Other birth injuries

P16_OTH_BIRTHINJI

No definition available.

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P15 Cause of death: ICD-10 — P15 2 out of 7 registries used, show all original rules.	23
4. Check minimum number of events None	23
5. Include endpoints None	23
6. Filter based on genotype QC (FinnGen only)	23

Control definitions (FinnGen only)

Control exclude: P16_BIRTH_TRAUMA

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P1[0-5]
Name in latin: Aliae laesiones intranatales

NAME	P16_OTH_BIRTHINJI
CONTROL_EXCLUDE	P16_BIRTH_TRAUMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P15
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P15
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Other birth injuries based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	680	281	398
Only index persons	440	187	253
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	0.24	0.13	0.12
Only index persons	0.16	0.15	0.17

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	23	13	10
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	4.21	0.32	9.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

4.12

1.89

1.2

1.4

—

(42870588) Differential panel, method unspecified - Blood

2.97

1.68

3.7

5.7

—

(3012544) pH of Venous blood

3.14

1.60

1.4

8.8

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.75

1.15

3.0

10.3

25.50

25.66

mmol/l

—

(3021960) Folate [Moles/volume] in Serum or Plasma

2.08

0.73

1.4

1.5

20.72

17.23

nmol/l

—

(3026008) Bacteria identified in Urine by Culture

1.91

0.72

4.0

2.7

—

(36304419) Bacteria [Presence] in Urine

1.82

0.69

3.8

3.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.75

0.55

3.6

5.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.61

0.52

1.4

2.2

—

(3030467) Casts [#/volume] in Urine by Automated count

1.73

0.51

3.9

3.5

0.00

0.43

e6/l

—

(3015736) pH of Urine

1.66

0.48

2.3

4.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

0.56

0.45

3.6

4.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.43

0.0

1.3

—

(3008898) HLA-B27 [Presence]

0.00

0.43

0.0

1.1

—

(40761535) Cells panel - Urine sediment

0.00

0.42

0.0

3.3

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1.54

0.42

3.8

4.8

0.54

1.91

ug/l

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.41

0.0

2.2

—

(1761868) Lipid panel - Serum or Plasma

1.53

0.39

2.5

2.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.49

0.36

1.4

2.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.48

0.34

3.9

3.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.35

0.32

2.7

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

121

1.40

0.29

5.6

4.6

—

(3048689) Calprotectin [Mass/mass] in Stool

1.49

0.26

3.8

2.1

35.40

45.25

ug/g

—

(3023368) Bacteria identified in Blood by Culture

1.36

0.25

3.4

4.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.37

0.23

2.2

2.6

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.22

0.0

9.0

—

98.45

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.22

0.0

1.3

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

0.22

0.0

8.6

—

2.54

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

0.00

0.22

0.0

1.5

—

87.00

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.22

0.0

1.6

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

0.22

0.0

3.6

—

36.60

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

16.1

—

1.17

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

105

1.30

0.15

6.8

5.0

29.25

38.09

u/l

0.45

(3044889) 12 lead EKG panel

114

0.78

0.13

5.1

2.6

—

(3018418) pH of Serum or Plasma

1.24

0.11

4.6

3.8

—

7.42

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

1.24

0.10

11.4

10.5

12.54

10.22

umol/l

—

(40758558) Short blood count panel - Blood

1.08

0.10

8.0

6.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.09

0.09

2.0

3.9

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

128

0.87

0.04

14.2

8.6

94.00

91.93

u/l

0.05

121

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

983.50

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

281.43

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.8

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(44790048)

0.00

0.0

1.2

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

1.50

—

(44790049)

0.00

0.0

1.2

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

2.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

18.64

—

(40768804) Tissue Pathology biopsy report

0.91

0.00

2.8

2.1

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

3.0

—

2.50

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.6

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.6

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.0

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

9.60

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.00

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.54

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

7.94

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3020891) Body temperature

0.00

0.0

2.9

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

2.1

—

(4306422)

0.00

0.0

1.8

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

165

1.12

0.00

4.5

3.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.05

0.00

2.6

4.5

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.8

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(44790047)

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.4

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.0

3.0

—

4.04

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.00

0.0

2.3

—

4.34

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.5

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

10.7

—

136.44

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.2

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.2

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

42.08

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.6

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.0

4.7

—

27.33

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.4

—

(44806118)

0.00

0.0

1.2

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

3.98

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.98

0.00

1.7

2.0

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_OTH_BIRTHINJI and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_BIRTHINJI.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_OTH_BIRTHINJI – Other birth injuries

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other birth injuries

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints