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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of retroperitoneum and peritoneum

C3_RETROPERITONEUM_PERITONEUM

retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C48
  • Cancer registry: Topography ICD-O-3 C48
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

267

4. Check minimum number of events

None

267

5. Include endpoints

None

267

6. Filter based on genotype QC (FinnGen only)

258

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 258 185 73
Unadjusted period prevalence (%) 0.06 0.07 0.03
Median age at first event (years) 67.81 67.42 68.79

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
267
Matched controls
2670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
206.3
307.4
152
17
WX302
NOMESCO Finland
Thoracal epidural anesthesy
120.3
230.1
120
18
A04AA01
ATC
ondansetron; systemic, rectal
65.3
200.7
118
32
A03FA01
ATC
metoclopramide; systemic, rectal
27.8
176.4
187
207
Z51.5
ICD-10 Finland
Palliative care
37.5
147.3
100
42
130
Kela drug reimbursment
Malignant tumour
+∞
145.5
126
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
25.3
136.4
112
74
JN4BD
NOMESCO Finland
Extensive body CT
25.7
123.9
98
59
B01AB10
ATC
tinzaparin; parenteral
14.2
87.9
97
103
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
1091.0
84.4
78
*
JN4AD
NOMESCO Finland
Body CT examination
17.3
83.1
77
61
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
81.5
74
*
C48.89
ICD-10 Finland
Overall malignant tumor of the peritoneum and retroperitoneum other or unspecified tumor
+∞
81.5
74
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
20.9
76.1
62
38
N02AA05
ATC
oxycodone; systemic
9.1
71.7
128
246
JAL30
NOMESCO Finland
Omentectomy
163.4
71.0
72
6
WW500
NOMESCO Finland
Blood transfusion
29.0
68.9
48
20
L03AA13
ATC
pegfilgrastim; parenteral
403.6
64.4
62
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
64.2
59
*
8461/3-C48.2
ICD-O-3
High grade serous carcinoma of peritoneum, NOS
+∞
64.2
59
*
R18
ICD-10 Finland
Ascites
100.6
63.6
68
9
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
61.9
57
*
KKB10
NOMESCO Finland
Excision of retroperitoneal tumour
+∞
60.8
56
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
55.1
51
*
TPH07
NOMESCO Finland
Cathetrisation of artery
8.4
54.9
90
153
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
14.1
54.2
54
47
C57.9
ICD-10 Finland
Malignant neoplasm: Female genital organ, unspecified
+∞
49.5
46
*
JAH00
NOMESCO Finland
Laparotomy
17.6
48.7
42
28
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
48.4
45
*
C48.02
ICD-10 Finland
Malignant tumor of the retroperitoneal space liposarcoma
+∞
48.4
45
*
L03AA02
ATC
filgrastim; parenteral
548.9
47.9
46
*
WX402
NOMESCO Finland
General anaesthesia
6.4
46.4
106
249
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
20.3
46.3
37
21
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
17.7
43.4
37
24
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
42.9
40
*
L02BG04
ATC
letrozole; oral
87.2
40.3
44
6
LCD00
NOMESCO Finland
Hysterectomy
9.7
40.3
52
65
B01AB05
ATC
enoxaparin; parenteral
5.2
40.3
155
559
C48.0
ICD-10 Finland
Malignant neoplasm: Retroperitoneum
+∞
39.6
37
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
38.5
36
*
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
+∞
37.4
35
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
68.8
36.4
41
7
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
11.6
36.3
40
40
JN3BD
NOMESCO Finland
Extensive abdominal CT
6.5
36.0
70
138
JEA00
NOMESCO Finland
Appendectomy
9.1
35.6
48
63
C48.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of retroperitoneum and peritoneum
+∞
34.1
32
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.5
32.7
78
185
JAL00
NOMESCO Finland
Biopsy of peritoneum
129.3
32.5
34
*
JAH01
NOMESCO Finland
Laparoscopy
10.4
32.0
38
42
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
31.9
30
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
125.0
31.4
33
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
30.8
29
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
30.8
29
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
30.8
29
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.7
30.5
67
147
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
338.7
30.5
30
*
C48.09
ICD-10 Finland
Malignant tumor of the retroperitoneal space other or unspecified tumor
+∞
29.7
28
*
ZX120
NOMESCO Finland
Intravenous
7.0
28.9
49
83
WZC00
NOMESCO Finland
Treatment plan or consultation
4.2
28.9
123
455
XX3DW
NOMESCO Finland
Time consuming IT work
7.7
27.6
42
63
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
103.9
26.2
28
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.1
25.8
64
155
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.3
25.1
85
263
TPX10
NOMESCO Finland
Implantation of vascular injection port
23.5
24.6
35
17
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
10.7
24.5
28
29
A04AD12
ATC
aprepitant; systemic
+∞
24.3
23
*
8461/3-C48.1
ICD-O-3
High grade serous carcinoma of specified parts of peritoneum
+∞
24.3
23
*
C45.1
ICD-10 Finland
Mesothelioma of peritoneum
+∞
24.3
23
*
A79
ICPC
Malignancy NOS
+∞
23.3
22
*
C48.00
ICD-10 Finland
Malignant tumor of the retroperitoneal space without histology
+∞
23.3
22
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
