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Toxic effect of alcohol

EFO MESH Endpoint Browser PheWeb

ST19_TOXIC_EFFECT_ALCOHOL

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — T51
  • Hospital discharge: ICD-9 — 980
  • Hospital discharge: ICD-8 — 980
  • Hospital discharge: excluded ICD-10 — T51.0
  • Hospital discharge: excluded ICD-9 — 9800
  • Cause of death: ICD-10 — T51
  • Cause of death: ICD-9 — 980
  • Cause of death: ICD-8 — 980
  • Cause of death: excluded ICD-10 — T51.0
  • Cause of death: excluded ICD-9 — 9800

2 out of 7 registries used, show all original rules.

829

4. Check minimum number of events

None

829

5. Include endpoints

None

829

6. Filter based on genotype QC (FinnGen only)

804

Control definitions (FinnGen only)

Control exclude
ST19_TOXIC_EFFEC_SUBST_CHIEF_NONME_SOURCE

Extra metadata

Level in the ICD hierarchy
3
Special
ALCOTOXIC
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T51-T65
Name in latin
Effectus alcoholicus toxicus

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10946 3014 7772
Only index persons 7769 2497 5272
Unadjusted period prevalence (%)
Whole population 0.18 0.09 0.22
Only index persons 0.17 0.09 0.20
Median age at first event (years)
Whole population 28.20 21.94 30.22
Only index persons 22.55 19.17 24.15

