Other noninflammatory disorders of cervix uteri

N14_OTHNONINFCERVIX

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N88
  • Hospital discharge: ICD-9 622[2-9]
  • Hospital discharge: ICD-8 62191
  • Hospital discharge: excluded ICD-9 6227
  • Cause of death: ICD-10 N88
  • Cause of death: ICD-9 622[2-9]
  • Cause of death: ICD-8 62191
  • Cause of death: excluded ICD-9 6227

2 out of 7 registries used, show all original rules.

1928

4. Check minimum number of events

None

1928

5. Include endpoints

None

1928

6. Filter based on genotype QC (FinnGen only)

1928

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N80-N98
Name in latin
Aliae morbositates non inflammatoriae cervicis uteri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14923 14923 -
Only index persons 13264 13264 -
Unadjusted period prevalence (%)
Whole population 0.43 0.43 -
Only index persons 0.49 0.49 -
Median age at first event (years)
Whole population - 41.10 -
Only index persons - 40.27 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1928 1928 -
Unadjusted period prevalence (%) 0.66 0.66 -
Median age at first event (years) 39.26 39.26 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1737
Matched controls
17369
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
+∞
323.0
711
*
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
+∞
288.8
269
*
N88.4
ICD-10 Finland
Hypertrophic elongation of cervix uteri
+∞
271.1
253
*
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
140.0
219.4
231
19
N81.1
ICD-10 Finland
Cystocele
43.9
195.3
243
64
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
5.3
183.0
693
1918
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
166.3
157
*
N95.0
ICD-10 Finland
Postmenopausal bleeding
33.9
157.0
207
69
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
28.7
151.0
208
82
N81.6
ICD-10 Finland
Rectocele
36.8
145.5
188
57
N88.8
ICD-10 Finland
Other specified noninflammatory disorders of cervix uteri
+∞
142.7
135
*
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
30.3
136.5
185
68
8113
FHL
Fractional scraping
15.6
132.1
224
163
N84.0
ICD-10 Finland
Polyp of corpus uteri
77.6
126.7
143
20
LCA06
NOMESCO Finland
Biopsy of endometrium
8.3
120.6
287
405
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
612.8
117.5
115
*
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
255.2
117.4
119
5
6228X
ICD-9 Finland
Noninflammatory disorders of cervix, Other specified noninflammatory disorders of cervix
+∞
114.9
109
*
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
110.6
105
*
N88.9
ICD-10 Finland
Noninflammatory disorder of cervix uteri, unspecified
555.8
106.9
105
*
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
165.9
104.5
109
7
ULC02
NOMESCO Finland
Hysteroscopy
21.9
98.9
147
73
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
95.7
91
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
7.5
93.2
234
352
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
4.9
86.6
312
737
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
18.1
84.0
133
79
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
+∞
83.0
79
*
LDA00
NOMESCO Finland
Dilatation of cervix uteri
147.9
67.4
71
5
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
18.8
66.2
103
58
62699
ICD-8 Finland
Disorders of menstruation, Other
+∞
66.0
63
*
ULA02
NOMESCO Finland
Kolposcopy
4.7
64.3
235
554
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.7
59.5
218
513
N97.9
ICD-10 Finland
Female infertility, unspecified
83.1
57.3
64
8
LCD10
NOMESCO Finland
Vaginal hysterectomy
11.8
56.2
106
95
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
20.5
55.8
84
43
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
30.0
53.5
72
25
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
52.3
50
