No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
77 |
4. Check minimum number of eventsNone |
77 |
5. Include endpoints |
94 |
6. Filter based on genotype QC (FinnGen only) |
94 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E20-E35
- Name in latin
- Morbi thymi
Similar endpoints
↥List of similar endpoints to
Diseases of thymus
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 615 | 375 | 231 |
| Only index persons | 454 | 281 | 173 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 57.22 | 60.39 | 51.51 |
| Only index persons | 49.79 | 52.25 | 45.80 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 94 | 57 | 37 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 47.72 | 49.08 | 45.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 83
- Matched controls
- 830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E32.9
ICD-10 Finland
Disease of thymus, unspecified
+∞
41.1
36
*
E32.0
ICD-10 Finland
Persistent hyperplasia of thymus
+∞
21.8
20
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
7.0
10.6
28
56
25499
ICD-8 Finland
Diseases of thymus gland
+∞
9.6
9
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
87.6
7.5
8
*
2540A
ICD-9 Finland
Diseases of thymus gland, Persistent hyperplasia of thymus
+∞
7.4
7
*
E32.8
ICD-10 Finland
Other diseases of thymus
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
57
329
2.86
5.77
8.9
6.9
mmol/l
1.2
1.2
0.00
47
271
(3023368) Bacteria identified in Blood by Culture
38
180
2.87
5.56
6.0
3.9
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
17
55
3.55
4.63
1.3
3.0
e9/l
67.7
78.3
—
10
41
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
14
41
3.84
4.38
1.4
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
34
170
2.57
4.32
3.4
2.2
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
43
250
2.33
3.85
4.3
5.3
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
54
350
2.28
3.70
5.6
5.1
estimate
0.0
0.0
—
10
70
(3044640) Blood type and Crossmatch panel - Blood
39
221
2.31
3.68
3.8
2.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
54
355
2.22
3.51
4.2
3.6
estimate
0.0
0.0
—
10
70
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
46
284
2.21
3.49
2.1
1.9
pmol/l
102.6
95.2
0.56
25
153
(3009261) Glucose [Presence] in Urine by Test strip
54
359
2.18
3.37
4.2
3.6
estimate
0.0
0.0
—
10
65
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
15
55
3.06
3.34
5.8
3.2
kpa
5.4
4.9
2.57
15
50
(3004789) Transferrin [Mass/volume] in Serum or Plasma
22
102
2.51
3.18
3.5
2.2
g/l
2.4
2.4
0.13
22
88
(3022096) Basophils/100 leukocytes in Blood
52
347
2.12
3.15
5.8
5.9
%
0.7
0.7
0.20
52
325
(3002030) Lymphocytes/100 leukocytes in Blood
54
368
2.10
3.06
6.1
5.9
%
26.4
27.9
0.42
54
344
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
11
35
3.43
3.04
8.5
4.5
mmol/l
24.4
24.8
0.14
11
35
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
44
280
2.07
2.98
5.2
3.6
ng/l
65.3
37.0
0.33
32
171
(3006504) Eosinophils/100 leukocytes in Blood
52
353
2.06
2.94
6.0
5.9
%
2.6
2.8
0.32
52
329
(3001122) Ferritin [Mass/volume] in Serum or Plasma
47
311
2.02
2.82
4.1
2.6
ug/l
123.8
115.7
0.11
47
285
(3019198) Lymphocytes [#/volume] in Blood
55
385
2.03
2.82
6.1
5.6
e9/l
1.8
1.8
0.23
47
349
(3019069) Monocytes/100 leukocytes in Blood
52
357
2.02
2.81
6.5
6.3
%
9.2
8.3
1.26
52
337
(3018418) pH of Serum or Plasma
35
208
2.09
2.81
7.0
3.8
ph
7.4
7.4
—
8
38
(3013115) Eosinophils [#/volume] in Blood
55
386
2.02
2.79
6.2
6.0
e9/l
0.2
0.2
1.11
47
348
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
46
304
2.00
2.75
2.3
2.3
nmol/l
80.0
75.7
0.49
39
264
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
13
50
2.86
2.66
1.5
1.3
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
53
374
1.96
2.58
6.1
5.6
e9/l
0.0
0.0
0.40
45
333
(3001604) Monocytes [#/volume] in Blood
53
374
1.96
2.58
6.0
5.5
e9/l
0.6
0.6
0.30
45
329
(3019060) Gas panel - Arterial blood
12
47
2.78
2.38
4.0
4.6
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
6
13
4.85
2.31
1.2
1.2
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
16
74
2.40
2.30
2.0
1.6
nmol/l
347.1
382.2
0.33
16
68
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
47
328
1.87
2.28
5.9
4.1
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
8
24
3.54
2.23
2.4
1.7
mmol/l
24.6
23.3
—
8
19
(3041096) Erythrocytes [Presence] in Urine by Automated
32
199
1.92
2.19
4.6
3.5
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
14
