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Renal agenesis and other reduction defects of kidney

Q17_RENAL_AGENE_OTHER_REDUCT_DEFECTS_KIDNEY_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 Q60
  • Hospital discharge: ICD-10 Q60
  • Cause of death: ICD-10 Q60

3 out of 7 registries used, show all original rules.

202

4. Check minimum number of events

None

202

5. Include endpoints

None

202

6. Filter based on genotype QC (FinnGen only)

188

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_URINARY_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q6[0-4]
Name in latin
Agenesis/aplasia/hypoplasia/atrophia renis/renum

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 188 83 105
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 45.70 40.13 50.11

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
202
Matched controls
2020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
+∞
136.4
115
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
78.3
123.2
68
13
A11CC03
ATC
alfacalcidol; systemic
68.4
109.9
62
13
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
33.0
107.7
77
37
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
59.5
91.8
53
12
N18.8
ICD-10 Finland
Other chronic renal failure
39.0
74.8
48
16
L04AA06
ATC
mycophenolic acid; systemic
46.6
72.4
44
12
Q60.3
ICD-10 Finland
Renal hypoplasia, unilateral
+∞
55.9
51
*
Z94.0
ICD-10 Finland
Kidney transplant status
135.6
49.4
51
5
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
14.1
47.9
49
45
A12AA04
ATC
calcium carbonate; oral
77.1
47.1
52
9
127
Kela drug reimbursment
Transplant complication
69.3
42.7
48
9
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
120.1
37.2
39
*
205
Kela drug reimbursment
Chronic hypertension
6.1
35.4
91
239
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
210.3
34.9
35
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
87.0
33.1
36
5
137
Kela drug reimbursment
Uraemia requiring dialysis
72.5
32.3
36
6
N19
ICD-10 Finland
Unspecified kidney failure
13.9
31.5
31
26
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.1
30.5
47
73
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
75.5
28.9
32
5
TK800
NOMESCO Finland
Hemodialysis
34.5
28.8
37
13
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
12.4
28.5
30
28
N18.0
ICD-10 Finland
End-stage renal disease
161.6
27.4
28
*
H02AB04
ATC
methylprednisolone; systemic
5.8
27.1
62
143
KA1AE
NOMESCO Finland
Kidney ultrasound examination
36.8
26.9
34
11
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
67.3
25.8
29
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.3
25.6
67
173
L04AD02
ATC
tacrolimus; systemic
103.4
25.3
27
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
56.0
25.0
29
6
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
141.8
24.2
25
*
B03XA02
ATC
darbepoetin alfa; parenteral
38.8
24.1
30
9
M04AA01
ATC
allopurinol; systemic
5.5
23.5
55
128
Q60.2
ICD-10 Finland
Renal agenesis, unspecified
+∞
23.4
22
*
Q60.4
ICD-10 Finland
Renal hypoplasia, bilateral
