colitis: Inflammation of the colon.
Colitis, primary sclerosing, strict definition
DOID EFO Endpoint Browser PheWeb
K11_PSC_COLITIS_STRICT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
2593 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
406 |
6. Filter based on genotype QC (FinnGen only) |
400 |
Control definitions (FinnGen only)
- Control conditions
- not K11_CHOLANGI
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Colitis, primary sclerosing, strict definition
based on the number of shared cases.
Similar with more cases:
- Colitis, primary sclerosing
- Cholangitis (primary sclerosing, PSC)
- Mucosal proctocolitis
- Ulcerative colitis
- Inflammatory bowel disease
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1356 | 487 | 865 |
| Only index persons | 1293 | 469 | 824 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 36.00 | 36.74 | 35.48 |
| Only index persons | 35.04 | 36.02 | 34.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 400 | 181 | 219 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.10 |
| Median age at first event (years) | 37.32 | 37.14 | 37.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 406
- Matched controls
- 4060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
1045.0
322.6
275
8
K51.5
ICD-10 Finland
Left sided colitis
14852.1
307.7
405
57
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
818.0
307.7
385
89
A05AA02
ATC
ursodeoxycholic acid; oral
1386.4
307.7
352
19
A07EC02
ATC
mesalazine; oral, rectal
585.5
307.7
381
103
K83.0
ICD-10 Finland
Cholangitis
+∞
307.7
404
*
UJF30
NOMESCO Finland
Ileoscopy through colon
43.0
307.7
273
185
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
51.8
307.7
299
208
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
220.3
307.7
296
49
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
213.4
307.3
149
11
L04AX01
ATC
azathioprine; systemic
52.8
296.6
186
64
K51.8
ICD-10 Finland
Other ulcerative colitis
104.9
296.1
156
24
UJK02
NOMESCO Finland
ERCP
102.8
291.6
154
24
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
171.1
291.3
144
13
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
86.7
286.6
156
29
UJF32
NOMESCO Finland
Coloscopy
37.8
277.5
338
472
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
84.8
270.0
147
27
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
26.1
243.6
214
166
A07EA06
ATC
budesonide; oral, local oral
36.3
225.0
155
68
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
67.3
206.2
116
24
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
114.0
186.7
96
11
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
97.5
173.4
91
12
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
50.1
170.6
102
27
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
42.2
155.2
97
30
WX404
NOMESCO Finland
Intravenous generell anesthesy
11.7
142.8
246
473
WX402
NOMESCO Finland
General anaesthesia
10.8
133.7
241
483
A07EA02
ATC
hydrocortisone; rectal
31.4
130.2
89
36
K51
ICD-10 Finland
Ulcerative colitis
54.3
117.4
68
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
9.4
116.6
247
577
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
63.8
107.3
60
11
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
52.1
106.3
62
14
K50.8
ICD-10 Finland
Other Crohn disease
33.2
101.4
67
24
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.1
94.6
149
244
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
93.4
86
*
J01MA12
ATC
levofloxacin; systemic
7.8
88.8
170
343
K50.1
ICD-10 Finland
Crohn disease of large intestine
39.6
88.2
55
16
127
Kela drug reimbursment
Transplant complication
38.8
86.1
54
16
ZXE00
NOMESCO Finland
One hour or less
7.4
83.7
287
1001
K50.9
ICD-10 Finland
Crohn disease, unspecified
25.9
83.4
60
27
L01BB02
ATC
mercaptopurine; oral
29.4
81.7
56
22
ZX120
NOMESCO Finland
Intravenous
9.8
80.9
110
149
P01AB01
ATC
metronidazole; oral, rectal
7.1
80.4
288
1034
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.5
79.4
213
588
