info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Posteruptive colour changes of dental hard tissues

K11_COLOR_ERUPTIVE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K03.7
  • Hospital discharge: ICD-9 5217
  • Hospital discharge: ICD-8 5217
  • Cause of death: ICD-10 K03.7
  • Cause of death: ICD-9 5217
  • Cause of death: ICD-8 5217

2 out of 7 registries used, show all original rules.

17

4. Check minimum number of events

None

17

5. Include endpoints

None

17

6. Filter based on genotype QC (FinnGen only)

17

Control definitions (FinnGen only)

Control exclude
K11_ORAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 78 38 38
Only index persons 57 33 24
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 20.07 21.41 16.62
Only index persons 26.31 23.43 30.27

-FinnGen-

Key figures

All Female Male
Number of individuals 17 12 5
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 21.82 26.39 10.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection
6
0
+∞
6.65
5.0
0.0
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
8
13
10.48
4.07
4.0
1.8
e9/l
61.3
82.5
—
8
7
(3007853) Bacteria identified in Skin by Aerobe culture
8
15
8.99
3.73
4.0
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
9
21
7.84
3.66
4.2
2.9
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
7
11
9.88
3.60
37.4
9.6
mg/l
1.2
1.1
—
7
11
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
7
14
7.65
3.11
3.4
1.5
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
10
8.54
2.98
21.8
2.1
mmol/l
24.6
23.2
—
6
10
(3018677) aPTT in Platelet poor plasma by Coagulation assay
8
22
5.89
2.81
16.4
2.2
s
29.0
29.7
—
8
22
(3005719) IgG [Mass/volume] in Serum or Plasma
5
7
9.47
2.74
2.0
3.3
g/l
6.1
9.2
—
5
7
(3000494) Fungus identified in Specimen by Culture
5
7
9.47
2.74
2.4
1.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
11
45
5.04
2.69
16.4
3.7
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
8
24
5.34
2.60
9.3
3.4
%
1.3
1.5
—
8
24
(3036489) Thrombin time
5
8
8.25
2.55
16.6
2.4
s
21.6
23.8
—
5
8
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
5
8
8.25
2.55
16.4
2.4
%
174.4
190.5
—
5
8
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
5
8
8.25
2.55
17.8
2.3
g/l
2.7
2.4
—
5
8
(3000991) Gas panel - Venous blood
8
25
5.09
2.50
34.6
7.6
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
8
26
4.86
2.41
25.0
3.3
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
14
5.98
2.39
15.8
2.1
%
95.5
83.1
—
6
14
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
9
7.31
2.39
1.8
1.2
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
5
9
7.31
2.39
23.6
2.3
g/l
106.8
137.3
—
5
9
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
9
7.31
2.39
5.6
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
28
4.46
2.23
12.6
2.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
10
43
4.18
2.08
12.1
2.7
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
7
23
4.42
2.08
8.4
2.7
umol/l
254.9
302.1
—
7
23
(3015736) pH of Urine
10
45
3.93
2.01
11.3
2.6
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
8
31
3.95
1.99
10.4
2.2
e6/l
4.5
5.7
—
8
31
(3041096) Erythrocytes [Presence] in Urine by Automated
8
31
3.95
1.99
5.6
3.1
—
—
—
0
0
(3012544) pH of Venous blood
8
31
3.95
1.99
36.3
3.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
8
31
3.95
1.99
35.9
3.2
mmol/l
1.1
0.8
—
8
19
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
19
4.28
1.85
1.8
1.7
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
8
33
3.66
1.84
5.0
2.1
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
9
38
3.87
1.83
12.7
3.9
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
11
56
3.70
1.82
31.6
3.2
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
28
3.52
1.68
35.3
12.1
mmol/l
24.3
25.0
—
7
28
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
7
29
3.37
1.61
48.7
7.9
mmol/l
1.7
1.5
—
7
20
(3042936) Bacteria identified in Isolate by Culture
5
16
3.97
1.56
4.4
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
6
23
3.45
1.53
1.8
2.0
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
8
39
2.96
1.40
25.4
4.9
%
96.3
86.7
—
8
39
(3020564) Creatinine [Moles/volume] in Serum or Plasma
17
135
+∞
1.34
46.8
9.9
umol/l
74.3
62.5
0.58
17
135
(3044640) Blood type and Crossmatch panel - Blood
9
47
2.92
1.32
5.3
2.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
10
60
2.60
1.17
7.1
3.2
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
6
27
2.87
1.06
37.3
8.1
mmol/l
24.2
24.6
—
6
27
(3022313) Gas panel - Capillary blood
6
27
2.87
1.06
45.0
8.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
6
28
2.75
1.04
14.3
1.7
mg/l
2.3
1.2
—
6
20
(40761511) CBC panel - Blood by Automated count
17
144
+∞
0.87
43.1
7.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
43
2.06
0.79
2.3
1.8
—
—
—
0
0
(40758558) Short blood count panel - Blood
9
58
2.16
0.74
16.2
5.3
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
6
35
2.09
0.67
4.2
2.1
mg/l
2.6
2.4
—
6
30
(3026008) Bacteria identified in Urine by Culture
7
46
1.88
0.59
7.4
1.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
11
83
1.92
0.51
23.4
4.0
e9/l
0.0
0.0
0.00
11
61
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
0
16
0.00
0.43
0.0
1.4
—
1.1
—
0
5
(3010813) Leukocytes [#/volume] in Blood
17
154
+∞
0.43
68.1
14.8
e9/l
7.2
7.3
0.05
17
149
(3000963) Hemoglobin [Mass/volume] in Blood
17
154
+∞
0.43
68.1
15.2
g/l
124.6
132.4
1.49
17
154
(3026361) Erythrocytes [#/volume] in Blood
17
153
+∞
0.43
68.2
14.9
e12/l
4.2
4.5
1.97
17
148
(3024731) MCV [Entitic volume]
17
153
+∞
0.43
67.8
14.8
fl
90.5
88.2
0.67
17
153
(3035941) MCH [Entitic mass]
17
153
+∞
0.43
67.8
14.8
pg
30.4
29.6
0.67
17
153
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
0
18
0.00
0.42
0.0
1.2
—
51.6
—
0
9
(3003694) ABO and Rh group [Type] in Blood
6
47
1.42
0.24
1.8
1.7
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
5
42
1.27
0.11
2.0
1.8
—
—
—
0
0
(3044889) 12 lead EKG panel
8
72
1.21
0.10
4.6
2.6
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
1.4
—
106.6
—
0
5
(3004959) Base excess in Arterial cord blood by calculation
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood
0
9
0.00
0.00
0.0
1.0
—
18.7
—
0
9
(3022621) pH of Urine by Test strip
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006598) pH of Arterial cord blood
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
18.9
—
0
5
(3002523) Influenza virus A Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009466) Valproate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.4
—
380.2
—
0
5
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
7.5
—
204.2
—
0
6
(3028300) Cannabinoids [Presence] in Urine
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3000492) Spirometry study
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(4010399)
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_COLOR_ERUPTIVE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_COLOR_ERUPTIVE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_COLOR_ERUPTIVE – Posteruptive colour changes of dental hard tissues

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data