This is a non-core endpoint: only basic statistics are computed.
Abnormal reflex
R18_ABNORMAL_REFLEX
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
181 |
4. Check minimum number of eventsNone |
181 |
5. Include endpointsNone |
181 |
6. Filter based on genotype QC (FinnGen only) |
181 |
Control definitions (FinnGen only)
- Control exclude
- CD2_BENIGN_FEMALE_GEN_OTH
Extra metadata
- Level in the ICD hierarchy
- 4
- Special
- INCREASEDREFLEXES
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R29
- Name in latin
- Reflexus abnormis
Similar endpoints
↥List of similar endpoints to
Abnormal reflex
based on the number of shared cases.
Similar with more cases:
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 181 | 108 | 73 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | 50.26 | 45.93 | 56.67 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 163
- Matched controls
- 1628
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R29.2
ICD-10 Finland
Abnormal reflex
+∞
232.5
162
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
12.9
30.1
57
65
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.8
15.1
31
38
TAB00
NOMESCO Finland
Lumbar puncture
8.9
10.5
22
28
R20.2
ICD-10 Finland
Paraesthesia of skin
6.7
9.8
25
43
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
12.5
9.8
17
15
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.1
9.1
29
66
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
13.8
8.5
14
11
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
8.3
26
58
N03AX12
ATC
gabapentin; oral
3.2
7.4
41
153
AA1AD
NOMESCO Finland
CT of head and brain
2.8
7.3
53
237
J45.9
ICD-10 Finland
Asthma, unspecified
3.1
6.4
37
142
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
18.9
6.3
9
5
F33.8
ICD-10 Finland
Other recurrent depressive disorders
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
18
30
6.55
10.61
2.8
2.4
16.58
15.84
%
—
5
11
42
145
3.47
10.23
5.0
3.5
—
—
—
0
0
34
103
3.83
10.04
4.3
3.9
1.21
1.23
mmol/l
1.43
27
93
19
38
5.47
9.32
7.4
2.7
5.04
5.01
kpa
0.06
19
38
31
93
3.82
9.25
6.0
5.5
25.63
25.22
mmol/l
0.26
31
93
16
33
5.22
7.56
1.3
1.2
1.50
2.14
e6/l
—
10
28
59
290
2.53
7.39
1.7
1.7
137778213.31
463.20
pmol/l
0.49
45
246
10
14
7.50
6.77
1.1
1.1
—
—
—
0
0
118
810
2.31
6.65
5.0
4.4
6.54
6.58
mmol/l
0.10
111
749
110
751
2.18
6.05
5.8
5.8
10.07
10.87
umol/l
0.65
104
717
61
332
2.26
5.91
1.9
1.7
0.69
1.28
mg/l
1.94
45
268
10
17
6.17
5.69
1.1
1.2
—
—
—
0
0
80
495
2.10
5.55
3.6
2.9
—
—
—
0
0
97
645
2.09
5.55
7.0
6.5
1.21
1.21
mmol/l
0.43
70
540
46
228
2.36
5.50
2.1
1.6
1562.10
1235.07
nmol/l
1.14
30
174
33
141
2.64
5.38
2.3
2.1
334.89
373.79
nmol/l
0.55
28
133
87
565
2.04
5.21
5.0
3.6
—
—
—
0
0
101
697
2.02
5.06
4.6
3.5
0.00
0.00
