No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
972 |
4. Check minimum number of eventsNone |
972 |
5. Include endpointsNone |
972 |
6. Filter based on genotype QC (FinnGen only) |
921 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H18
- Name in latin
- Keratoconus
Similar endpoints
↥List of similar endpoints to
Keratoconus
based on the number of shared cases.
Similar with more cases:
- Other disorders of cornea
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7756 | 2530 | 5162 |
| Only index persons | 7472 | 2441 | 5031 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.07 | 0.14 |
| Only index persons | 0.16 | 0.09 | 0.19 |
| Median age at first event (years) | |||
| Whole population | 36.99 | 41.37 | 34.91 |
| Only index persons | 36.87 | 41.09 | 34.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 921 | 399 | 522 |
| Unadjusted period prevalence (%) | 0.20 | 0.14 | 0.24 |
| Median age at first event (years) | 41.48 | 44.15 | 39.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 972
- Matched controls
- 9720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H18.6
ICD-10 Finland
Keratoconus
4503599627370496.0
307.7
951
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
11.1
233.9
295
367
WX100
NOMESCO Finland
Conjunctival surface anesthesia
10.9
228.0
291
367
CG2T4
NOMESCO Finland
Topography assessment of cornea
320.9
227.9
223
9
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
226.1
208
*
CGG11
NOMESCO Finland
Corneal cross-linking
+∞
177.7
165
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
155.5
145
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.3
145.1
598
2255
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
333.0
143.6
142
5
H52.2
ICD-10 Finland
Astigmatism
19.5
140.8
113
65
TCG10
NOMESCO Finland
Removal of sutures from cornea
707.1
128.6
124
*
H16.0
ICD-10 Finland
Corneal ulcer
17.4
124.1
105
67
Z3229
NOMESCO Finland
Other healthcare associate professional
6.8
106.7
189
333
WX140
NOMESCO Finland
Parabulbar anesthesy
10.1
102.7
123
137
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
964.8
91.3
88
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.4
82.2
187
413
ZXA10
NOMESCO Finland
Bilateral
4.2
79.9
274
837
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
78.2
74
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.5
76.7
402
1627
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.3
75.0
232
654
XCK10
NOMESCO Finland
Photography of fundus of eye
5.2
72.5
169
379
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
71.4
276
910
S01BA04
ATC
prednisolone; ophthalmic
16.9
69.8
59
37
CGD40
NOMESCO Finland
Implantation of intracorneal ring segments
+∞
66.4
63
*
WX002
NOMESCO Finland
Sedation and analgesia
3.5
60.0
270
972
S01BA01
ATC
dexamethasone; ophthalmic
9.1
58.7
74
87
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.5
54.9
114
229
H16.9
ICD-10 Finland
Keratitis, unspecified
121.0
53.4
57
5
3604
FHL
Penetration of the cornea
+∞
51.5
49
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.1
50.7
271
1071
CGD99
NOMESCO Finland
Other operation for error of refraction
+∞
49.4
47
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.2
48.8
144
385
ZXA05
NOMESCO Finland
Left side
2.9
46.8
293
1257
S01ED01
ATC
timolol; ophthalmic
9.4
46.7
57
64
H26.2
ICD-10 Finland
Complicated cataract
17.2
45.5
38
23
37103
ICD-8 Finland
Corneal opacity, Keratoconus
+∞
45.2
43
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
98.7
43.2
47
5
