Other and unspecified papulosquamous disorders

L12_PAPULOSQUONAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L44.8, L44.9
  • Hospital discharge: ICD-9 697[8-9]|6970
  • Hospital discharge: ICD-8 69799|696[5-9]
  • Cause of death: ICD-10 L44.8, L44.9
  • Cause of death: ICD-9 697[8-9]|6970
  • Cause of death: ICD-8 69799|696[5-9]

2 out of 7 registries used, show all original rules.

213

4. Check minimum number of events

None

213

5. Include endpoints

None

213

6. Filter based on genotype QC (FinnGen only)

213

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2302 1336 944
Only index persons 1746 1046 700
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 44.89 48.49 39.61
Only index persons 39.20 43.78 32.35

-FinnGen-

Key figures

All Female Male
Number of individuals 213 123 90
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 46.66 44.65 49.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
196
Matched controls
1959
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L44.8
ICD-10 Finland
Other specified papulosquamous disorders
+∞
76.1
68
*
6970A
ICD-9 Finland
Lichen planus[LICHEN RUBER PLANUS]
+∞
53.6
49
*
L44.9
ICD-10 Finland
Papulosquamous disorder, unspecified
643.0
52.0
49
*
D07AC01
ATC
betamethasone; topical
5.3
26.0
111
387
L40.0
ICD-10 Finland
Psoriasis vulgaris
246.4
22.1
22
*
D07XC01
ATC
betamethasone, combinations; topical
7.8
21.8
54
91
D05AX52
ATC
calcipotriol, combinations; topical
18.9
16.6
25
15
E0000UV
ATC
NA
3.5
15.6
106
491
D05BB02
ATC
acitretin; oral
24.6
13.2
18
8
D07AB02
ATC
hydrocortisone butyrate; topical
3.4
13.0
81
339
D05AX02
ATC
calcipotriol; topical
13.7
12.5
21
17
E000001
ATC
NA
3.8
12.4
60
205
D07AA02
ATC
hydrocortisone; topical
4.5
12.0
46
126
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.8
11.9
56
186
D07AC13
ATC
mometasone; topical
3.1
10.7
73
318
E000002
ATC
NA
4.7
10.5
37
93
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
9.4
9
*
D07AB08
ATC
desonide; topical
4.1
8.8
35
99
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
8.4
8
*
L40.5
ICD-10 Finland
Arthropathic psoriasis
+∞
8.4
8
*
L43.8
ICD-10 Finland
Other lichen planus
34.9
8.2
10
*
D07AD01
ATC
clobetasol; topical
3.4
8.2
41
141
R06AE07
ATC
cetirizine; oral
2.4
7.8
94
547
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.0
7.5
30
85
69698
ICD-8 Finland
Psoriasis and similar disorders, Other disorders
+∞
7.3
7
*
TQW80
NOMESCO Finland
Local dermatologic skincare
10.6
7.1
13
13
E000003
ATC
NA
6.9
6.8
16
25
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.6
6.7
54
249
