No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
825 |
4. Check minimum number of eventsNone |
825 |
5. Include endpointsNone |
825 |
6. Filter based on genotype QC (FinnGen only) |
806 |
Control definitions (FinnGen only)
- Control exclude
- ST19_TOXIC_EFFEC_SUBST_CHIEF_NONME_SOURCE
Extra metadata
- Level in the ICD hierarchy
- 3
- Special
- ALCOTOXIC
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T51-T65
- Name in latin
- Effectus alcoholicus toxicus
Similar endpoints
↥List of similar endpoints to
Toxic effect of alcohol
based on the number of shared cases.
Similar with more cases:
- Toxic effects of substances chiefly nonmedicinal as to source
- Alcohol use disorder, Swedish definition
- Alcohol related diseases and deaths, all endpoints
- Injury, poisoning and certain other consequences of external causes
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10946 | 3014 | 7772 |
| Only index persons | 7769 | 2497 | 5272 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.09 | 0.22 |
| Only index persons | 0.17 | 0.09 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 28.20 | 21.94 | 30.22 |
| Only index persons | 22.55 | 19.17 | 24.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 806 | 298 | 508 |
| Unadjusted period prevalence (%) | 0.19 | 0.11 | 0.23 |
| Median age at first event (years) | 25.59 | 20.60 | 28.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 825
- Matched controls
- 8250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
98000
ICD-8 Finland
Toxic effect of alcohol, Ethyl alcohol
+∞
307.7
427
*
T51.9
ICD-10 Finland
Toxic effect: Alcohol, unspecified
+∞
166.4
154
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
16.4
158.2
142
103
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.9
155.2
230
344
T36
ICD-10 Finland
Poisoning by systemic antibiotics
12.1
135.3
147
145
E8699
ICD-8 Finland
Accidental poisoning by other and unspecified solid and liquid substances
252.0
127.8
128
6
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
65.1
119.2
66
11
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
21.9
109.3
83
42
X45
ICD-10 Finland
Accidental poisoning by and exposure to alcohol
182.9
108.2
111
7
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
49.0
94.0
55
12
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
13.6
86.8
84
68
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
25.9
82.4
58
24
30310
ICD-8 Finland
Alcoholism, Habitual excessive drinking
44.2
76.8
46
11
T51.0
ICD-10 Finland
Toxic effect: Ethanol
+∞
75.2
71
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
11.5
74.5
80
76
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
18.1
68.4
56
33
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
8.3
67.0
93
124
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
18.0
65.7
54
32
T51.8
ICD-10 Finland
Toxic effect: Other alcohols
+∞
65.5
62
*
98099
ICD-8 Finland
Toxic effect of alcohol, Other
+∞
62.3
59
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
10.7
62.1
70
71
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
12.1
60.2
62
55
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
17.1
59.4
50
31
N07BB01
ATC
disulfiram; oral
6.2
58.5
109
199
T51.1
ICD-10 Finland
Toxic effect: Methanol
+∞
55.9
53
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
9.4
51.1
63
72
N05AA02
ATC
levomepromazine; systemic
6.0
48.2
90
164
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
12.1
46.8
48
42
F10.24
ICD-10 Finland
Alcohol depence active use
9.5
45.9
56
63
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
13.7
45.4
43
33
V03AA01, ,
ATC
10.1
41.6
48
50
P15
ICPC
Chronic alcohol abuse
6.0
40.6
75
135
P16
ICPC
Acute alcohol abuse
8.6
39.7
52
64
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
12.0
39.0
40
35
N05BA01
ATC
diazepam; systemic, rectal
3.4
38.5
166
574
N05BA02
ATC
chlordiazepoxide; systemic
6.8
38.1
62
98
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
