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Absence of one kidney

Endpoint Browser PheWeb

Q17_ABSENCE_OF_ONE_KIDNEY

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q60.0
  • Cause of death: ICD-10 — Q60.0

2 out of 7 registries used, show all original rules.

96

4. Check minimum number of events

None

96

5. Include endpoints

None

96

6. Filter based on genotype QC (FinnGen only)

86

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 86 43 43
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 48.53 36.85 60.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
96
Matched controls
960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
+∞
138.3
96
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
44.9
20.0
24
7
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
20.2
19.8
30
21
A11CC03
ATC
alfacalcidol; systemic
49.6
19.6
23
6
Z94.0
ICD-10 Finland
Kidney transplant status
58.5
13.3
15
*
UKC02
NOMESCO Finland
Cystoscopy
5.9
12.7
28
63
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
31.6
12.5
16
6
A12AA04
ATC
calcium carbonate; oral
31.6
12.5
16
6
205
Kela drug reimbursment
Chronic hypertension
4.8
12.1
38
115
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
135.6
11.7
12
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
40.4
11.6
14
*
N18.8
ICD-10 Finland
Other chronic renal failure
18.5
11.3
17
11
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
11.7
10.9
20
21
127
Kela drug reimbursment
Transplant complication
27.0
10.6
14
6
137
Kela drug reimbursment
Uraemia requiring dialysis
45.1
10.2
12
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
45.1
10.2
12
*
N19
ICD-10 Finland
Unspecified kidney failure
14.5
9.8
16
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.7
9.4
26
70
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
40.9
9.2
11
*
L04AD02
ATC
tacrolimus; systemic
55.2
8.9
10
*
B05DA
ATC
Isotonic solutions
98.3
8.6
9
*
7530A
ICD-9 Finland
Congenital anomalies of urinary system, Renal agenesis and dysgenesis[AGENESIA RENIS]
+∞
8.4
8
*
75301
ICD-8 Finland
Congenital anomalies of urinary system, Agenesis renis unilateralis
+∞
8.4
8
*
N18.0
ICD-10 Finland
End-stage renal disease
+∞
8.4
8
*
L04AA06
ATC
mycophenolic acid; systemic
19.3
8.3
12
7
TK800
NOMESCO Finland
Hemodialysis
24.5
8.2
11
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
8.2
28
88
ZXE20
NOMESCO Finland
More than three and less than five hours
4.5
8.0
23
63
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
49.1
7.9
9
*
Q60.3
ICD-10 Finland
Renal hypoplasia, unilateral
+∞
7.4
7
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
15.3
7.1
11
8
Z49.0
ICD-10 Finland
Preparatory care for dialysis
43.2
6.9
8
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
43.2
6.9
8
*
TK820
NOMESCO Finland
Peritoneal dialysis
43.2
6.9
8
*
H02AB04
ATC
methylprednisolone; systemic
4.0
6.6
22
67
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
28.8
6.3
8
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
191
4.76
13.13
8.6
3.8
33.11
12.22
mg/mmol
1.37
41
122
49
178
4.58
12.41
8.0
3.2
192.57
85.62
mg/l
1.17
42
114
54
216
4.43
11.92
17.2
4.0
7.39
7.41
ph
—
10
38
40
160
3.57
8.24
6.3
3.0
541.57
565.29
mosm/kgh2o
0.26
35
134
28
88
4.08
8.19
12.5
11.0
—
—
—
0
