No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
324 |
4. Check minimum number of eventsNone |
324 |
5. Include endpointsNone |
324 |
6. Filter based on genotype QC (FinnGen only) |
311 |
Control definitions (FinnGen only)
- Control exclude
- N14_GLOMERULAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N00-N08
- Name in latin
- Haematuria recidiva et persistens
Similar endpoints
↥List of similar endpoints to
Recurrent and persistent haematuria
based on the number of shared cases.
Similar with more cases:
- Glomerulonephritis
- Glomerular diseases
- All chronic kidney diseases
- All kidney diseases
- Genitourinary diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2501 | 1150 | 1325 |
| Only index persons | 2128 | 1044 | 1084 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 52.05 | 43.41 | 59.18 |
| Only index persons | 48.62 | 41.87 | 55.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 311 | 146 | 165 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.08 |
| Median age at first event (years) | 52.67 | 44.05 | 60.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 324
- Matched controls
- 3240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N02.9
ICD-10 Finland
Recurrent and persistent haematuria, unspecified
+∞
172.9
150
*
R31
ICD-10 Finland
Unspecified haematuria
11.9
102.7
136
186
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
59.2
55
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
30.3
59.1
40
15
KA1AE
NOMESCO Finland
Kidney ultrasound examination
19.1
47.8
39
23
A11CC03
ATC
alfacalcidol; systemic
19.8
46.2
37
21
UKC02
NOMESCO Finland
Cystoscopy
5.2
41.3
113
302
N02.8
ICD-10 Finland
Recurrent and persistent haematuria, other
+∞
36.1
34
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
8.2
34.0
49
69
N02.0
ICD-10 Finland
Recurrent and persistent haematuria, minor glomerular abnormality
+∞
32.9
31
*
N02
ICD-10 Finland
Recurrent and persistent haematuria
357.3
32.5
32
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
40.3
29.0
36
10
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.1
28.3
46
74
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
52.3
28.0
33
7
N18.8
ICD-10 Finland
Other chronic renal failure
25.1
25.9
36
16
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
54.9
25.7
30
6
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
24.3
23
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
24.3
23
*
Z94.0
ICD-10 Finland
Kidney transplant status
94.0
24.0
26
*
L04AA06
ATC
mycophenolic acid; systemic
26.2
22.6
31
13
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
21.1
20
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
223.8
20.8
21
*
A12AA04
ATC
calcium carbonate; oral
29.3
20.4