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
10.4
76.9
97
119
K76.9
ICD-10 Finland
Liver disease, unspecified
29.0
74.3
51
20
H02AB07
ATC
prednisone; oral
7.5
72.0
128
234
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
116.5
71.8
76
8
ZXD10
NOMESCO Finland
Scheduled procedure
5.9
70.0
256
906
L04AD01
ATC
ciclosporin; systemic
25.8
69.8
50
22
WX002
NOMESCO Finland
Sedation and analgesia
6.3
68.5
159
377
TPH04
NOMESCO Finland
Cathetrisation of vein
6.0
68.1
175
455
H02AB06
ATC
prednisolone; systemic
6.3
67.2
296
1214
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
26.4
66.3
47
20
K83.1
ICD-10 Finland
Obstruction of bile duct
93.3
64.4
70
9
L04AA06
ATC
mycophenolic acid; systemic
23.5
62.0
46
22
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
+∞
61.0
57
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
22.9
60.1
45
22
Z94.4
ICD-10 Finland
Liver transplant status
172.0
57.6
59
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
9.8
57.5
73
89
Z2221
NOMESCO Finland
Medical doctor
4.9
56.1
205
697
K50.0
ICD-10 Finland
Crohn disease of small intestine
23.9
55.8
41
19
WX302
NOMESCO Finland
Thoracal epidural anesthesy
11.1
55.4
63
66
J01MA02
ATC
ciprofloxacin; systemic
4.8
54.9
240
933
JJC00
NOMESCO Finland
Allogenic transplantation of liver
310.6
54.6
54
*
A07EC01
ATC
sulfasalazine; oral, rectal
7.6
53.3
86
139
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
155.2
52.2
54
*
JN4CD
NOMESCO Finland
Very extensive body CT
15.2
49.3
45
33
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.5
46.3
65
89
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
94.9
46.0
50
6
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
19.3
46.0
37
21
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
12.0
45.2
48
45
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
488.7
45.2
44
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
488.7
45.2
44
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.7
44.2
97
211
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
476.2
44.1
43
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
6.2
43.4
85
166
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
164.0
42.7
44
*
WVA20
NOMESCO Finland
Medicine administration
13.3
42.6
42
35
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
14.2
42.3
40
31
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
159.8
41.6
43
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
426.7
39.8
39
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
116.8
39.5
42
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
9.5
39.0
49
58
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
147.5
38.5
40
*
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
10.5
36.5
42
44
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
64.9
35.9
41
7
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
9.1
35.8
46
56
R50.9
ICD-10 Finland
Fever, unspecified
4.3
35.2
116
348
UJF92
NOMESCO Finland
Capsular endoscopy
15.0
35.2
32
23
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
+∞
34.9
33
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
83.8
34.5
38
5
H02AB04
ATC
methylprednisolone; systemic
4.7
34.0
94
246
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
33.3
223
1061
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
10.9
33.2
37
37
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
173.2
31.1
32
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
30.6
29
*
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
54.5
29.9
35
7
L04AD02
ATC
tacrolimus; systemic
40.5
29.9
37
10
L04AB04
ATC
adalimumab; parenteral
10.0
29.6
35
38
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.3
29.1
45
68
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
7.0
28.9
47
75
TPH07
NOMESCO Finland
Cathetrisation of artery
4.8
28.6
72
173
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
28.5
27
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
28.2
150
609
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
155.7