+∞
22.3
21
*
L04AD01
ATC
ciclosporin; systemic
24.1
22.1
31
15
B05DA
ATC
Isotonic solutions
56.7
21.7
25
5
Z49.0
ICD-10 Finland
Preparatory care for dialysis
64.4
20.4
23
*
C08CA02
ATC
felodipine; oral
6.5
19.9
36
65
C03CA01
ATC
furosemide; systemic
3.9
19.5
83
304
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
58.2
18.3
21
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.2
18.1
29
46
ZXE20
NOMESCO Finland
More than three and less than five hours
4.6
18.1
52
142
196
Kela drug reimbursment
Paricalcitol and cinacalcet
196.5
17.8
18
*
B05DB
ATC
Hypertonic solutions
46.6
17.7
21
5
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.4
17.6
32
58
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.6
17.2
30
52
N26
ICD-10 Finland
Unspecified contracted kidney
+∞
16.9
16
*
L04AA01
ATC
[U] ciclosporin
44.2
16.7
20
5
Z49.2
ICD-10 Finland
Other dialysis
44.2
16.7
20
5
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
52.1
16.3
19
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
65.5
16.0
18
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.4
15.3
45
124
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
+∞
14.8
14
*
H05BX01
ATC
cinacalcet; oral
161.2
14.7
15
*
C07AB02
ATC
metoprolol; systemic
3.8
14.1
52
168
TK820
NOMESCO Finland
Peritoneal dialysis
57.6
14.0
16
*
C08CA01
ATC
amlodipine; oral
3.1
13.9
90
414
Q60.5
ICD-10 Finland
Renal hypoplasia, unspecified
+∞
13.7
13
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
43.2
13.4
16
*
UKC02
NOMESCO Finland
Cystoscopy
3.9
13.3
45
137
V03AE02
ATC
sevelamer; oral
53.7
13.0
15
*
R50.9
ICD-10 Finland
Fever, unspecified
3.5
13.0
57
206
M10.9
ICD-10 Finland
Gout, unspecified
5.3
12.8
28
60
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
34.5
12.8
16
5
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
74.7
12.8
14
*
RD210, ,
NOMESCO Finland
6.8
12.7
21
34
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
12.5
94
463
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
6.2
12.2
22
39
B03XA01
ATC
erythropoietin; parenteral
24.7
11.8
16
7
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
69.1
11.7
13
*
C09AA02
ATC
enalapril; systemic
3.4
11.7
52
189
204
Kela drug reimbursment
Leukemia lymphatica
13.0
11.1
19
16
U14
ICPC
Kidney symptom/complaint
16.7
11.0
17
11
V03AE01
ATC
polystyrene sulfonate; oral
29.9
10.9
14
5
Z2446
NOMESCO Finland
Social worker
3.8
10.7
36
108
75301
ICD-8 Finland
Congenital anomalies of urinary system, Agenesis renis unilateralis
+∞
10.5
10
*
7530A
ICD-9 Finland
Congenital anomalies of urinary system, Renal agenesis and dysgenesis[AGENESIA RENIS]
+∞
10.5
10
*
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
+∞
10.5
10
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
10.4
48
177
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
10.3
35
106
C08CA05
ATC
nifedipine; systemic
5.2
10.3
22
46
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
42.3
10.1
12
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
9.8
29
79
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.4
9.8
40
137
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
9.7
73
351
N18
ICD-10 Finland
Chronic kidney disease
31.7
9.5
12
*
V03AE03
ATC
lanthanum carbonate; oral
104.7
9.5
10
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
104.7
9.5
10
*
Q62.7
ICD-10 Finland
Congenital vesico-uretero-renal reflux
+∞
9.4
9
*
Q62.0
ICD-10 Finland
Congenital hydronephrosis
+∞
9.4
9
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
9.4
9
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
12.3
9.2
16
14
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.8
9.2
30
88
L04AX01
ATC
azathioprine; systemic
7.4
9.1
21
31
XPX08
NOMESCO Finland
Intraoperative flow measurement
52.3
8.8
10
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
8.7
70
345
XF602
NOMESCO Finland
Bloodpressure monitoring
17.2
8.7
13
8
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
8.6
91
510
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
93.8
8.5
9
*
A02BC01
ATC
omeprazole; systemic
2.6
8.5
61
285
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
8.4
57
258
Q61.48
ICD-10 Finland
Nonspecified renal dysplasia
+∞
8.4
8
*
75302
ICD-8 Finland
Congenital anomalies of urinary system, Hypoplasia et dysplasia renis
+∞
8.4
8
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
8.1
8.4
18
24
K06.18
ICD-10 Finland
Another gingival hyperplasia
34.9
8.2
10
*
3AC01, ,
NOMESCO Finland
23.1
8.1
11
5
J01EA01
ATC
trimethoprim; systemic
2.7
8.1
55
249
Z3231
NOMESCO Finland
Registered nurse
2.4
8.0
77
410
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.0
7.9
15
16
C08CA13
ATC
lercanidipine; oral
3.2
7.9
35
125
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.8
7.8
18
40
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
46.8
7.8
9
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
7.5
80
445
A12AA12
ATC
[U] calcium acetate
83.0
7.5
8
*
KH1EE
NOMESCO Finland
Urologic ultrasound examination
83.0
7.5
8
*
Q60.1
ICD-10 Finland
Renal agenesis, bilateral
+∞
7.3
7
*
Q61.40
ICD-10 Finland
Renal dysplasia of a kidney (multicystic)
+∞
7.3
7
*
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
+∞
7.3
7
*
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
+∞
7.3
7
*
Q60
ICD-10 Finland
Renal agenesis and other reduction defects of kidney
+∞
7.3
7
*
RJ421, ,
NOMESCO Finland
+∞
7.3
7
*
K65.0
ICD-10 Finland
Acute peritonitis
16.5
7.3
11
7
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.0
7.3
17
26
R4110
NOMESCO Finland
Physiotherapy
2.3
7.2
70
373
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
10.6
7.1
13
13
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.5
6.9
17
40
ZXE00
NOMESCO Finland
One hour or less
2.2
6.9
93
566
Z99.2
ICD-10 Finland
Dependence on renal dialysis
41.5
6.8
8
*
KAC00
NOMESCO Finland
Nephrectomy
41.5
6.8
8
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
41.5
6.8
8
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
6.7
28
96
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
23.4
6.7
9
*
E87.5
ICD-10 Finland