27
10
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
78.2
19.9
22
*
B03XA01
ATC
erythropoietin; parenteral
74.5
18.9
21
*
N02BE, ,
ICD-10 Finland
+∞
18.9
18
*
N02.2
ICD-10 Finland
Recurrent and persistent haematuria, diffuse membranous glomerulonephritis
+∞
18.9
18
*
127
Kela drug reimbursment
Transplant complication
24.5
18.0
25
11
N02.1
ICD-10 Finland
Recurrent and persistent haematuria, focal and segmental glomerular lesions
+∞
17.9
17
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
17.5
64
202
R80
ICD-10 Finland
Isolated proteinuria
44.8
17.5
21
5
N02.3
ICD-10 Finland
Recurrent and persistent haematuria, diffuse mesangial proliferative glomerulonephritis
+∞
16.8
16
*
137
Kela drug reimbursment
Uraemia requiring dialysis
95.1
16.7
18
*
B03XA02
ATC
darbepoetin alfa; parenteral
20.5
15.8
23
12
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.8
15.6
37
84
C03CA01
ATC
furosemide; systemic
2.7
15.6
122
595
L04AD02
ATC
tacrolimus; systemic
47.4
15.2
18
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
156.8
14.6
15
*
B05DA
ATC
Isotonic solutions
156.8
14.6
15
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
28.7
14.4
19
7
N18.0
ICD-10 Finland
End-stage renal disease
44.6
14.2
17
*
B05DB
ATC
Hypertonic solutions
+∞
13.6
13
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
145.9
13.6
14
*
Z49.2
ICD-10 Finland
Other dialysis
145.9
13.6
14
*
205
Kela drug reimbursment
Chronic hypertension
2.6
13.5
100
469
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.7
13.5
22
35
TK800
NOMESCO Finland
Hemodialysis
11.7
13.3
24
22
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.4
12.9
34
84
J01MA02
ATC
ciprofloxacin; systemic
2.3
11.5
147
870
Z49.0
ICD-10 Finland
Preparatory care for dialysis
36.4
11.4
14
*
V03AE01
ATC
polystyrene sulfonate; oral
20.9
11.2
16
8
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
26.1
11.2
15
6
L04AD01
ATC
ciclosporin; systemic
12.5
11.0
19
16
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.7
10.9
66
277
C02AC05
ATC
moxonidine; oral
5.1
10.7
23
48
V03AE02
ATC
sevelamer; oral
113.5
10.5
11
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
113.5
10.5
11
*
N02.4
ICD-10 Finland
Recurrent and persistent haematuria, diffuse endocapillary proliferative glomerulonephritis
+∞
10.5
10
*
H02AB04
ATC
methylprednisolone; systemic
2.8
10.4
61
252
N30.0
ICD-10 Finland
Acute cystitis
2.8
10.4
61
252
A41.9
ICD-10 Finland
Sepsis, unspecified
4.8
9.9
23
51
C09AA02
ATC
enalapril; systemic
2.5
9.9
72
330
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
27.0
9.9
13
5
B01AB10
ATC
tinzaparin; parenteral
3.2
9.9
43
150
M05BA04
ATC
alendronic acid; oral
3.5
9.6
34
104
L04AX01
ATC
azathioprine; systemic
4.7
9.5
22
49