28.0
29
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
51.1
27.9
33
7
C10AC01
ATC
colestyramine; oral
10.1
27.4
32
34
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.9
27.3
53
101
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
44.8
27.2
33
8
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.9
26.4
94
293
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.6
26.3
32
36
JJ5AT, ,
NOMESCO Finland
277.3
26.0
26
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
46.1
24.9
30
7
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
24.2
23
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.9
23.6
45
84
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.9
23.4
30
36
A07EA01
ATC
prednisolone; oral, rectal
38.9
23.3
29
8
N02AX02
ATC
tramadol; systemic, rectal
2.8
23.2
203
1063
L04AA01
ATC
[U] ciclosporin
42.9
23.0
28
7
L04AC05
ATC
ustekinumab; parenteral
55.3
22.4
26
5
D94
ICPC
Chronic enteritis/ulcerative colitis
37.4
22.4
28
8
3AC01, ,
NOMESCO Finland
41.2
22.0
27
7
UJF02
NOMESCO Finland
Peroral enteroscopy
46.1
21.7
26
6
JAH00
NOMESCO Finland
Laparotomy
9.0
21.2
27
32
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
23.0
21.1
30
14
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
21.1
192
1014
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.6
21.0
42
82
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
81.2
20.9
23
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.0
20.8
67
193
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
220.9
20.8
21
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.4
20.7
57
146
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
44.3
20.7
25
6
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
23.9
20.7
29
13
A07DA03
ATC
loperamide; oral
8.4
20.3
27
34
H02AB09
ATC
hydrocortisone; systemic
8.1
20.2
28
37
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
24.0
19.3
27
12
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.0
19.1
103
410
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
15.2
18.9
31
22
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
40.5
18.8
23
6
K85.8
ICD-10 Finland
Other acute pancreatitis
31.8
18.5
24
8
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.8
18.3
44
101
3042, ,
Kela drug reimbursment
69.9
17.9
20
*
253, ,
Kela drug reimbursment
69.9
17.9
20
*
WX419
NOMESCO Finland
Other general anesthesy
16.9
17.3
27
17
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
27.0
17.1
23
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
16.9
57
169
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
16.8
16
*
A07AA11
ATC
rifaximin; oral
177.0
16.6
17
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.8
15.5
36
80
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
15.3
76
286
R4110
NOMESCO Finland
Physiotherapy
2.5
15.1
130
648
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
15.0
71
260
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
83.2
14.7
16
*
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
14.7
14
*
1370
FHL
Colonoscopy, whole colon
37.5
14.6
18
5
A02BC02
ATC
pantoprazole; systemic
2.4
14.5
278
1942
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
14.4
112
532
Z2446
NOMESCO Finland
Social worker
3.6
14.3
50
151
K92.1
ICD-10 Finland
Melaena
5.1
14.3
31
65
Z93.2
ICD-10 Finland
Ileostomy status
44.2
14.2
17
*
JFF10
NOMESCO Finland
Loop enterostomy
31.3
14.0
18
6
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
24.8
13.9
19
8
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
13.6
13
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
144.6
13.5
14
*
B01AB05
ATC
enoxaparin; parenteral
2.4
13.4
124
634
K90.0
ICD-10 Finland
Coeliac disease
6.0
13.4
24
42
JN4AD
NOMESCO Finland
Body CT examination
3.5
13.4
49
153
WW500
NOMESCO Finland
Blood transfusion
5.5
13.1
26
50
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.3
13.1
35
87
WZC00
NOMESCO Finland
Treatment plan or consultation
2.2
13.1
166
968
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