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
10.9
52.0
102
99
8326
FHL
Batch conization
47.7
49.5
60
13
N81.5
ICD-10 Finland
Vaginal enterocele
131.2
48.0
51
*
LEF10
NOMESCO Finland
Colpoperineoplasty
105.0
47.0
51
5
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
33.2
46.6
61
19
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.1
44.8
1136
8280
N84.1
ICD-10 Finland
Polyp of cervix uteri
38.5
44.3
56
15
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.9
43.6
196
554
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
4.9
42.8
148
325
N81.3
ICD-10 Finland
Complete uterovaginal prolapse
209.7
40.0
41
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
+∞
39.7
38
*
6226A
ICD-9 Finland
Noninflammatory disorders of cervix, Hypertrophic elongation of cervix
+∞
38.7
37
*
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
14.8
37.4
63
44
62000
ICD-8 Finland
Infective diseases of cervix uteri, Cervicitis chronica
+∞
36.6
35
*
6224A
ICD-9 Finland
Noninflammatory disorders of cervix, Stricture and stenosis of cervix
+∞
36.6
35
*
N80.0
ICD-10 Finland
Endometriosis of uterus
+∞
35.5
34
*
N81.4
ICD-10 Finland
Uterovaginal prolapse, unspecified
53.7
35.5
42
8
N99.3
ICD-10 Finland
Prolapse of vaginal vault after hysterectomy
31.4
34.9
46
15
N87.1
ICD-10 Finland
Moderate cervical dysplasia
343.5
34.0
34
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
333.1
33.0
33
*
LCA10
NOMESCO Finland
Curettage of body of uterus
16.5
33.0
53
33
N88.3
ICD-10 Finland
Incompetence of cervix uteri
+∞
32.4
31
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
3.1
31.6
191
674
LDA10
NOMESCO Finland
Curettage of cervix uteri
4.7
29.9
105
234
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
11.8
29.7
55
48
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
13.0
29.4
52
41
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
29.2
28
*
N80.1
ICD-10 Finland
Endometriosis of ovary
+∞
29.2
28
*
N85.9
ICD-10 Finland
Noninflammatory disorder of uterus, unspecified
296.6
28.8
29
*
6271A
ICD-9 Finland
Menopausal and postmenopausal disorders, Postmenopausal bleeding
+∞
28.2
27
*
LEF53
NOMESCO Finland
Vaginal colpopexy after previous hysterectomy
78.9
27.8
31
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
5.2
27.2
87
175
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
27.0
564
3581
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
25.8
339
1802
N39.3
ICD-10 Finland
Stress incontinence
2.8
25.7
173
651
XLA10
NOMESCO Finland
NA
3.6
25.3
120
353
62650
ICD-8 Finland
Disorders of menstruation, Irregular
+∞
25.1
24
*
6170A
ICD-9 Finland
Endometriosis of uterus
+∞
25.1
24
*
62198
ICD-8 Finland
Other diseases of cervix, Alii definiti
+∞
24.0
23
*
6180A
ICD-9 Finland
Genital prolapse, Prolapse of vaginal walls without mention of uterine prolapse[CYSTOCELE]
+∞
24.0
23
*
N97.8
ICD-10 Finland
Female infertility of other origin
+∞
24.0
23
*
LDW96
NOMESCO Finland
Other operation on cervix uteri
68.4
23.9
27
*
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
88.0
23.7
26
*
8433
FHL
Anterior and / or posterior colporal and cervical amputation (eg Manchester)
243.1
23.7
24
*
1390
FHL
Colposcopy
42.0
23.6
29
7
62620
ICD-8 Finland
Disorders of menstruation, Excessive
+∞
23.0
22
*
62698
ICD-8 Finland
Disorders of menstruation, Alia definita
+∞
23.0
22
*
6229X
ICD-9 Finland
Noninflammatory disorders of cervix, Unspecified noninflammatory disorder of cervix
+∞
23.0
22
*
H01CA02
ATC
nafarelin; nasal
10.5
22.6
44
43
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
35.5
22.1
28
8
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
15.3
22.0
36
24
G03GA01
ATC
chorionic gonadotrophin; parenteral
7.1
21.5
53
77
62801
ICD-8 Finland
Sterility, female, Sterilitas secundaria
+∞
20.9
20
*
N80.9
ICD-10 Finland