23.3
22
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
24.0
22.7
32
15
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
22.0
55
133
8858/3-C48.0
ICD-O-3
Dedifferentiated liposarcoma of retroperitoneum
+∞
21.1
20
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
21.1
20
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
119.4
20.9
22
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
215.3
19.8
20
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
19.7
96
373
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.8
19.0
71
231
C48.03
ICD-10 Finland
Malignant tumor of the retroperitoneal space leiomyosarcoma
+∞
19.0
18
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
107.7
18.8
20
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
107.7
18.8
20
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
23.8
18.6
26
12
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.2
18.2
33
59
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
17.9
17
*
C57.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of female genital organs
+∞
17.9
17
*
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
+∞
17.9
17
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
17.9
17
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
17.8
161
884
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
22.8
17.7
25
12
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.5
17.2
28
20
KAC10
NOMESCO Finland
Total nephrectomy with capsule
+∞
16.8
16
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
16.8
16
*
JAL01
NOMESCO Finland
Laparoscopic biopsy of peritoneum
+∞
16.8
16
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
16.8
16
*
8850/3-C48.0
ICD-O-3
Liposarcoma, NOS, of retroperitoneum
+∞
16.8
16
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
16.8
16
*
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
14.9
16.4
27
20
JFB00
NOMESCO Finland
Partial resection of small intestine
50.9
16.2
19
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
5.7
16.2
32
62
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
16.2
82
321
8890/3-C48.0
ICD-O-3
Leiomyosarcoma, NOS, of retroperitoneum
+∞
15.8
15
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
15.8
15
*
KAC00
NOMESCO Finland
Nephrectomy
+∞
15.8
15
*
JMA10
NOMESCO Finland
Transabdominal total splenectomy
169.5
15.6
16
*
JN4CD
NOMESCO Finland
Very extensive body CT
19.2
15.4
23
13
HA1AA
NOMESCO Finland
X-ray mammography
6.8
15.3
25
40
C48.2
ICD-10 Finland
Malignant neoplasm: Peritoneum, unspecified
+∞
14.7
14
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.5
14.6
25
42
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.9
14.3
94
423
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
17.0
14.2
22
14
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
25.4
14.0
19
8
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
13.1
13.9
24
20
C48.19
ICD-10 Finland
Malignant tumor in specified location in peritoneum other or unspecified histlogy
+∞
13.7
13
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
13.7
13
*
C56.00
ICD-10 Finland
Malignant tumor of the ovary without histology
+∞
13.7
13
*
C56
ICD-10 Finland
Malignant neoplasm of ovary
+∞
13.7
13
*
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
147.2
13.6
14
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
14.9
13.5
22
16
WF002
NOMESCO Finland
Radical radiotherapy
42.4
13.3
16
*
X77
ICPC
Malignant neopl genital female other
+∞
12.6
12
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
+∞
12.6
12
*
C48.29
ICD-10 Finland
Malignant tumor in unspecified localization in peritoneum other or unspecified histology
+∞
12.6
12
*
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
+∞
12.6
12
*
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
+∞
12.6
12
*
1510
Kela drug reimbursment
Niraparib
+∞
12.6
12
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
12.6
12
*
3009
Kela drug reimbursment
Niraparib
+∞
12.6
12
*
B01AB04
ATC
dalteparin; parenteral
5.3
12.4
26
53
A06AH03
ATC
naloxegol; oral
39.6
12.3
15
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
68.0
11.7
13
*
9050/3-C48.2
ICD-O-3
Mesothelioma, malignant of peritoneum, NOS
+∞
11.5
11
*
JAQ00
NOMESCO Finland
Extensive excision of peritoneum
+∞
11.5
11
*
389
Kela drug reimbursment
Olaparib
+∞
11.5
11
*
LAF16
NOMESCO Finland
Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer
+∞
11.5
11
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
11.5
11
*
1511
Kela drug reimbursment
Olaparib
+∞
11.5
11
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
11.5
11
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
11.5
11
*
C56.98
ICD-10 Finland
Malignant tumor of the ovary, indeterminate histology
+∞
11.5
11
*
115
Kela drug reimbursment
Breast cancer
+∞
11.5
11
*
C48.20
ICD-10 Finland
Malignant tumor in unspecified localization in the peritoneum without histology
+∞
11.5
11
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
11.5
11
*
JFF10
NOMESCO Finland
Loop enterostomy
+∞
11.5
11
*
L02BA01
ATC
tamoxifen; oral
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
L01XK02
ATC
niraparib; oral
+∞
11.5
11
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
11.5
56
211
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
11.5
120
666
WZC30
NOMESCO Finland
Teaching
3.3
11.2
48
167
