Pneumonia due to other infectious organisms, not elsewhere classified

J10_PNEUMONONBACT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J16|J17[2-8]
  • Hospital discharge: ICD-9 483
  • Hospital discharge: ICD-8 48399
  • Cause of death: ICD-10 J16|J17[2-8]
  • Cause of death: ICD-9 483
  • Cause of death: ICD-8 48399

2 out of 7 registries used, show all original rules.

1189

4. Check minimum number of events

None

1189

5. Include endpoints

None

1189

6. Filter based on genotype QC (FinnGen only)

1189

Control definitions (FinnGen only)

Control exclude
J10_INFLUPNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9869 4313 5437
Only index persons 7295 3334 3961
Unadjusted period prevalence (%)
Whole population 0.14 0.12 0.15
Only index persons 0.14 0.12 0.15
Median age at first event (years)
Whole population 55.32 52.82 57.02
Only index persons 43.09 42.06 43.96

-FinnGen-

Key figures

All Female Male
Number of individuals 1189 567 622
Unadjusted period prevalence (%) 0.24 0.19 0.27
Median age at first event (years) 56.29 49.76 62.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1058
Matched controls
10578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J18.9
ICD-10 Finland
Pneumonia, unspecified
43.2
323.0
536
245
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
323.0
367
*
TGC00
NOMESCO Finland
Bronchial lavation
42.2
187.5
235
71
J16.8
ICD-10 Finland
Pneumonia due to other specified infectious organisms
1953.9
170.6
161
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
81.9
169.7
189
28
48399
ICD-8 Finland
Pneumonia due to other specified organism
+∞
152.9
143
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
13.5
150.7
280
275
4830A
ICD-9 Finland
Pneumonia due to other specified organism, Mycoplasma pneumoniae[PNEUMONIA E MYCOPLASMA PNEUMONIAE]
+∞
136.5
128
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
16.8
130.0
216
159
R50.9
ICD-10 Finland
Fever, unspecified
6.8
112.4
325
648
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.1
105.1
224
274
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.8
97.1
245
393
H02AB06
ATC
prednisolone; systemic
3.9
93.9
658
3149
J16.0
ICD-10 Finland
Chlamydial pneumonia
+∞
92.0
87
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
12.0
91.7
176
173
4830X
ICD-9 Finland
Pneumonia due to other specified organism, Mycoplasma pneumoniae[PNEUMONIA ALIA DEFINITA]
+∞
76.0
72
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.5
74.6
214
400
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
71.9
582
2876
ZX108
NOMESCO Finland
Inhalation
46.1
62.9
77
18
J01MA14
ATC
moxifloxacin; systemic
6.7
62.3
170
293
XW000
NOMESCO Finland
Bone marrow biopsy
9.5
61.9
133
158
J01MA12
ATC
levofloxacin; systemic
4.0
60.7
287
903
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
13.0
57.9
105
89
WW500
NOMESCO Finland
Blood transfusion
9.2
56.7
124
151
ZX120
NOMESCO Finland
Intravenous
5.2
56.1
192
435
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
8.6
55.7
127
166
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
52.7
247
760
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.7
52.3
110
125
L03AA02
ATC
filgrastim; parenteral
12.0
51.2
96
87
J17.3
ICD-10 Finland
Pneumonia in parasitic diseases
+∞
50.4
48
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.7
49.8
153
303
GD1AD
NOMESCO Finland
Thorax CT examination
9.6
49.7
105
120
JN4BD
NOMESCO Finland
Extensive body CT
4.2
47.7
200
551
JN4AD
NOMESCO Finland
Body CT examination
5.2
46.9
157
343
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
43.0
397
1934
J01FF01
ATC
clindamycin; systemic
2.8
42.5
361
1673
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.7
42.4
113
185
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
13.6
42.1
74
58
A04AA01
ATC
ondansetron; systemic, rectal
5.4
41.7
134
278
C03CA01
ATC
furosemide; systemic
2.7
41.5
356
1655
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
41.2
288
1174
L04AA06
ATC
mycophenolic acid; systemic
15.4
40.8
68
47
H02AB02
ATC
dexamethasone; systemic
4.2
40.0
168
459
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
+∞
39.8
38
*
Z51.5
ICD-10 Finland
Palliative care
6.0
39.5
114
207
D70.82
ICD-10 Finland
Drug-induced neutropenia
15.9
38.4
63
42
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.4
