colitis: Inflammation of the colon.
Colitis, primary sclerosing, strict definition
DOID EFO Endpoint Browser PheWeb
K11_PSC_COLITIS_STRICT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditions
|
2381 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
389 |
6. Filter based on genotype QC (FinnGen only) |
389 |
Control definitions (FinnGen only)
- Control conditions
- not K11_CHOLANGI
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Colitis, primary sclerosing, strict definition
based on the number of shared cases.
Similar with more cases:
- Colitis, primary sclerosing
- Cholangitis (primary sclerosing, PSC)
- Mucosal proctocolitis
- Ulcerative colitis
- Inflammatory bowel disease
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1356 | 487 | 865 |
| Only index persons | 1293 | 469 | 824 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 36.00 | 36.74 | 35.48 |
| Only index persons | 35.04 | 36.02 | 34.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 389 | 174 | 215 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.09 |
| Median age at first event (years) | 37.81 | 37.94 | 37.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 360
- Matched controls
- 3597
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.5
ICD-10 Finland
Left sided colitis
12302.2
323.0
359
54
K83.0
ICD-10 Finland
Cholangitis
+∞
323.0
358
*
A05AA02
ATC
ursodeoxycholic acid; oral
1052.2
323.0
308
20
A07EC02
ATC
mesalazine; oral, rectal
513.0
323.0
338
104
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
622.5
323.0
340
95
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
1087.5
289.5
246
7
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
152.6
254.5
255
56
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
52.9
205.0
265
180
UJF32
NOMESCO Finland
Coloscopy
40.9
189.4
300
392
UJF30
NOMESCO Finland
Ileoscopy through colon
39.3
171.1
232
158
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
281.4
144.7
139
8
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
188.2
132.9
132
11
L04AX01
ATC
azathioprine; systemic
45.2
132.7
165
66
K51.8
ICD-10 Finland
Other ulcerative colitis
129.2
127.9
132
16
UJK02
NOMESCO Finland
ERCP
98.5
127.3
136
22
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
26.4
119.9
177
127
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
79.5
119.6
132
26
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
79.8
116.9
129
25
WX404
NOMESCO Finland
Intravenous generell anesthesy
13.4
102.5
224
394
A07EA06
ATC
budesonide; oral, local oral
29.9
90.3
124
62
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
103.8
87.1
93
12
WX402
NOMESCO Finland
General anaesthesia
11.2
82.6
187
317
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
82.5
76
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
138.5
82.1
85
8
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
9.4
79.7
215
488
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
96.0
75.9
82
11
ZXE00
NOMESCO Finland
One hour or less
7.7
69.1
258
890
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
48.6
66.4
80
21
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.7
63.6
189
453
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
34.4
63.6
83
31
P01AB01
ATC
metronidazole; oral, rectal
6.8
62.3
246
864
A07EA02
ATC
hydrocortisone; rectal
27.5
57.7
80
37
J01MA12
ATC
levofloxacin; systemic
8.5
57.6
146
267
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
76.0
56.4
63
10
H02AB06
ATC
prednisolone; systemic
6.1
54.8
255
1027
K83.1
ICD-10 Finland
Obstruction of bile duct
114.9
54.7
58
6
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
+∞
54.6
51
*
ZXD10
NOMESCO Finland
Scheduled procedure
6.0
54.5
230
823
Z2221
NOMESCO Finland
Medical doctor
5.9
50.7
189
567
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
68.7
46.8
53
9
WX002
NOMESCO Finland
Sedation and analgesia
6.4
45.8
144
339
J01MA02
ATC
ciprofloxacin; systemic
5.0
43.9
204
747
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
170.8
43.9
45
*
H02AB07
ATC
prednisone; oral
7.4
43.7
117
219
Z94.4
ICD-10 Finland
Liver transplant status
470.3
43.1
42
*
ZX120
NOMESCO Finland
Intravenous
8.8
43.0
100
150
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.0
42.9
121
243
K50.9
ICD-10 Finland
Crohn disease, unspecified
35.8
42.9
55
18
TPH04
NOMESCO Finland
Cathetrisation of vein
6.0
42.6
141
349
K50.8
ICD-10 Finland
Other Crohn disease
25.9
42.2
59
27