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
11.0
115
636
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.5
10.8
41
132
D70.82
ICD-10 Finland
Drug-induced neutropenia
114.3
10.5
11
*
PJA12
NOMESCO Finland
Sentinel node biopsy
114.3
10.5
11
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
9.4
10.5
21
24
C48.1
ICD-10 Finland
Malignant neoplasm: Specified parts of peritoneum
+∞
10.5
10
*
9680/3-C48.0
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of retroperitoneum
+∞
10.5
10
*
159
Kela drug reimbursment
Pazopanib
+∞
10.5
10
*
C48.80
ICD-10 Finland
Overall malignant tumor of the peritoneum and retroperitoneum without histology
+∞
10.5
10
*
WC115
NOMESCO Finland
Cytostatic therapy of local tumor recidive with multiple drugs
+∞
10.5
10
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
10.5
10
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
34.0
10.4
13
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.2
10.1
28
72
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
41.7
10.0
12
*
JFB30
NOMESCO Finland
Right hemicolectomy
41.7
10.0
12
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
103.6
9.5
10
*
JFB43
NOMESCO Finland
Left hemicolectomy
103.6
9.5
10
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
+∞
9.4
9
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
9.4
9
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
8.8
9.2
19
23
ZX090
NOMESCO Finland
Other technic of radiotherapy
38.1
9.1
11
*
WX600
NOMESCO Finland
Single shot through catheter
38.1
9.1
11
*
SPAT1109
SPAT
Analgesia with portable analgesic pump
51.7
8.7
10
*
Z31.5
ICD-10 Finland
Genetic counselling
6.8
8.7
21
33
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
20.8
8.5
12
6
K56.7
ICD-10 Finland
Ileus, unspecified
13.3
8.5
14
11
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
92.9
8.5
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
8.4
115
694
L01XK01
ATC
olaparib; oral
+∞
8.4
8
*
9052/3-C48.2
ICD-O-3
Epithelioid mesothelioma, malignant of peritoneum, NOS
+∞
8.4
8
*
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
+∞
8.4
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
8.4
8
*
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
4.5
8.4
21
50
N02AX02
ATC
tramadol; systemic, rectal
2.1
8.1
132
847
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
34.5
8.1
10
*
S18
ICPC
Laceration/cut
2.1
8.1
135
874
R4190
NOMESCO Finland
Nutritional therapy
8.2
8.0
17
22
JFB46
NOMESCO Finland
Resection of sigmoid colon
13.6
8.0
13
10
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
15.6
7.8
12
8
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
46.4
7.8
9
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
46.4
7.8
9
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.1
7.7
18
27
C03CA01
ATC
furosemide; systemic
2.1
7.5
105
632
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
11.3
7.4
13
12
C49.43
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the abdomen leiomyosarcoma
+∞
7.3
7
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
D74
ICPC
Malignant neoplasm stomach
+∞
7.3
7
*
JLC10
NOMESCO Finland
Distal pancreatectomy
+∞
7.3
7
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
7.3
7
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
7.2
41
167
B03XA02
ATC
darbepoetin alfa; parenteral
10.4
7.1
13
13
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
10.4
7.1
13
13
SPAT1255
SPAT
Intravenous administration of medicine
3.4
7.1
26
82
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.1
7.0
18
31
A02BC02
ATC
pantoprazole; systemic
2.2
7.0
197
1513
XX1XW
NOMESCO Finland
Extensive written report from radiologist
8.6
6.9
14
17
R4110
NOMESCO Finland
Physiotherapy
2.1
6.9
81
455
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
11.4
6.9
12
11
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
41.1
6.8
8
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
41.1
6.8
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
6.7
31
112
XX2RW, ,
NOMESCO Finland
23.2
6.7
9
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.4
6.6
12
12
TJA10
NOMESCO Finland
Laparocentesis
71.5
6.5
7
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
6.8
6.4
15
23
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
6.3
6
*
C57.0
ICD-10 Finland
Malignant neoplasm: Fallopian tube
+∞
6.3
6
*
C48.22
ICD-10 Finland
Malignant tumor in unspecified localization in peritoneum liposarcoma
+∞
6.3
6
*
L01CB01
ATC
etoposide; systemic
+∞
6.3
6
*
WZC15, ,
NOMESCO Finland
+∞
6.3
6
*
1XC07, ,
NOMESCO Finland
+∞
6.3
6
*
343
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
C49.42
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the abdomen liposarcoma
+∞
6.3
6
*
8460/3-C48.2
ICD-O-3
Low grade serous carcinoma of peritoneum, NOS
+∞
6.3
6
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
6.3
6
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
C48.10
ICD-10 Finland
Malignant tumor in specified location in the peritoneum without histology
+∞
6.3
6
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
6.3
6
*
P20
ICPC
Memory disturbance
0.2
6.2
7
305
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.9
6.2
18
48
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
12.9
6.1
10
8
Z51.88
ICD-10 Finland
Other specified medical care
6.3
6.1
15
25
UJF32
NOMESCO Finland
Coloscopy
2.0
6.0
78
451