38.3
122
250
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
11.0
37.1
72
70
M04AA01
ATC
allopurinol; systemic
3.3
36.7
206
714
127
Kela drug reimbursment
Transplant complication
16.5
35.9
58
37
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.3
35.7
115
238
L04AX01
ATC
azathioprine; systemic
6.1
35.6
101
179
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
35.0
273
1177
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.9
35.0
82
111
L03AA13
ATC
pegfilgrastim; parenteral
7.3
34.9
87
129
N02AA05
ATC
oxycodone; systemic
3.3
34.7
200
703
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
27.2
34.4
47
18
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.8
34.1
89
141
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
39.7
33.6
42
11
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.6
33.4
165
515
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
33.3
196
699
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
13.3
32.9
58
46
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
32.0
192
692
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
32.0
557
3581
48609
ICD-8 Finland
Pneumonia, unspecified
+∞
31.4
30
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.4
30.5
64
72
R03AC02
ATC
salbutamol; inhalant
2.1
30.4
563
3685
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
12.9
30.3
54
44
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.2
29.5
118
305
A02BC02
ATC
pantoprazole; systemic
2.1
29.3
700
5069
R03BB04
ATC
tiotropium bromide; inhalant
3.9
28.9
127
357
R06.0
ICD-10 Finland
Dyspnoea
2.4
27.6
292
1465
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
27.5
216
921
1CX01
NOMESCO Finland
NA
+∞
27.2
26
*
B59
ICD-10 Finland
Pneumocystosis
+∞
27.2
26
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
11.3
27.0
51
47
R81
ICPC
Pneumonia
10.3
26.7
53
54
L04AD01
ATC
ciclosporin; systemic
9.9
26.7
54
57
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.6
26.7
226
1003
A04AA02
ATC
granisetron; systemic, transdermal
4.1
25.8
106
280
J45.9
ICD-10 Finland
Asthma, unspecified
2.7
25.7
202
858
H02AB07
ATC
prednisone; oral
2.8
24.7
181
735
J05AB11
ATC
valaciclovir; oral
2.8
24.3
173
691
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
29.9
24.2
32
11
J02AC03
ATC
voriconazole; systemic
57.4
24.1
28
5
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
88.8
23.8
26
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
14.3
23.7
40
29
H02AB04
ATC
methylprednisolone; systemic
2.6
22.9
184
789
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
22.3
373
2252
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.9
22.2
74
159
ZX112
NOMESCO Finland
Subcutaneous
7.6
22.2
52
71
A41.9
ICD-10 Finland
Sepsis, unspecified
5.9
22.1
63
113
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.7
21.8
64
119
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
21.6
318
1818
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.2
21.6
121
411
TK800
NOMESCO Finland
Hemodialysis
8.0
21.5
49
64
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
34.6
21.2
27
8
WW300
NOMESCO Finland
Transfer of autologic stem cells
51.1
21.2
25
5
J01FA06
ATC
roxithromycin; oral
1.9
20.9
418
2685
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
13.3
20.8
36
28
L04AA01
ATC
[U] ciclosporin; systemic
10.6
20.7
40
39
Z94.0
ICD-10 Finland
Kidney transplant status
12.8
20.5
36
29
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.3
20.3
63
125
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.8
20.0
46
61
B03XA01
ATC
erythropoietin; parenteral
15.7
19.8
32
21
H02AB09
ATC
hydrocortisone; systemic
7.8
19.5
45
60
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.0
19.2
79
209
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.2
19.2
105
350
A46
ICD-10 Finland
Erysipelas
2.5
18.9
162
714
ZXD05
NOMESCO Finland
Urgent procedure
1.9
18.9
333
2026
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.8
18.8
83
234
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
11.3
18.8
35
32
1XC02
NOMESCO Finland
NA
17.5
18.8
29
17
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
18.6
128
497
J16
ICD-10 Finland
Pneumonia due to other infectious organisms, not elsewhere classified
193.2
18.6
19
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
6.0
18.2
50
86
