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Ehlers-Danlos syndrome

EFO Endpoint Browser PheWeb

Q17_EHLER_SYNDR

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q79.6
  • Cause of death: ICD-10 — Q79.6

2 out of 7 registries used, show all original rules.

360

4. Check minimum number of events

None

360

5. Include endpoints

None

360

6. Filter based on genotype QC (FinnGen only)

360

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1733 1378 348
Only index persons 1680 1355 325
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.01
Only index persons 0.04 0.05 0.01
Median age at first event (years)
Whole population 32.55 34.95 23.09
Only index persons 32.80 35.06 23.41

-FinnGen-

Key figures

All Female Male
Number of individuals 360 327 33
Unadjusted period prevalence (%) 0.10 0.11 0.01
Median age at first event (years) 37.43 37.99 31.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
313
Matched controls
3128
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
+∞
323.0
313
*
M35.7
ICD-10 Finland
Hypermobility syndrome
88.2
140.4
152
33
Z31.5
ICD-10 Finland
Genetic counselling
19.4
81.2
132
113
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
13.3
51.1
95
99
R4120
NOMESCO Finland
Occupational therapy
13.6
49.1
90
90
N03AX12
ATC
gabapentin; oral
8.3
48.2
123
226
N03AX16
ATC
pregabalin; oral
6.3
44.2
147
384
L28
ICPC
Limited function/disability (L)
9.3
44.0
101
153
N06AX21
ATC
duloxetine; oral
7.5
42.6
115
224
N02AX02
ATC
tramadol; systemic, rectal
5.0
39.0
187
715
M25.5
ICD-10 Finland
Pain in joint
5.0
37.7
171
610
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
9.7
33.1
71
92
SPAT1229
SPAT
Assessment of need for aid
13.5
33.0
59
53
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.4
31.9
83
146
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
6.1
30.5
94
207
L99
ICPC
Musculoskeletal disease other
27.6
30.1
41
17
K07.60
ICD-10 Finland
Snapping jaw
8.0
29.0
70
109
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.0
27.2
60
80
M79.7
ICD-10 Finland
Fibromyalgia
10.3
26.6
54
62
R4110
NOMESCO Finland
Physiotherapy
4.1
26.5
132
472
M79.0
ICD-10 Finland
Rheumatism, unspecified
12.2
26.4
49
47
A28
ICPC
Limited function/disability NOS
8.9
25.8
57
76
R03AC02
ATC
salbutamol; inhalant
3.8
25.6
230
1326
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
4.1
25.4
126
444
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.2
24.8
86
212
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
9.6
24.3
51
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.2
24.3
70
138
R52.2
ICD-10 Finland
Other chronic pain
14.6
24.2
41
32
N02AA05
ATC
oxycodone; systemic
7.0
24.0
63
109
M54.5
ICD-10 Finland
Low back pain
3.4
22.8
163
759
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
19.9
22.8
34
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
22.6
180
906
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
4.2
22.4
100
315
XF404
NOMESCO Finland
Ambulatory ECG
7.1
22.2
57
95
A02BC05
ATC
esomeprazole; systemic
3.3
22.2
166
795
A03FA01
ATC
metoclopramide; systemic, rectal
3.9
21.7
106
361
G93.3
ICD-10 Finland
Postviral fatigue syndrome
36.7
21.5
27
8
M03BX01
ATC
baclofen; systemic
15.6
21.4
35
25
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
16.4
21.2
34
23
C01CA24
ATC
epinephrine; parenteral
5.5
21.0
67
148
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.6
20.9
120
464
G43.9
ICD-10 Finland
Migraine, unspecified
5.5
20.8
66
145
R51.80
ICD-10 Finland
Headache
3.7
20.7
108
386
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.2
20.7
70
165
N06AA09
ATC
amitriptyline; systemic
6.0
20.5
60
119
M79.1
ICD-10 Finland
Myalgia
4.1
20.2
89
274
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
20.0
90
282
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
4.8
19.7
71
179
M54.4
ICD-10 Finland
Lumbago with sciatica
3.9
19.5
93
306
Z01.8
ICD-10 Finland
Other specified special examinations
3.5
19.2
109
413
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
19.1
111
428
N06AX16
ATC
venlafaxine; oral
3.7
19.0
96
331
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
6.1
18.8
54
104
G44.2
ICD-10 Finland
Tension-type headache
3.8
18.7
90
298
M79.6
ICD-10 Finland
Pain in limb
3.0
18.3
154
767
R06.0
ICD-10 Finland
Dyspnoea
3.6
18.2
99
359
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.9
18.1
42
60
J45.9
ICD-10 Finland
Asthma, unspecified
3.7
17.7
88
297
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.9
17.7
180
1005
R06AE07
ATC
cetirizine; oral
2.9
17.7
194
1134
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.0
17.4
59
138
C07AB07
ATC
bisoprolol; oral
3.1
17.3
120
519
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
4.5
17.3
66
175
A02BA02
ATC
ranitidine; systemic
3.9
17.3
79
248
M24.2
ICD-10 Finland
Disorder of ligament
18.8
17.2
26
15
H02AB06
ATC
prednisolone; systemic
2.8
17.0
172
945
Z50.1
ICD-10 Finland
Other physical therapy
8.3
17.0
38
51
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
16.6
16.5
26
17
A01
ICPC
Pain general/multiple sites
5.1
16.4
54
122
G44.0
ICD-10 Finland
Cluster headache syndrome
26.2
16.2
22
9
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.5
16.1
43
75
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
16.1
52
115
SPAT1215
SPAT
Assessment of need for medical rehabilitation
7.3
16.0
39
60
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
15.9
131
627
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.7
15.8
171
966
UKC02
NOMESCO Finland
Cystoscopy
5.0
15.5
52
120
N03AE01
ATC
clonazepam; systemic
6.5
15.5
41
71
XA800
NOMESCO Finland
Neuropsychological investigation
7.7
15.4
36
52
C07AA05
ATC
propranolol; systemic
3.0
15.3
111
489
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.0
15.1
66
197
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
15.1
144
749
N05AH04
ATC
quetiapine; oral
3.2
15.0
95
378
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.4
15.0
46
96
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
19.6
14.9
22
12
XKD00
NOMESCO Finland
Uroflowmetry
6.9
14.6
37
60
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
14.6
88
339
SPAT1231
SPAT
Assessment of adjustments needed in living environment
38.0
14.6
18
5
SBB10
NOMESCO Finland
Teeth copy
4.4
14.6
55
143
N04BC05
ATC
pramipexole; oral
7.0
14.5
36
57
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.9
14.4
41
78
UJF32
NOMESCO Finland
Coloscopy
3.2
14.4
87
336