-FinnGen-

Key figures

All Female Male
Number of individuals 804 298 506
Unadjusted period prevalence (%) 0.19 0.11 0.23
Median age at first event (years) 25.57 20.60 28.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
829
Matched controls
8290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
98000
ICD-8 Finland
Toxic effect of alcohol, Ethyl alcohol
+∞
307.7
427
*
T51.9
ICD-10 Finland
Toxic effect: Alcohol, unspecified
+∞
167.5
155
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
16.1
158.3
144
107
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.5
150.6
232
362
T36
ICD-10 Finland
Poisoning by systemic antibiotics
11.7
134.0
149
152
E8699
ICD-8 Finland
Accidental poisoning by other and unspecified solid and liquid substances
254.1
128.8
129
6
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
65.1
119.2
66
11
X45
ICD-10 Finland
Accidental poisoning by and exposure to alcohol
186.5
110.3
113
7
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
21.8
109.3
83
42
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
49.0
94.0
55
12
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
13.2
87.9
87
73
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
25.9
82.4
58
24
30310
ICD-8 Finland
Alcoholism, Habitual excessive drinking
44.2
76.8
46
11
F10.09
ICD-10 Finland
Alcohol intoxication UNS
11.5
74.5
80
76
T51.0
ICD-10 Finland
Toxic effect: Ethanol
+∞
74.1
70
*
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
18.8
72.0
58
33
T51.8
ICD-10 Finland
Toxic effect: Other alcohols
+∞
65.5
62
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
7.9
64.3
93
130
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
17.6
63.9
53
32
F10.20
ICD-10 Finland
Alcohol dependence currently independent
10.2
63.4
74
79
98099
ICD-8 Finland
Toxic effect of alcohol, Other
+∞
63.3
60
*
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
11.9
61.3
64
58
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
15.9
58.4
51
34
T51.1
ICD-10 Finland
Toxic effect: Methanol
+∞
58.0
55
*
N07BB01
ATC
disulfiram; oral
5.9
56.1
109
207
F10.25
ICD-10 Finland
Alcohol dependence continuous use
9.1
51.3
65
77
N05AA02
ATC
levomepromazine; systemic
6.1
49.6
91
163
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
13.3
44.6
43
34
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
10.6
42.8
48
48
F10.24
ICD-10 Finland
Alcohol depence active use
8.6
42.8
56
69
V03AA01, ,
ATC
9.7
39.5
47
51
P16
ICPC
Acute alcohol abuse
8.1
38.6
53
69
N05BA01
ATC
diazepam; systemic, rectal
3.4
38.3
166
576
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
11.0
36.9
40
38
N05BA02
ATC
chlordiazepoxide; systemic
6.6
36.9
61
98
P15
ICPC
Chronic alcohol abuse
5.4
36.7
76
152
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
9.4
36.3
44
49
E9809
ICD-8 Finland
Poisoning by solid or liquid substances, undetermined whether accidentally or purposely inflicted, Other and unspecified solid and liquid substances
187.9
35.0
36
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
35.0
166
606
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
9.5
33.2
40
44
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.4
31.4
38
42
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.7
31.2
108
322
N05BA04
ATC
oxazepam; oral
2.4
29.0
258
1291
N05CD07
ATC
temazepam; oral
3.1
28.6
133
477
N05AH04
ATC
quetiapine; oral
2.6
28.5
208
947
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
10.7
28.2
31
30
N05AB01
ATC
dixyrazine; systemic
9.3
27.9
34
38
30041
ICD-8 Finland
Neuroses, Depressiva
10.3
27.5
31
31
K92.0
ICD-10 Finland
Haematemesis
6.1
26.4
47
81
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.1
26.4
76
198
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
8.1
25.7
35
45
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.7
24.8
35
47
N06AX11
ATC
mirtazapine; oral
2.2
24.7
326
1902
N05AF03
ATC
chlorprothixene; systemic
5.4
24.1
49
96
T51.2
ICD-10 Finland
Toxic effect: 2-Propanol
+∞
24.1
23
*
N06AB04
ATC
citalopram; systemic
2.4
23.5
200
969
N03AG01
ATC
valproic acid; systemic, rectal
3.6
23.2
82
247
N05CF01
ATC
zopiclone; oral
2.2
23.1
297
1707
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
22.5
169
772
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.9
20.9
29
38
N06AB03
ATC
fluoxetine; oral
2.7
20.8
130
542
30180
ICD-8 Finland
Personality disorders, Immatura
30.9
20.7
27
9
WX730
NOMESCO Finland
Conventional respirator
8.2
20.1
27
34
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
19.9
172
833
N05AD01
ATC
haloperidol; systemic
4.8
19.6
45
98
85000
ICD-8 Finland
Concussion, Current or unspecified
5.1
19.4
41
83
30399
ICD-8 Finland
Other and unspecified alcoholism
47.2
19.3
23
5
S06.0
ICD-10 Finland
Concussion
2.7
19.3
119
493
Z72.1
ICD-10 Finland
Alcohol use
6.2
18.7
32
53
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.9
18.3
92
342
9809X
ICD-9 Finland
Toxic effect of alcohol, Unspecified alcohol
+∞
17.8
17
*
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.7
17.7
42
94
Y91.1
ICD-10 Finland
Moderate alcohol intoxication
183.8
17.6
18
*
E8599
ICD-8 Finland
Accidental poisoning by other and unspecified drugs and medicaments, Drugs, unspecified
51.1
17.0
20
*
N05AH03
ATC
olanzapine; systemic
3.0
16.8
80
288
N05BE01
ATC
buspirone; oral
4.1
16.8
47
120
Y19
ICD-10 Finland
Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent
28.2
16.6
22
8
F61.0
ICD-10 Finland
Mixed personality disorders
5.8
16.4
30
53
N06AX03
ATC
mianserin; oral
3.6
16.3
55
160
N05AH02
ATC
clozapine; systemic
4.8
16.2
37
80
R40.2
ICD-10 Finland
Coma, unspecified
12.0
16.1
29
25
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
3.7
15.4
49
137
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.6
15.3
29
53
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.8
15.1
77
288
Z2446
NOMESCO Finland
Social worker
2.9
14.7
73
269
T65.9
ICD-10 Finland
Toxic effect: Toxic effect of unspecified substance
152.6
14.5
15
*
E970A
ICD-9 Finland
Injury due to legal intervention by firearms
27.7
14.3
19
7
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
14.2
259
1629
N05AB03
ATC
perphenazine; systemic, rectal
3.6
14.1
47
136
E9599
ICD-8 Finland
Late effect of self-inflicted injury
30.6
13.9
18
6
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
13.7
140
720
F10.07
ICD-10 Finland
Pathological alcohol intoxication
76.4
13.6
15
*
E850A
ICD-9 Finland
Accidental poisoning by analgesics, antipyretics, antirheumatics
76.4
13.6
15
*
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
5.3
13.5
27
52
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.1
13.5
37
93
AA1AD
NOMESCO Finland
CT of head and brain
1.8
13.4
239
1490
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.4
13.2
100
454
A06AD11
ATC
lactulose; oral
2.2
13.1
126
631
9800A
ICD-9 Finland
Toxic effect of alcohol, Ethyl alcohol
28.9
13.0
17
6
N06AA12
ATC
doxepin; systemic
3.0
12.7
57
198
N06AB06
ATC
sertraline; oral
2.2
12.7
110
528
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
12.5
221
1369
SPAT1265
SPAT
Breathalyser
5.9
12.3
22
38
Y91.2
ICD-10 Finland
Severe alcohol intoxication
38.2
12.2
15
*
N04AA02
ATC
biperiden; systemic
4.6
12.2
29
65
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
8.9
12.1
25
29
N05CD02
ATC
nitrazepam; oral
5.3
12.1
24
46
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
19.2
11.6
17
9
Y91.0
ICD-10 Finland
Mild alcohol intoxication
+∞
11.5
11
*
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
121.6
11.5
12
*
97010
ICD-8 Finland
Adverse effect of psychotherapeutics, Tranquillisers
35.6
11.3
14
*
N06AB10
ATC
escitalopram; oral
1.9
11.2
181
1086
N06AB05
ATC
paroxetine; oral
2.7
11.1
59
225
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.3
11.1
42
132
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.0
11.0
50
175
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
11.0
174
1036
N02AX02
ATC
tramadol; systemic, rectal
1.7
11.0
355
2585
P29
ICPC
Psychological sympt/compl other
2.4
10.9
76
332
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.9
10.8
53
194
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.5
10.8
26
59
96798
ICD-8 Finland
Other sleeping pills and sedatives
28.4
10.7
14
5
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.5
10.7
36
105
N05BA12
ATC
alprazolam; oral
2.2
10.6
89
421
30188
ICD-8 Finland
Personality disorders, Alia definita
11.4
10.6
19
17
29120
ICD-8 Finland