ZXA00
NOMESCO Finland
Right side
2.7
40.1
301
1403
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.0
38.8
87
186
H26.4
ICD-10 Finland
After-cataract
4.5
38.6
100
241
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
37.7
36
*
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
381.3
37.3
37
*
S01AD03
ATC
aciclovir; ophthalmic
6.8
36.1
58
90
H18.7
ICD-10 Finland
Other corneal deformities
+∞
35.6
34
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
35.6
34
*
H18.4
ICD-10 Finland
Corneal degeneration
181.3
33.9
35
*
CG2S4
NOMESCO Finland
Photography of cornea
124.5
33.9
36
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
32.5
31
*
S01EA05
ATC
brimonidine; ophthalmic
10.1
32.3
37
38
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
31.6
206
883
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
29.3
28
*
ZXD20
NOMESCO Finland
Day surgery
2.8
28.4
165
665
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
+∞
28.3
27
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.4
27.8
249
1233
Z3231
NOMESCO Finland
Registered nurse
2.2
26.4
293
1583
CGF10
NOMESCO Finland
Suture of laceration of cornea
+∞
25.1
24
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
24.6
374
2268
D11AH01
ATC
tacrolimus; topical
9.6
24.5
29
31
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
6.4
23.8
40
65
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
89.0
23.8
26
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
128.2
23.7
25
*
S01AX11
ATC
[U] ofloxacin
4.9
22.9
51
108
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
22.7
350
2120
XCK00
NOMESCO Finland
Perimetry
3.9
22.2
67
180
H18.2
ICD-10 Finland
Other corneal oedema
+∞
22.0
21
*
S01EC01
ATC
acetazolamide; systemic
7.3
21.7
32
45
H18.8
ICD-10 Finland
Other specified disorders of cornea
117.7
21.7
23
*
H26.02
ICD-10 Finland
Presenil cataract
5.3
21.6
44
86
L20.0
ICD-10 Finland
Besnier prurigo
2.9
20.8
107
401
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
214.4
20.7
21
*
S01FA01
ATC
atropine; ophthalmic
30.8
20.6
27
9
ZXE00
NOMESCO Finland
One hour or less
1.9
20.0
377
2423
H16.8
ICD-10 Finland
Other keratitis
107.2
19.6
21
*
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
6.5
18.9
31
49
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
21.3
18.7
27
13
H16.2
ICD-10 Finland
Keratoconjunctivitis
102.0
18.6
20
*
3606
FHL
Keratophakic corneal surgery
+∞
17.8
17
*
S01AA12
ATC
tobramycin; ophthalmic
96.9
17.6
19
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
96.9
17.6
19
*
S01EA03
ATC
apraclonidine; ophthalmic
19.0
17.4
26
14
CGG20
NOMESCO Finland
Epikeratofakia or keratofakia
+∞
16.7
16
*
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
16.7
16
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
16.6
113
487
D07AA02
ATC
hydrocortisone; topical
2.2
16.2
164
837
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.9
16.1
77
277
S01ED51
ATC
timolol, combinations; ophthalmic
3.1
15.7
66
220
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
15.7
15
*
CGG30
NOMESCO Finland
Anterior lamellar transplantation of cornea
+∞
15.7
15
*
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
152.2
14.5
15
*
S01BC03
ATC
diclofenac; ophthalmic
5.3
14.4
29
56
S01BA07
ATC
fluorometholone; ophthalmic
5.3
14.0
28
54
CFD10
NOMESCO Finland
Repair of conjunctiva
76.2
13.6
15
*
E000001, ,
ATC
1.9
13.3
198
1156
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
40.7
13.2
16
*
H18.0
ICD-10 Finland
Corneal pigmentations and deposits