35.2
162
581
E9809
ICD-8 Finland
Poisoning by solid or liquid substances, undetermined whether accidentally or purposely inflicted, Other and unspecified solid and liquid substances
188.0
35.0
36
*
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
10.2
35.0
40
41
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
9.1
33.0
41
47
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.7
30.9
108
324
N05AH04
ATC
quetiapine; oral
2.7
29.5
204
906
N05AB01
ATC
dixyrazine; systemic
9.6
29.3
35
38
N05CD07
ATC
temazepam; oral
3.1
29.0
134
479
N05BA04
ATC
oxazepam; oral
2.5
28.8
250
1237
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.1
28.2
35
40
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
10.7
28.2
31
30
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
28.1
76
189
30041
ICD-8 Finland
Neuroses, Depressiva
10.0
26.9
31
32
N06AX11
ATC
mirtazapine; oral
2.3
26.7
321
1817
K92.0
ICD-10 Finland
Haematemesis
6.2
26.3
46
78
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
8.3
26.2
35
44
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.7
24.8
35
47
N03AG01
ATC
valproic acid; systemic, rectal
3.7
24.5
82
238
T51.2
ICD-10 Finland
Toxic effect: 2-Propanol
+∞
24.1
23
*
N06AB04
ATC
citalopram; systemic
2.4
24.0
200
961
N05AF03
ATC
chlorprothixene; systemic
5.4
23.9
48
93
N05CF01
ATC
zopiclone; oral
2.2
23.7
295
1677
Z72.1
ICD-10 Finland
Alcohol use
7.3
22.2
33
47
N06AB03
ATC
fluoxetine; oral
2.7
21.3
130
536
WX730
NOMESCO Finland
Conventional respirator
9.2
21.3
26
29
S06.0
ICD-10 Finland
Concussion
2.8
21.2
117
458
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.9
20.9
29
38
30180
ICD-8 Finland
Personality disorders, Immatura
31.0
20.7
27
9
N05AD01
ATC
haloperidol; systemic
5.0
20.6
45
94
30399
ICD-8 Finland
Other and unspecified alcoholism
59.0
20.0
23
*
85000
ICD-8 Finland
Concussion, Current or unspecified
5.3
20.0
41
81
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
18.5
157
753
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.8
18.2
42
92
Y91.1
ICD-10 Finland
Moderate alcohol intoxication
+∞
17.8
17
*
9809X
ICD-9 Finland
Toxic effect of alcohol, Unspecified alcohol
+∞
17.8
17
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.8
17.3
90
340
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
17.3
145
691
Y19
ICD-10 Finland
Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent
32.2
17.1
22
7
R40.2
ICD-10 Finland
Coma, unspecified
13.0
16.7
29
23
F61.0
ICD-10 Finland
Mixed personality disorders
5.8
16.4
30
53
E8599
ICD-8 Finland
Accidental poisoning by other and unspecified drugs and medicaments, Drugs, unspecified
41.0
16.4
20
5
N05AH03
ATC
olanzapine; systemic
3.0
16.4
78
281
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
16.4
254
1529
N05BE01
ATC
buspirone; oral
4.1
16.3
46
118
N05AH02
ATC
clozapine; systemic
4.8
16.2
37
80
Z2446
NOMESCO Finland
Social worker
3.0
15.8
73
258
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
3.8
15.7
49
135
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.7
15.6
29
52
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.9
15.6
76
277
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.4
15.1
38
89
N06AX03
ATC
mianserin; oral
3.5
14.9
53
160
N05AB03
ATC
perphenazine; systemic, rectal
3.7
14.7
48
137
T65.9
ICD-10 Finland
Toxic effect: Toxic effect of unspecified substance
152.6
14.5
15
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
14.4
141
714
E970A
ICD-9 Finland
Injury due to legal intervention by firearms
27.7
14.3
19
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
14.3
211
1240
E9599
ICD-8 Finland
Late effect of self-inflicted injury
30.6
13.9
18
6
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.5
13.6
95
415
F10.07
ICD-10 Finland
Pathological alcohol intoxication
76.4
13.6
15
*
E850A
ICD-9 Finland
Accidental poisoning by analgesics, antipyretics, antirheumatics
76.4
13.6
15
*
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
5.4
13.3
26
49
N06AB06
ATC
sertraline; oral
2.3
13.2
107
500
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.4
13.0
33
78
9800A
ICD-9 Finland
Toxic effect of alcohol, Ethyl alcohol
28.9
13.0
17
6
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.3
12.8
49
155
A06AD11
ATC
lactulose; oral
2.2
12.7
122
612
N06AA12
ATC
doxepin; systemic
3.0
12.5
57
200
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
131.9
12.5
13
*
N04AA02
ATC
biperiden; systemic
4.7
12.4
29
64
AA1AD
NOMESCO Finland
CT of head and brain
1.8
12.4
214
1316
SPAT1265
SPAT
Breathalyser
5.9
12.3
22
38
Y91.2
ICD-10 Finland
Severe alcohol intoxication
38.2
12.2
15
*
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
21.7
12.0
17
8
N05CD02
ATC
nitrazepam; oral
5.2
11.8
24
47
N06AB05
ATC
paroxetine; oral
2.8
11.8
60
224
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
11.7
169
981
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
11.6
41
123
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
8.5
11.4
24
29
97010
ICD-8 Finland
Adverse effect of psychotherapeutics, Tranquillisers
35.6
11.3
14
*
N06AX16
ATC
venlafaxine; oral
2.0
11.1
123
650
P29
ICPC
Psychological sympt/compl other
2.5
11.1
69
286
N05BA12
ATC
alprazolam; oral
2.3
11.0
90
421
N05AX12
ATC
aripiprazole; systemic
3.1
10.9
47
160
30188
ICD-8 Finland
Personality disorders, Alia definita
12.1
10.9
19
16
P99
ICPC
Psychological disorders other
3.6
10.8
36
104
96798
ICD-8 Finland
Other sleeping pills and sedatives
28.4
10.7
14
5
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.9
10.7
51
184
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
11.4
10.6
19
17
N07BA03
ATC
varenicline; oral
2.8
10.5
53
197
N02AX02
ATC
tramadol; systemic, rectal
1.6
10.5
345
2515
N06AB10
ATC
escitalopram; oral
1.8
10.5
174
1052
30199
ICD-8 Finland
Personality disorders, Unspecified
111.4
10.4
11
*
29120
ICD-8 Finland
Alcoholic psychosis, Other alcoholic hallucinosis
111.4
10.4
11
*
Y91.0
ICD-10 Finland
Mild alcohol intoxication
+∞
10.4
10
*
98020
ICD-8 Finland
Toxic effect of alcohol, Isopropyl alcohol
+∞
10.4
10
*
N05AD03
ATC
melperone; systemic
7.9
10.4
23
30
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.4
10.4
26
61
5353A
ICD-9 Finland
Gastritis and duodenitis, Alcoholic gastritis
33.0
10.3
13
*
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
5.0
10.3
22
45
2918A
ICD-9 Finland
Alcoholic psychoses, Other specified alcoholic psychosis
23.7
10.3
14
6
TKC20
NOMESCO Finland
Catheterisation of bladder
2.6
10.3
62
253
W19
ICD-10 Finland
Unspecified fall
2.3
10.3
83
387
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
8.6
10.1
21
25
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
10.1
82
383
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.0
10.1
44
151
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.2
10.0
90
438
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
12.4
9.9
17
14
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
12.4
9.9
17
14
N05AX08
ATC
risperidone; systemic
2.3
9.8
77
354
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
8.9
9.8
20
23
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
8.0
9.7
21
27
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
9.6
46
166
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.6
345
2555
E9609
ICD-8 Finland
Fight, brawl, rape
11.5
9.6
17
15
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
9.2
9.6
19
21
R51.80
ICD-10 Finland
Headache
1.9
9.6
126
706
N05AC02
ATC
thioridazine; oral
4.2
9.5
25
61
C03CA01
ATC
furosemide; systemic
1.7
9.5
199
1285
S01.0
ICD-10 Finland
Open wound of scalp
2.3
9.4
71
321
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
8.2
9.4
20
25
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
5.0
9.3
20
41
N03AF01
ATC
carbamazepine; oral, rectal
2.7
9.3
50
192
N05AA01
ATC
chlorpromazine; systemic, rectal
4.8
9.3
21
45
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
9.7
9.3
18
19
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
13.9
9.2
15
11
C07AA05
ATC
propranolol; systemic
1.8
9.2
162
994
WX892
NOMESCO Finland
Monitored bed care
2.4
9.2
67
299
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
4.5
9.1
22
50
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
4.9
9.1
20
42
F60.2
ICD-10 Finland
Dissocial personality disorder
15.8
9.1
14
9
N03AX09
ATC
lamotrigine; oral
2.7
9.0
47
178
F10.02
ICD-10 Finland
Alcohol-related acute intoxication with other acute clinical complications
24.3
8.9
12
5
N05AN01
ATC
lithium; oral
3.6
8.9
29
83
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
8.8
49
192
TK800
NOMESCO Finland
Hemodialysis
3.7
8.8
27
74
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
8.7
77
372
97920
ICD-8 Finland
Alcohol in combination with specified medicinal agents, With nonbarbiturate sedatives
50.5
8.7
10
*
29100
ICD-8 Finland
Alcoholic psychosis, Delirium tremens
50.5
8.7
10
*
E87.2
ICD-10 Finland
Acidosis
10.2
8.6
16
16
97940
ICD-8 Finland
Alcohol in combination with specified medicinal agents, With psychopharmacological agents
27.8
8.5
11
*
98098
ICD-8 Finland
Toxic effect of alcohol, Other alcohols
+∞
8.3
8
*
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
10.9
8.3
15
14
R41.0
ICD-10 Finland
Disorientation, unspecified
3.6
8.3
27
77
K70.1
ICD-10 Finland
Alcoholic hepatitis
9.6
8.3
16
17
92000
ICD-8 Finland
Contusion of face, scalp and neck except eye(s), Current injury
9.6
8.3
16
17
T74.1
ICD-10 Finland
Physical abuse
3.9
8.3
24
63
K29.2
ICD-10 Finland
Alcoholic gastritis
14.6
8.2
13
9
X84
ICD-10 Finland
Intentional self-harm by unspecified means
14.6
8.2
13
9
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.9
8.2
37
130
SPAT1247
SPAT
Outpatient detoxication and monitoring
11.8
8.1
14
12
N02BF02
ATC
pregabalin; oral
2.5
8.0
49
202
F10.05
ICD-10 Finland
Alcohol-related acute intoxication with coma
13.2
7.9
13
10
30088
ICD-8 Finland
Neuroses, Other
13.2
7.9
13
10
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
7.9
105
590
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
8.6
7.8
16
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.8
263
1901
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
7.8
72
355
P01
ICPC
Feeling anxious/nervous/tense
2.0
7.7
93
504
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.3
7.7
29
91
F05.9
ICD-10 Finland
Delirium, unspecified
4.0
7.6
21
53
V03AB30, ,
ATC
6.8
7.6
18
27
Y90.8
ICD-10 Finland
Blood alcohol level of 240 mg/100 ml or more
25.3
7.6
10
*
Z91.5
ICD-10 Finland
Personal history of self-harm
25.3
7.6
10
*
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.2
7.6
20
49
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.6
7.5
24
68
A98
ICPC
Health maint/preventive medicine
0.6
7.4
680
7338
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.4
139
865
P19
ICPC
Drug abuse
8.5
7.3
15
18
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
7.3
71
356
X65
ICD-10 Finland
Intentional self-poisoning by and exposure to alcohol
+∞
7.3
7
*
T51
ICD-10 Finland
Toxic effect of alcohol
+∞
7.3
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
7.3
162
1055
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.9
7.2
34
122
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
15.9
7.2
11
7
30799
ICD-8 Finland
Transient situational disturbances
15.9
7.2
11
7
P18
ICPC
Medication abuse
7.4
7.2
16
22
N05CF02
ATC
zolpidem; oral
1.7
7.2
132
816
30430
ICD-8 Finland
Drug dependence, Other hypnotics and sedatives or tranquillisers
30.3
7.2
9
*
F10.4
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state with delirium
20.2
7.1
10
5
Z72.0
ICD-10 Finland
Tobacco use
3.1
7.1
29
96
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
10.1
7.0
13
13
SPAT1227
SPAT
Substance abuse rehabilitation
7.6
6.9
15
20
Z72.2
ICD-10 Finland
Drug use
13.9
6.9
11
8
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
9.4
6.8
13
14
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.1
6.8
27
88
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.3
6.7
25
78
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
6.7
91
514
N03AE01
ATC
clonazepam; systemic
2.3
6.6
49
220
X78
ICD-10 Finland
Intentional self-harm by sharp object
7.9
6.6
14
18
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
6.6
48
214
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.5
6.6
39
158
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
3.5
6.6
22
64
Z72.8
ICD-10 Finland
Other problems related to lifestyle
12.4
6.6
11
9
A46
ICD-10 Finland
Erysipelas
1.8
6.6
113
685
Y07
ICD-10 Finland
Other maltreatment
6.9
6.5
15
22
N06AA06
ATC
trimipramine; systemic
3.1
6.5
26
85
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
4.0
6.5
18
46
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.4
6.5
23
70
T58
ICD-10 Finland
Toxic effect of carbon monoxide
70.4
6.4
7
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.0
6.4
27
91
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
14.4
6.4
10
7
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
3.8
6.4
19
51
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.2
6.4
25
81
AA400
NOMESCO Finland
Electroconvulsive therapy
6.6
6.4
15
23
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.2
6.3
13
16
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.0
6.3
16
27
30398
ICD-8 Finland
Alcoholism, Alius definitus
+∞
6.3
6
*
9808X
ICD-9 Finland
Toxic effect of alcohol, Other specified alcohols
+∞
6.3
6
*
98090, ,
ICD-8 Finland
+∞
6.3
6
*
30488
ICD-8 Finland
Drug dependence, Other
+∞
6.3
6
*
9802A
ICD-9 Finland
Toxic effect of alcohol, Isopropyl alcohol
+∞
6.3
6
*
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.7
6.2
19
52
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
6.1
54
262
WX110, ,
SPAT
2.2
6.1
51
242
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.6
6.1
19
53
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
6.1
6.0
15
25
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
58
57
10.87
52.50
3.7
1.4
1.94
1.15
promille
2.12
46
46
132
540
2.72
22.03
6.9
3.7
1.26
1.92
mmol/l
0.85
110
442
144
692
2.31
16.81
10.3
9.1
0.97
1.11
mmol/l
0.14
117
550
27
45
6.17
15.67
1.9
1.5
—
—
—
0
0
30
58
5.33
14.95
25.3
16.1
1361.17
1463.40
nmol/l
0.26
30
58
26
21
12.74
14.95
9.0
1.9
84.17
90.67
umol/l
0.07
12
12
120
585
2.23
13.39
11.7
9.9
123.17
122.91
g/l
0.05
120
570
39
107
3.78
12.61
4.0
5.4
425.56
352.06
umol/l
1.71
32
94
318
2202
1.72
12.25
4.4
3.4
38.30
34.53
u/l
0.71
300
2097
291
1994
1.71
11.48
4.2
2.6
56.18
60.76
u/l
0.74
276
1874
173
1017
1.89
11.46
3.0
1.9
1.68
1.50
%
2.52
160
894
428
3279
1.63
10.75
7.4
6.6
10.93
11.48
umol/l
0.61
407
3118
275
1886
1.69
10.65
2.9
2.1
349.66
294.53
u/l
0.24
270
1791
80
380
2.22
9.45
9.0
8.5
24.30
24.53
mmol/l
0.17
80
358
120
681
1.89
8.73
2.0
1.8
—
—
—
0
0
120
689
1.87
8.41
2.1
1.9
—
—
—
0
0
161
1013
1.73
8.31
4.2
3.8
0.77
0.82
mmol/l
5.04
152
959
346
2653
1.52
7.81
11.8
6.3
1.19
1.21
mmol/l
3.35
331
2445
102
583
1.86
7.23
5.0
2.5
81.64
122.95
u/l
0.18
87
502
13
13
10.14
7.05
1.2
1.1
—
—
—
0
0
369
2933
1.47
6.67
10.2
7.1
1.20
1.21
mmol/l
3.20
332
2509
47
208
2.34
6.59
7.0
4.3
1.48
1.31
mmol/l
0.42
47
202
451
3740
1.45
6.45
8.7
5.0
7.10
6.70
mmol/l
2.77
435
3490
89
512
1.83
6.18
3.1
2.3
4.96
8.89
ug/l
2.95
81
464
356
2850
1.44
6.00
11.0
12.9
1.12
1.23
inr
2.43
98
846
170
1174
1.56
5.94
5.2
3.8
311.32
424.54
ng/l
0.27
129
895
291
2248
1.45
5.92
4.0
3.1
—
—
—
0
0
604
6626
0.67
5.77
4.7
4.2
4.56
4.66
mmol/l
1.72
564
6234
146
980
1.60
5.75
2.2
1.9
—
—
—
0
0
601
6595
0.67
5.69
4.5
4.2
1.37
1.40
mmol/l
0.99
560
6171
578
6374
0.69
5.40
4.2
3.8
1.46
1.36
mmol/l
1.96
535
5939
189
1378
1.48
5.06
5.3
3.3
1.01
1.02
kg/l
0.99
20
189
175
1263
1.49
4.92
2.9
2.4
5.81
5.05
e6/l
0.24
161
1137
553
4879
1.40
4.91
9.3
7.7
79.43
77.37
u/l
0.42
538
4621
243
1874
1.42
4.81
3.8
3.1
49.90
98.71
e6/l
0.64
189
1446
201
1497
1.45
4.81
2.7
2.3
—
—
—
0
0
621
6723
0.69
4.74
5.0
4.6
2.72
2.79
mmol/l
1.32
577
6284
123
1747
0.65
4.57
2.5
2.7
0.65
0.73
ug/l
0.79
86
1045
707
7455
0.64
4.55
30.9
19.3
253.75
247.70
e9/l
1.50
695
7281
708
7463
0.64
4.54
31.0
19.4
136.63
138.72
g/l
3.06
703
7365
708
7460
0.64
4.47
30.8
19.3
4.53
4.59
e12/l
2.54
692
7275
67
392
1.77
4.44
5.3
4.4
129.42
86.46
ng/l
0.92
58
351
312
2543
1.36
4.36
6.6
5.1
34.87
35.97
g/l
2.41
291
2399
708
7452
0.65
4.27
31.6
19.4
40.70
41.02
%
0.72
661
7015
427
3660
1.35
4.26
13.2
9.4
4.48
4.07
e9/l
3.06
380
3226
41
209
2.01
4.13
1.8
2.2
18059.59
2982.22
u/l
—
7
87
208
1599
1.40
4.11
7.4
3.9
89.25
90.81
%
0.39
202
1571
219
1701
1.39
4.07
3.8
2.9
0.49
0.48
e6/l
0.02
170
1284
250
1985
1.37
4.06
4.8
3.2
7.77
8.29
mmol/l
0.84
217
1701
44
769
0.55
3.77
1.6
1.8
—
—
—
0
0
13
34
3.87
3.70
2.8
1.7
—
—
—
0
0
592
6393
0.74
3.64
4.8
4.2
6.22
5.95
mmol/l
3.60
547
5895
189
2374
0.74
3.38
3.7
3.7
19.43
21.10
%
0.87
77
1009
45
255
1.81
3.36
6.3
7.2
2.39
1.60
%
2.05
45
239
23
102
2.29
3.31
1.5
1.3
—
—
—
0
0
23
102
2.29
3.31
1.5
1.3
—
—
—
0
0
10
23
4.39
3.31
1.8
4.0
—
—
—
0
0
10
23
4.39
3.31
1.8
4.0
—
—
—
0
0
287
2388
1.31
3.28
2.4
2.2
71.48
74.56
nmol/l
1.01
268
2149
246
2956
0.76
3.18
3.7
4.2
2.10
2.13
ug/l
0.03
218
2688
29
147
2.01
3.03
8.4
10.2
103.93
105.51
mmol/l
0.84
29
134
208
1672
1.33
3.01
4.4
3.4
0.00
0.01
estimate
1.08
56
591
115
841
1.43
2.99
3.2
2.5
2.30
2.34
g/l
0.30
104
785
364
3160
1.27
2.91
3.9
3.2
0.00
0.01
estimate
0.50
53
571
157
1216
1.36
2.90
1.6
1.7
430.08
36944323.11
pmol/l
1.43
134
1034
36
200
1.84
2.90
1.7
1.4
—
—
—
0
0
108
787
1.43
2.86
3.4
2.5
21.52
24.20
%
1.22
95
687
25
123
2.06
2.84
1.4
1.7
—
—
—
0
0
136
1034
1.38
2.82
3.5
2.7
1.01
0.97
e6/l
0.08
86
595
359
3123
1.26
2.79
4.0
3.2
0.00
0.00
estimate
0.50
61
640
90
637
1.46
2.79
4.0
3.3
—
—
—
0
0
169
1334
1.34
2.76
1.6
1.5
18.32
20.16
nmol/l
1.03
149
1150
358
3121
1.26
2.71
5.1
4.5
0.00
0.00
estimate
0.50
61
614
32
176
1.85
2.67
1.2
1.1
—
—
—
0
0
32
176
1.85
2.67
1.2
1.1
—
—
—
0
0
445
3993
1.25
2.57
5.5
3.9
181.11
2004.92
e6/l
—
9
62
58
382
1.56
2.53
1.7
1.4
—
—
—
0
0
20
95
2.13
2.50
1.4
1.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
33
189
1.78
2.44
3.9
3.0
0.31
0.33
u/ml
0.16
21
102
274
2349
1.25
2.32
2.1
1.9
90.16
95.32
pmol/l
1.18
147
1289
18
85
2.14
2.30
4.4
6.5
11.08
10.47
mg/l
0.24
13
78
129
1009
1.33
2.24
1.7
1.7
1197.23
1160.43
nmol/l
0.19
99
796
61
421
1.48
2.18
2.0
1.6
—
—
—
0
0
28
159
1.79
2.16
1.5
1.3
—
—
—
0
0
21
110
1.93
2.07
1.5
1.7
—
—
—
0
0
12
50
2.42
2.03
3.3
2.5
—
—
—
0
0
117
920
1.32
1.97
3.2
2.5
12.65
13.68
umol/l
0.74
110
866
5
11
4.57
1.94
11.6
6.5
—
—
—
0
0
55
382
1.47
1.93
2.0
2.0
—
—
—
0
0
53
366
1.48
1.91
1.7
1.6
—
—
—
0
0
123
978
1.30
1.91
3.8
2.9
2.76
1.74
e6/l
0.62
72
543
18
93
1.96
1.86
1.2
1.3
—
—
—
0
0
54
754
0.70
1.82
4.1
4.3
32.45
30.96
%
0.53
42
539
175
1463
1.25
1.82
2.5
2.1
2.99
3.02
mg/l
0.06
149
1255
34
215
1.61
1.82
2.4
3.0
—
—
—
0
0
78
585
1.37
1.81
2.7
2.3
0.20
0.22
g/l
1.58
72
548
334
2986
1.20
1.79
3.1
2.6
—
—
—
0
0
29
178
1.65
1.75
1.9
1.8
—
—
—
0
0
45
307
1.49
1.74
1.9
1.9
—
—
—
0
0
25
148
1.71
1.72
1.4
1.2
366.65
278.19
u/ml
0.78
20
93
23
136
1.71
1.60
2.0
1.7
—
—
—
0
0
55
399
1.41
1.57
6.1
3.4
1.59
1.59
mmol/l
0.00
39
302
121
987
1.26
1.56
3.3
3.0
2.44
2.44
mmol/l
0.06
102
876
219
1905
1.20
1.55
4.3
3.9
18.47
9.44
mg/mmol
0.99
147
1245
16
86
1.88
1.51
1.2
1.7
—
—
—
0
0
16
86
1.88
1.51
1.2
1.7
—
—
—
0
0
22
131
1.70
1.50
3.2
2.5
15.73
16.54
%
0.29
13
69
37
251
1.50
1.50
1.6
1.3
29.36
26.11
iu/l
0.15
31
213
12
58
2.08
1.49
1.2
1.2
—
—
—
0
0
576
6052
0.84
1.49
6.8
5.4
40.97
39.73
mmol/mol
1.89
538
5686
598
6262
0.84
1.49
18.6
11.9
88.14
84.91
ml/min/173m2
3.07
509
5176
95
758
1.29
1.47
4.1
2.8
14.39
7.99
umol/l
0.63
84
675
219
1915
1.20
1.46
3.7
3.4
2.34
2.35
mmol/l
0.21
200
1716
18
102
1.78
1.45
1.4
1.7
—
—
—
0
0
268
2393
1.18
1.40
4.5
3.4
43.95
42.40
ng/l
0.05
188
1619
275
2462
1.18
1.39
4.1
3.3
—
—
—
0
0
60
453
1.35
1.38
2.9
3.1
175.25
185.98
ng/l
0.09
52
407
189
1643
1.20
1.34
3.1
3.1
1234.97
1220.02
ng/l
0.02
157
1397
336
3067
1.16
1.31
7.0
6.0
57.33
56.94
%
0.25
323
2901
340
3115
1.16
1.25
7.2
6.3
28.07
28.00
%
0.04
328
2946
686
7066
0.83
1.23
13.1
10.0
31.55
29.27
u/l
1.44
672
6866
165
1429
1.19
1.22
1.7
1.9
1.11
1.12
mg/l
0.00
126
1085
5
19
2.64
1.21
1.4
1.9
—
—
—
0
0
24
156
1.55
1.21
1.5
1.2
—
—
—
0
0
6
26
2.32
1.19
1.5
1.7
280.78
54.17
ug/l
—
6
26
8
38
2.12
1.18
1.6
2.2
—
350.17
—
0
6
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
21
134
1.58
1.15
2.4
2.2
128.88
131.70
g/l
0.18
16
107
19
119
1.61
1.12
1.3
1.7
—
—
—
0
0
19
119
1.61
1.12
1.3
1.7
—
—
—
0
0
19
120
1.60
1.09
3.1
1.7
—
—
—
0
0
8
41
1.96
1.09
3.3
3.0
35490.25
39229.39
ug/l
—
8
41
28
194
1.46
1.08
1.4
1.4
217.86
289.28
ug/g
0.78
14
114
493
4667
1.14
1.07
5.2
3.2
67.68
51.82
u/l
1.82
473
4418
6
122
0.49
1.06
2.7
4.4
136.83
375.79
u/ml
—
6
117
496
4701
1.14
1.05
3.9
3.6
14.66
14.64
pmol/l
0.07
460
4300
9
47
1.92
1.02
2.8
1.4
18.27
19.79
nmol/l
—
9
42
195
1740
1.16
1.01
2.6
2.7
358.70
5106.67
umol/l
4.92
171
1556
25
172
1.47
1.01
1.5
1.8
—
—
—
0
0
7
36
1.95
0.97
1.3
1.1
223.57
96.53
u/l
—
7
36
7
36
1.95
0.97
1.3
1.1
102.14
29.38
u/l
—
7
36
89
745
1.22
0.96
10.4
6.4
—
—
—
0
0
0
31
0.00
0.96
0.0
2.3
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
8.70
—
0
32
20
138
1.46
0.82
1.5
1.6
—
—
—
0
0
87
1015
0.84
0.81
1.2
1.3
7.51
13.89
u/ml
0.56
31
428
11
66
1.68
0.79
1.5
1.6
—
—
—
0
0
11
66
1.68
0.79
1.5
1.6
—
—
—
0
0
11
66
1.68
0.79
1.5
1.6
—
—
—
0
0
284
2645
1.11
0.75
3.1
2.7
114.51
139.35
ug/l
1.31
263
2463
12
76
1.59
0.72
1.3
1.5
—
—
—
0
0
23
169
1.37
0.70
1.6
1.8
—
—
—
0
0
61
512
1.21
0.68
3.0
2.5
67.38
71.50
ml/min/173m2
0.39
29
198
5
28
1.79
0.66
1.0
1.2
—
—
—
0
0
11
70
1.58
0.65
5.0
3.6
—
—
—
0
0
30
233
1.30
0.65
3.4
3.6
710.99
4909.76
u/ml
0.49
25
199
93
815
1.16
0.65
2.0
2.0
—
—
—
0
0
19
138
1.39
0.63
1.4
1.4
—
—
—
0
0
29
228
1.28
0.59
1.3
1.3
10.77
7.38
u/l
0.40
24
187
84
737
1.16
0.59
1.9
1.9
—
—
—
0
0
126
1137
1.13
0.59
1.6
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
2.0
—
—
—
0
0
20
149
1.35
0.58
1.7
1.6
27226.07
13589.29
e6/l
0.36
15
112
6
35
1.72
0.57
1.3
1.5
—
—
—
0
0
19
141
1.36
0.56
1.4
1.3
7.68
10.47
e6/l
0.14
19
109
19
141
1.36
0.56
1.5
1.4
1263.53
1439.50
e6/l
0.04
19
113
17
124
1.38
0.56
1.6
1.9
—
—
—
0
0
25
317
0.78
0.55
1.7
1.8
35.64
36.74
nmol/l
0.10
25
306
9
63
1.43
0.52
1.1
1.1
—
—
—
0
0
6
40
1.50
0.51
1.2
1.0
—
—
—
0
0
23
180
1.29
0.50
7.0
3.2
1.92
1.48
mg/l
1.25
23
166
7
110
0.63
0.48
1.4
1.5
—
—
—
0
0
13
177
0.73
0.47
1.2
1.4
—
—
—
0
0
11
78
1.42
0.43
1.3
1.9
—
—
—
0
0
14
184
0.76
0.42
1.3
1.3
—
—
—
0
0
97
1063
0.90
0.42
1.3
1.3
22.54
31.74
iu/ml
0.76
33
351
18
228
0.78
0.41
1.7
2.4
17.07
44.72
u/ml
1.46
18
215
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
66
588
1.13
0.41
2.4
2.1
382.44
364.99
nmol/l
0.25
55
544
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
14
106
1.33
0.39
1.7
1.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
32.64
—
0
19
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
22
268
0.82
0.37
1.6
1.6
—
—
—
0
0
11
147
0.74
0.37
1.2
1.2
—
—
—
0
0
8
115
0.69
0.37
1.0
1.1
—
10.93
—
0
9
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
18
143
1.26
0.37
1.3
1.2
3.93
3.81
mmol/l
0.15
18
134
6
42
1.43
0.35
2.0
1.9
—
—
—
0
0
20
163
1.23
0.34
1.5
1.4
—
—
—
0
0
20
164
1.22
0.33
1.4
1.2
491.10
502.40
mg/l
0.05
20
154
46
408
1.13
0.32
1.4
1.2
119.78
147.08
iu/ml
0.14
19
160
666
6571
1.07
0.31
21.3
13.5
27.11
23.83
mg/l
1.71
569
5181
39
343
1.14
0.31
1.3
1.3
—
—
—
0
0
478
4674
1.05
0.30
3.6
3.9
11.72
10.77
mm/h
0.72
442
4355
15
120
1.25
0.30
1.3
1.1
—
—
—
0
0
7
56
1.25
0.29
2.0
1.9
—
—
—
0
0
27
313
0.86
0.29
1.1
1.0
—
—
—
0
0
8
62
1.29
0.28
1.3
1.8
—
—
—
0
0
17
204
0.83
0.27
1.1
2.5
—
—
—
0
0
68
738
0.91
0.27
2.4
2.3
13.02
13.30
nmol/l
0.11
62
673
11
86
1.28
0.26
1.4
1.8
—
—
—
0
0
5
74
0.67
0.26
2.0
1.5
236.28
164.43
pmol/l
—
5
74
12
149
0.80
0.26
1.6
1.4
—
—
—
0
0
435
4433
0.96
0.22
3.2
3.0
—
—
—
0
0
5
41
1.22
0.22
2.2
1.9
—
—
—
0
0
5
42
1.19
0.21
1.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
77.57
—
0
10
5
43
1.16
0.21
1.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
19.79
—
0
8
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.5
—
8.70
—
0
7
679
6729
1.05
0.20
24.8
15.0
139.29
139.67
mmol/l
3.08
669
6559
20
174
1.15
0.20
2.6
2.2
453.94
81.69
ug/min
—
10
103
144
1382
1.05
0.19
1.4
1.2
1.51
1.67
u/ml
0.11
37
407
7
58
1.21
0.18
2.1
2.6
—
—
—
0
0
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
24
268
0.89
0.17
6.3
3.9
24.70
24.87
mmol/l
0.12
24
256
10
120
0.83
0.16
1.2
1.6
—
—
—
0
0
8
70
1.14
0.16
1.0
1.0
—
—
—
0
0
16
183
0.87
0.16
1.0
1.1
—
—
—
0
0
8
71
1.13
0.16
1.4
1.2
—
—
—
0
0
13
111
1.17
0.16
2.5
1.5
—
—
—
0
0
6
76
0.79
0.15
1.0
1.1
—
—
—
0
0
9
79
1.14
0.15
1.4
1.1
—
—
—
0
0
18
202
0.89
0.14
1.3
2.0
—
—
—
0
0
577
5824
0.97
0.14
4.8
4.2
1.82
2.08
mu/l
0.65
533
5371
8
96
0.83
0.13
1.0
1.1
—
—
—
0
0
15
134
1.12
0.11
4.3
3.6
60.67
56.54
%
0.78
15
134
679
6755
1.03
0.10
24.7
15.1
3.97
3.98
mmol/l
0.24
667
6581
5
47
1.06
0.09
2.2
1.8
—
—
—
0
0
56
584
0.96
0.09
4.0
4.6
4.72
32.75
ug/l
1.25
47
485
11
124
0.89
0.09
1.3
1.2
—
1.02
—
0
9
573
5767
0.98
0.09
26.2
15.8
14.64
14.73
%
0.16
568
5677
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
13
117
1.11
0.08
1.2
1.1
—
—
—
0
0
10
88
1.14
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.1
1.2
—
—
—
0
0
6
70
0.86
0.07
1.2
3.1
6.95
79.36
nmol/l
—
6
70
8
74
1.08
0.07
1.1
1.1
—
—
—
0
0
8
77
1.04
0.07
2.0
2.0
—
—
—
0
0
12
132
0.91
0.06
1.3
1.2
—
—
—
0
0
14
151
0.93
0.05
1.6
1.6
—
—
—
0
0
14
151
0.93
0.05
1.4
1.5
—
—
—
0
0
23
218
1.06
0.05
1.3
1.6
2.01
0.07
iu/ml
—
5
36
14
130
1.08
0.04
3.6
3.1
5.28
4.21
e9/l
0.54
14
130
23
241
0.95
0.04
2.2
1.9
—
—
—
0
0
173
1745
0.99
0.03
1.7
1.7
1.62
1.45
mmol/l
1.42
149
1503
13
123
1.06
0.01
1.0
1.1
2.86
2.89
u/ml
—
6
67
13
123
1.06
0.01
1.1
1.2
—
48.31
—
0
8
15
143
1.05
0.01
1.7
2.0
2.64
5.21
iu/l
—
5
48
14
134
1.05
0.00
1.6
1.5
—
—
—
0
0
14
134
1.05
0.00
1.6
1.5
—
—
—
0
0
14
134
1.05
0.00
1.6
1.5
—
—
—
0
0
14
134
1.05
0.00
1.6
1.5
—
—
—
0
0
22
226
0.97
0.00
2.0
1.8
—
—
—
0
0
26
254
1.02
0.00
1.9
2.0
—
—
—
0
0
14
137
1.02
0.00
1.6
1.6
—
—
—
0
0
17
173
0.98
0.00
1.4
1.5
—
—
—
0
0
19
188
1.01
0.00
1.4
1.5
—
—
—
0
0
11
111
0.99
0.00
2.0
2.0
14.09
13.20
%
0.58
11
111
76
761
1.00
0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
1.45
—
0
6
0
6
0.00
0.00
0.0
5.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
8.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
94.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.6
69.60
79.05
umol/l
—
5
58
8
80
1.00
-0.00
2.1
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.54
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
1.1
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
78
0.90
-0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
397.40
—
0
5
78
780
1.00
-0.00
2.4
2.4
179.68
129.06
ug/g
0.27
65
643
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ST19_TOXIC_EFFECT_ALCOHOL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_TOXIC_EFFECT_ALCOHOL | 4.993 [3.52, 7.08] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 999 females with ST19_TOXIC_EFFECT_ALCOHOL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_TOXIC_EFFECT_ALCOHOL | 5.096 [4.25, 6.11] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 587 out of 2166 males with ST19_TOXIC_EFFECT_ALCOHOL died.
Mortality risk
Mortality risk for people of age
years, who have ST19_TOXIC_EFFECT_ALCOHOL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.512% | 0.933% |
| 5 | 2.421% | 5.27% |
| 10 | 6.017% | 13.689% |
| 15 | 11.05% | 24.353% |
| 20 | 18.141% | 38.048% |
Relationships between endpoints
↥Index endpoint: ST19_TOXIC_EFFECT_ALCOHOL – Toxic effect of alcohol
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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