Hyperkalaemia
12.8
6.7
11
9
C09CA01
ATC
losartan; oral
2.4
6.7
53
257
Z3226
NOMESCO Finland
Physiotherapist
2.4
6.7
53
257
M10.0
ICD-10 Finland
Idiopathic gout
7.3
6.7
15
22
5AB14, ,
NOMESCO Finland
72.0
6.5
7
*
N13.7
ICD-10 Finland
Vesicoureteral-reflux-associated uropathy
72.0
6.5
7
*
N25.0
ICD-10 Finland
Renal osteodystrophy
72.0
6.5
7
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
11.5
6.4
11
10
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
6.3
51
248
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
18.7
6.3
9
5
C07AG02
ATC
carvedilol; oral
4.2
6.3
17
43
RJ410, ,
NOMESCO Finland
+∞
6.3
6
*
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
+∞
6.3
6
*
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
+∞
6.3
6
*
H05BX02
ATC
paricalcitol; systemic
+∞
6.3
6
*
RJ190, ,
NOMESCO Finland
+∞
6.3
6
*
7910X
ICD-9 Finland
Nonspecific findings on examination of urine, Proteinuria[PROTEINURIA NUD]
+∞
6.3
6
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
+∞
6.3
6
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
27.6
6.3
8
*
C02DE10, ,
ATC
27.6
6.3
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
112
11.64
61.85
9.7
4.1
127.49
67.42
ng/l
3.83
75
103
120
436
5.32
31.14
16.8
3.7
7.38
7.41
ph
4.05
31
81
113
395
5.22
30.66
8.8
3.8
34.14
12.52
mg/mmol
1.85
89
246
109
371
5.21
30.54
7.5
3.2
171.94
255.54
mg/l
0.20
90
234
120
448
5.14
29.78
7.2
3.4
6.72
7.74
mmol/l
1.81
108
378
102
348
4.90
28.03
9.1
2.7
4.68
4.72
e6/l
0.01
94
309
71
195
5.07
25.20
8.5
2.3
23.58
22.01
%
0.44
64
176
94
337
4.35
23.42
8.4
2.9
499.33
553.89
mosm/kgh2o
1.70
83
284
64
176
4.86
22.42
11.4
8.8
—
—
—
0
0
116
513
3.96
20.90
10.4
3.3
96.11
39.62
e6/l
0.44
108
398
32
49
7.57
20.69
2.0
1.5
—
—
—
0
0
105
451
3.77
19.41
9.7
2.9
—
—
—
0
0
64
198
4.27
18.96
10.6
8.6
0.50
1.23
mmol/l
0.90
55
153
53
145
4.60
18.39
9.6
10.1
22.65
23.45
mmol/l
1.39
53
145
126
634
3.62
17.77
4.2
2.4
73.74
73.19
nmol/l
0.08
118
567
89
361
3.62
17.63
6.2
3.5
4724.86
3017.89
umol/l
0.14
84
311
104
467
3.53
17.53
10.0
3.0
0.20
0.22
e6/l
0.11
96
358
121
598
3.55
17.47
11.7
3.7
32.77
101.14
e6/l
0.83
109
422
135
720
3.64
17.14
21.0
8.9
1.23
1.22
mmol/l
1.43
128
669
141
778
3.69
16.85
21.8
9.4
1.22
1.22
mmol/l
0.35
126
672
29
50
6.60
16.71
1.4
1.4
223.57
180.90
u/ml
0.39
21
21
26
40
7.31
16.63
10.5
3.1
—
—
—
0
0
124
640
3.43
16.34
6.0
3.3
6.42
5.95
ph
—
6
66
141
791
3.59
16.13
7.9
3.5
0.00
0.00
estimate
-0.00
36
171
139
800
3.36
14.69
8.0
3.5
0.00
0.00
estimate
-0.00
32
157
68
260
3.44
14.34
4.8
3.1
2.04
1.88
e6/l
0.07
49
156
137
790
3.28
14.26
9.7
4.7
0.00
0.00
estimate
-0.00
36
165
123
670
3.14
14.09
11.0
5.9
35.26
35.91
g/l
0.61
118
632
26
26
11.30
13.96
12.8
3.2
—
—
—
0
0
40
113
4.17
13.06
14.8
3.9
1.21
1.23
mmol/l
0.62
35
97
16
5
34.53
12.77
2.2
3.4
—
—
—
0
0
29
67
4.89
12.15
4.1
6.2
0.25
0.41
g/l
0.43
23
34
80
367
2.95
12.07
5.6
3.3
—
—
—
0
0
87
430
2.80
11.28
3.6
2.7
—
—
—
0
0
162
1106
3.35
11.26
10.4
4.0
—
—
—
0
0
42
139
3.55
10.85
2.0
3.8
61.82
68.39
e9/l
0.55
25
109
21
40
5.74
10.84
10.6
3.0
2.87
2.61
mmol/l
—
9
28
18
15
13.04
10.58
1.0
1.7
—
—
—
0
0
19
18
11.52
10.53
1.9
3.4
—
—
—
0
0
21
45
5.09
9.53
11.4
3.0
7.38
7.43
ph
5.17
21
40
30
92
3.66
8.61
1.6
1.4
—
—
—
0
0
17
20
9.17
8.49
1.4
5.3
—
—
—
0
0
27
78
3.84
8.43
6.3
10.7
0.67
0.64
%
0.18
27
78
81
434
2.45
8.41
10.0
3.7
0.00
0.00
estimate
-0.00
28
159
20
32
6.82
8.26
7.4
8.4
—
—
—
0
0
16
18
9.55
8.21
3.4
3.0
1.88
2.82
g/24h
—
10
11
11
5
23.13
8.10
2.7
1.6
—
—
—
0
0
18
39
4.97
8.05
5.3
20.9
—
—
—
0
0
20
48
4.51
7.94
6.4
11.8
21.26
23.97
mmol/l
2.55
20
48
27
83
3.60
7.70
1.6
2.9
—
—
—
0
0
43
179
2.78
7.40
7.3
10.5
104.28
104.18
mmol/l
0.05
43
179
110
707
2.22
7.16
6.9
2.7
169.94
102.19
ug/l
2.81
104
654
18
31
6.27
7.10
1.4
4.2
53.95
32.00
mg/l
—
10
24
18
31
6.27
7.10
1.4
4.2
78.99
271.13
mg/l
0.44
11
24
143
1026
2.35
7.07
10.1
4.0
19.67
50.69
e6/l
—
6
16
87
513
2.22
6.96
6.9
3.5
2.40
2.36
mmol/l
1.53
81
461
17
40
4.55
6.90
4.5
2.2
124.00
130.97
g/l
0.48
17
30
19
49
4.18
6.88
3.6
3.0
—
—
—
0
0
73
402
2.28
6.88
7.8
4.4
—
—
—
0
0
47
219
2.49
6.41
2.6
2.3
—
—
—
0
0
41
179
2.62
6.39
8.2
8.8
7.38
7.41
ph
0.63
13
12
155
1213
2.19
5.32
13.0
7.1
95.94
88.50
u/l
0.74
148
1134
74
448
2.03
5.24
8.4
3.2
—
—
—
0
0
5
0
+∞
5.23
1.0
0.0
—
—
—
0
0
39
188
2.33
4.87
2.1
1.8
—
—
—
0
0
114
817
1.91
4.80
18.1
10.7
0.00
0.02
e9/l
0.48
92
668
14
31
4.77
4.65
4.3
2.5
4.40
4.94
e9/l
0.29
14
31
14
31
4.77
4.65
4.9
2.7
58.29
57.23
%
0.10
14
31
96
656
1.88
4.64
18.5
11.8
1.19
1.25
inr
0.24
34
206
45
236
2.17
4.59
3.5
1.6
—
—
—
0
0
54
304
2.06
4.59
3.2
1.6
—
—
—
0
0
116
849
1.86
4.45
9.4
7.6
—
—
—
0
0
121
899
1.86
4.41
8.3
6.9
0.04
0.04
e9/l
0.84
108
788
120
897
1.83
4.21
8.4
6.9
0.60
0.59
e9/l
0.26
107
784
11
21
5.47
4.20
1.0
1.8
—
—
—
0
0
123
927
1.84
4.19
8.3
7.0
1.81
2.08
e9/l
2.24
110
834
59
353
1.95
4.19
7.6
3.5
1.02
1.02
kg/l
—
8
46
28
126
2.42
4.06
5.2
5.8
0.00
0.08
%
1.08
11
39
28
126
2.42
4.06
5.2
5.8
0.00
0.13
%
1.24
11
39
62
381
1.91
4.05
3.3
2.0
—
—
—
0
0
26
113
2.49
4.05
7.7
3.5
—
—
—
0
0
29
135
2.34
3.90
1.7
1.4
—
—
—
0
0
121
922
1.78
3.84
8.5
7.5
0.18
0.20
e9/l
0.79
107
827
13
34
4.01
3.77
1.0
1.2
—
—
—
0
0
12
30
4.19
3.66
1.8
1.2
—
—
—
0
0
7
9
8.01
3.58
1.0
1.1
1258.29
1676.44
miu/ml
—
7
9
73
489
1.77
3.56
3.3
2.7
—
—
—
0
0
61
394
1.79
3.33
2.8
2.5
2.88
2.94
mg/l
0.10
50
339
79
550
1.72
3.32
2.1
1.8
99.15
94.84
pmol/l
0.36
43
297
28
138
2.19
3.30
5.2
5.5
0.45
0.98
%
1.07
11
52
166
1422
1.94
3.26
5.6
3.8
1.46
1.29
mmol/l
1.72
156
1318
29
146
2.15
3.25
7.1
9.0
—
—
—
0
0
43
252
1.90
3.19
1.9
1.6
1360.91
1229.45
nmol/l
0.42
35
188
53
334
1.80
3.12
1.9
1.5
22.72
21.25
nmol/l
0.21
47
289
29
149
2.10
3.09
13.2
3.3
—
—
—
0
0
28
142
2.13
3.08
2.1
1.6
—
—
—
0
0
129
1036
1.68
3.07
9.6
10.4
4.22
3.96
e9/l
0.70
114
914
6
8
7.68
3.07
1.0
1.4
—
—
—
0
0
6
8
7.68
3.07
1.0
1.0
—
—
—
0
0
5
5
10.21
2.99
2.8
2.2
—
—
—
0
0
15
59
2.67
2.86
10.2
4.3
—
—
—
0
0
15
60
2.62
2.77
1.7
1.7
—
—
—
0
0
120
963
1.61
2.72
9.6
6.1
6.61
6.48
mmol/l
0.25
114
897
7
15
4.79
2.62
1.3
3.4
—
—
—
0
0
8
20
4.12
2.59
3.1
33.2
12.79
10.93
%
—
8
20
24
126
2.03
2.43
5.3
5.2
0.57
0.36
%
—
7
43
6
13
4.72
2.29
1.2
1.2
—
—
—
0
0
166
1473
1.71
2.25
6.2
4.1
1.41
1.43
mmol/l
0.25
157
1361
32
191
1.80
2.23
1.3
1.2
—
—
—
0
0
20
102
2.07
2.19
1.8
1.3
—
—
—
0
0
7
19
3.78
2.17
1.4
1.4
—
—
—
0
0
7
175
0.38
2.16
1.1
1.3
—
—
—
0
0
8
25
3.29
2.12
1.0
1.5
—
—
—
0
0
166
1481
1.68
2.10
6.2
4.2
4.39
4.59
mmol/l
1.84
158
1379
183
1691
1.87
1.86
29.8
13.5
21.62
22.43
mg/l
0.13
154
1300
14
67
2.17
1.80
6.0
17.1
—
—
—
0
0
167
1512
1.60
1.76
6.4
4.6
2.51
2.74
mmol/l
2.95
157
1393
25
151
1.75
1.69
2.2
3.4
8.49
9.81
g/l
1.01
25
141
155
1386
1.51
1.68
8.2
5.2
38.82
39.41
mmol/mol
0.37
148
1301
38
259
1.58
1.64
2.4
2.9
2.48
2.44
mmol/l
1.01
31
225
5
14
3.63
1.62
1.6
1.1
421.40
878.43
pmol/l
—
5
14
6
20
3.06
1.59
2.7
2.1
—
—
—
0
0
63
483
1.44
1.56
7.5
7.1
—
—
—
0
0
120
1031
1.40
1.55
4.4
3.5
—
—
—
0
0
12
58
2.14
1.52
1.1
1.2
—
—
—
0
0
5
16
3.18
1.44
1.4
1.8
—
—
—
0
0
184
1726
1.74
1.44
29.2
12.2
—
—
—
0
0
54
409
1.44
1.42
1.8
1.8
1.58
1.36
mmol/l
0.78
48
355
70
557
1.39
1.39
3.2
3.6
46.95
37.61
ng/l
0.31
54
371
24
152
1.66
1.39
6.1
11.1
0.97
1.10
mmol/l
0.03
18
119
9
43
2.14
1.32
4.9
2.8
—
—
—
0
0
22
141
1.63
1.23
6.2
11.6
91.69
95.10
%
0.63
22
136
28
191
1.54
1.22
1.4
1.2
—
—
—
0
0
5
19
2.67
1.22
1.0
1.6
—
—
nmol/l
—
0
0
24
159
1.58
1.18
1.3
1.4
—
—
—
0
0
39
289
1.43
1.15
2.2
1.8
376.97
16393901.81
pmol/l
0.50
34
244
5
22
2.30
1.04
1.4
1.1
—
—
—
0
0
59
477
1.33
1.04
1.5
1.5
—
—
—
0
0
9
48
1.92
1.02
14.6
16.7
—
—
—
0
0
11
61
1.85
1.00
1.5
1.2
—
—
—
0
0
15
92
1.68
1.00
6.9
9.3
—
—
—
0
0
12
69
1.79
0.99
2.8
1.9
—
—
—
0
0
5
23
2.20
0.98
1.2
1.0
—
—
—
0
0
6
28
2.18
0.92
1.0
1.0
—
—
—
0
0
6
28
2.18
0.92
1.0
1.0
—
—
—
0
0
5
103
0.47
0.92
1.8
1.6
—
—
—
0
0
11
63
1.79
0.92
3.9
11.3
24.32
24.04
mmol/l
0.06
11
63
5
104
0.47
0.92
1.8
1.6
—
—
—
0
0
5
104
0.47
0.92
1.8
1.6
—
—
—
0
0
5
104
0.47
0.92
1.8
1.6
—
—
—
0
0
29
214
1.41
0.89
2.0
1.8
—
—
—
0
0
10
166
0.58
0.88
1.2
1.5
—
—
—
0
0
45
360
1.32
0.85
1.7
2.5
0.95
1.40
mg/l
1.04
36
283
13
81
1.65
0.83
3.5
3.8
—
—
—
0
0
5
98
0.50
0.80
1.8
1.6
—
—
—
0
0
9
55
1.67
0.74
1.3
1.7
—
—
—
0
0
13
84
1.59
0.74
1.2
1.3
—
29.97
—
0
6
20
143
1.44
0.73
4.1
5.1
4.06
38.77
ug/l
0.58
15
113
7
39
1.82
0.73
1.9
2.1
—
—
—
0
0
24
178
1.40
0.73
1.5
1.6
—
—
—
0
0
23
304
0.73
0.71
3.0
2.9
0.63
0.74
ug/l
0.41
15
188
21
153
1.42
0.70
1.5
1.6
—
—
—
0
0
14
95
1.51
0.66
2.2
2.4
—
16.48
—
0
6
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
128
1191
1.20
0.60
5.3
3.9
16.66
10.81
mm/h
2.28
121
1098
7
115
0.59
0.59
1.0
1.4
—
—
—
0
0
10
66
1.54
0.53
1.3
1.5
115.30
275.81
miu/ml
—
5
34
7
46
1.54
0.49
1.9
1.3
—
—
—
0
0
63
564
1.17
0.44
4.0
2.7
—
—
—
0
0
5
31
1.63
0.43
4.2
4.9
—
—
—
0
0
5
31
1.63
0.43
2.4
3.7
5.76
7.16
mmol/l
—
5
31
32
269
1.23
0.43
3.6
2.9
1323.00
212.04
ng/l
0.69
25
191
0
15
0.00
0.41
0.0
1.1
—
292.67
—
0
15
0
15
0.00
0.41
0.0
1.9
—
2.53
—
0
15
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
230.29
—
0
17
0
17
0.00
0.41
0.0
11.8
—
629.35
—
0
17
16
124
1.32
0.40
9.8
5.2
—
—
—
0
0
21
254
0.81
0.36
1.5
1.6
—
—
—
0
0
5
80