+∞
12.5
12
*
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
131.6
12.5
13
*
H02AB06
ATC
prednisolone; systemic
1.6
12.4
423
3109
9881
FHL
Bandage replacement, suture or spike removal, or the like in an operating room or anesthesia
38.1
12.2
15
*
S01BC05
ATC
ketorolac; ophthalmic
4.0
11.9
34
88
S01AA01
ATC
chloramphenicol; ophthalmic
3.0
11.9
54
189
S01EE01
ATC
latanoprost; ophthalmic
3.2
11.8
48
157
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
11.5
11
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
11.5
11
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.2
11.0
21
21
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
13.1
10.7
18
14
L04AD01
ATC
ciclosporin; systemic
4.4
10.6
26
60
H17.8
ICD-10 Finland
Other corneal scars and opacities
111.2
10.4
11
*
Z96.7
ICD-10 Finland
Presence of other bone and tendon implants
+∞
10.4
10
*
L20
ICD-10 Finland
Atopic dermatitis
3.2
10.1
39
124
CD2S4
NOMESCO Finland
Photography of eye
11.4
10.1
18
16
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
40.5
10.0
12
*
E000002, ,
ATC
2.0
9.8
109
574
H02AB04
ATC
methylprednisolone; systemic
1.9
9.7
126
700
E0000UV, ,
ATC
1.6
9.6
367
2725
CKD60
NOMESCO Finland
Anterior vitrectomy
13.8
9.2
15
11
S01GX08
ATC
ketotifen; ophthalmic
2.7
9.1
50
194
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
9.0
258
1788
XCH00
NOMESCO Finland
Eye pressure measurement
3.0
9.0
39
133
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.0
8.9
99
521
CS494
NOMESCO Finland
Other visual field testing
3.7
8.8
27
74
S01EE05
ATC
tafluprost; ophthalmic
3.4
8.7
31
94
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
27.8
8.5
11
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
90.8
8.4
9
*
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
4.7
8.4
19
41
E66.8
ICD-10 Finland
Other obesity
2.3
8.4
60
265
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
+∞
8.3
8
*
CGE10
NOMESCO Finland
Keratectomy
+∞
8.3
8
*
D11AX14
ATC
[U] tacrolimus
9.5
8.3
16
17
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.3
8.2
63
286
D07AB08
ATC
desonide; topical
1.9
8.2
102
557
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.1
8.2
34
113
S01EE03
ATC
bimatoprost; ophthalmic
4.4
8.2
20
46
S01XA18
ATC
ciclosporin; ophthalmic
11.8
8.1
14
12
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
10.1
8.0
15
15
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.5
7.9
49
202
L04AA01
ATC
[U] ciclosporin
6.7
7.9
19
29
S01EX03, ,
ATC
8.5
7.8
16
19
D11AH02
ATC
pimecrolimus; topical
10.9
7.8
14
13
H27.0
ICD-10 Finland
Aphakia
15.2
7.7
12
8
H57.1
ICD-10 Finland
Ocular pain
2.9
7.7
36
129
Z2221
NOMESCO Finland
Medical doctor
1.6
7.6
231
1614
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
80.7
7.4
8
*
R03BA05
ATC
fluticasone; inhalant
1.7
7.3
161
1040
CDW99
NOMESCO Finland
Other operation on eyeball
+∞
7.3
7
*
CGD00
NOMESCO Finland
Keratotomy for error of refraction
+∞
7.3
7
*
CGW99
NOMESCO Finland
Other operation on cornea or sclera
+∞
7.3
7
*
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
7.3
7
*
H18.3
ICD-10 Finland
Changes in corneal membranes
+∞
7.3
7
*
S01GX05
ATC
lodoxamide; ophthalmic
4.5
7.2
17
38
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
30.2
7.2
9
*
S01AX12
ATC
[U] norfloxacin
12.1
7.1
12
10
J05AB01
ATC
aciclovir; systemic
1.6
7.1
181
1214
S01EC04
ATC
brinzolamide; ophthalmic
3.2
7.0
27
86
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
7.0
165
1084
A46
ICD-10 Finland
Erysipelas
1.8
7.0
116
694
D07AC01
ATC
betamethasone; topical
1.5
7.0
305
2298
114
Kela drug reimbursment
Glaucoma
2.3
6.9
52
235
S01FA02
ATC
scopolamine; ophthalmic
13.9
6.9
11
8
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
40.3
6.8
8
*
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
40.3
6.8
8
*
127
Kela drug reimbursment
Transplant complication
3.5
6.7
22
63
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.7
665
5816
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
6.7
115
696
R06AX27
ATC
desloratadine; oral
1.5
6.6
264
1950
N05BB01
ATC
hydroxyzine; systemic
2.1
6.6
59
286
J45
ICD-10 Finland
Asthma
1.9
6.5
87
487
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.5
216
1535
CGF20
NOMESCO Finland
Suture of laceration of cornea with plastic repair of conjunctiva
70.3
6.4
7
*
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
6.6
6.3
15
23
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.5
6.3
21
61
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
6.3
84
471
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
6.3
6
*
37102
ICD-8 Finland
Corneal opacity, Dystrophia corneae hereditaria
+∞
6.3
6
*
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
+∞
6.3
6
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
6.3
6
*
CJA10
NOMESCO Finland
Implantation of phakic lens in posterior chamber
+∞
6.3
6
*
37108
ICD-8 Finland
Corneal opacity, Alia definita
+∞
6.3
6
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
6.3
6
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
6.2
87
494
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
390
2952
1.54
9.30
5.1
5.1
36.45
36.53
g/l
0.10
359
2772
774
7035
1.49
5.84
4.7
4.3
1.91
2.19
mu/l
0.61
710
6543
332
2636
1.39
5.44
1.9
1.8
91.34
97.26
pmol/l
1.49
183
1413
850
7968
1.53
4.64
15.4
13.5
139.69
139.69
mmol/l
0.00
833
7775
852
8003
1.52
4.47
15.6
13.5
3.96
3.96
mmol/l
0.11
836
7796
642
5754
1.34
4.42
4.1
3.7
14.66
14.66
pmol/l
0.01
592
5295
39
190
2.10
4.40
1.6
1.8
—
—
—
0
0
23
89
2.62
4.33
1.8
1.2
—
—
—
0
0
75
459
1.69
4.21
4.8
4.2
102.90
81.86
ng/l
1.08
68
413
244
1939
1.34
3.77
3.6
3.4
422.11
363.14
mg/l
0.06
166
1284
635
5754
1.30
3.64
7.5
7.5
77.20
77.18
u/l
0.00
604
5467
254
2043
1.33
3.60
4.0
4.0
13.54
9.46
mg/mmol
0.50
168
1332
351
2955
1.29
3.56
2.5
2.2
71.39
74.23
nmol/l
1.15
312
2708
14
46
3.07
3.54
1.6
1.2
—
—
—
0
0
205
1605
1.35
3.47
2.3
2.1
3.09
2.94
mg/l
0.31
172
1390
767
7152
1.34
3.46
5.5
5.0
39.74
39.15
mmol/mol
0.93
719
6761
241
1935
1.33
3.44
2.7
2.6
369.22
5631.25
umol/l
5.90
218
1748
173
1331
1.36
3.27
1.7
1.6
416.25
27091020.00
pmol/l
1.23
150
1148
140
1041
1.40
3.25
1.7
1.6
1125.21
1173.02
nmol/l
0.22
103
791
100
703
1.47
3.14
3.4
3.1
—
—
—
0
0
122
901
1.40
2.95
8.0
6.3
1.05
1.03
mmol/l
0.20
117
849
349
3000
1.25
2.85
7.9
6.2
1.21
1.21
mmol/l
0.39
321
2767
27
137
2.00
2.82
1.1
1.1
25.48
2.19
u/ml
0.65
17
66
251
2077
1.28
2.81
3.3
3.0
19.61
86.18
e6/l
1.36
197
1578
62
404
1.57
2.79
1.3
1.4
—
—
—
0
0
27
138
1.98
2.77
1.6
2.2
139.68
132.97
g/l
0.50
19
101
266
2221
1.27
2.77
3.4
3.3
7.95
8.30
mmol/l
0.52
232
1922
33
181
1.85
2.76
1.1
1.1
10.26
2.10
u/ml
0.94
20
96
892
8590
1.47
2.76
10.3
9.4
32.02
29.59
u/l
1.12
870
8360
32
176
1.85
2.66
1.2
1.4
—
—
—
0
0
382
3338
1.24
2.65
8.7
6.8
1.21
1.21
mmol/l
0.43
331
2886
184
1475
1.31
2.62
1.5
1.5
19.86
20.00
nmol/l
0.05
160
1279
831
7923
1.34
2.61
13.4
12.1
22.11
22.78
mg/l
0.21
671
6156
274
2311
1.26
2.60
2.6
2.6
88.05
57.45
u/l
0.57
255
2176
64
428
1.53
2.59
3.1
3.5
4.75
4.70
pmol/l
0.15