Endometriosis, unspecified
+∞
20.9
20
*
62533
ICD-8 Finland
Other diseases of uterus, Adenomyosis uteri
+∞
20.9
20
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
+∞
20.9
20
*
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
14.4
20.4
34
24
8112
FHL
Scraping the cervix
48.6
20.2
24
5
N93.8
ICD-10 Finland
Other specified abnormal uterine and vaginal bleeding
27.4
20.0
27
10
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
+∞
19.8
19
*
62530
ICD-8 Finland
Other diseases of uterus, Endometriosis ovarii
+∞
19.8
19
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
19.7
168
723
P01AB01
ATC
metronidazole; oral, rectal
1.6
18.9
701
5139
6171A
ICD-9 Finland
Endometriosis of ovary
+∞
18.8
18
*
LCA16
NOMESCO Finland
Destruction of endometrium
+∞
18.8
18
*
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
+∞
18.8
18
*
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
+∞
18.8
18
*
LEB00
NOMESCO Finland
Biopsy of vagina
7.6
18.4
43
58
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.8
18.1
330
1962
6173B
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS RETROUTERINA]
+∞
17.7
17
*
A02BC02
ATC
pantoprazole; systemic
1.6
17.1
1084
8967
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
17.0
499
3413
A02BC05
ATC
esomeprazole; systemic
1.6
16.8
654
4813
TLC02
NOMESCO Finland
Simple extraction of IUD
3.6
16.8
77
222
LDC10
NOMESCO Finland
Partial excision of cervix uteri
+∞
16.7
16
*
TLW10
NOMESCO Finland
Transfer of fresh embryo
+∞
16.7
16
*
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
+∞
16.7
16
*
N83.1
ICD-10 Finland
Corpus luteum cyst
+∞
16.7
16
*
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
16.7
16
*
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
3.3
16.6
84
261
B02AA02
ATC
tranexamic acid; systemic
2.0
16.6
232
1249
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
7.4
16.2
38
52
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
24.7
16.0
22
9
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
21.2
16.0
23
11
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
2.3
15.9
154
705
M03BX02
ATC
tizanidine; oral
1.5
15.9
1010
8284
UKC02
NOMESCO Finland
Cystoscopy
2.2
15.8
163
768
6270A
ICD-9 Finland
Menopausal and postmenopausal disorders, Premenopausal menorrhagia
+∞
15.6
15
*
62301
ICD-8 Finland
Uterovaginal prolapse, Cystocele alia
+∞
15.6
15
*
6210A
ICD-9 Finland
Disorders of uterus, not elsewhere classified, Polyp of corpus uteri
+∞
15.6
15
*
N97.4
ICD-10 Finland
Female infertility associated with male factors
+∞
15.6
15
*
62532
ICD-8 Finland
Other diseases of uterus, Endometriosis retro-cervicalis sive retrouterina
+∞
15.6
15
*
8322
FHL
Kerviks dilation
+∞
15.6
15
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
15.6
628
4635
N97.0
ICD-10 Finland
Female infertility associated with anovulation
161.3
15.5
16
*
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
4.2
15.5
58
140
G03GA02
ATC
human menopausal gonadotrophin; parenteral
6.9
15.5
38
56
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
5.8
15.4
43
75
N83.0
ICD-10 Finland
Follicular cyst of ovary
28.9
15.2
20
7
G03GA06
ATC
follitropin beta; parenteral
7.6
15.2
35
47
M01AE02
ATC
naproxen; oral, rectal
1.5
14.9
902
7273
N88.1
ICD-10 Finland
Old laceration of cervix uteri
+∞
14.6
14
*
6227A
ICD-9 Finland
Noninflammatory disorders of cervix, Mucous polyp of cervix
+∞
14.6
14
*
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
+∞
14.6
14
*
TLW00
NOMESCO Finland
Insemination
+∞
14.6
14
*
62630
ICD-8 Finland
Disorders of menstruation, Painful
+∞
14.6
14
*
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
+∞
14.6
14
*
LEF40
NOMESCO Finland
Vaginal repair of enterocele
151.2
14.5
15
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.8
14.3
92
337
8702
FHL
