hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.
Pre-eclampsia superimposed on chronic hypertension
DOID EFO Endpoint Browser PheWeb
O15_PREECLAMPS_CHRONIC_HYPERT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
209 |
4. Check minimum number of eventsNone |
209 |
5. Include endpointsNone |
209 |
6. Filter based on genotype QC (FinnGen only) |
209 |
Control definitions (FinnGen only)
- Control exclude
- O15_OEDEM_PROTUR_HYPERT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O10-O16
- Name in latin
- Hypertensio prae-existens cum proteinuria superposita
Similar endpoints
↥List of similar endpoints to Pre-eclampsia superimposed on chronic hypertension based on the number of shared cases.
Similar with more cases:
- Pre-eclampsia or eclampsia
- Pre-eclampsia or poor fetal growth
- Pregnancy hypertension
- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Delivery, wide proxy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1336 | 1336 | - |
Only index persons | 1325 | 1325 | - |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.04 | - |
Only index persons | 0.05 | 0.05 | - |
Median age at first event (years) | |||
Whole population | - | 32.55 | - |
Only index persons | - | 32.55 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 209 | 209 | - |
Unadjusted period prevalence (%) | 0.07 | 0.07 | - |
Median age at first event (years) | 33.08 | 33.08 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 194
- Matched controls
- 1940
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint O15_PREECLAMPS_CHRONIC_HYPERT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_PREECLAMPS_CHRONIC_HYPERT.N-year risk | Females | Males |
---|---|---|
1 | No data | No data |
5 | No data | No data |
10 | No data | No data |
15 | No data | No data |
20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_PREECLAMPS_CHRONIC_HYPERT – Pre-eclampsia superimposed on chronic hypertension
GWS hits: -