55
387
430
3814
1.23
2.57
5.9
6.5
11.14
11.64
umol/l
0.48
406
3639
11
36
3.08
2.57
35.7
28.8
137.45
124.14
ug/l
0.23
11
29
471
4220
1.23
2.55
5.5
4.8
6.80
6.66
mmol/l
0.67
432
3951
137
1058
1.34
2.53
2.7
2.4
14.37
13.90
umol/l
0.20
125
985
175
1403
1.30
2.49
2.6
2.4
4.76
5.24
e6/l
0.23
160
1267
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
34
197
1.75
2.42
3.3
2.9
0.38
0.32
u/ml
0.49
18
100
354
3095
1.23
2.39
13.3
11.2
1.13
1.20
inr
1.24
112
951
266
2274
1.23
2.20
3.0
3.4
2.36
2.35
mmol/l
0.27
236
2050
6
14
4.31
2.15
1.3
1.0
—
—
—
0
0
843
8100
1.31
2.14
4.7
4.4
2.86
2.87
mmol/l
0.21
786
7623
27
152
1.80
2.14
2.4
4.2
57.74
57.87
%
0.02
27
152
366
3243
1.21
2.11
3.0
2.7
120.89
126.86
ug/l
0.22
330
3031
5
10
5.02
2.07
1.2
1.0
—
—
—
0
0
13
56
2.34
2.05
1.4
1.1
—
—
—
0
0
594
5512
1.20
2.04
3.9
3.8
10.51
10.20
mm/h
0.24
550
5145
22
118
1.88
2.03
1.3
2.5
17.25
16.91
%
0.09
15
68
22
118
1.88
2.03
1.1
1.4
0.89
0.34
nmol/l
0.46
17
100
26
150
1.75
1.92
2.2
3.8
4.25
4.25
e9/l
0.00
26
150
143
1157
1.28
1.91
2.6
3.1
2.44
2.43
mmol/l
0.08
124
1022
23
128
1.82
1.91
1.2
1.1
—
—
—
0
0
23
128
1.82
1.91
1.1
1.1
15.55
3.45
u/ml
1.19
14
54
37
239
1.57
1.81
2.0
1.8
—
—
—
0
0
478
4383
1.18
1.79
9.4
9.4
4.06
4.02
e9/l
0.13
433
3842
827
7966
1.26
1.77
4.2
4.0
1.35
1.41
mmol/l
5.00
773
7506
14
67
2.11
1.76
1.2
1.4
45683.71
51465.96
e6/l
—
7
48
15
74
2.04
1.75
1.3
1.6
76.30
61.09
%
—
10
55
783
7504
1.22
1.72
12.7
10.9
87.17
87.76
ml/min/173m2
0.31
654
6143
65
477
1.39
1.71
2.5
2.8
268.54
147.56
ng/l
0.43
57
426
16
82
1.97
1.70
1.0
1.2
—
—
—
0
0
32
203
1.60
1.70
1.3
1.1
—
—
—
0
0
134
1093
1.26
1.69
3.1
2.8
1.91
2.06
e6/l
0.13
72
574
69
514
1.37
1.66
1.3
1.3
1666.33
190.34
u/ml
1.91
62
477
16
83
1.94
1.65
2.2
1.3
—
—
—
0
0
788
7567
1.22
1.64
4.3
4.0
5.96
5.88
mmol/l
0.82
735
7027
829
8004
1.24
1.63
4.3
4.0
4.69
4.75
mmol/l
1.03
774
7565
799
7688
1.22
1.60
3.8
3.6
1.48
1.34
mmol/l
4.13
740
7212
929
9109
1.45
1.60
20.1
17.5
251.81
250.86
e9/l
0.18
911
8921
32
207
1.56
1.58
1.3
1.3
—
—
—
0
0
69
520
1.35
1.56
1.2
1.2
97.40
150.12
iu/ml
0.72
21
213
45
315
1.45
1.55
1.6
1.5
322.05
264.19
mu/l
0.68
40
290
408
3726
1.16
1.54
6.6
6.2
28.22
28.47
%
0.17
394
3536
219
1902
1.20
1.52
3.1
2.9
0.43
0.45
e6/l
0.04
168
1424
733
7010
1.19
1.50
16.4
14.5
14.41
15.11
%
0.54
723
6898
403
3683
1.16
1.50
6.4
6.0
56.58
56.78
%
0.12
390
3490
13
65
2.01
1.49
2.2
1.5
1.00
1.04
g/l
0.17
13
65
280
2491
1.17
1.47
3.7
3.0
—
—
—
0
0
9
38
2.38
1.46
2.1
1.4
—
—
—
0
0
929
9121
1.42
1.45
20.0
17.5
4.63
4.63
e12/l
0.00
910
8906
929
9125
1.41
1.40
20.1
17.6
139.28
139.57
g/l
0.24
920
9025
25
158
1.60
1.38
1.1
1.1
9.46
2.18
u/ml
1.21
17
82
58
436
1.35
1.36
4.1
3.2
5.14
5.14
kpa
0.01
53
421
55
410
1.36
1.36
4.1
3.3
0.89
1.75
mmol/l
0.69
35
302
491
4585
1.14
1.30
4.4
3.7
114.12
1484.25
e6/l
—
8
61
19
114
1.68
1.29
1.1
1.1
—
—
—
0
0
8
36
2.23
1.24
1.3
1.1
1506.88
1591.03
miu/ml
—
8
36
12
214
0.56
1.22
1.8
1.5
—
—
—
0
0
926
9107
1.35
1.22
20.3
17.6
41.37
41.78
%
0.34
873
8604
50
376
1.35
1.19
1.9
1.8
—
—
—
0
0
8
38
2.11
1.18
2.3
1.4
—
—
—
0
0
18
110
1.65
1.16
1.1
1.2
—
—
—
0
0
116
975
1.22
1.16
2.8
2.4
2.37
2.36
g/l
0.05
108
906
24
158
1.53
1.15
1.4
1.7
3411.71
15340.70
e6/l
2.33
14
119
36
259
1.40
1.13
2.7
2.0
—
—
—
0
0
16
96
1.68
1.10
1.3
1.6
—
—
—
0
0
16
96
1.68
1.10
1.3
1.6
—
—
—
0
0
123
1048
1.20
1.08
1.9
1.9
—
—
—
0
0
16
97
1.66
1.07
1.3
1.5
—
—
—
0
0
108
910
1.21
1.06
3.0
2.4
21.97
24.25
%
1.02
95
787
294
2684
1.14
1.06
3.4
3.4
35.18
33.47
u/l
0.15
282
2556
13
216