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
4.0
14.4
62
183
A02BC02
ATC
pantoprazole; systemic
2.6
14.3
211
1384
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
14.1
84
320
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.3
14.0
31
41
N04BC09
ATC
rotigotine; transdermal
56.0
13.9
16
*
M01AH01
ATC
celecoxib; oral (coxibs)
3.6
13.8
68
224
J01FA10
ATC
azithromycin; systemic
2.7
13.8
239
1700
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
6.5
13.8
36
61
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.8
13.7
47
111
H02AB07
ATC
prednisone; oral
3.6
13.7
68
226
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
17.2
13.7
21
13
SPAT1216
SPAT
Assessment of functional ability
4.1
13.6
56
158
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.3
13.5
42
89
WX002
NOMESCO Finland
Sedation and analgesia
3.3
13.5
77
283
R42
ICD-10 Finland
Dizziness and giddiness
3.1
13.3
82
319
R51.81
ICD-10 Finland
Facial pain NOS
10.0
13.3
26
28
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
3.1
13.2
83
327
N02BE01
ATC
paracetamol; systemic, rectal
3.4
12.9
279
2219
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
12.9
161
946
R02
ICPC
Shortness of breath/dyspnoea
3.8
12.8
57
172
M54.2
ICD-10 Finland
Cervicalgia
4.4
12.7
47
120
R53
ICD-10 Finland
Malaise and fatigue
2.8
12.6
97
433
M25.2
ICD-10 Finland
Flail joint
14.0
12.6
21
16
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
12.6
132
702
L29
ICPC
Musculoskeletal sympt/complt other
4.9
12.6
42
96
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.0
12.6
52
147
N03AX09
ATC
lamotrigine; oral
4.8
12.6
43
101
M54.6
ICD-10 Finland
Pain in thoracic spine
4.5
12.6
46
116
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.2
12.5
49
132
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
12.4
113
555
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
6.2
12.3
33
58
C08DA01
ATC
verapamil; systemic
8.8
12.3
26
32
M89.0
ICD-10 Finland
Algoneurodystrophy
16.8
12.3
19
12
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.9
12.3
85
355
A06AC01
ATC
ispaghula (psylla seeds); oral
2.9
12.2
85
356
M02AA07
ATC
piroxicam; topical
2.6
12.1
113
562
R20.2
ICD-10 Finland
Paraesthesia of skin
4.3
12.0
46
121
R5599
NOMESCO Finland
Other rehabilitation service
10.2
12.0
23
24
M01AH02
ATC
rofecoxib; oral
4.0
11.9
49
138
M01AE03
ATC
ketoprofen; systemic, rectal
2.5
11.9
123
647
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
11.8
62
214
T78.4
ICD-10 Finland
Allergy, unspecified
4.4
11.8
44
113
R03DC03
ATC
montelukast; oral
2.9
11.7
84
355
R06AX27
ATC
desloratadine; oral
2.4
11.7
137
766
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
11.7
46
124
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
9.8
11.7
23
25
N81.6
ICD-10 Finland
Rectocele
6.0
11.7
32
58
P01AB01
ATC
metronidazole; oral, rectal
2.3
11.7
156
933
J01EA01
ATC
trimethoprim; systemic
2.6
11.5
108
534
Q76.9
ICD-10 Finland
Congenital malformation of bony thorax, unspecified
+∞
11.5
11
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.8
11.4
51
154
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.2
11.4
64
232
J45
ICD-10 Finland
Asthma
3.6
11.4
54
172
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.2
11.3
43
113
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
21.0
11.2
16
8
B02AA02
ATC
tranexamic acid; systemic
2.8
11.1
82
356
XA402
NOMESCO Finland
ENMG
8.8
11.0
23
28
JG1JB
NOMESCO Finland
Defekography with X-ray
45.0
11.0
13
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.7
10.9
31
59
XQ800
NOMESCO Finland
Prick test
3.5
10.9
53
172
Z71.8
ICD-10 Finland
Other specified counselling
2.4
10.8
112
583
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
18.7
10.8
16
9
S43.0
ICD-10 Finland
Dislocation of shoulder joint
7.5
10.8
25
36
N05BA01
ATC
diazepam; systemic, rectal
3.4
10.8
55
185
M03BC51
ATC
orphenadrine, combinations; systemic
2.4
10.8
112
585
F45.8
ICD-10 Finland
Other somatoform disorders
3.3
10.8
59
208
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.3
10.8
59
208
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.9
10.8
35
78
A04AA01
ATC
ondansetron; systemic, rectal
5.2
10.8
33
69
N06AX11
ATC
mirtazapine; oral
2.4
10.7
122
667
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.5
10.7
96
465
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.4
10.6
55
187
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
8.2
10.6
23
30
M01AH05
ATC
etoricoxib; oral
2.2
10.6
199
1371
N03AX11
ATC
topiramate; oral
5.9
10.6
29
53
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.6
10.5
30
58
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
33.8
10.4
13
*
M53.2
ICD-10 Finland
Spinal instabilities
33.8
10.4
13
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
10.4
92
441
R00.2
ICD-10 Finland
Palpitations
3.7
10.3
46
139
R06AX22
ATC
ebastine; oral
2.6
10.2
86
398
3007
Kela drug reimbursment
Erenumab and fremanezumab
11.9
10.2
18
16
G54.0
ICD-10 Finland
Brachial plexus disorders
5.4
10.2
30
60
N02CC05
ATC
almotriptan; oral
4.2
10.2
39
103
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.3
10.1
131
756
G47.3
ICD-10 Finland
Sleep apnoea
2.9
10.1
67
268
R35
ICD-10 Finland
Polyuria
7.1
10.1
24
36
M47.82
ICD-10 Finland
Other spondylosis, cervical region
8.1
10.1
22
29
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.7
10.1
34
79
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.2
10.0
55
194
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.2
10.0
55
194
R03BA02
ATC
budesonide; inhalant
2.7
10.0
80
358
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.8
10.0
43
126
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.5
10.0
29
57
J01FF01
ATC
clindamycin; systemic
2.4
9.9
99
501
A02BC01
ATC
omeprazole; systemic
2.5
9.9
89
429
J01FA06
ATC
roxithromycin; oral
2.2
9.9
149
918
M22.0
ICD-10 Finland
Recurrent dislocation of patella
7.2
9.8
23
34
ZXA05
NOMESCO Finland
Left side
2.7
9.8
74
322
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.4
9.8
48
157
G50.1
ICD-10 Finland
Atypical facial pain
10.5
9.6
18
18
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
9.6
120
675
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
9.6
78
351
N02CC03
ATC
zolmitriptan; nasal, oral
3.5
9.6
46
147
R55
ICD-10 Finland
Syncope and collapse
4.5
9.6
34
83
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.3
9.6
35
88
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.6
101
524
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
