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Other and unspecified papulosquamous disorders

MESH Endpoint Browser PheWeb

L12_PAPULOSQUONAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L44.8, L44.9
  • Hospital discharge: ICD-9 — 697[8-9]|6970
  • Hospital discharge: ICD-8 — 69799|696[5-9]
  • Cause of death: ICD-10 — L44.8, L44.9
  • Cause of death: ICD-9 — 697[8-9]|6970
  • Cause of death: ICD-8 — 69799|696[5-9]

2 out of 7 registries used, show all original rules.

220

4. Check minimum number of events

None

220

5. Include endpoints

None

220

6. Filter based on genotype QC (FinnGen only)

205

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2302 1336 944
Only index persons 1746 1046 700
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 44.89 48.49 39.61
Only index persons 39.20 43.78 32.35

-FinnGen-

Key figures

All Female Male
Number of individuals 205 116 89
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 47.12 45.45 49.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
220
Matched controls
2200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L44.8
ICD-10 Finland
Other specified papulosquamous disorders
+∞
83.8
75
*
L44.9
ICD-10 Finland
Papulosquamous disorder, unspecified
833.0
65.4
61
*
6970A
ICD-9 Finland
Lichen planus[LICHEN RUBER PLANUS]
+∞
57.9
53
*
D07AC01
ATC
betamethasone; topical
5.5
35.1
132
473
D07XC01
ATC
betamethasone; topical
7.1
32.9
59
108
L40.0
ICD-10 Finland
Psoriasis vulgaris
46.8
20.9
25
6
D07AB02
ATC
hydrocortisone butyrate; topical
3.7
19.8
101
413
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.0
17.9
66
215
E0000UV, ,
ATC
3.4
17.7
123
601
D05AX02
ATC
calcipotriol; topical
46.2
17.6
21
5
E000001, ,
ATC
3.6
16.1
68
242
D07AD01
ATC
clobetasol; topical
4.0
16.1
54
164
D05BB02
ATC
acitretin; oral
41.3
15.7
19
5
D07AC13
ATC
mometasone; topical
3.1
14.0
84
366
D05AX52
ATC
calcipotriol, combinations; topical
11.6
13.6
25
24
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.1
12.2
37
103
R06AE07
ATC
cetirizine; oral
2.6
10.7
110
616
L40.5
ICD-10 Finland
Arthropathic psoriasis
+∞
10.5
10
*
E000002, ,
ATC
3.4
9.9
39
130
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
9.4
9
*
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
9.4
9
*
E000003, ,
ATC
5.0
9.0
20
43
D07AA02
ATC
hydrocortisone; topical
2.9
8.8
49
200
L43.8
ICD-10 Finland
Other lichen planus
52.1
8.7
10
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.5
8.3
64
307
D07BC01
ATC
betamethasone and antiseptics; topical
3.2
7.8
33
114
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.3
7.7
31
104
D07AB08
ATC
desonide; topical
3.0
7.6
37
139
N05BB01
ATC
hydroxyzine; systemic
3.9
7.5
23
64
69698
ICD-8 Finland