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
9.4
9
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
9.4
9
*
M04AA01
ATC
allopurinol; systemic
2.7
9.1
56
236
L04AA01
ATC
[U] ciclosporin
16.2
9.1
14
9
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
24.8
9.0
12
5
A02BC01
ATC
omeprazole; systemic
2.2
8.8
100
554
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
8.8
55
234
A02BC02
ATC
pantoprazole; systemic
2.1
8.7
218
1608
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
8.6
99
551
N02AX02
ATC
tramadol; systemic, rectal
2.0
8.5
143
915
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.4
8.3
21
50
ZX120
NOMESCO Finland
Intravenous
2.9
8.3
42
160
C08CA01
ATC
amlodipine; oral
2.0
8.0
124
765
R50.9
ICD-10 Finland
Fever, unspecified
2.4
8.0
61
284
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
7.9
124
768
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
15.5
7.8
12
8
J01DB01
ATC
cefalexin; oral
2.4
7.7
272
2228
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.7
147
973
5997A
ICD-9 Finland
Other disorders of urethra and urinary tract, Haematuria
25.7
7.6
10
*
R04.0
ICD-10 Finland
Epistaxis
3.2
7.5
30
99
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.5
89
498
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
7.4
107
643
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
7.3
77
411
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.3
98
573
N20.1
ICD-10 Finland
Calculus of ureter
4.1
7.3
20
51
R60.0
ICD-10 Finland
Localized oedema
2.6
7.2
44
184
C09CA01
ATC
losartan; oral
2.1
7.1
87
492
K65.0
ICD-10 Finland
Acute peritonitis
11.3
6.9
12
11
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
6.8
22
63
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
6.7
36
141
UJF32
NOMESCO Finland
Coloscopy
2.0
6.7
83
469
R33
ICD-10 Finland
Retention of urine
2.6
6.7
39
160
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
6.5
58
289
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
71.2
6.4
7
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
71.2
6.4
7
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
6.4
45
202
UKB02
NOMESCO Finland
Retrograde ureteroscopy
11.3
6.3
11
10
B34.9
ICD-10 Finland
Viral infection, unspecified
5.2
6.3
18
36
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
6.3
6
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
6.3
6
*
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
6.3
6
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
6.3
6
*
A12AA12
ATC
[U] calcium acetate
+∞
6.3
6
*
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
6.3
6
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
6.3
6
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
6.3
6
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.4
6.3
22
67
R11
ICD-10 Finland
Nausea and vomiting
2.6
6.2
37
153
RS220, ,
NOMESCO Finland
12.8
6.1
10
8
ZXA05
NOMESCO Finland
Left side
2.0
6.1
82
476
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
80
205
4.85
29.94
11.2
3.1
1.58
2.00
mmol/l
0.52
71
155
191
991
3.26
24.05
10.9
4.5
34.42
35.74
g/l
2.44
183
937
146
661
3.20
23.01
8.8
3.6
29.58
9.09
mg/mmol
2.71
123
420
203
1149
3.05
20.92
16.6
6.4
1.21
1.21
mmol/l
0.33
182
977
170
875
2.98
20.83
9.6
3.0
—
—
—
0
0
87
312
3.44
19.78
5.2
2.0
23.23
22.84
%
0.09
76
270
118
511
3.06
19.52
8.1
2.4
4.24
6.20
e6/l
0.57
111
455
208
1225
2.95
19.35
7.5
3.4
0.00
0.00
estimate
0.50
40
254
208
1244
2.88
18.46
7.7
3.5
0.00
0.00
estimate
-0.00
35
223
204
1224
2.80
17.71
10.4
4.7
0.00
0.00
estimate
0.50
35
237
146
743
2.76
17.52
9.6
3.0
98.89
146.96
e6/l
0.22
120
573
92
365
3.12
17.50
5.0
2.0
12.86
13.46
umol/l
0.34
87
336
138
691
2.74
16.98
7.4
2.9
7.73
8.04
mmol/l
0.34
121
588
15
0
+∞
15.75
1.3
0.0
—
—
—
0
0
26
43
6.49
15.37
7.8
5.7
184.20
313.17
iu/ml
—
5
6
178
1050
2.54
15.17
14.0
5.6
1.21
1.21
mmol/l
0.03
169
954
125
625
2.63
15.08
3.9
2.6
5933.64
7206.36
umol/l
0.11
118
543
28
55
5.48
13.90
1.8
1.3
—
—
—
0
0
128
669
2.51
13.86
8.6
3.0
0.25
0.36
e6/l
0.82
105
501
27
52
5.57
13.68
1.5
1.2
283.19
216.84
u/ml
0.40
21
32
23
18
13.66
13.63
1.1
1.1
—
—
—
0
0
141
782
2.42
13.28
5.2
3.2
2.32
2.35
mmol/l
1.65
129
695
29
64
4.88
12.63
2.6
3.5
—
1.32
—
0
9
27
56
5.17
12.62
1.4
1.3
—
—
—
0
0
161
967
2.32
12.41
7.9
3.5
—
—
—
0
0
29
65
4.80
12.40
2.6
3.7
45.10
141.14
mg/l
0.53
20
55
29
65
4.80
12.40
2.6
3.7
33.13
31.14
mg/l
0.11
20
55
21
18
12.39
12.00
3.5
3.1
—
—
—
0
0
173
1086
2.27
11.83
18.8
14.0
1.11
1.26
inr
2.10
53
339
64
254
2.89
11.81
7.2
8.9
1.04
1.30
mmol/l
0.13
47
203
11
0
+∞
11.52
5.9
0.0
—
—
—
0
0
110
584
2.34
11.07
2.4
2.0
2.82
3.00
mg/l
0.41
99
494
83
398
2.46
10.42
5.9
2.8
1.80
0.95
e6/l
0.70
54
223
225
1625
2.26
10.29
10.2
4.2
183.30
258.62
e6/l
—
10
29
42
141
3.27
10.28
4.1
3.0
1.78
1.46
mmol/l
0.18
29
108
171
1116
2.13
10.07
4.6
2.5
136.43
116.54
ug/l
0.68
159
1030
60
251
2.71
9.94
7.7
8.9
11.61
12.10
kpa
0.26
55
242
60
251
2.71
9.94
7.6
8.9
4.93
5.05
kpa
0.45
55
240
206
1462
2.12
9.50
14.9
9.4
4.39
4.07
e9/l
1.18
194
1285
152
967
2.08
9.38
3.3
2.2
71.82
74.45
nmol/l
0.63
146
864
78
382
2.37
9.25
6.3
2.9
1.89
2.24
e6/l
0.21
48
211
21
32
6.94
8.81
5.4
4.4
—
5455.00
—
0
5
246
1907
2.20
8.52
13.0
7.1
76.33
77.51
u/l
0.15
239
1785
37
132
3.04
8.16
7.6
5.1
23.66
24.65
mmol/l
0.84
37
132
43
177
2.65
7.29
3.6
2.6
52.00
69.89
ml/min/173m2
1.30
22
74
196
1444
1.90
7.24
9.4
4.7
6.64
6.64
mmol/l
0.01
190
1343
76
415
2.09
6.74
2.1
1.6
1362.78
1200.43
nmol/l
0.61
60
311
175
1269
1.82