9.6
168
1101
R1250
NOMESCO Finland
Evaluation of functional capability
8.0
9.6
21
28
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.6
91
448
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
9.5
35
89
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
18.2
9.5
14
8
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.3
9.5
116
648
L12
ICPC
Hand/finger symptom/complaint
2.8
9.4
65
268
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
9.4
57
216
U07
ICPC
Urine symptom/complaint other
5.0
9.3
29
62
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.9
9.3
25
45
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.3
9.2
47
158
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
8.7
9.2
19
23
M50.3
ICD-10 Finland
Other cervical disc degeneration
10.5
9.1
17
17
A02BC03
ATC
lansoprazole; oral
2.4
9.1
93
475
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
16.2
9.1
14
9
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
16.2
9.1
14
9
R52.1
ICD-10 Finland
Chronic intractable pain
19.3
9.0
13
7
J01AA02
ATC
doxycycline; systemic
2.3
9.0
244
1908
ZX120
NOMESCO Finland
Intravenous
3.6
9.0
40
121
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.2
9.0
49
171
R11
ICD-10 Finland
Nausea and vomiting
3.3
8.9
45
150
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
8.9
42
133
J45.1
ICD-10 Finland
Nonallergic asthma
4.0
8.9
35
95
N02CD01
ATC
erenumab; parenteral
14.6
8.8
14
10
R03BA05
ATC
fluticasone; inhalant
2.4
8.8
82
397
K59.01
ICD-10 Finland
Constipation outlet obstruction type
51.5
8.7
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
8.7
73
334
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.7
8.7
63
266
R5140
NOMESCO Finland
Monitoring the use of the aid
3.7
8.7
37
108
M22.1
ICD-10 Finland
Recurrent subluxation of patella
16.9
8.6
13
8
G81.9
ICD-10 Finland
Hemiplegia, unspecified
16.9
8.6
13
8
R01AD09
ATC
mometasone; nasal
2.0
8.6
176
1209
M01AC06
ATC
meloxicam; systemic, rectal
2.2
8.6
110
620
N05CD07
ATC
temazepam; oral
4.2
8.6
32
83
R50.9
ICD-10 Finland
Fever, unspecified
2.7
8.5
62
263
A02BA03
ATC
famotidine; systemic
7.0
8.5
20
30
R52.9
ICD-10 Finland
Pain, unspecified
3.4
8.5
42
138
AA1AD
NOMESCO Finland
CT of head and brain
2.7
8.5
61
255
N05CF01
ATC
zopiclone; oral
2.3
8.5
96
512
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
8.4
132
813
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
5.2
8.4
25
51
L02
ICPC
Back symptom/complaint
3.1
8.4
48
175
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
9.9
8.4
16
17
H04.10
ICD-10 Finland
Dry eye syndrome
3.2
8.4
46
161
M22.4
ICD-10 Finland
Chondromalacia patellae
4.6
8.4
28
65
N02CC07
ATC
frovatriptan; oral
3.7
8.4
36
106
G43.3
ICD-10 Finland
Complicated migraine
6.0
8.3
22
39
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
8.3
46
163
C03CA01
ATC
furosemide; systemic
3.3
8.3
42
141
M03BX02
ATC
tizanidine; oral
2.1
8.2
217
1637
N02CC04
ATC
rizatriptan; oral
3.2
8.2
45
158
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
12.1
8.2
14
12
R51
ICD-10 Finland
Headache
3.5
8.1
37
114
R5110
SPAT
NA
10.4
8.1
15
15
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.6
8.1
62
269
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
8.1
56
228
PD5BD
NOMESCO Finland
Extensive CT of aorta
22.7
8.1
11
5
D07AD01
ATC
clobetasol; topical
2.7
8.0
59
251
K59.09
ICD-10 Finland
Constipation, unspecified
4.9
8.0
25
54
N80.9
ICD-10 Finland
Endometriosis, unspecified
5.7
8.0
22
41
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.1
8.0
24
50
R15
ICD-10 Finland
Faecal incontinence
8.8
7.9
16
19
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
9.8
7.9
15
16
M01AE02
ATC
naproxen; oral, rectal
2.0
7.8
206
1535
UJF92
NOMESCO Finland
Capsular endoscopy
6.7
7.8
19
30
C09CA06
ATC
candesartan; oral
2.5
7.8
68
317
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.6
7.8
61
269
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
7.8
75
369
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
7.8
38
124
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
46.1
7.8
9
*
Z01.9
ICD-10 Finland
Special examination, unspecified
4.6
7.7
26
61
L17
ICPC
Foot/toe symptom/complaint
2.2
7.7
86
453
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
7.7
44
160
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.1
7.7
29
76
J01DA01
ATC
[U] cefalexin; systemic
2.0
7.7
209
1571
R06AX26
ATC
fexofenadine; oral
3.3
7.7
39
131
WX110
NOMESCO Finland
Local anesthesy
2.1
7.7
245
1965
F50.9
ICD-10 Finland
Eating disorder, unspecified
6.5
7.7
19
31
N06AB06
ATC
sertraline; oral
2.5
7.7
62
277
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
6.0
7.7
20
35
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
18.9
7.7
11
6
N06BA04
ATC
methylphenidate; oral
4.7
7.6
25
57
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
9.2
7.6
15
17
N03AF01
ATC
carbamazepine; oral, rectal
5.1
7.6
23
48
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
5.1
7.6
23
48
SAA02
NOMESCO Finland
Basic examination of mouth
2.2
7.6
248
1999
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.6
7.6
33
98
N06AA10
ATC
nortriptyline; systemic
7.4
7.6
17
24
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.0
7.5
199
1474
R06AE09
ATC
levocetirizine; oral
2.4
7.5
71
347
N06BA12
ATC
lisdexamfetamine; oral
13.8
7.4
12
9
G43
ICD-10 Finland
Migraine
3.1
7.4
41
144
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.5
7.4
25
59
R60.0
ICD-10 Finland
Localized oedema
3.5
7.4
34
106
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
7.4
55
234
F84.5
ICD-10 Finland
Asperger syndrome
11.2
7.4
13
12
N06AX17
ATC
milnacipran; oral
9.7
7.4
14
15
A04
ICPC
Weakness/tiredness general
2.5
7.4
60
268
R03BA01
ATC
beclometasone; inhalant
2.6
7.3
53
224
J02AC01
ATC
fluconazole; systemic
1.9
7.3
174
1234
N05BA04
ATC
oxazepam; oral
2.2
7.3
89
487
Q79.9
ICD-10 Finland
Congenital malformation of musculoskeletal system, unspecified
+∞
7.3
7
*
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
7.3
7
*
N03AG01
ATC
valproic acid; systemic, rectal
3.6
7.3
32
96
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
7.3
29
80
J01DB01
ATC
cefalexin; oral
2.4
7.3
272
2303
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
5.5
7.2
20
38
J45.8
ICD-10 Finland
Mixed asthma
5.9
7.2
19
34
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
30.8
7.2
9
*
7183F
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, POLVI]
30.8
7.2
9
*
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
20.6
7.2
10
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
7.1
73
369
J20
ICD-10 Finland
Acute bronchitis
3.1
7.1
40
143
R13
ICD-10 Finland
Dysphagia
4.5
7.1
24
57
L19
ICPC
Muscle symptom/complaint NOS
7.3
7.1
16
23
ZXA10
NOMESCO Finland
Bilateral
2.4
7.1
62
291
R07.3
ICD-10 Finland
Other chest pain
3.3
7.1
34
110
F34.1
ICD-10 Finland
Dysthymia
4.1
7.1
26
67
SPAT1240
SPAT
Therapeutic discussion
2.4
7.1
63
295
S18
ICPC
Laceration/cut
2.0
7.0
111
674
XG466
NOMESCO Finland
Sleep oxymetry
6.6
7.0
17
27
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.6
7.0
17
27
J01MA12
ATC
levofloxacin; systemic
2.6
7.0
53
227
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
5.0
7.0
21
44
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
7.8
7.0
15
20
A06AD11
ATC
lactulose; oral
3.4
7.0
32
100
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
14.2
6.9
11
8
XF402
NOMESCO Finland
ECG with work load test
3.8
6.9
28
79
SPAT1284
SPAT
Extensive health certificate
5.5
6.9
19
36
H02AB09
ATC
hydrocortisone; systemic
5.9
6.9
18
32
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
11.3
6.9
12
11
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
11.3
6.9
12
11
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
9.6
6.8
13
14
WZA90
NOMESCO Finland
Other doctors statement
2.1
6.8
89
498
M01AX05
ATC
glucosamine; oral
3.3
6.8
34
113
E0000UV
ATC
NA
1.9
6.8
142
954
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.7
6.8
28
80
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
5.1
6.8
20
41
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
7.4
6.8
15
21
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.8
68
338
J05AB11
ATC
valaciclovir; oral
2.6
6.8
50
214
N30.0
ICD-10 Finland
Acute cystitis
2.4
6.8
60
283
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.1
6.8
25
65
M43.1
ICD-10 Finland
Spondylolisthesis
5.4
6.7
19
37
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
6.7
6.7
16
25
R33
ICD-10 Finland
Retention of urine
5.7
6.7
18
33
G72.9
ICD-10 Finland
Myopathy, unspecified
23.1
6.7
9
*
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
23.1
6.7
9
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.1
6.7
17
29
G43.8
ICD-10 Finland
Other migraine
8.1
6.7
14
18
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
8.1
6.7
14
18
G04CA02
ATC
tamsulosin; oral
4.6
6.7
22
51
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
6.7
48
200
JAH01
NOMESCO Finland
Laparoscopy
3.6
6.7
29
87
TKC20
NOMESCO Finland
Catheterisation of bladder
4.2
6.6
24
61
H03AA01
ATC
levothyroxine sodium; systemic
2.1
6.6
86
480
W19
ICD-10 Finland
Unspecified fall
3.3
6.6
32
104
N06AB04
ATC
citalopram; systemic
2.1
6.6
79
427
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.7
6.6
21
47
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
6.6
112
694
N06AX22
ATC
agomelatine; oral
4.5
6.6
22
52
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.8
6.6
42
165
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.3
6.5
23
57
G47.9
ICD-10 Finland
Sleep disorder, unspecified
5.9
6.5
17
30
XCK00
NOMESCO Finland
Perimetry
4.1
6.5
24
62
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.9
6.5
39
147
L20
ICPC
Joint symptom/complaint NOS
4.6
6.5
21
48
J31.0
ICD-10 Finland
Chronic rhinitis
3.0
6.5
37
135
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.0
6.5
37
135
R03BA08
ATC
ciclesonide; inhalant
2.9
6.5
38
142
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
71.2
6.4
7
*
R4190
NOMESCO Finland
Nutritional therapy
4.2
6.4
23
58
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
6.4
104
635
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
6.4
186
1388
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
6.4
36
129
N81.1
ICD-10 Finland
Cystocele
4.8
6.4
20
44
R05
ICD-10 Finland
Cough
2.3
6.4
62
305
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
6.4
64
320
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
4.5
6.4
21
49
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.5
6.4
28
85
9243
FHL
Plastic of the patella and its tendons
11.3
6.3
11
10
M47.9
ICD-10 Finland
Spondylosis, unspecified
11.3
6.3
11
10
NBE35
NOMESCO Finland
Transposition of ligament of shoulder, arthroscopic
11.3
6.3
11
10
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
11.3
6.3
11
10
C03DA01
ATC
spironolactone; oral
4.0
6.3
24
64
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
6.3
181
1340
L16
ICPC
Ankle symptom/complaint
2.7
6.3
43
174
TKD00
NOMESCO Finland
Dilatation of urethra
18.5
6.3
9
5
1220
FHL
Arthroscopy
5.2
6.3
18
36
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.2
6.3
18
36
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.7
6.3
20
45
J01AA07
ATC
tetracycline; systemic
2.1
6.3
73
389
WX402
NOMESCO Finland
General anaesthesia
2.2
6.3
65
328
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
+∞
6.3
6
*
Z82.6
ICD-10 Finland
Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
+∞
6.3
6
*
H02AA02
ATC
fludrocortisone; oral
27.3
6.3
8
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
27.3
6.3
8
*
NA3BM
NOMESCO Finland
Lumbar spine MRI examination with 3 Tesla magnet
27.3
6.3
8
*
X58
ICD-10 Finland
Exposure to other specified factors
2.3
6.2
58
277
L03
ICPC
Low back symptom/complaint
2.0
6.2
91
532
L13
ICPC
Hip symptom/complaint
2.7
6.2
42
169
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
6.2
94
558
G56.2
ICD-10 Finland
Lesion of ulnar nerve
5.1
6.2
18
37
SPAT1059
SPAT
Spirometry at the office
4.1
6.1
22
56
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
12.9
6.1
10
8
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
12.9
6.1
10
8
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.4
6.1
28
88
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
6.1
138
944
J01MA02
ATC
ciprofloxacin; systemic
1.9
6.1
107
668
B99
ICD-10 Finland
Other and unspecified infectious diseases
10.3
6.1
11
11
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
10.3
6.1
11
11
I34.1
ICD-10 Finland
Mitral (valve) prolapse
10.3
6.1
11
11
M54.3
ICD-10 Finland
Sciatica
3.7
6.1
25
72
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.4
6.1
51
234
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.1
57
273
SPAT1260
SPAT
Consultation of another employee
2.3
6.1
60
298
N06AX12
ATC
bupropion; oral
2.7
6.1
39
154
K59.1
ICD-10 Finland
Functional diarrhoea
3.8
6.0
24
67
R06AX13
ATC
loratadine; oral
2.1
6.0
73
395