0
53
263
3.27
7.56
9.7
3.3
95.86
46.37
e6/l
0.24
47
204
23
68
4.13
7.24
9.3
12.2
22.71
23.35
mmol/l
0.49
23
68
48
232
3.14
7.05
3.2
2.7
—
—
—
0
0
66
385
3.29
6.94
23.3
11.6
1.23
1.22
mmol/l
0.36
59
338
48
236
3.07
6.78
8.0
3.1
—
—
—
0
0
59
326
3.10
6.76
11.0
6.5
35.29
35.97
g/l
0.39
54
307
28
101
3.50
6.60
10.8
9.6
0.43
1.06
mmol/l
0.43
28
78
28
101
3.50
6.60
10.9
9.6
6.01
5.61
kpa
1.69
28
101
68
413
3.22
6.49
6.7
3.6
0.00
0.00
estimate
-0.00
13
96
56
307
2.98
6.40
11.4
4.0
47.43
60.54
e6/l
0.21
48
217
26
93
3.46
6.17
7.7
10.2
4.84
4.83
kpa
0.01
26
93
80
549
3.74
5.95
10.0
4.2
—
—
—
0
0
32
136
3.03
5.69
5.2
3.6
2.45
2.25
e6/l
0.04
22
79
66
418
2.85
5.41
6.9
3.6
0.00
0.00
estimate
-0.00
12
89
65
412
2.79
5.26
8.7
4.9
0.00
0.00
estimate
-0.00
13
91
15
42
4.05
4.99
1.4
3.7
—
—
—
0
0
45
243
2.60
4.97
8.5
3.2
0.37
0.24
e6/l
0.28
39
184
21
82
3.00
4.23
2.0
4.7
67.10
66.45
e9/l
0.02
13
64
8
10
8.60
4.15
1.0
1.7
—
—
—
0
0
29
138
2.58
4.03
4.3
7.0
0.80
0.82
mmol/l
0.51
29
129
12
29
4.58
3.86
2.3
1.6
—
—
—
0
0
8
13
6.60
3.58
2.0
3.2
—
—
—
0
0
9
19
5.11
3.33
6.0
3.8
—
—
—
0
0
21
97
2.49
3.05
9.5
12.6
104.33
104.20
mmol/l
0.07
21
97
7
13
5.71
2.92
1.9
1.2
—
—
—
0
0
6
9
7.02
2.91
1.7
9.9
—
—
—
0
0
8
18
4.75
2.86
9.9
4.0
4.99
5.14
kpa
—
8
18
37
224
2.06
2.82
6.1
3.1
—
—
—
0
0
6
10
6.31
2.74
13.0
3.0
—
—
—
0
0
42
270
1.99
2.69
2.1
1.8
102.55
93.19
pmol/l
0.80
24
154
33
195
2.05
2.66
6.0
3.8
—
—
—
0
0
19
90
2.39
2.60
7.4
16.9
23.41
24.93
mmol/l
1.65
19
90
12
45
2.90
2.56
8.5
11.7
0.64
0.69
%
0.19
12
45
9
26
3.71
2.55
2.2
2.6
—
—
—
0
0
13
52
2.73
2.48
1.5
1.5
—
—
—
0
0
7
18
4.11
2.30
1.0
1.4
—
—
—
0
0
7
18
4.11
2.30
4.7
24.5
75.71
67.35
%
—
7
18
33
207
1.91
2.20
8.1
5.0
—
—
—
0
0
7
20
3.69
2.10
4.9
27.3
—
—
—
0
0
58
439
1.81
2.08
6.9
8.1
0.04
0.04
e9/l
0.04
52
382
6
15
4.19
2.07
3.3
3.3
4.08
4.26
e9/l
—
6
15
6
15
4.19
2.07
3.3
3.3
62.00
57.93
%
—
6
15
12
52
2.49
1.97
8.6
13.2
118.42
125.87
g/l
0.44
12
52
6
16
3.93
1.96
1.8
2.7
1.43
1.59
mmol/l
—
6
16
6
17
3.69
1.87
4.5
2.9
—
—
—
0
0
5
12
4.33
1.84
1.0
1.9
—
—
—
0
0
57
439
1.73
1.84
6.9
8.1
0.60
0.59
e9/l
0.14
51
383
8
29
2.91
1.84
1.9
1.7
—
—
—
0
0
44
316
1.72
1.82
17.4
14.5
1.07
1.23
inr
0.69
12
97
16
82
2.14
1.82
8.7
8.4
—
—
—
0
0
15
75
2.19
1.81
8.2
17.5
1.31
1.05
mmol/l
—
10
60
37
254
1.74
1.79
3.2
3.1
—
—
—
0
0
59
461
1.73
1.79
6.9
8.1
1.90
2.04
e9/l
0.61
52
416
7
24
3.06
1.76
7.0
6.2
22.70
24.70
mmol/l
—
7
24
64
513
1.74
1.76
7.5
12.1
4.32
4.11
e9/l
0.31
55
457
5
13
3.99
1.73
3.2
33.2
11.74
10.47
%
—
5
13
5
13
3.99
1.73
2.2
1.1
—
—
—
0
0
55
424
1.70
1.73
7.6
9.1
—
—
—
0
0
34
231
1.73
1.70
8.8
3.7
0.00
0.00
estimate
—
10
89
8
32
2.63
1.64
16.3
4.7
—
—
—
0
0
89
806
2.43
1.61
28.8
15.4
22.57
22.27
mg/l
0.03
77
632
37
261
1.68
1.60
3.4
4.3
29.88
27.77
ng/l
0.15
27
180
6
21
2.98
1.53
2.0
1.4
—
—
—
0
0
57
453
1.64
1.52
7.1
8.8
0.20
0.19
e9/l
0.31
51
409
7
28
2.61
1.48
1.1
1.3
—
—
—
0
0
13
67
2.09
1.46
8.7
4.1
—
—
—
0
0
9
40
2.38
1.44
12.3
3.9
24.69
24.08
mmol/l
—
9
40
16
91
1.91
1.39
2.9
1.7
—
—
—
0
0
30
207
1.65
1.38
3.4
2.1
—
—
—
0
0
13
69
2.02
1.36
1.8
1.3
—
—
—
0
0
21
132
1.76
1.35
3.7
1.6
—
—
—
0
0
9
44
2.15
1.31
10.3
15.7
—
—
—
0
0
13
72
1.93
1.22
2.7
1.7
—
—
—
0
0
18
112
1.75
1.19
3.2
2.5
—
—
—
0
0
0
35
0.00
1.18
0.0
1.5
—
—
—
0
0
5
21
2.45
1.10