13.0
45
135
R4190
NOMESCO Finland
Nutritional therapy
4.5
12.7
32
76
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
72.2
12.7
14
*
A07AA09
ATC
vancomycin; oral
18.0
12.6
19
11
K83.3
ICD-10 Finland
Fistula of bile duct
134.0
12.5
13
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
38.8
12.3
15
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
18.8
12.2
18
10
Z3226
NOMESCO Finland
Physiotherapist
2.5
12.1
88
402
JKA20
NOMESCO Finland
Cholecystectomy
9.4
11.9
24
27
TK800
NOMESCO Finland
Hemodialysis
10.1
11.9
23
24
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
19.6
11.7
17
9
256, ,
Kela drug reimbursment
66.9
11.7
13
*
L04AA33
ATC
[U] vedolizumab
66.9
11.7
13
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.7
11.6
27
60
D64.9
ICD-10 Finland
Anaemia, unspecified
3.5
11.6
42
130
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
123.4
11.5
12
*
XW000
NOMESCO Finland
Bone marrow biopsy
5.6
11.5
22
41
ZXD05
NOMESCO Finland
Urgent procedure
2.2
11.4
137
773
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.6
11.3
39
117
TJF80
NOMESCO Finland
Ostomy education
25.9
11.2
15
6
K85
ICD-10 Finland
Acute pancreatitis
10.5
11.1
21
21
SPAT1255
SPAT
Intravenous administration of medicine
3.9
11.1
33
89
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
16.1
10.9
17
11
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.3
10.7
23
29
130
Kela drug reimbursment
Malignant tumour
3.5
10.7
39
121
K75.4
ICD-10 Finland
Autoimmune hepatitis
61.7
10.7
12
*
A02BC01
ATC
omeprazole; systemic
2.2
10.7
111
590
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
14.7
10.6
17
12
M05BA04
ATC
alendronic acid; oral
4.5
10.5
26
61
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
+∞
10.5
10
*
UJG02
NOMESCO Finland
Proctoscopy
9.2
10.4
21
24
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
33.5
10.4
13
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
10.4
147
878
E86
ICD-10 Finland
Volume depletion
11.0
10.4
19
18
C03DA01
ATC
spironolactone; oral
3.1
10.3
46
162
K56.7
ICD-10 Finland
Ileus, unspecified
12.6
9.9
17
14
K56.0
ICD-10 Finland
Paralytic ileus
26.8
9.9
13
5
4AA12, ,
NOMESCO Finland
26.8
9.9
13
5
JN4BD
NOMESCO Finland
Extensive body CT
3.0
9.9
46
166
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.7
9.8
22
30
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
56.4
9.7
11
*
WZC30
NOMESCO Finland
Teaching
2.5
9.6
68
305
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
9.6
100
530
XF400
NOMESCO Finland
ECG with 12 standard connections
2.5
9.5
68
306
XX3DW
NOMESCO Finland
Time consuming IT work
2.8
9.5
51
199
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
18.1
9.5
14
8
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
102.3
9.5
10
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
7.2
9.4
22
32
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
9.4
98
518
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.1
9.4
20
41
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
9.4
9
*
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
+∞
9.4
9
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.9
9.2
27
72
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
37.6
9.1
11
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
37.6
9.1
11
*
4AB02, ,
NOMESCO Finland
37.6
9.1
11
*
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
19.1
9.0
13
7
XX2RW, ,
NOMESCO Finland
9.8
8.9
17
18
M81.9
ICD-10 Finland
Osteoporosis, unspecified
7.6
8.5
19
26
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
91.9
8.4
9
*
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
91.9
8.4
9
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
8.4
8
*
WX600
NOMESCO Finland
Single shot through catheter
9.7
8.3
16
17
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
8.3
68
325
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
12.0
8.1
14
12
ZX108
NOMESCO Finland
Inhalation
17.6
8.1
12
7
JFF13
NOMESCO Finland
Terminal enterostomy
34.1
8.1
10