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
228
1127
3.79
33.26
6.9
5.5
1.2
1.2
mmol/l
1.44
191
964
137
493
3.87
32.31
1.6
1.4
338.0
540.6
titre
1.12
20
105
207
1000
3.52
30.49
6.8
4.9
1.2
1.2
mmol/l
2.11
191
921
160
664
3.54
29.98
2.2
1.9
150.9
228.5
u/l
0.34
153
636
233
1225
3.56
29.66
3.2
2.3
76.6
73.0
nmol/l
1.17
217
1139
189
904
3.30
27.53
2.4
1.7
96.6
96.4
pmol/l
0.02
113
506
104
342
3.87
27.46
3.1
2.6
0.8
0.8
mmol/l
0.73
92
323
155
661
3.36
27.31
3.2
3.6
7.4
7.4
ph
0.47
27
119
94
296
3.94
26.31
2.1
2.0
350.7
383.2
nmol/l
0.86
79
278
163
733
3.24
26.03
4.6
2.6
649.9
72.6
e6/l
0.58
137
537
125
488
3.39
25.11
3.2
2.3
6.8
10.5
e6/l
1.12
111
422
62
147
4.89
25.10
1.3
1.3
0.2
1.8
u/ml
—
6
6
185
922
3.07
24.29
6.6
5.3
—
—
—
0
0
146
647
3.11
23.43
4.7
2.5
0.1
0.3
e6/l
3.41
120
458
149
670
3.09
23.28
4.6
2.5
—
—
—
0
0
186
946
3.00
23.28
5.5
3.0
78.0
43.4
e6/l
0.27
145
592
144
646
3.05
22.45
5.2
3.0
99.7
98.6
%
0.24
139
630
84
281
3.59
21.16
3.1
2.3
25.7
24.3
%
0.40
74
242
97
356
3.36
21.13
3.4
2.2
15.4
14.7
umol/l
0.45
89
328
97
358
3.34
20.92
3.9
2.2
6.0
4.4
e6/l
0.44
53
175
302
2101
3.71
20.25
8.7
6.2
68.8
72.7
u/l
1.06
284
1982
236
1439
2.86
19.90
5.8
3.9
6.0
6.3
mmol/l
1.23
225
1284
242
1509
2.84
19.29
7.7
5.2
0.5
0.5
e9/l
0.12
222
1334
235
1445
2.80
19.23
7.7
5.4
7.5
7.8
%
0.63
228
1363
240
1493
2.82
19.17
7.3
5.0
55.6
56.7
%
0.80
233
1409
234
1438
2.79
19.13
7.4
5.2
2.6
2.6
%
0.03
226
1344
242
1517
2.82
18.95
7.7
5.3
0.0
0.0
e9/l
0.01
222
1338
114
487
2.96
18.92
5.3
3.8
—
—
—
0
0
148
737
2.71
18.24
7.4
5.3
1.1
1.1
inr
0.21
53
262
239
1508
2.74
18.14
7.4
5.2
30.7
29.7
%
0.93
232
1422
225
1380
2.68
18.05
7.5
5.3
0.6
0.6
%
0.17
217
1285
87
327
3.19
17.97
3.2
2.1
2.4
2.5
g/l
0.37
78
298
17
13
13.68
17.79
3.5
3.4
374.4
569.5
u/ml
0.42
17
13
262
1743
2.85
17.71
3.2
2.7
—
—
—
0
0
245
1578
2.73
17.62
7.7
5.2
2.0
2.0
e9/l
0.46
228
1419
71
239
3.45
17.51
1.4
1.2
215.9
234.6
u/ml
0.05
66
219
244
1575
2.70
17.35
7.8
5.7
0.2
0.2
e9/l
0.17
227
1413
112
494
2.84
17.33
2.4
2.4
80.3
88.4
ug/g
0.15
84
386
107
462
2.87
17.22
3.7
2.3
521.1
563.5
mosm/kgh2o
1.04
95
395
258
1735
2.72
16.49
9.4
7.9
4.1
4.0
e9/l
0.46
238
1514
290
2074
3.05
16.37
5.7
3.7
—
—
—
0
0
279
1958
2.89
16.27
6.4
3.8
633.4
839.0
e6/l
—
5
27
84
329
3.03
16.02
2.0
1.6
1031.1
1116.9
nmol/l
0.31
69
260
170
950
2.50
16.01
4.4
4.3
36.8
37.1
g/l
0.37
162
898
299
2209
3.09
15.21
5.3
3.6
8.7
8.8
mm/h
0.11
280
2079
134
691
2.50
14.77
3.2
2.1
2.5
2.8
mg/l
1.56
113
596
152
844
2.39
14.09
2.8
2.9
2.3
2.3
mmol/l
1.02
136
767
224
1479
2.36
13.76
4.2
3.1
0.0
0.0
estimate
0.00
51
307
21
31
7.13
13.73
1.4
1.3
—
—
—
0
0
208
1335
2.32
13.60
5.6
4.9
9.5
9.7
umol/l
0.14
198
1253
82
345
2.78
13.55
1.3
1.2
—
—
—
0
0
222
1468
2.34
13.48
5.7
4.3
0.0
0.0
estimate
0.50
48
316
351
3079
6.60
12.86
19.9
9.8
16.3
18.4
mg/l
0.91
294
2327
220
1469
2.28
12.77
4.2
3.0
0.0
0.0
estimate
0.00
49
308
83
366
2.65
12.43
2.7
2.6
1051.8
153.0
ng/l
0.73
37
174
104
511
2.46
12.42
1.7
1.4
19.3
20.8
nmol/l
0.46
95
456
139
783
2.26
12.07
3.5
2.8
13.4
21.0
ng/l
0.96
53
328
48
159
3.33
11.98
5.5
8.4
1.1
1.2
mmol/l
0.13
35
122
63
248
2.87
11.69
3.3
2.5
31.0
32.7
u/l
0.11
55
206
130
722
2.25
11.60
7.6
6.1
—
—
—
0
0
75
327
2.63
11.43
1.9
2.0
