This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Abnormal reflex
R18_ABNORMAL_REFLEX
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
188 |
4. Check minimum number of eventsNone |
188 |
5. Include endpointsNone |
188 |
6. Filter based on genotype QC (FinnGen only) |
184 |
Control definitions (FinnGen only)
- Control exclude
- CD2_BENIGN_FEMALE_GEN_OTH
Extra metadata
- Level in the ICD hierarchy
- 4
- Special
- INCREASEDREFLEXES
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R29
- Name in latin
- Reflexus abnormis
Similar endpoints
↥List of similar endpoints to
Abnormal reflex
based on the number of shared cases.
Similar with more cases:
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 184 | 110 | 74 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 50.27 | 45.63 | 57.18 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 188
- Matched controls
- 1880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R29.2
ICD-10 Finland
Abnormal reflex
+∞
268.8
187
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
11.5
50.1
63
79
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
8.6
26.0
37
52
TAB00
NOMESCO Finland
Lumbar puncture
7.6
17.1
26
39
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
15.6
13.1
21
15
R20.2
ICD-10 Finland
Paraesthesia of skin
4.6
11.4
30
75
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.8
9.9
33
99
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.9
9.5
31
91
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
10.3
9.0
17
18
N03AX12
ATC
[U] gabapentin; oral
3.0
9.0
48
193
AA1AD
NOMESCO Finland
CT of head and brain
2.7
8.4
61
287
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
8.4
51
219
Z01.9
ICD-10 Finland
Special examination, unspecified
4.6
8.2
20
47
SPAT1229
SPAT
Assessment of need for aid
4.5
8.0
20
48
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.4
7.8
31
104
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
6.9
46
206
L12
ICPC
Hand/finger symptom/complaint
2.7
6.8
42
181
SPAT1260
SPAT
Consultation of another employee
2.7
6.7
43
188
R51.80
ICD-10 Finland
Headache
2.7
6.7
43
188
A02BC02
ATC
pantoprazole; systemic
2.4
6.7
136
983
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.6
6.5
22
66
R49.01
ICD-10 Finland
Functional dysphonia
6.4
6.5
16
27
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
6.1
27
96
N06AX21
ATC
duloxetine; oral
2.9
6.1
31
120
R42
ICD-10 Finland
Dizziness and giddiness
2.4
6.1
48
232
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
6.0
50
247
N03AX16
ATC
[U] pregabalin
2.4
6.0
53
269
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
39
5.94
11.15
6.9
2.7
5.05
5.01
kpa
0.08
21
39
36
106
3.96
11.08
4.2
3.9
1.21
1.23
mmol/l
1.05
29
95
43
148
3.47
10.51
5.0
3.4
—
—
—
0
0
32
94
3.90
9.84
5.9
5.5
25.65
25.22
mmol/l
0.28
32
94
62
298
2.61
8.19
1.7
1.7
129167113.98
463.22
pmol/l
0.49
48
253
19
30
6.92
7.95
2.8
2.4
16.58
15.84
%
—
5
11
123
836
2.36
7.22
4.9
4.4
6.49
6.55
mmol/l
0.14
115
773
64
343
2.31
6.47
2.0
1.7
0.67
1.26
mg/l
1.98
47
274
36
147
2.79
6.42
2.3
2.1
349.00
374.86
nmol/l
0.35
31
138
49
234
2.48
6.40
2.0
1.6
1615.15