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
108
53
33.54
150.42
1.5
1.3
—
—
—
0
0
129
106
22.61
141.00
2.6
1.4
2.88
2.53
ug/l
0.39
85
87
69
12
77.19
126.16
1.4
1.0
—
—
—
0
0
72
48
20.17
85.20
2.4
1.7
158.18
13.38
u/ml
0.55
62
39
158
526
5.91
46.76
4.9
3.6
—
—
—
0
0
195
905
5.28
35.30
9.4
3.3
31.92
35.57
g/l
11.10
190
837
151
592
4.57
33.77
3.6
1.9
—
—
—
0
0
194
936
4.92
32.32
4.0
2.2
—
—
—
0
0
219
1161
5.93
32.27
27.2
5.9
4.08
4.27
e9/l
0.45
190
1016
77
188
5.35
31.11
2.8
2.1
36.01
30.45
u/l
0.89
69
156
68
149
5.78
31.01
9.2
5.8
—
—
—
0
0
124
465
4.11
28.46
3.5
1.8
—
—
—
0
0
194
1058
4.05
24.34
11.6
14.0
1.10
1.30
inr
3.96
51
295
91
302
4.05
24.27
1.9
1.8
—
—
—
0
0
80
246
4.22
23.65
8.8
5.2
0.05
1.74
mmol/l
4.26
68
203
61
155
4.80
23.03
2.0
2.0
0.20
0.21
g/l
0.45
54
138
57
141
4.87
22.19
1.4
1.1
—
—
—
0
0
116
480
3.50
21.89
19.6
4.5
—
—
—
0
0
142
693
3.24
19.99
2.7
1.6
—
—
—
0
0
43
93
5.32
19.47
9.7
6.1
—
—
—
0
0
123
582
3.06
17.78
3.5
2.8
—
—
—
0
0
123
597
2.97
16.77
3.6
2.9
0.74
0.53
e6/l
0.45
87
453
181
1100
3.00
15.94
8.8
4.8
1.19
1.22
mmol/l
5.36
156
951
144
776
2.86
15.93
6.3
3.5
65.05
118.69
e6/l
0.51
103
546
165
957
2.90
15.82
6.8
5.3
—
—
—
0
0
84
340
3.15
15.65
3.1
2.8
4.16
3.18
e6/l
0.35
39
183
127
648
2.83
15.48
3.6
2.9
51.26
152.67
e6/l
0.49
93
502
134
707
2.80
15.26
9.0
2.0
2.35
2.36
mmol/l
0.34
126
578
62
213
3.49
15.05
3.1
1.9
7.00
5.96
umol/l
0.34
57
176
163
970
2.75
14.37
6.3
5.3
8.98
8.55
%
0.80
153
901
125
653
2.72
14.28
4.6
2.9
7.39
7.40
ph
0.30
28
102
165
992
2.74
14.18
6.6
5.2
23.89
27.88
%
2.91
156
925
69
267
3.14
13.71
2.0
2.3
19.86
23.46
%
1.67
59
224
92
418
2.83
13.69
6.5
2.2
2.53
2.44
mmol/l
6.10
84
358
157
935
2.65
13.53
6.2
5.0
0.55
0.69
%
2.85
148
861
227
1638
3.58
13.51
17.8
5.0
99.90
75.97
u/l
3.75
222
1489
171
1064
2.69
13.43
6.6
4.9
2.07
1.86
e9/l
0.20
139
935
169
1047
2.67
13.37
6.2
4.8
0.03
0.04
e9/l
3.65
136
901
160
967
2.63
13.29
6.3
5.0
2.15
2.90
%
4.38
152
893
168
1040
2.66
13.27
6.2
4.8
0.67
0.58
e9/l
2.56
136
894
162
986
2.64
13.25
6.4
5.0
60.38
57.44
%
1.53
153
917
94
445
2.72
12.80
2.6
2.3
9.84
5.65
e6/l
1.52
82
403
60
222
3.20
12.79
9.9
5.2
97.58
94.69
