Acquired haemolytic anaemia

D3_ACQHAEMOLYTICANAEMIA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D59
  • Cause of death: ICD-10 D59

2 out of 7 registries used, show all original rules.

843

4. Check minimum number of events

None

843

5. Include endpoints

907

6. Filter based on genotype QC (FinnGen only)

872

Control definitions (FinnGen only)

Control exclude
D3_HAEMOLYTICANAEMIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D55-D59
Name in latin
Anaemia haemolytica acquisita

Similar endpoints

List of similar endpoints to Acquired haemolytic anaemia based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7041 3819 3130
Only index persons 4923 2698 2225
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.09
Only index persons 0.09 0.10 0.08
Median age at first event (years)
Whole population 65.04 66.51 63.16
Only index persons 61.86 62.50 61.08

-FinnGen-

Key figures

All Female Male
Number of individuals 872 444 428
Unadjusted period prevalence (%) 0.18 0.16 0.20
Median age at first event (years) 62.40 57.58 67.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
907
Matched controls
9070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
+∞
307.7
428
*
D59.9
ICD-10 Finland
Acquired haemolytic anaemia, unspecified
+∞
297.8
269
*
XW000
NOMESCO Finland
Bone marrow biopsy
17.1
243.5
222
169
D64.9
ICD-10 Finland
Anaemia, unspecified
9.5
229.1
357
581
WW500
NOMESCO Finland
Blood transfusion
11.3
144.3
165
175
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.3
108.0
281
711
TK800
NOMESCO Finland
Hemodialysis
13.9
95.3
91
72
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
32.1
91.7
60
20
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.9
89.8
90
77
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
24.1
89.8
65
29
L04AA06
ATC
mycophenolic acid; systemic
15.4
87.1
78
55
ZX120
NOMESCO Finland
Intravenous
5.3
84.0
198
453
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.2
80.2
130
207
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
18.0
77.9
64
38
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
16.9
74.1
63
40
D59.4
ICD-10 Finland
Other nonautoimmune haemolytic anaemias
+∞
71.8
68
*
127
Kela drug reimbursment
Transplant complication
15.7
71.4
63
43
Z94.0
ICD-10 Finland
Kidney transplant status
21.2
71.0
54
27
B03XA02
ATC
darbepoetin alfa; parenteral
10.5
70.8
81
84
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
25.1
70.4
50
21
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
10.7
70.2
79
80
H02AB06
ATC
prednisolone; systemic
3.3
66.8
582
3160
Z49.1
ICD-10 Finland
Extracorporeal dialysis
15.5
64.4
57
39
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
27.2
63.8
44
17
D59.3
ICD-10 Finland
Haemolytic-uraemic syndrome
+∞
61.1
58
*
D59.8
ICD-10 Finland
Other acquired haemolytic anaemias
+∞
59.0
56
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.0
58.8
442
2158
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
10.5
55.7
63
64
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
54.3
384
1796
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.0
53.5
126
283
B03XA01
ATC
erythropoietin; parenteral
16.1
53.2
46
30
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
52.8
552
3162
N08.2*D59.3
ICD-10 Finland
Glomerular disorders in haemolytic-uraemic syndrome
+∞
51.6
49
*
D64.8
ICD-10 Finland
Other specified anaemias
10.0
51.2
60
64
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.1
51.0
117
257
L04AD02
ATC
tacrolimus; systemic
17.6
50.8
42
25
L04AD01
ATC
ciclosporin; systemic
11.2
50.1
54
51
A12AA04
ATC
calcium carbonate; oral
11.2
50.1
54
51
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
15.5
48.8
43
29
A11CC03
ATC
alfacalcidol; systemic
7.8
47.6
68
93
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.1
46.4
141
386
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
8.1
45.5
63
83
N18.0
ICD-10 Finland
End-stage renal disease
14.8
45.3
41
29
L04AX01
ATC
azathioprine; systemic
6.0
44.5
82
147
C03CA01
ATC
furosemide; systemic
2.6
43.5
409
2159
D59.0
ICD-10 Finland
Drug-induced autoimmune haemolytic anaemia
+∞
43.1
41
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
14.5
42.7
39
28
M04AA01
ATC
allopurinol; systemic
3.2
42.2
206
767
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
41.4
121
321
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
7.0
40.4
64
98
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
39.2
234
973
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
38.6
280
1287
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
38.5
172
605
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
14.5
38.4
35
25
JN4AD
NOMESCO Finland
Body CT examination
3.5
37.9
149
484
L04AA01
ATC
[U] ciclosporin
12.8
37.7
37
30
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.3
37.0
104
267
H02AB07
ATC
prednisone; oral
3.0
35.3
188
730
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.7
34.0
66
124
V03AE01
ATC
polystyrene sulfonate; oral
9.7
33.8
40
43
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.8
33.1
79
178
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
31.9
132
441
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
30.0
236
1111
UJF32
NOMESCO Finland
Coloscopy
2.3
29.6
300
1580
R50.9
ICD-10 Finland
Fever, unspecified
2.7
29.4
194
838
D70.89
ICD-10 Finland
Neutropenic splenomegaly
9.5
29.3
35
38
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
29.1
309
1658
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.7
28.7
69
156
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
10.0
28.7
33
34
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
9.1
28.2
35
40
A02BC02
ATC
pantoprazole; systemic
2.3
28.0
658
4828
B03BA03
ATC
hydroxocobalamin; parenteral