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
18.1
74
195
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
11.7
18.1
33
29
WX892
NOMESCO Finland
Monitored bed care
3.2
18.0
100
335
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
17.9
107
379
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
17.9
412
2740
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
14.9
17.7
29
20
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.8
17.5
44
67
L03AA14
ATC
lipegfilgrastim; parenteral
6.6
17.5
45
71
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
15.1
17.2
28
19
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
17.2
142
613
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.8
17.0
36
42
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.2
17.0
35
39
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
17.0
241
1339
A03
ICPC
Fever
2.3
16.9
163
761
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
5.7
16.9
49
90
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
16.8
145
641
XG410
NOMESCO Finland
Flow-volume spirometry
4.3
16.7
63
154
J01DB01
ATC
cefalexin; oral
1.9
16.6
835
7040
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.2
16.5
91
305
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.4
16.5
43
69
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
16.5
386
2561
B03XA02
ATC
darbepoetin alfa; parenteral
7.5
16.3
38
52
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
11.4
16.3
30
27
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
6.5
16.2
42
67
A12AA04
ATC
calcium carbonate; oral
8.7
16.0
34
40
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
8.7
16.0
34
40
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.0
16.0
96
341
Z2446
NOMESCO Finland
Social worker
3.3
15.9
84
273
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.2
15.9
61
152
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
15.6
418
2883
J12.8
ICD-10 Finland
Other viral pneumonia
86.4
15.6
17
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
15.4
122
513
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
15.3
76
236
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
15.3
213
1167
N02AX02
ATC
tramadol; systemic, rectal
1.7
15.3
428
2985
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
8.9
15.3
32
37
J96.0
ICD-10 Finland
Acute respiratory failure
13.3
15.2
26
20
N03AX16
ATC
pregabalin; oral
2.0
15.2
240
1380
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
12.0
15.1
27
23
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
8.6
15.0
32
38
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.4
14.8
32
39
M05BX04
ATC
denosumab; parenteral
3.7
14.7
64
179
N02BE01
ATC
paracetamol; systemic, rectal
1.9
14.7
864
7462
A11CC03
ATC
alfacalcidol; systemic
5.8
14.6
41
73
L01BB05
ATC
fludarabine; systemic
+∞
14.6
14
*
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
14.6
14
*
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
+∞
14.6
14
*
390
Kela drug reimbursment
Ibrutinib
81.2
14.6
16
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.4
14.5
130
583
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
152.0
14.5
15
*
P01BA02
ATC
hydroxychloroquine; oral
2.8
14.4
96
365
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
14.4
99
383
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
27.6
14.3
19
7
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
9.9
14.2
28
29
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.6
14.2
24
18
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
6.6
14.2
36
56
B01AB05
ATC
enoxaparin; parenteral
1.8
14.1
306
1960
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.9
14.1
87
315
J05AB01
ATC
aciclovir; systemic
2.0
14.1
220
1255
J01CA04
ATC
amoxicillin; systemic
1.7
14.1
799
6752
XX3DW
NOMESCO Finland
Time consuming IT work
2.4
14.1
120
526
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
14.0
121
531
J47
ICD-10 Finland
Bronchiectasis
8.3
13.8
30
37
J01MA02
ATC
ciprofloxacin; systemic
1.7
13.7
395
2754
WW200
NOMESCO Finland
Immunization
4.9
13.6
44
93
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.8
13.5
87
324
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
13.5
114
497
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.2
13.4
41
81
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