%
6.38
60
214
210
1475
2.98
12.57
6.6
4.6
330.50
2627.30
e6/l
—
6
20
48
157
3.51
12.45
5.9
5.0
8.20
9.73
mmol/l
0.97
48
146
171
1089
2.59
12.40
6.4
5.1
0.16
0.19
e9/l
0.98
141
947
126
706
2.49
11.91
3.4
2.0
152.70
61.83
u/l
0.49
118
636
130
762
2.38
10.85
4.1
3.3
—
—
—
0
0
21
24
9.40
10.49
2.6
1.5
2.85
160.27
u/ml
0.50
21
24
94
485
2.45
10.36
1.5
1.4
—
—
—
0
0
189
2286
0.41
9.41
4.2
5.4
2.71
2.74
mmol/l
0.13
170
2088
181
2221
0.43
9.06
3.8
4.7
1.44
1.54
mmol/l
2.52
162
2027
13
8
16.99
8.64
2.9
1.3
—
—
—
0
0
185
2237
0.44
8.32
3.8
4.7
4.64
4.69
mmol/l
0.26
169
2049
172
2132
0.46
8.10
5.4
6.3
41.09
40.33
mmol/mol
0.54
164
1965
160
1111
2.10
7.91
10.2
5.1
0.00
0.00
estimate
-0.00
32
181
140
929
2.07
7.78
14.0
7.9
0.01
0.00
e9/l
0.63
105
751
160
1121
2.07
7.60
7.2
3.8
0.00
0.00
estimate
-0.00
33
180
11
7
16.31
7.29
1.0
1.0
—
—
—
0
0
90
530
2.05
6.73
7.6
3.7
—
—
—
0
0
83
475
2.08
6.70
2.1
1.6
1.73
1.19
mg/l
1.86
74
374
198
1541
2.10
6.58
8.2
4.4
—
—
—
0
0
11
10
11.41
6.35
1.9
1.1
—
—
—
0
0
44
198
2.46
6.28
2.0
3.4
112.97
240.58
ng/l
2.51
36
183
76
431
2.07
6.23
3.6
3.9
138.83
132.24
ng/l
0.02
65
339
178
2131
0.51
6.06
3.6
4.2
1.36
1.29
mmol/l
0.99
158
1920
150
1104
1.82
5.39
7.3
3.8
0.00
0.01
estimate
0.50
33
199
10
11
9.39
5.33
2.5
1.0
—
—
—
0
0
127
895
1.80
5.22
7.0
3.5
5.50
5.94
ph
—
7
50
43
208
2.27
5.21
2.9
2.9
1.23
2.37
mmol/l
1.23
35
176
194
2233
0.52
5.02
4.5
4.8
6.10
6.00
mmol/l
0.46
180
2014
73
438
1.92
4.99
2.9
2.7
489.24
525.89
mosm/kgh2o
0.92
59
377
85
539
1.85
4.88
2.0
2.2
2.32
3.22
mg/l
3.63
72
451
15
43
3.64
4.68
3.2
3.8
3.42
3.03
mmol/l
—
9
29
194
1589
1.81
4.44
4.3
3.9
—
—
—
0
0
13
29
4.66
4.30
3.9
2.6
7.95
156.47
u/l
—
6
11
7
6
11.93
4.30
1.0
1.0
—
—
—
0
0
34
630
0.47
4.14
1.4
1.6
1.34
1.35
mmol/l
0.03
29
527
14
43
3.38
3.96
1.5
2.7
—
—
—
0
0
46
259
1.94
3.73
4.8
3.8
1.06
1.00
mmol/l
0.84
46
237
9
16
5.78
3.69
1.1
1.1
—
—
—
0
0
183
2095
0.60
3.55
4.8
5.0
2.19
1.98
mu/l
1.18
168
1901
147
1768
0.62
3.47
4.3
4.1
14.54
14.94
pmol/l
1.17
139
1596
11
27
4.20
3.43
5.3
3.0
60.18
57.41
%
0.27
11
27
11
27
4.20
3.43
5.0
2.3
4.55
4.61
e9/l
0.03
11
27
8
14
5.85
3.36
1.3
1.7
—
—
—
0
0
34
180
2.02
3.28
1.3