3.7
27.6
93
271
D59.5
ICD-10 Finland
Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
+∞
27.2
26
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.5
27.1
102
320
2839X
ICD-9 Finland
Acquired haemolytic anaemias, Acquired haemolytic anaemia, unspecified
+∞
26.2
25
*
WW400
NOMESCO Finland
Plasmaferesis
133.7
24.7
26
*
JN4BD
NOMESCO Finland
Extensive body CT
2.8
24.7
139
550
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
21.4
24.0
35
17
WW200
NOMESCO Finland
Immunization
5.4
23.8
48
93
ZXD05
NOMESCO Finland
Urgent procedure
2.1
23.4
322
1887
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
29.1
23.3
31
11
L03AA02
ATC
filgrastim; parenteral
4.8
23.2
53
115
2830A
ICD-9 Finland
Acquired haemolytic anaemias, Autoimmune haemolytic anaemias[ANAEMIA HAEMOLYTICA AUTOIMMUNISATORIA PRIMARIA]
+∞
23.0
22
*
B01AA03
ATC
warfarin; systemic
2.2
23.0
240
1261
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
7.7
22.6
32
43
1XC02, ,
NOMESCO Finland
22.1
22.2
32
15
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.7
22.0
28
33
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
25.8
21.9
30
12
N18.8
ICD-10 Finland
Other chronic renal failure
5.2
21.8
46
93
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.7
21.1
71
206
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.9
20.8
63
170
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.9
20.5
46
98
GD1AD
NOMESCO Finland
Thorax CT examination
3.3
20.5
81
261
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
20.0
84
281
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
20.0
234
1278
H02AB09
ATC
hydrocortisone; systemic
5.1
19.9
42
85
D59.6
ICD-10 Finland
Haemoglobinuria due to haemolysis from other external causes
+∞
19.9
19
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
6.4
19.8
33
53
TGC00
NOMESCO Finland
Bronchial lavation
4.6
19.6
48
110
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
6.9
19.2
30
45
Z3231
NOMESCO Finland
Registered nurse
2.0
19.2
289
1726
6BA02, ,
NOMESCO Finland
71.4
18.8
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
18.4
264
1546
V03AE02
ATC
sevelamer; oral
25.6
18.3
25
10
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
33.7
18.0
23
7
D59.2
ICD-10 Finland
Drug-induced nonautoimmune haemolytic anaemia
+∞
17.8
17
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.6
17.7
43
98
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.4
17.6
45
107
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
17.3
158
777
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
42.9
17.3
21
5
H02AB04
ATC
methylprednisolone; systemic
2.3
17.3
155
757
3AC01, ,
NOMESCO Finland
15.2
17.2
28
19
137
Kela drug reimbursment
Uraemia requiring dialysis
12.9
17.2
30
24
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.7
17.2
40
88
Z49.0
ICD-10 Finland
Preparatory care for dialysis
13.6
17.0
29
22
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.3
16.9
67
216
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
16.9
176
913
B82
ICPC
Anaemia other/unspecified
4.1
16.7
47
120
M31.1
ICD-10 Finland
Thrombotic microangiopathy
173.1
16.5
17
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
6.2
16.5
28
46
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
15.7
16.3
26
17
Z2221
NOMESCO Finland
Medical doctor
1.9
16.2
268
1636
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.5
16.1
58
176
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
26.8
15.6
21
8
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
15.6
248
1492
UJF92
NOMESCO Finland
Capsular endoscopy
5.1
15.6
33
67
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
5.9
15.5
28
49
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
38.8
15.4
19
5
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.8
15.1
81
311
A10AB05
ATC
insulin aspart; parenteral
2.6
14.9
89
360
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
6.9
14.9
23
34
B01AB10
ATC
tinzaparin; parenteral
2.4
14.8
111
500
M05BA04
ATC
alendronic acid; oral
2.5
14.8
102
443
L01AA02
ATC
chlorambucil; oral
21.5
14.7
21
10
L01AA01
ATC
cyclophosphamide; systemic
21.5
14.7
21
10
ZX108
NOMESCO Finland
Inhalation
12.1
14.6
26
22
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.7
14.5
46
128
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
14.3
55
174
J01MA12
ATC
levofloxacin; systemic
2.0
14.3
189
1065
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.8
14.1
44
121
SPAT1255
SPAT
Intravenous administration of medicine
2.7
14.1
76
292
B01AB05
ATC
enoxaparin; parenteral
1.8
14.1
309
2044
PJA10
NOMESCO Finland
Exploration of lymph nodes
6.0
14.0
25
43
I34.1
ICD-10 Finland
Mitral (valve) prolapse
3.9
14.0
41
108
JMA10
NOMESCO Finland
Transabdominal total splenectomy
12.9
13.9
24
19
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.5
13.9
49
147
J01MA02
ATC
ciprofloxacin; systemic
1.7
13.8
360
2497
A07AA09
ATC
vancomycin; oral
6.4
13.8
23
37
JN6AD
NOMESCO Finland
CT of torso and neck
5.4
13.8
27
51
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
13.8
105
477
A10AC01
ATC
insulin (human); parenteral
2.5
13.7
92
394
E87.5
ICD-10 Finland
Hyperkalaemia
4.6
13.6
32
71
B81
ICPC
Anaemia vit B12/folate deficiency
3.3
13.6
52
164
R4110
NOMESCO Finland
Physiotherapy
1.8
13.6
267
1707
WX892
NOMESCO Finland
Monitored bed care
2.5
13.5
90
384
SPAT1088
SPAT
Blood transfusion
16.5
13.5
21
13
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
13.5
171
948
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
13.5
119
575
J01MA14
ATC
moxifloxacin; systemic
2.4
13.4
98
436
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.7
13.4
42
116
J01FF01
ATC
clindamycin; systemic
1.8
13.4
253
1596
R06.0
ICD-10 Finland
Dyspnoea
1.8
13.4
267
1713