estimate
0.00
35
138
66
401
2.02
4.65
5.2
3.8
0.00
0.01
estimate
0.50
35
137
100
705
1.94
4.54
5.8
4.7
0.00
0.01
estimate
0.50
36
136
101
715
1.93
4.52
4.7
3.5
0.00
0.00
estimate
0.00
36
131
64
395
1.96
4.25
3.6
2.5
0.65
0.39
e6/l
0.34
51
292
82
562
1.84
3.88
2.2
2.4
76.01
74.66
nmol/l
0.17
73
511
85
594
1.81
3.74
7.4
5.6
1.20
1.22
mmol/l
1.03
76
549
53
322
1.91
3.62
2.2
2.0
2.71
2.92
mg/l
0.40
43
282
158
1353
2.32
3.62
5.5
4.5
1.58
2.77
mu/l
0.74
150
1248
137
1119
1.92
3.51
5.0
3.8
15.34
14.63
pmol/l
2.79
128
1034
135
1111
1.85
3.20
4.9
3.7
10.80
10.18
mm/h
0.20
128
1038
67
455
1.75
3.13
3.2
2.4
47.67
54.39
u/l
1.56
60
431
38
222
1.90
2.87
3.1
3.0
0.82
0.82
mmol/l
0.04
30
211
73
519
1.68
2.84
5.5
3.9
45.35
44.05
ng/l
0.02
55
338
8
18
4.60
2.83
1.1
1.2
—
—
—
0
0
53
346
1.75
2.80
1.2
1.3
0.72
1.64
u/ml
1.23
18
104
5
6
8.52
2.76
1.6
1.2
—
—
%
—
0
0
6
10
6.16
2.72
1.2
1.0
—
—
—
0
0
30
167
1.95
2.61
6.8
5.4
1.10
1.03
mmol/l
1.20
25
156
134
1129
1.72
2.60
8.4
6.9
75.12
78.84
u/l
0.59
125
1058
5
7
7.30
2.56
7.0
2.9
—
—
—
0
0
166
1499
2.30
2.54
19.0
12.4
21.99
21.67
mg/l
0.04
138
1185
18
83
2.30
2.50
1.3
1.3
—
—
—
0
0
13
53
2.57
2.33
1.5
1.3
—
—
—
0
0
6
13
4.73
2.29
1.0
1.1
—
—
—
0
0
9
29
3.21
2.26
2.6
3.3
56.11
58.14
%
—
9
29
124
1046
1.59
2.18
4.2
2.9
47.62
45.72
u/l
0.11
112
994
105
855
1.54
2.14
7.6
9.2
3.83
4.12
e9/l
0.92
93
747
11
43
2.66
2.14
1.9
1.3
—
—
—
0
0
14
62
2.36
2.13
1.3
1.8
—
—
—
0
0
8
26
3.17
2.04
1.6
1.3
—
—
—
0
0
13
57
2.38
2.03
4.2
2.7
0.55
0.74
%
1.68
13
57
6
16
3.84
1.95
3.5
3.6
102.33
107.81
mmol/l
—
6
16
32
201
1.72
1.91
2.4
2.6
4.75
2.13
e6/l
0.52
15
102
11
46
2.48
1.89
1.4
1.4
0.22
0.23
g/l
0.27
11
46
25
147
1.81
1.86
1.6
1.7
—
—
—
0
0
25
147
1.81
1.86
1.7
1.7
—
—
—
0
0
32
206
1.67
1.75
2.1
1.9
1.47
1.49
%
0.05
26
180
12
55
2.27
1.71
2.7
1.9
54.74
6607.91
u/l
—
5
14
7
26
2.76
1.59
1.1
1.1
—
—
—
0
0
66
513
1.45
1.56
2.0
1.8
87.53
96.89
pmol/l
1.08
40
268
18
101
1.87
1.55
1.8
1.5
—
—
—
0
0
5
15
3.40
1.53
1.0
1.1
—
—
—
0
0
75
600
1.43
1.52
6.0
4.1
36.27
36.04
g/l
0.14
68
570
51
380
1.48
1.49
2.8
3.1
1311.22
821.01
ng/l
0.36
42
303
10
45
2.29
1.49
1.4
1.1
—
—
—
0
0
153
1402
1.59
1.45
4.5
4.3
5.74
5.84
mmol/l
0.68
143
1299
5
16
3.18
1.45
1.0
1.3
—
—
—
0
0
169
1592
1.93
1.39
11.9
9.4
26.77
25.94
u/l
0.30
162
1546
30
202
1.58
1.39
1.8
1.8
—
—
—
0
0
62
486
1.42
1.38
2.7
3.3
2.33
2.35
mmol/l
0.88
57
434
79
647
1.39
1.37
3.6
2.7
98.19
102.97
ug/l
0.11
71
604
47
352
1.45
1.33
2.3
2.4
321.26
5653.97
umol/l
1.30
38
310
15
86
1.81
1.23
1.1
1.0
—
—
—
0
0
149
1372
1.49
1.22
17.3
11.8
85.71
84.12
ml/min/173m2
0.41
132
1120
27
186
1.53
1.14
2.1
2.3
25.02
22.91
%
0.43
21
160
145
1338
1.42
1.08
5.0
5.3
38.08
39.34
mmol/mol
1.37
135
1260
37
276
1.43
1.07
1.4
1.3
23.23