—
—
—
0
0
198
1305
2.15
11.38
10.8
7.6
0.0
0.0
e9/l
0.34
172
1061
116
625
2.26
11.05
1.5
1.3
32.9
28.0
iu/ml
0.09
28
197
63
256
2.77
10.99
2.6
2.1
26.6
16.5
au/ml
—
5
16
193
1272
2.12
10.96
2.2
1.9
—
—
—
0
0
46
158
3.19
10.80
5.7
8.4
14.4
13.7
kpa
0.24
46
152
46
158
3.19
10.80
5.7
8.5
5.0
5.1
kpa
0.57
46
152
138
806
2.15
10.69
3.8
2.4
49.5
55.1
u/l
1.58
128
751
16
23
7.23
10.66
24.6
2.2
—
—
—
0
0
31
83
3.99
10.55
1.6
1.4
321.1
320.2
ug/g
0.01
14
46
29
74
4.17
10.52
1.7
2.2
—
—
—
0
0
92
466
2.31
10.03
1.6
1.5
196053087.8
19302753.1
pmol/l
0.43
76
430
238
1731
2.11
10.00
4.5
2.9
63.7
59.6
ug/l
0.41
219
1644
39
128
3.30
9.85
16.5
8.6
—
—
—
0
0
16
26
6.39
9.54
1.1
2.8
1.6
1.3
e9/l
—
11
8
58
243
2.65
9.49
4.9
3.9
4.8
4.7
pmol/l
0.23
50
219
134
809
2.05
9.25
1.9
1.4
2.1
2.0
g/l
0.11
84
520
50
198
2.77
9.11
3.2
2.5
0.2
0.2
g/l
0.27
45
189
312
2570
2.61
9.10
5.8
4.4
14.2
14.3
pmol/l
0.07
290
2417
11
12
9.42
9.02
1.2
2.3
—
—
—
0
0
38
132
3.10
8.74
6.4
8.7
125.2
119.8
g/l
0.86
38
127
10
10
10.26
8.68
1.1
1.0
—
—
—
0
0
116
680
2.04
8.57
3.0
1.7
0.8
0.8
mg/l
0.01
85
495
69
329
2.36
8.55
1.6
1.4
—
—
—
0
0
108
618
2.07
8.51
1.5
1.3
2.1
11.7
u/ml
2.29
36
262
109
628
2.06
8.42
4.2
2.8
—
—
—
0
0
14
23
6.29
8.24
27.6
1.9
70.8
63.3
%
0.64
14
23
48
196
2.67
8.23
2.0
2.6
1.5
1.8
%
2.01
41
174
41
154
2.88
8.22
12.3
3.1
—
—
—
0
0
140
894
1.93
7.99
2.8
1.9
—
—
—
0
0
20
48
4.35
7.84
1.7
2.0
178.4
176.1
ug/l
0.01
13
40
45
184
2.65
7.69
1.6
1.9
—
—
—
0
0
25
72
3.66
7.69
1.3
1.3
—
—
—
0
0
27
82
3.48
7.68
7.6
10.7
0.7
0.7
%
0.33
27
82
71
358
2.22
7.67
1.2
1.2
—
—
—
0
0
39
149
2.81
7.58
12.9
3.1
1.5
2.1
mmol/l
0.47
30
108
44
180
2.65
7.51
7.7
9.5
1.0
1.3
inr
—
8
39
20
50
4.18
7.45
1.8
2.1
8.6
8.3
kpa
0.37
20
43
16
34
4.88
7.23
1.9
1.7
—
—
—
0
0
33
118
2.98
7.22
1.3
1.7
—
—
—
0
0
69
355
2.17
7.07
1.8
1.4
21.7
23.5
iu/l
0.16
55
306
334
2930
2.94
7.03
6.8
5.0
1.5
2.1
mu/l
0.84
320
2789
320
2756
2.45
6.92
3.7
3.3
5.5
5.6
mmol/l
0.27
292
2585
26
83
3.30
6.86
8.0
10.6
1.1
1.5
%
0.80
26
83
122
782
1.85
6.65
4.1
4.0
—
—
—
0
0
71
378
2.09
6.64
2.3
2.4
2.4
2.4
mmol/l
0.05
60
326
60
300
2.20
6.58
2.7
2.2
4.7
5.7
umol/l
0.34
50
247
106
654
1.88
6.49
3.8
3.0
1.0
1.0
kg/l
0.37
14
96
25
81
3.24
6.45
8.2
10.8
94.3
94.1
%
0.05
25
81
25
82
3.20
6.32
3.2
4.9
—
—
—
0
0
97
586
1.90
6.32
3.1
2.7
—
—
—
0
0
65
341
2.11
6.30
1.4
1.3
79.4
179.8
iu/ml
2.43
28
146
122
798
1.80
6.14
4.9
2.2
—
—
—
0
0
11
19
5.94
6.14
1.3
2.5
—
—
—
0
0
38
160
2.54
6.12
2.0
3.5
1.2
1.2
mmol/l
0.61
29
138
349
3184
4.15
5.95
12.5
8.0
24.2
23.8
u/l
0.21
343
3105
135
918
1.75
5.91
1.4
1.3
0.7
1.2
u/ml
1.19
31
246
43
196
2.36
5.85
1.2
1.2
—
—
—
0
0
5
0
+∞
5.22
3.2
0.0
83.0
—
umol/l
—
5
0
30
124
2.55
5.03
2.5
2.4
70.0
77.4
e9/l
0.70
25
90
26
100
2.72
5.01
1.7
2.1
40.3
91.4
ng/l
1.73
19
85
113
764
1.70
4.89
4.7
3.2
0.0
0.0
estimate
0.50
50
314
12
28
4.40
4.86
1.2
1.3
—
—
—
0
0
13
33
4.05
4.75
1.2
1.2
—
—
—
0
0
20
490
0.37
4.71
1.4
1.3
—
—
—
0
0
129
912
1.65
4.67
3.4
2.7
—
—
—
0
0
27
111
2.55
4.59
1.5
2.2
11.1
4.0
ug/l
0.50
27
99
10
21
4.87
4.56
1.3
1.1
—
—
—
0
0
29
124
2.46
4.54
3.6
2.7
5.4
5.1
kpa
1.26
29
111
8
8
10.19
4.54
1.0
1.3
—
—
iu/ml
—
0
0
14
39
3.69
4.53
1.3
1.3
—
—
—
0
0
55
306
1.94
4.50
1.3
1.3
—
—
—
0
0
97
642
1.70
4.50
1.9