1225.71
nmol/l
1.55
33
178
114
776
2.19
6.32
5.7
5.7
9.99
10.84
umol/l
0.73
108
740
102
666
2.16
6.28
6.7
6.5
1.21
1.22
mmol/l
0.53
74
560
83
509
2.13
5.92
3.5
2.9
—
—
—
0
0
16
33
5.20
5.58
1.3
1.2
1.50
2.14
e6/l
—
10
28
97
644
2.05
5.47
18.8
12.3
1.18
1.20
inr
0.08
41
207
90
587
2.02
5.28
4.9
3.6
—
—
—
0
0
104
726
1.97
4.92
4.7
3.5
0.00
0.01
estimate
0.50
39
151
67
405
2.02
4.77
3.5
2.5
0.61
0.38
e6/l
0.32
54
300
10
14
7.47
4.71
1.1
1.1
—
—
—
0
0
87
581
1.93
4.60
2.2
2.4
75.31
74.37
nmol/l
0.12
78
530
68
418
1.98
4.59
5.2
3.8
0.00
0.01
estimate
0.50
37
144
90
613
1.90
4.45
7.1
5.5
1.20
1.22
mmol/l
1.14
81
570
103
733
1.90
4.44
5.8
4.6
0.00
0.01
estimate
0.50
38
143
104
743
1.89
4.43
4.7
3.5
0.00
0.00
estimate
-0.00
38
138
166
1404
2.56
4.34
5.7
4.5
1.59
2.74
mu/l
0.76
158
1295
10
17
6.15
4.19
1.1
1.2
—
—
—
0
0
56
334
1.96
4.05
2.2
2.0
2.70
2.89
mg/l
0.39
46
293
143
1163
1.96
3.79
5.2
3.8
15.33
14.60
pmol/l
3.01
134
1074
140
1154
1.83
3.26
4.9
3.7
10.90
10.11
mm/h
0.28
133
1077
69
467
1.75
3.25
3.2
2.4
47.00
54.57
u/l
1.91
62
439
76
532
1.72
3.17
5.4
3.8
43.28
43.57
ng/l
0.00
58
343
39
225
1.93
3.05
3.1
3.0
0.82
0.82
mmol/l
0.04
31
214
56
365
1.76
2.97
1.3
1.3
0.71
1.60
u/ml
1.26
19
109
19
83
2.43
2.95
1.3
1.3
—
—
—
0
0
140
1169
1.77
2.94
8.1
6.8
75.65
78.48
u/l
0.42
133
1095
32
176
1.99
2.87
6.5
5.4
1.09
1.03
mmol/l
1.15
27
165
8
18
4.59
2.83
1.1
1.2
—
—
—
0
0
14
54
2.72
2.77
1.5
1.3
—
—
—
0
0
5
6
8.52
2.76
1.6
1.2
—
—
%
—
0
0
6
10
6.15
2.72
1.2
1.0
—
—
—
0
0
10
30
3.46
2.64
2.5
3.4
3.57
4.65
e9/l
—
10
30
5
7
7.30
2.56
6.8
2.7
17.80
9.43
%
—
5
7
5
7
7.30
2.56
7.0
2.9
—
—
—
0
0
10
31
3.35
2.56
2.5
3.5
56.50
58.13
%
—
10
31
172
1555
2.25
2.55
18.8
12.2
22.55
21.52
mg/l
0.14
143
1232
110
889
1.57
2.37
7.3
9.2
3.79
4.11
e9/l
1.03
97
778
72
529
1.59
2.35
2.1
1.9
88.00
96.44
pmol/l
1.04
44
279
10
34
3.05
2.32
2.6
2.0
25.71
24.02
mmol/l
—
10
34
15
66
2.38
2.31
1.3
1.7
—
—
—
0
0
6
13
4.73
2.29
1.0
1.1
—
—
—
0
0
27
153
1.89
2.23
1.6
1.7
—
—
—
0
0
27
153
1.89
2.23
1.6
1.7
—
—
—
0
0
128
1087
1.56
2.09
4.2
2.9
46.88
45.38
u/l
0.09
116
1034
6
15
4.09
2.05
1.0
1.1
—
—
—
0
0
11
44
2.59
2.05
1.9
1.3
—
—
—
0
0
34
213
1.73
2.04
1.7
1.8
—
—
—
0
0
33
205
1.74
2.04
2.5
2.6
4.45
2.35
e6/l
0.42
16
104
13
57
2.38
2.02
4.2
2.7
0.55
0.74
%
1.68
13
57
80
618
1.51
2.02
5.9
4.1
36.47
36.13
g/l
0.23
73
589
8
27
3.05
1.96
1.6
1.3
—
—
—
0
0
6
16
3.84
1.95
3.5
3.6
102.33
107.81
mmol/l
—
6
16
34
217
1.69
1.91
2.0
1.9
1.46
1.48
%
0.04
28
191
53
382
1.54
1.82
2.7
3.1
1262.73
816.51
ng/l
0.34
44
305
66
500
1.49
1.80
2.6
3.3
2.33
2.35
mmol/l
1.15
61
449
9
36
2.57
1.76
1.3
4.2
—
1.58
—
0
5
19
104
1.92
1.75
1.8
1.5
—
—
—
0
0
160
1456
1.66
1.70
4.5
4.3
5.75
5.84
mmol/l
0.64
150
1348
84
675
1.44
1.67
3.9
2.7
93.29
100.28
ug/l
0.18
76
631
11
49
2.32
1.67
1.4
1.4
0.22
0.23
g/l
0.19
11
49
176
1650
2.04
1.62
11.6
9.4
26.41
25.94
u/l
0.16
169
1602
7
27
2.65
1.53
1.1
1.1
—
—
—
0
0
10
46
2.24
1.42
1.4
1.1
—
—
—
0
0
40
286
1.51
1.42
1.4
1.3
22.28
26.44
iu/ml
0.20
16
102
12
61
2.03
1.36
2.7
2.1
54.74
4950.42
u/l
—
5
19
48
362
1.44
1.30
2.3
2.5
321.26
5470.33
umol/l
1.30
38
321
151
1381
1.47
1.30