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
41.5
39
*
K51
ICD-10 Finland
Ulcerative colitis
39.3
38.3
48
14
K76.9
ICD-10 Finland
Liver disease, unspecified
36.7
37.7
48
15
K50.1
ICD-10 Finland
Crohn disease of large intestine
32.3
36.6
48
17
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
141.1
36.5
38
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
141.1
36.5
38
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
84.4
34.6
38
5
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
102.8
34.4
37
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
11.6
34.4
66
68
K74.3
ICD-10 Finland
Primary biliary cirrhosis
68.4
32.7
37
6
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.8
32.5
80
127
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
96.7
32.4
35
*
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
181.1
32.3
33
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
31.7
30
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
30.7
29
*
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
328.6
30.3
30
*
127
Kela drug reimbursment
Transplant complication
33.4
30.1
39
13
L04AD01
ATC
ciclosporin; systemic
25.5
29.5
41
18
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
30.1
28.6
38
14
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
46.8
28.3
34
8
L01BB02
ATC
mercaptopurine; oral
28.2
28.1
38
15
A07EC01
ATC
sulfasalazine; oral, rectal
6.5
27.8
78
147
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
27.4
26
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
27.4
26
*
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
+∞
26.4
25
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
145.5
26.0
27
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
48.3
26.0
31
7
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.8
25.2
77
161
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
72.7
24.2
27
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
16.8
23.9
38
25
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.6
23.5
49
58
JJ5AT
NOMESCO Finland
NA
+∞
23.2
22
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
15.0
22.9
38
28
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
23.3
22.6
32
15
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.6
22.5
50
66
R50.9
ICD-10 Finland
Fever, unspecified
4.4
22.1
90
255
H02AB04
ATC
methylprednisolone; systemic
4.7
22.1
83
217
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
85.6
21.9
24
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
11.4
21.8
41
40
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
21.6
174
843
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
53.5
21.4
25
5
JN4CD
NOMESCO Finland
Very extensive body CT
10.9
21.2
41
42
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
222.3
20.8
21
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
51.2
20.4
24
5
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
13.2
20.0
35
29
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
19.9
135
572
L04AA06
ATC
mycophenolic acid; systemic
19.1
19.9
30
17
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.3
19.5
79
220
A07EA01
ATC
prednisolone; rectal
36.6
19.1
24
7
WX419
NOMESCO Finland
Other general anesthesy
29.7
19.0
25
9
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
8.7
18.4
40
51
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
17.7
18.2
28
17
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
19.3
18.1
27
15
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
28.4
18.1
24
9
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
9.5
17.9
37
43
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
17.9
17
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.2
17.7
40
54
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
12.9
17.7
31
26
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
188.9
17.7
18
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
17.6
162
823
3AC01
NOMESCO Finland
NA
20.6
17.1
25
13
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
16.1
16.9
27
18
L04AA01
ATC
[U] ciclosporin; systemic
19.1
16.7
25
14
K85.8
ICD-10 Finland
Other acute pancreatitis
42.2
16.5
20
5
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
14.5
16.3
27
20
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.6
16.0
42
71
D94
ICPC
Chronic enteritis/ulcerative colitis
27.7
15.8
21
8
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.5
15.6
81
277
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