Alcoholic psychosis, Other alcoholic hallucinosis
111.4
10.4
11
*
30199
ICD-8 Finland
Personality disorders, Unspecified
111.4
10.4
11
*
98020
ICD-8 Finland
Toxic effect of alcohol, Isopropyl alcohol
+∞
10.4
10
*
N05AD03
ATC
melperone; systemic
7.9
10.4
23
30
5353A
ICD-9 Finland
Gastritis and duodenitis, Alcoholic gastritis
33.0
10.3
13
*
WX892
NOMESCO Finland
Monitored bed care
2.4
10.3
72
314
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
10.8
10.3
19
18
2918A
ICD-9 Finland
Alcoholic psychoses, Other specified alcoholic psychosis
23.7
10.3
14
6
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.0
10.1
45
156
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
10.1
63
261
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
8.6
10.1
21
25
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.9
10.1
22
46
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
12.4
9.9
17
14
N06AX16
ATC
venlafaxine; oral
2.0
9.9
123
676
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
8.9
9.8
20
23
N05AX08
ATC
risperidone; systemic
2.3
9.8
80
374
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.1
9.8
92
456
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
9.8
83
395
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
8.0
9.7
21
27
W19
ICD-10 Finland
Unspecified fall
2.2
9.6
87
424
C07AA05
ATC
propranolol; systemic
1.8
9.6
165
1005
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
11.5
9.6
17
15
E9609
ICD-8 Finland
Fight, brawl, rape
11.5
9.6
17
15
P99
ICPC
Psychological disorders other
3.2
9.6
37
118
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
9.2
9.6
19
21
N05AC02
ATC
thioridazine; oral
4.2
9.5
25
61
N07BA03
ATC
varenicline; oral
2.6
9.5
54
214
N05AX12
ATC
aripiprazole; systemic
2.8
9.3
46
169
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
9.7
9.3
18
19
TK800
NOMESCO Finland
Hemodialysis
3.8
9.2
28
76
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
13.9
9.2
15
11
C03CA01
ATC
furosemide; systemic
1.7
9.2
207
1361
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
7.9
9.2
20
26
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
9.1
51
200
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
4.5
9.1
22
50
N05AA01
ATC
chlorpromazine; systemic, rectal
4.7
9.1
21
46
K70.1
ICD-10 Finland
Alcoholic hepatitis
10.2
9.0
17
17
N03AX09
ATC
lamotrigine; oral
2.7
9.0
49
190
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
4.7
8.9
20
43
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.7
8.9
20
43
N03AF01
ATC
carbamazepine; oral, rectal
2.6
8.8
49
192
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.8
8.8
44
163
N05AN01
ATC
lithium; oral
3.5
8.7
29
84
F60.2
ICD-10 Finland
Dissocial personality disorder
14.2
8.7
14
10
97920
ICD-8 Finland
Alcohol in combination with specified medicinal agents, With nonbarbiturate sedatives
50.5
8.7
10
*
29100
ICD-8 Finland
Alcoholic psychosis, Delirium tremens
50.5
8.7
10
*
92000
ICD-8 Finland
Contusion of face, scalp and neck except eye(s), Current injury
10.2
8.5
16
16
97940
ICD-8 Finland
Alcohol in combination with specified medicinal agents, With psychopharmacological agents
27.8
8.5
11
*
F10.02
ICD-10 Finland
Alcohol-related acute intoxication with other acute clinical complications
20.3
8.5
12
6
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
8.5
79
390
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
8.5
113
635
98098
ICD-8 Finland
Toxic effect of alcohol, Other alcohols
+∞
8.3
8
*
E87.2
ICD-10 Finland
Acidosis
9.6
8.3
16
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.3
366
2815
S01.0
ICD-10 Finland
Open wound of scalp
2.2
8.2
71
340
K29.2
ICD-10 Finland
Alcoholic gastritis
14.6
8.2
13
9
X84
ICD-10 Finland
Intentional self-harm by unspecified means
14.6
8.2
13
9
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
8.2
101
552
A98
ICPC
Health maint/preventive medicine
0.6
8.1
687
7423
T74.1
ICD-10 Finland
Physical abuse
3.8
8.1
24
64
SPAT1247
SPAT
Outpatient detoxication and monitoring
11.8
8.1
14
12
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.8
8.1
39
142
R51.80
ICD-10 Finland
Headache
1.8
8.0
128
760
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.3
8.0
30
94
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.7
7.9
25
70
F10.05
ICD-10 Finland
Alcohol-related acute intoxication with coma
13.2
7.9
13
10
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
8.6
7.8
16
19
R41.0
ICD-10 Finland
Disorientation, unspecified
3.3
7.7
28
86
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
7.7
73
363
30088
ICD-8 Finland
Neuroses, Other
12.0
7.6
13
11
Z91.5
ICD-10 Finland
Personal history of self-harm
25.3
7.6
10
*
P18
ICPC
Medication abuse
7.2
7.5
17
24
P19
ICPC
Drug abuse
7.7
7.4
16
21
N02BF02
ATC
pregabalin; oral
2.3
7.4
57
261
P01
ICPC
Feeling anxious/nervous/tense
1.9
7.4
101
572
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
8.5
7.3
15
18
X65
ICD-10 Finland
Intentional self-poisoning by and exposure to alcohol
+∞
7.3
7
*
T51
ICD-10 Finland
Toxic effect of alcohol
+∞
7.3
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
7.3
271
1994
30799
ICD-8 Finland
Transient situational disturbances
15.9
7.2
11
7
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
15.9
7.2
11
7
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
4.5
7.2
17
38
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.0
7.2
20
51
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.9
7.2
33
117
30430
ICD-8 Finland
Drug dependence, Other hypnotics and sedatives or tranquillisers
30.3
7.2
9
*
F10.4
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state with delirium
20.2
7.1
10
5
Y90.8
ICD-10 Finland
Blood alcohol level of 240 mg/100 ml or more
20.2
7.1
10
5
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.8
7.0
34
124
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.0
7.0
30
102
V03AB30, ,
ATC
6.4
7.0
17
27
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.6
7.0
38
148
Z72.2
ICD-10 Finland
Drug use
13.9
6.9
11
8
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
9.4
6.8
13
14
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
6.8
79
424
SPAT1227
SPAT
Substance abuse rehabilitation
7.3
6.7
15
21
N05CF02
ATC
zolpidem; oral
1.7
6.7
132
832
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.2
6.6
26
84
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.2
6.6
25
79
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
3.5
6.6
22
64
Z72.8
ICD-10 Finland
Other problems related to lifestyle
12.4
6.6
11
9
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.0
6.6
28
95
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
8.8
6.6
13
15
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
3.9
6.6
19
50
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
6.5
48
215
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.4
6.5
23
70
X78
ICD-10 Finland
Intentional self-harm by sharp object
7.5
6.4
14
19
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.4
167
1129
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
3.8
6.4
19
51
N02AA05
ATC
oxycodone; systemic
1.7
6.4
129
819
Y07
ICD-10 Finland
Other maltreatment
6.6
6.4
15
23
AA400
NOMESCO Finland
Electroconvulsive therapy
6.6
6.4
15
23
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.2
6.3
13
16
N03AE01
ATC
clonazepam; systemic
2.3
6.3
49
225
P74
ICPC
Anxiety disorder/anxiety state
2.4
6.3
43
187
98090, ,
ICD-8 Finland
+∞
6.3
6
*
9802A
ICD-9 Finland
Toxic effect of alcohol, Isopropyl alcohol
+∞
6.3
6
*
T52.3
ICD-10 Finland
Toxic effect: Glycols
+∞
6.3
6
*
30488
ICD-8 Finland
Drug dependence, Other
+∞
6.3
6
*
30398
ICD-8 Finland
Alcoholism, Alius definitus
+∞
6.3
6
*
9808X
ICD-9 Finland
Toxic effect of alcohol, Other specified alcohols
+∞
6.3
6
*
A46
ICD-10 Finland
Erysipelas
1.7
6.2
119
743
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
12.6
6.1
10
8
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
3.6
6.1
19
53
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
6.0
60
304
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
10.1
6.0
11
11
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.9
6.0
79
441
N05BA06
ATC
lorazepam; systemic, sublingual
2.3
6.0
46
210
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
6.0
181
1264
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
6.1
6.0
15
25
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.6
6.0
16
29
Z72.0
ICD-10 Finland
Tobacco use
2.8
6.0
29
106