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.6
8.1
48
197
M81.8
ICD-10 Finland
Other osteoporosis
22.5
8.1
11
5
ZXC86
NOMESCO Finland
Use of endoscopic device
22.5
8.1
11
5
H26.3
ICD-10 Finland
Drug-induced cataract
22.5
8.1
11
5
A41.9
ICD-10 Finland
Sepsis, unspecified
4.6
8.0
19
43
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.6
8.0
19
43
K81.0
ICD-10 Finland
Acute cholecystitis
8.7
7.9
16
19
WX872
NOMESCO Finland
Intensive care
3.7
7.8
25
71
B01AB04
ATC
dalteparin; parenteral
3.6
7.7
25
72
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.6
7.7
46
190
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
18.8
7.6
11
6
D97
ICPC
Liver disease NOS
25.6
7.6
10
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
81.5
7.4
8
*
4AA33, ,
NOMESCO Finland
81.5
7.4
8
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
81.5
7.4
8
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
81.5
7.4
8
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
7.4
20
50
WX892
NOMESCO Finland
Monitored bed care
2.8
7.4
37
139
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
7.4
25
74
R18
ICD-10 Finland
Ascites
11.1
7.3
13
12
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
7.3
7
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
7.3
7
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
7.3
7
*
5761A
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SUPPURATIVA]
+∞
7.3
7
*
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
+∞
7.3
7
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
7.3
7
*
B03BA03
ATC
hydroxocobalamin; parenteral
4.1
7.2
20
51
JJA20
NOMESCO Finland
Open biopsy of liver
30.6
7.2
9
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
20.4
7.2
10
5
K81.9
ICD-10 Finland
Cholecystitis, unspecified
20.4
7.2
10
5
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
3.6
7.1
23
66
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
7.2
7.1
16
23
C03CA01
ATC
furosemide; systemic
2.1
7.0
72
376
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.7
7.0
22
62
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
7.7
7.0
15
20
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.7
7.0
15
20
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
14.1
6.9
11
8
RS220, ,
NOMESCO Finland
9.5
6.8
13
14
UJD02
NOMESCO Finland
Gastroscopy
3.3
6.8
25
78
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
40.7
6.8
8
*
L04AG05
ATC
vedolizumab; parenteral
40.7
6.8
8
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
17.0
6.8
10
6
N02AA05
ATC
oxycodone; systemic
2.3
6.7
56
269
WX004
NOMESCO Finland
Patient-controlled sedation
22.9
6.7
9
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.1
6.7
18
45
Z3231
NOMESCO Finland
Registered nurse
1.8
6.5
111
690
E0000UV, ,
ATC
1.7
6.5
165
1152
6419
FHL
Other measure in this category
70.9
6.4
7
*
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
70.9
6.4
7
*
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
70.9
6.4
7
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
14.6
6.4
10
7
B07.9
ICD-10 Finland
Verruca simplex
3.3
6.4
24
76
K80.8
ICD-10 Finland
Other cholelithiasis
6.7
6.4
15
23
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.1
6.4
16
27
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
6.3
301
3413
A04AA02
ATC
granisetron; systemic, transdermal
3.0
6.3
27
93
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
6.3
6
*
L04AA10
ATC
[U] sirolimus
+∞
6.3
6
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
27.1
6.2
8
*
L01BC06
ATC
capecitabine; oral
3.7
6.1
19
53
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
6.2
6.1
15
25
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
6.2
6.1
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
233
64
84.09
307.65
3.1
1.3
0.87
0.63
g/l
1.51
216
51
331
223
75.94
307.65
8.2
4.5
2.45
26.10
ug/l
0.66
265
183
238
19
301.30
307.65
2.7
1.1
—
—
—
0
0
161
16
166.09
307.65
1.9
1.3
11.16
10.69
umol/l
0.19
161
16
298
87
126.01
307.65
7.6
3.0
38.34
1654.81
u/ml
0.50
278
73
229