D07AB01
ATC
clobetasone; topical
7.3
6.7
15
22
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
6.5
29
91
103
Kela drug reimbursment
Diabetes, insulin-treated
2.4
6.3
61
310
69699
ICD-8 Finland
NA
+∞
6.3
6
*
L40.8
ICD-10 Finland
Other psoriasis
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
45
4.02
5.94
1.5
1.4
282.1
284.2
ug/g
—
9
28
39
181
2.41
5.29
5.8
2.9
1.8
1.7
%
0.21
34
162
40
188
2.39
5.27
1.5
1.4
—
—
—
0
0
37
172
2.39
4.99
3.4
3.8
—
—
—
0
0
36
167
2.39
4.87
3.4
3.8
2.1
2.3
mmol/l
0.07
28
121
36
169
2.36
4.75
2.3
1.7
—
—
—
0
0
32
143
2.46
4.69
7.7
7.0
—
—
—
0
0
40
199
2.24
4.61
1.5
1.4
213.3
503.4
titre
1.51
12
41
102
725
1.78
4.12
7.0
4.5
35.4
35.8
g/l
0.39
95
683
13
38
3.58
3.97
3.4
3.3
—
—
—
0
0
49
280
1.97
3.92
2.8
2.1
11.6
13.0
umol/l
0.69
49
254
66
418
1.84
3.87
3.5
1.9
3.1
3.1
mg/l
0.03
60
360
22
90
2.61
3.86
3.3
4.0
24.1
24.4
mmol/l
0.13
17
82
9
15
6.21
3.86
1.2
1.1
—
—
—
0
0
70
453
1.81
3.82
5.1
4.4
—
—
—
0
0
28
132
2.29
3.65
3.3
2.7
71.9
67.7
e9/l
0.30
21
103
127
985
1.72
3.59
14.8
9.2
4.6
4.1
e9/l
1.15
111
852
113
855
1.69
3.46
10.1
5.6
2.1
2.1
e9/l
0.07
102
759
92
660
1.69
3.43
2.5
1.9
107.1
95.5
pmol/l
1.01
53
334
113
861
1.67
3.32
10.8
5.7
0.2
0.2
e9/l
0.75
102
757
110
836
1.65
3.24
10.1
5.6
0.6
0.6
e9/l
0.66
97
722
110
837
1.65
3.22
10.3
5.7
0.0
0.0
e9/l
0.40
97
724
7
11
6.54
3.21
1.7
1.2
—
—
—
0
0
72
496
1.68
3.06
4.4
3.9
7.9
9.0
mg/mmol
0.11
53
307
59
387
1.73
2.99
4.2
4.0
—
—
—
0
0
11
35
3.26
2.97
1.5
1.3
—
—
—
0
0
72
503
1.65
2.88
4.0
3.2
6.5
7.5
mmol/l
1.65
63
426
53
346
1.71
2.72
2.8
1.4
2.6
2.3
g/l
0.42
32
190
77
556
1.60
2.67
9.5
5.5
—
—
—
0
0
64
442
1.64
2.65
10.8
7.0
—
—
—
0
0
100
776
1.54
2.50
7.3
5.4
1.2
1.2
mmol/l
0.43
93
710
25
132
2.01
2.48
2.3
3.3
106.6
70.5
ng/l
1.01
20
122
11
40
2.85
2.41
1.3
1.3
—
—
—
0
0
44
283
1.70
2.37
1.3
1.3
30.8
42.0
iu/ml
0.26
13
87
55
376
1.62
2.35
4.7
4.3
1.0
1.0
kg/l
—
8
54
14
59
2.47
2.34
2.6
3.6
20.9
22.3
s
0.32
14
53
10
35
2.95
2.34
1.1
1.1
—
—
—
0
0
34
204
1.79
2.32
6.6
6.6
104.6
103.6
mmol/l
0.49
34
198
101
796
1.51
2.29
10.2
5.7
54.4
56.4
%
0.86
96
749
107
854
1.51
2.29
4.1
4.0
0.0
0.0
estimate
—
10
162
36
221
1.76
2.28
4.4
2.0
140.4
129.5
ug/g
0.10
31
174
17
80
2.22
2.25
4.9
3.4
—
—
—
0
0
5
9
5.66
2.22
1.0
1.6
16.0
13.9
umol/l
—
5
9
53
364
1.61
2.21
2.2
2.0
1.5
1.3
mg/l
0.31
37
284
46
305
1.65
2.21
1.8
1.7
1145.5
1215.3
nmol/l
0.22
37
225
25
140
1.89
2.12
6.0
4.0
3.0
0.9
%
—
10
49
105
845
1.48
2.10
4.1
3.9
0.0
0.0
estimate
—
10
167
136
1153
1.50
2.09
5.3
4.3
—
—
—
0
0
5
10
5.09
2.08
1.6
1.2
—
—
—
0
0
35
219
1.72
2.08
1.4
1.2
—
—
—
0
