No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
726 |
4. Check minimum number of eventsNone |
726 |
5. Include endpointsNone |
726 |
6. Filter based on genotype QC (FinnGen only) |
690 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q6[5-9]|Q7
- Name in latin
- Deformitates congenitae coxae
Similar endpoints
↥List of similar endpoints to
Congenital deformities of hip
based on the number of shared cases.
Similar with more cases:
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17520 | 12354 | 5155 |
| Only index persons | 11084 | 7907 | 3177 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.29 | 0.35 | 0.14 |
| Only index persons | 0.24 | 0.29 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 0.08 | 0.05 | 0.06 |
| Only index persons | 0.13 | 0.10 | 0.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 690 | 562 | 128 |
| Unadjusted period prevalence (%) | 0.17 | 0.20 | 0.06 |
| Median age at first event (years) | 25.85 | 27.01 | 20.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 726
- Matched controls
- 7255
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
+∞
285.8
255
*
NF1AA
NOMESCO Finland
Hip X-ray examination
16.9
203.3
188
147
NFF25
NOMESCO Finland
Cleaning of hip joint, arthroscopic
82.2
138.5
74
10
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
410.0
136.6
133
*
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
122.4
114
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
25.5
117.3
84
37
M16.1
ICD-10 Finland
Other primary coxarthrosis
10.2
115.8
145
174
Q65.88
ICD-10 Finland
Other congenital deformities of hip
+∞
115.8
108
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
10.9
112.1
131
143
Q65.80
ICD-10 Finland
Congenital dysplastic hip or acetabulum, unilateral
+∞
110.3
103
*
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
13.6
106.1
105
89
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
+∞
105.8
99
*
L13
ICPC
Hip symptom/complaint
5.9
100.5
229
522
Q65.81
ICD-10 Finland
Congenital dysplastic hip or acetabulum, bilateral
+∞
98.2
92
*
NF1DA
NOMESCO Finland
X-ray of hips
20.8
81.4
63
33
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
10.5
71.7
83
88
Q65.3
ICD-10 Finland
Congenital subluxation of hip, unilateral
+∞
64.5
61
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
78.9
58.1
65
9
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
23.4
57.4
42
19
NFG00
NOMESCO Finland
Arthroplasty of hip joint
310.1
57.1
57
*
NFE15
NOMESCO Finland
Plastic repair of capsule or ligament of hip joint
591.4
56.4
55
*
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
125.8
54.7
58
5
M16.2
ICD-10 Finland
Coxarthrosis resulting from dysplasia, bilateral
556.4
53.2
52
*
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
7.3
52.8
82
124
7543A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Congenital dislocation of hip[LUXATIO COXAE CONGENITA]
510.3
49.0
48
*
Q65.6
ICD-10 Finland
Unstable hip
+∞
47.4
45
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
11.9
47.1
49
44
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.9
40.4
57
77
Q65.2
ICD-10 Finland
Congenital dislocation of hip, unspecified
+∞
35.7
34
*
75560
ICD-8 Finland
Other congenital anomalies of limbs, Dislocatio congenita coxae (fixata)
363.8
35.3
35
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.7
32.0
38
41
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