2.1
55.99
64.47
e9/l
0.63
15
141
10
24
4.29
3.23
1.0
1.1
—
—
—
0
0
47
732
0.57
3.16
2.8
3.2
—
—
—
0
0
11
31
3.66
3.03
1.6
2.0
55.36
65.62
%
0.52
11
31
5
5
10.15
2.99
1.2
1.2
—
—
—
0
0
20
400
0.46
2.93
1.1
1.3
25.53
14.16
u/ml
—
6
143
18
77
2.43
2.89
5.4
1.9
602.50
339.38
ug/l
0.45
18
72
32
175
1.94
2.83
8.1
3.3
—
—
—
0
0
28
150
1.97
2.63
5.8
4.2
—
—
—
0
0
6
12
5.09
2.41
1.0
1.9
10.87
12.33
%
—
6
12
11
39
2.90
2.37
1.5
2.8
—
—
—
0
0
33
194
1.80
2.36
5.3
3.0
—
—
—
0
0
21
106
2.06
2.33
1.8
2.2
0.58
0.64
%
0.30
21
106
26
143
1.91
2.28
3.3
4.0
1.33
0.69
%
0.89
18
34
27
151
1.88
2.26
8.9
6.1
24.38
25.08
mmol/l
0.70
27
146
9
29
3.17
2.24
2.3
1.2
—
—
—
0
0
5
9
5.64
2.22
1.0
1.2
—
—
—
0
0
24
130
1.93
2.21
3.4
4.2
1.25
0.24
%
1.91
16
29
8
24
3.40
2.20
1.4
1.8
92.39
90.78
%
—
8
24
237
2188
1.74
2.18
32.3
12.1
46.53
21.98
mg/l
15.33
228
1698
21
109
2.01
2.17
1.0
1.3
—
—
—
0
0
21
110
1.99
2.12
1.8
2.1
1.30
1.12
%
0.41
21
110
5
145
0.33
2.09
1.2
1.3
—
—
—
0
0
14
63
2.29
2.04
2.5
1.7
—
—
—
0
0
5
11
4.61
1.95
4.4
2.0
—
—
—
0
0
24
136
1.84
1.95
3.5
4.2
0.25
0.07
%
0.58
16
27
13
58
2.30
1.94
4.7
3.4
—
—
—
0
0
18
93
2.00
1.90
6.1
4.5
—
—
—
0
0
28
168
1.74
1.89
1.2
1.5
—
—
—
0
0
8
28
2.91
1.87
2.6
1.2
—
—
nmol/l
—
0
0
5
12
4.22
1.83
1.2
1.1
—
—
—
0
0
14
67
2.15
1.79
7.1
5.2
1.61
1.27
mmol/l
0.64
14
61
76
589
1.41
1.68
7.9
3.9
0.00
0.00
estimate
-0.00
34
178
32
208
1.61
1.63
1.2
1.5
—
—
—
0
0
5
14
3.62
1.62
1.4
5.2
—
—
—
0
0
108
895
1.35
1.57
2.3
2.6
231.61
104.59
ug/l
3.59
102
816
5
127
0.38
1.54
1.0
1.2
649.94
222.52
u/ml
—
5
115
0
45
0.00
1.51
0.0
1.1
—
—
—
0
0
35
240
1.53
1.44
1.9
1.7
—
—
—
0
0
75
595
1.36
1.42
5.4
3.4
—
—
—
0
0
21
128
1.70
1.38
3.8
4.3
0.00
0.04
%
0.48
13
24
34
474
0.68
1.32
1.7
1.7
1192.54
1141.17
nmol/l
0.12
27
354
152
1357
1.28
1.18
4.5
3.0
67.12
46.25
u/l
1.04
140
1244
0
33
0.00
1.17
0.0
1.2
—
—
—
0
0
5
20
2.53
1.15
4.4
2.1
—
—
—
0
0
5
20
2.53
1.15
1.6
3.4
—
—
—
0
0
18
115
1.61
1.02
1.3
1.3
—
—
—
0
0
65
784
0.77
1.01
3.6
3.8
13.14
7.41
mg/mmol
0.60
44
472
6
117
0.50
0.96
1.3
1.6
—
—
—
0
0
8
143
0.55
0.96
1.4
1.4
—
—
—
0
0
57
689
0.78
0.89
3.6
3.8
—
—
—
0
0
68
575
1.25
0.80
2.9
2.2
6285.36
10199.42