Placement of Cerglagen during pregnancy
22.4
14.2
20
9
78629
ICD-8 Finland
Symptoms referable to genito-urinary system, Incontinentia urinae
7.5
14.2
33
45
M54.5
ICD-10 Finland
Low back pain
1.6
14.1
492
3489
N02BE01
ATC
paracetamol; systemic, rectal
1.6
14.0
1454
13148
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
13.9
613
4588
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
3.6
13.9
62
176
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
20.2
13.8
20
10
6289B
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD SEC]
+∞
13.6
13
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
+∞
13.6
13
*
6253A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Dysmenorrhoea
+∞
13.6
13
*
6180C
ICD-9 Finland
Genital prolapse, Prolapse of vaginal walls without mention of uterine prolapse[RECTOCELE]
+∞
13.6
13
*
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
+∞
13.6
13
*
R32
ICD-10 Finland
Unspecified urinary incontinence
3.7
13.5
58
159
N81.8
ICD-10 Finland
Other female genital prolapse
141.0
13.5
14
*
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
16.3
13.5
21
13
SPAT1263
SPAT
Sampling
1.5
13.3
660
5057
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
13.1
389
2641
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
12.9
242
1440
C539, 6666, 0
ICD-O-3
NA
22.7
12.9
18
8
J02AC01
ATC
fluconazole; systemic
1.5
12.7
717
5630
X87
ICPC
Uterovaginal prolapse
17.4
12.5
19
11
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
+∞
12.5
12
*
62110
ICD-8 Finland
Other diseases of cervix, Erythroplasia of cervix
+∞
12.5
12
*
61521
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) corporis lutei ovarii
+∞
12.5
12
*
Z31.2
ICD-10 Finland
In vitrofertilization
+∞
12.5
12
*
N85.7
ICD-10 Finland
Haematometra
+∞
12.5
12
*
Y0609
ICD-8 Finland
Examination of the urinary and genital organs, Genital organs
4.2
12.4
46
111
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
1.8
12.3
211
1215
G03DA04
ATC
progesterone; systemic, rectal, vaginal
3.1
12.3
66
217
6256A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Stress incontinence, female
5.2
12.1
37
73
A02BC03
ATC
lansoprazole; oral
1.5
11.9
474
3442
J01DB01
ATC
cefalexin; oral
1.5
11.8
1293
11498
G04BD12
ATC
mirabegron; oral
2.0
11.7
154
806
UJF32
NOMESCO Finland
Coloscopy
1.6
11.7
373
2573
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
65.4
11.6
13
*
LEF51
NOMESCO Finland
Laparoscopic colpopexy after previous hysterectomy
65.4
11.6
13
*
JAH01
NOMESCO Finland
Laparoscopy
2.9
11.5
68
238
N89.0
ICD-10 Finland
Mild vaginal dysplasia
+∞
11.5
11
*
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
+∞
11.5
11
*
N88.0
ICD-10 Finland
Leukoplakia of cervix uteri
+∞
11.5
11
*
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
+∞
11.5
11
*
6182A
ICD-9 Finland
Genital prolapse, Uterovaginal prolapse, incomplete
+∞
11.5
11
*
6225A
ICD-9 Finland
Noninflammatory disorders of cervix, Incompetence of cervix
+∞
11.5
11
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
11.4
251
1563
G01AA10
ATC
clindamycin; vaginal
1.6
11.4
298
1948
J01CA08
ATC
pivmecillinam; oral
1.4
11.4
844
6937
J01EA01
ATC
trimethoprim; systemic
1.5
11.3
465
3395
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
8.4
11.3
24
29
8432
FHL
Anterior and / or posterior colaphia
35.2
11.3
14
*
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
20.2
11.1
16
8
G03GA05
ATC
follitropin alfa; parenteral
8.1
11.1
24
30
J01AA02
ATC
doxycycline; systemic
1.5
11.0
1290
11517
N76.0
ICD-10 Finland
Acute vaginitis
2.7
10.9
74
284
N30.0
ICD-10 Finland
Acute cystitis
1.7
10.9
249
1573
Z01.2
ICD-10 Finland
Dental examination
1.4
10.8
624
4878
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
10.6
10.8
20
19
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
6.2
10.7
28
46