0
23
126
1.93
2.08
1.7
1.3
—
—
—
0
0
44
293
1.63
2.07
1.7
1.9
—
—
—
0
0
14
64
2.27
1.99
1.6
1.2
—
—
—
0
0
64
470
1.52
1.98
3.9
3.1
53.0
329.6
mg/l
0.81
46
300
5
11
4.63
1.95
1.0
1.1
—
—
—
0
0
5
11
4.63
1.95
3.2
2.4
—
—
—
0
0
20
107
1.96
1.94
4.8
2.2
—
—
—
0
0
0
51
0.00
1.91
0.0
1.5
—
248.7
—
0
24
28
169
1.76
1.89
1.2
1.5
—
—
—
0
0
8
28
2.93
1.88
1.3
1.6
—
—
—
0
0
26
154
1.78
1.86
1.7
1.5
—
—
—
0
0
23
131
1.85
1.86
6.5
4.2
0.7
0.2
%
—
10
43
12
54
2.30
1.77
10.2
13.7
—
—
—
0
0
81
636
1.44
1.77
4.7
3.8
23.0
66.3
e6/l
2.37
61
455
6
18
3.40
1.76
1.8
1.2
—
—
—
0
0
71
546
1.45
1.73
3.8
3.3
14.0
160.0
e6/l
0.68
57
425
56
411
1.49
1.72
3.9
2.7
380.6
4306.2
umol/l
1.31
51
346
103
849
1.41
1.71
5.6
5.3
0.0
0.0
estimate
0.00
11
164
52
377
1.50
1.69
1.7
1.4
0.7
1.7
u/ml
0.88
14
91
35
232
1.61
1.68
2.6
1.9
—
—
—
0
0
6
19
3.22
1.67
1.0
1.0
—
—
—
0
0
38
258
1.58
1.66
2.3
2.3
30.8
29.4
s
0.44
38
250
146
1285
1.43
1.64
4.6
3.9
14.9
14.8
pmol/l
0.15
135
1159
167
1508
1.50
1.63
8.2
5.7
42.4
39.8
mmol/mol
1.96
160
1405
18
99
1.89
1.63
1.2
1.2
99.2
133.9
iu/ml
—
7
38
174
1585
1.53
1.62
5.3
4.5
6.4
5.9
mmol/l
2.25
162
1449
184
1697
1.62
1.62
22.7
14.1
23.0
23.5
mg/l
0.07
149
1325
17
92
1.92
1.61
1.5
1.2
154.0
134.0
u/ml
0.08
17
80
11
50
2.27
1.60
1.6
1.7
—
—
—
0
0
10
44
2.34
1.55
1.0
1.8
204.8
286.1
mu/l
—
10
39
147
1301
1.42
1.55
10.8
7.2
83.2
80.4
u/l
0.31
140
1219
35
237
1.57
1.55
1.3
1.5
—
—
—
0
0
5
15
3.39
1.53
1.2
1.9
—
—
—
0
0
54
403
1.46
1.52
5.3
3.8
92.4
90.9
%
0.16
54
397
142
1252
1.40
1.51
6.2
4.0
13.2
11.9
mm/h
0.54
133
1145
63
486
1.42
1.49
3.6
3.1
—
—
—
0
0
6
22
2.78
1.44
2.2
3.7
—
—
—
0
0
6
22
2.78
1.44
1.0
1.0
—
—
—
0
0
6
22
2.78
1.44
1.0
1.2
—
—
—
0
0
57
434
1.43
1.44
1.8
1.6
20.0
21.2
nmol/l
0.23
52
370
107
907
1.36
1.42
7.6
6.1
11.3
11.9
umol/l
0.29
99
856
80
650
1.37
1.38
7.6
9.1
1.2
1.2
inr
0.05
16
201
5
17
2.99
1.36
1.0
1.2
—
—
—
0
0
64
504
1.39
1.33
3.8
3.2
0.2
0.3
e6/l
0.60
50
382
12
62
1.99
1.30
1.0
1.1
—
—
—
0
0
9
44
2.09
1.28
2.2
1.3
—
—
—
0
0
66
526
1.37
1.27
4.8
3.7
7.4
7.4
ph
—
8
99
13
70
1.91
1.27
2.0
4.4
—
—
—
0
0
46
345
1.43
1.26
3.1
3.0
524.2
551.8
mosm/kgh2o
0.38
40
305
49
372
1.41
1.26
7.2
5.3
—
—
—
0
0
79
651
1.34
1.22
2.3
2.1
—
—
—
0
0
5
19
2.67
1.22
1.4
1.9
—
—
—
0
0
5
19
2.67
1.22
1.4
1.9
—
—
—
0
0
5
19
2.67
1.22
1.4
1.9
—
—
—
0
0
5
19
2.67
1.22
1.2
2.2
15.3
17.6
ug/l
—
5
19
5
19
2.67
1.22
1.4
1.9
—
—
—
0
0
36
261
1.46
1.18
1.3
1.3
1.1
12.8
u/ml
2.54
12
105
18
111
1.68
1.16
4.9
7.1
24.0
25.0
mmol/l
0.64
18
111
43
557
0.71
1.16
3.4
2.9
—
—
—
0
0
66
534
1.34
1.15
3.8
2.5
56.0
57.9
u/l
0.17
57
499
22
144