33.3
15.0
19
6
1370
FHL
Colonoscopy, whole colon
83.6
14.7
16
*
N02AX02
ATC
tramadol; systemic, rectal
2.5
14.7
166
920
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
9.8
14.5
29
32
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.9
14.4
36
57
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
20.2
14.4
21
11
JN3AD
NOMESCO Finland
Abdominal CT examination
5.1
14.0
45
98
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
13.8
88
347
UJF02
NOMESCO Finland
Peroral enteroscopy
26.9
13.5
18
7
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.9
13.5
38
71
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.6
13.4
48
117
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.4
13.4
50
127
C10AC01
ATC
colestyramine; oral
9.9
13.2
26
28
UJF92
NOMESCO Finland
Capsular endoscopy
9.0
13.0
27
32
Z93.2
ICD-10 Finland
Ileostomy status
72.5
12.7
14
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.4
12.1
26
33
L04AB04
ATC
adalimumab; parenteral
8.4
12.1
26
33
L04AC05
ATC
ustekinumab; parenteral
48.4
12.0
14
*
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
11.5
11
*
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
+∞
11.5
11
*
K83.3
ICD-10 Finland
Fistula of bile duct
+∞
11.5
11
*
A07AA11
ATC
rifaximin; oral
+∞
11.5
11
*
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
123.8
11.5
12
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
8.8
11.5
24
29
Z2446
NOMESCO Finland
Social worker
4.0
11.4
46
126
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
36.3
11.3
14
*
A02BC02
ATC
pantoprazole; systemic
2.2
11.3
224
1553
WVA20
NOMESCO Finland
Medicine administration
9.0
11.2
23
27
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.0
11.0
44
120
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.3
10.9
22
25
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.8
10.8
36
82
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.1
10.6
23
30
A07DA03
ATC
loperamide; oral
7.5
10.5
24
34
JFF10
NOMESCO Finland
Loop enterostomy
33.6
10.4
13
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
33.6
10.4
13
*
Z3226
NOMESCO Finland
Physiotherapist
2.7
10.3
80
350
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
13.7
10.3
17
13
JKA20
NOMESCO Finland
Cholecystectomy
13.7
10.3
17
13
TK800
NOMESCO Finland
Hemodialysis
8.8
10.2
21
25
H02AB09
ATC
hydrocortisone; systemic
8.5
10.0
21
26
JAH00
NOMESCO Finland
Laparotomy
8.2
9.8
21
27
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
56.6
9.7
11
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.2
9.6
36
93
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.8
9.5
31
69
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
9.5
64
255
A07AA09
ATC
vancomycin; oral
18.1
9.5
14
8
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
102.6
9.5
10
*
253
Kela drug reimbursment
NA
+∞
9.4
9
*
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
9.4
9
*
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
+∞
9.4
9
*
3042
Kela drug reimbursment
NA
+∞
9.4
9
*
ZXD05
NOMESCO Finland
Urgent procedure
2.2
9.4
122
688
R4110
NOMESCO Finland
Physiotherapy
2.3
9.2
104
550
A02BC01
ATC
omeprazole; systemic
2.3
9.1
94
475
D64.9
ICD-10 Finland
Anaemia, unspecified
3.8
9.1
38
108
K92.1
ICD-10 Finland
Melaena
5.1
9.1
28
59
JN4BD
NOMESCO Finland
Extensive body CT
3.5
8.9
41
126
K85
ICD-10 Finland
Acute pancreatitis
7.5
8.9
20
28
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
8.7
130
773
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
28.3
8.5
11
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
28.3
8.5
11
*
4AA12
NOMESCO Finland
NA
20.6
8.5
12
6
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
8.5
124
730
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
92.1
8.4
9
*
JFF13
NOMESCO Finland
Terminal enterostomy
92.1
8.4
9
*
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
92.1
8.4
9
*
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
13.2
8.4
14
11
4AA33
NOMESCO Finland
NA
+∞
8.4
8
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
8.4
8
*
TJK00
NOMESCO Finland
Intraoperative cholangiography
+∞
8.4
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
8.3
43
146
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
7.1
8.2
19
28
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
12.1
8.1
14
12
K90.0
ICD-10 Finland
Coeliac disease
6.6
8.1
20
32
4AB02
NOMESCO Finland
NA
34.2
8.1
10
*
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
34.2
8.1
10
*