0.60
1.05
1.9
1.5
—
—
—
0
0
24
162
1.49
1.05
1.7
1.7
—
—
—
0
0
16
98
1.64
1.03
1.3
1.5
—
—
—
0
0
16
98
1.64
1.03
1.3
1.5
—
—
—
0
0
16
98
1.64
1.03
1.3
1.5
—
—
—
0
0
48
369
1.32
1.02
1.7
1.7
—
—
—
0
0
10
53
1.90
1.01
1.0
1.1
1.14
1.10
u/l
—
5
31
12
201
0.59
1.01
1.8
1.4
—
—
—
0
0
12
201
0.59
1.01
1.8
1.4
—
—
—
0
0
12
200
0.60
0.99
1.8
1.4
—
—
—
0
0
12
200
0.60
0.99
1.8
1.4
—
—
—
0
0
390
3639
1.12
0.97
3.4
3.1
0.00
0.00
estimate
-0.00
72
649
7
36
1.95
0.97
2.4
1.4
—
—
—
0
0
7
36
1.95
0.97
1.4
2.6
—
—
—
0
0
7
36
1.95
0.97
2.4
1.4
—
—
—
0
0
9
50
1.81
0.96
1.1
1.0
—
—
—
0
0
9
50
1.81
0.96
1.2
3.0
—
—
—
0
0
608
5818
1.12
0.96
3.5
3.1
46.56
47.53
u/l
0.13
578
5532
25
174
1.45
0.96
1.1
1.1
13.10
7.17
u/ml
0.53
18
98
7
37
1.90
0.94
1.4
1.4
6.32
6.38
mmol/l
—
7
37
6
27
2.23
0.93
1.3
2.4
—
—
—
0
0
180
1604
1.15
0.93
1.5
1.5
2.56
2.44
g/l
0.39
118
1037
9
52
1.74
0.92
1.1
1.2
—
—
—
0
0
9
52
1.74
0.92
1.1
1.2
—
—
—
0
0
6
28
2.15
0.91
2.5
3.2
—
921.80
—
0
5
47
367
1.29
0.91
1.3
1.4
30.14
24.69
iu/l
0.50
39
319
386
3611
1.11
0.91
3.4
3.2
0.00
0.00
estimate
0.50
81
719
201
1808
1.14
0.91
1.3
1.2
2.62
1.80
u/ml
0.24
70
505
40
306
1.32
0.90
1.4
1.4
8.93
7.29
u/l
0.48
35
261
13
79
1.65
0.88
4.5
1.9
31.69
33.37
pg
0.46
13
79
10
56
1.79
0.88
1.1
1.3
1.50
1.53
g/l
—
10
56
21
144
1.47
0.88
2.0
1.6
—
—
—
0
0
6
30
2.01
0.87
1.0
1.0
—
—
—
0
0
184
1651
1.14
0.86
1.6
1.5
—
—
—
0
0
8
44
1.82
0.86
1.0
1.1
17.97
29.77
u/l
—
8
44
188
1691
1.14
0.85
1.7
1.8
1.42
1.03
mg/l
0.62
144
1263
46
363
1.28
0.84
9.9
11.2
24.81
24.28
mmol/l
0.43
46
358
278
2566
1.12
0.83
3.6
3.9
1.50
1.94
ug/l
1.70
253
2359
148
1313
1.15
0.82
4.0
3.7
1164.70
701.17
ng/l
0.23
109
956
17
113
1.51
0.82
1.1
1.0
11.23
0.70
u/ml
—
5
40
5
97
0.51
0.78
1.0
1.4
—
0.50
nmol/l
—
0
6
5
97
0.51
0.78
1.2
1.5
—
—
—
0
0
5
98
0.51
0.78
1.0
1.4
0.52
0.62
nmol/l
—
5
92
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
12
75
1.61
0.75
1.1
1.2
41.72
51.73
u/l
0.41
12
68
27
357
0.75
0.74
1.7
1.5
—
—
—
0
0
382
3605
1.10
0.73
4.6
4.3
0.00
0.00
estimate
0.50
78
688
7
39
1.80
0.72
1.1
1.1
—
—
—
0
0
59
491
1.21
0.71
4.1
4.3
1.23
1.23
mmol/l
0.64
50
427
101
884
1.16
0.69
2.1
2.3
13.16
14.08
nmol/l
0.61
88
830
29
222
1.32
0.68
1.4
1.4
—
—
—
0
0
11
69
1.60
0.68
3.1
2.0
—
—
—
0
0
5
27
1.86
0.68
1.2
1.2
8.45
8.76
ug/l
—
5
27
23
170
1.36
0.68
1.2
1.4
—
—
—
0
0
115
1019
1.15
0.67
2.7
2.6
193.29
127.34
ug/g
0.67
97
838
5
28
1.79
0.66
5.4
2.2
—
—
—
0
0
5
28
1.79
0.66
5.4
2.2
—
—
—
0
0
5
28
1.79
0.66
5.4
2.2
—
—
—
0
0
23
172
1.35
0.64
5.0
2.3
25.10
24.64
mmol/l
0.23
23
172
130
1168
1.13
0.63
2.6
2.6
0.78
1.06
e6/l
0.53
69
650
136
1226
1.13
0.62
1.2
1.3
13.81
11.76
u/ml
0.12
55
491
10
63
1.59
0.62
1.1
1.8
—
—
—
0
0
182
1670
1.11
0.61
2.7
3.1
1438.55
942.08
ng/l
0.90
153
1381
8
50
1.60
0.61
1.8
2.2
—
—
—
0
0
74
641
1.17
0.60
4.4
3.6
1.76
1.97
mmol/l
0.16
64
538
24
183
1.32
0.60
4.3
3.8
47.36
85.17
mg/l
0.53
17
150
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
32
255
1.26
0.58
1.7
1.6
0.22
0.09
iu/ml
—
5
43
85
746
1.15
0.58
4.2
4.6
227.24
251.13
u/l
1.07
79
709
23
175
1.32
0.58
1.4
1.2
—
—
—
0
0
8
54
1.49
0.57
3.5
2.7
—
—
—
0
0
8
54
1.49
0.57
1.0
1.6
—
—
—
0
0
93
824
1.14
0.56
6.2
6.3
—
—
—
0
0
10
65
1.54
0.55
1.2
1.8
—
—
—
0
0
74
646
1.16
0.55
4.4
3.6
5.89
5.89
kpa
0.01
69
631
139
1523
0.90
0.55
2.6
2.6
0.71
0.69
ug/l
0.05
72
856
27
213
1.28
0.54
1.1
1.3
827.74
487.77
mg/l
0.51
27
201
102
1135
0.89
0.53
1.7
1.9
—
—
—
0
0
87
772
1.14
0.53
9.3
8.5
2.10
1.07
mmol/l
1.83
67
637
19
143
1.34
0.52
2.3
3.4