Psoriasis and similar disorders, Other disorders
+∞
7.3
7
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.3
7.2
19
47
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
6.7
75
419
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
6.5
72
399
69699, ,
ICD-8 Finland
+∞
6.3
6
*
L04AX01
ATC
azathioprine; systemic
5.9
6.1
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
45
207
2.48
6.24
1.5
1.4
213.33
493.33
titre
1.47
12
42
17
45
4.01
5.93
1.5
1.4
282.11
284.18
ug/g
—
9
28
41
191
2.41
5.50
1.5
1.4
—
—
—
0
0
34
146
2.57
5.41
7.4
6.9
—
—
—
0
0
40
186
2.41
5.39
5.7
2.8
1.81
1.74
%
0.18
35
167
37
170
2.41
5.11
2.3
1.7
—
—
—
0
0
36
168
2.37
4.80
3.4
3.8
2.07
2.28
mmol/l
0.10
29
125
107
747
1.84
4.71
6.8
4.4
35.41
35.86
g/l
0.38
100
704
101
695
1.84
4.64
3.7
3.7
5.71
5.77
ph
—
7
51
73
462
1.87
4.32
4.9
4.3
—
—
—
0
0
119
877
1.78
4.23
9.9
5.6
2.14
2.08
e9/l
0.09
106
784
110
794
1.77
4.19
9.9
6.5
—
—
—
0
0
133
1015
1.78
4.17
14.7
9.1
4.59
4.08
e9/l
1.04
115
878
50
283
1.99
4.10
2.8
2.1
11.44
13.07
umol/l
0.86
50
259
119
883
1.76
4.08
10.5
5.7
0.21
0.18
e9/l
0.79
106
776
68
430
1.84
3.99
3.4
1.9
3.11
3.09
mg/l
0.02
61
371
116
858
1.74
3.99
9.9
5.6
0.58
0.56
e9/l
0.59
101
743
116
858
1.74
3.99
9.9
5.6
0.04
0.04
e9/l
0.50
101
742
8
11
7.50
3.89
1.6
1.2
—
—
—
0
0
9
15
6.20
3.85
1.2
1.1
—
—
—
0
0
63
396
1.83
3.75
4.0
4.0
—
—
—
0
0
94
673
1.69
3.52
2.5
1.9
104.92
95.46
pmol/l
0.76
55
338
28
135
2.23
3.46
3.3
2.6
71.88
67.82
e9/l
0.30
21
105
101
744
1.66
3.35
3.4
2.6
100.09
105.62
ug/l
0.19
96
687
68
452
1.73
3.30
10.4
6.9
—
—
—
0
0
17
66
2.71
3.30
1.5
1.2
—
—
—
0
0
13
39
3.48
3.28
3.1
3.3
—
—
—
0
0
114
871
1.64
3.25
7.2
6.0
1.21
1.22
mmol/l
0.29
103
741
56
359
1.75
3.07
2.7
1.4
2.60
2.27
g/l
0.40
32
201
107
816
1.61
3.00
9.9
5.6
54.14
56.46
%
1.08
102
771
73
508
1.65
2.95
4.3
3.7
7.73
8.85
mg/mmol
0.12
54
312
74
517
1.65
2.94
3.9
3.2
6.71
7.46
mmol/l
1.02
65
441
47
293
1.77
2.82
1.3
1.3
28.87
44.81
iu/ml
0.43
14
90
104
797
1.58
2.80
7.2
5.4
1.21
1.22
mmol/l
0.28
97
730
26
133
2.08
2.79
2.3
3.4
112.67
70.28
ng/l
1.27
21
123
112
877
1.56
2.72
4.0
4.0
0.00
0.00
estimate
—
10
164
87
643
1.58
2.72
4.7
3.8
21.86
65.76
e6/l
2.53
65
459
36
209
1.86
2.71
6.5
6.5
104.69
103.80
mmol/l
0.46
36
209
11
35
3.25
2.68
1.5
1.3
—
—
—
0
0
142
1183
1.57
2.55
5.2
4.3
—
—
—
0
0
110
868
1.53
2.52
4.1
3.9
0.00
0.00
estimate
-0.00
12
177
47
303
1.70
2.50
1.7
1.9
—
—
—
0
0
76
554
1.57
2.48
3.8
3.3
13.84
158.22
e6/l
0.68
61
430
44
280
1.71
2.45
3.7
3.0
3.26
2.97
e6/l
0.06
23
150
11
38
2.99
2.45
1.1
1.1
—
—
—
0
0
60
418
1.60
2.36
3.7
2.7
378.16
4227.87
umol/l
1.31
55
353
24
128
1.98
2.32
1.7
1.4
—
—
—
0
0
47
310
1.66
2.29
1.8
1.7
1145.58
1213.19
nmol/l
0.22
38
230
37
229
1.74