36
144.62
307.65
2.8
1.0
—
—
—
0
0
283
256
34.19
303.93
4.4
2.2
12.80
10.02
g/l
18.59
271
235
165
32
86.18
301.50
1.9
1.1
197.00
—
titre
—
10
0
263
210
33.72
301.01
3.4
1.5
1.23
1.21
g/l
0.05
257
195
247
360
15.97
184.92
12.0
2.1
8.37
8.13
umol/l
0.06
236
315
322
770
16.38
158.81
18.0
3.6
96.74
93.83
%
1.32
316
756
370
1170
25.39
138.66
20.8
8.8
1.08
1.17
inr
2.51
134
371
362
1155
20.69
132.62
16.4
3.1
37.31
31.51
u/l
3.82
354
1109
148
185
12.02
118.63
2.4
1.5
—
—
—
0
0
99
64
20.13
118.62
6.2
5.1
858.22
542.20
iu/ml
—
18
10
192
339
9.85
116.67
2.9
2.3
22.31
24.77
%
1.13
180
296
271
728
9.19
110.83
3.6
1.3
2.50
2.26
g/l
1.88
258
472
189
363
8.87
105.35
3.0
2.3
2.46
2.44
g/l
0.14
181
338
194
400
8.37
100.71
3.0
2.3
12.65
14.45
umol/l
2.16
187
373
55
18
35.19
85.22
1.2
1.1
—
—
—
0
0
64
35
21.52
82.00
1.4
1.3
—
—
—
0
0
365
1636
13.19
80.70
18.8
6.6
0.19
0.19
e9/l
0.02
355
1461
221
628
6.53
79.87
4.6
2.0
3.21
2.97
mg/l
0.55
201
544
362
1650
12.02
77.17
18.3
6.1
1.80
1.92
e9/l
1.50
352
1487
265
928
6.34
74.54
6.2
2.4
74.54
61.35
u/l
0.76
255
872
80
83
11.76
71.35
1.4
1.3
365.11
190.56
u/ml
2.16
44
48
82
89
11.29
70.85
1.4
1.3
—
—
—
0
0
308
1282
6.81
69.49
11.0
7.2
1.21
1.21
mmol/l
0.61
271
1119
291
1166
6.28
68.20
10.3
6.5
1.22
1.21
mmol/l
0.03
285
1084
81
97
10.18
64.93
5.4
4.5
1.48
1.29
mg/l
1.09
81
90
366
1853
10.90
64.45
22.9
9.5
3.52
4.04
e9/l
7.09
360
1619
49
25
22.15
64.33
3.5
1.4
0.83
1.04
g/l
1.39
49
25
68
75
10.69
57.69
1.3
1.4
115.33
91.50
u/ml
—
9
14
79
106
9.01
57.68
1.7
1.6
0.01
0.03
iu/ml
0.42
28
17
129
319
5.46
51.50
13.4
7.5
105.22
104.12
mmol/l
2.46
129
319
87
150
7.11
50.67
1.4
1.4
—
—
—
0
0
387
2305
15.51
50.67
11.8
3.6
14.82
9.17
mm/h
11.50
381
2141
291
1388
4.87
48.93
4.5
2.6
92.24
103.44
ug/l
0.67
285
1300
192
683
4.44
48.07
3.9
2.2
—
—
—
0
0
51
51
11.29
46.06
2.8
4.5
1393.67
3431.25
u/ml
—
6
8
100
243
5.13
39.95
3.4
2.9
—
—
—
0
0
37
28
14.44
39.61
1.1
1.4
—
—
—
0
0
271
1397
3.83
36.73
4.6
2.5
—
—
—
0
0
377
2512
8.01
34.59
16.3
2.9
114.21
42.92
u/l
18.78
372
2404
49
70
7.82
33.40
1.6
1.1
—
—
—
0
0
43
62
7.64
28.99
2.4
2.3
30.86
4.83
umol/l
3.72
38
44
116
399
3.67
28.35
3.7
2.6
30.69
29.70
s
0.89
116
391
39
55
7.74
26.76
5.3
3.6
53.23
56.13
%
0.49
39
55
141
571
3.25
26.34
3.3
2.3
6.35
4.81
e6/l
0.83
134
509
183
862
3.04
26.26
4.1
2.8
217.85
47.59
e6/l
0.40
156
660
79
221
4.20
25.77
3.1
2.3
67.26
74.82
ml/min/173m2
0.58
34
88
70
180
4.49
25.48
4.3
3.6
1.21
1.23
mmol/l
2.11
65
164
89
274
3.88
25.39
3.1
4.3
204.29
236.07
u/l
2.41
89
260
170
781
3.02
25.33
4.2
2.8
0.51
0.32
e6/l
0.44
145
586
140
581
3.15
24.89
2.5
1.9
1.47
1.45
%
0.14
128
536
29
31
10.00
24.69
1.0
1.1
—
—
—
0
0
116
443
3.27
23.59
2.9
2.6
2.26
2.18
e6/l
0.05
78
241
398
3330
10.90
22.23
48.1
11.2
16.75
21.24
mg/l
3.72
381
2527
109
416
3.21
22.04
2.4
1.8
—
—
—
0
0
35
55
6.87
21.73
5.5
3.2
4.03
4.08
e9/l
0.03
35
55
76
233
3.78
21.62
6.9
4.2
0.68
1.79
mmol/l
2.16
68
189
45
94
5.26
20.89
1.7
2.2
1.15
1.51
g/l
1.86
40
84
190
1008
2.66
20.55
4.1
2.8
—
—
—
0
0
29
16
19.40
19.39
3.1
4.3
8.75
8.89
mg/l
0.02
23
16
113
472
2.93
19.25
3.1
2.5
0.86
1.13
e6/l
0.37
77
270
50
126
4.39
18.50
16.7
16.6
—
—
—
0
0
188
1036
2.52
18.23
2.5
1.8
94.63
96.25
pmol/l
0.21
115
549
23
9
26.97
17.09
1.1
1.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
34
66
5.53
17.05
2.8
5.4
0.21
0.32
u/ml
1.64
16
39
49
137
3.93
15.73
1.8
1.6
—
—
—
0
0
24
36
7.02
15.47
1.3
1.2
—
—
—
0
0
382
3100
4.93
15.47
38.4
9.9
93.06
90.62
ml/min/173m2
1.18
360
2513
371
2963
3.92
15.14
50.2
13.9
13.82
14.37
%
3.49
371
2920
105
497
2.50
13.48
2.1
1.6
472.77
438.80
pmol/l
0.47
91
444
41
117
3.79
12.75
1.9
1.5
—
—
—
0
0
72
292
2.78
12.56
2.5
1.7
—
—
—
0
0
145
815
2.21
12.38
1.5
1.2
1.19
1.67
u/ml
0.38
38
230
72
295
2.75
12.31
2.5
1.8
—
—
—
0
0
67
267
2.81
12.06
16.1
11.4
-0.31
1.26
mmol/l
2.49
56
216
26
55
4.98
11.82
1.0
1.1
—
—
—
0
0
58
226
2.83
10.85
17.1
11.8
117.74
125.29
g/l
1.64
58
218
21
45
4.87
9.40
3.6
2.6
14.88
17.08
%
1.61
11
23
82
404
2.29
9.35
2.1
1.6
1219.34