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
64
10.39
54.25
3.9
1.5
1.92
1.07
promille
2.70
50
53
164
697
2.69
25.61
6.8
3.8
7.36
7.38
ph
2.45
99
401
156
668
2.64
23.88
7.0
3.8
1.54
1.80
mmol/l
0.31
135
571
59
138
4.53
23.57
5.8
2.4
—
—
—
0
0
75
227
3.53
21.00
8.7
2.6
—
—
—
0
0
26
34
7.86
18.77
3.9
1.7
—
—
—
0
0
78
260
3.21
18.72
5.1
1.8
—
—
—
0
0
84
305
2.95
17.39
4.7
2.0
—
—
—
0
0
162
808
2.25
17.34
10.1
9.8
0.75
0.88
mmol/l
0.13
135
671
163
816
2.24
17.28
10.4
9.8
7.40
7.41
ph
1.05
95
456
137
663
2.28
15.66
11.6
8.9
1.63
1.34
mmol/l
1.54
137
653
85
332
2.74
15.35
4.7
1.9
—
—
—
0
0
130
621
2.30
15.31
14.8
10.4
—
—
—
0
0
85
338
2.69
14.82
4.7
1.9
—
—
—
0
0
138
695
2.18
14.24
11.6
10.6
122.79
122.92
g/l
0.02
138
681
83
337
2.63
13.87
4.7
1.9
—
—
—
0
0
293
1951
1.78
13.14
5.2
4.5
—
—
—
0
0
80
335
2.54
12.54
4.9
1.8
—
—
—
0
0
25
29
8.85
12.07
10.8
1.7
93.09
80.88
umol/l
0.16
11
17
40
117
3.54
11.79
5.2
6.0
420.64
351.17
umol/l
1.57
33
106
66
263
2.64
11.44
1.9
2.3
518.85
500.76
ug/l
0.03
66
251
92
428
2.29
11.43
8.7
8.0
23.90
24.56
mmol/l
0.70
92
407
317
2249
1.66
10.81
4.4
2.7
56.62
63.02
u/l
1.03
304
2120
339
2484
1.62
9.95
4.7
3.5
37.56
34.45
u/l
0.60
324
2362
253
1731
1.66
9.72
3.8
2.8
—
—
—
0
0
465
3696
1.59
9.54
8.3
7.1
11.22
11.69
umol/l
0.45
448
3543
621
6913
0.59
8.96
5.3
4.9
1.37
1.40
mmol/l
0.76
584
6525
626
6939
0.60
8.52
5.5
5.0
4.49
4.62
mmol/l
2.55
591
6589
81
408
2.09
8.25
2.3
1.7
0.36
0.32
mg/l
0.20
54
213
297
2185
1.56
8.18
3.1
2.2
363.72
277.01
u/l
0.46
290
2089
639
7014
0.61
7.61
6.1
5.6
2.64
2.73
mmol/l
1.90
601
6633
591
6600
0.64
7.55
4.6
4.2
1.43
1.35
mmol/l
1.56
554
6186
375
2980
1.47
6.82
12.5
7.1
1.19
1.21
mmol/l
3.86
361
2782
178
1207
1.60
6.79
4.4
3.9
0.77
0.82
mmol/l
5.38
171
1149
296
2252
1.49
6.66
3.9
3.3
76.56
86.79
e6/l
0.09
225
1719
238
3138
0.66
6.61
3.2
3.0
—
—
—
0
0
110
661
1.77
6.61
5.2
2.6
77.76
113.97
u/l
0.17
93
559
48
215
2.31
6.55
7.0
4.3
1.48
1.31
mmol/l
0.41
48
209
95
561
1.78
6.05
3.1
2.3
4.86
8.95
ug/l
3.54
88
513
364
2937
1.43
5.81
4.6
3.2
6.25
6.15
ph
0.89
205
1735
263
2000
1.46
5.77
6.8
4.3
7.40
7.40
ph
0.15
188
1432
322
2554
1.43
5.60
4.8
3.9
33.42
75.55
e6/l
1.68
233
1823
244
1839
1.46
5.58
3.8
3.1
—
0.00
estimate
—
0
10
209
1536
1.48
5.41
2.9
2.6
5.34
5.06
e6/l
0.10
193
1399
219
1630
1.47
5.31
5.5
3.5
1.02
1.02
kg/l
1.47
147
1088
482
4125
1.40
5.31
9.2
5.5
7.02
6.71
mmol/l
2.07
468
3916
719
7588
0.60
5.30
36.4
23.2
136.42
138.49
g/l
3.04
714
7523
719
7586
0.61
5.24
36.3
23.2
7.42
6.75
e9/l
6.17
701
7447
719
7585
0.61
5.21
37.5
23.6
40.88
41.18
%
1.01
714
7515
719
7585
0.61
5.21
36.2
23.1
4.52
4.59
e12/l
2.95
700
7450
719
7585
0.61
5.21
36.0
23.0
30.39
30.41
pg
0.10
714
7520
185
1339
1.49
5.14
5.7
3.9
172.44
467.79
ng/l
1.72
146
1028
719
7582
0.61
5.12
36.1
23.0
91.06
90.93
fl
0.34
714
7518
719
7581
0.61
5.10
36.3
23.1
253.65
247.44
e9/l
1.59
705
7460
284
2232
1.41
5.09
2.8
2.4
—
—
—
0
0
139
1963
0.65
5.09
2.6
2.9
0.64
0.73
ug/l
1.02
97
1147
5
241
0.20
5.07
1.2
1.5
—
—
—
0
0
397
3319
1.38
4.87
10.9
7.9
1.19
1.21
mmol/l
3.69
362
2892
382
3178
1.37
4.81
11.6
13.1
1.17
1.22
inr
1.29
320
2635
250
1939
1.41
4.78
3.9
3.2
0.54
0.43
e6/l
0.24
183
1410
497
4316
1.38
4.77
5.6
4.2
265.78
839.58
e6/l
—
9
67
264
2074
1.40
4.67
8.3
6.4
—
—
—
0
0
53
289
1.89
4.39
6.4
6.9
0.75
0.88
%
1.71
53
272
146
1038
1.49
4.39
2.6
2.1
—
—
—
0
0
617
6653
0.72
4.08
5.5
4.9
6.23
5.96
mmol/l
3.79
576