—
2406.83
—
0
12
82
725
1.14
0.52
1.5
1.8
—
—
—
0
0
185
1715
1.10
0.52
2.2
2.2
—
—
—
0
0
87
773
1.14
0.52
9.4
8.4
12.22
12.72
kpa
0.47
82
748
34
278
1.23
0.52
2.3
2.5
2740.88
4129.50
u/l
0.24
12
118
22
170
1.30
0.52
2.5
2.4
27.80
109.77
ug/min
1.77
14
108
83
736
1.14
0.51
1.5
1.8
—
—
—
0
0
6
41
1.47
0.50
1.5
3.7
399.33
768.59
u/ml
—
6
41
11
156
0.70
0.50
1.6
3.5
48.50
23.17
mg/l
—
6
101
29
234
1.25
0.50
1.1
1.1
—
—
—
0
0
10
67
1.50
0.49
2.3
2.6
—
—
—
0
0
29
235
1.24
0.48
1.1
1.1
—
—
—
0
0
56
485
1.16
0.48
1.4
1.6
—
—
—
0
0
114
1251
0.90
0.48
1.9
2.0
—
—
—
0
0
29
236
1.24
0.47
1.7
2.2
406.58
313.86
ug/l
0.18
29
226
141
1300
1.10
0.46
1.2
1.3
20.93
31.26
iu/ml
0.79
43
410
5
81
0.62
0.46
1.0
1.1
—
—
—
0
0
24
192
1.26
0.45
8.8
5.5
470.29
351.29
iu/ml
—
7
24
23
183
1.26
0.45
4.4
3.8
32.02
31.95
mg/l
0.00
17
151
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
50
1.40
0.45
1.1
1.1
—
—
—
0
0
200
1876
1.08
0.44
3.9
3.5
0.00
0.01
estimate
1.08
73
668
29
239
1.22
0.43
1.8
2.2
—
—
—
0
0
8
57
1.41
0.42
1.4
2.4
0.19
0.22
e9/l
—
8
48
50
572
0.87
0.41
1.9
2.0
—
—
—
0
0
8
58
1.38
0.41
1.4
2.3
516.50
633.37
e6/l
—
8
48
11
79
1.40
0.41
3.1
1.9
—
—
—
0
0
19
238
0.79
0.40
1.6
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
339.67
—
0
12
35
297
1.19
0.40
1.5
1.3
321.39
232.26
miu/ml
0.48
13
143
7
101
0.69
0.39
1.4
3.1
106.57
18.64
u/ml
—
7
101
77
694
1.12
0.39
2.4
2.1
354.18
365.95
nmol/l
0.19
68
653
22
178
1.24
0.39
1.5
1.5
82.50
105.70
u/ml
—
6
32
17
133
1.28
0.38
1.8
2.0
12.88
13.05
%
0.42
17
133
5
36
1.39
0.38
1.2
1.2
71.60
12.18
u/l
—
5
28
13
98
1.33
0.37
1.1
1.1
—
—
—
0
0
9
70
1.29
0.36
1.0
1.0
—
—
—
0
0
598
5850
1.06
0.36
3.2
3.2
—
—
—
0
0
23
276
0.83
0.34
1.7
1.8
—
—
—
0
0
96
1039
0.92
0.33
1.6
1.4
—
—
—
0
0
6
46
1.31
0.33
1.2
1.1
—
—
—
0
0
13
101
1.29
0.32
1.1
1.1
—
—
—
0
0
276
2653
1.06
0.31
3.2
3.2
60.52
39.90
ng/l
0.31
168
1663
18
148
1.22
0.29
1.8
1.6
—
—
—
0
0
7
57
1.23
0.29
1.0
1.0
—
—
—
0
0
15
121
1.24
0.28
2.5
1.9
—
—
—
0
0
17
140
1.22
0.27
1.0
1.2
—
7.45
—
0
12
8
64
1.25
0.27
19.9
11.6
0.63
0.62
mmol/l
—
8
59
8
65
1.23
0.27
1.4
2.0
—
—
—
0
0
31
352
0.88
0.26
3.6
2.5
1.13
1.37
%
1.08
31
352
25
216
1.16
0.25
2.2
3.3
—
—
—
0
0
39
434
0.89
0.25
1.0
1.1
—
—
—
0
0
29
255
1.14
0.24
1.1
1.1
4.67
6.25
u/ml
—
7
38
16
133
1.21
0.24
1.7
1.5
—
—
—
0
0
23
199
1.16
0.23
1.0
1.2
—
2.79
—
0
7
5
38
1.32
0.23
1.2
1.2
174.20
73.65
u/l
—
5
31
5
39
1.28
0.23
5.4
1.9
—
—
—
0
0
5
39
1.28
0.23
5.4
1.9
—
—
—
0
0
211
2035
1.05
0.22
1.8
1.6
1.50
1.48
mmol/l
0.08
177
1763
10
79
1.27
0.22
1.0
1.0
297.40
285.51
mg/l
—
10
71
20
172
1.17
0.22
2.3
1.8
—
—
—
0
0
5
41
1.22
0.22
1.2
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
0.40
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
44
402
1.10
0.21
2.4
1.8
33.93
36.76
nmol/l
0.40
44
391
11
89
1.24
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
292
2842
1.04
0.20
3.6
3.2
—
—
—
0
0
79
840
0.94
0.20
4.3
4.1
29.19
30.63
%
0.53
58
599
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
216
2090
1.04
0.20
2.3
2.1
232.13
211.44
u/l
0.17
208
1996
41
447
0.91
0.19
1.8
1.9
—
—
—
0
0
31
343
0.90
0.19
3.6
2.5
0.58
0.66
%
0.59
31
343
13
109
1.20
0.18
1.2
1.4
145.91
183.22
pmol/l
0.62
13
109
7
58
1.21
0.18
1.0
1.2
—
81.83
—
0
6
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
5
66
0.76
0.17
5.4
1.7
—
—
—
0
0
5
66
0.76
0.17
5.4
1.7
—
—
—
0
0
5
66
0.76
0.17
5.4
1.7
—
—
—
0
0
5
67
0.75
0.17
1.0
1.2
—
—
—
0
0
5
67
0.75
0.17
1.0
2.0
—
—
—
0
0
5
68
0.73
0.17
1.0
1.2
—
—
—
0
0
14
161