1150.24
nmol/l
0.23
64
319
26
68
4.02
9.11
2.3
1.4
—
—
—
0
0
14
10
14.44
8.75
2.1
1.7
1.74
1.85
umol/l
—
14
10
126
755
1.97
8.54
4.6
2.5
358.11
6605.45
umol/l
3.07
120
683
12
6
20.55
8.51
1.0
1.0
—
—
—
0
0
26
75
3.64
7.95
2.5
1.4
—
—
—
0
0
15
17
9.11
7.61
1.3
2.1
—
1224630.00
—
0
5
209
1531
1.75
7.11
4.9
4.3
0.00
0.00
estimate
-0.00
62
297
209
1533
1.75
7.06
3.7
3.1
0.00
0.00
estimate
0.50
61
307
211
1552
1.75
7.05
3.7
3.1
0.00
0.01
estimate
0.50
63
284
12
11
11.20
6.84
2.4
1.5
26.67
28.64
umol/l
0.15
12
11
80
440
2.02
6.77
5.0
2.7
2.46
2.43
mmol/l
1.27
74
388
16
39
4.23
6.14
2.0
1.5
—
—
—
0
0
22
68
3.36
6.09
1.3
1.4
246.75
292.66
ug/g
0.39
13
40
19
55
3.58
5.80
1.6
1.4
—
—
—
0
0
19
55
3.58
5.80
1.6
1.4
—
—
—
0
0
120
804
1.70
5.29
4.3
3.3
0.00
0.00
estimate
0.50
61
286
12
18
6.83
5.29
1.2
1.0
1212.17
1519.78
miu/ml
0.51
12
18
27
104
2.71
5.17
1.3
1.1
—
—
—
0
0
27
105
2.68
5.08
1.3
1.1
—
—
—
0
0
17
51
3.44
4.94
2.6
1.8
—
—
—
0
0
39
184
2.24
4.88
3.4
3.5
1.47
1.45
mmol/l
0.01
24
135
16
38
4.34
4.87
2.0
1.5
—
—
—
0
0
16
38
4.34
4.87
2.0
1.5
—
—
—
0
0
16
38
4.34
4.87
2.0
1.5
—
—
—
0
0
16
38
4.34
4.87
1.9
1.5
—
—
—
0
0
16
38
4.34
4.87
2.0
1.5
—
—
—
0
0
83
512
1.78
4.87
3.6
3.4
19.07
279.26
ng/l
2.71
58
352
18
58
3.20
4.69
2.2
3.9
29.95
28.69
mg/l
0.09
11
47
18
58
3.20
4.69
2.2
3.9
36.47
150.68
mg/l
0.55
11
48
13
26
5.13
4.67
2.2
1.3
31.92
33.81
pg
0.78
13
26
16
48
3.43
4.65
1.8
1.6
—
—
—
0
0
21
75
2.90
4.62
2.2
2.3
12.62
10.03
g/l
1.05
21
69
105
703
1.67
4.57
2.4
1.9
1.74
0.96
mg/l
1.25
85
520
15
36
4.29
4.56
1.7
1.5
—
—
—
0
0
307
2646
1.66
4.54
3.7
3.4
—
—
—
0
0
8
8
10.17
4.54
1.4
1.5
—
—
—
0
0
22
82
2.78
4.49
2.1
2.2
—
—
—
0
0
22
82
2.78
4.49
2.1
2.2
7.17
7.17
g/l
0.00
22
77
22
82
2.78
4.49
2.1
2.2
3.87
3.57
g/l
0.78
22
77
363
3286
1.99
4.47
6.3
3.9
4.60
4.72
mmol/l
1.73
354
3107
143
1040
1.58
4.43
3.7
3.0
22.53
34.05
ng/l
0.85
89
609
9
12
7.64
4.37
1.1
2.1
—
—
—
0
0
33
156
2.21
4.13
1.5
1.4
—
—
—
0
0
10
19
5.37
3.85
1.6
1.3
—
—
—
0
0
12
28
4.38
3.84
1.2
1.1
—
—
—
0
0
12
28
4.38
3.84
1.2
1.1
—
—
—
0
0
399
3835
3.34
3.44
61.5
16.5
40.04
41.39
%
6.94
391
3652
18
70
2.64
3.43
2.3
2.2
37.57
39.55
g/l
0.76
18
65
8
14
5.80
3.35
1.3
1.2
11.50
8.93
ug/l
—
8
14
19
79
2.47
3.18
2.2
2.2
3.26
2.91
g/l
1.18
19
74
154
1208
1.44
3.10
3.9
3.1
—
—
—
0
0
21
93
2.33
3.09
4.8
10.9
1.35
1.62
%
0.63
21
84
17
68
2.57
3.08
1.9
1.6
—
—
—
0
0
8
16
5.08
3.06
1.1
1.0
—
—
—
0
0
9
21
4.36
3.01
2.3
1.5
—
—
—
0
0
17
69
2.53
3.00
1.9
1.7
—
—
—
0
0
22
101
2.25
2.99
2.3
1.9
—
—
—
0
0
21
96
2.25
2.88
2.1
1.8
—
—
—
0
0
7
13
5.46
2.88
1.7
2.1
206.86
131.69
%
—
7
13
8
18
4.51
2.81
1.8
3.3
5039.13
765.56
u/ml
—
8
18
36
204
1.84
2.80
1.4
1.2
—
—
—
0
0
7
14
5.07
2.74
4.9
3.0
—
—
—
0
0
7
14
5.07
2.74
1.1
1.0
—
—
—
0
0
14
55
2.60
2.64
1.4
1.8
5.23
5.20
mmol/24h
0.01
14
49
9
25
3.66
2.59
2.0
2.0
—
—
—
0
0
24
123
2.01
2.51
1.6
2.3
—
—
—
0
0
13
51
2.60
2.46
1.1
1.2
—
—
—
0
0
13
51
2.60
2.46
1.8
1.8
—
—
—
0
0
13
51
2.60
2.46
1.8
1.8
—
—
—
0
0
6
12
5.06
2.41
1.7
1.7
—
—
—
0
0
5
8
6.31
2.38
2.0
1.9
16.80
14.38
u/l
—
5
8
35
556
0.59
2.29
2.3
2.5
0.82
0.69
ug/l
0.20
20
300
11
40
2.80
2.29
2.0
1.6
—
—
—
0
0
6
13
4.67
2.28
2.2
1.5
—
—
—
0
0
6
13
4.67
2.28
2.0
1.5
—
—
—
0
0
9
29
3.15
2.24
1.8
1.6
—
—
—
0
0
114
892
1.39
2.22
3.2
3.1
8.69
8.68
mmol/l
0.01
105
786
10
35
2.90
2.22
1.6
1.5
—
—
—
0
0
17
80
2.17
2.22
1.8
2.5
—
—
—
0
0
23
122
1.94
2.21
5.8
2.9
0.73
0.65
%
0.43
23
122
9
32
2.85
2.01
2.2
1.7
—
—
—
0
0
9
32
2.85
2.01
2.2
1.7
—
—
—
0
0
12
52
2.35
1.89
1.5
1.7
—
—
—
0
0
11
46
2.43
1.86
2.9
2.4
—
—
—
0
0
0
54
0.00
1.86
0.0
1.5
—
20.94
—
0
48
6
17
3.57
1.84
2.0
2.6
37133.33
35088.24
ug/l
—
6
17
24
138
1.79
1.84
1.3
1.4
243.12
277.97
miu/ml
0.15
11
69
9
35
2.61
1.81
1.4
1.6
—
—
—
0
0
12
54
2.26
1.75
1.3
1.5
—
—
—
0
0
55
748
0.69
1.75
2.8
3.6
21.47
22.01
%
0.07
14
278
7
24
2.95
1.73
3.7
2.0
—
—
—
0
0
5
13
3.88
1.72
1.0
1.3
—
—
—
0
0
5
13
3.88
1.72
2.2
1.5
—
—
—
0
0
5
13
3.88
1.72
2.2
1.5
—
—
—
0
0
266
2415
1.29
1.68
4.1
3.7
14.46
14.58
pmol/l
0.36
253
2227
8