6.54
7.6
6.2
12.39
11.23
umol/l
0.30
175
1205
138
933
1.83
6.47
2.4
1.9
91.78
94.53
pmol/l
0.36
81
493
162
1156
1.80
6.31
3.6
2.6
—
—
—
0
0
95
574
1.93
6.30
2.7
2.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
67
3.45
6.26
3.8
2.3
0.28
0.31
u/ml
0.18
12
37
92
554
1.92
6.15
8.1
3.6
1.02
1.02
kg/l
0.65
18
81
291
2524
2.50
6.12
32.1
13.6
20.78
23.29
mg/l
0.82
268
1974
39
167
2.52
6.10
1.9
1.5
—
—
—
0
0
126
842
1.81
6.05
4.7
3.0
32.53
32.58
u/l
0.00
121
799
72
403
2.01
5.92
2.5
1.8
—
—
—
0
0
81
475
1.94
5.82
2.1
1.7
394.25
28398492.81
pmol/l
0.79
72
412
92
564
1.88
5.78
1.7
1.5
16.72
20.76
nmol/l
2.68
85
484
54
274
2.16
5.74
2.5
1.8
—
—
—
0
0
19
57
3.48
5.53
3.2
2.2
192.49
108.38
ug/min
0.49
14
35
103
667
1.80
5.38
8.8
3.7
0.03
0.00
estimate
0.40
31
230
108
728
1.73
4.83
2.8
2.1
146.25
328.43
u/l
1.07
103
698
8
7
11.67
4.81
1.0
1.0
—
—
—
0
0
51
273
2.03
4.70
2.5
1.8
—
—
—
0
0
12
23
5.37
4.50
1.2
1.2
—
—
—
0
0
46
241
2.06
4.49
5.1
3.4
—
—
—
0
0
130
936
1.65
4.47
5.3
3.7
46.60
43.25
ng/l
0.10
96
639
288
2564
2.11
4.41
37.8
15.1
4.05
3.97
mmol/l
3.72
283
2488
18
61
3.07
4.35
1.3
1.2
—
—
—
0
0
21
78
2.81
4.34
1.5
2.4
—
—
—
0
0
287
2558
2.07
4.28
37.2
15.0
139.65
139.67
mmol/l
0.06
282
2483
13
31
4.32
4.06
1.1
1.1
—
—
—
0
0
22
91
2.52
3.72
1.5
1.3
—
—
—
0
0
85
582
1.62
3.44
1.9
1.7
0.83
1.25
mg/l
1.94
65
448
221
1886
1.54
3.22
5.6
3.7
15.36
11.20
mm/h
2.73
211
1740
220
1876
1.54
3.22
4.2
3.8
14.61
14.67
pmol/l
0.14
201
1708
66
435
1.65
3.08
4.7
3.0
2.46
2.44
mmol/l
0.84
55
388
17
70
2.51
2.93
1.8
1.4
—
—
—
0
0
10
27
3.79
2.90
9.1
4.7
6.74
6.32
mmol/l
—
10
22
93
675
1.53
2.88
4.0
3.1
3390.16
1320.81
ng/l
1.17
82
569
65
434
1.62
2.88
6.6
3.5
4027.49
199.85
ng/l
0.49
49
326
265
2403
1.56
2.50
4.6
3.8
1.36
1.26
mmol/l
1.25
249
2210
13
51
2.61
2.47
1.5
1.4
—
—
—
0
0
6
12
5.07
2.41
2.7
3.5
—
—
—
0
0
6
12
5.07
2.41
2.7
3.5
—
—
—
0
0
275
2524
1.59
2.35
5.5
4.5
2.62
2.77
mmol/l
2.12
262
2333
6
13
4.68
2.28
2.3
2.7
133.50
57.38
nmol/l
—
6
13
28
158
1.85
2.26
1.7
1.4
—
—
—
0
0
5
10
5.06
2.08
1.0
1.5
—
—
—
0
0
5
10
5.06
2.08
1.0
1.5
—
—
—
0
0
13
56
2.38
2.07
5.7
2.1
4.86
4.96
kpa
0.27
13
56
58
411
1.50
1.98
1.1
1.3
15.66
8.65
u/ml
0.19
22
169
12
51
2.40
1.97
1.9
1.5
—
—
—
0
0
268
2472
1.49
1.96
5.1
4.1
1.35
1.44
mmol/l
3.46
255
2287
262
2407
1.46
1.95
5.3
4.2
5.90
5.88
mmol/l
0.09
247
2209
269
2484
1.49
1.95
5.2
4.2
4.43
4.63
mmol/l
2.58
257
2308
5
11
4.60
1.95
1.4
2.5
10.60
13.00
%
—
5
11
260
2389
1.45
1.90
27.9
12.4
72.70
84.45
ml/min/173m2
8.03
219
1951
24
137
1.81
1.89
1.8
1.7
—
—
—
0
0
247
2252
1.41
1.86
7.9
5.4
39.93
39.55
mmol/mol
0.25
237
2107
19
102
1.92
1.80
1.6
2.2
2914.80
3196.92
u/l
—
6
42
8
29
2.80
1.80
1.6
1.1
—
—
—
0
0
14
67
2.14
1.78
1.8
1.4
—
—
—
0
0
6
18
3.38