20.0
17.0
—
—
—
0
0
77
686
1.62
1.06
5.3
3.9
1.37
1.24
mmol/l
0.70
72
638
11
61
1.91
1.03
12.8
5.8
—
—
—
0
0
7
35
2.08
1.02
9.1
26.1
—
—
—
0
0
78
704
1.58
0.93
5.8
4.2
1.46
1.44
mmol/l
0.17
73
652
88
822
1.85
0.92
31.4
13.6
—
—
—
0
0
11
64
1.81
0.90
2.2
2.2
1.05
1.13
g/l
0.10
11
59
79
717
1.57
0.90
6.0
4.6
2.52
2.72
mmol/l
1.23
73
661
6
30
2.06
0.88
5.0
17.7
25.92
23.80
mmol/l
—
6
30
48
398
1.41
0.88
17.0
12.5
0.00
0.03
e9/l
0.50
35
321
78
708
1.54
0.86
6.0
4.2
4.43
4.55
mmol/l
0.58
73
662
24
175
1.50
0.86
3.5
1.7
—
—
—
0
0
27
204
1.45
0.81
3.1
2.4
2.91
2.84
mg/l
0.07
21
170
12
76
1.66
0.76
2.8
4.4
8.81
9.00
g/l
0.06
12
71
5
25
2.05
0.74
7.0
2.9
—
—
—
0
0
19
137
1.48
0.72
2.2
2.9
2.50
2.45
mmol/l
2.02
14
120
7
41
1.76
0.71
1.6
1.2
—
—
—
0
0
7
43
1.68
0.68
1.4
2.5
115.00
240.32
ng/l
—
7
38
12
82
1.53
0.57
1.8
1.8
—
—
—
0
0
11
76
1.51
0.50
9.0
3.3
—
—
—
0
0
18
228
0.74
0.48
1.4
1.5
0.58
1.33
u/ml
—
6
50
0
19
0.00
0.39
0.0
4.1
—
—
—
0
0
29
247
1.25
0.39
1.5
1.6
—
—
—
0
0
13
99
1.36
0.38
1.2
1.2
—
—
—
0
0
9
71
1.29
0.37
1.6
1.4
—
—
—
0
0
54
494
1.21
0.37
4.2
3.7
—
—
—
0
0
6
42
1.46
0.36
2.3
3.7
—
—
—
0
0
26
221
1.24
0.36
4.8
8.0
—
—
—
0
0
8
66
1.23
0.27
1.8
1.3
251.75
574.72
u/ml
—
8
61
10
78
1.31
0.25
1.2
1.9
—
—
—
0
0
5
37
1.37
0.24
1.0
1.7
31.26
20.19
iu/l
—
5
29
16
135
1.22
0.23
2.2
2.9
13.40
312.40
ng/l
—
10
95
22
193
1.18
0.22
3.9
4.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
118.19
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
25.67
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
91
893
1.37
0.17
42.1
23.0
38.94
40.23
%
1.45
84
857
11
130
0.83
0.17
1.5
1.7
—
—
—
0
0
22
198
1.14
0.16
1.8
2.9
1.11
1.22
mg/l
0.10
16
165
27
248
1.12
0.15
3.7
2.9
—
—
—
0
0
75
730
1.13
0.13
4.3
4.3
2.34
1.95
mu/l
0.50
70
661
5
47
1.07
0.09
1.6
1.2
—
—
—
0
0
11
97
1.15
0.09
1.2
1.2
—
—
—
0
0
5
64
0.77
0.08
1.0
1.4
—
—
—
0
0
6
73
0.81
0.08
3.2
2.2
15.65
12.06
nmol/l
—
6
68
8
78
1.03
0.07
1.1
1.2
—
—
—
0
0
21
222
0.93
0.06
1.5
1.6
1.69
2.02
g/l
0.88
13
132
13
139
0.93
0.03
2.2
2.8
0.69
0.79
ug/l
—
8
92
13
123
1.07
0.02
1.9
1.8
—
—
—
0
0
29
283
1.04
0.01
2.2
2.1
—
—
—
0
0
5
59
0.84
0.00
1.2
1.2
—
—
—
0
0
5
49
1.02
-0.00
3.4
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
158.00
—
0
7
0
7
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
251.71
—
0
7
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
51
0.98
-0.00
3.0
3.4
3.17
9.41
e9/l
—
5
44
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
10.6
—
417.29
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
31.0
—
0.50
—
0
6
0
5
0.00
-0.00
0.0
10.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
0.92
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
1.60
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
2.03
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
7.69
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
21.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
19.6
—
825.43
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
3.95
—
0
5
0
6
0.00
-0.00
0.0
10.5
—
9.21
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
11.40
—
0
5

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_ABSENCE_OF_ONE_KIDNEY – Absence of one kidney

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).