3.0
8.0
8.2
mmol/l
0.08
84
566
23
88
2.72
4.49
4.5
6.8
23.8
24.4
mmol/l
0.47
23
83
45
235
2.05
4.40
1.3
1.5
—
—
—
0
0
37
180
2.18
4.33
2.4
2.2
—
—
—
0
0
25
102
2.56
4.32
1.2
1.2
—
—
—
0
0
34
160
2.24
4.31
1.5
1.4
—
—
—
0
0
26
109
2.49
4.25
1.2
2.0
—
—
—
0
0
15
46
3.36
4.23
2.7
4.2
2.1
1.2
mmol/l
1.11
15
46
29
129
2.36
4.18
1.9
1.7
—
—
—
0
0
47
254
1.98
4.18
1.3
1.5
—
—
—
0
0
17
57
3.08
4.18
2.2
1.6
1.0
1.5
ug/l
0.19
17
52
53
299
1.91
4.17
1.5
1.3
—
—
—
0
0
47
255
1.97
4.14
1.3
1.5
—
—
—
0
0
12
32
3.84
4.12
1.7
1.9
—
—
—
0
0
40
205
2.07
4.11
1.4
1.5
—
—
—
0
0
47
256
1.96
4.09
1.3
1.5
—
—
—
0
0
59
352
1.81
3.89
2.3
2.2
6528.5
3714.3
u/l
0.34
18
152
40
211
2.01
3.81
1.1
1.1
—
—
—
0
0
38
197
2.04
3.80
3.0
4.2
0.0
0.0
%
—
7
43
7
8
8.89
3.79
1.0
1.0
—
—
—
0
0
40
212
2.00
3.76
2.9
4.0
0.4
0.8
%
—
8
53
32
157
2.14
3.69
3.5
3.2
—
—
—
0
0
45
252
1.90
3.62
1.3
1.5
—
—
—
0
0
180
1437
1.51
3.59
4.4
3.9
—
—
—
0
0
16
57
2.89
3.57
2.2
1.6
—
—
—
0
0
44
246
1.90
3.56
1.4
1.6
300.0
313.9
mu/l
0.15
37
222
22
93
2.45
3.56
1.1
1.0
10.7
6.4
u/ml
0.35
15
50
46
262
1.87
3.52
4.6
3.1
—
—
—
0
0
6
6
10.14
3.51
1.2
1.0
—
—
—
0
0
6
6
10.14
3.51
1.2
1.0
—
—
—
0
0
6
6
10.14
3.51
1.2
1.0
—
—
—
0
0
12
36
3.41
3.51
1.1
1.2
—
—
—
0
0
38
203
1.97
3.51
2.9
4.1
0.0
0.1
%
—
7
48
348
3277
2.86
3.44
15.9
9.1
—
—
—
0
0
10
27
3.78
3.37
1.1
1.1
22.6
31.6
mg/l
—
10
21
23
102
2.34
3.37
1.1
1.1
—
—
—
0
0
8
14
5.82
3.36
1.1
1.1
—
—
—
0
0
280
2474
1.59
3.33
4.2
4.0
35.7
37.4
mmol/mol
3.34
258
2365
15
54
2.86
3.29
5.6
4.0
—
—
—
0
0
8
15
5.43
3.21
1.9
2.1
—
—
—
0
0
7
11
6.46
3.20
5.3
2.1
14.4
12.2
%
—
7
11
30
153
2.05
3.15
1.3
1.3
10.2
10.9
u/l
0.11
22
125
36
198
1.91
3.07
2.4
3.9
0.0
0.7
%
—
6
38
55
346
1.70
3.02
1.2
1.2
—
—
—
0
0
20
88
2.35
2.99
1.1
1.0
0.9
0.6
u/ml
0.19
11
42
22
102
2.23
2.93
1.2
1.1
1.7
1.3
u/ml
0.10
14
41
16
64
2.57
2.91
1.3
1.6
—
—
—
0
0
7
13
5.47
2.88
1.0
1.5
132.9
129.3
nmol/l
—
7
13
39
229
1.79
2.73
3.2
3.7
—
—
—
0
0
9
25
3.66
2.59
1.2
1.1
—
—
—
0
0
48
304
1.67
2.58
1.6
1.2
—
—
—
0
0
15
62
2.48
2.57
1.3
1.3
—
—
—
0
0
21
102
2.12
2.52
1.2
1.2
—
—
—
0
0
16
69
2.38
2.52
1.4
1.2
—
—
—
0
0
8
21
3.87
2.47
1.3
1.7
—
—
—
0
0
17
77
2.27
2.41
1.5
1.1
—
—
—
0
0
8
22
3.69
2.37
1.4
1.4
—
—
—
0
0
17
78
2.24
2.35
10.6
9.9
—
—
—
0
0
10
35
2.91
2.32
1.1
1.1
—
—
nmol/l
—
0
0
16
72
2.28
2.31
1.3
1.6
2.1
123.1
e6/l
0.97
11
60
16
72
2.28
2.31
1.3
1.5
1.2
4.8
e6/l
1.46
11
56
6
13
4.67
2.28
1.0
1.0
—
—
—
0
0
21
107
2.02
2.25
1.6
1.5
0.3
0.4
nmol/l
1.08
16
92
82
607
1.45
2.23
1.8
2.1
294.3
3745.8
umol/l
2.05
73
557
7
19
3.74
2.16
1.1
1.7
—
—
—
0
0
11
44
2.55
2.03
1.1
1.3
—
—
—
0
0
9
32
2.86
2.01
1.3
1.3
—
—
—
0
0
27
157
1.78
1.99
1.3
1.2
—
—
—
0
0
7
21
3.38
1.97
4.0
1.5
—
—
—
0
0
6
16
3.79
1.94
1.8
1.4
—
—
—
0
0
6
16
3.79
1.94
1.8
1.4
—
—
—
0
0
6
16
3.79
1.94
1.8
1.4
—
—
—
0
0
6
16
3.79
1.94
1.8
1.4
—
—
—
0
0
18
326
0.53
1.91
1.2
1.7
—
—
—
0
0
7
22
3.22
1.89
1.0
1.1
—
—
—
0
0
17
86
2.03
1.88
4.8
3.0
—
—
—
0
0
13
59
2.25
1.86
2.9
4.1
48.5
58.2
%
1.70
13
59
19
102
1.91
1.80
2.3
2.2
—
—
—
0
0
14
68
2.10
1.72
1.1
1.4
—
—
—
0
0
6
19
3.19
1.67
1.2
1.0
—
—
—
0
0
7
25
2.83
1.65
1.7
1.8
92.6
91.6
%
—
7
25
11
49
2.28
1.65
1.9
2.4
25.1
24.7
mmol/l
0.20
11
40
12
56
2.18
1.63
1.1
1.0
—
—
—
0
0
21
125
1.72
1.47
2.1
1.5