2.27
4.3
2.0
136.16
127.16
ug/g
0.08
32
180
68
492
1.55
2.27
3.6
3.1
—
—
—
0
0
17
80
2.22
2.25
4.9
3.4
—
—
—
0
0
5
9
5.65
2.22
1.0
1.6
16.02
13.90
umol/l
—
5
9
56
389
1.59
2.22
4.7
4.2
1.02
1.02
kg/l
—
9
55
36
223
1.73
2.20
1.4
1.2
—
—
—
0
0
14
61
2.38
2.19
2.6
3.6
20.86
22.20
s
0.30
14
55
21
109
2.02
2.19
4.7
2.2
—
—
—
0
0
19
95
2.09
2.18
1.5
1.2
427.29
148.04
u/ml
0.45
19
83
26
146
1.89
2.18
7.9
5.7
1.21
1.31
mmol/l
0.32
26
139
11
42
2.70
2.17
1.3
1.3
—
—
—
0
0
108
871
1.47
2.11
5.6
5.2
0.00
0.00
estimate
-0.00
11
166
7
20
3.58
2.07
1.0
1.0
—
—
—
0
0
69
510
1.51
2.07
3.8
3.2
0.19
0.33
e6/l
0.75
54
385
25
143
1.84
1.99
6.0
4.0
2.83
0.87
%
0.78
12
58
149
1290
1.48
1.96
6.0
3.9
12.93
11.89
mm/h
0.43
140
1181
53
374
1.55
1.95
2.2
1.9
1.54
1.24
mg/l
0.33
37
291
5
11
4.62
1.95
2.2
1.5
—
—
—
0
0
5
11
4.62
1.95
1.0
1.1
—
—
—
0
0
5
11
4.62
1.95
3.2
2.3
—
—
—
0
0
55
393
1.53
1.92
1.7
1.4
0.73
1.85
u/ml
1.04
14
95
65
482
1.49
1.90
3.8
3.2
51.94
324.39
mg/l
0.82
47
305
7
22
3.25
1.89
2.0
3.7
—
—
—
0
0
191
1751
1.69
1.88
22.5
13.9
22.98
23.50
mg/l
0.07
155
1365
0
54
0.00
1.88
0.0
1.5
—
258.72
—
0
26
29
177
1.74
1.88
1.2
1.5
—
—
—
0
0
153
1338
1.47
1.86
10.9
7.1
83.03
80.03
u/l
0.37
147
1255
173
1554
1.53
1.81
8.1
5.7
42.23
39.72
mmol/mol
1.89
166
1450
7
23
3.11
1.81
1.0
1.0
—
—
—
0
0
112
930
1.42
1.78
7.7
6.0
11.17
11.85
umol/l
0.37
104
878
19
103
1.92
1.78
1.2
1.1
99.24
131.41
iu/ml
—
7
39
6
18
3.40
1.76
1.8
1.2
—
—
—
0
0
23
134
1.80
1.74
6.4
4.1
0.65
0.19
%
—
10
48
57
419
1.49
1.73
5.2
3.8
92.93
91.20
%
0.20
57
412
151
1326
1.44
1.73
4.6
3.9
14.85
14.81
pmol/l
0.06
140
1196
12
55
2.25
1.70
10.2
13.5
—
—
—
0
0
180
1640
1.54
1.67
5.3
4.5
6.37
5.91
mmol/l
2.13
168
1503
7
25
2.86
1.66
1.7
1.8
—
—
—
0
0
26
160
1.71
1.65
1.7
1.5
—
—
—
0
0
49
353
1.50
1.64
3.1
3.2
512.67
543.68
mosm/kgh2o
0.46
43
312
8
32
2.56
1.61
1.3
1.5
—
—
—
0
0
10
44
2.33
1.58
2.1
1.3
—
—
—
0
0
35
237
1.57
1.54
2.6
1.9
—
—
—
0
0
36
246
1.55
1.53
1.3
1.5
—
—
—
0
0
96
792
1.38
1.52
15.1
13.8
1.18
1.23
inr
0.19
19
231
24
149
1.69
1.48
1.3
1.2
—
—
—
0
0
38
265
1.52
1.48
2.3
2.3
30.76
29.58
s
0.38
38
257
58
441
1.43
1.47
1.8
1.5
19.93
21.20
nmol/l
0.26
53
375
5
16
3.17
1.44
1.2
1.9
—
—
—
0
0
21
127
1.72
1.42
5.6
3.8
0.63
0.44
%
—
8
45
10
46
2.23
1.42
1.0
1.8
204.80
298.66
mu/l
—
10
41
38
268
1.51
1.40
1.3
1.3
1.11
12.60
u/ml
2.54
12
107
19
112
1.76
1.40
4.9
7.1
24.14
25.07
mmol/l
0.56
19
112
68
536
1.39
1.40
4.8
3.7
7.39
7.40
ph
—
8
102
6
23
2.65
1.37
1.0
1.2
—
—
—
0
0
5
17
2.98
1.36
1.0
1.2
—
—
—
0
0
74
600
1.35
1.27
4.4
3.1
2.35
2.36
mmol/l
0.25
68
532
12
63
1.96
1.25
1.0
1.1
—
—
—
0
0
44
574
0.71
1.24
3.5
2.9
—
—
—
0
0
69
556
1.35
1.23
4.0
2.9
—
—
—
0
0
13
71
1.88
1.22
2.0
4.4
—
—
—
0
0
5
19
2.67