18.5
13.4
20
11
WX002
NOMESCO Finland
Sedation and analgesia
2.0
13.4
202
1138
B01AB10
ATC
tinzaparin; parenteral
2.9
13.3
85
314
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
40.6
13.2
16
*
J01AA02
ATC
doxycycline; systemic
1.7
13.1
775
6541
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
13.0
170
904
JN6AD
NOMESCO Finland
CT of torso and neck
8.0
12.6
28
36
1512
Kela drug reimbursment
Ibrutinib
70.7
12.6
14
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.2
12.5
24
24
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.4
12.5
37
71
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.1
12.5
48
121
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
12.5
117
536
YNB10
NOMESCO Finland
Collection of stem cells for transplant
131.5
12.5
13
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
12.3
280
1810
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
38.0
12.2
15
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
12.1
166
899
N05CF01
ATC
zopiclone; oral
1.7
12.0
306
2042
A06AD11
ATC
lactulose; oral
2.1
11.9
136
683
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.9
11.8
21
18
C90.0
ICD-10 Finland
Multiple myeloma
10.7
11.8
22
21
C83.1
ICD-10 Finland
Mantle cell lymphoma
16.6
11.7
18
11
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.1
11.7
45
114
WX720
NOMESCO Finland
Own respiration
3.5
11.6
54
161
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
11.6
72
263
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.3
11.6
30
49
WX882
NOMESCO Finland
High dependency care
4.4
11.6
41
96
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
11.5
66
228
AA1AD
NOMESCO Finland
CT of head and brain
1.8
11.5
227
1397
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
11.5
90
377
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.5
165
911
J17.2*B44.0
ICD-10 Finland
Pneumonia in invasive aspergillosis
+∞
11.5
11
*
48509
ICD-8 Finland
Bronchopneumonia, unspecified
+∞
11.5
11
*
L01XE27
ATC
[U] ibrutinib; oral
121.3
11.4
12
*
R03BA02
ATC
budesonide; inhalant
1.9
11.4
169
943
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.4
11.3
24
29
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
11.3
264
1710
E0000UV
ATC
NA
1.6
11.3
371
2646
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
35.4
11.3
14
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.9
11.3
45
118
J46
ICD-10 Finland
Status asthmaticus
5.8
11.2
31
55
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.5
11.2
88
370
B02.9
ICD-10 Finland
Zoster without complication
2.8
11.2
71
264
L01AA01
ATC
cyclophosphamide; systemic
25.3
11.2
15
6
R4110
NOMESCO Finland
Physiotherapy
1.7
11.1
259
1679
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.1
11.0
42
106
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
10.9
102
466
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
10.8
67
244
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
10.8
177
1022
137
Kela drug reimbursment
Uraemia requiring dialysis
10.7
10.8
20
19
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
60.6
10.6
12
*
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
60.6
10.6
12
*
ZXE00
NOMESCO Finland
One hour or less
1.6
10.6
389
2841
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
11.4
10.6
19
17
WX725
NOMESCO Finland
Noninvasive ventilation
3.1
10.5
56
186
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
10.4
55
181
A07AA09
ATC
vancomycin; oral
7.8
10.4
23
30
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.9
10.4
41
107
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
32.9
10.3
13
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
8.9
10.3
21
24
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.8
10.3
43
118
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.5
10.3
79
328
WZC30
NOMESCO Finland
Teaching
2.0
10.3
137
734
D69.5
ICD-10 Finland
Secondary thrombocytopenia
23.6
10.3
14
6
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
10.2
56
189
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.3
10.2
37
89
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.1
10.2
31
62
SPAT1255
SPAT
Intravenous administration of medicine
2.6
10.2
76
311
A04AA55
ATC
palonosetron, combinations; systemic
4.0
10.2
40
104
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