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
28.2
10.7
14
5
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
28.2
10.7
14
5
1413
FHL
Laparoscopy and other therapeutic procedure
3.6
10.7
47
133
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
10.7
244
1536
M79.6
ICD-10 Finland
Pain in limb
1.4
10.7
559
4285
WX234
NOMESCO Finland
Paracervical blockade
4.2
10.7
39
94
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
+∞
10.4
10
*
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
10.4
10
*
6201A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Corpus luteum cyst or haematoma
+∞
10.4
10
*
6181A
ICD-9 Finland
Genital prolapse, Uterine prolapse without mention of vaginal wall prolapse
+∞
10.4
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.3
418
3035
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.8
10.2
65
240
1410
FHL
Laparoscopy
3.4
10.2
47
139
LCB98
NOMESCO Finland
Other transluminal endoscopic excision of lesion of uterus
40.3
10.0
12
*
R2110
NOMESCO Finland
Giving the first information
2.3
9.9
89
398
LEG10
NOMESCO Finland
Vaginal urethrocystopexy
3.0
9.9
56
190
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
7.0
9.8
23
33
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
8.8
9.8
20
23
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
6.6
9.7
24
37
J01FF01
ATC
clindamycin; systemic
1.5
9.6
390
2823
J01MA02
ATC
ciprofloxacin; systemic
1.4
9.6
525
4037
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
9.6
265
1756
1412
FHL
Laparoscopy and sterilization
1.8
9.5
166
965
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.3
9.5
84
373
09992
ICD-8 Finland
Other veneral disease, Condyloma acuminatum
7.6
9.4
21
28
M01AH05
ATC
etoricoxib; oral
1.4
9.4
914
7772
N83.9
ICD-10 Finland
Noninflammatory disorder of ovary, fallopian tube and broad ligament, unspecified
+∞
9.4
9
*
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
+∞
9.4
9
*
D25.0
ICD-10 Finland
Submucous leiomyoma of uterus
3.3
9.4
45
138
N94.4
ICD-10 Finland
Primary dysmenorrhoea
12.4
9.4
16
13
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
5.6
9.4
26
47
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
9.3
259
1718
8204
FHL
Salpingo-oophorectomy
5.3
9.2
27
52
C05AA08
ATC
fluocortolone; rectal, topical
1.7
9.2
205
1282
N05CF01
ATC
zopiclone; oral
1.4
9.1
501
3855
KCV04
NOMESCO Finland
Distension of bladder with fluid
5.9
9.1
24
41
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
15.7
9.0
14
9
N89.9
ICD-10 Finland
Noninflammatory disorder of vagina, unspecified
36.9
9.0
11
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
9.0
138
765
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
9.0
291
2003
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
9.0
80
356
G03DB01
ATC
dydrogesterone; oral
1.6
8.9
236
1545
B01AB05
ATC
enoxaparin; parenteral
1.4
8.8
469
3580
G04BD04
ATC
oxybutynin; oral, transdermal
2.1
8.8
94
454
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
14.1
8.7
14
10
R51.80
ICD-10 Finland
Headache
1.7
8.6
198
1247
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
8.6
106
544
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
8.6
486
3751
N91.1
ICD-10 Finland
Secondary amenorrhoea
16.4
8.5
13
8
WX320
NOMESCO Finland
Spinalanesthesy
1.5
8.5
320
2274
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.4
8.5
39
116
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.8
8.5
54
200
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
5.2
8.5
25
49
XKC03
NOMESCO Finland
Water cystometry
3.0
8.5
46
155
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
8.4
81
374
K30
ICD-10 Finland
Functional dyspepsia
1.7
8.4
158
940
J01MA12
ATC
levofloxacin; systemic
1.6
8.4
239
1596
6282A
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE PRIM]
+∞
8.3
8
*