1.59
1.14
1.3
1.2
—
—
—
0
0
18
112
1.66
1.13
5.5
3.3
—
7.4
—
0
14
64
517
1.34
1.12
3.4
2.3
—
—
—
0
0
66
537
1.33
1.10
4.1
2.9
—
—
—
0
0
8
149
0.52
1.08
3.9
3.9
—
—
—
0
0
18
114
1.63
1.06
5.5
3.2
5.3
5.1
kpa
0.64
18
105
9
46
2.00
1.05
1.4
1.3
—
—
—
0
0
12
68
1.81
1.03
1.1
1.1
—
—
—
0
0
70
581
1.31
1.01
3.9
3.1
2.3
2.4
mmol/l
0.43
64
511
7
35
2.03
1.01
1.6
1.5
60.3
107.7
e6/l
—
7
29
7
35
2.03
1.01
1.4
1.3
1.0
3.7
e6/l
—
7
27
167
1554
1.35
0.99
5.7
4.7
1.9
1.9
mu/l
0.16
156
1422
6
27
2.26
0.94
2.0
1.3
—
—
—
0
0
8
44
1.85
0.87
9.3
3.7
26.6
26.0
mg/l
—
8
34
23
163
1.46
0.86
1.7
1.5
—
—
—
0
0
6
31
1.96
0.85
8.8
4.4
—
—
—
0
0
170
1600
1.31
0.82
5.1
4.4
4.5
4.6
mmol/l
0.70
161
1472
40
316
1.33
0.82
5.3
3.5
513.2
185.4
ng/l
0.47
31
247
16
106
1.55
0.81
1.1
1.5
—
—
—
0
0
25
184
1.41
0.78
7.9
6.2
0.1
1.2
mmol/l
0.59
18
142
156
1457
1.26
0.77
25.2
17.0
14.0
13.6
%
0.95
151
1434
181
1723
1.34
0.76
23.4
16.1
139.5
139.8
mmol/l
0.85
176
1679
186
1778
1.36
0.76
15.2
10.0
27.2
24.5
u/l
1.49
181
1719
5
24
2.11
0.75
1.6
1.5
—
—
—
0
0
20
143
1.44
0.73
4.1
3.4
—
—
—
0
0
25
187
1.38
0.72
1.6
1.3
—
—
—
0
0
5
26
1.94
0.71
4.8
10.8
4.8
6.6
mmol/l
—
5
21
181
1728
1.32
0.70
23.5
16.1
4.0
4.0
mmol/l
0.16
176
1685
5
28
1.80
0.66
1.8
1.4
—
—
—
0
0
5
28
1.80
0.66
1.8
1.4
—
—
—
0
0
5
28
1.80
0.66
1.4
1.3
—
—
—
0
0
7
44
1.61
0.66
10.4
3.7
149.9
191.2
mg/l
—
7
34
5
29
1.74
0.64
1.6
1.5
—
—
—
0
0
5
30
1.68
0.62
1.8
1.5
—
—
—
0
0
14
97
1.47
0.60
1.6
1.2
—
—
—
0
0
6
35
1.73
0.58
3.2
2.3
—
—
—
0
0
6
36
1.69
0.57
1.0
1.2
—
—
—
0
0
6
36
1.69
0.57
2.7
2.9
63.0
59.4
%
—
6
36
6
36
1.69
0.57
2.5
2.8
4.8
4.6
e9/l
—
6
36
72
637
1.20
0.57
4.1
4.0
22.1
36.6
ng/l
1.45
48
444
123
1141
1.18
0.56
3.9
3.9
—
—
—
0
0
55
477
1.21
0.53
4.9
4.2
0.0
0.0
estimate
—
10
159
12
83
1.47
0.53
2.8
3.1
1.1
1.3
%
0.28
12
83
85
769
1.18
0.52
11.0
10.3
0.0
0.0
e9/l
0.29
71
631
15
199
0.74
0.49
1.7
1.2
—
—
—
0
0
166
1591
1.20
0.47
4.8
4.4
1.4
1.5
mmol/l
3.19
157
1455
193
1879
1.29
0.45
32.0
20.5
252.6
250.1
e9/l
0.19
184
1837
193
1879
1.29
0.45
31.8
20.4
30.2
30.2
pg
0.10
186
1856
193
1879
1.29
0.45
31.9
20.4
91.0
90.9
fl
0.14
186
1856
193
1880
1.28
0.44
32.1
20.5
7.3
6.8
e9/l
1.47
184
1826
193
1880
1.28
0.44
32.1
20.5
4.5
4.5
e12/l
0.60
184
1831
11
78
1.43
0.44
15.1
6.4
—
—
—
0
0
10
139
0.71
0.43
1.2
1.2
—
—
—
0
0
8
57
1.42
0.42
1.3
1.1
—
—
—
0
0
14
105
1.36
0.42
2.3
3.7
—
—
—
0
0
193
1883
1.27
0.41
32.1
20.5
135.4
134.8
g/l
0.21
187
1856
5
37
1.36
0.37
3.6
4.4
4.8
5.0
kpa
—
5
37
5
37
1.36
0.37
3.6
4.4
0.7
2.4
mmol/l
—
5
24
5
37
1.36
0.37
3.6
4.4
6.8
8.5
kpa
—
5
37
6
41
1.48
0.36
1.7