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
13.4
120
584
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
13.3
115
550
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
3.1
13.3
57
193
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
13.2
50
157
WX872
NOMESCO Finland
Intensive care
2.9
13.2
63
227
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
15.3
13.1
21
14
D53.1
ICD-10 Finland
Other megaloblastic anaemias, not elsewhere classified
28.8
13.0
17
6
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
28.8
13.0
17
6
C90.0
ICD-10 Finland
Multiple myeloma
6.2
13.0
22
36
ZXE00
NOMESCO Finland
One hour or less
1.7
12.9
360
2533
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
12.8
75
301
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
12.7
127
644
C07AB07
ATC
bisoprolol; oral
1.7
12.6
466
3524
196
Kela drug reimbursment
Paricalcitol and cinacalcet
17.6
12.5
19
11
28390
ICD-8 Finland
Acquired haemolytic anaemias, Autoimmunisatoria primaria
+∞
12.5
12
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
12.4
39
108
WX882
NOMESCO Finland
High dependency care
3.5
12.3
42
123
D50.8
ICD-10 Finland
Other iron deficiency anaemias
5.9
12.3
22
38
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.4
12.3
31
73
C09AA02
ATC
enalapril; systemic
1.9
12.2
197
1180
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.6
12.2
29
65
B05DB
ATC
Hypertonic solutions
12.6
12.2
21
17
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
12.1
124
635
Z49.2
ICD-10 Finland
Other dialysis
11.9
11.9
21
18
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
11.8
30
71
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
11.8
451
3418
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
30.5
11.7
15
5
122
Kela drug reimbursment
Aplastic anaemia
65.8
11.6
13
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
8.8
11.6
24
28
A05AA02
ATC
ursodeoxycholic acid; oral
4.9
11.5
25
52
28398
ICD-8 Finland
Acquired haemolytic anaemias, Aliae definitar
+∞
11.5
11
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.0
11.5
52
182
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
11.4
125
656
ZX112
NOMESCO Finland
Subcutaneous
3.9
11.3
33
87
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
12.9
11.2
19
15
C08CA05
ATC
nifedipine; systemic
2.5
11.1
71
297
Z2446
NOMESCO Finland
Social worker
2.4
11.1
80
354
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
11.1
186
1125
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
11.3
11.1
20
18
K92.1
ICD-10 Finland
Melaena
2.6
11.1
67
273
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.4
11.1
40
122
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
9.4
11.0
22
24
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
4.1
11.0
30
75
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
43.9
10.9
13
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
15.7
10.9
17
11
B05DA
ATC
Isotonic solutions
10.7
10.8
20
19
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
10.7
226
1459
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
28.4
10.7
14
5
L01XX52
ATC
venetoclax; oral
21.8
10.7
15
7
N19
ICD-10 Finland
Unspecified kidney failure
3.0
10.7
48
167
D64
ICD-10 Finland
Other anaemias
60.7
10.6
12
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.1
10.5
44
147
A04AA01
ATC
ondansetron; systemic, rectal
2.3
10.5
80
363
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
111.3
10.4
11
*
J05AB11
ATC
valaciclovir; oral
1.9
10.4
137
766
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
10.4
98
486
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
10.4
98
486
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
8.9
10.3
21
24
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
10.8
10.3
19
18
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
10.3
160
944
399
Kela drug reimbursment
Venetoclax
19.0
10.3
15
8
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.3
10.2
39
123
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
10.2
99
495
107
Kela drug reimbursment
Pernicious anaemia
4.2
10.2
27
66
TK810
NOMESCO Finland
Hemofiltration
13.3
10.2
17
13
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.8
10.2
51
189
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
10.1
357
2623
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
11.5
10.1
18
16
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.4
10.1
36
109
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
9.9
304
2158
A46
ICD-10 Finland
Erysipelas
1.9
9.9
137
778
R4190
NOMESCO Finland
Nutritional therapy
2.9
9.9
45
158
120
Kela drug reimbursment
Hypogammaglobulinaemia
26.3
9.8
13
5
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
26.3
9.8
13
5
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.3
9.7
25
60
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
9.7
239
1606
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
8.5
9.6
20
24
K83
ICPC
Heart valve disease NOS
7.2
9.5
22
31
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
15.2
9.5
15
10
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
30.4
9.4
12
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
30.4
9.4
12
*
C08CA01
ATC
amlodipine; oral
1.6
9.4
351
2604
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
9.4
323
2351
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
9.3
53
210
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
9.3
105
557
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.2
183
1158
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
4.0
9.2
26
67
N02AA05
ATC
oxycodone; systemic
1.7
9.1
171
1064
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.8
9.1
27
72
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
11.6
9.1
16
14
Z94.4
ICD-10 Finland