6190
121
842
1.51
4.03
2.1
1.7
—
—
—
0
0
7
7
10.07
4.01
2.9
1.1
—
—
—
0
0
585
5300
1.35
3.79
10.5
8.6
81.80
78.42
u/l
0.67
569
5067
55
320
1.77
3.74
6.4
6.4
2.08
1.60
%
1.36
55
303
25
109
2.33
3.72
4.1
1.3
66.06
64.27
mmol/l
0.06
18
96
172
1303
1.40
3.67
3.2
2.9
503.94
549.52
mosm/kgh2o
1.90
153
1146
456
3996
1.31
3.67
14.3
10.3
4.46
4.11
e9/l
2.51
401
3505
421
3658
1.31
3.56
4.3
3.5
0.00
0.00
estimate
0.50
78
773
40
214
1.91
3.55
7.2
8.3
1.71
1.23
mmol/l
1.26
40
187
223
1772
1.35
3.54
7.8
4.2
89.57
90.05
%
0.11
218
1747
424
3696
1.30
3.47
4.4
3.5
0.00
2.08
estimate
0.50
79
780
71
455
1.61
3.40
6.0
4.6
128.61
85.43
ng/l
1.00
62
403
426
3722
1.30
3.40
4.4
3.6
0.00
0.44
estimate
0.53
67
719
6
7
8.62
3.26
3.5
1.1
—
—
—
0
0
30
150
2.04
3.24
8.2
10.1
103.97
105.34
mmol/l
0.72
30
137
30
150
2.04
3.24
8.2
10.1
12.97
11.47
mmol/l
0.83
30
137
42
236
1.82
3.23
2.0
2.2
28046.51
3910.46
u/l
—
8
95
157
1197
1.38
3.21
3.7
2.9
0.96
0.94
e6/l
0.04
88
638
613
6559
0.75
3.21
7.7
6.1
40.41
39.29
mmol/mol
1.90
581
6237
172
1332
1.37
3.19
1.6
1.7
427.81
33655107.13
pmol/l
1.42
148
1141
270
3199
0.77
3.12
4.0
4.8
2.19
2.10
ug/l
0.10
244
2935
34
181
1.92
3.09
3.6
3.3
3.41
1.93
index
0.57
17
105
32
167
1.95
3.08
3.4
3.4
—
—
—
0
0
343
2941
1.28
3.07
7.0
5.5
35.04
36.11
g/l
2.43
322
2793
137
1034
1.39
2.97
3.4
2.7
2.34
2.32
g/l
0.11
127
967
123
913
1.41
2.94
2.0
1.7
—
—
—
0
0
43
685
0.61
2.64
1.3
1.7
3.31
3.49
mmol/l
0.53
31
508
179
1437
1.31
2.59
2.3
1.9
—
—
—
0
0
371
3260
1.25
2.58
3.3
2.8
—
—
estimate
—
0
0
9
25
3.63
2.58
4.1
2.8
0.63
0.60
mmol/l
—
9
25
240
2005
1.28
2.56
4.4
3.6
0.00
0.01
estimate
1.34
72
716
12
44
2.75
2.55
2.2
3.0
6.80
7.98
mmol/l
0.83
12
44
125
954
1.37
2.54
3.6
2.7
22.18
24.13
%
0.78
118
904
17
76
2.26
2.45
3.0
1.8
11.31
10.76
%
0.17
17
76
32
182
1.79
2.43
1.2
1.2
—
—
—
0
0
220
1830
1.28
2.42
1.8
1.7
17.78
19.82
nmol/l
1.61
193
1580
287
2464
1.25
2.41
5.2
3.5
7.70
8.36
mmol/l
1.48
254
2126
130
1011
1.34
2.34
1.7
1.7
1204.68
1156.17
nmol/l
0.27
100
802
508
4651
1.24
2.33
4.9
4.3
—
3.26
—
0
6
141
1113
1.32
2.30
4.0
3.1
2.70
1.72
e6/l
0.59
72
554
102
771
1.37
2.21
2.2
2.9
1.84
1.80
%
0.15
95
702
410
3694
1.22
2.11
7.6
6.8
2.14
1.99
e9/l
0.36
369
3292
704
7308
0.76
2.11
15.4
11.9
31.39
28.81
u/l
1.98
692
7158
9
32
2.83
2.00
3.9
4.7
—
—
—
0
0
45
298
1.54
1.97
1.6
1.4
28.94
25.32
iu/l
0.20
37
253
19
99
1.94
1.91
4.4
6.5
10.94
10.62
mg/l
0.12
14
91
44
293
1.53
1.89
1.9
2.3
19.59
21.17
s
1.70
37
264
90
687
1.35
1.86
2.7
2.4
0.19
0.22
g/l
1.88
85
647
411
3741
1.20
1.81
9.1
7.1
0.19
0.20
e9/l
0.18
364
3316
400
3632
1.20
1.81
7.7
6.7
0.04
0.04
e9/l
0.67
348
3151
399
3623
1.20
1.80
7.7
6.7
0.62
0.59
e9/l
1.63
349
3142
271
2378
1.21
1.76
7.9
6.7
—
—
—
0
0
20
110
1.84
1.74
1.4
2.7
—
—
—
0
0
144
1184
1.26
1.73
2.1
1.7
—
—
—
0
0
20
111
1.82
1.70
1.3
1.7
—
—
—
0
0
20
111
1.82
1.70
1.3
1.7
—
—
—
0
0
20
111
1.82
1.70
1.3
1.7
—
—
—
0
0
20
111
1.82
1.70
1.3
1.7
—
—
—
0
0
137
1124
1.26
1.68
3.5
2.7
12.74
13.71
umol/l
0.79
130
1061
64
471
1.39
1.67
3.4
3.2
197.00
189.47
ng/l
0.06
56
425
225
1949
1.21
1.66
3.3
3.3
1848.82
1196.26
ng/l
0.46
190
1649
8
31
2.60
1.66
2.8
1.6
—
—
—
0
0
200
1715
1.22
1.64
2.7
2.2
2.85
2.86
mg/l
0.01
178
1495
316
2829
1.19
1.63
4.2
3.4
0.05
0.03
estimate
0.15
64
659
106
846
1.29
1.62
4.2
3.0
15.67
7.57
umol/l
0.94
94
763
36
239
1.53
1.60
1.3
1.2
41.67
92.40
titre
—
6
25
299
2671
1.19
1.57
4.5
3.6
41.98
62.33
ng/l
0.40
216
1855
77
594
1.33
1.51
2.4
3.0
79.67
71.10
e9/l
1.19
54
443
7
27
2.61
1.51
1.4
2.9
—
—
—
0
0
328
2961
1.18
1.51
2.7
2.4
70.50
74.61
nmol/l
1.88
307
2693
6
21
2.87
1.50
6.0
6.7
26.95
26.82
mmol/l
—
6
21
270
3017
0.84
1.50
2.1
2.0
1.57
1.43
mmol/l
1.47
237
2612
15
80
1.89
1.45
1.9
1.8
—
—
—
0
0
373
3412
1.17
1.45
7.9
6.9
27.97
27.76
%
0.14
359
3259
28
180
1.57
1.44
1.6
1.2
—
—
—
0
0
19
313
0.60
1.42
1.1
1.1
—
0.74
—
0
32
144
1212
1.23
1.42
3.1
2.9
2.45
2.44
mmol/l
0.21
124
1096
64
829
0.75
1.39
1.5
1.4
—
—
—
0
0
26
166
1.58
1.38
2.3
2.2
129.60
130.83
g/l
0.08
20
138
27
175
1.56
1.36
1.4
1.3
344.05
269.85
u/ml
0.67
22
106
232
2604
0.85
1.33
2.2
2.1
—
—
—
0
0
33
225
1.49
1.33
1.6
1.4
209.81
283.27
ug/g
1.03
18
134
15
83
1.82
1.32
1.6
1.4
19.39
28.24
ng/l
0.97
15
83
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
184
1601
1.19
1.29
1.7
1.9
1.24
1.14
mg/l
0.14
143
1245
364
3347
1.16
1.28
7.7
6.8
57.52
57.11
%
0.29
355
3222
88
710
1.27
1.27
1.7
1.8
—
—
—
0
0
21
327
0.63
1.27
1.1
1.1
1.43
1.51
g/l
0.76
21
327
5
19
2.64
1.21
1.4
1.2
—
—
—
0
0
23
148
1.57
1.21
2.3
1.8
—
—
—
0
0
360
3329
1.14
1.14
7.9
7.0
8.88
8.96
%
0.21
344
3155
7
30
2.34
1.12
1.4
1.7
242.81
56.95
ug/l
—
7
30
8
41
1.96
1.09
6.5
4.3
0.38
0.78
index
—
8
41
23
337
0.67
1.07
1.3
1.1
0.89
0.91
g/l
0.18
23
337
24
162
1.50
1.05
2.4
3.3
1.97
1.55
mmol/l
0.95
24
157
12
67
1.80
1.05
1.1
1.1
—
—
—
0
0
74
601
1.25
1.04
1.7
1.6
—
—
—
0
0
28
196
1.44
1.03
1.3
1.1
—
—
—
0
0
32
230
1.41
1.03
10.7
9.4
—
—
—
0
0
11
61
1.81
0.98
1.0
1.1
71.45
108.84
pmol/l
1.38
11
61
20
295
0.67
0.98
1.3
1.2
—
—
—
0
0
5
23
2.18
0.98
1.4
3.3
—
—
—
0
0
40
302
1.34
0.97
1.1
1.5
—
13.14
—
0
10
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
242
2201
1.14
0.96
3.8
3.6
2.34
2.35
mmol/l
0.31
227
2031
21
141
1.50
0.95
5.0
4.7
3.07
2.52
mmol/l
0.39
12
100
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
0
32
0.00
0.95
0.0
1.3
—
117.95
—
0
23
108
923
1.20
0.95
1.6
1.5
—
—
—
0
0
356
3325
1.12
0.92
8.0
7.0
0.70
0.68
%
0.29
342
3141
19
126
1.52
0.92
1.7
1.2
—
—
—
0
0
67
548
1.24
0.91
1.3
1.2
—
—
—
0
0
61
494
1.25
0.90
5.3
3.4
7.41
7.42
ph
0.45
55
418
211
1913
1.14
0.87
2.7
2.9
350.47
351.52
umol/l
0.05
184
1726
32
238
1.36
0.87
5.8
3.4
1.82
1.45
mg/l
1.21
32
219
313
2912
1.12
0.85
2.3
2.0
91.86
95.74
pmol/l
0.89
170
1624
355
3332
1.11
0.82
8.0
6.9
2.78
2.88
%
0.37
339
3153
103
1186
0.85
0.82
1.3
1.3
6.94
13.91
u/ml
0.71
34
485
104
900
1.18
0.81
1.5
1.3
—
—
—
0
0
28
373
0.74
0.80
1.6
1.7
—
—
—
0
0
36
277
1.31
0.80
3.2
3.7
594.20
4326.28
u/ml
0.53
30
240
0
25
0.00
0.79
0.0
1.2
—
828.57
—
0
7
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
48
592
0.80
0.78
3.6
4.4
7.38
7.34
ph
1.22
40
443
82
700
1.19
0.76
2.4
2.2
384.51
374.09
nmol/l
0.16
72
655
18
124
1.46
0.75
1.2
1.3
—
—
—
0
0
61
507
1.22
0.74
5.4
3.4
5.32
5.13
kpa
0.73
61
494
610
6271
0.90
0.69
5.6
4.8
1.81
1.88
mu/l
0.96
571
5841
70
819
0.84
0.69
1.3
1.5
—
—
—
0
0
9
59
1.53
0.68
3.0
1.7
18.04
21.05
nmol/l
—
9
53
9
59
1.53
0.68
1.8
1.4
—
—
—
0
0
46
377
1.23
0.65
1.4
1.2
—
—
—
0
0
11
70
1.58
0.65
1.0
1.0
—
—
titre
—
0
0
21
280
0.74
0.63
1.0
1.1
—
—
—
0
0
43
352
1.23
0.62
1.1
1.1
—
89.18
—
0
11
72
621
1.17
0.62
1.9
2.0
0.00
0.02
estimate
0.50
18
139
5
30
1.67
0.61
1.8
1.9
2932.40
1016.87
e6/l
—
5
24
0
23
0.00
0.58
0.0
1.7
—
30.91
—
0
23
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
48
570
0.83
0.58
1.6
1.4
—
—
—
0
0
534
5172
1.09
0.57
4.4
3.9
