No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1322 |
4. Check minimum number of eventsNone |
1322 |
5. Include endpointsNone |
1322 |
6. Filter based on genotype QC (FinnGen only) |
1322 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Bicuspidal aortic valve syndrome
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of aortic and mitral valves
- Left ventricular outflow tract obstruction, narrow definition
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1322 | 420 | 902 |
| Unadjusted period prevalence (%) | 0.32 | 0.14 | 0.40 |
| Median age at first event (years) | 54.13 | 51.83 | 55.20 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
893
2556
8.68
307.65
4.0
3.1
804.7
1207.9
ng/l
2.43
829
2161
570
1588
5.55
200.84
4.0
2.5
30.5
29.9
s
1.55
558
1544
413
874
6.42
197.15
2.5
2.3
18.3
7.4
ug/l
10.37
402
791
460
1152
5.59
181.10
52.2
19.9
2.2
1.3
inr
6.34
29
181
892
4014
4.76
161.94
29.2
8.3
2.0
1.2
inr
48.18
285
1179
316
699
5.63
140.17
3.1
2.8
166.7
175.6
ng/l
0.15
296
624
461
1887
3.22
82.83
4.9
3.6
2072.4
560.0
ng/l
6.58
423
1417
323
1121
3.49
75.24
3.5
4.6
282.8
245.9
u/l
3.52
310
1068
57
30
19.81
73.09
11.1
6.8
—
—
—
0
0
584
2998
2.70
66.05
2.6
2.2
366.9
301.0
u/l
0.61
558
2830
795
4798
2.65
63.79
4.4
4.0
—
—
—
0
0
495
2477
2.60
57.22
2.4
2.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
133
317
4.55
51.83
9.4
3.2
0.3
0.3
u/ml
0.23
85
172
910
6206
2.50
51.14
8.7
5.4
6.6
6.7
mmol/l
1.26
880
5822
264
1017
2.99
49.91
8.0
9.2
7.8
9.0
mmol/l
2.48
256
972
366
1699
2.60
48.13
4.5
4.5
0.8
0.8
mmol/l
2.48
353
1616
629
3756
2.29
46.59
3.8
3.4
84.7
60.8
ng/l
0.61
450
2546
258
1086
2.71
40.67
17.1
9.8
97.8
96.0
%
13.89
252
1048
271
1191
2.60
39.05
16.7
9.3
5.2
5.1
kpa
0.76
264
1148
271
1191
2.60
39.05
16.6
9.2
14.1
12.6
kpa
3.72
263
1151
784
5371
2.13
38.34
6.1
6.8
15.2
12.3
umol/l
5.48
750
5126
269
1193
2.58
37.95
16.7
9.3
1.1
1.0
mmol/l
0.15
234
949
1281
11069
6.07
36.34
24.5
15.2
139.3
139.7
mmol/l
6.56
1268
10801
1283
11110
6.25
36.06
24.2
15.2
4.0
4.0
mmol/l
3.76
1270
10824
202
822
2.72
33.63
3.4
2.5
60.6
70.6
ml/min/173m2
2.54
71
311
181
698
2.85
33.38
15.7