Liver transplant status
15.8
9.0
14
9
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
37.1
9.0
11
*
6753
FHL
Transabdominal splenectomy
37.1
9.0
11
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
37.1
9.0
11
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.4
9.0
61
263
H03AA01
ATC
levothyroxine sodium; systemic
1.7
8.9
200
1307
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
8.9
92
472
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.9
373
2831
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.2
8.8
34
108
B80
ICPC
Iron deficiency anaemia
3.5
8.8
30
88
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.3
8.8
32
98
K29.7
ICD-10 Finland
Gastritis, unspecified
2.9
8.7
40
141
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
14.2
8.7
14
10
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
50.5
8.7
10
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
4.6
8.6
20
44
A07AA02
ATC
nystatin; oral
2.4
8.6
60
262
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
11.7
8.6
15
13
A41.8
ICD-10 Finland
Other specified sepsis
3.6
8.6
28
80
C03DA01
ATC
spironolactone; oral
1.9
8.6
125
721
C09CA06
ATC
candesartan; oral
1.7
8.5
197
1297
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
27.8
8.5
11
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
8.5
47
184
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
90.9
8.4
9
*
P01BA02
ATC
hydroxychloroquine; oral
2.2
8.4
76
370
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
8.4
54
227
V03AE03
ATC
lanthanum carbonate; oral
12.9
8.4
14
11
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
12.9
8.4
14
11
WX202
NOMESCO Finland
Supraclavicular plexus blockade
4.9
8.4
18
37
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
8.4
101
547
I50.0
ICD-10 Finland
Congestive heart failure
2.1
8.4
82
412
2830X
ICD-9 Finland
Acquired haemolytic anaemias, Autoimmune haemolytic anaemias[ANAEMIA HAEMOLYTICA AUTOIMMUNISATORIA NUD]
+∞
8.3
8
*
AA1AD
NOMESCO Finland
CT of head and brain
1.6
8.3
248
1736
R31
ICD-10 Finland
Unspecified haematuria
1.9
8.3
111
622
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
8.3
36
123
104
Kela drug reimbursment
Thyroid insufficiency
2.2
8.3
68
318
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.3
333
2494
A02BC01
ATC
omeprazole; systemic
1.6
8.2
249
1748
XG410
NOMESCO Finland
Flow-volume spirometry
2.7
8.1
43
164
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.4
8.1
28
83
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
17.4
8.1
12
7
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
17.4
8.1
12
7
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
8.0
125
735
C01BD01
ATC
amiodarone; systemic
3.2
8.0
32
104
C07AB02
ATC
metoprolol; systemic
1.6
8.0
194
1289
A12AA12
ATC
[U] calcium acetate
22.2
8.0
11
5
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
7.9
219
1505
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
7.9
97
529
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.3
7.9
29
90
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
8.6
7.8
16
19
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
10.9
7.8
14
13
H05BX01
ATC
cinacalcet; oral
9.5
7.8
15
16
1518, ,
Kela drug reimbursment
15.2
7.7
12
8
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.7
128
769
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
7.6
72
357
205
Kela drug reimbursment
Chronic hypertension
1.6
7.6
252
1803
WZC30
NOMESCO Finland
Teaching
1.7
7.6
134
818
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
25.2
7.6
10
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
25.2
7.6
10
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
9.0
7.6
15
17
AC4
HP
MVP
10.1
7.5
14
14
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
4.3
7.5
19
45
J01CA04
ATC
amoxicillin; systemic
1.6
7.5
697
6155
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.7
7.5
39
148
C07AG02
ATC
carvedilol; oral
2.2
7.4
64
306
1AA09, ,
NOMESCO Finland
80.7
7.4
8
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
80.7
7.4
8
*
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
80.7
7.4
8
*
WVA20
NOMESCO Finland
Medicine administration
3.0
7.3
32
110
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.3
215
1495
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
+∞
7.3
7
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
+∞
7.3
7
*
N08.2*D57.8
ICD-10 Finland
Glomerular disorders in sickle-cell disorders
+∞
7.3
7
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.3
167
1093
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
7.3
175
1159
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.9
7.3
21
55
D69.5
ICD-10 Finland
Secondary thrombocytopenia
15.9
7.2
11
7
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
15.9
7.2
11
7
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.0
7.2
32
111
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.1
7.2
67
330
S97
ICPC
Chronic ulcer skin
2.2
7.2
62
297
212
Kela drug reimbursment
Gout
3.5
7.2
24
70
L03AA13
ATC
pegfilgrastim; parenteral
2.4
7.1
46
194
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
12.1
7.1
12
10
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
8.9
7.1
14
16
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
10.1
7.0
13
13
AB2
HP
AVR bio, stent
10.1
7.0
13
13
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
10.1
7.0
13
13
N05CF01
ATC
zopiclone; oral
1.5
7.0
277
2051
RS220, ,
NOMESCO Finland
4.3
7.0
18
43
J01DB01
ATC
cefalexin; oral
1.6
7.0
699
6206
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
6.9
42
172
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
6.9
54
248
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
7.6
6.9
15
20
A10AE04
ATC
insulin glargine; parenteral
1.9
6.9
89
493