0.62
0.36
1.6
1.6
—
—
—
0
0
6
44
1.37
0.34
1.7
3.5
—
—
—
0
0
24
202
1.21
0.33
3.2
4.2
4.89
9.25
umol/l
1.30
19
174
12
92
1.32
0.32
1.6
2.6
623.33
167.45
ng/l
0.90
12
80
7
52
1.36
0.31
1.9
2.0
176.14
226.85
pmol/l
—
7
46
12
93
1.31
0.30
1.4
1.2
—
—
—
0
0
13
162
0.79
0.29
3.2
2.5
15.18
12.97
nmol/l
0.50
13
147
14
112
1.27
0.29
1.5
1.4
178.05
437.88
u/ml
0.55
14
99
9
77
1.18
0.24
1.2
1.1
—
—
—
0
0
26
228
1.16
0.24
1.3
1.2
10.40
35.15
iu/ml
—
6
67
44
403
1.12
0.22
3.5
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
1.56
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
3.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
1.13
—
0
12
0
12
0.00
0.21
0.0
1.2
—
5.52
—
0
12
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
245.00
—
0
7
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
12
99
1.23
0.20
2.7
2.2
—
—
—
0
0
47
438
1.10
0.18
1.5
1.5
2.17
2.10
g/l
0.08
29
246
144
1472
0.92
0.16
4.4
4.2
2.10
1.95
mu/l
0.31
134
1339
189
1871
1.16
0.14
41.2
19.9
244.40
252.40
e9/l
0.98
184
1821
189
1872
1.15
0.13
41.3
20.1
39.12
40.51
%
2.93
180
1785
189
1873
1.14
0.12
41.1
19.9
4.41
4.56
e12/l
2.23
182
1819
44
464
0.93
0.11
1.4
1.4
0.64
1.10
u/ml
1.02
13
103
27
250
1.09
0.11
2.4
2.9
89.32
131.81
ug/g
0.83
22
199
144
1465
0.94
0.11
6.2
4.2
5.81
5.89
mmol/l
0.38
132
1332
12
105
1.15
0.11
1.1
1.3
23.73
103.82
iu/ml
—
6
38
189
1874
1.13
0.11
41.2
19.9
6.96
6.80
e9/l
0.52
182
1821
59
568
1.05
0.09
2.5
2.1
—
—
—
0
0
10
113
0.88
0.08
2.4
3.2
3.34
6.43
e9/l
—
10
98
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
7
67
1.05
0.08
2.0
1.9
—
—
—
0
0
175
1735
1.06
0.07
17.5
10.2
51.39
27.21
u/l
0.42
170
1672
50
515
0.96
0.05
4.1
4.9
2.27
2.58
ug/l
0.12
44
458
121
1196
1.03
0.04
3.8
3.6
14.84
14.72
pmol/l
0.21
115
1081
12
111
1.09
0.04
1.2
1.4
—
—
—
0
0
23
224
1.03
0.00
1.4
1.3
2.03
7.49
u/ml
—
6
82
17
168
1.01
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
129.00
—
0
7
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
5.49
—
0
7
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
61.57
—
0
7
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
8.75
—
0
7
5
52
0.96
-0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
11426.60
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
170.40
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
3.63
—
0
6
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
57
0.87
-0.00
2.0
3.9
11.20
430.32
u/ml
—
5
50
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
97.80
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
19.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
27.11
—
0
6
0
5
0.00
-0.00
0.0
5.0
—
4.54
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.34
—
0
5
0
6
0.00
-0.00
0.0
3.8
—
18.37
—
0
6
0
8
0.00
-0.00
0.0
29.0
—
0.62
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
0.99
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_RENAL_AGENE_OTHER_REDUCT_DEFECTS_KIDNEY_WIDE – Renal agenesis and other reduction defects of kidney

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).