0.87
0.15
1.2
1.2
—
—
—
0
0
7
87
0.80
0.14
1.1
1.7
—
—
—
0
0
7
87
0.80
0.14
1.1
1.7
—
—
—
0
0
10
84
1.19
0.14
8.9
14.1
822.00
775.29
nmol/l
—
10
79
10
84
1.19
0.14
1.1
1.9
—
—
—
0
0
14
122
1.15
0.13
1.2
1.7
—
—
—
0
0
39
364
1.07
0.13
1.7
1.8
5.67
3.93
mg/l
0.66
29
259
15
132
1.14
0.13
1.2
1.1
—
10.15
—
0
14
19
211
0.90
0.13
1.5
1.5
325.52
296.95
ug/g
—
9
122
13
113
1.15
0.13
1.5
2.2
—
1340.00
—
0
8
98
1018
0.96
0.13
2.0
1.7
—
—
—
0
0
13
114
1.14
0.12
1.1
1.3
—
—
—
0
0
339
3436
0.98
0.10
2.6
2.5
—
—
—
0
0
76
733
1.04
0.09
2.4
2.7
40.80
104.48
u/l
0.49
65
644
15
135
1.11
0.09
1.3
1.4
—
—
—
0
0
15
135
1.11
0.09
1.3
1.4
—
—
—
0
0
54
563
0.96
0.09
2.0
2.3
7.39
8.44
ug/l
0.21
46
512
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
12
134
0.89
0.08
1.3
1.2
1.60
5.38
u/ml
—
5
61
20
185
1.08
0.08
2.0
1.9
3.38
5.38
iu/l
—
5
66
42
439
0.95
0.07
1.1
1.3
—
—
—
0
0
7
80
0.87
0.07
1.6
1.5
—
—
—
0
0
9
102
0.88
0.06
1.2
1.1
—
—
—
0
0
16
172
0.93
0.06
1.5
1.5
—
—
—
0
0
19
178
1.07
0.05
2.3
1.8
—
—
—
0
0
63
614
1.03
0.05
4.0
4.7
6.94
29.68
ug/l
0.96
53
500
15
142
1.06
0.02
1.3
1.8
—
—
—
0
0
136
1348
1.01
0.02
1.7
1.9
1.28
1.46
%
3.59
125
1211
11
103
1.07
0.02
1.3
1.6
—
—
—
0
0
204
2051
0.99
0.01
3.4
3.5
24.40
20.79
%
1.74
70
787
12
127
0.94
0.01
1.2
1.5
—
—
—
0
0
11
104
1.06
0.01
1.3
1.7
—
—
—
0
0
160
1593
1.01
0.00
3.9
3.4
1.02
1.02
kg/l
1.26
20
204
20
206
0.97
0.00
1.3
1.2
—
—
—
0
0
13
126
1.03
0.00
1.0
1.1
—
—
—
0
0
14
138
1.01
0.00
1.1
1.2
1.80
4.00
u/ml
—
5
44
14
138
1.01
0.00
1.1
1.1
—
—
—
0
0
24
238
1.01
0.00
2.1
1.8
—
—
—
0
0
59
588
1.00
0.00
2.9
2.4
70.93
74.07
ml/min/173m2
0.24
28
236
33
331
1.00
0.00
1.4
1.4
—
—
—
0
0
18
181
0.99
0.00
1.9
1.6
—
—
—
0
0
12
125
0.96
0.00
2.9
1.8
—
—
—
0
0
12
125
0.96
0.00
2.9
1.8
—
—
—
0
0
5
53
0.94
0.00
1.2
8.1
—
65.50
—
0
20
5
50
1.00
0.00
3.2
2.8
44760.00
40012.10
ug/l
—
5
50
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
9
90
1.00
0.00
1.9
2.3
—
—
—
0
0
8
85
0.94
0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
69
1.01
-0.00
1.3
2.0
765.43
608.17
e6/l
—
7
69
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
1.36
—
0
5
9
92
0.98
-0.00
1.3
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
7
79
0.89
-0.00
1.6
1.3
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.4
83.40
75.68
umol/l
—
5
59
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.3
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
57.33
—
0
6
6
62
0.97
-0.00
3.3
4.0
—
—
—
0
0
20
200
1.00
-0.00
1.5
1.2
290.79
237.45
u/ml
0.35
14
123
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
12.79
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CORNEALDEFORM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALDEFORM | 1.128 [0.92, 1.38] | 0.242 |
| Birth year | 0.996 [0.99, 1.0] | 0.321 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 1933 females with H7_CORNEALDEFORM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALDEFORM | 1.021 [0.86, 1.21] | 0.808 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 189 out of 4002 males with H7_CORNEALDEFORM died.
Mortality risk
Mortality risk for people of age
years, who have H7_CORNEALDEFORM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.109% | 0.207% |
| 5 | 0.733% | 1.187% |
| 10 | 1.729% | 2.947% |
| 15 | 3.295% | 5.608% |
| 20 | 5.82% | 9.48% |
Relationships between endpoints
↥Index endpoint: H7_CORNEALDEFORM – Keratoconus
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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