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.9
152
985
R80
ICD-10 Finland
Isolated proteinuria
8.3
6.8
14
17
3025
Kela drug reimbursment
Calcium carbonate
9.4
6.8
13
14
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.2
6.8
17
28
RD210, ,
NOMESCO Finland
3.6
6.7
22
63
RS221, ,
NOMESCO Finland
3.9
6.7
19
49
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
6.7
56
265
L01BB05
ATC
fludarabine; systemic
22.7
6.7
9
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
22.7
6.7
9
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
22.7
6.7
9
*
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
3.8
6.7
20
54
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.8
6.7
20
54
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.1
6.6
18
45
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
5.5
6.6
18
33
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.6
287
2162
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.6
145
937
B01AB04
ATC
dalteparin; parenteral
2.3
6.6
50
227
81
HP
Angiography of the heart and coronary arteries
2.0
6.4
69
359
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
70.3
6.4
7
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.5
6.4
14
19
J02AC03
ATC
voriconazole; systemic
14.4
6.4
10
7
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
14.4
6.4
10
7
LEB00
NOMESCO Finland
Biopsy of vagina
3.8
6.4
19
51
WX402
NOMESCO Finland
General anaesthesia
1.6
6.4
163
1094
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
5.2
6.3
18
35
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.6
6.3
17
31
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.5
6.3
21
61
F43.29
ICD-10 Finland
Adaptation disorder UNS
3.4
6.3
22
66
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
11.1
6.3
11
10
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
9.3
6.3
12
13
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
9.3
6.3
12
13
RS222, ,
NOMESCO Finland
3.9
6.3
18
47
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
18.2
6.3
9
5
6112
FHL
Installation of a peritoneal dialysis or lavage catheter in an operating room
+∞
6.3
6
*
D55.9
ICD-10 Finland
Anaemia due to enzyme disorder, unspecified
+∞
6.3
6
*
D58.9
ICD-10 Finland
Hereditary haemolytic anaemia, unspecified
+∞
6.3
6
*
4AA25, ,
NOMESCO Finland
+∞
6.3
6
*
28391
ICD-8 Finland
Acquired haemolytic anaemias, Autoimmunisatoria secundaria
+∞
6.3
6
*
AC1
HP
MVR mechanical
26.9
6.2
8
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
12.6
6.1
10
8
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
12.6
6.1
10
8
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.1
154
1031
J94.8
ICD-10 Finland
Other specified pleural conditions
3.6
6.1
19
53
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.4
6.1
40
171
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
6.1
43
190
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
6.8
6.0
14
21
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
3.5
6.0
20
58
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
5.6
6.0
16
29
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
548
888
14.06
307.65
14.4
2.3
3.21
1.76
%
38.66
523
793
470
329
28.57
307.65
8.0
1.6
0.88
1.48
g/l
17.92
336
287
368
178
34.11
307.65
4.8
1.4
—
—
—
0
0
481
661
14.36
307.65
14.0
2.2
117.97
68.56
e9/l
21.67
392
517
169
59
34.97
259.17
1.4
1.2
—
—
—
0
0
165
115
17.32
188.23
1.5
1.5
—
—
—
0
0
427
1082
6.57
173.27
4.9
2.4
2.16
2.33
g/l
8.26
406
1012
412
1022
6.55
170.67
5.1
2.4
27.59
22.52
%
5.73
363
874
444
1184
6.39
169.95
5.0
2.4
14.59
12.90
umol/l
3.31
422
1110
295
543
7.57
164.68
4.8
2.6
10.04
10.51
g/l
0.52
281
501
262
434
8.08
161.00
2.7
1.6
1.72
1.53
g/l
0.37
241
398
122
79
17.69
143.66
1.4
1.2
—
—
—
0
0
93
33
31.29
140.22
3.8
1.5
135.45
66.77
mg/l
2.09
85
26
177
232
9.24
131.51
3.3
3.6
55.78
1.85
ratio
—
9
23
179
238
9.12
131.46
3.4
3.6
55.44
83.21
mg/l
0.46
148
191
179
239
9.09
131.00
3.4
3.7
26.84
49.60
mg/l
1.05
148
194
280
632
5.96
124.02
3.4
2.7
65.57
66.40
g/l
0.76
266
573
253
526
6.28
122.23
3.4
2.3
—
—
—
0
0
145
166
10.21
119.27
2.0
1.6
—
—
—
0
0
148
176
9.85
118.26
3.4
3.9
—
—
—
0
0
505
1959
4.56
112.87
3.5
2.1
4.04
3.08
mg/l
7.78
460
1675
222
470
5.93
104.05
1.6
1.4
—
—
—
0
0
281
742
5.04
102.04
2.2
1.5
—
—
—
0
0
92
66
15.40
101.97
1.2
1.1
—
—
—
0
0
116
128
10.24
97.55
1.4
1.3
280.96
237.96
u/ml
0.56
70
69
120
139
9.80
97.32
1.7
1.4
—
—
—
0
0
327
1014
4.48
96.17
15.2
5.6
1.13
1.05
mmol/l
3.58
313
930
666
3440
4.52
94.28
14.2
5.4
57.52
57.38
%
0.08
642
3241
661
3398
4.49
94.14
16.9
5.9
—
—
—
0
0
649
3301
4.40
93.64
15.0
5.5
0.65
0.66
%
0.20
626
3087
289
832
4.63
93.35
5.6
2.7
11.53
9.00
umol/l
0.99
269
718
661
3420
4.44
92.72
15.9
5.8
8.84
8.68
%
0.54
640
3208
693
3712
4.67
92.50
14.5
5.5
2.24
1.93
e9/l
0.88
639
3294
103
104
11.04
92.18
11.5
1.7
—
—
—
0
0
683
3629
4.57
91.97
14.4
5.4
0.04
0.04
e9/l
0.40
626
3147
682
3621
4.56
91.90
14.4
5.4
0.59
0.59
e9/l
0.03
626
3136
657
3402
4.38
91.61
15.3
5.5
2.52
2.87
%
3.90
635
3184
666
3504
4.39
90.21
15.5
5.6
27.78
27.54
%
0.15
644
3296
164
296
6.54
90.07
3.4
2.1
3.28
3.65
g/l
2.28
155
267
164
297
6.52
89.75
3.4
2.1
6.03
7.45
g/l
15.76
155
267
158
278
6.67
88.94
3.5
2.1
2.91
3.04
g/l
0.76
149
248
689
3742
4.50
88.46
15.6
5.7
0.17
0.19
e9/l
5.12
638
3298
303
961
4.23
85.15
2.2
1.6
—
—
—
0
0
136
216
7.23
84.28
3.6
1.4
0.19
0.24
g/l
8.26
122
206
131
206
7.26
81.86
1.4
1.3
—
—
—
0
0
136
226
6.90
80.65
3.5
1.4
0.99
1.18
g/l
8.84
129
215
243
679
4.52
80.44
17.4
7.2
13.18
9.87
mmol/l
4.63
237
643
605
3130
3.80
80.31
6.2
2.7
401.52
134.77
ug/l
5.90
578
2861
149
276
6.26
79.32
3.6
2.1
10.06
10.34
g/l
0.23
139
245
88
88
10.97
79.07
10.7
1.6
33.60
32.94
pg
0.68
88
88
102
125
9.07
78.82
1.7
1.4
117.89
109.88
u/ml
0.42
23
24
711