10.1
92
416
R53
ICD-10 Finland
Malaise and fatigue
1.8
10.1
188
1131
M01CB01
ATC
sodium aurothiomalate; parenteral
6.2
10.0
26
43
JN4CD
NOMESCO Finland
Very extensive body CT
3.4
10.0
47
142
UJF32
NOMESCO Finland
Coloscopy
1.7
10.0
246
1615
N18.8
ICD-10 Finland
Other chronic renal failure
4.1
9.9
37
92
153
Kela drug reimbursment
Lenalidomid
16.9
9.9
15
9
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.3
9.9
29
56
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
20.2
9.8
14
7
J20
ICD-10 Finland
Acute bronchitis
2.3
9.7
94
437
J96.1
ICD-10 Finland
Chronic respiratory failure
5.9
9.7
26
45
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
13.5
9.7
16
12
Z94.2
ICD-10 Finland
Lung transplant status
55.5
9.7
11
*
N05BA04
ATC
oxazepam; oral
1.7
9.5
233
1522
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
9.5
173
1034
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6.7
9.5
23
35
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
100.9
9.4
10
*
J15.8
ICD-10 Finland
Other bacterial pneumonia
30.3
9.4
12
*
J17.2*B37.1
ICD-10 Finland
Pneumonia in candidiasis
+∞
9.4
9
*
J17.2*B44.1
ICD-10 Finland
Pneumonia in other aspergillosis
+∞
9.4
9
*
RD210
NOMESCO Finland
NA
4.9
9.3
29
60
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.4
9.3
32
74
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.7
9.3
63
245
M05BA04
ATC
alendronic acid; oral
2.4
9.2
79
348
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.3
9.2
45
141
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.8
9.2
37
99
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
6.8
9.2
22
33
TGD00
NOMESCO Finland
Needle biopsy of lung
15.7
9.0
14
9
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.0
208
1333
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
9.0
138
774
WF004
NOMESCO Finland
Palliative radiotherapy
4.6
9.0
30
67
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
9.0
172
1040
J02AC01
ATC
fluconazole; systemic
1.5
8.9
345
2530
TAB00
NOMESCO Finland
Lumbar puncture
2.9
8.9
53
191
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
4.6
8.8
29
64
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.8
8.8
36
98
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.0
8.8
23
39
WX722
NOMESCO Finland
PEEP
3.0
8.7
50
174
L04AA13
ATC
leflunomide; oral
3.8
8.7
35
94
J18
ICD-10 Finland
Pneumonia, organism unspecified
11.7
8.6
15
13
L01AA02
ATC
chlorambucil; oral
16.4
8.6
13
8
L04AX04
ATC
lenalidomide; oral
16.4
8.6
13
8
Z3231
NOMESCO Finland
Registered nurse
1.6
8.5
265
1841
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
27.7
8.5
11
*
6BA02
NOMESCO Finland
NA
27.7
8.5
11
*
R05
ICD-10 Finland
Cough
1.7
8.5
180
1127
ZX131
NOMESCO Finland
Intrathecal
90.7
8.4
9
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
90.7
8.4
9
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
90.7
8.4
9
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
90.7
8.4
9
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
7.9
8.4
18
23
1AA09
NOMESCO Finland
NA
+∞
8.3
8
*
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
8.3
8
*
J17.2
ICD-10 Finland
Pneumonia in mycoses
+∞
8.3
8
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.7
8.3
27
59
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
5.3
8.3
24
46
R28
ICPC
Limited function/disability (R)
8.6
8.3
17
20
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.1
8.3
43
141
A41.8
ICD-10 Finland
Other specified sepsis
5.6
8.3
23
42
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
5.9
8.3
22
38
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.5
8.3
63
259
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.3
358
2681
B05DA
ATC
Isotonic solutions
10.8
8.3
15
14
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
10.8
8.3
15
14
WW409
NOMESCO Finland
Other aferesis
14.6
8.2
13
9
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
4.0
8.2
31
79
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
8.2
88
429
N18.0
ICD-10 Finland
End-stage renal disease
6.1
8.2
21
35
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
8.1
155
938
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
8.1
38
116
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
8.2
8.1
17
21
R06AE07
ATC
cetirizine; oral
1.5
8.1
397
3053
B05DB
ATC
Hypertonic solutions