86.3
30.0
33
*
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
35.3
29.0
37
11
NEK99
NOMESCO Finland
Other operation on bone of pelvis
107.7
28.9
31
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
11.5
28.6
30
27
N02AX02
ATC
tramadol; systemic, rectal
2.5
28.6
262
1341
B01AB05
ATC
enoxaparin; parenteral
2.7
27.8
200
910
ZXA00
NOMESCO Finland
Right side
2.7
26.7
177
772
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
7.4
26.5
39
55
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
26.9
26.4
36
14
N03AX16
ATC
[U] pregabalin
2.8
25.9
159
666
L89
ICPC
Osteoarthrosis of hip
8.2
25.3
34
43
ZXA05
NOMESCO Finland
Left side
2.7
24.1
161
702
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
129.2
23.7
25
*
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
8.5
23.6
31
38
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
5.5
23.2
46
88
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
37.6
23.1
29
8
Q65.9
ICD-10 Finland
Congenital deformity of hip, unspecified
+∞
23.0
22
*
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
64.6
22.0
25
*
L28
ICPC
Limited function/disability (L)
2.9
21.6
115
443
9165
FHL
Removal of osteosynthesis material
9.3
21.3
26
29
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
17.5
20.6
32
19
B01AF01
ATC
rivaroxaban; oral
3.5
19.8
71
216
NFC00
NOMESCO Finland
Exchange of a loose part of prosthesis in hip joint
107.9
19.7
21
*
WX130
NOMESCO Finland
Interpleural anesthesia
102.7
18.6
20
*
M25.5
ICD-10 Finland
Pain in joint
2.1
17.8
259
1544
75561
ICD-8 Finland
Other congenital anomalies of limbs, Praeluxatio congenita coxae (non fixata, fenomeno Ortolani positivo)
97.4
17.6
19
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
17.4
243
1426
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
13.1
16.8
29
23
NEU20
NOMESCO Finland
Removal of internal fixation device from pelvis
+∞
16.7
16
*
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
28.3
16.6
22
8
A28
ICPC
Limited function/disability NOS
2.8
16.5
90
350
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
16.3
71
243
R4110
NOMESCO Finland
Physiotherapy
2.1
16.1
204
1150
M01AH01
ATC
celecoxib; oral
2.6
16.0
103
435
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
16.0
101
423
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
5.6
15.8
30
55
7152E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,LONKKANIVEL]
61.4
15.8
18
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
15.8
199
1118
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
15.8
54
159
R5110, ,
SPAT
3.9
15.1
45
120
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
5.8
14.7
27
48
B01AX06
ATC
[U] rivaroxaban
12.2
14.7
26
22
S70.0
ICD-10 Finland
Contusion of hip
4.5
14.6
36
83
Q65.4
ICD-10 Finland
Congenital subluxation of hip, bilateral
+∞
14.6
14
*
Q65.82
ICD-10 Finland
Congenital anterversion of the collum femoris
+∞
14.6
14
*
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
14.6
14
*
9402
FHL
Plastering in the operating room and possible repositioning
+∞
14.6
14
*
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
10.7
14.3
27
26
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
14.0
160
862
WX320
NOMESCO Finland
Spinalanesthesy
2.2
14.0
141
724
NFA30
NOMESCO Finland
Exploration of hip joint, arthroscopic
50.9
12.9
15
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
12.7
96
436
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
12.7
277
1847
9321
FHL
The first reartroplast due to detachment, also includes the treatment of a fracture due to detachment
+∞
12.5
12
*
Q65.5
ICD-10 Finland
Congenital subluxation of hip, unspecified
+∞
12.5
12
*
M91.2
ICD-10 Finland
Coxa plana
+∞
12.5
12
*
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
14.6
12.3
20
14
M76.0
ICD-10 Finland
Gluteal tendinitis
5.2
12.3
25
49
SPAT1216
SPAT
Assessment of functional ability
2.4
12.2
91
411
M01AH05
ATC
etoricoxib; oral
1.7
11.9
360
2624
M76.1
ICD-10 Finland
Psoas tendinitis
30.6
11.7
15
5
N02AA05
ATC
oxycodone; systemic
2.5
11.5
76
324
TNF31
NOMESCO Finland
Prefabricated orthosis, hip or thigh
+∞
11.5
11
*
9964A
ICD-9 Finland
Complications peculiar to certain specified procedures, Mechanical complication of internal orthopaedic device, implant and graft
+∞
11.5
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
11.4
65
258
A02BC05
ATC
esomeprazole; systemic
1.8
11.4
219
1396
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
11.4
163
946
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.7
11.2
26
57
71300
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) coxae
44.0
10.9
13
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
44.0
10.9
13
*
S73.1
ICD-10 Finland
Sprain and strain of hip
15.8
10.9
17
11
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
14.5
10.5
17
12
Q65.8
ICD-10 Finland
Other congenital deformities of hip
+∞
10.4
10
*
NF1AA, ,
SPAT
3.8
10.3
32
88
SPAT1229
SPAT
Assessment of need for aid
3.3
10.3
39
123
M01AH02
ATC
rofecoxib; oral
2.6
10.1
58
231
Z50.1
ICD-10 Finland
Other physical therapy
3.4
9.8
36
111
M79.6
ICD-10 Finland
Pain in limb
1.7
9.7
276
1948
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.3
9.5
78
366
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.1
9.4
90
450
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.4
342
2562
NFC99
NOMESCO Finland
Other secondary prosthetic replacement in hip joint, other or unspecified
+∞
9.4
9
*
L29
ICPC
Musculoskeletal sympt/complt other
2.4
9.4
68
303
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
8.4
9.1
19
23
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
9.1
56
231
N03AX12
ATC
[U] gabapentin; oral
2.1
8.9
89
452
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.1
8.9
38
129
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
8.8
47
180
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.7
346
2635
A02BC02
ATC
pantoprazole; systemic
1.6
8.5
354
2718
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
4.2
8.5
22
53
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
27.9
8.5
11
*
9403
FHL
Adductorotomy
+∞
8.3
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
8.3
180
1174
WX402
NOMESCO Finland
General anaesthesia
1.7
8.2
159
1004
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
8.1
224
1553
J01FF01
ATC
clindamycin; systemic
1.8
8.0
149
931
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
8.0
60
272
L08
ICPC
Shoulder symptom/complaint
1.8
8.0
124
734
N02BE01
ATC
paracetamol; systemic, rectal
1.7
7.9
561
4852
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
7.8
62
288
N02BF02
ATC
pregabalin; oral
2.7
7.6
40
153
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.8
7.4
37
137
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.8
7.4
36
132
SPAT1153
SPAT
Removal of sutures
1.7
7.4
159
1032
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.4
232
1656
Q65.83
ICD-10 Finland
Congenital coxa whale
+∞
7.3
7
*
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
7.3
7
*
Q65
ICD-10 Finland
Congenital deformities of hip
+∞
7.3
7
*
WX002
NOMESCO Finland
Sedation and analgesia
1.8
7.3
107
621
M01AE02
ATC
naproxen; oral, rectal
1.5
7.2
437
3595
NFH30
NOMESCO Finland
Reduction of dislocation prosthesis of hip joint, closed
15.9
7.2
11
7
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.7
7.2
39
151
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
7.2
115
685
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
30.3
7.2
9
*
M05BA04
ATC
alendronic acid; oral
2.9
7.1
33
118
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.0
149
962
M41.9
ICD-10 Finland
Scoliosis, unspecified
4.4
7.0
17
39
M01AB55
ATC
diclofenac, combinations; oral
3.0
7.0
31
108
M01AX17
ATC
nimesulide; oral
1.9
6.9
94
532
S18
ICPC
Laceration/cut
1.5
6.9
264
1965
Z3226
NOMESCO Finland
Physiotherapist
1.7
6.7
131
826
N02CC05
ATC
almotriptan; oral
2.7
6.6
36
140
M01AH03
ATC
valdecoxib; oral
2.9
6.5
29
101
B01AB04
ATC
dalteparin; parenteral
3.0
6.5
28
96
NF2AT, ,
SPAT
70.4
6.4
7
*
R5130, ,
SPAT
70.4
6.4
7
*
M16.5
ICD-10 Finland
Other post-traumatic coxarthrosis
70.4
6.4
7
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
6.4
29
102
M22.0
ICD-10 Finland
Recurrent dislocation of patella
3.4
6.3
22
66
R00.2
ICD-10 Finland
Palpitations
2.1
6.3
61
307
9322
FHL
Subsequent reartroplast due to detachment also includes treatment of the fracture due to detachment
+∞
6.3
6
*
NF1CB
NOMESCO Finland
Hip artrography with X-ray
+∞
6.3
6
*
9406
FHL
Pelvic osteotomy
+∞
6.3
6
*
NFK70
NOMESCO Finland
Bone transport operation of femur
+∞
6.3
6
*
9341
FHL
Reduction and plaster or plaster exchange
+∞
6.3
6
*
R52.2
ICD-10 Finland
Other chronic pain
3.0
6.2
27
93
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.2
115
715
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
6.1
44
196
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
6.0
75
412
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
3.5
6.0
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
348
2528
1.72
11.48
3.3
2.6
—
—
—
0
0
203
1289
1.80
10.58
3.0
2.4
—
—
—
0
0
392
2990
1.67
10.40
5.4
5.2
6.07
6.18
mmol/l
0.57
362
2715
329
2437
1.64
9.50
9.1
8.0
1.22
1.22
mmol/l
1.08
292
2138
255
1775
1.67
9.37
6.9
7.9
1.05
1.09
inr
0.78
77
559
499
4133
1.66
8.93
4.4
3.8
10.19
9.06
mm/h
1.09
465
3830
300
2241
1.58
7.95
8.9
8.2
1.22
1.22
mmol/l
0.97
278
2078
91
488
1.99
7.86
3.1
3.3
32.14
32.60
%
0.15
70
344
264
1935
1.57
7.49
5.3
5.2
37.17
37.05
g/l
0.15
243
1824
71
369
2.02
6.69
9.3
9.0
0.11
0.89
mmol/l
0.87
59
291
316
2462
1.50
6.54
7.5
5.9
11.30
13.85
umol/l
1.47
288
2296
70
369
1.99
6.35
9.3
9.0
5.14
5.26
kpa
0.51
64
357
205
1479
1.54
6.01
2.5
2.4
55.95
59.55
u/l
0.44
184
1373
448
3790
1.47
5.88
4.6
4.0
277.88
408.34
e6/l
—
8
47
99
623
1.68
5.07
3.2
2.5
23.78
22.19
%
0.41
90
553
613
5603
1.60
4.99
15.5
11.4
139.51
139.57
mmol/l
0.29
600
5439
112
733
1.62
4.93
9.7
8.3
1.18
1.22
mmol/l
0.65
104
691
446
3835
1.42
4.92
8.4
6.1
81.77
84.28
u/l
0.51
428
3613
30
126
2.44
4.78
2.6
2.2
258.54
186.72
ug/l
0.41
24
112
63
354
1.85
4.76
6.0
5.6
60.63
61.61
ng/l
0.05
57
331
28
115
2.49
4.68
1.3
1.2
—
—
—
0
0
373
3129
1.39
4.63
7.4
6.5
31.53
31.96
%
0.31
347
2982
612
5616
1.57
4.63
15.7
11.4
3.93
3.92
mmol/l
0.64
596
5431
644
5996
1.65
4.40
14.6
10.5
18.84
20.61
mg/l
0.89
505
4444
112
753
1.58
4.40
3.0
2.4
14.05
14.06
umol/l
0.01
102
706
8
9
8.97
4.28
1.0
1.3
—
—
—
0
0
45
235
1.97
4.25
2.0
1.7
—
—
—
0
0
27
115
2.40
4.20
4.6
4.4
1.45
1.62
%
0.27
22
106
287
2336
1.38
4.14
3.1
2.5
73.90
72.36
nmol/l
0.42
258
2151
529
4754
1.41
4.10
4.4
3.8
14.57
14.43
pmol/l
0.69
483
4333
364
3085
1.36
4.03
7.2
6.3
53.49
53.74
%
0.15
339
2935
203
1566
1.41
4.01
3.5
2.8
2.35
2.37
mmol/l
1.47
178
1414
73
453
1.68
3.96
10.0
10.6
6.40
6.16
mmol/l
0.19
67
439
103
696
1.56
3.96
3.1
2.4
2.49
2.52
g/l
0.24
95
646
529
4766
1.40
3.94
11.2
8.6
98.30
95.73
ml/min/173m2
1.53
435
3633
120
841
1.51
3.91
3.8
3.9
827.98
961.73
ng/l
0.25
98
689
54
310
1.80
3.85
1.8
1.6
—
—
—
0
0
94
632
1.56
3.70
1.6
1.6
1003.25
1144.01
nmol/l
0.87
69
489
187
1442
1.40
3.67
2.4
2.4
2.65
2.75
mg/l
0.33
164
1250
9
16
5.68
3.66
1.1
2.0
126.23
128.54
ug/l
—
9
16
76
487
1.62
3.65
6.8
7.6
106.28
105.03
mmol/l
1.74
76
487
21
86
2.48
3.57
1.6
1.5
—
—
—
0
0
404
3525
1.33
3.48
9.8
8.8
3.89
3.81
e9/l
0.30
347
3044
87
583
1.56
3.48
8.1
10.0
1.25
1.08
mmol/l
0.20
66
413
182
1409
1.39
3.47
2.9
2.8
117.68
23.19
ng/l
0.50
86
681
163
1242
1.40
3.41
2.6
2.1
206.03
226.43
u/l
0.12
149
1180
132
970
1.44
3.38
1.4
1.4
19.44
20.53
nmol/l
0.36
113
841
18
71
2.57
3.31
1.7
1.3
—
—
—
0
0
18
73
2.50
3.14
1.7
1.3
—
—
—
0
0
18
73
2.50
3.14
1.7
1.3
—
—
—
0
0
106
758
1.47
3.13
6.5
6.5
0.81
0.81
mmol/l
0.20
101
718
144
1090
1.40
3.12
2.3
2.5
95.79
97.02
ug/g
0.02
112
850
211
1703
1.34
3.04
1.8
1.7
99.19
97.66
pmol/l
0.18
111
889
127
949
1.41
2.96
1.3
1.2
23.46
8.85
u/ml
0.67
43
361
100
717
1.46
2.91
2.2
1.9
—
—
—
0
0
216
1762
1.32
2.87
3.5
3.4
33.06
30.46
u/l
0.22
205
1692
30
158
1.94
2.84
1.4
1.2
2.12
11.64
u/ml
—
5
27
584
5445
1.37
2.83
5.1
4.5
1.87
2.06
mu/l
0.42
546
5102
17
71
2.43
2.81
1.7
1.3
—
—
—
0
0
119
887
1.41
2.81
3.4
2.9
3.42
3.85
e6/l
0.21
61
480
17
72
2.39
2.74
1.7
1.3
—
—
—
0
0
17
72
2.39
2.74
1.7
1.3
—
—
—
0
0
186
1498
1.32
2.69
3.4
3.2
0.35
0.30
e6/l
0.14
136
1112
220
1815
1.30
2.67
1.6
1.5
1.81
1.85
g/l
0.16
134
1048
31
170
1.86
2.62
1.4
1.2
—
19.84
—
0
12
221
1831
1.30
2.59
4.1
3.4
—
—
—
0
0
126
966
1.37
2.52
1.3
1.2
39.56
26.73
iu/ml
0.27
36
295
33
188
1.79
2.49
2.9
1.9
—
—
—
0
0
87
634
1.42
2.35
6.8
8.0
1.06
1.29
mmol/l
0.33
76
496
118
911
1.35
2.26
3.2
2.8
1.08
1.11
e6/l
0.05
62
500
147
1176
1.31
2.21
2.3
2.5
1.35
1.11
mg/l
0.26
106
847
239
2036
1.26
2.19
1.5
1.5
1.26
2.63
u/ml
1.05
59
484
30
174
1.75
2.16
2.3
1.9
—
—
—
0
0
197
1643
1.27
2.15
3.7
3.3
25.37
50.62
e6/l
0.96
151
1239
63
441
1.47
2.11
1.8
1.7
22.95
20.75
iu/l
0.20
52
341
455
4170
1.24
2.11
4.2
4.2
36.96
37.65
mmol/mol
0.84
425
3922
404
3665
1.23
2.03
3.5
3.1
34.60
32.62
u/l
0.24
386
3497
8
26
3.10
2.01
1.3
1.1
—
—
—
0
0
324
2875
1.23
2.01
3.7
3.2
0.00
0.01
estimate
0.50
74
556
94
716
1.36
1.97
3.1
2.3
2.42
2.43
mmol/l
0.38
81
624
19
98
1.96
1.96
1.2
1.2
—
—
—
0
0
22
120
1.86
1.94
1.7
1.3
—
—
—
0
0
320
2848
1.22
1.90
5.2
4.5
0.00
0.00
estimate
0.50
73
577
136
1100
1.29
1.88
2.6
2.8
10.02
8.72
e6/l
0.33
121
981
13
59
2.22
1.84
1.4
1.2
—
—
—
0
0
6
17
3.55
1.84
1.0
1.4
—
—
—
0
0
27
160
1.71
1.84
1.4
1.5
0.30
0.33
nmol/l
0.14
27
133
510
4768
1.23
1.81
3.6
3.3
5.59
5.58
mmol/l
0.06
463
4407
199
1704
1.23
1.69
2.5
2.4
—
—
—
0
0
318
2853
1.20
1.68
3.7
3.2
0.00
0.00
estimate
-0.00
73
585
12
56
2.16
1.61
6.7
1.7
—
—
—
0
0
6
20
3.01
1.58
1.8
1.3
—
—
—
0
0
6
20
3.01
1.58
1.8
1.3
—
—
—
0
0
13
64
2.05
1.54
1.1
1.1
—
—
—
0
0
20
115
1.76
1.53
3.4
1.7
0.60
3.70
ug/l
0.74
14
107
343
3121
1.19
1.50
3.4
2.9
84.26
61.42
ug/l
1.99
324
2932
13
65
2.02
1.49
1.1
1.1
—
—
—
0
0
16
87
1.86
1.46
2.1
2.8
837.55
504.03
e6/l
1.54
11
66
5
16
3.14
1.44
1.4
5.9
—
—
—
0
0
9
39
2.32
1.43
3.2
1.4
—
—
—
0
0
21
127
1.67
1.37
1.3
1.5
30.47
17.30
u/l
0.68
16
109
208
1824
1.20
1.37
2.6
2.5
—
—
—
0
0
53
393
1.38
1.36
3.7
3.1
4.88
4.74
pmol/l
0.39
46
345
24
151
1.61
1.36
1.2
1.3
328.33
336.43
ug/g
—
9
80
5
17
2.95
1.36
2.0
1.3
—
—
—
0
0
5
17
2.95
1.36
1.0
2.9
229.00
216.47
u/l
—
5
17
5
17
2.95
1.36
2.0
1.3
—
—
—
0
0
22
343
0.63
1.34
1.5
1.6
—
—
—
0
0
38
267
1.45
1.32
1.2
1.3
—
—
—
0
0
14
76
1.86
1.30
1.4
1.2
—
—
—
0
0
77
961
0.78
1.30
3.9
3.9
4.94
28.63
mg/mmol
0.71
49
618
8
34
2.37
1.29
1.0
1.6
—
—
—
0
0
5
18
2.79
1.28
6.0
6.1
—
—
—
0
0
5
18
2.79
1.28
5.8
5.9
—
—
—
0
0
8
35
2.30
1.27
1.0
1.1
114.69
143.10
iu/ml
—
8
35
35
245
1.45
1.25
1.5
1.7
—
—
—
0
0
8
36
2.23
1.24
2.5
2.1
—
—
—
0
0
18
286
0.62
1.20
1.3
1.5
—
—
—
0
0
63
491
1.31
1.20
2.0
2.3
39.96
31.93
u/l
0.39
47
404
11
57
1.94
1.17
2.5
4.3
—
3.42
—
0
7
5
20
2.51
1.15
4.8
1.6
—
—
—
0
0
5
20
2.51
1.15
4.8
1.6
—
—
—
0
0
142
1222
1.20
1.15
1.8
1.7
1.29
1.35
mmol/l
0.41
130
1075
19
119
1.61
1.12
4.0
3.5
24.64
22.55
mg/l
0.14
11
78
73
586
1.27
1.12
1.1
1.1
—
—
—
0
0
10
51
1.97
1.11
1.1
1.2
—
—
—
0
0
10
51
1.97
1.11
1.1
1.2
—
—
—
0
0
10
51
1.97
1.11
1.1
1.2
—
—
—
0
0
10
51
1.97
1.11
1.1
1.2
—
—
—
0
0
63
497
1.29
1.11
1.9
1.8
—
—
—
0
0
23
338
0.67
1.10
1.9
2.0
—
—
—
0
0
5
21
2.39
1.09
4.8
1.6
—
—
—
0
0
25
169
1.50
1.08
3.0
2.7
51.87
3.80
e6/l
0.68
15
127
113
958
1.21
1.07
3.2
2.9
302.81
5551.24
umol/l
3.92
97
869
92
764
1.23
1.06
3.3
3.2
181.85
533.09
ng/l
1.85
55
458
26
178
1.48
1.06
1.7
2.8
360.12
419.45
mg/l
0.39
26
170
10
52
1.93
1.06
1.1
1.2
—
—
—
0
0
25
170
1.49
1.05
3.1
2.8
2530.12
296.23
e6/l
0.58
17
134
62
492
1.28
1.05
5.2
4.7
—
—
—
0
0
15
90
1.68
1.04
2.2
2.3
18.74
16.93
%
—
9
48
240
2175
1.15
1.03
3.8
3.1
—
—
—
0
0
20
298
0.66
1.03
1.4
1.7
—
—
—
0
0
37
273
1.37
1.02
1.2
1.1
—
—
—
0
0
44
571
0.76
1.02
1.5
1.5
—
—
—
0
0
40
300
1.35
1.01
1.7
1.6
—
—
—
0
0
693
6811
1.37
0.98
21.2
15.5
4.48
4.53
e12/l
1.87
681
6600
9
50
1.81
0.97
1.1
1.1
—
—
—
0
0
12
69
1.75
0.96
1.1
1.1
—
—
—
0
0
54
674
0.78
0.95
1.4
1.5
—
—
—
0
0
14
85
1.66
0.94
1.4
1.3
—
—
—
0
0
6
27
2.23
0.93
1.7
2.2
29.37
16.39
umol/l
—
6
27
692
6804
1.35
0.93
21.2
15.6
262.54
266.44
e9/l
0.87
678
6608
62
502
1.26
0.92
2.0
1.9
—
—
—
0
0
6
28
2.15
0.91
4.2
1.5
—
—
—
0
0
6
28
2.15
0.91
2.5
1.6
—
—
—
0
0
6
28
2.15
0.91
4.2
1.5
—
—
—
0
0
693
6817
1.35
0.91
21.4
15.7
132.12
133.57
g/l
2.15
685
6730
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
110
1.56
0.91
3.8
12.9
0.20
0.34
u/ml
—
10
72
32
236
1.37
0.91
1.6
1.8
242.74
191.80
u/ml
0.37
19
115
28
202
1.40
0.90
1.9
1.8
—
—
—
0
0
13
79
1.66
0.88
1.7
1.9
13.31
13.16
%
0.20
13
79
11
64
1.73
0.86
1.1
1.7
—
—
—
0
0
32
239
1.35
0.85
2.2
2.3
15.84
5.42
ug/l
0.62
22
212
21
146
1.45
0.83
1.4
1.4
—
—
—
0
0
21
146
1.45
0.83
1.4
1.4
—
—
—
0
0
22
155
1.43
0.81
1.8
1.8
5.22
5.91
iu/l
—
9
55
8
47
1.71
0.81
1.6
1.2
—
—
—
0
0
18
122
1.49
0.80
3.1
1.9
—
—
—
0
0
615
5991
1.17
0.79
11.2
8.4
23.97
24.69
u/l
0.50
592
5802
8
48
1.67
0.79
1.8
2.2
105.75
105.77
mmol/l
—
8
48
15
100
1.51
0.73
1.0
1.1
—
—
—
0
0
5
25
2.01
0.72
1.2
1.1
—
—
—
0
0
5
25
2.01
0.72
1.2
1.2
—
—
—
0
0
5
25
2.01
0.72
1.2
1.2
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
5
26
1.93
0.70
4.2
5.7
—
—
—
0
0
35
275
1.29
0.69
1.2
1.2
1.80
7.42
u/ml
3.20
22
182
690
6804
1.27
0.69
21.7
15.8
39.44
39.79
%
1.09
666
6473
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
7
42
1.67
0.68
3.7
1.5
—
—
—
0
0
7
42
1.67
0.68
3.7
1.5
—
—
—
0
0
7
42
1.67
0.68
1.6
1.1
—
83.75
—
0
8
7
42
1.67
0.68
3.7
1.5
—
—
—
0
0
73
624
1.19
0.68
3.4
4.2
5.04
6.53
umol/l
0.90
58
520
12
78
1.55
0.65
2.2
3.2
—
—
—
0
0
60
506
1.20
0.65
2.1
1.9
—
—
—
0
0
19
138
1.39
0.63
4.3
8.7
25.24
23.76
mmol/l
0.76
19
132
5
30
1.67
0.61
1.2
1.5
—
—
—
0
0
26
200
1.31
0.61
3.7
7.1
0.70
0.65
%
0.24
26
200
166
1520
1.12
0.61
3.9
3.3
0.00
0.01
estimate
1.08
73
563
19
139
1.38
0.60
1.6
1.4
—
—
—
0
0
37
299
1.25
0.60
1.2
1.2
0.82
3.27
u/ml
2.26
22
189
94
831
1.15
0.59
1.4
1.5
457.69
37397699.50
pmol/l
1.31
81
730
14
97
1.45
0.59
8.6
5.3
439.14
392.77
umol/l
0.55
14
88
37
301
1.24
0.57
3.8
3.7
2.16
1.62
ug/l
0.55
32
270
8
55
1.46
0.56
1.1
1.1
—
—
—
0
0
21
159
1.33
0.55
1.0
1.1
—
—
—
0
0
33
267
1.25
0.54
1.2
1.2
0.30
1.43
u/ml
1.50
19
158
40
333
1.21
0.52
1.5
2.5
92.00
78.33
ml/min/173m2
—
8
129
120
1314
0.90
0.50
1.5
1.4
—
—
—
0
0
17
127
1.35
0.49
2.3
3.9
36.00
33.99
umol/l
0.23
12
111
209
2222
0.92
0.49
1.9
1.9
—
—
—
0
0
78
694
1.14
0.47
2.1
2.2
1682.63
5885.30
u/l
1.83
21
250
10
68
1.48
0.47
1.0
1.1
—
—
—
0
0
7
48
1.46
0.47
2.3
5.0
2.39
2.21
ug/l
—
7
48
17
129
1.32
0.46
2.4
1.9
—
—
—
0
0
17
129
1.32
0.46
2.4
1.9
—
—
—
0
0
33
274
1.21
0.45
1.3
1.5
—
—
—
0
0
21
165
1.28
0.45
1.0
1.1
0.15
0.56
u/ml
1.37
11
66
36
302
1.20
0.45
5.6
3.9
2.72
7.01
ug/l
1.70
28
236
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
51
1.38
0.44
1.3
1.2
—
—
—
0
0
9
127
0.70
0.43
3.8
3.6
3.45
4.01
e9/l
—
9
127
9
130
0.69
0.43
4.3
3.8
47.44
55.25
%
—
9
130
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
495
4824
1.08
0.42
3.9
3.7
2.83
2.79
mmol/l
0.35
465
4530
6
95
0.63
0.42
1.5
1.1
—
—
—
0
0
23
185
1.25
0.42
2.5
3.5
7.61
10.60
umol/l
0.38
17
147
22
176
1.26
0.42
1.1
1.1
12.73
10.79
u/ml
0.15
12
79
8
58
1.38
0.41
1.4
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
339.25
—
0
12
12
88
1.37
0.40
3.0
3.5
478.07
52.89
u/ml
0.42
12
88
8
61
1.31
0.39
1.1
1.1
124.00
183.86
mg/l
—
8
55
30
251
1.20
0.39
1.4
1.4
—
—
—
0
0
20
160
1.26
0.38
2.1
1.9
—
—
—
0
0
39
336
1.17
0.38
2.2
1.8
7.05
9.50
u/l
0.74
31
241
9
68
1.33
0.37
1.1
1.1
—
—
—
0
0
491
4795
1.07
0.37
3.7
3.5
4.66
4.67
mmol/l
0.02
461
4532
5
77
0.65
0.36
1.2
1.1
—
—
—
0
0
31
362
0.85
0.35
1.4
1.5
—
—
—
0
0
17
135
1.26
0.35
1.2
1.2
—
—
—
0
0
47
415
1.14
0.34
2.9
2.7
—
—
—
0
0
21
253
0.82
0.33
1.3
1.3
—
—
—
0
0
557
5476
1.07
0.31
17.9
13.3
14.33
13.98
%
0.94
545
5394
7
55
1.27
0.30
1.3
1.6
—
—
—
0
0
33
288
1.15
0.29
1.5
1.3
—
—
—
0
0
90
835
1.09
0.29
1.5
1.5
1.38
1.36
%
0.13
81
770
114
1213
0.93
0.29
2.4
2.1
—
—
—
0
0
14
112
1.25
0.28
1.4
2.4
10.19
10.00
mg/l
0.03
14
105
464
4546
1.06
0.27
3.4
3.2
1.16
1.20
mmol/l
0.50
428
4261
24
205
1.18
0.27
1.7
2.1
44.00
39.22
u/l
0.51
24
189
8
65
1.23
0.27
1.1
1.4
—
—
—
0
0
23
196
1.18
0.27
1.4
1.5
—
—
—
0
0
30
263
1.15
0.26
1.2
1.1
2.30
3.17
u/ml
0.26
18
167
9
75
1.20
0.25
1.6
1.5
—
—
—
0
0
134
1407
0.94
0.24
3.5
3.4
8.06
8.04
mmol/l
0.01
120
1252
29
327
0.88
0.23
1.4
1.4
—
—
—
0
0
29
327
0.88
0.23
1.4
1.4
—
—
—
0
0
13
106
1.23
0.23
1.2
1.5
—
—
—
0
0
30
266
1.13
0.22
2.2
1.8
11.87
9.80
nmol/l
0.42
25
242
29
326
0.88
0.22
1.3
1.4
—
—
—
0
0
29
326
0.88
0.22
1.3
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
21
183
1.15
0.20
1.9
1.8
—
—
—
0
0
29
260
1.12
0.19
5.4
5.7
2.77
3.07
g/l
0.81
29
251
6
52
1.15
0.19
1.2
1.7
—
—
—
0
0
61
570
1.08
0.18
1.5
1.4
328.12
287.01
u/ml
0.14
53
529
12
142
0.84
0.17
1.2
1.1
1.24
4.90
u/ml
—
5
61
18
157
1.15
0.17
2.7
2.0
—
—
—
0
0
32
291
1.10
0.17
1.4
1.8
4.39
3.46
mg/l
0.34
22
204
7
63
1.11
0.17
1.6
1.4
—
—
—
0
0
13
151
0.86
0.16
1.4
1.2
—
—
—
0
0
9
80
1.13
0.15
1.4
1.5
—
—
—
0
0
97
1011
0.95
0.15
2.3
2.0
—
—
—
0
0
9
81
1.11
0.15
1.7
1.7
—
—
—
0
0
481
4755
1.03
0.14
3.7
3.4
1.48
1.50
mmol/l
0.38
449
4473
532
5364
0.97
0.13
4.0
3.9
—
—
—
0
0
21
191
1.10
0.11
1.1
1.2
—
—
—
0
0
137
1336
1.03
0.10
3.8
3.1
1.01
1.02
kg/l
0.41
24
203
5
47
1.06
0.09
2.0
1.4
—
—
—
0
0
13
117
1.11
0.08
2.5
1.9
—
—
—
0
0
21
195
1.08
0.08
1.1
1.2
—
—
—
0
0
6
72
0.83
0.07
1.3
1.1
—
—
—
0
0
26
245
1.06
0.07
4.5
3.2
20.57
22.93
%
0.36
12
91
9
86
1.05
0.07
2.2
2.2
—
—
—
0
0
24
227
1.06
0.05
2.0
1.5
—
—
—
0
0
46
445
1.04
0.05
1.4
1.4
—
—
—
0
0
10
110
0.91
0.05
1.2
1.9
—
—
—
0
0
39
376
1.04
0.05
1.4
1.3
334.68
258.93
miu/ml
0.52
19
191
15
140
1.07
0.04
1.5
1.5
—
—
—
0
0
21
200
1.05
0.03
1.1
1.1
16.25
8.04
u/ml
0.54
11
107
11
102
1.08
0.03
1.4
2.0
—
—
—
0
0
11
102
1.08
0.03
1.4
2.0
—
—
—
0
0
55
559
0.98
0.02
1.3
1.3
—
—
—
0
0
25
243
1.03
0.01
1.6
1.5
1.14
1.19
g/l
0.34
25
228
10
94
1.06
0.00
1.3
1.9
—
—
—
0
0
10
98
1.02
0.00
1.1
1.2
2.00
3.23
u/ml
—
5
39
60
597
1.00
0.00
1.3
1.3
169.44
148.40
iu/ml
0.14
18
229
10
102
0.98
0.00
1.2
1.8
—
—
—
0
0
24
235
1.02
0.00
1.7
1.5
0.21
0.23
g/l
0.47
24
223
14
138
1.01
0.00
14.2
7.3
493.00
355.53
iu/ml
—
5
19
12
125
0.96
0.00
1.3
1.2
—
—
—
0
0
5
49
1.02
0.00
1.2
1.3
7.48
8.57
u/ml
—
5
39
0
7
0.00
-0.00
0.0
1.1
—
213.71
—
0
7
9
90
1.00
-0.00
3.3
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
24.20
—
0
6
7
69
1.01
-0.00
3.9
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
-0.00
1.0
1.3
0.33
0.52
nmol/l
—
6
62
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
0.67
—
0
6
6
63
0.95
-0.00
1.2
1.7
—
—
—
0
0
8
83
0.96
-0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
-0.00
1.1
1.1
—
—
—
0
0
6
63
0.95
-0.00
1.5
3.8
26.00
27.25
umol/l
—
6
63
6
65
0.92
-0.00
2.3
2.1
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.2
11.89
15.20
u/ml
—
5
42
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_DEFORMITI_HIP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_DEFORMITI_HIP | 1.38 [1.15, 1.65] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.083 |
During the follow-up period (1.1.1998 — 31.12.2019), 242 out of 11663 females with Q17_CONGEN_DEFORMITI_HIP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_DEFORMITI_HIP | 1.696 [1.33, 2.16] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 4808 males with Q17_CONGEN_DEFORMITI_HIP died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_DEFORMITI_HIP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.388% |
| 5 | 0.763% | 2.236% |
| 10 | 1.75% | 5.465% |
| 15 | 3.518% | 10.243% |
| 20 | 6.237% | 17.495% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_DEFORMITI_HIP – Congenital deformities of hip
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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