1.22
1.2
2.2
15.28
17.55
ug/l
—
5
19
8
151
0.51
1.19
3.9
3.9
—
—
—
0
0
18
112
1.66
1.13
5.5
3.3
—
7.43
—
0
14
173
1603
1.37
1.11
5.7
4.7
1.94
1.91
mu/l
0.13
162
1471
10
52
1.97
1.08
1.7
1.7
—
—
—
0
0
10
52
1.97
1.08
1.5
1.3
—
—
—
0
0
80
671
1.30
1.06
2.3
2.1
—
—
—
0
0
18
114
1.63
1.06
5.5
3.2
5.33
5.10
kpa
0.69
18
109
92
787
1.29
1.05
10.4
10.1
0.01
0.00
e9/l
0.28
75
644
65
531
1.32
1.04
3.4
2.3
—
—
—
0
0
27
190
1.48
1.03
7.5
6.2
0.15
1.26
mmol/l
0.68
20
150
42
324
1.37
0.98
5.0
3.6
482.45
181.66
ng/l
0.46
33
253
7
36
1.97
0.98
1.6
1.5
60.29
104.13
e6/l
—
7
30
7
36
1.97
0.98
1.4
1.3
1.00
3.68
e6/l
—
7
28
66
547
1.30
0.95
3.8
2.5
56.33
66.11
u/l
0.54
58
513
24
168
1.48
0.94
1.6
1.5
—
—
—
0
0
12
70
1.76
0.94
1.1
1.1
—
—
—
0
0
193
1834
1.43
0.94
15.1
10.0
27.20
24.50
u/l
1.51
188
1775
17
110
1.59
0.93
1.1
1.5
—
—
—
0
0
6
28
2.17
0.92
2.0
1.3
—
—
—
0
0
6
30
2.03
0.87
1.3
1.3
—
—
—
0
0
26
189
1.43
0.86
1.7
1.3
—
—
—
0
0
8
45
1.81
0.85
9.2
3.6
26.63
25.78
mg/l
—
8
35
6
31
1.96
0.85
8.8
4.4
—
—
—
0
0
187
1777
1.35
0.82
23.1
15.9
139.52
139.77
mmol/l
0.68
182
1732
187
1782
1.33
0.76
23.3
16.0
3.97
3.97
mmol/l
0.09
182
1738
5
24
2.11
0.75
1.6
1.5
—
—
—
0
0
129
1181
1.22
0.74
3.8
3.9
—
—
—
0
0
5
26
1.94
0.71
4.8
10.8
4.76
6.62
mmol/l
—
5
21
175
1661
1.26
0.68
5.1
4.4
4.51
4.64
mmol/l
0.85
166
1534
20
148
1.39
0.62
4.0
3.4
—
—
—
0
0
5
30
1.68
0.62
1.6
1.4
—
—
—
0
0
5
30
1.68
0.62
1.8
1.5
—
—
—
0
0
5
30
1.68
0.62
1.8
1.5
—
—
—
0
0
10
149
0.66
0.59
1.2
1.2
—
—
—
0
0
6
35
1.73
0.58
3.2
2.3
—
—
—
0
0
15
205
0.71
0.57
1.7
1.3
—
—
—
0
0
6
36
1.68
0.57
2.5
2.8
4.80
4.57
e9/l
—
6
36
6
36
1.68
0.57
2.7
2.9
63.00
59.42
%
—
6
36
6
37
1.64
0.56
1.0
1.2
—
—
—
0
0
12
82
1.49
0.55
2.8
3.1
0.52
0.73
%
1.73
12
82
200
1941
1.33
0.55
31.7
20.2
250.57
250.26
e9/l
0.02
191
1898
200
1941
1.33
0.55
31.5
20.1
30.18
30.23
pg
0.15
193
1918
200
1941
1.33
0.55
31.6
20.2
90.93
90.84
fl
0.10
193
1918
200
1942
1.33
0.54
31.7
20.3
7.22
6.74
e9/l
1.45
191
1888
200
1942
1.33
0.54
31.8
20.2
4.52
4.48
e12/l
0.66
191
1893
14
100
1.43
0.53
1.6
1.2
—
—
—
0
0
12
83
1.47
0.53
14.2
6.4
—
—
—
0
0
200
1945
1.31
0.50
31.8
20.3
135.39
134.86
g/l
0.19
194
1918
7
45
1.57
0.49
10.4
3.6
149.93
186.55
mg/l
—
7
35
12
85
1.44
0.48
2.7
3.1
1.09
1.27
%
0.25
12
85
5
32
1.58
0.42
1.8
1.5
—
—
—
0
0
8
59
1.37
0.41
1.3
1.2
—
—
—
0
0
199
1942
1.26
0.41
32.1
20.2
40.02
40.16
%
0.11
184
1823
72
654
1.15
0.40
4.1
3.9
22.07
36.13
ng/l
1.40
48
452
55
491
1.16
0.39
4.9
4.2
0.00
0.00
estimate
—
10
161
14
107
1.33
0.38
1.2
1.3
—
31.86
—
0
10
171
1651
1.16
0.37
4.8
4.3
1.37
1.49
mmol/l
3.00
162
1516
5
37
1.36
0.37
3.6
4.4
4.82
4.95
kpa
—
5
37
5
37
1.36
0.37
3.6
4.4
6.82
8.51
kpa
—
5
37
5
37
1.36
0.37
3.6
4.4
0.68
2.37
mmol/l
—
5