11.4
95.8
94.3
%
10.38
181
692
457
2691
2.07
32.08
5.3
4.4
74.5
90.0
%
20.23
452
2637
301
1558
2.21
29.18
2.5
2.6
13.4
13.9
umol/l
0.42
288
1459
162
649
2.71
27.58
20.0
8.0
25.0
24.5
mmol/l
1.18
155
607
235
1122
2.33
27.52
3.1
3.4
1.6
1.7
%
0.75
224
1021
156
618
2.73
27.13
5.3
4.2
120.4
131.2
g/l
6.56
150
604
64
149
4.46
25.51
10.3
6.7
10.7
10.7
mg/l
0.00
57
138
1240
10914
3.20
24.97
18.8
13.3
35.0
24.1
mg/l
19.52
1089
8467
274
1451
2.12
24.65
2.5
2.6
2.4
2.3
g/l
0.52
263
1360
261
1359
2.15
24.52
2.6
2.7
23.4
24.2
%
0.27
231
1181
640
4503
1.82
24.49
11.2
7.1
1.2
1.2
mmol/l
20.01
605
4128
683
4926
1.80
23.83
11.1
7.8
1.2
1.2
mmol/l
18.21
599
4230
145
593
2.62
23.58
23.8
12.8
—
—
—
0
0
1285
11686
4.56
21.89
22.7
15.1
80.7
78.8
umol/l
1.21
1285
11681
1164
10080
2.29
21.67
16.5
12.0
84.9
85.7
ml/min/173m2
0.60
1034
8260
983
8072
1.85
20.60
7.5
7.7
76.1
80.9
u/l
3.12
947
7651
526
3642
1.74
20.06
3.5
3.6
35.2
38.7
u/l
0.32
508
3469
275
1581
1.93
19.22
1.8
1.9
—
—
—
0
0
371
2425
1.74
16.77
2.4
2.3
3.2
2.9
mg/l
1.31
340
2082
67
216
3.21
16.77
1.4
1.7
—
—
—
0
0
201
1099
1.98
16.06
1.8
1.8
—
—
—
0
0
103
430
2.51
15.97
2.0
2.0
1.3
1.5
g/l
0.92
68
373
345
2272
1.70
14.92
3.0
2.0
1.2
1.1
mg/l
0.32
245
1710
189
1041
1.95
14.73
4.1
5.3
2.0
1.9
mmol/l
0.28
157
835
99
422
2.45
14.68
3.3
2.0
1.9
2.3
ug/l
0.19
90
384
198
1117
1.91
14.35
1.8
1.8
—
—
—
0
0
80
323
2.57
13.30
1.5
1.7
—
—
—
0
0
1064
9354
1.70
13.03
23.7
16.1
13.6
13.5
%
0.13
1052
9164
567
4325
1.54
12.98
3.0
2.8
226.5
146.0
ug/l
0.42
534
4029
1307
12409
5.69
12.95
28.9
19.2
233.7
247.2
e9/l
13.51
1286
12097
565
4308
1.54
12.95
5.6
5.5
35.7
36.1
g/l
0.74
533
4040
916
7776
1.58
12.77
4.0
3.9
10.8
10.5
mm/h
0.27
866
7231
1307
12418
5.63
12.74
28.9
19.2
4.4
4.6
e12/l
28.31
1283
12074
1307
12421
5.60
12.67
28.9
19.3
6.8
6.7
e9/l
1.69
1284
12074
1307
12421
5.60
12.67
29.2
19.3
132.6
139.5
g/l
40.63
1296
12264
1080
9563
1.71
12.51
4.5
4.2
1.9
2.1
mu/l
0.57
1004
8791
206
1228
1.80
12.44
9.5
6.6
—
—
—
0
0
147
786
1.98
12.42
15.0
10.9
25.1
24.9
mmol/l
0.35
147
780
1254
11711
2.38
11.42
11.5
10.1
28.7
29.7
u/l
1.03
1219
11368
49
178
2.82
10.05
1.4
1.3
5.3