1.75
1.7
1.6
—
—
—
0
0
7
24
2.96
1.73
1.3
1.2
—
—
—
0
0
11
48
2.34
1.72
2.7
1.4
—
—
—
0
0
11
48
2.34
1.72
2.7
1.4
—
—
—
0
0
12
55
2.23
1.69
1.8
1.4
—
—
—
0
0
12
55
2.23
1.69
2.3
1.3
—
—
—
0
0
12
55
2.23
1.69
1.0
1.3
—
—
—
0
0
8
31
2.62
1.67
1.0
1.2
—
—
nmol/l
—
0
0
10
43
2.37
1.60
1.8
1.2
—
—
—
0
0
7
26
2.73
1.59
1.0
1.5
—
—
—
0
0
10
44
2.31
1.57
1.3
1.6
—
—
—
0
0
10
44
2.31
1.57
1.3
1.6
—
—
—
0
0
73
565
1.38
1.56
1.2
1.3
0.54
1.56
u/ml
1.77
16
150
5
15
3.37
1.53
1.0
1.3
—
—
—
0
0
7
28
2.53
1.46
1.4
1.8
—
—
—
0
0
5
16
3.16
1.44
1.0
2.1
—
—
—
0
0
5
16
3.16
1.44
2.0
1.8
—
—
—
0
0
246
2277
1.33
1.41
5.4
4.5
1.79
1.88
mu/l
0.62
229
2083
13
67
1.98
1.40
1.8
1.5
—
—
—
0
0
14
75
1.91
1.36
3.9
2.7
—
—
—
0
0
16
91
1.80
1.31
1.4
2.3
—
—
—
0
0
16
91
1.80
1.31
1.4
2.3
7.26
7.48
g/l
0.25
16
84
16
91
1.80
1.31
1.4
2.3
3.92
3.59
g/l
0.46
16
84
9
43
2.12
1.31
1.4
1.5
—
—
—
0
0
8
34
2.39
1.30
1.5
1.4
—
—
—
0
0
8
34
2.39
1.30
2.0
1.2
—
—
—
0
0
15
84
1.82
1.29
1.5
2.3
10.71
10.46
g/l
0.09
15
76
5
19
2.66
1.22
1.0
1.1
—
—
—
0
0
43
319
1.40
1.19
2.9
2.8
11.83
7.94
umol/l
0.40
36
271
8
38
2.13
1.19
1.5
1.4
—
—
—
0
0
296
2842
1.48
1.18
44.8
19.6
39.03
40.39
%
2.64
279
2690
15
87
1.76
1.17
1.5
2.3
3.14
3.00
g/l
0.21
15
80
55
428
1.34
1.15
1.2
1.3
72.55
32.89
iu/ml
0.40
16
137
8
40
2.02
1.13
1.3
1.0
—
—
—
0
0
19
120
1.62
1.11
1.4
2.4
37.00
50.31
u/ml
0.20
19
115
7
31
2.29
1.11
1.0
1.4
—
—
—
0
0
7
31
2.29
1.11
1.0
1.4
—
—
—
0
0
7
31
2.29
1.11
1.4
1.8
—
—
—
0
0
8
41
1.97
1.09
3.9
3.1
59.88
58.24
%
—
8
41
5
21
2.40
1.09
1.0
1.1
—
—
—
0
0
7
32
2.21
1.08
1.3
1.3
—
—
—
0
0
7
32
2.21
1.08
1.6
1.4
—
—
—
0
0
189
1728
1.23
1.02
3.5
3.3
—
—
—
0
0
105
904
1.24
1.01
5.3
5.1
3.86
2.72
ug/l
0.51
93
819
5
23
2.19
0.98
2.4
1.1
—
—
—
0
0
10
54
1.88
0.97
1.1
1.4
—
—
—
0
0
13
78
1.69
0.93
1.5
2.3
36.85
38.27
g/l
0.32
13
71
6
30
2.02
0.87
1.2
1.2
—
—
—
0
0
190
1754
1.20
0.87
4.5
2.9
44.28
45.28
u/l
0.09
181
1653
62
511
1.26
0.87
1.5
1.6
—
—
—
0
0
12
72
1.69
0.86
1.6
2.5
0.00
0.00
g/l
-0.00
12
67
16
106
1.54
0.80
2.0
2.0
—
—
—
0
0
15
98
1.56
0.80
3.0
1.9
—
—
—
0
0
6
34
1.78
0.76
2.5
2.7
7.05
3.94
nmol/l
—
6
34
10
59
1.72
0.76
1.8
1.5
—
—
—
0
0
10
160
0.61
0.76
1.4
1.8
—
—
—
0
0
21
150
1.43
0.75
3.1
3.5
4.55
4.54
pmol/l
0.03
21
132
5
25
2.02
0.73
1.0
1.0
—
—
—
0
0
5
26
1.94
0.71
3.0
3.3
—
—
—
0
0
12
77
1.58
0.69
1.6
2.4
0.18
0.00
g/l
0.71
12
72
11
70
1.59
0.66
1.0
1.1
—
—
—
0
0
7
44
1.60
0.65
1.9
1.4
—
—
—
0
0
5
29
1.74
0.64
2.0
2.2
—
—
—
0
0
5
29
1.74
0.64
12.2
18.8
1853.80
1518.72
nmol/l
—
5
29
5
30
1.68
0.61
1.0
1.4
28.36
16.02
ug/l
—
5
30
0
21
0.00
0.60
0.0
3.4
—
71.59
—
0
21
14
195
0.71
0.58
1.4
1.9
—
—
—
0
0
10
66
1.53
0.53
1.0
1.4
—
—
—
0
0
12
83
1.46
0.52
1.6
2.3
0.13
1.11
g/l
1.81
12
76
71
628
1.17
0.51