B01AB05
ATC
enoxaparin; parenteral
2.2
8.1
95
507
XX3DW
NOMESCO Finland
Time consuming IT work
3.2
8.0
42
144
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
13.4
7.9
13
10
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.2
7.9
18
26
M81.9
ICD-10 Finland
Osteoporosis, unspecified
11.1
7.9
14
13
XF400
NOMESCO Finland
ECG with 12 standard connections
2.5
7.8
62
274
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
46.0
7.7
9
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
46.0
7.7
9
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
18.8
7.6
11
6
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
7.4
75
374
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
11.2
7.4
13
12
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.6
7.4
32
95
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
7.3
7
*
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
+∞
7.3
7
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
7.3
7
*
5761A
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SUPPURATIVA]
+∞
7.3
7
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
7.3
7
*
WX892
NOMESCO Finland
Monitored bed care
3.5
7.2
33
102
K56.0
ICD-10 Finland
Paralytic ileus
30.7
7.2
9
*
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
30.7
7.2
9
*
M05BA04
ATC
alendronic acid; oral
4.9
7.2
22
47
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
7.1
54
231
UJG02
NOMESCO Finland
Proctoscopy
7.2
7.1
16
23
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
7.1
60
275
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
7.0
78
404
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
11.2
6.8
12
11
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
11.2
6.8
12
11
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
9.6
6.8
13
14
H26.3
ICD-10 Finland
Drug-induced cataract
40.8
6.8
8
*
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
40.8
6.8
8
*
R4190
NOMESCO Finland
Nutritional therapy
4.6
6.8
22
50
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
17.1
6.8
10
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
6.7
31
97
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.8
6.7
21
46
K81.9
ICD-10 Finland
Cholecystitis, unspecified
23.0
6.7
9
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
8.0
6.7
14
18
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
8.9
6.6
13
15
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.6
6.5
14
19
K51.4
ICD-10 Finland
Inflammatory polyps
71.1
6.4
7
*
ZXE70
NOMESCO Finland
Moren than 15 and less than 18 hours
71.1
6.4
7
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
71.1
6.4
7
*
UJD02
NOMESCO Finland
Gastroscopy
4.4
6.4
22
53
M81.8
ICD-10 Finland
Other osteoporosis
18.4
6.3
9
5
ZXC86
NOMESCO Finland
Use of endoscopic device
18.4
6.3
9
5
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
+∞
6.3
6
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
6.3
6
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
6.3
6
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
6.3
6
*
RS122
NOMESCO Finland
NA
+∞
6.3
6
*
A07EC03
ATC
olsalazine; oral
+∞
6.3
6
*
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
XW000
NOMESCO Finland
Bone marrow biopsy
4.6
6.3
20
45
WX004
NOMESCO Finland
Patient-controlled sedation
27.2
6.3
8
*
ZX108
NOMESCO Finland
Inhalation
27.2
6.3
8
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
27.2
6.3
8
*
C03DA01
ATC
spironolactone; oral
3.1
6.2
33
115
WW500
NOMESCO Finland
Blood transfusion
4.8
6.2
19
41
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.9
6.2
13
17
E86
ICD-10 Finland
Volume depletion
6.9
6.1
14
21
WZC30
NOMESCO Finland
Teaching
2.5
6.1
48
210
A04AA02
ATC
granisetron; systemic, transdermal
3.9
6.0
23
62
Mortality – FinRegistry
↥Association
Association between endpoint K11_PSC_COLITIS_STRICT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PSC_COLITIS_STRICT | 2.174 [1.71, 2.76] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 793 males with K11_PSC_COLITIS_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have K11_PSC_COLITIS_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.422% |
| 5 | No data | 2.357% |
| 10 | No data | 5.82% |
| 15 | No data | 11.196% |
| 20 | No data | 19.291% |
Relationships between endpoints
↥Index endpoint: K11_PSC_COLITIS_STRICT – Colitis, primary sclerosing, strict definition
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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