4190
4.22
75.34
21.6
8.6
4.18
4.14
e9/l
0.06
655
3682
673
3846
3.91
74.14
18.2
6.2
18.82
12.30
umol/l
10.67
662
3641
221
609
4.48
74.00
8.2
3.9
0.79
1.17
%
1.62
151
209
204
552
4.48
69.65
7.5
3.8
0.64
0.73
%
0.29
134
176
270
897
3.86
69.43
1.6
1.3
587.22
411.94
titre
0.99
72
191
308
1141
3.57
66.88
2.2
1.8
—
—
—
0
0
315
1188
3.53
66.45
4.4
2.0
30.49
29.90
s
0.60
309
1145
643
3751
3.45
64.45
18.4
6.9
1.20
1.21
mmol/l
2.26
569
3197
607
3429
3.33
64.09
16.1
6.2
1.21
1.21
mmol/l
1.03
575
3118
408
1840
3.21
63.59
2.2
1.6
22.96
20.27
nmol/l
0.94
375
1542
581
3213
3.25
63.35
10.7
4.8
34.45
35.31
g/l
2.95
555
3004
123
241
5.75
61.21
3.8
2.1
38.03
37.53
g/l
0.35
114
211
305
1191
3.35
59.98
6.1
3.5
0.82
0.82
mmol/l
0.33
292
1115
196
572
4.10
59.86
8.6
4.0
0.07
0.15
%
0.94
125
173
86
121
7.75
58.95
1.4
1.2
64.84
37.66
u/l
1.09
76
105
331
1377
3.21
58.30
2.1
1.4
2.04
2.47
g/l
3.84
252
813
401
1877
3.04
57.22
5.4
2.6
374.21
6895.58
umol/l
7.23
370
1625
337
1479
3.03
53.26
2.1
1.7
1416.28
1177.35
nmol/l
2.98
281
1110
181
542
3.92
52.90
8.4
4.1
0.07
0.78
%
0.61
107
144
453
2349
2.85
52.29
7.2
2.4
—
—
—
0
0
187
581
3.79
51.75
8.6
3.8
128.73
87.53
ng/l
3.74
165
509
435
2220
2.84
51.58
12.5
3.8
7.39
7.40
ph
0.63
77
410
534
3042
2.84
51.02
2.9
2.0
94.79
94.63
pmol/l
0.03
343
1540
61
68
9.55
50.36
1.3
1.2
—
—
—
0
0
79
123
6.94
49.28
1.4
1.2
—
—
—
0
0
61
73
8.89
47.67
2.5
2.5
—
—
—
0
0
408
2099
2.72
46.41
7.6
4.1
—
—
—
0
0
369
1816
2.74
45.68
16.0
6.4
—
—
—
0
0
182
608
3.49
44.70
1.7
1.4
—
—
—
0
0
36
23
16.26
41.92
2.3
1.7
—
—
—
0
0
557
3464
2.58
41.15
6.9
2.6
—
—
—
0
0
354
1783
2.62
40.90
6.3
2.4
—
—
—
0
0
359
1840
2.57
39.77
9.7
3.9
85.57
87.44
%
0.59
353
1800
35
25
14.52
38.38
1.3
1.2
—
—
—
0
0
34
24
14.68
37.52
3.4
2.6
—
—
—
0
0
56
83
7.13
36.43
6.8
4.4
—
—
—
0
0
196
776
2.95
35.58
11.3
4.0
0.85
2.11
mmol/l
5.30
168
609
406
2313
2.37
34.49
6.4
3.4
43.71
90.96
e6/l
0.91
343
1805
60
102
6.23
34.24
1.6
1.2
3.89
5.51
u/ml
0.29
27
49
630
4373
2.44
33.33
11.0
4.9
6.91
6.71
mmol/l
1.14
594
4083
445
2672
2.31
33.02
7.3
3.9
69.44
114.82
e6/l
0.72
350
1925
50
73
7.19
32.94
1.9
2.4
—
—
—
0
0
35
33
10.99
32.38
2.0
1.7
—
—
—
0
0
543
3572
2.30
32.00
32.1
16.3
1.51
1.28
inr
3.40
159
1028
505
3237
2.26
31.51
25.9
9.2
0.11
0.00
e9/l
0.57
435
2656
391
2272
2.27
30.81
4.4
3.2
2087.47
1500.96
ng/l
1.56
349
1949
374
2136
2.28
30.70
6.1
3.2
0.51
0.49
e6/l
0.03
313
1650
738
5610
2.69
30.45
19.5
7.4
83.65
80.24
u/l
1.35
720
5251
361
2045
2.27
30.09
6.0
3.2
—
—
—
0
0
167
660
2.88
30.05
17.5
8.5
—
—
—
0
0
77
185
4.46
29.74
1.4
1.2
86.00
68.75
titre
—
10
16
172
695
2.82
29.67
3.6
2.2
0.21
0.21
g/l
0.13
162
647
230
1076
2.52
29.56
2.5
2.0
—
—
—
0
0
33
33
10.34
29.30
3.2
2.3
1678.67
1486.55
u/ml
0.09
33
33
40
52
8.00
29.10
1.2
1.1
86.00
85.45
titre
—
10
11
248
1217
2.43
28.63
5.0
3.1
2.30
2.01
e6/l
0.29
166
691
297
1581
2.31
28.41
5.8
3.0
507.06
548.71
mosm/kgh2o
3.18
264
1356
462
2941
2.16
28.27
3.5
2.3
75.85
77.37
nmol/l
0.64
435
2594
56
107
5.51
28.27
1.1
1.0
—
—
—
0
0
293
1566
2.29
27.64
3.8
1.7
2.94
1.32
mg/l
1.94
247
1223
385
2317
2.15
26.85
6.4
3.3
38.72
32.93
u/l
2.31
374
2200
56
113
5.22
26.61
1.1
1.1
—
—
—
0
0
298
1636
2.22
26.08
4.8
2.6
4.65
4.95
e6/l
0.17
273
1471
34
43
8.18
25.27
1.5
1.7
—
—
—
0
0
250
1295
2.28
25.05
4.6
2.9
1.20
1.03
e6/l
0.38
168
764
35
47
7.71
24.75
2.2
2.5
34.49
39.81
%
0.49
14
27
696
5364
2.28
24.20
6.7
4.1
21.62
12.64
mm/h
18.21
660
4913
138
551
2.77
24.07
7.3
4.3
7.42
7.40
ph
0.50
16
55
139
558
2.76
23.99
7.2
4.3
5.05
5.14
kpa
0.61
134
536
33
16
21.35
22.69
5.9
4.5
—
—
—
0
0
395
2530
1.99
22.11
4.5
3.3
2.31
2.35
mmol/l
6.15
355
2222
50
109
4.80
21.72
2.1
1.6
0.73
0.83
g/l
0.18
40
86
32
18
18.39
20.98
1.2
1.2
—
—
—
0
0
149
662
2.50
20.80
2.4
2.0
349.54
374.60
nmol/l
0.84
139
604
65
183
3.75
20.20
5.6
3.3
0.83
0.85
nmol/l
0.05
19
145
84
281
3.19
19.99
4.8
3.5
0.59
0.28
g/l
1.22
47
121
89
309
3.08
19.89
3.1
1.9
5.33
2.52
ug/l
0.41
81
268
656
5104
2.03
19.84
7.6
4.4
—
—
—
0
0
357
2290
1.92
19.20
4.1
2.5
66.35
60.09
u/l
0.62
347
2127
25
9
28.51
18.80
10.2
7.3
6.21
6.69
mmol/l
—
25
9
31
50
6.38
18.56
1.1
1.1
—
—
—
0
0
174
868
2.24
18.53
2.1
1.7
—
—
—
0
0
170
884
2.14
16.16
11.9
8.0
0.74
1.28
mmol/l
1.09
135
707
25
15
17.11
16.14
1.1
1.0
—
—
—
0
0
245
1456
1.94
16.06
5.7
3.9
250.64
357.55
ng/l
0.58
210
1169
58
178
3.41
15.84
1.3
1.2
2.67
5.92
u/ml
0.45
11
25
169
885
2.12
15.74
12.0
8.0
4.81
5.10
kpa
3.56
162
853
169
886
2.12
15.69
11.9
7.9
11.74
11.97
kpa
0.25
160
854
46
122
3.92
15.55
1.5
1.4
—
—
—
0
0
55
167
3.44
15.27
10.1
3.3
—
—
—
0
0
136
663
2.24
15.14
3.9
2.3
43.14
108.36
u/l
0.43
125
561
50
144
3.62
15.03
7.2
3.3
58.24
59.09
%
0.14
50
144
58
186
3.26
14.77
1.3
1.2
69.75
18.81
u/ml
—
6
8
56
177
3.31
14.60
1.4
1.2
2.55
2.84
u/ml
—
6
19
99
428
2.47
14.47
8.0
4.5
—
—
—
0
0
325
2175
1.77
14.25
4.9
3.2
2465.49
314.94
mg/l
3.28
250
1394
25
21
12.21
14.14
1.2
2.1
—
—
—
0
0
153
803
2.09
14.07
12.6
8.3
95.61
95.58
%
0.02
147
776
131
648
2.19
14.03
2.4
2.6
12.59
7.21
ug/l
0.70
119
572
331
2235
1.76
14.03
2.6
2.1
213.76
264.78
u/l
0.28
317
2092
481
3602
1.71
14.01
5.9
3.9
0.00
0.00
estimate
0.50
109
753
62
215
3.02
13.86
3.5
3.1
—
—
—
0
0
613
4919
1.76
13.79
6.7
4.7
1066.40
3335.42
e6/l
—
10
79
401
2868
1.71
13.75
5.4
3.8
42.06
56.19
ng/l
0.53
322
2092
23
18
13.08
13.45
1.5
1.4
—
—
—
0
0
348
2407
1.72
13.39
4.0
3.3
—
—
—
0
0
47
143
3.41
13.02
1.3
1.2
51.75
29.12
u/ml
—
8
12
31
70
4.55
12.92
1.6
1.4
—
—
—
0
0
480
3643
1.67
12.88
5.9
3.9
0.03
0.00
estimate
0.40
99
678
336
2331
1.70
12.61
5.5
3.2
6.58
7.48
mmol/l
4.17
294
1941
474
3602
1.66
12.52
8.2
5.2
0.00
0.00
estimate
-0.00
103
700
30
68
4.53
12.45
1.6
1.4
2.12
2.82
g/l
0.99
21
51
30
68
4.53
12.45
1.6
1.4
7.31
6.85
g/l
0.10
20
52
30
68
4.53
12.45
1.6
1.4
0.37
