

4.8

2.3

0.04

0.40

e6/l

1.34

(3000330) Specific gravity of Urine by Test strip

2.35

1.05

2.8

2.1

—

(3034274) Bile acid [Moles/volume] in Serum --fasting

2.35

1.05

1.2

1.6

2.76

4.49

umol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.94

1.02

1.7

1.2

—

(36304419) Bacteria [Presence] in Urine

127

1.64

1.00

4.4

2.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.03

0.99

1.9

2.4

0.22

0.24

g/l

—

(3042936) Bacteria identified in Isolate by Culture

1.84

0.99

1.8

1.9

—

(3044889) 12 lead EKG panel

339

1.48

0.96

2.8

2.1

—

(3025941) Bacteria identified in Stool by Culture

1.90

0.89

1.8

1.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

131

1.58

0.88

3.4

2.9

—

(3018095) Leukocytes [#/volume] in Urine

184

1.51

0.88

4.6

3.1

28.74

53.02

e6/l

0.40

105

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.82

0.85

1.1

1.8

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.74

0.80

1.1

1.3

—

(40761535) Cells panel - Urine sediment

2.15

0.76

4.4

3.3

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

1.61

0.75

1.4

1.3

97.64

180.25

iu/ml

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.06

0.74

1.2

1.0

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.06

0.74

1.2

1.0

—

(40761536) Microorganisms panel - Urine sediment

1.62

0.72

4.0

2.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

588

1.49

0.72

8.0

6.6

100.39

98.63

ml/min/173m2

0.37

440

(3000492) Spirometry study

1.73

0.72

1.5

1.2

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.98

0.72

1.2

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.98

0.72

1.2

1.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

101

0.56

0.67

1.0

1.5

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

1.83

0.67

1.6

1.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.71

0.62

1.8

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.1

—

1.38

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.61

0.0

2.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.61

0.0

1.2

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.1

—

2.90

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.53

0.60

1.4

1.5

392.23

436.19

pmol/l

0.49

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

684

1.56

0.58

5.0

4.1

—

(3000494) Fungus identified in Specimen by Culture

1.48

0.54

1.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

164

1.38

0.54

1.6

1.5

—

(3009508) Creatinine [Moles/volume] in Urine

119

1.43

0.53

2.9

2.4

6.76

7.52

mmol/l

0.35

108

(36660697) Celiac disease serology panel - Serum

1.56

0.52

1.3

1.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.61

0.50

1.1

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

251

1.31

0.49

1.8

1.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

101

0.67

0.42

1.9

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

101

0.67

0.42

1.9

1.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.50

0.41

1.0

1.8

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.1

—

0.08

—

(3002385) Erythrocyte distribution width [Ratio]

652

1.35

0.39

12.5

10.6

13.68

13.87

0.20

646

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.39

0.0

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.44

0.39

1.2

1.9

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.41

0.39

1.2

3.3

172.00

228.39

u/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.46

0.36

2.2

2.4

—

(3003338) MCHC [Mass/volume]

655

1.32

0.35

17.4

10.3

334.33

332.84

g/l

0.82

650

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

148

1.28

0.33

1.9

1.7

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

100

0.67

0.33

1.9

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

100

0.67

0.33

1.9

1.4

—

(3022145) Colonoscopy Study observation

1.35

0.32

1.3

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.30

0.31

1.0

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

1.36

0.29

2.0

1.3

462.60

300.49

mu/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

504

1.20

0.29

2.9

2.6

25.41

27.74

u/l

0.35

486

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.69

0.27

1.2

1.3

—

(3002256) Pathology report gross observation

1.26

0.26

1.2

1.1

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.73

0.25

1.5

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.30

0.23

2.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.27

0.23

1.4

1.2

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

17.43

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.3

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.7

—

(3003694) ABO and Rh group [Type] in Blood

272

1.16

0.21

1.9

1.8

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

186

1.17

0.19

2.2

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

343

1.14

0.19

2.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

110

1.22

0.18

1.7

1.4

—

(3005033) Fetal Nuchal fold Thickness US

0.75

0.16

1.5

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.74

0.16

1.5

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

201

1.13

0.13

1.9

1.8

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.20

0.13

1.4

1.7

—

(1761868) Lipid panel - Serum or Plasma

262

1.10

0.11

1.4

1.8

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

1.04

0.09

1.2

10.56

7.92

u/l

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.04

0.09

2.0

1.7

—

(40758558) Short blood count panel - Blood

144

0.88

0.09

11.1

7.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.08

0.09

1.3

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.78

0.08

1.6

2.7

28.60

33.81

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

153

0.90

0.08

2.1

1.7

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.03

0.07

1.5

2.0

2.38

2.39

mmol/l

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

1.08

0.07

1.4

13.70

19.31

iu/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.85

0.07

1.8

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

162

0.91

0.06

1.8

1.5

—

(3037522) Nuclear Ab [Titer] in Serum

100

1.12

0.05

1.5

1.4

616.00

532.31

titre

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

260

1.06

0.04

1.7

1.5

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.10

0.03

1.4

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

148

0.93

0.02

1.9

1.6

—

(3013512) EKG study

117

0.93

0.02

2.4

2.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

133

1.06

0.02

1.5

1.2

13.84

12.87

iu/ml

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

284

1.03

0.00

2.4

2.1

71.82

71.42

nmol/l

0.03

271

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

258

1.01

0.00

2.3

2.1

—

(21494755) Public health laboratory ask at order entry panel

117

1.03

0.00

1.3

1.2

—

(40768804) Tissue Pathology biopsy report

267

1.02

0.00

1.8

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

283

0.98

0.00

2.5

2.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

105

0.95

0.00

1.6

1.4

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

2.64

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

6.59

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.66

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.5

—

14.44

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3006270) Folate [Moles/volume] in Blood

0.00

-0.00

0.0

1.2

—

488.60

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.6

—

40.32

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

125.18

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.8

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(3008898) HLA-B27 [Presence]

0.92

-0.00

1.0

1.1

—

(1616796) Gas panel - Central venous blood

0.00

-0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.2

—

1.27

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

2.3

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

40.10

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

8.71

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.2

—

6.83

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

4.2

—

345.40

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.3

—

(3011288) Drugs identified in Urine by Screen method

1.00

-0.00

1.4

1.7

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.4

—

46.20

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

104.60

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(40768797) Stomach Pathology biopsy report

0.97

-0.00

1.0

1.1

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3029396) Erythrocyte agglutination [Presence] in Blood

0.00

-0.00

0.0

2.7

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

4.00

—

Mortality – FinRegistry

↥

Association

Association between endpoint O15_PREG_ANESTH_COMPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PREG_ANESTH_COMPL.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: O15_PREG_ANESTH_COMPL – Complications of anaesthesia during pregnancy

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Complications of anaesthesia during pregnancy

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints