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Sequelae of transport accidents

VWXY20_SEQUEL_TRANSPO_ACCIDENTS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Y85
  • Cause of death: ICD-10 Y85

2 out of 7 registries used, show all original rules.

169

4. Check minimum number of events

None

169

5. Include endpoints

None

169

6. Filter based on genotype QC (FinnGen only)

169

Control definitions (FinnGen only)

Control exclude
VWXY20_SEQUEL_EXTER_CAUSES_MORBIDI_MORTA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Y8[5-9]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 169 73 96
Unadjusted period prevalence (%) 0.03 0.02 0.04
Median age at first event (years) 48.03 40.75 53.56

-FinnGen-

Age distribution of first events

0102030405060708002468101214161820222426AgeIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520002005201020152020202305101520253035404550YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
147
Matched controls
1470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Y85.0
ICD-10 Finland
Sequelae of motor-vehicle accident
+∞
148.0
116
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
169.1
37.7
38
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
25.3
35.7
51
30
Y85.9
ICD-10 Finland
Sequelae of other and unspecified transport accidents
+∞
34.8
32
*
S06.2
ICD-10 Finland
Diffuse brain injury
54.0
19.8
23
5
X59
ICD-10 Finland
Exposure to unspecified factor
5.1
15.0
55
154
V49.2
ICD-10 Finland
Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident
51.2
12.1
14
*
V29.9
ICD-10 Finland
Motorcycle rider [any] injured in unspecified traffic accident
25.4
11.8
16
7
S06.0
ICD-10 Finland
Concussion
5.3
11.0
35
81
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
64.8
10.8
12
*
V48.9
ICD-10 Finland
Car occupant injured in noncollision transport accident, unspecified car occupant injured in traffic accident
32.4
9.6
12
*
XA800
NOMESCO Finland
Neuropsychological investigation
10.1
9.3
18
20
M03BX01
ATC
baclofen; systemic
20.2
9.1
13
7
S02.40
ICD-10 Finland
Fracture of malar and maxillary bones, closed
25.9
9.1
12
5
S06.3
ICD-10 Finland
Focal brain injury
21.6
8.6
12
6
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.0
8.4
35
106
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.9
7.7
21
40
L89
ICD-10 Finland
Decubitus ulcer and pressure area
26.6
7.7
10
*
V03.1
ICD-10 Finland
Pedestrian injured in collision with car, pick-up truck or van, traffic accident
84.1
7.5
8
*
T91.1
ICD-10 Finland
Sequelae of fracture of spine
+∞
7.3
7
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.2
7.3
22
48
W19
ICD-10 Finland
Unspecified fall
4.4
7.3
26
68
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
8.2
7.1
15
20
X58
ICD-10 Finland
Exposure to other specified factors
3.3
6.9
37
135
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
6.9
56
270
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.5
6.9
24
61
N03AE01
ATC
clonazepam; systemic
6.1
6.9
18
33
N03AX16
ATC
pregabalin; oral
3.1
6.9
42
170
S42.0
ICD-10 Finland
Fracture of clavicle
8.0
6.6
14
19
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
72.8
6.5
7
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
72.8
6.5
7
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
72.8
6.5
7
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
9.9
6.4
12
13
V48.2
ICD-10 Finland
Car occupant injured in noncollision transport accident, person on outside of vehicle injured in nontraffic accident
+∞
6.3
6
*
N81
ICPC
Injury nervous system other
+∞
6.3
6
*
ZZA00
NOMESCO Finland
Split skin graft
8.3
6.3
13
17
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.5
6.2
21
52

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
327
2.12
4.77
5.7
4.3
—
—
—
0
0
46
263
2.03
3.79
4.6
2.3
4.69
4.52
e6/l
0.04
41
231
29
139
2.31
3.70
2.3
1.6
—
—
—
0
0
7
9
8.05
3.59
1.7
1.2
—
—
—
0
0
66
455
1.74
2.95
7.7
7.7
1.15
1.19
inr
0.18
17
137
54
352
1.78
2.92
2.4
2.1
163.48
456.47
u/l
0.89
54
336
59
395
1.76
2.92
2.7
2.3
—
—
—
0
0
16
66
2.57
2.80
3.2
1.6
—
—
—
0
0
57
383
1.74
2.76
4.5
2.7
11.32
63.42
e6/l
1.91
46
294
64
446
1.70
2.71
5.1
3.2
30.42
40.29
e6/l
0.26
49
306
17
74
2.44
2.68
3.1
1.6
—
—
—
0
0
51
341
1.71
2.48
4.1
2.6
—
—
—
0
0
33
202
1.79
2.16
3.3
3.0
47.23
695.80
ng/l
0.73
22
141
50
344
1.64
2.16
3.9
2.8
7.25
8.35
mmol/l
0.78
44
298
50
344
1.64
2.16
4.4
2.6
0.01
0.41
e6/l
2.90
38
258
17
82
2.19
2.15
3.1
1.5
—
—
—
0
0
17
83
2.17
2.09
3.1
1.5
—
—
—
0
0
5
10
5.11
2.08
1.4
1.2
—
—
—
0
0
15
70
2.25
2.05
3.1
3.0
128.80
138.55
ng/l
0.06
15
64
17
84
2.14
2.04
3.2
1.5
—
—
—
0
0
34
504
0.59
1.98
3.0
2.4
—
—
—
0
0
53
386
1.54
1.78
3.2
2.6
48.17
55.31
u/l
1.09
48
361
48
342
1.56
1.77
7.6
2.7
—
—
—
0
0
68
523
1.50
1.77
7.2
6.4
1.20
1.21
mmol/l
0.25
63
480
13
61
2.23
1.76
5.3
1.7
—
—
—
0
0
7
24
3.00
1.74
3.4
3.5
63.86
55.42
%
—
7
24
7
24
3.00
1.74
2.9
3.5
4.56
4.14
e9/l
—
7
24
11
49
2.33
1.67
4.0
1.6
—
—
—
0
0
16
84
2.00
1.66
1.9
1.5
—
—
—
0
0
72
568
1.47
1.62
7.3
6.8
1.21
1.21
mmol/l
0.18
63
485
73
579
1.46
1.60
6.4
5.7
0.78
0.67
%
1.11
66
550
81
657
1.45
1.57
4.7
5.9
9.81
11.54
umol/l
0.93
70
620
64
498
1.46
1.53
4.8
4.5
35.43
36.31
g/l
0.49
59
472
27
173
1.67
1.52
3.4
2.2
—
—
—
0
0
75
603
1.44
1.51
6.5
5.5
2.75
2.75
%
0.00
69
572
75
604
1.43
1.49
6.6
5.9
8.38
8.46
%
0.08
69
580
5
16
3.19
1.45
3.4
1.6
—
—
—
0
0
14
74
1.97
1.44
5.9
3.3
—
7.43
—
0
8
54
413
1.45
1.40
4.7
5.3
—
—
—
0
0
76
621
1.41
1.37
6.5
5.5
28.52
28.47
%
0.01
69
596
59
461
1.43
1.36
3.7
3.8
44.23
43.28
ng/l
0.02
35
292
42
308
1.48
1.34
5.2
7.0
—
—
—
0
0
78
642
1.40
1.34
6.3
5.5
0.56
0.58
e9/l
0.32
67
569
78
645
1.39
1.29
6.3
5.5
0.04
0.04
e9/l
0.40
67
571
11
57
1.99
1.20
5.8
3.6
—
—
—
0
0
17
104
1.71
1.14
8.1
7.6
1.47
1.33
mmol/l
0.19
17
99
79
666
1.35
1.12
6.5
5.6
1.85
1.99
e9/l
0.51
70
596
79
668
1.34
1.09
6.4
5.9
0.19
0.19
e9/l
0.15
69
592
144
1517
0.66
1.05
27.6
18.3
136.31
138.30
g/l
0.84
144
1498
144
1517
0.66
1.05
27.5
18.3
6.92
6.75
e9/l
0.45
144
1484
21
140
1.57
1.03
6.0
24.5
1.16
1.19
inr
—
5
14
95
830
1.33
1.03
8.7
4.0
25.60
243.88
e6/l
—
5
16
144
1516
0.66
1.02
27.5
18.2
4.52
4.59
e12/l
0.91
144
1485
144
1516
0.66
1.02
27.4
18.1
30.33
30.27
pg
0.16
144
1497
144
1516
0.66
1.02
27.4
18.2
90.81
90.46
fl
0.38
144
1498
9
49
1.88
1.00
1.6
1.2
—
—
—
0
0
38
291
1.39
0.96
2.3
2.0
2.53
2.96
mg/l
0.73
32
255
144
1513
0.67
0.95
27.6
18.3
259.27
248.59
e9/l
1.01
144
1484
16
104
1.59
0.88
3.2
4.5
—
—
—
0
0
72
616
1.29
0.87
6.4
5.3
57.05
56.81
%
0.05
65
590
10
165
0.58
0.87
1.0
1.3
—
—
—
0
0
12
188
0.61
0.86
1.3
1.4
—
—
—
0
0
9
151
0.57
0.83
1.7
1.3
—
—
—
0
0
8
47
1.74
0.82
1.8
1.6
—
—
—
0
0
33
255
1.37
0.80
4.2
2.6
520.77
565.64
mosm/kgh2o
0.42
26
222
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
19
133
1.48
0.77
1.2
1.5
—
—
—
0
0
25
186
1.40
0.75
3.3
3.4
0.82
0.82
mmol/l
0.06
25
173
28
360
0.73
0.75
7.3
2.9
—
—
—
0
0
106
964
1.27
0.75
4.4
3.6
14.34
14.68
pmol/l
0.73
101
873
20
143
1.45
0.74
13.3
10.8
3.42
0.97
mmol/l
1.77
15
111
56
473
1.28
0.73
1.9
1.9
—
—
—
0
0
67
580
1.26
0.71
9.0
8.7
0.00
0.00
e9/l
0.30
55
465
18
127
1.47
0.71
1.3
1.3
—
—
—
0
0
21
153
1.43
0.71
1.5
1.5
—
—
—
0
0
5
26
1.95
0.71
5.6
1.8
—
—
—
0
0
11
69
1.64
0.70
5.2
5.6
26.99
24.68
mmol/l
1.14
11
69
7
44
1.62
0.66
1.3
1.2
—
—
—
0
0
25
191
1.36
0.66
2.0
2.3
1.02
1.93
e6/l
0.61
15
96
111
1191
0.80
0.64
24.5
15.9
333.75
334.16
g/l
0.17
111
1183
12
79
1.56
0.64
3.6
3.0
84.56
72.06
ng/l
0.57
12
72
54
461
1.25
0.64
1.9
1.8
85.87
93.27
pmol/l
0.60
33
239
40
329
1.28
0.64
4.0
3.7
—
—
—
0
0
5
29
1.75
0.64
1.4
1.3
—
—
—
0
0
8
49
1.66
0.63
1.4
1.1
—
—
—
0
0
8
50
1.63
0.62
1.3
1.2
—
—
—
0
0
0
22
0.00
0.60
0.0
1.6
—
—
—
0
0
39
324
1.26
0.58
1.4
1.3
2.59
1.02
u/ml
—
8
84
8
54
1.51
0.58
1.4
1.3
—
—
—
0
0
84
759
1.21
0.58
9.0
9.4
4.05
4.14
e9/l
0.15
71
666
36
297
1.27
0.57
3.4
3.1
1114.51
101.96
mg/l
0.44
28
200
35
288
1.27
0.56
1.8
1.6
0.58
1.07
mg/l
2.22
25
213
106
984
1.21
0.53
7.6
7.0
81.81
75.79
u/l
0.41
100
924
10
67
1.52
0.51
3.0
2.1
—
—
—
0
0
12
84
1.46
0.51
11.2
9.7
—
—
—
0
0
35
293
1.25
0.49
5.1
3.5
1.01
1.02
kg/l
—
8
23
11
77
1.46
0.47
3.1
2.8
685.66
2136.72
u/l
—
5
32
120
1262
0.83
0.47
19.9
13.4
40.67
40.87
%
0.12
91
1007
35
298
1.22
0.43
1.5
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
137
1418
0.82
0.40
17.4
11.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
66
1.38
0.39
21.2
15.6
—
—
—
0
0
13
98
1.35
0.39
2.7
5.7
5.29
9.29
mmol/l
3.81
13
92
9
70
1.30
0.37
1.2
1.2
—
—
—
0
0
118
1230
0.87
0.33
4.6
4.1
5.83
5.86
mmol/l
0.10
108
1135
6
46
1.32
0.33
1.7
1.4
—
—
—
0
0
16
128
1.28
0.33
1.2
1.1
—
—
—
0
0
36
319
1.16
0.29
4.0
3.8
5.48
14.32
mg/mmol
1.27
26
211
35
310
1.16
0.29
5.1
4.2
—
—
—
0
0
25
215
1.19
0.29
1.2
1.3
22.82
24.92
iu/ml
—
10
66
19
159
1.22
0.28
1.1
1.4
—
—
—
0
0
93
883
1.12
0.27
7.3
3.8
—
—
—
0
0
5
73
0.68
0.26
1.4
1.8
—
—
—
0
0
27
306
0.86
0.25
1.4
1.4