3.7
u/ml
0.18
24
65
895
7754
1.48
9.69
3.8
3.5
14.9
14.7
pmol/l
1.20
821
7081
1137
10390
1.67
9.54
4.4
3.9
1.3
1.4
mmol/l
1.02
1084
9648
94
471
2.07
9.50
2.8
4.0
0.7
0.7
%
0.71
94
459
47
174
2.76
9.32
1.3
1.2
6.8
6.0
u/ml
0.11
30
81
62
268
2.38
8.98
1.5
1.9
—
—
—
0
0
61
262
2.39
8.96
1.5
1.9
—
—
—
0
0
109
590
1.92
8.87
1.6
1.6
—
—
—
0
0
378
2850
1.46
8.27
3.4
3.1
0.4
0.4
e6/l
0.35
294
2131
35
118
3.02
8.23
3.0
2.4
32.8
33.1
pg
0.18
35
118
1165
10818
1.65
7.90
4.9
4.3
4.5
4.6
mmol/l
6.36
1118
10139
471
3732
1.41
7.73
3.5
3.3
—
—
—
0
0
735
6274
1.39
7.71
9.2
9.8
4.1
4.1
e9/l
0.20
657
5471
109
619
1.83
7.66
5.4
6.1
24.2
24.1
mmol/l
0.27
102
574
1174
10939
1.65
7.65
5.4
4.6
2.7
2.8
mmol/l
4.50
1127
10185
1121
10339
1.55
7.55
4.2
4.2
5.9
6.0
mmol/l
0.75
1042
9526
1126
10406
1.55
7.40
22.0
14.0
39.8
41.0
%
6.64
875
7988
1157
10765
1.60
7.31
4.8
4.2
1.4
1.4
mmol/l
0.41
1108
10028
288
2109
1.47
7.20
2.7
2.5
3.9
4.8
e6/l
0.49
247
1860
1073
9833
1.48
7.17
5.1
5.4
38.2
39.6
mmol/mol
5.70
1017
9216
99
585
1.75
6.13
1.4
1.4
—
—
—
0
0
43
190
2.31
6.01
1.3
1.7
—
—
—
0
0
38
160
2.42
5.92
1.4
1.8
—
—
—
0
0
38
161
2.40
5.84
1.3
1.6
—
—
—
0
0
729
6385
1.32
5.62
4.0
3.9
42.0
1497.9
e6/l
—
9
92
238
1782
1.41
5.15
3.0
2.9
0.7
0.9
e6/l
1.27
153
1011
33
140
2.39
5.09
1.3
1.6
—
—
—
0
0
31
129
2.44
4.99
1.4
2.0
—
—
—
0
0
42
205
2.08
4.67
2.6
4.4
—
2341.6
—
0
19
40
192
2.12
4.65
1.4
2.0
—
—
—
0
0
18
59
3.08
4.52
1.3
1.2
—
—
—
0
0
42
208
2.05
4.51
1.4
1.3
—
—
—
0
0
42
208
2.05
4.51
1.4
1.3
—
—
—
0
0
837
7612
1.27
4.20
2.9
3.1
—
—
—
0
0
391
3266
1.28
3.94
2.9
2.7
62.2
56.9
u/l
0.79
360
3054
61
360
1.73
3.88
1.4
1.8
—
—
—
0
0
32
152
2.13
3.86
1.2
1.7
—
—
—
0
0
27
120
2.28
3.82
1.2
1.4
396.1
305.4
pmol/l
0.31
22
99
24
103
2.35
3.68
1.6
1.5
2325.5
1742.5
e6/l
0.29
19
67
140
1014
1.43
3.65
3.0
3.2
—
—
—
0
0
29
137
2.14
3.57
2.1
2.8
0.8
0.9
nmol/l
0.14
23
99
57
346
1.68
3.32
2.2
2.9
—
—
—
0
0
41
226
1.84
3.31
1.4
1.6
—
—
—
0
0
47
274
1.74
3.17
1.6
1.6
89.0
120.8
u/ml
0.87
12
47
263
2144
1.28
3.16
1.4
1.5
20.7
20.3
nmol/l
0.19
235
1847
212
1685
1.31
3.08
3.1
3.1
1.7
1.5
e6/l
0.13
128
922
61
385
1.61
3.07
1.6
2.0
—
—
—
0
0