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
+∞
8.3
8
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.2
8.3
41
129
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.2
392
2924
L03
ICPC
Low back symptom/complaint
1.5
8.2
361
2650
N06AA09
ATC
amitriptyline; systemic
1.7
8.2
158
945
18099
ICD-8 Finland
Malignant neoplasm of cervix uteri
14.5
8.2
13
9
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
8.2
153
909
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.2
1072
9460
N02AA05
ATC
oxycodone; systemic
1.6
8.1
201
1293
R03AC02
ATC
salbutamol; inhalant
1.3
8.1
796
6712
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.1
550
4373
JGC01
NOMESCO Finland
Laparoscopic rectopexy
8.2
8.1
17
21
1350
FHL
Hysteroscopy
9.0
8.0
16
18
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
8.0
322
2317
8114
FHL
Endometrial specimens (histological and cytological)
10.1
8.0
15
15
G03DC02
ATC
norethisterone; oral
1.6
8.0
231
1545
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
8.0
335
2432
H25.8
ICD-10 Finland
Other senile cataract
1.7
8.0
164
1000
XKD00
NOMESCO Finland
Uroflowmetry
2.4
7.9
64
270
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
7.9
181
1138
J01DA01
ATC
[U] cefalexin; systemic
1.3
7.8
964
8393
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
7.8
83
402
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.8
136
791
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
4.7
7.8
25
54
R15
ICD-10 Finland
Faecal incontinence
2.8
7.7
47
171
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.7
584
4716
G44.2
ICD-10 Finland
Tension-type headache
1.6
7.7
192
1236
LEF96
NOMESCO Finland
Other operation for prolapse of uterus or vaginal vault
45.2
7.7
9
*
LCA96
NOMESCO Finland
Other intrauterine operation
15.1
7.7
12
8
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.7
190
1222
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
7.6
154
936
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
25.1
7.6
10
*
SPAT1153
SPAT
Removal of sutures
1.4
7.5
464
3623
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
6.5
7.4
18
28
SPAT1301
SPAT
No procedures
1.4
7.4
465
3638
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.3
7.4
62
270
R35
ICD-10 Finland
Polyuria
2.4
7.4
59
251
LEF06
NOMESCO Finland
Anterior colporraphy with mesh for recurrent cystocele
+∞
7.3
7
*
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
+∞
7.3
7
*
6223A
ICD-9 Finland
Noninflammatory disorders of cervix, Old laceration of cervix
+∞
7.3
7
*
N85.6
ICD-10 Finland
Intrauterine synechiae
+∞
7.3
7
*
62310
ICD-8 Finland
Uterovaginal prolapse, Rectocele
+∞
7.3
7
*
6282B
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE SEC]
+∞
7.3
7
*
G04BD08
ATC
solifenacin; oral
2.0
7.2
93
484
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
7.2
146
888
23400
ICD-8 Finland
Neoplasm of unspecified nature of uterus, Carcinoma in situ of cervix uteri
15.8
7.2
11
7
7434
FHL
Abdominal urethrocystopexy
4.3
7.2
25
59
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
4.6
7.2
23
50
LEG12
NOMESCO Finland
Transobturatoric tape
3.3
7.2
34
105
R03BA05
ATC
fluticasone; inhalant
1.5
7.2
262
1850
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.1
699
5856
N94.1
ICD-10 Finland
Dyspareunia
20.1
7.1
10
5
LAF20
NOMESCO Finland
Unilateral transvaginal salpingo-oophorectomy
10.1
7.0
13
13
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.0
813
6972
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.9
128
757
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.8
6.8
41
149
A06AD11
ATC
lactulose; oral
1.6
6.8
187
1234
N92.5
ICD-10 Finland
Other specified irregular menstruation
4.5
6.8
22
49
R05FB02
ATC
cough suppressants and expectorants
1.3
6.8
616
5092
K59.01
ICD-10 Finland
Constipation outlet obstruction type