14.68
14.64
pmol/l
0.14
496
4774
246
2306
1.09
0.56
5.0
4.2
15.79
9.53
mg/mmol
0.73
166
1490
85
959
0.87
0.55
2.5
2.4
13.60
13.65
nmol/l
0.02
78
880
54
460
1.19
0.55
1.4
1.2
108.54
140.31
u/ml
0.20
22
176
22
170
1.30
0.52
1.5
2.2
2.47
4.10
iu/l
—
6
69
6
40
1.50
0.51
1.0
3.3
501.50
564.15
u/ml
—
6
40
9
64
1.41
0.51
1.9
1.7
—
—
—
0
0
33
400
0.82
0.50
1.8
2.0
41.33
37.02
nmol/l
0.43
33
386
22
171
1.29
0.50
2.0
1.5
—
—
—
0
0
72
815
0.87
0.50
1.4
1.5
—
—
—
0
0
37
442
0.83
0.49
1.2
1.2
—
—
—
0
0
33
271
1.23
0.49
1.3
1.3
10.91
7.19
u/l
0.49
26
221
53
612
0.86
0.48
2.2
2.6
11.12
10.70
g/l
0.16
48
569
118
1290
0.90
0.47
1.4
1.3
26.00
30.03
iu/ml
0.27
38
398
81
905
0.88
0.47
5.2
3.6
6.39
5.03
e9/l
0.27
76
803
23
183
1.26
0.45
1.6
1.5
22759.89
12410.25
e6/l
0.32
18
133
32
265
1.22
0.45
1.0
1.3
—
—
—
0
0
10
69
1.45
0.44
2.3
2.8
8.80
15.96
mg/l
—
5
52
337
3231
1.07
0.44
3.4
3.0
119.18
139.14
ug/l
1.08
319
3051
329
3153
1.07
0.43
14.0
11.4
0.00
0.00
e9/l
0.31
267
2605
8
56
1.43
0.42
1.3
1.4
16.25
27.57
%
—
8
38
13
96
1.36
0.41
1.3
1.2
—
—
—
0
0
8
58
1.38
0.41
2.1
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
17
0.00
0.40
0.0
2.8
—
41.59
—
0
17
0
17
0.00
0.40
0.0
5.6
—
8.71
—
0
17
5
34
1.47
0.40
1.0
1.2
122.00
193.99
mmol/24h
—
5
34
32
269
1.20
0.40
1.4
1.3
—
—
—
0
0
20
160
1.26
0.39
2.1
1.4
141.60
154.60
au/ml
—
5
54
40
348
1.16
0.35
1.7
2.2
0.00
2.12
estimate
0.51
13
120
15
117
1.29
0.35
1.7
1.6
—
—
—
0
0
10
134
0.74
0.35
3.6
4.1
—
—
—
0
0
24
286
0.83
0.34
1.7
1.7
893.29
923.23
mu/l
0.09
19
255
6
45
1.34
0.34
2.2
3.2
15.02
16.44
%
—
6
45
15
188
0.79
0.33
1.1
1.2
—
—
—
0
0
21
252
0.83
0.32
2.0
2.4
16.91
46.92
u/ml
1.90
21
239
11
83
1.33
0.32
1.9
2.3
—
—
—
0
0
15
119
1.27
0.32
1.7
1.7
—
—
—
0
0
693
7011
0.93
0.31
28.9
17.8
3.97
3.98
mmol/l
0.23
685
6878
49
441
1.12
0.28
1.1
1.1
—
—
—
0
0
30
261
1.16
0.28
2.1
2.5
—
—
—
0
0
69
634
1.10
0.28
5.1
5.1
1.41
0.84
%
0.84
32
221
10
128
0.78
0.27
9.5
3.5
21.21
9.13
pmol/l
—
10
128
31
272
1.15
0.26
2.6
1.7
—
—
—
0
0
5
74
0.67
0.26
2.0
1.5
236.28
159.34
pmol/l
—
5
74
235
2267
1.05
0.25
4.3
3.6
77.20
58.04
mg/l
0.45
163
1509
24
276
0.87
0.24
4.6
3.9
24.71
24.85
mmol/l
0.12
24
263
514
5052
1.05
0.24
5.7
3.4
68.13
51.08
u/l
2.14
495
4833
10
78
1.29
0.24
2.3
2.6
1.87
1.52
g/24h
—
5
52
693
6993
0.95
0.22
29.0
17.7
139.25
139.69
mmol/l
4.20
686
6869
10
79
1.27
0.22
1.0
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
0.56
—
0
10
5
41
1.22
0.22
1.0
1.0
2640.20
1492.80
miu/ml
—
5
41
0
11
0.00
0.21
0.0
1.8
—
10.67
—
0
6
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
11.9
—
0.42
—
0
10
0
10
0.00
0.21
0.0
6.0
—
8.05
—
0
10
0
12
0.00
0.21
0.0
1.1
—
0.02
—
0
12
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
6.53
—
0
14
46
499
0.92
0.19
6.6
3.9
1.20
1.22
mmol/l
1.72
41
438
208
2145
0.96
0.19
1.5
1.5
—
—
—
0
0
21
237
0.88
0.18
1.0
1.4
235.32
228.25
miu/ml
—
5
112
20
176
1.14
0.17
2.8
2.4
413.04
83.71
ug/min
0.52
11
104
8
68
1.18
0.16
1.9
1.4
—
—
—
0
0
16
183
0.87
0.16
2.2
3.8
1.61
2.54
ratio
—
5
99
11
130
0.84
0.16
1.1
1.5
—
—
—
0
0
168
1628
1.04
0.16
1.5
1.3
1.40
1.98
u/ml
0.52
43
485
8
73
1.10
0.15
3.1
2.5
—
—
—
0
0
6
76
0.79
0.15
1.7
3.3
6.93
73.29
nmol/l
—
6
76
18
159
1.14
0.15
1.1
1.1
—
—
—
0
0
37
343
1.08
0.14
3.9
3.7
—
—
—
0
0
15
131
1.15
0.14
3.5
3.1
5.20
4.20
e9/l
0.53
15
131
22
243
0.90
0.14
1.7
1.6
28.26
10.69
u/ml
—
5
61
9
106
0.85
0.13
1.0
1.2
—
—
—
0
0
10
116
0.86
0.12
1.4
1.3