36
196
1.86
3.04
1.3
1.1
—
—
—
0
0
46
272
1.72
2.97
6.1
7.1
1385.2
422.0
iu/ml
—
5
43
50
309
1.64
2.76
1.2
1.4
—
—
—
0
0
94
678
1.42
2.57
2.0
1.7
—
—
—
0
0
20
94
2.14
2.55
1.5
1.4
110824.5
22722.5
e6/l
0.78
11
52
101
743
1.39
2.47
3.6
4.3
1.2
1.2
mmol/l
0.16
92
655
47
297
1.60
2.41
1.2
1.4
284.5
253.6
u/ml
0.30
36
172
14
58
2.43
2.37
1.3
1.8
—
—
—
0
0
14
58
2.43
2.37
1.3
1.8
—
—
—
0
0
79
561
1.43
2.37
3.9
3.5
4.6
4.7
pmol/l
0.32
70
503
41
255
1.63
2.26
2.0
1.8
—
—
—
0
0
15
66
2.29
2.25
1.3
1.8
—
—
—
0
0
15
66
2.29
2.25
1.4
2.0
—
—
—
0
0
17
80
2.14
2.19
1.3
1.8
—
—
—
0
0
329
2857
1.20
2.17
2.7
2.8
2494.2
5126.3
umol/l
0.88
301
2537
14
61
2.31
2.15
1.2
1.2
1.1
1.0
ratio
—
5
20
0
51
0.00
1.89
0.0
2.8
—
40.9
—
0
51
427
3834
1.17
1.88
1.9
1.9
94.9
95.6
pmol/l
0.12
245
2102
11
46
2.40
1.85
1.9
2.8
221.9
196.2
u/l
0.70
11
46
305
2668
1.19
1.84
4.0
3.5
0.0
0.0
estimate
0.88
94
920
35
222
1.59
1.83
3.4
5.0
5.0
5.0
kpa
0.11
35
217
129
1033
1.28
1.82
2.7
2.6
0.2
0.2
g/l
0.96
124
969
20
349
0.57
1.78
1.3
1.3
97.6
220.3
miu/ml
—
9
161
11
47
2.35
1.78
1.0
1.1
—
—
—
0
0
10
215
0.46
1.70
1.1
1.5
—
—
—
0
0
190
1605
1.21
1.68
1.6
1.7
1288.3
1172.0
nmol/l
1.03
152
1232
5
14
3.58
1.61
1.0
1.6
—
—
—
0
0
6
142
0.42
1.52
1.2
1.1
—
—
—
0
0
152
1270
1.22
1.51
2.9
3.3
10.2
8.5
umol/l
0.44
139
1127
10
203
0.49
1.48
1.2
1.4
—
—
—
0
0
10
203
0.49
1.48
1.2
1.4
—
—
—
0
0
9
37
2.44
1.48
1.3
1.5
—
—
—
0
0
10
202
0.49
1.46
1.2
1.4
—
—
—
0
0
10
202
0.49
1.46
1.2
1.4
—
—
—
0
0
17
96
1.78
1.39
1.3
1.8
—
—
—
0
0
17
96
1.78
1.39
1.3
1.8
—
—
—
0
0
17
96
1.78
1.39
1.3
1.8
—
—
—
0
0
6
23
2.62
1.37
1.3
1.4
—
—
—
0
0
534
4961
1.13
1.36
4.6
4.4
0.0
0.0
estimate
0.50
107
963
44
316
1.41
1.34
1.3
1.1
—
—
—
0
0
45
325
1.40
1.33
1.6
1.8
—
—
—
0
0
534
4968
1.13
1.32
3.6
3.2
0.0
0.0
estimate
0.00
103
929
6
24
2.51
1.30
1.2
1.3
—
—
—
0
0
16
91
1.77
1.29
1.3
2.9
—
—
—
0
0
31
210
1.49
1.28
1.4
1.4
—
—
—
0
0
6
135
0.44
1.27
1.2
1.1
—
—
—
0
0
9
45
2.01
1.23
2.3
2.5
—
—
—
0
0
42
306
1.38
1.20
1.5
2.5
12374.3
4038.1
u/l
—
10
119
18
109
1.66
1.19
2.8
2.6
105.7
105.2
mmol/l
0.26
18
109
18
109
1.66
1.19
2.8
2.6
4.0
4.1
mmol/l
0.81
18
109
95
779
1.24
