No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
360 |
4. Check minimum number of eventsNone |
360 |
5. Include endpointsNone |
360 |
6. Filter based on genotype QC (FinnGen only) |
360 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Ehlers-Danlos syndrome
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the musculoskeletal system, not elsewhere classified
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1733 | 1378 | 348 |
| Only index persons | 1680 | 1355 | 325 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.01 |
| Only index persons | 0.04 | 0.05 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 32.55 | 34.95 | 23.09 |
| Only index persons | 32.80 | 35.06 | 23.41 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 360 | 327 | 33 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.01 |
| Median age at first event (years) | 37.43 | 37.99 | 31.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 313
- Matched controls
- 3128
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
+∞
323.0
313
*
M35.7
ICD-10 Finland
Hypermobility syndrome
88.2
140.4
152
33
Z31.5
ICD-10 Finland
Genetic counselling
19.4
81.2
132
113
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
13.3
51.1
95
99
R4120
NOMESCO Finland
Occupational therapy
13.6
49.1
90
90
N03AX12
ATC
gabapentin; oral
8.3
48.2
123
226
N03AX16
ATC
pregabalin; oral
6.3
44.2
147
384
L28
ICPC
Limited function/disability (L)
9.3
44.0
101
153
N06AX21
ATC
duloxetine; oral
7.5
42.6
115
224
N02AX02
ATC
tramadol; systemic, rectal
5.0
39.0
187
715
M25.5
ICD-10 Finland
Pain in joint
5.0
37.7
171
610
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
9.7
33.1
71
92
SPAT1229
SPAT
Assessment of need for aid
13.5
33.0
59
53
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.4
31.9
83
146
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
6.1
30.5
94
207
L99
ICPC
Musculoskeletal disease other
27.6
30.1
41
17
K07.60
ICD-10 Finland
Snapping jaw
8.0
29.0
70
109
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.0
27.2
60
80
M79.7
ICD-10 Finland
Fibromyalgia
10.3
26.6
54
62
R4110
NOMESCO Finland
Physiotherapy
4.1
26.5
132
472
M79.0
ICD-10 Finland
Rheumatism, unspecified
12.2
26.4
49
47
A28
ICPC
Limited function/disability NOS
8.9
25.8
57
76
R03AC02
ATC
salbutamol; inhalant
3.8
25.6
230
1326
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
4.1
25.4
126
444
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.2
24.8
86
212
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
9.6
24.3
51
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.2
24.3
70
138
R52.2
ICD-10 Finland
Other chronic pain
14.6
24.2
41
32
N02AA05
ATC
oxycodone; systemic
7.0
24.0
63
109
M54.5
ICD-10 Finland
Low back pain
3.4
22.8
163
759
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
19.9
22.8
34
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
22.6
180
906
Z3226
NOMESCO Finland
Physiotherapist
4.1
22.5
103
332
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
4.2
22.4
100
315
XF404
NOMESCO Finland
Ambulatory ECG
7.1
22.2
57
95
A02BC05
ATC
esomeprazole; systemic
3.3
22.2
166
795
A03FA01
ATC
metoclopramide; systemic, rectal
3.9
21.7
106
361
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
7.7
21.6
52
79
G93.3
ICD-10 Finland
Postviral fatigue syndrome
36.7
21.5
27
8
M03BX01
ATC
baclofen; systemic
15.6
21.4
35
25
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
16.4
21.2
34
23
C01CA24
ATC
epinephrine; parenteral
5.5
21.0
67
148
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.6
20.9
120
464
G43.9
ICD-10 Finland
Migraine, unspecified
5.5
20.8
66
145
R51.80
ICD-10 Finland
Headache
3.7
20.7
108
386
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.2
20.7
70
165
N06AA09
ATC
amitriptyline; systemic
6.0
20.5
60
119
M79.1
ICD-10 Finland
Myalgia
4.1
20.2
89
274
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
20.0
90
282
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
4.8
19.7
71
179
M54.4
ICD-10 Finland
Lumbago with sciatica
3.9
19.5
93
306
ZY010
NOMESCO Finland
Hospital outpatient
6.2
19.5
55
104
Z01.8
ICD-10 Finland
Other specified special examinations
3.5
19.2
109
413
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
19.1
111
428
N06AX16
ATC
venlafaxine; oral
3.7
19.0
96
331
Z2445
NOMESCO Finland
Psychologist
7.1
19.0
48
78
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
6.1
18.8
54
104
G44.2
ICD-10 Finland
Tension-type headache
3.8
18.7
90
298
Z2446
NOMESCO Finland
Social worker
5.4
18.3
58
126
M79.6
ICD-10 Finland
Pain in limb
3.0
18.3
154
767
R06.0
ICD-10 Finland
Dyspnoea
3.6
18.2
99
359
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.9
18.1
42
60
J45.9
ICD-10 Finland
Asthma, unspecified
3.7
17.7
88
297
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.9
17.7
180
1005
R06AE07
ATC
cetirizine; oral
2.9
17.7
194
1134
Z3231
NOMESCO Finland
Registered nurse
3.2
17.5
118
500
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.0
17.4
59
138
C07AB07
ATC
bisoprolol; oral
3.1
17.3
120
519
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
4.5
17.3
66
175
A02BA02
ATC
ranitidine; systemic
3.9
17.3
79
248
M24.2
ICD-10 Finland
Disorder of ligament
18.8
17.2
26
15
H02AB06
ATC
prednisolone; systemic