4.50
2.18
1.2
1.3
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
11
43
2.76
2.18
13.7
7.9
%
0.5
0.7
1.50
11
43
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
11
44
2.70
2.10
13.2
7.8
%
1.0
1.6
1.09
11
44
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
5
10
5.21
2.09
7.2
2.4
nmol/l
2.1
3.1
—
5
10
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
40
272
1.82
2.06
4.7
3.8
—
—
—
0
0
(3022313) Gas panel - Capillary blood
10
39
2.75
1.99
7.0
3.6
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
33
214
1.84
1.97
3.0
3.1
ng/l
999.6
1193.0
0.23
27
171
(3026008) Bacteria identified in Urine by Culture
33
215
1.82
1.93
4.6
3.2
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
37
254
1.75
1.80
7.6
3.4
mmol/l
2.3
2.4
0.23
32
215
(3037467) Urinalysis macro (dipstick) panel - Urine
64
513
1.78
1.79
5.8
4.3
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
19
106
1.99
1.75
2.3
1.8
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
19
107
1.97
1.70
2.8
2.7
e6/l
5.9
2.4
—
9
57
(3021589) Normoblasts [#/volume] in Blood
42
303
1.70
1.70
10.6
9.2
e9/l
0.0
0.0
0.07
32
246
(1616796) Gas panel - Central venous blood
6
19
3.30
1.69
1.7
1.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
50
2.36
1.64
17.6
7.9
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
36
253
1.69
1.58
2.1
3.1
u/l
27.2
30.2
0.73
36
239
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
8
33
2.55
1.58
8.6
4.2
mmol/l
25.0
25.0
—
8
33
(3007853) Bacteria identified in Skin by Aerobe culture
16
87
2.01
1.57
1.8
1.5
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
37
2.58
1.53
4.8
2.3
%
1.8
1.5
—
9
37
(3013650) Neutrophils [#/volume] in Blood by Automated count
55
436
1.63
1.49
11.7
10.0
e9/l
3.9
4.0
0.11
49
387
(3020891) Body temperature
7
28
2.62
1.48
5.7
4.3
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
5
16
3.24
1.45
1.6
1.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
36
258
1.64
1.45
8.2
7.7
inr
1.0
1.3
5.18
11
73
(3025941) Bacteria identified in Stool by Culture
9
40
2.38
1.45
1.4
1.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
28
188
1.70
1.44
5.8
3.9
estimate
0.0
0.0
—
10
70
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
19
114
1.84
1.42
2.2
1.9
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
5
17
3.05
1.37
2.2
3.6
g/l
0.0
0.0
—
5
17
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
17
3.05
1.37
1.0
1.6
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
9
43
2.21
1.34
2.1
2.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
8
34
2.48
1.33
1.5
1.3
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
6
24
2.60
1.32
2.2
1.6
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
24
158
1.70
1.32
3.5
3.4
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
8
35
2.40
1.30
1.7
2.7
%
55.3
52.3
—
8
35
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
34
246
1.60
1.30
4.1
3.0
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
5
18
2.87
1.30
1.2
1.9
g/l
122.4
128.7
—
5
13
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
18
2.87
1.30
1.0
1.7
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
5
18
2.87
1.30
1.4
1.6
—
—
—
0
0
(4035726)
12
63
2.04
1.29
1.3
1.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
36
265
1.58
1.28
4.7
3.7
e6/l
65.4
47.2
0.23
25
182
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
36
2.33
1.28
13.3
7.1
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
5
19
2.72
1.23
5.4
2.6
g/l
2.7
3.5
—
5
19
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
19
2.72
1.23
1.2
1.1
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
8
40
2.09
1.15
5.4
3.7
g/l
133.1
129.1
—
8
40
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
7
32
2.28
1.10
1.3
1.0
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
70
611
1.57
1.08
31.7
16.6
%
13.9
13.8
0.22
70
601
(1761482) Bacteria [#/volume] in Urine by Culture
5
22
2.34
1.04
1.6
5.5
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
5
22
2.34
1.04
1.8
1.2
—
—
—
0
0
(4010399)
9
48
1.97
1.04
1.1
1.5
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
65
561
1.51
1.03
5.5
4.0
mm/h
14.3
11.4
0.87
57
512
(3013512) EKG study
27
195
1.54
1.02
5.4
4.0
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
9
50
1.88
1.00
2.0
2.8
g/l
65.0
66.8
—
9
45
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
9
50
1.88
1.00
3.7
3.7
mmol/l
1.2
1.2
—
9
45
(40768797) Stomach Pathology biopsy report
17
111
1.65
0.96
1.2
1.2