1.17
7.0
4.7
2.2
1.4
mmol/l
2.01
73
581
11
57
1.94
1.17
1.0
1.2
188.9
240.5
iu/ml
0.31
11
57
43
317
1.37
1.16
1.3
1.1
—
—
—
0
0
149
1721
0.85
1.11
2.0
1.9
1.7
1.5
%
0.34
132
1533
7
31
2.26
1.10
1.1
1.2
100.0
89.4
%
—
7
31
7
31
2.26
1.10
1.1
1.2
—
—
—
0
0
52
399
1.32
1.09
1.2
1.4
—
—
—
0
0
422
3916
1.11
1.06
4.3
3.8
23.7
21.4
%
1.65
201
1717
14
82
1.71
1.05
1.1
1.1
—
—
—
0
0
14
82
1.71
1.05
1.1
1.1
—
—
—
0
0
11
60
1.84
1.03
2.5
3.0
1209.6
1240.2
u/ml
0.01
11
60
9
47
1.92
1.02
1.1
1.2
—
—
—
0
0
43
325
1.33
1.01
1.2
1.3
—
—
—
0
0
533
5022
1.10
0.99
3.6
3.3
0.0
0.0
estimate
0.50
105
898
5
23
2.18
0.98
1.4
1.0
—
—
—
0
0
32
232
1.39
0.98
2.2
2.4
128.5
132.7
g/l
0.40
22
168
14
85
1.65
0.94
1.1
1.1
—
—
—
0
0
14
85
1.65
0.94
1.1
1.1
—
—
—
0
0
14
85
1.65
0.94
1.1
1.1
—
—
—
0
0
7
37
1.90
0.94
2.7
4.7
—
—
—
0
0
6
119
0.50
0.94
1.2
1.0
—
—
—
0
0
186
1658
1.14
0.92
2.1
3.2
2.4
2.4
mmol/l
0.31
158
1466
6
30
2.00
0.87
1.3
2.3
—
—
—
0
0
348
3243
1.10
0.80
3.4
3.4
2.3
2.4
mmol/l
0.78
307
2880
412
3871
1.09
0.79
3.7
3.3
—
—
—
0
0
32
242
1.33
0.79
1.8
1.7
11565.1
15644.8
e6/l
0.39
21
183
20
140
1.44
0.77
1.1
1.4
0.5
0.6
nmol/l
0.76
20
133
0
28
0.00
0.76
0.0
1.8
—
0.2
—
0
17
47
378
1.25
0.75
1.3
1.2
0.3
1.1
u/ml
—
8
30
34
264
1.30
0.72
2.0
2.6
0.0
0.0
g/l
0.50
28
250
7
40
1.75
0.71
1.1
1.1
—
—
—
0
0
38
474
0.80
0.68
1.4
1.8
2.5
3.7
mg/l
1.02
28
338
22
295
0.74
0.67
1.5
1.6
442.7
531.8
mg/l
1.26
22
278
37
296
1.26
0.64
1.4
1.5
260.3
278.6
ug/g
0.17
19
173
11
165
0.66
0.63
2.9
3.8
2.6
1.4
%
0.49
11
141
231
2138
1.10
0.63
1.7
1.5
—
—
—
0
0
12
79
1.52
0.62
1.3
1.5
1.0
1.0
g/l
0.04
12
79
19
138
1.38
0.62
1.1
1.4
—
0.4
nmol/l
—
0
10
31
244
1.28
0.61
1.3
2.6
0.0
0.0
g/l
0.00
25
230
8
50
1.60
0.61
1.3
1.4
—
—
—
0
0
8
50
1.60
0.61
1.3
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
33
263
1.26
0.60
1.2
1.3
—
—
—
0
0
8
52
1.54
0.59
1.1
1.3
—
51.3
—
0
8
35
431
0.81
0.58
1.7
1.9
215.3
218.3
pmol/l
0.06
35
408
8
53
1.51
0.58
1.3
2.5
20.7
175.1
ug/l
—
8
46
306
2878
1.08
0.58
2.9
2.8
0.7
0.7
ug/l
0.03
185
1770
28
353
0.79
0.57
1.6
1.5
—
—
—
0
0
27
211
1.29
0.57
1.1
1.2
23.4
36.6
u/ml
—
5
18
44
365
1.21
0.57
1.7
1.6