11.8
8.1
14
12
GD2SN
NOMESCO Finland
Lung ventilation SPECT
10.1
8.0
15
15
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
22.2
8.0
11
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
7.9
314
2301
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.1
7.9
13
10
R03DC03
ATC
montelukast; oral
1.8
7.9
138
814
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.9
118
658
GD1UN
NOMESCO Finland
Lung circulation SPECT
10.9
7.8
14
13
R04.2
ICD-10 Finland
Haemoptysis
3.4
7.8
36
109
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
9.5
7.8
15
16
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.9
7.8
24
50
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.8
130
754
A07AA02
ATC
nystatin; oral
2.4
7.8
63
270
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.1
7.7
23
46
J01FA10
ATC
azithromycin; systemic
1.4
7.7
535
4394
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
45.3
7.7
9
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
45.3
7.7
9
*
A28
ICPC
Limited function/disability NOS
1.8
7.7
129
748
ZY010
NOMESCO Finland
Hospital outpatient
2.7
7.7
50
191
R11
ICD-10 Finland
Nausea and vomiting
2.2
7.6
75
351
R03BA05
ATC
fluticasone; inhalant
1.7
7.6
166
1044
M31.3
ICD-10 Finland
Wegener granulomatosis
18.5
7.6
11
6
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
18.5
7.6
11
6
V03AE02
ATC
sevelamer; oral
11.9
7.6
13
11
R03BA08
ATC
ciclesonide; inhalant
2.1
7.6
82
403
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
7.6
68
308
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
7.6
43
148
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
25.2
7.6
10
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
25.2
7.6
10
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
25.2
7.6
10
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
4.5
7.5
25
57
SPAT1262
SPAT
Handing over of treatment supplies
1.7
7.4
169
1074
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
80.6
7.4
8
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.4
424
3348
V03AE03
ATC
lanthanum carbonate; oral
13.5
7.4
12
9
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.4
7.4
33
98
N06AA09
ATC
amitriptyline; systemic
2.0
7.3
93
488
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.3
590
4964
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
8.4
7.3
15
18
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
6.9
7.3
17
25
B44.9
ICD-10 Finland
Aspergillosis, unspecified
+∞
7.3
7
*
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
7.3
7
*
47099
ICD-8 Finland
Influenza, unqualified
+∞
7.3
7
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.2
7.3
21
41
C07AB07
ATC
bisoprolol; oral
1.4
7.2
431
3424
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
7.2
65
294
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
7.2
50
198
SPAT1263
SPAT
Sampling
1.4
7.2
394
3082
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
30.2
7.2
9
*
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
30.2
7.2
9
*
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
8.0
7.1
15
19
49300
ICD-8 Finland
Asthma, bronchiale
3.9
7.1
27
70
196
Kela drug reimbursment
Paricalcitol and cinacalcet
12.1
7.1
12
10
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.1
170
1099
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.4
7.1
24
56
R4190
NOMESCO Finland
Nutritional therapy
3.2
7.0
35
113
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.7
7.0
46
177
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.5
6.9
52
215
ZXA00
NOMESCO Finland
Right side
1.5
6.9
248
1771
M10.9
ICD-10 Finland
Gout, unspecified
2.2
6.9
66
310
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
6.9
48
191
R03AK08
ATC
formoterol and beclometasone; inhalant
3.0
6.8
36
121
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
8.3
6.8
14
17
R03BA01
ATC
beclometasone; inhalant
1.8
6.8
127
762
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
6.2
6.8
17
28
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
40.3
6.8
8
*
L01EL01
ATC
ibrutinib; oral
40.3
6.8
8
*
RS220
NOMESCO Finland
NA
4.7
6.7
21
45
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.2
6.7
33
106
WW400
NOMESCO Finland
Plasmaferesis
22.7
6.7
9
*
TQW80
NOMESCO Finland
Local dermatologic skincare
3.5
6.6
29
85
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.4