0.39
g/l
0.11
20
51
28
60
4.78
12.42
1.3
1.1
—
—
—
0
0
85
368
2.45
12.37
7.3
5.0
24.03
24.85
mmol/l
1.51
80
345
257
1679
1.74
11.87
4.5
3.8
—
—
—
0
0
86
386
2.36
11.55
2.8
2.5
—
—
—
0
0
43
134
3.32
11.49
12.3
2.8
70.00
61.51
%
1.51
43
134
20
18
11.33
11.08
1.4
1.0
—
—
—
0
0
166
971
1.87
11.01
1.4
1.2
—
—
—
0
0
392
2903
1.62
11.01
5.3
3.6
5.71
5.88
ph
0.30
12
186
31
81
3.93
10.73
3.4
2.6
0.52
1.69
g/24h
2.36
17
36
15
7
21.76
10.70
1.1
1.1
—
—
—
0
0
88
418
2.22
10.35
14.7
11.1
—
—
—
0
0
323
2309
1.62
10.32
6.0
3.8
22.01
9.47
mg/mmol
2.77
239
1448
219
1420
1.71
10.19
3.6
3.0
2.44
2.46
mmol/l
1.08
193
1254
20
22
9.27
10.05
1.3
1.3
—
—
—
0
0
27
67
4.12
10.02
1.1
1.1
—
—
—
0
0
95
472
2.13
9.98
3.0
2.9
4.64
7.20
e9/l
0.96
78
375
123
673
1.96
9.93
3.9
3.0
373.41
208.41
ng/l
2.46
115
620
19
21
9.22
9.55
1.0
1.0
—
—
—
0
0
35
108
3.33
9.52
1.1
1.1
—
13.13
—
0
7
39
129
3.11
9.49
7.1
2.6
—
—
—
0
0
25
62
4.12
9.29
1.5
1.3
—
—
—
0
0
555
4569
1.55
9.19
5.5
3.1
56.62
49.33
u/l
1.24
523
4242
29
81
3.67
9.17
1.7
1.3
42140.63
121994.89
e6/l
0.45
19
45
43
154
2.88
9.13
5.9
3.7
—
—
—
0
0
18
20
9.16
9.05
1.1
1.1
—
—
—
0
0
15
12
12.69
8.88
1.3
1.5
—
—
—
0
0
798
7222
1.87
8.70
40.5
14.8
20.74
24.83
mg/l
4.81
721
5747
40
142
2.90
8.63
4.1
2.4
15.27
15.96
%
0.42
25
75
77
379
2.13
8.29
1.2
1.2
—
—
—
0
0
30
92
3.34
8.26
1.7
1.3
784.86
1607.57
e6/l
1.23
21
63
277
1993
1.56
8.25
1.6
1.4
—
—
—
0
0
43
163
2.72
8.24
1.2
1.3
404.73
242.31
miu/ml
0.85
11
77
18
38
4.81
8.14
1.0
1.0
—
—
—
0
0
367
2816
1.51
8.08
2.7
2.1
—
—
—
0
0
37
131
2.90
8.04
1.5
1.3
—
—
—
0
0
38
137
2.85
7.99
8.2
2.6
—
—
—
0
0
234
1632
1.58
7.93
2.0
1.7
468.65
12840315.87
pmol/l
1.04
192
1324
139
860
1.73
7.50
1.7
1.4
—
—
—
0
0
30
99
3.10
7.37
2.8
2.7
—
—
—
0
0
24
69
3.55
7.30
1.1
1.1
—
—
—
0
0
7
0
+∞
7.30
4.4
0.0
—
—
—
0
0
15
21
7.24
6.72
6.3
4.6
46.03
49.24
%
0.15
15
21
27
89
3.10
6.66
1.2
1.1
—
—
—
0
0
102
606
1.77
6.32
10.6
3.4
1.22
1.23
mmol/l
0.94
95
517
94
545
1.81
6.32
8.3
5.4
—
—
—
0
0
89
510
1.83
6.22
11.2
7.6
23.81
24.53
mmol/l
0.90
84
489
21
62
3.44
6.17
6.8
2.9
9.87
10.60
%
0.50
21
62
99
588
1.77
6.15
1.6
1.6
—
—
—
0
0
32
122
2.68
6.12
1.8
3.0
—
—
—
0
0
124
788
1.66
6.03
3.7
4.3
8.52
26.96
ug/l
0.91
108
663
60
306
2.03
5.93
2.9
1.9
—
—
—
0
0
24
80
3.05
5.83
1.7
1.4
—
—
—
0
0
620
5457
1.43
5.77
4.3
3.9
14.93
14.89
pmol/l
0.11
566
4887
25
86
2.96
5.77
2.8
1.8
88.89
89.88
%
0.48
25
86
15
27
5.63
5.70
1.2
1.0
—
—
—
0
0
17
46
3.75
5.66
3.2
2.3
508.71
493.00
min
0.35
17
27
126
817
1.63
5.66
3.0
2.2
178.07
127.52
ug/g
1.04
101
655
112
705
1.67
5.64
6.5
4.1
—
—
—
0
0
168
1167
1.54
5.63
1.3
1.3
47.30
34.56
iu/ml
0.54
56
375
66
356
1.92
5.57
10.0
6.2
2.31
1.56
%
4.68
61
340
36
154
2.39
5.47
7.6
4.4
2.74
2.70
mmol/l
0.03
23
103
799
7427
1.64
5.46
44.5
17.6
139.09
139.62
mmol/l
7.15
788
7209
65
352
1.91
5.43
10.1
6.2
0.98
0.90
%
0.64
60
336
40
180
2.28
5.43
3.8
2.5
—
—
—
0
0
11
14
7.94
5.35
1.7
1.6
—
—
—
0
0
16
34
4.77
5.32
1.0
1.0
—
—
—
0
0
13
22
5.98
5.23
1.8
1.2
—
—
—
0
0
799
7443
1.62
5.22
46.4
17.7
4.04
3.98
mmol/l
5.66
784
7212
41
190
2.21
5.20
1.3
1.2
—
—
—
0
0
209
1543
1.46
5.18
1.3
1.3
2.52
2.04
u/ml
0.11
43
407
24
87
2.81
5.07
1.4
1.8
70.93
64.90
%
0.43
18
61
24
87
2.81
5.07
1.2
1.1
1.66
1.55
g/l
0.77
24
79
24
87
2.81
5.07
1.6
1.6
—
—
—
0
0
10
12
8.41
5.07
1.3
1.5
—
—
—
0
0
12
20
6.06
4.92
3.9
1.4
—
—
—
0
0
157
1108
1.50
4.85
1.3
1.3
57.40
13.42
u/ml
0.42
39
403
22
78
2.87
4.84
5.4
2.9
—
—
—
0
0
9
10
9.08
4.79
2.3
2.8
—
—
—
0
0
17
53
3.25
4.63
4.9
2.8
—
—
—
0
0
15
43
3.53
4.63
2.5
1.3
0.91
0.97
g/l
0.37
15
43
19
65
2.96
4.46
3.4
3.5
186.82
20.10
mg/l
1.35
14
49
717
6586
1.42
4.45
5.5
4.7
2.08
2.12
mu/l
0.06
667
5940
30
131
2.33
4.40
1.4
1.7
—
—
—
0
0
21
77
2.77
4.37
1.7
1.3
—
—
—
0
0
48
254
1.94
4.34
11.4
8.0
1.16
1.23
mmol/l
0.30
38
228
34
158
2.20
4.32
3.5
2.1
117.19
128.31
g/l
1.36
27
117
274
2187
1.36
4.24
5.6
4.0
—
—
—
0
0
66
390
1.75
4.22
7.0
4.1
—
—
—
0
0
11
21
5.29
4.15
1.7
1.1
—
—
—
0
0
8
10
8.06
4.06
1.8
1.4
—
—
—
0
0
43
225
1.96
4.03
1.3
1.5
260.76
283.83
ug/g
0.36
34
133
9
14
6.48
3.99
2.1
1.3
—
—
—
0
0
9
14
6.48
3.99
1.6
1.6
—
—
—
0
0
93
613
1.58
3.92
3.5
3.5
—
—
—
0
0
31
145
2.18
3.90
3.1
1.4
1.19
0.85
nmol/l
1.77
25
121
113
781
1.51
3.85
1.5
1.3
—
—
—
0
0
17
60
2.87
3.81
1.2
1.1
—
—
—
0
0
42
223
1.93
3.79
1.6
1.6
—
—
—
0
0
570
5107
1.31
3.76
5.4
4.0
—
—
—
0
0
248
1986
1.34
3.68
6.6
4.1
0.02
0.01
estimate
0.32
94
678
126
900
1.46
3.66
1.4
1.3
—
—
—
0
0
803
7599
1.49
3.66
25.3
10.4
25.62
25.61
u/l
0.01
790
7295
38
198
1.96
3.63
3.4
2.3
107.54
102.52
ug/min
0.04
28
115
28
133
2.14
3.42
1.6
1.3
57.68
64.61
mmol/l
0.48
22
114
7
10
7.04
3.37
2.9
3.1
—
—
—
0
0
7
10
7.04
3.37
1.6
1.6
—
—
—
0
0
18
72
2.53
3.22
1.3
1.1
—
—
—
0
0
14
49
2.89
3.20
1.1
1.1
—
—
—
0
0
6
8
7.54
3.06
1.7
2.3
—
—
—
0
0
67
436
1.58
3.02
1.2
1.2
158.30
226.87
u/ml
0.40
53
395
28
524
0.52
3.02
1.1
1.4
—
—
—
0
0
19
81
2.37
3.00
1.6
1.5
—
—
—
0
0
9
21
4.32
3.00
2.1
1.4
—
—
—
0
0
51
315
1.66
2.85
1.2
1.2
—
—
—
0
0
201
1618
1.31
2.82
5.8
4.2
1.02
1.02
kg/l
0.30
26
232
239
1979
1.28
2.69
6.8
3.5
—
—
—
0
0
19
86
2.24
2.65
1.1
1.2
—
—
—
0
0
13
49
2.68
2.63
3.2
2.0
—
—
—
0
0
24
120
2.03
2.63
1.5
1.4
—
—
—
0
0
7
15
4.69
2.60
1.3
1.2
—
—
—
0
0
5
7
7.18
2.55
1.8
2.3
1.43
1.26
umol/l
—
5
7
7
16
4.40
2.48
2.3
1.9
—
—
—
0
0
783
7477
1.35
2.45
38.5
14.2
—
—
—
0
0
10
33
3.05
2.36
1.3
1.5
—
—
—
0
0
197
2368
0.79
2.35
3.8
2.9
—
—
—
0
0
38
230
1.68
2.33
1.2
1.2
—
—
—
0
0
9
29
3.12
2.23
1.0
1.1
154.42
190.02
iu/ml
—
9
29
5
9
5.58
2.21
3.0
2.4
—
—
—
0
0
9
30
3.02
2.15
2.2
3.3
—
—
—
0
0
48
317
1.54
2.10
3.3
2.7
—
—
—
0
0
16
75
2.15
2.09
1.3
1.2
—
—
—
0
0
16
76
2.13
2.03
2.6
2.1
—
—
—
0
0
13
57
2.30
1.98
1.2
1.5
35.66
26.15
%
—
8
40
66
475
1.42
1.92
4.2
3.2
—
—
—
0
0
57
399
1.46
1.92
3.2
3.3