13.8
0.1
iu/ml
—
9
66
33
265
1.25
0.57
1.5
1.4
—
—
—
0
0
5
89
0.56
0.56
1.0
1.0
—
—
—
0
0
5
89
0.56
0.56
1.0
1.1
314.0
289.5
mg/l
—
5
80
44
366
1.21
0.56
1.9
1.7
—
—
—
0
0
308
2907
1.08
0.54
1.6
1.7
1.4
1.4
mmol/l
0.30
261
2472
20
151
1.33
0.54
1.6
2.1
1.6
1.6
mmol/l
0.02
20
145
36
295
1.23
0.53
1.7
2.7
0.3
1.2
g/l
1.97
28
270
146
1595
0.90
0.53
1.2
1.2
1.7
10.1
u/ml
6.42
55
643
156
1695
0.91
0.51
1.2
1.3
41.8
31.7
iu/ml
0.37
43
516
18
135
1.34
0.51
1.2
1.1
—
—
—
0
0
15
109
1.38
0.51
1.8
1.4
—
—
—
0
0
55
637
0.86
0.50
2.4
2.1
—
—
—
0
0
30
243
1.24
0.50
1.3
2.6
0.0
0.0
g/l
0.00
25
230
18
136
1.33
0.49
1.5
1.9
—
—
—
0
0
7
45
1.56
0.49
1.1
1.1
—
—
—
0
0
507
4885
1.06
0.48
4.2
4.4
2.1
2.3
ug/l
0.58
452
4435
16
119
1.35
0.48
1.5
2.0
—
—
—
0
0
16
211
0.76
0.47
1.1
1.6
—
—
—
0
0
7
48
1.46
0.47
1.1
1.4
—
—
—
0
0
7
48
1.46
0.47
1.1
1.4
—
—
—
0
0
22
173
1.28
0.46
1.2
1.1
—
—
—
0
0
18
232
0.77
0.46
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
84
0.59
0.45
1.0
1.1
—
—
—
0
0
12
86
1.40
0.44
2.3
2.5
—
—
—
0
0
788
7705
1.06
0.44
3.2
3.3
48.4
52.5
u/l
0.99
742
7298
18
229
0.78
0.42
1.4
1.4
—
—
—
0
0
84
931
0.90
0.42
3.6
4.6
3.1
23.1
ug/l
1.56
70
773
5
32
1.56
0.42
6.4
6.0
—
—
—
0
0
66
586
1.13
0.41
1.0
1.0
—
—
—
0
0
13
96
1.36
0.41
1.6
2.5
22.0
19.1
mg/l
—
7
32
45
519
0.86
0.41
2.4
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
2.1
—
0
7
8
60
1.34
0.40
1.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
7
103
0.68
0.39
3.6
4.6
—
—
—
0
0
13
97
1.34
0.39
1.3
3.0
11.9
11.3
%
—
7
56
110
1010
1.10
0.39
2.2
2.6
32.6
85.3
u/l
0.60
94
889
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
111
1205
0.91
0.38
1.8
1.8
—
—
—
0
0
11
80
1.38
0.38
1.8
1.6
3.3
3.6
mg/l
0.21
11
75
21
258
0.81
0.38
1.1
1.6
3.6
3.8
mmol/l
0.62
21
240
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
14
181
0.77
0.38
1.0
1.1
1.5
2.6
u/ml
—
6
87
9
67
1.35
0.38
2.7
2.4
—
—
—
0
0
9
67
1.35
0.38
2.7
2.4
—
—
—
0
0
24
197
1.22
0.38
2.2
4.1
929.3
269.1
u/ml
0.32
24
188
21
257
0.81
0.37
1.7
1.8
343.1
1029.5
e6/l
0.64
16
200
21
257
0.81
0.37
1.7
1.7
3.9
48.4
e6/l
1.14
16
192
37
318
1.17
0.37
2.1
2.4
3.2
3.1
g/l
0.35
27