umol/l
0.26
61
495
35
271
1.34
0.79
1.7
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.7
—
—
—
0
0
0
26
0.00
0.79
0.0
3.0
—
—
—
0
0
10
60
1.69
0.73
1.3
1.2
—
—
—
0
0
41
330
1.29
0.72
1.1
1.1
—
—
—
0
0
5
26
1.94
0.71
1.4
1.3
—
—
—
0
0
23
170
1.39
0.70
1.2
1.2
—
—
—
0
0
5
93
0.53
0.68
1.6
1.2
—
—
—
0
0
5
29
1.74
0.64
1.0
1.3
—
—
—
0
0
12
175
0.67
0.63
1.8
1.4
—
—
—
0
0
89
991
0.85
0.61
2.0
2.1
86.61
94.96
pmol/l
0.95
48
467
6
35
1.73
0.58
1.0
1.1
—
—
—
0
0
6
36
1.68
0.57
4.5
2.3
—
—
—
0
0
66
750
0.84
0.57
2.8
3.2
568.88
310.06
mg/l
0.21
44
462
238
2311
1.27
0.56
40.4
14.9
138.54
139.84
mmol/l
9.75
232
2242
68
767
0.85
0.53
2.8
3.1
5.67
6.89
mmol/l
2.64
54
628
238
2318
1.25
0.49
40.3
14.9
3.98
3.98
mmol/l
0.04
232
2246
17
220
0.76
0.47
1.5
1.7
—
—
—
0
0
12
161
0.73
0.42
2.8
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
28.09
—
0
11
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
5
36
1.40
0.38
1.0
1.5
—
—
—
0
0
30
255
1.20
0.36
1.4
1.7
—
—
—
0
0
5
76
0.65
0.36
1.2
1.1
—
—
—
0
0
13
166
0.77
0.34
1.2
1.3
—
—
—
0
0
239
2432
0.84
0.34
54.7
18.4
120.27
134.57
g/l
33.48
233
2379
56
505
1.14
0.33
6.7
4.0
1.02
1.02
kg/l
—
7
74
6
87
0.68
0.33
1.2
1.2
—
0.27
—
0
8
239
2431
0.84
0.33
54.0
18.2
91.69
91.20
fl
0.75
233
2379
239
2431
0.84
0.33
54.2
18.3
4.13
4.47
e12/l
17.48
227
2342
239
2431
0.84
0.33
53.9
18.2
30.10
30.26
pg
0.63
233
2379
239
2430
0.84
0.31
54.6
18.3
271.82
252.00
e9/l
3.23
228
2349
239
2430
0.84
0.31
54.2
18.3
7.26
6.63
e9/l
1.21
228
2341
11
142
0.76
0.31
3.5
3.6
—
—
—
0
0
239
2429
0.85
0.30
55.7
18.2
36.72
39.87
%
16.18
221
2244
5
74
0.67
0.26
3.2
4.4
—
—
—
0
0
5
74
0.67
0.26
2.8
1.4
36.34
31.79
mg/l
—
5
65
5
74
0.67
0.26
2.8
1.4
43.10
43.03
mg/l
—
5
65
5
75
0.66
0.26
1.0
1.9
—
—
—
0
0
98
926
1.09
0.26
3.2
3.6
68.89
69.47
ng/l
0.00
75
675
27
305
0.87
0.23
1.3
1.4
320.00
592.86
titre
—
6
84
15
178
0.83
0.22
1.5
1.5
—
—
—
0
0
44
479
0.90
0.22
1.2
1.3
0.92
1.59
u/ml
0.73
12
138
0
10
0.00
0.21
0.0
1.2
—
108.35
—
0
10
0
10
0.00
0.21
0.0
5.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
39.92
—
0
6
0
13
0.00
0.21
0.0
1.7
—
7.52
—
0
8
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