1.7
1.6
1.37
1.36
mmol/l
0.04
62
529
30
245
1.25
0.49
2.6
4.2
3.25
9.19
ug/l
1.81
22
200
13
93
1.41
0.49
2.7
1.7
—
—
—
0
0
8
57
1.41
0.42
1.6
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
35.81
—
0
9
0
15
0.00
0.41
0.0
1.0
—
496.22
—
0
9
0
16
0.00
0.41
0.0
1.2
—
199.03
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
8
61
1.32
0.40
1.1
1.2
—
—
—
0
0
21
169
1.26
0.40
1.2
1.3
—
31.69
—
0
12
5
76
0.65
0.36
1.8
1.4
—
—
—
0
0
6
42
1.44
0.35
1.7
2.2
2.40
4.67
umol/l
—
6
30
6
88
0.68
0.33
1.3
1.4
—
—
—
0
0
24
281
0.84
0.30
25.6
7.2
—
—
—
0
0
80
743
1.10
0.29
5.2
4.4
24.43
21.36
%
0.85
45
349
11
85
1.30
0.28
1.4
1.2
—
—
—
0
0
11
85
1.30
0.28
1.4
1.2
—
—
—
0
0
22
187
1.19
0.27
2.0
2.4
—
11.90
—
0
11
35
391
0.88
0.25
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
8.84
—
0
10
0
12
0.00
0.21
0.0
1.6
—
64.38
—
0
12
5
43
1.17
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.3
1.5
—
—
—
0
0
6
52
1.16
0.19
1.3
1.6
—
—
—
0
0
8
69
1.16
0.16
1.8
1.5
—
—
—
0
0
11
127
0.86
0.12
1.3
1.0
—
—
—
0
0
7
67
1.05
0.08
1.4
1.7
197.29
227.48
pmol/l
—
7
61
34
323
1.06
0.08
1.8
2.0
—
—
—
0
0
8
78
1.03
0.07
1.7
1.6
—
—
—
0
0
8
78
1.03
0.07
1.9
1.5
—
—
—
0
0
37
357
1.04
0.05
1.8
2.1
—
—
—
0
0
16
150
1.07
0.04
1.3
1.3
—
—
—
0
0
20
190
1.06
0.04
1.2
1.3
177.16
143.52
iu/ml
—
10
72
14
148
0.94
0.02
1.8
1.5
—
—
—
0
0
27
264
1.02
0.00
1.4
1.7
—
—
—
0
0
55
544
1.01
0.00
3.5
3.1
1.59
0.83
ug/l
0.47
40
360
8
82
0.97
-0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
14.96
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.97
-0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
82
0.97
-0.00
1.8
1.5
—
—
—
0
0
8
88
0.91
-0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
82
0.97
-0.00
1.8
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RECURANDPERHEAMATUR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RECURANDPERHEAMATUR | 2.32 [1.83, 2.94] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.11 |
During the follow-up period (1.1.1998 — 31.12.2019), 187 out of 1005 females with N14_RECURANDPERHEAMATUR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RECURANDPERHEAMATUR | 2.256 [1.73, 2.94] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 422 out of 1118 males with N14_RECURANDPERHEAMATUR died.
Mortality risk
Mortality risk for people of age
years, who have N14_RECURANDPERHEAMATUR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.347% |
| 5 | 1.295% | 2.358% |
| 10 | 3.217% | 5.811% |
| 15 | 5.868% | 11.113% |
| 20 | 10.82% | 18.533% |
Relationships between endpoints
↥Index endpoint: N14_RECURANDPERHEAMATUR – Recurrent and persistent haematuria
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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