27.21
iu/ml
0.18
15
98
7
34
2.10
1.04
6.0
1.4
—
—
—
0
0
31
226
1.45
1.01
2.8
2.3
1.59
1.05
e6/l
0.38
16
127
15
92
1.69
1.00
4.3
3.7
119.80
78.01
ng/l
—
10
85
5
23
2.21
0.98
1.6
1.4
—
—
—
0
0
34
255
1.41
0.96
1.2
1.3
1.22
7.84
u/ml
1.99
16
106
6
28
2.18
0.92
1.2
1.1
—
—
—
0
0
18
259
0.66
0.88
2.2
2.8
0.63
0.76
ug/l
—
10
163
8
47
1.73
0.82
1.6
2.4
8.46
10.65
g/l
—
8
41
6
34
1.79
0.77
1.8
2.8
0.00
0.00
g/l
—
6
34
113
1029
1.26
0.77
3.6
3.4
—
—
—
0
0
164
1572
1.46
0.73
21.3
14.3
76.29
75.13
umol/l
0.19
164
1572
33
259
1.34
0.72
1.5
1.4
—
—
—
0
0
5
26
1.95
0.71
1.6
1.6
—
—
—
0
0
10
153
0.63
0.66
2.2
1.7
—
—
—
0
0
45
374
1.27
0.66
1.5
1.7
1.48
1.40
mmol/l
0.26
28
321
7
44
1.61
0.66
2.0
2.4
2.96
3.40
g/l
—
7
44
0
21
0.00
0.60
0.0
2.0
—
13.35
—
0
21
8
52
1.56
0.60
1.6
2.4
—
—
—
0
0
148
1408
1.28
0.60
3.6
3.8
1.29
1.28
mmol/l
0.14
130
1304
8
53
1.53
0.59
2.9
3.3
9.38
251.84
u/ml
—
8
43
44
371
1.25
0.57
4.3
3.9
18.21
11.32
mg/mmol
0.22
26
240
9
59
1.55
0.56
1.4
2.0
—
—
—
0
0
147
1401
1.26
0.55
17.4
12.7
39.75
40.30
%
0.28
96
1084
13
92
1.45
0.52
1.3
1.3
—
—
—
0
0
7
48
1.48
0.47
1.1
1.3
—
1.74
—
0
9
154
1487
1.24
0.42
4.6
4.6
2.69
2.82
mmol/l
1.01
134
1382
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
5
35
1.44
0.39
1.2
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.7
—
—
—
0
0
16
126
1.30
0.36
3.1
2.3
0.22
0.23
g/l
0.24
16
117
6
43
1.41
0.35
1.2
1.3
—
45.38
—
0
6
29
249
1.20
0.33
5.1
3.3
184.52
120.39
ng/l
0.23
21
177
6
47
1.29
0.32
1.8
2.5
3.18
3.06
g/l
—
6
36
27
313
0.84
0.32
2.3
2.0
—
—
—
0
0
7
52
1.36
0.31
1.4
2.2
93.86
92.46
%
—
7
52
7
52
1.36
0.31
1.7
1.5
—
—
—
0
0
150
1456
1.18
0.31
4.1
4.2
1.44
1.47
mmol/l
0.37
132
1356
19
159
1.22
0.28
10.4
7.1
—
—
—
0
0
72
673
1.12
0.26
3.9
3.8
—
—
—
0
0
150
1463
1.15
0.24
4.2
4.3
4.56
4.72
mmol/l
1.18
133
1374
5
39
1.29
0.23
1.6
1.6
—
—
—
0
0
5
39
1.29
0.23
1.6
1.6
—
—
—
0
0
5
40
1.26
0.22
2.4
2.5
—
—
—
0
0
5
40
1.26
0.22
1.8
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
210.80
—
0
11
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
6
52
1.16
0.19
1.0
1.1
—
—
—
0
0
6
53
1.14
0.19
1.0
1.1
—
—
—
0
0
22
196
1.14
0.17
1.9
2.0
—
—
—
0
0
46
432
1.09
0.15
4.1
4.7
1.97
1.93
ug/l
0.03
37
382
20
179
1.13
0.15
1.9
1.9
—
—
—
0
0
9
108
0.82
0.13
2.7
1.7
—
—
—
0
0
28
299
0.92
0.10
1.4
1.6
—
—
—
0
0
5
44
1.14
0.10
1.0
1.6
39.10
39.68
nmol/l
—
5
44
33
347
0.94
0.08
3.9
4.3
23.72
20.73
%
0.58
16
155
6
71
0.84
0.08
2.3
1.5
—
—
—
0
0
8
83
0.96
0.00
2.4
1.5
—
—
—
0
0
5
50
1.00
0.00
2.8
1.4
54.80
84.14
pmol/l
—
5
50
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
5
59
0.84
0.00
2.6
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_ABNORMAL_REFLEX – Abnormal reflex
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).