257
18
223
0.80
0.36
1.8
1.5
—
—
—
0
0
15
118
1.27
0.33
1.2
1.5
0.3
0.3
nmol/l
—
9
95
22
182
1.21
0.33
1.1
1.1
—
—
—
0
0
38
332
1.15
0.32
1.1
1.1
—
—
—
0
0
71
647
1.10
0.31
1.2
1.2
89.9
159.5
iu/ml
1.23
28
246
125
1328
0.94
0.28
2.0
2.3
13.0
13.6
nmol/l
0.41
112
1198
31
271
1.15
0.27
1.3
2.5
37.6
38.1
g/l
0.17
25
240
33
290
1.14
0.27
3.9
3.6
34.6
34.4
mg/l
0.01
24
232
33
290
1.14
0.27
3.9
3.6
31.7
72.8
mg/l
1.14
23
230
19
225
0.84
0.26
1.1
1.2
—
—
—
0
0
13
104
1.25
0.26
1.1
1.1
—
—
—
0
0
43
478
0.90
0.26
2.1
2.0
33.3
39.7
u/l
1.22
36
429
13
160
0.81
0.26
1.3
1.3
—
—
—
0
0
5
74
0.67
0.26
1.0
1.1
—
—
—
0
0
95
1013
0.93
0.24
2.3
2.3
369.8
360.5
nmol/l
0.20
84
947
14
115
1.22
0.23
1.4
1.3
—
—
—
0
0
13
106
1.23
0.23
1.5
1.5
1.0
1.2
promille
0.38
13
85
38
342
1.11
0.23
2.0
2.3
3.6
3.9
g/l
0.68
26
252
38
342
1.11
0.23
2.0
2.3
—
—
—
0
0
38
342
1.11
0.23
2.0
2.3
6.9
7.2
g/l
0.51
27
264
13
157
0.83
0.22
3.5
3.1
20.8
21.2
nmol/l
0.05
13
150
25
219
1.14
0.22
1.2
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
5.4
—
—
—
0
0
0
11
0.00
0.21
0.0
5.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
51
470
1.09
0.20
1.5
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
35
317
1.11
0.19
2.1
2.4
10.0
10.4
g/l
0.22
28
278
202
1952
1.04
0.19
1.5
1.7
79042343.9
40350239.9
pmol/l
0.20
167
1658
18
156
1.16
0.18
1.8
2.3
—
1546.7
—
0
6
323
3152
1.03
0.18
3.6
4.1
7.4
9.5
mg/mmol
0.54
217
2095
15
128
1.17
0.18
1.3
1.2
73.3
98.0
%
2.26
15
121
11
132
0.83
0.18
1.5
1.5
—
—
—
0
0
116
1212
0.95
0.17
4.1
4.3
31.4
31.1
%
0.11
86
846
13
110
1.18
0.17
1.1
1.3
—
—
—
0
0
23
205
1.12
0.17
2.0
3.5
4.1
4.2
e9/l
0.03
23
205
8
69
1.16
0.16
1.1
1.2
—
—
—
0
0
12
141
0.85
0.16
1.1
1.0
—
—
—
0
0
8
72
1.11
0.16
1.0
1.0
—
—
—
0
0
6
79
0.76
0.15
1.5
1.6
—
—
—
0
0
10
119
0.84
0.15
1.0
1.1
—
—
—
0
0
9
78
1.15
0.15
2.3
1.6
—
—
—
0
0
12
102
1.18
0.15
1.1
1.2
—
—
—
0
0
9
80
1.13
0.15
1.1
1.2
—
—
—
0
0
9
81
1.11
0.15
1.1
1.2
—
—
—
0
0
134
1388
0.96
0.15
2.5
2.8
123.4
143.5
ug/g
0.26
105
1146
10
118
0.85
0.14
2.3
1.4
—
—
—
0
0
23
208
1.11
0.14
2.6
2.9
16.7
16.8
%
—
8
114
28
257
1.09
0.13
1.1
1.1
0.9
3.4
u/ml
1.92
14
133
18
161
1.12