2.51
2.47
g/l
0.05
14
198
6
85
0.70
0.24
1.5
1.6
1.10
1.08
g/l
—
6
80
5
37
1.36
0.24
1.2
1.2
—
—
—
0
0
13
107
1.23
0.22
2.1
2.6
0.18
0.23
g/l
1.24
13
99
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
11.03
—
0
11
0
11
0.00
0.21
0.0
1.1
—
253.68
—
0
11
0
10
0.00
0.21
0.0
1.8
—
33.30
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
3.6
—
69.04
—
0
13
23
203
1.15
0.20
3.5
2.2
60.31
121.66
ug/g
1.56
16
163
6
49
1.23
0.20
2.2
1.6
21.00
21.90
s
—
6
42
98
943
1.09
0.19
4.5
3.5
9.87
9.39
mm/h
0.13
86
876
12
101
1.20
0.17
5.7
3.5
0.60
0.97
%
—
5
31
39
363
1.10
0.15
2.1
2.0
—
—
—
0
0
7
88
0.79
0.15
1.4
1.3
—
—
—
0
0
9
108
0.82
0.13
4.4
3.1
—
—
—
0
0
11
127
0.86
0.13
1.5
1.4
—
—
—
0
0
43
409
1.07
0.10
1.6
1.5
—
—
—
0
0
5
43
1.17
0.10
12.4
5.1
—
—
—
0
0
31
292
1.08
0.09
5.3
3.3
—
—
—
0
0
134
1321
1.07
0.09
21.0
14.2
139.06
139.63
mmol/l
1.51
134
1285
134
1322
1.07
0.08
20.8
14.2
3.94
3.95
mmol/l
0.21
134
1285
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
8
73
1.10
0.07
1.5
1.1
—
—
—
0
0
59
572
1.05
0.07
3.6
2.5
134.46
111.04
ug/l
0.22
54
539
9
85
1.06
0.07
2.4
2.2
—
16.67
—
0
6
11
99
1.12
0.06
13.5
8.5
—
—
—
0
0
133
1344
0.95
0.06
22.5
12.6
23.56
23.83
mg/l
0.04
111
1021
51
496
1.04
0.05
5.6
3.2
—
—
—
0
0
10
110
0.90
0.05
13.7
3.0
—
—
—
0
0
63
641
0.97
0.03
6.1
3.4
0.00
0.00
estimate
0.00
11
122
62
630
0.97
0.02
8.0
4.6
0.00
0.00
estimate
0.00
11
128
11
103
1.07
0.02
2.7
3.2
—
—
—
0
0
35
357
0.98
0.01
6.9
3.4
0.00
0.00
estimate
0.00
11
123
15
149
1.01
0.00
1.4
1.9
—
—
—
0
0
22
219
1.01
0.00
1.4
1.5
—
—
—
0
0
63
628
1.01
0.00
6.0
3.3
0.00
0.00
estimate
—
10
131
115
1155
0.99
0.00
5.2
5.1
39.60
39.17
mmol/mol
0.16
110
1089
15
155
0.96
0.00
2.2
2.6
7.62
9.45
umol/l
—
8
131
21
212
0.99
0.00
1.7
1.7
—
—
—
0
0
85
849
1.00
0.00
3.4
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
118
1180
1.00
0.00
5.4
4.2
1.76
1.87
mu/l
0.57
112
1089
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
0.00
5.1
4.0
4.51
4.54
pmol/l
—
7
67
0
5
0.00
0.00
0.0
1.6
—
0.21
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
6
63
0.95
0.00
1.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
1.77
—
0
6
0
5
0.00
0.00
0.0
4.0
—
12.80
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
9.20
—
0
5
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
32.40
—
0
5
0
6
0.00
0.00
0.0
1.3
—
28.67
—
0
6
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
50.60
—
0
5
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_SEQUEL_TRANSPO_ACCIDENTS – Sequelae of transport accidents

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).