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
78
705
1.63
0.96
21.1
12.8
ml/min/173m2
82.9
83.3
0.05
70
570
(3012516) Albumin [Mass/volume] in Urine
26
191
1.50
0.90
2.6
3.1
mg/l
32.4
374.5
0.54
18
126
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
17
113
1.62
0.90
3.1
2.5
e6/l
0.4
0.8
—
9
63
(3012544) pH of Venous blood
11
65
1.78
0.86
7.8
3.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
73
1.74
0.86
2.4
1.7
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
12
73
1.74
0.86
2.3
1.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
6
33
1.87
0.80
1.0
2.2
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
24
2.14
0.76
2.4
3.0
—
—
—
0
0
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
24
2.14
0.76
2.4
3.0
g/l
3.3
3.4
—
5
19
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
13
85
1.61
0.73
1.3
1.5
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
81
753
1.55
0.70
25.3
13.4
mg/l
28.8
21.0
1.14
72
587
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
58
512
1.35
0.66
3.2
3.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
84
789
1.61
0.66
23.2
11.8
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
10
64
1.63
0.61
3.7
2.7
u/l
25.8
30.6
—
10
55
(3002256) Pathology report gross observation
12
81
1.55
0.60
1.2
1.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
18
134
1.42
0.58
2.5
1.8
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
26
207
1.35
0.58
3.8
3.7
mg/mmol
2.8
8.2
1.28
18
135
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
36
1.71
0.58
1.5
3.6
mmol/l
25.4
24.3
—
6
36
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
6
38
1.62
0.55
1.3
1.6
ug/l
7.5
8.8
—
6
32
(3019832) Treponema pallidum Ab [Presence] in Serum
9
63
1.47
0.54
1.9
1.6
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
9
63
1.47
0.54
1.1
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
13
92
1.48
0.54
1.3
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
6
40
1.53
0.52
1.8
2.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
27
221
1.31
0.50
4.7
3.1
e6/l
19.5
33.9
0.72
22
167
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
7
46
1.56
0.49
1.9
2.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
15
112
1.40
0.48
2.3
1.5
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
48
1.49
0.48
2.1
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
15
113
1.39
0.46
1.3
1.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
23
187
1.30
0.44
10.8
7.4
—
—
—
0
0
(3003338) MCHC [Mass/volume]
61
657
0.80
0.43
35.0
16.6
g/l
332.7
332.4
0.11
61
652
(3026493) Urate [Moles/volume] in Serum or Plasma
23
189
1.29
0.41
1.9
3.0
umol/l
332.8
1750.0
0.50
16
157
(4094501)
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
34
1.50
0.41
1.8
2.5
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
24
199
1.28
0.40
4.9
2.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
12
89
1.40
0.40
2.0
1.6
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
9
66
1.40
0.40
4.0
3.4
—
—
—
0
0
(3019225) pH of Specimen
9
66
1.40
0.40
3.0
4.6
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
20
163
1.29
0.38
1.3
1.3
u/ml
7.7
0.7
—
7
43
(3020564) Creatinine [Moles/volume] in Serum or Plasma
83
795
1.38
0.38
26.1
15.2
umol/l
81.3
76.2
0.35
83
795
(3000492) Spirometry study
9
71
1.30
0.37
1.2
1.4
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
83
797
1.35
0.35
15.1
10.1
u/l
22.8
26.3
2.37
83
780
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
6
46
1.32
0.33
1.3
2.6
ug/l
3.1
5.3
—
6
40
(3005322) IgE [Units/volume] in Serum or Plasma
7
51
1.40
0.32
1.0
1.2
u/ml
20.5
189.4
—
7
42
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
12
93
1.33
0.32
3.0
2.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
22
189
1.21
0.27
2.0
1.4
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
23
200
1.20
0.25
4.8
2.9
e6/l
0.1
0.4
1.59
18
149
(40768804) Tissue Pathology biopsy report
33
298
1.17
0.24
1.8
1.9
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
5
37
1.37
0.24
1.6
1.6
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
38
1.33
0.23
1.6
1.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
5
38
1.33
0.23
1.6
1.6
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
5
38
1.33
0.23
1.4
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
18
154
1.21
0.23
1.6
1.3
g/l
1.8
2.7
1.69
11
90
(3014051) Protein [Presence] in Urine by Test strip
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