24
9
122
0.73
0.36
2.9
2.6
—
—
—
0
0
14
108
1.32
0.36
2.3
3.7
—
—
—
0
0
45
506
0.86
0.36
4.5
3.9
—
—
—
0
0
6
42
1.44
0.36
1.7
1.6
58.83
320.06
pmol/l
—
6
42
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
187
1824
1.17
0.31
17.2
13.1
—
—
—
0
0
7
53
1.33
0.31
3.1
4.8
—
—
—
0
0
15
122
1.25
0.27
2.1
2.4
—
22.46
—
0
5
174
1695
1.13
0.26
5.9
4.9
2.62
2.73
mmol/l
0.85
163
1556
6
82
0.72
0.24
3.0
3.0
48.67
494.30
u/ml
—
6
73
11
88
1.26
0.23
2.0
1.2
—
—
—
0
0
5
39
1.29
0.23
1.2
1.1
—
—
—
0
0
188
1844
1.13
0.23
24.9
16.1
75.35
75.94
umol/l
0.08
188
1844
5
40
1.26
0.22
5.4
4.8
12.62
31.74
mg/l
—
5
25
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
8.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
7.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
209.60
—
0
13
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
118
1138
1.08
0.19
4.4
2.9
53.50
42.56
u/l
0.74
111
1064
7
61
1.15
0.17
2.0
2.7
—
—
—
0
0
6
76
0.78
0.16
1.0
1.7
—
—
—
0
0
43
460
0.92
0.16
1.3
1.4
—
—
—
0
0
9
81
1.12
0.15
1.8
1.8
—
—
—
0
0
31
285
1.10
0.15
2.5
3.0
0.77
0.76
ug/l
0.02
22
185
162
1590
1.07
0.14
4.5
3.9
1.42
1.25
mmol/l
2.26
151
1453
8
97
0.82
0.14
4.3
3.8
—
—
—
0
0
16
146
1.10
0.08
1.3
1.4
—
—
—
0
0
50
486
1.04
0.05
3.5
3.5
—
—
—
0
0
16
151
1.06
0.03
2.9
2.3
8.69
5.20
ug/l
0.28
16
133
16
152
1.06
0.02
1.8
1.8
—
—
—
0
0
16
167
0.95
0.01
1.8
1.7
—
—
—
0
0
16
158
1.01
0.00
3.8
3.8
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
93
0.97
-0.00
2.3
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
32.25
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
35613.13
—
0
8
6
62
0.97
-0.00
1.2
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
2050.00
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
17.10
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
1.61
—
0
6
0
5
0.00
-0.00
0.0
4.2
—
3.58
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint L12_PAPULOSQUONAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_PAPULOSQUONAS 1.667 [1.17, 2.38] 0.005
Birth year 0.992 [0.98, 1.0] 0.063

During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 566 females with L12_PAPULOSQUONAS died.

Males

Parameter HR [95% CI] p-value
L12_PAPULOSQUONAS 1.932 [1.32, 2.84] < 0.001
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 428 males with L12_PAPULOSQUONAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_PAPULOSQUONAS.

N-year risk Females Males
1 0.115% 0.391%
5 0.836% 2.163%
10 2.197% 5.375%
15 4.318% 10.143%
20 7.431% 16.83%

Relationships between endpoints

↥

Index endpoint: L12_PAPULOSQUONAS – Other and unspecified papulosquamous disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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