6.6
51
215
ZX100
NOMESCO Finland
Oral
4.6
6.6
21
46
205
Kela drug reimbursment
Chronic hypertension
1.5
6.6
256
1858
S18
ICPC
Laceration/cut
1.4
6.6
391
3087
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
12.3
6.6
11
9
L04AX05
ATC
pirfenidone; oral
12.3
6.6
11
9
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
6.6
58
260
B34.9
ICD-10 Finland
Viral infection, unspecified
3.4
6.6
29
86
E87.5
ICD-10 Finland
Hyperkalaemia
4.8
6.6
20
42
284
Kela drug reimbursment
Nintedanib and pirfenidone
10.1
6.5
12
12
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.3
6.5
31
97
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.5
107
616
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.0
6.5
24
61
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.2
6.5
16
26
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
6.4
72
361
J18.8
ICD-10 Finland
Other pneumonia, organism unspecified
70.3
6.4
7
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
70.3
6.4
7
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
70.3
6.4
7
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
70.3
6.4
7
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.4
6.4
52
225
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.8
6.4
38
138
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
4.1
6.4
23
57
R03DA04
ATC
theophylline; systemic, rectal
2.6
6.4
45
179
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.8
6.4
25
67
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
6.4
51
217
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.6
6.3
15
23
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.3
132
819
N17.8
ICD-10 Finland
Other acute renal failure
6.0
6.3
16
27
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
5.6
6.3
17
31
R03AC03
ATC
terbutaline; inhalant
1.7
6.3
121
735
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
11.1
6.3
11
10
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.9
6.3
24
63
WX110
NOMESCO Finland
Local anesthesy
1.4
6.3
643
5575
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
3.2
6.3
30
95
4809X
ICD-9 Finland
Viral pneumonia, unspecified
+∞
6.3
6
*
J02AC04
ATC
posaconazole; systemic
+∞
6.3
6
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
26.8
6.2
8
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.5
6.2
47
195
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.7
6.2
25
69
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
2.9
6.2
36
129
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
6.2
80
425
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.1
6.1
31
102
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.5
6.1
45
186
R51.80
ICD-10 Finland
Headache
1.7
6.1
121
741
SPAT1301
SPAT
No procedures
1.5
6.1
284
2135
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
6.1
76
400
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
4.9
6.1
18
37
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
6.1
57
263
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
6.0
32
109
R03AC12
ATC
salmeterol; inhalant
2.7
6.0
39
148
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.8
6.0
36
132
UDC00
NOMESCO Finland
Ear microscopy
2.0
6.0
71
364
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.0
181
1237
3AC01
NOMESCO Finland
NA
5.6
6.0
16
29
C82.1
ICD-10 Finland
Follicular lymphoma grade II
5.6
6.0
16
29

Mortality – FinRegistry

Association

Association between endpoint J10_PNEUMONONBACT and mortality.

Females

Parameter HR [95% CI] p-value
J10_PNEUMONONBACT 3.241 [2.53, 4.15] < 0.001
Birth year 0.999 [0.99, 1.01] 0.776

During the follow-up period (1.1.1998 — 31.12.2019), 589 out of 1540 females with J10_PNEUMONONBACT died.

Males

Parameter HR [95% CI] p-value
J10_PNEUMONONBACT 3.747 [2.93, 4.8] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 889 out of 1940 males with J10_PNEUMONONBACT died.

Mortality risk

Mortality risk for people of age

years, who have J10_PNEUMONONBACT.

N-year risk Females Males
1 0.373% 0.717%
5 2.086% 3.691%
10 5.952% 9.123%
15 10.65% 17.786%
20 18.24% 28.582%

Relationships between endpoints

Index endpoint: J10_PNEUMONONBACT – Pneumonia due to other infectious organisms, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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