123.22
—
0
9
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
1198016.25
—
0
8
10
121
0.82
0.18
3.0
3.6
—
7.41
—
0
16
5
66
0.75
0.17
3.2
2.2
1.58
1.50
mmol/l
—
5
66
8
71
1.13
0.16
3.3
4.5
23.09
25.40
mmol/l
—
8
66
11
130
0.84
0.16
2.5
2.4
—
—
—
0
0
9
81
1.11
0.15
1.2
1.2
—
—
—
0
0
37
397
0.92
0.14
2.0
1.3
2.39
2.56
g/l
0.27
24
227
20
221
0.90
0.13
5.3
3.4
—
—
—
0
0
61
585
1.06
0.11
1.7
1.5
19.74
21.49
nmol/l
0.55
56
496
5
46
1.09
0.09
1.0
1.2
1.04
1.02
nmol/l
—
5
36
6
54
1.11
0.09
1.5
1.2
—
—
—
0
0
5
62
0.80
0.08
3.2
2.2
6.48
7.41
mmol/l
—
5
62
7
66
1.06
0.08
2.7
3.0
—
—
—
0
0
14
152
0.92
0.06
2.1
2.9
—
—
—
0
0
237
2359
1.04
0.04
25.2
8.9
25.99
24.23
u/l
0.86
230
2255
51
520
0.98
0.02
1.9
1.7
452.21
449.12
pmol/l
0.02
42
416
25
257
0.97
0.01
1.9
1.8
109.09
129.75
ug/g
0.21
20
199
229
2283
1.02
0.01
26.9
12.0
—
—
—
0
0
23
228
1.01
0.00
1.2
1.3
—
—
—
0
0
46
462
0.99
0.00
3.8
3.8
1.76
2.08
ug/l
0.53
41
418
167
1674
0.99
0.00
3.2
4.2
22.05
12.92
mm/h
4.94
156
1515
10
96
1.04
0.00
2.4
2.2
—
—
—
0
0
6
62
0.97
-0.00
2.5
2.0
8.85
12.04
mg/l
—
6
57
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
233
2330
1.00
-0.00
46.3
14.5
78.63
75.73
umol/l
0.88
233
2330
8
81
0.99
-0.00
1.6
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
21.9
—
1747.33
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
157.08
—
0
6
0
9
0.00
-0.00
0.0
12.6
—
969.00
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
-0.00
2.9
3.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.6
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.8
3.57
5.09
mmol/24h
—
5
44
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.1
—
26.86
—
0
7
0
5
0.00
-0.00
0.0
7.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2.73
—
0
6
7
74
0.94
-0.00
1.9
1.2
34.16
37.59
g/l
—
7
63
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.9
—
37255.56
—
0
9
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
19.42
—
0
6
0
9
0.00
-0.00
0.0
7.2
—
0.62
—
0
9

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_RETROPERITONEUM_PERITONEUM – Malignant neoplasm of retroperitoneum and peritoneum

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).