12
0.00
0.21
0.0
1.2
—
32.6
—
0
12
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
13
0.00
0.21
0.0
3.6
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
6
48
1.27
0.20
2.5
1.8
ng/l
248.8
130.8
—
6
41
(1761868) Lipid panel - Serum or Plasma
26
288
0.87
0.20
2.8
2.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
10
81
1.26
0.19
2.9
2.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
10
81
1.26
0.19
1.0
1.3
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
7
60
1.18
0.18
14.3
4.0
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
17
153
1.14
0.12
3.4
4.1
%
17.6
20.0
—
6
64
(40761535) Cells panel - Urine sediment
6
54
1.12
0.09
3.2
3.7
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
71
725
0.92
0.08
3.9
3.9
mmol/l
1.3
1.3
0.07
65
675
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
7
81
0.85
0.07
1.4
1.8
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
81
0.85
0.07
5.7
6.1
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
12
109
1.12
0.06
2.4
2.9
ug/l
0.4
0.7
—
6
70
(3009542) Hematocrit [Volume Fraction] of Blood
69
701
0.94
0.05
30.7
13.8
%
38.5
40.4
1.05
50
540
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
150
1.08
0.04
1.7
1.5
—
—
—
0
0
(3044889) 12 lead EKG panel
52
509
1.05
0.04
4.5
3.6
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
84
837
1.03
0.00
36.8
19.6
e9/l
6.8
6.5
0.63
84
819
(3024731) MCV [Entitic volume]
84
837
1.03
0.00
36.6
19.5
fl
91.7
91.0
0.62
84
829
(3026361) Erythrocytes [#/volume] in Blood
84
837
1.03
0.00
36.7
19.5
e12/l
4.3
4.5
2.46
84
819
(3000963) Hemoglobin [Mass/volume] in Blood
84
837
1.03
0.00
37.0
19.6
g/l
129.6
136.2
2.92
84
828
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
13
133
0.97
0.00
1.1
1.3
iu/ml
28.6
38.4
—
5
46
(40760892) CBC W Ordered Manual Differential panel - Blood
18
177
1.02
0.00
7.6
5.0
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
74
745
0.97
0.00
4.2
4.4
mmol/l
4.5
4.7
0.85
69
697
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
76
756
1.03
0.00
4.6
4.7
mmol/l
2.7
2.8
0.30
70
699
(3007461) Platelets [#/volume] in Blood
84
836
1.04
0.00
36.7
19.6
e9/l
253.9
252.6
0.06
84
822
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
74
739
1.01
0.00
4.0
4.3
mmol/l
1.4
1.5
0.25
69
687
(3035941) MCH [Entitic mass]
84
836
1.04
0.00
36.6
19.4
pg
30.5
30.3
0.41
84
828
(3036071) Salmonella sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4281824)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
3.8
—
180.6
—
0
6
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
1235.0
—
0
5
(3015183) Erythrocyte sedimentation rate
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
12.7
—
0.8
—
0
6
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.4
—
26.6
—
0
5
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
12.1
—
0
5
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
63
0.95
0.00
1.2
1.1
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
6
0.00
0.00
0.0
18.5
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
12.9
—
1709.3
—
0
9
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
0.9
—
0
8
(3000012) Reticulocyte production index
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
5
0.00
0.00
0.0
1.2
—
206.8
—
0
5
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4146454)
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(4211845)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
11.4
—
941.1
—
0
9
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
87.8
—
0
5
(3045142) Bone marrow Pathology biopsy report
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(4062490)
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYMUSDIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYMUSDIS | 2.212 [1.49, 3.28] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 234 females with E4_THYMUSDIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYMUSDIS | 3.602 [1.75, 7.41] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 149 males with E4_THYMUSDIS died.
Mortality risk
Mortality risk for people of age
years, who have E4_THYMUSDIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.18% | 0.795% |
| 5 | 1.148% | 4.018% |
| 10 | 2.685% | 9.576% |
| 15 | 5.111% | 17.15% |
| 20 | 9.273% | 29.089% |
Relationships between endpoints
↥Index endpoint: E4_THYMUSDIS – Diseases of thymus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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