No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
213 |
4. Check minimum number of eventsNone |
213 |
5. Include endpointsNone |
213 |
6. Filter based on genotype QC (FinnGen only) |
213 |
Control definitions (FinnGen only)
- Control exclude
- L12_PAPULOSQUAMOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Other and unspecified papulosquamous disorders based on the number of shared cases.
Similar with more cases:
- Other papulosquamous disorders
- Papulosquamous disorders
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2302 | 1336 | 944 |
Only index persons | 1746 | 1046 | 700 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.04 | 0.03 |
Only index persons | 0.03 | 0.04 | 0.03 |
Median age at first event (years) | |||
Whole population | 44.89 | 48.49 | 39.61 |
Only index persons | 39.20 | 43.78 | 32.35 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 213 | 123 | 90 |
Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
Median age at first event (years) | 46.66 | 44.65 | 49.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 196
- Matched controls
- 1959
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint L12_PAPULOSQUONAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
L12_PAPULOSQUONAS | 1.667 [1.17, 2.38] | 0.005 |
Birth year | 0.992 [0.98, 1.0] | 0.063 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 566 females with L12_PAPULOSQUONAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
L12_PAPULOSQUONAS | 1.932 [1.32, 2.84] | < 0.001 |
Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 428 males with L12_PAPULOSQUONAS died.
Mortality risk
Mortality risk for people of age
years, who have L12_PAPULOSQUONAS.N-year risk | Females | Males |
---|---|---|
1 | 0.115% | 0.391% |
5 | 0.836% | 2.163% |
10 | 2.197% | 5.375% |
15 | 4.318% | 10.143% |
20 | 7.431% | 16.83% |
Relationships between endpoints
↥Index endpoint: L12_PAPULOSQUONAS – Other and unspecified papulosquamous disorders
GWS hits: 1