1.6
58.8
324.4
pmol/l
—
6
41
6
44
1.37
0.34
1.2
1.3
—
—
—
0
0
44
493
0.86
0.34
4.5
3.9
—
—
—
0
0
13
101
1.31
0.32
1.2
1.3
—
34.4
—
0
9
7
96
0.72
0.31
4.7
3.9
—
—
—
0
0
7
53
1.33
0.31
3.1
4.8
—
—
—
0
0
11
85
1.31
0.28
2.0
1.2
—
—
—
0
0
9
120
0.74
0.28
2.9
2.6
—
—
—
0
0
168
1635
1.13
0.27
5.9
5.0
2.6
2.7
mmol/l
0.67
157
1495
181
1772
1.14
0.25
17.5
13.2
—
—
—
0
0
6
82
0.72
0.24
3.0
3.0
48.7
494.3
u/ml
—
6
73
5
40
1.26
0.22
5.4
4.8
12.6
31.7
mg/l
—
5
25
5
42
1.19
0.21
3.6
4.2
7.4
7.4
ph
—
5
37
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
8.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
7.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
48
1.26
0.20
6.2
2.2
23.8
25.7
mmol/l
—
6
40
157
1532
1.09
0.20
4.6
3.9
1.4
1.2
mmol/l
2.35
146
1397
9
79
1.15
0.15
1.8
1.8
—
—
—
0
0
158
1550
1.07
0.14
24.1
14.2
39.1
39.9
%
0.49
115
1130
181
1788
1.08
0.11
25.1
16.3
75.5
76.0
umol/l
0.08
181
1788
16
144
1.12
0.10
2.9
2.4
8.7
5.3
ug/l
0.27
16
128
6
58
1.04
0.08
1.2
1.3
—
—
—
0
0
6
71
0.84
0.08
1.0
1.8
—
—
—
0
0
43
447
0.95
0.07
1.3
1.5
—
—
—
0
0
15
161
0.93
0.05
1.9
1.8
—
—
—
0
0
16
151
1.06
0.03
3.7
3.8
—
—
—
0
0
29
280
1.04
0.03
2.4
3.0
0.7
0.8
ug/l
0.03
20
182
15
142
1.06
0.02
1.3
1.4
—
—
—
0
0
48
474
1.02
0.00
3.4
3.6
—
—
—
0
0
15
148
1.01
0.00
1.8
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
1.6
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
2050.0
—
0
7
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
3.6
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
0.00
2.2
2.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
9
89
1.01
0.00
2.3
2.2
—
—
—
0
0
6
61
0.98
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
17.1
—
0
5
6
61
0.98
0.00
1.2
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_PAPULOSQUONAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_PAPULOSQUONAS 1.667 [1.17, 2.38] 0.005
Birth year 0.992 [0.98, 1.0] 0.063

During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 566 females with L12_PAPULOSQUONAS died.

Males

Parameter HR [95% CI] p-value
L12_PAPULOSQUONAS 1.932 [1.32, 2.84] < 0.001
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 428 males with L12_PAPULOSQUONAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_PAPULOSQUONAS.

N-year risk Females Males
1 0.115% 0.391%
5 0.836% 2.163%
10 2.197% 5.375%
15 4.318% 10.143%
20 7.431% 16.83%

Relationships between endpoints

Index endpoint: L12_PAPULOSQUONAS – Other and unspecified papulosquamous disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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