—
—
—
0
0
91
878
1.04
0.11
1.4
1.3
—
—
—
0
0
39
414
0.94
0.11
1.9
2.7
—
—
—
0
0
63
605
1.04
0.09
4.4
5.0
1.30
0.61
%
0.97
27
202
6
55
1.09
0.09
1.2
1.0
—
—
—
0
0
18
165
1.09
0.08
4.0
3.3
60.61
57.71
%
0.59
18
165
15
136
1.10
0.08
1.0
1.1
7.11
6.74
u/ml
—
8
69
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
7
64
1.09
0.08
1.3
1.1
—
—
—
0
0
6
71
0.84
0.07
1.0
1.4
—
—
—
0
0
6
75
0.80
0.07
1.5
3.9
58.83
54.91
%
—
6
70
6
75
0.80
0.07
1.2
1.2
—
—
nmol/l
—
0
0
15
162
0.92
0.06
1.0
1.1
2.20
2.30
u/ml
—
8
91
14
129
1.09
0.05
1.0
1.1
0.84
1.28
u/ml
—
6
63
11
100
1.10
0.05
1.2
1.1
—
—
—
0
0
11
100
1.10
0.05
2.5
3.3
—
—
—
0
0
14
130
1.08
0.04
1.0
1.1
1.05
1.16
u/ml
—
5
56
65
665
0.98
0.04
3.9
4.8
8.28
29.95
ug/l
0.96
55
547
52
534
0.97
0.04
2.6
2.2
6.05
6.06
ph
0.02
39
352
16
150
1.07
0.04
1.0
1.1
—
—
—
0
0
13
121
1.08
0.03
1.0
1.0
5.11
1.79
u/ml
—
5
58
14
131
1.07
0.03
1.4
1.4
—
—
—
0
0
103
1016
1.02
0.03
1.3
1.4
440.00
482.55
titre
0.13
16
220
10
92
1.09
0.03
2.0
2.3
—
—
—
0
0
92
930
0.99
0.02
2.8
2.6
162.13
118.84
ug/g
0.29
80
765
10
93
1.08
0.02
1.2
1.1
—
—
—
0
0
55
559
0.98
0.02
4.0
3.7
—
—
—
0
0
146
1470
0.99
0.01
1.5
1.4
2.95
2.50
g/l
1.15
81
968
16
153
1.05
0.01
1.1
1.1
—
—
—
0
0
16
153
1.05
0.01
1.1
1.1
—
—
—
0
0
15
156
0.96
0.00
2.7
4.6
—
—
—
0
0
30
306
0.98
0.00
2.0
2.3
—
—
—
0
0
60
606
0.99
0.00
5.8
5.7
0.04
0.15
%
0.81
23
169
11
115
0.96
0.00
1.0
1.0
0.92
2.56
eliau/ml
—
5
52
12
124
0.97
0.00
1.1
1.2
—
—
—
0
0
23
235
0.98
0.00
4.0
4.6
428.70
322.94
mg/l
—
10
119
15
154
0.97
0.00
1.0
1.4
—
—
—
0
0
11
112
0.98
0.00
2.1
4.1
1.09
1.29
%
0.17
11
106
39
393
0.99
0.00
2.7
3.7
4.48
4.65
pmol/l
0.57
33
356
687
6866
1.00
0.00
24.3
15.5
28.11
24.34
mg/l
2.19
593
5635
169
1686
1.00
0.00
5.0
4.9
—
—
—
0
0
12
119
1.01
0.00
2.3
2.0
14.00
13.23
%
0.54
12
119
210
2097
1.00
0.00
3.5
3.0
0.00
0.06
estimate
0.77
57
616
60
598
1.00
0.00
5.6
5.3
0.35
0.16
%
0.70
23
183
0
8
0.00
0.00
0.0
1.6
—
155.38
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
0.00
1.9
2.8
1.04
0.90
%
—
8
59
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.6
62.33
79.39
umol/l
—
6
59
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
5
55
0.91
-0.00
1.2
1.1
—
—
—
0
0
9
90
1.00
-0.00
1.8
2.9
33.67
33.39
pg
—
9
90
0
7
0.00
-0.00
0.0
3.4
—
0.20
—
0
7
6
62
0.97
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
84.62
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
60
1.00
-0.00
1.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.93
—
0
6
0
5
0.00
-0.00
0.0
5.4
—
16.48
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint ST19_TOXIC_EFFECT_ALCOHOL and mortality.

Females

Parameter HR [95% CI] p-value
ST19_TOXIC_EFFECT_ALCOHOL 4.993 [3.52, 7.08] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 999 females with ST19_TOXIC_EFFECT_ALCOHOL died.

Males

Parameter HR [95% CI] p-value
ST19_TOXIC_EFFECT_ALCOHOL 5.096 [4.25, 6.11] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 587 out of 2166 males with ST19_TOXIC_EFFECT_ALCOHOL died.

Mortality risk

Mortality risk for people of age

years, who have ST19_TOXIC_EFFECT_ALCOHOL.

N-year risk Females Males
1 0.512% 0.933%
5 2.421% 5.27%
10 6.017% 13.689%
15 11.05% 24.353%
20 18.141% 38.048%

Relationships between endpoints

↥

Index endpoint: ST19_TOXIC_EFFECT_ALCOHOL – Toxic effect of alcohol

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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