0.13
1.4
1.6
—
—
—
0
0
23
211
1.09
0.11
2.3
3.9
57.9
55.9
%
0.33
23
211
10
115
0.87
0.10
1.1
1.2
1.6
1.4
nmol/l
—
10
99
59
564
1.05
0.10
1.4
1.3
—
—
—
0
0
244
2481
0.98
0.09
1.3
1.3
3.1
1.6
u/ml
0.58
68
667
20
184
1.09
0.09
1.0
1.1
1.5
1.5
g/l
0.17
20
168
221
2248
0.98
0.09
4.2
3.4
1.0
1.0
kg/l
0.81
40
306
6
55
1.09
0.09
1.3
1.7
—
1021375.0
—
0
6
71
686
1.04
0.08
1.2
1.3
20.3
60.1
au/ml
—
5
32
5
61
0.82
0.08
1.2
1.3
—
—
—
0
0
7
81
0.86
0.07
1.3
1.1
—
79.0
—
0
6
402
4058
0.99
0.07
2.2
2.3
77.5
74.0
nmol/l
1.43
371
3690
131
1284
1.02
0.07
1.9
2.0
—
—
—
0
0
8
91
0.88
0.06
1.9
2.0
—
—
—
0
0
12
132
0.91
0.06
1.6
1.5
—
—
—
0
0
9
101
0.89
0.06
2.3
1.5
—
—
—
0
0
12
131
0.92
0.05
1.5
1.5
—
—
—
0
0
16
171
0.93
0.05
1.1
1.1
—
—
—
0
0
12
130
0.92
0.04
1.6
1.5
—
—
—
0
0
12
130
0.92
0.04
1.6
1.5
—
—
—
0
0
37
382
0.97
0.04
3.3
3.8
33.9
3735.5
u/ml
0.78
32
321
12
129
0.93
0.03
1.6
1.5
—
—
—
0
0
103
1017
1.01
0.03
1.5
1.5
—
—
—
0
0
142
1407
1.01
0.02
2.0
2.1
—
—
—
0
0
339
3404
0.99
0.02
3.1
3.4
7.9
8.4
mmol/l
1.30
295
2907
12
114
1.05
0.00
1.7
1.5
—
—
—
0
0
76
754
1.01
0.00
2.3
2.4
17.9
19.6
au/ml
—
6
42
15
154
0.97
0.00
1.2
1.3
—
—
—
0
0
15
148
1.01
0.00
1.3
1.5
102.6
68.3
pmol/l
—
7
48
14
139
1.01
0.00
2.1
1.7
—
—
—
0
0
24
239
1.00
0.00
2.1
1.8
2.6
5.5
iu/l
2.29
11
82
10
103
0.97
0.00
2.4
2.7
—
—
—
0
0
38
385
0.99
0.00
1.7
1.5
38.0
21.4
iu/l
1.77
32
312
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
98.1
—
0
7
0
9
0.00
0.00
0.0
7.2
—
—
—
0
0
0
9
0.00
0.00
0.0
6.7
—
—
—
0
0
0
9
0.00
0.00
0.0
5.0
—
420.4
—
0
9
0
7
0.00
0.00
0.0
5.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
3.5
—
0
6
0
8
0.00
0.00
0.0
2.3
—
0.5
—
0
8
8
89
0.90
0.00
1.7
1.2
2.7
2.0
mmol/l
—
8
82
6
64
0.94
0.00
1.5
3.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
8
87
0.92
0.00
1.1
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
16.6
—
0
8
0
5
0.00
0.00
0.0
1.6
—
478.4
—
0
5
5
59
0.85
0.00
1.8
2.2
—
—
—
0
0
5
50
1.00
0.00
1.0
1.4
197.8
473.4
u/l
—
5
45
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_BICUSP_AORTIC_VALVE – Bicuspidal aortic valve syndrome
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).