5.1
5.2
38.12
39.35
mmol/mol
1.37
141
1299
5
18
2.82
1.29
1.0
1.3
—
—
—
0
0
155
1426
1.50
1.28
17.1
11.6
86.12
84.71
ml/min/173m2
0.36
137
1164
28
191
1.55
1.23
2.1
2.3
24.34
23.02
%
0.24
22
165
32
229
1.48
1.13
2.9
2.3
1.50
1.05
e6/l
0.32
17
128
7
34
2.10
1.04
1.7
2.8
0.00
0.00
g/l
—
7
34
15
92
1.69
1.00
1.1
1.0
—
—
—
0
0
18
265
0.65
0.97
2.2
2.8
0.63
0.75
ug/l
—
10
165
7
37
1.93
0.95
6.0
1.4
—
—
—
0
0
171
1629
1.55
0.93
21.0
14.1
75.83
74.86
umol/l
0.16
171
1629
6
28
2.18
0.92
1.2
1.1
—
—
—
0
0
35
266
1.39
0.91
1.3
1.3
1.22
7.72
u/ml
1.99
16
108
15
97
1.59
0.84
4.3
3.8
119.80
77.86
ng/l
—
10
90
8
48
1.70
0.80
1.1
1.3
—
1.74
—
0
9
9
53
1.73
0.76
1.6
2.5
—
—
—
0
0
5
24
2.11
0.75
1.6
1.4
—
—
—
0
0
47
387
1.29
0.73
1.5
1.7
1.46
1.41
mmol/l
0.15
29
333
118
1081
1.25
0.73
3.7
3.4
—
—
—
0
0
7
40
1.78
0.72
1.6
1.1
—
—
—
0
0
7
43
1.65
0.67
1.1
1.3
—
45.38
—
0
6
5
28
1.81
0.66
1.6
1.5
—
—
—
0
0
46
383
1.27
0.66
3.9
3.7
17.55
10.96
mg/mmol
0.21
27
249
7
44
1.61
0.66
2.0
2.4
2.96
3.40
g/l
—
7
44
10
63
1.62
0.63
1.4
2.0
—
—
—
0
0
0
21
0.00
0.60
0.0
2.0
—
13.35
—
0
21
153
1456
1.27
0.60
3.6
3.8
1.29
1.27
mmol/l
0.09
135
1350
18
132
1.40
0.59
2.9
2.3
0.21
0.23
g/l
0.33
18
123
11
160
0.67
0.58
2.1
1.6
—
—
—
0
0
6
35
1.74
0.58
1.2
1.3
—
—
—
0
0
8
54
1.50
0.58
2.9
3.3
9.38
246.18
u/ml
—
8
44
20
152
1.35
0.55
10.2
6.7
103.40
103.93
mmol/l
0.13
20
152
33
272
1.26
0.52
1.5
1.5
—
—
—
0
0
27
324
0.81
0.43
2.3
2.0
—
—
—
0
0
159
1535
1.23
0.43
4.5
4.6
2.71
2.82
mmol/l
0.84
139
1430
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
15
115
1.33
0.40
1.3
1.2
262.37
133.62
iu/ml
—
6
47
76
696
1.15
0.40
2.3
2.3
—
—
—
0
0
5
35
1.44
0.39
1.2
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.7
—
—
—
0
0
13
98
1.35
0.38
1.3
1.3
—
—
—
0
0
30
256
1.20
0.36
5.0
3.2
184.52
117.45
ng/l
0.25
21
182
155
1504
1.17
0.32
4.1
4.2
1.44
1.47
mmol/l
0.45
137
1404
177
1738
1.31
0.32
26.7
18.2
39.97
40.46
%
0.44
167
1648
7
53
1.33
0.31
1.4
2.2
93.86
92.74
%
—
7
53
7
54
1.31
0.31
1.7
1.6
—
—
—
0
0
28
321
0.85
0.29
1.4
1.7
—
—
—
0
0
155
1511
1.15
0.25
4.2
4.2
4.57
4.72
mmol/l
1.09
138
1421
19
161
1.20
0.25
10.4
7.1
—
—
—
0
0
5
41
1.23
0.22
1.6
1.5
—
—
—
0
0
5
41
1.23
0.22
2.4
2.5
—
—
—
0
0
5
41
1.23
0.22
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
6.90
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
207.65
—
0
12
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
52
1.16
0.19
2.5
1.4
53.83
82.94
pmol/l
—
6
52
24
214
1.14
0.18
2.2
2.0
—
—
—
0
0
11
91
1.22
0.18
2.1
1.6
—
—
—
0
0
22
197
1.13
0.16
2.2
1.8
—
—
—
0
0
33
357
0.91
0.15
3.9
4.3
23.72
20.64
%
0.60
16
157
47
442
1.08
0.15
4.1
4.6
1.94
1.91
ug/l
0.03
38
392
5
46
1.09
0.09
1.0
1.6
39.10
39.20
nmol/l
—
5
46
6
56
1.07
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
5
63
0.79
0.08
2.6
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
12
120
1.00
-0.00
2.2
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
19.47
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
2.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_ABNORMAL_REFLEX – Abnormal reflex
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).