4.11
4.58
pmol/l
2.35
47
349
13
58
2.26
1.91
1.4
1.4
—
—
—
0
0
14
65
2.17
1.88
2.4
2.8
8.55
6.93
mmol/l
—
8
44
12
249
0.47
1.84
1.0
1.1
—
—
—
0
0
16
81
1.99
1.75
1.1
1.2
—
—
—
0
0
11
48
2.31
1.71
1.3
1.5
92.55
79.10
umol/l
1.25
11
48
7
25
2.81
1.65
2.4
2.0
—
—
—
0
0
83
638
1.33
1.65
8.6
3.7
—
—
—
0
0
6
20
3.01
1.58
1.2
1.0
1084.67
1575.00
miu/ml
—
6
20
122
1481
0.80
1.56
2.9
3.1
0.90
0.78
ug/l
0.44
95
997
7
27
2.60
1.51
2.4
2.7
—
—
—
0
0
6
136
0.44
1.41
1.8
1.7
—
—
—
0
0
43
305
1.43
1.41
8.4
4.6
—
—
—
0
0
10
46
2.19
1.40
1.0
1.3
1.04
1.08
promille
—
5
37
29
190
1.54
1.39
1.6
1.7
27400.13
16057.84
e6/l
0.50
23
139
5
18
2.79
1.28
1.4
1.1
—
—
—
0
0
10
49
2.05
1.22
1.1
1.0
310.80
289.91
mg/l
—
10
43
19
116
1.65
1.22
1.9
2.7
—
—
—
0
0
24
157
1.54
1.18
1.3
1.3
4.73
5.30
e6/l
0.08
15
131
24
157
1.54
1.18
1.4
1.3
1225.59
124.70
e6/l
0.60
17
134
12
65
1.86
1.13
5.1
2.1
0.33
2.16
u/field
—
6
25
8
40
2.01
1.12
1.0
1.3
122.50
146.10
nmol/l
—
8
40
20
127
1.59
1.12
1.3
1.6
—
—
—
0
0
69
550
1.28
1.11
1.1
1.2
—
—
—
0
0
5
21
2.39
1.09
1.4
1.0
—
—
—
0
0
7
33
2.13
1.05
3.9
6.9
—
—
—
0
0
7
33
2.13
1.05
11.9
17.8
—
—
—
0
0
7
33
2.13
1.05
1.1
1.3
1.71
1.56
g/l
—
7
33
31
225
1.39
0.95
8.2
5.2
—
—
—
0
0
20
133
1.52
0.95
1.4
1.3
—
—
—
0
0
814
7984
1.19
0.85
63.4
21.9
119.28
134.37
g/l
89.19
809
7842
813
7976
1.19
0.83
63.2
21.8
226.25
246.51
e9/l
10.57
799
7757
813
7978
1.18
0.82
62.8
21.7
93.86
91.06
fl
27.30
807
7843
6
32
1.88
0.82
1.5
1.4
179.83
172.93
mmol/24h
—
6
32
813
7979
1.18
0.81
62.8
21.7
31.09
30.31
pg
15.55
807
7842
813
7979
1.18
0.81
63.1
21.8
7.74
6.81
e9/l
1.95
797
7732
813
7980
1.18
0.80
63.0
21.8
3.90
4.46
e12/l
84.03
797
7736
6
33
1.82
0.79
1.0
1.1
—
21.33
—
0
6
25
182
1.38
0.78
1.2
1.5
11.36
9.99
u/l
0.25
20
146
12
74
1.63
0.78
2.3
2.6
—
—
—
0
0
677
6571
1.12
0.77
7.4
6.0
38.05
40.15
mmol/mol
5.00
615
6036
207
1890
1.12
0.76
1.8
1.7
1.43
1.34
mmol/l
0.74
176
1580
62
515
1.22
0.75
1.3
1.4
—
—
—
0
0
812
7978
1.17
0.74
63.8
21.9
35.77
39.84
%
55.39
764
7410
10
160
0.62
0.74
1.2
1.2
—
—
—
0
0
12
77
1.57
0.68
2.8
1.6
—
—
—
0
0
11
69
1.60
0.68
1.6
1.4
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
7
43
1.63
0.67
1.3
1.3
—
—
—
0
0
20
271
0.73
0.66
1.9
1.7
—
—
—
0
0
17
234
0.72
0.63
4.1
1.6
—
—
—
0
0
15
105
1.44
0.60
1.3
1.1
—
—
—
0
0
16
114
1.41
0.59
1.6
1.4
—
—
—
0
0
16
114
1.41
0.59
1.7
1.4
—
—
—
0
0
51
603
0.84
0.58
1.5
1.5
—
—
—
0
0
15
106
1.42
0.58
1.3
1.1
—
—
—
0
0
6
35
1.72
0.57
3.3
3.5
62.00
111.94
nmol/l
—
6
35
16
117
1.37
0.52
1.8
1.5
—
—
—
0
0
14
100
1.41
0.52
1.3
1.1
1.72
1.92
u/ml
—
5
53
704
6900
1.09
0.50
5.1
4.7
6.11
5.97
mmol/l
1.18
635
6211
18
234
0.76
0.48
4.0
1.6
—
—
—
0
0
18
233
0.77
0.47
3.9
1.6
—
—
—
0
0
14
102
1.38
0.47
1.3
1.1
19.43
4.00
u/ml
—
5
59
18
232
0.77
0.46
3.9
1.6
—
—
—
0
0
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
11
77
1.43
0.45
1.8
1.3
—
—
—
0
0
7
50
1.40
0.45
2.6
2.9
—
—
—
0
0
13
174
0.74
0.43
1.1
1.1
—
—
—
0
0
8
57
1.41
0.42
3.1
2.1
20.63
3.44
ug/l
—
8
50
5
33
1.52
0.41
1.4
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
30
355
0.84
0.38
1.1
1.3
—
—
—
0
0
706
6953
1.07
0.35
5.2
4.5
4.31
4.57
mmol/l
8.19
651
6384
6
44
1.37
0.34
3.2
3.2
—
—
—
0
0
6
44
1.37
0.34
1.3
1.3
—
—
—
0
0
11
82
1.35
0.34
1.7
1.2
—
—
—
0
0
71
780
0.90
0.33
1.7
1.6
—
—
—
0
0
676
6654
1.06
0.33
4.9
4.0
1.36
1.26
mmol/l
2.03
612
6018
6
47
1.28
0.32
1.0
1.1
—
8.01
—
0
10
7
52
1.35
0.31
1.1
1.1
65.00
31.64
mg/l
—
7
45
18
218
0.82
0.30
3.8
1.6
—
—
—
0
0
13
102
1.28
0.30
1.1
1.2
—
—
—
0
0
47
522
0.89
0.28
2.3
2.1
10.90
12.63
nmol/l
0.58
36
464
69
636
1.09
0.26
1.7
1.5
—
—
—
0
0
21
242
0.86
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
1.4
1.3
—
—
—
0
0
17
199
0.85
0.22
2.2
2.2
12966.00
4549.62
u/l
—
5
86
0
10
0.00
0.21
0.0
1.0
—
17.44
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
14
166
0.84
0.20
2.6
4.0
20.63
27.92
mg/l
—
8
108
16
184
0.87
0.17
1.7
1.7
54.56
41.61
nmol/l
0.91
16
177
695
6892
1.04
0.16
5.2
4.4
1.40
1.46
mmol/l
2.72
635
6281
15
168
0.89
0.11
2.3
1.7
445.30
5.25
iu/l
—
7
52
258
2541
1.02
0.09
4.4
5.1
2.61
2.68
ug/l
0.07
229
2246
7
65
1.08
0.08
1.1
1.5
—
—
—
0
0
7
67
1.05
0.08
1.0
1.1
—
—
—
0
0
17
158
1.08
0.06
1.5
1.3
—
—
—
0
0
17
179
0.95
0.03
3.9
1.6
—
—
—
0
0
20
209
0.96
0.03
8.3
10.9
—
—
—
0
0
43
438
0.98
0.01
1.3
1.2
—
—
—
0
0
43
438
0.98
0.01
1.3
1.2
71.97
150.58
iu/ml
1.36
20
167
16
153
1.05
0.01
8.6
2.0
—
—
—
0
0
710
7091
1.01
0.01
5.7
5.0
2.45
2.68
mmol/l
9.84
648
6473
11
107
1.03
0.00
5.5
1.8
—
—
—
0
0
5
52
0.96
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
59
1.02
-0.00
11.8
2.1
14.50
13.24
%
—
6
59
0
7
0.00
-0.00
0.0
2.3
—
124.00
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
38.67
—
0
9
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
50
1.00
-0.00
4.4
2.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_ACQHAEMOLYTICANAEMIA and mortality.

Females

Parameter HR [95% CI] p-value
D3_ACQHAEMOLYTICANAEMIA 2.809 [2.38, 3.31] < 0.001
Birth year 0.994 [0.99, 1.0] 0.164

During the follow-up period (1.1.1998 — 31.12.2019), 1010 out of 2437 females with D3_ACQHAEMOLYTICANAEMIA died.

Males

Parameter HR [95% CI] p-value
D3_ACQHAEMOLYTICANAEMIA 2.96 [2.45, 3.58] < 0.001
Birth year 0.993 [0.98, 1.0] 0.112

During the follow-up period (1.1.1998 — 31.12.2019), 846 out of 2047 males with D3_ACQHAEMOLYTICANAEMIA died.

Mortality risk

Mortality risk for people of age

years, who have D3_ACQHAEMOLYTICANAEMIA.

N-year risk Females Males
1 0.258% 0.614%
5 1.926% 3.519%
10 4.031% 8.893%
15 7.254% 17.108%
20 12.953% 28.787%

Relationships between endpoints

Index endpoint: D3_ACQHAEMOLYTICANAEMIA – Acquired haemolytic anaemia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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