31
2.61
1.66
1.5
1.1
—
—
—
0
0
8
31
2.61
1.66
1.5
1.1
—
—
—
0
0
5
14
3.60
1.62
1.6
1.4
89.40
69.68
ug/l
—
5
14
8
32
2.53
1.60
1.5
1.1
—
—
—
0
0
8
32
2.53
1.60
1.5
1.1
—
—
—
0
0
8
32
2.53
1.60
1.5
1.1
—
—
—
0
0
94
751
1.33
1.57
4.0
3.9
10.18
9.29
mg/mmol
0.07
63
497
5
15
3.36
1.53
1.0
1.3
—
—
—
0
0
7
28
2.53
1.46
1.1
1.9
—
—
—
0
0
78
614
1.33
1.45
2.2
3.2
1313.56
754.59
ng/l
0.59
68
501
22
134
1.68
1.42
1.5
1.4
5.06
7.62
u/l
1.15
16
111
20
120
1.70
1.37
1.6
1.7
—
—
—
0
0
0
38
0.00
1.35
0.0
1.1
—
—
—
0
0
21
321
0.64
1.22
10.3
5.8
—
—
—
0
0
7
32
2.21
1.08
1.1
1.1
—
—
—
0
0
5
22
2.29
1.03
1.2
1.4
1.55
1.50
g/l
—
5
22
12
68
1.79
1.01
1.2
1.2
—
—
—
0
0
7
35
2.02
1.00
1.0
1.1
—
—
—
0
0
34
251
1.39
0.97
1.1
1.3
97.99
141.93
iu/ml
—
9
110
12
69
1.76
0.97
1.1
1.2
—
1.03
—
0
6
6
27
2.24
0.94
1.0
1.6
—
—
—
0
0
309
2938
1.22
0.92
4.6
4.3
1.93
2.22
mu/l
0.32
294
2744
15
94
1.62
0.92
1.2
1.2
—
2.96
—
0
11
340
3271
1.24
0.86
5.3
3.8
1.53
1.41
mmol/l
4.98
331
3083
12
73
1.66
0.82
1.1
1.2
—
—
—
0
0
19
130
1.48
0.82
3.2
3.6
23.47
24.83
mmol/l
1.70
19
124
330
3173
1.21
0.79
4.9
3.5
1.20
1.32
mmol/l
2.68
319
2980
20
278
0.70
0.77
1.6
1.9
—
—
—
0
0
5
24
2.10
0.74
1.0
1.0
—
—
—
0
0
5
24
2.10
0.74
1.4
1.1
—
—
—
0
0
7
39
1.81
0.73
1.0
1.4
—
—
—
0
0
343
3318
1.22
0.72
5.4
4.2
2.69
2.87
mmol/l
4.00
332
3120
7
41
1.72
0.70
1.0
1.9
—
—
—
0
0
10
61
1.66
0.69
1.2
1.1
—
—
—
0
0
5
93
0.53
0.67
1.8
1.8
—
—
—
0
0
36
445
0.79
0.65
1.2
1.6
—
—
—
0
0
8
49
1.65
0.62
1.1
1.5
—
—
—
0
0
5
30
1.67
0.61
1.2
1.8
—
—
—
0
0
5
30
1.67
0.61
1.2
1.8
—
—
—
0
0
5
30
1.67
0.61
1.2
1.8
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
1.08
—
0
13
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
9.2
—
53.78
—
0
9
6
35
1.72
0.58
1.0
1.9
—
—
—
0
0
20
150
1.35
0.57
14.8
11.4
23.33
24.59
mmol/l
0.87
20
140
17
227
0.74
0.55
1.5
1.5
—
—
—
0
0
15
200
0.74
0.49
1.0
1.0
—
—
—
0
0
5
82
0.60
0.46
1.6
1.5
—
—
—
0
0
28
338
0.82
0.44
1.6
2.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
7
101
0.69
0.40
1.4
1.6
—
—
—
0
0
10
136
0.73
0.38
1.6
1.5
—
—
—
0
0
11
146
0.75
0.36
1.4
1.4
—
—
—
0
0
9
71
1.27
0.36
1.0
1.1
—
—
—
0
0
14
108
1.31
0.35
1.2
1.4
—
—
—
0
0
9
125
0.71
0.35
1.4
1.4
—
—
—
0
0
9
125
0.71
0.35
1.4
1.4
—
—
—
0
0
9
126
0.71
0.35
1.4
1.4
—
—
—
0
0
9
126
0.71
0.35
1.4
1.4
—
—
—
0
0
62
684
0.89
0.34
1.7
2.3
—
—
—
0
0
6
45
1.34
0.34
1.3
1.5
179.78
187.54
pmol/l
—
6
45
56
621
0.89
0.33
1.6
2.1
—
—
—
0
0
7
54
1.30
0.30
1.0
1.3
36.86
10.69
u/l
—
7
49
7
94
0.74
0.22
1.4
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
23.08
—
0
13
0
14
0.00
0.20
0.0
1.0
—
6.66
—
0
14
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
13
110
1.19
0.17
1.2
1.1
—
—
—
0
0
80
829
0.96
0.11
1.7
1.5
—
—
—
0
0
287
2900
0.96
0.10
6.0
4.7
37.19
38.65
mmol/mol
2.04
277
2746
53
554
0.95
0.10
1.3
1.3
7.02
9.19
u/ml
0.14
19
226
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
6
56
1.07
0.08
1.0
1.4
—
—
—
0
0
20
186
1.08
0.07
2.3
1.9
—
—
—
0
0
310
3113
0.98
0.03
3.7
3.8
5.79
5.79
mmol/l
0.02
298
2891
50
489
1.03
0.03
1.5
1.4
—
—
—
0
0
58
571
1.02
0.02
1.3
1.3
18.35
25.83
iu/ml
0.55
20
184
17
168
1.01
0.00
2.5
2.7
2364.29
3050.08
u/l
—
8
70
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
77
0.91
-0.00
2.9
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
57.30
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_PSC_COLITIS_STRICT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PSC_COLITIS_STRICT | 2.174 [1.71, 2.76] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 793 males with K11_PSC_COLITIS_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have K11_PSC_COLITIS_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.422% |
| 5 | No data | 2.357% |
| 10 | No data | 5.82% |
| 15 | No data | 11.196% |
| 20 | No data | 19.291% |
Relationships between endpoints
↥Index endpoint: K11_PSC_COLITIS_STRICT – Colitis, primary sclerosing, strict definition
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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