—
—
—
0
0
12
59
2.07
1.45
3.2
3.7
3.3
4.5
e9/l
1.71
12
59
10
46
2.21
1.41
1.7
1.7
—
—
—
0
0
12
222
0.52
1.40
1.6
1.4
—
—
—
0
0
9
41
2.23
1.38
1.0
1.2
—
—
—
0
0
5
17
2.97
1.36
1.0
3.1
0.2
0.2
e9/l
—
5
17
19
113
1.72
1.34
1.8
2.0
2.8
6.3
iu/l
—
8
43
9
42
2.17
1.34
1.1
1.1
—
—
—
0
0
31
210
1.52
1.33
1.2
1.2
—
—
—
0
0
6
24
2.52
1.31
1.2
1.8
—
—
—
0
0
5
18
2.80
1.29
1.4
1.8
5.9
3.5
mg/l
—
5
18
5
18
2.80
1.29
1.0
1.4
—
—
—
0
0
13
228
0.55
1.29
1.6
1.4
—
—
—
0
0
25
163
1.57
1.27
1.1
1.1
—
—
—
0
0
12
63
1.94
1.24
1.1
1.3
107.7
131.1
u/ml
—
6
15
6
26
2.33
1.19
1.3
2.0
—
—
—
0
0
8
38
2.13
1.19
1.5
1.2
—
—
—
0
0
13
221
0.57
1.16
1.5
1.4
—
—
—
0
0
21
316
0.64
1.15
1.3
1.3
—
—
—
0
0
5
20
2.52
1.15
1.2
1.2
—
—
—
0
0
302
2874
1.32
1.12
3.7
3.5
3.0
2.9
mmol/l
1.14
280
2724
15
89
1.72
1.09
1.0
1.2
—
—
—
0
0
314
3007
1.35
1.09
20.6
10.3
40.1
39.9
%
0.22
259
2541
7
34
2.08
1.03
1.1
1.4
248.9
475.3
pmol/l
—
7
26
9
47
1.94
1.03
1.3
2.1
—
—
—
0
0
11
61
1.83
0.99
1.0
1.2
—
—
—
0
0
10
54
1.88
0.97
1.0
1.0
—
—
—
0
0
27
192
1.44
0.95
1.4
1.4
—
—
—
0
0
82
689
1.25
0.95
1.4
1.6
1.5
1.4
mmol/l
0.47
71
612
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
6
27
2.24
0.94
1.2
1.3
—
—
—
0
0
64
770
0.79
0.90
1.6
1.7
—
—
—
0
0
15
95
1.60
0.89
2.1
1.9
—
—
—
0
0
297
2844
1.25
0.87
3.4
3.3
1.5
1.5
mmol/l
1.18
277
2709
62
512
1.25
0.84
1.6
1.6
—
—
—
0
0
298
2858
1.25
0.84
3.6
3.3
4.8
4.8
mmol/l
0.39
283
2728
6
33
1.83
0.79
2.3
1.8
—
—
—
0
0
6
34
1.78
0.76
1.2
1.3
19.2
27.9
nmol/l
—
6
25
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
295
2835
1.22
0.75
23.8
12.2
332.6
332.6
g/l
0.04
295
2815
79
910
0.83
0.74
1.9
1.7
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
58
485
1.23
0.72
2.1
3.3
1241.2
220.7
mg/l
0.39
29
319
10
62
1.63
0.65
1.1
1.1
—
—
—
0
0
21
156
1.37
0.62
3.8
4.3
2.5
8.3
ug/l
1.20
16
119
59
504
1.20
0.61
2.4
4.0
5.3
12.9
mg/mmol
1.10
32
324
12
80
1.52
0.60
2.6
1.3
—
—
—
0
0
10
64
1.58
0.59
1.4
1.1
—
—
—
0
0
12
83
1.46
0.52
1.3
1.1
—
—
—
0
0
12
83
1.46
0.52
1.3
1.1
—
—
—
0
0
14
101
1.40
0.50
1.2
1.8
—
—
—
0
0
7
45
1.57
0.49
3.0
2.3
—
—
—
0
0
114
1226
0.90
0.41
2.1
2.1
—
—
—
0
0
7
102
0.68
0.40
1.9
2.4
2.6
4.8
umol/l
—
7
76
39
449
0.85
0.38
1.4
2.1
—
—
—
0
0
12
89
1.36
0.38
6.9
5.9
—
—
—
0
0
36
315
1.16
0.31
1.9
1.4
—
—
—
0
0
7
97
0.72
0.31
1.0
1.2
—
—
—
0
0
278
2722
1.09
0.27
3.3
3.0
1.3
1.2
mmol/l
1.26
261
2587
5
38
1.32
0.23
1.0
2.4
2.5
2.8
u/ml
—
5
32
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
27.4
—
6.8
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
6
50
1.20
0.20
1.0
1.0
—
—
—
0
0
14
119
1.18
0.18
1.5
1.4
52.6
68.7
pmol/l
0.77
14
114
23
205
1.13
0.17
1.4
1.3
—
—
—
0
0
25
226
1.11
0.15
2.0
2.4
3.0
4.2
e9/l
3.12
19
197
55
579
0.94
0.13
1.6
1.5
—
—
—
0
0
107
1063
1.01
0.01
1.6
1.8
—
—
—
0
0
113
1129
1.00
0.00
2.1
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
1.2
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
14.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_EHLER_SYNDR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_EHLER_SYNDR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: Q17_EHLER_SYNDR – Ehlers-Danlos syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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