6.1
6.8
17
28
N03AX16
ATC
pregabalin; oral
1.4
6.8
337
2527
8341
FHL
Colony removal or incineration
40.2
6.8
8
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
6.7
36
122
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
7.2
6.7
15
21
A02BA02
ATC
ranitidine; systemic
1.5
6.7
271
1951
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.7
6.7
144
894
A63.0
ICD-10 Finland
Anogenital (venereal) warts
3.0
6.7
36
123
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
6.6
1448
13569
21900
ICD-8 Finland
Other benign neoplasm of uterus, Papiloma, polyp
4.2
6.6
23
55
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.6
620
5144
8221
FHL
Sterilization of the laparotomy pathway
2.1
6.6
67
321
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.5
199
1349
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.5
335
2526
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
6.9
6.5
15
22
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
1.6
6.5
158
1011
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.0
6.5
81
418
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.5
662
5557
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
6.5
108
621
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.4
354
2701
N93.0
ICD-10 Finland
Postcoital and contact bleeding
70.1
6.4
7
*
N96
ICD-10 Finland
Habitual aborter
70.1
6.4
7
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.4
664
5585
N89.8
ICD-10 Finland
Other specified noninflammatory disorders of vagina
14.4
6.4
10
7
J01FA09
ATC
clarithromycin; systemic
1.3
6.4
472
3777
WX110
NOMESCO Finland
Local anesthesy
1.3
6.3
1015
9044
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.3
345
2627
62200
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta
4.6
6.3
20
44
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
6.3
207
1426
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
+∞
6.3
6
*
62551
ICD-8 Finland
NA
+∞
6.3
6
*
62521
ICD-8 Finland
Other diseases of uterus, Hyperplasia glandularis cystica endometrii
+∞
6.3
6
*
N99.8
ICD-10 Finland
Other postprocedural disorders of genitourinary system
+∞
6.3
6
*
62550
ICD-8 Finland
NA
+∞
6.3
6
*
62670
ICD-8 Finland
Disorders of menstruation, Postmenopausal bleeding
+∞
6.3
6
*
SPAT1216
SPAT
Assessment of functional ability
1.5
6.2
223
1565
N03AX12
ATC
gabapentin; oral
1.5
6.2
209
1447
J01FA10
ATC
azithromycin; systemic
1.3
6.2
871
7622
8305
FHL
Supravaginal amputation or resection
3.0
6.1
33
113
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
6.1
298
2223
SPAT1211
SPAT
Application of soft bandage
1.7
6.1
127
781
8436
FHL
Vaginal hysterectomy and anterior cataract
12.6
6.1
10
8
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
3.7
6.1
24
65
SPAT1229
SPAT
Assessment of need for aid
1.7
6.0
118
710
Z54.0
ICD-10 Finland
Convalescence following surgery
4.4
6.0
20
46
JG1JB
NOMESCO Finland
Defekography with X-ray
6.7
6.0
14
21
L02AE01
ATC
buserelin; implant, nasal, parenteral
6.7
6.0
14
21
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
6.0
106
622

Mortality – FinRegistry

Association

Association between endpoint N14_OTHNONINFCERVIX and mortality.

Females

Parameter HR [95% CI] p-value
N14_OTHNONINFCERVIX 0.821 [0.73, 0.93] 0.002
Birth year 0.994 [0.99, 1.0] 0.173

During the follow-up period (1.1.1998 — 31.12.2019), 454 out of 4412 females with N14_OTHNONINFCERVIX died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_OTHNONINFCERVIX.

N-year risk Females Males
1 0.074% No data
5 0.516% No data
10 1.295% No data
15 2.378% No data
20 4.125% No data

Relationships between endpoints

Index endpoint: N14_OTHNONINFCERVIX – Other noninflammatory disorders of cervix uteri

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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