2.8
17.0
172
945
Z50.1
ICD-10 Finland
Other physical therapy
8.3
17.0
38
51
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
16.6
16.5
26
17
A01
ICPC
Pain general/multiple sites
5.1
16.4
54
122
G44.0
ICD-10 Finland
Cluster headache syndrome
26.2
16.2
22
9
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.5
16.1
43
75
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
16.1
52
115
SPAT1215
SPAT
Assessment of need for medical rehabilitation
7.3
16.0
39
60
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
15.9
131
627
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.7
15.8
171
966
UKC02
NOMESCO Finland
Cystoscopy
5.0
15.5
52
120
N03AE01
ATC
clonazepam; systemic
6.5
15.5
41
71
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
15.4
136
675
XA800
NOMESCO Finland
Neuropsychological investigation
7.7
15.4
36
52
C07AA05
ATC
propranolol; systemic
3.0
15.3
111
489
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.0
15.1
66
197
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
15.1
144
749
N05AH04
ATC
quetiapine; oral
3.2
15.0
95
378
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.4
15.0
46
96
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
19.6
14.9
22
12
XKD00
NOMESCO Finland
Uroflowmetry
6.9
14.6
37
60
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
14.6
88
339
SPAT1231
SPAT
Assessment of adjustments needed in living environment
38.0
14.6
18
5
SBB10
NOMESCO Finland
Teeth copy
4.4
14.6
55
143
N04BC05
ATC
pramipexole; oral
7.0
14.5
36
57
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.9
14.4
41
78
UJF32
NOMESCO Finland
Coloscopy
3.2
14.4
87
336
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
4.0
14.4
62
183
A02BC02
ATC
pantoprazole; systemic
2.6
14.3
211
1384
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
14.1
84
320
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.3
14.0
31
41
N04BC09
ATC
rotigotine; transdermal
56.0
13.9
16
*
M01AH01
ATC
celecoxib; oral (coxibs)
3.6
13.8
68
224
J01FA10
ATC
azithromycin; systemic
2.7
13.8
239
1700
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
6.5
13.8
36
61
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.8
13.7
47
111
H02AB07
ATC
prednisone; oral
3.6
13.7
68
226
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
17.2
13.7
21
13
SPAT1216
SPAT
Assessment of functional ability
4.1
13.6
56
158
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.3
13.5
42
89
WX002
NOMESCO Finland
Sedation and analgesia
3.3
13.5
77
283
R42
ICD-10 Finland
Dizziness and giddiness
3.1
13.3
82
319
R51.81
ICD-10 Finland
Facial pain NOS
10.0
13.3
26
28
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
3.1
13.2
83
327
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.3
13.0
50
132
N02BE01
ATC
paracetamol; systemic, rectal
3.4
12.9
279
2219
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
12.9
161
946
R02
ICPC
Shortness of breath/dyspnoea
3.8
12.8
57
172
M54.2
ICD-10 Finland
Cervicalgia
4.4
12.7
47
120
R53
ICD-10 Finland
Malaise and fatigue
2.8
12.6
97
433
M25.2
ICD-10 Finland
Flail joint
14.0
12.6
21
16
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
12.6
132
702
L29
ICPC
Musculoskeletal sympt/complt other
4.9
12.6
42
96
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.0
12.6
52
147
N03AX09
ATC
lamotrigine; oral
4.8
12.6
43
101
M54.6
ICD-10 Finland
Pain in thoracic spine
4.5
12.6
46
116
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.2
12.5
49
132
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
12.4
113
555
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
6.2
12.3
33
58
C08DA01
ATC
verapamil; systemic
8.8
12.3
26
32
M89.0
ICD-10 Finland
Algoneurodystrophy
16.8
12.3
19
12
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.9
12.3
85
355
A06AC01
ATC
ispaghula (psylla seeds); oral
2.9
12.2
85
356
M02AA07
ATC
piroxicam; topical
2.6
12.1
113
562
R20.2
ICD-10 Finland
Paraesthesia of skin
4.3
12.0
46
121
R5599
NOMESCO Finland
Other rehabilitation service
10.2
12.0
23
24
M01AH02
ATC
rofecoxib; oral
4.0
11.9
49
138
M01AE03
ATC
ketoprofen; systemic, rectal
2.5
11.9
123
647
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
11.8
62
214
T78.4
ICD-10 Finland
Allergy, unspecified
4.4
11.8
44
113
R03DC03
ATC
montelukast; oral
2.9
11.7
84
355
R06AX27
ATC
desloratadine; oral
2.4
11.7
137
766
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
11.7
46
124
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
9.8
11.7
23
25
N81.6
ICD-10 Finland
Rectocele
6.0
11.7
32
58
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.7
11.7
40
94
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
8.0
11.7
26
35
P01AB01
ATC
metronidazole; oral, rectal
2.3
11.7
156
933
J01EA01
ATC
trimethoprim; systemic
2.6
11.5
108
534
Q76.9
ICD-10 Finland
Congenital malformation of bony thorax, unspecified
+∞
11.5
11
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.8
11.4
51
154
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.2
11.4
64
232
J45
ICD-10 Finland
Asthma
3.6
11.4
54
172
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.2
11.3
43
113
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
21.0
11.2
16
8
B02AA02
ATC
tranexamic acid; systemic
2.8
11.1
82
356
XA402
NOMESCO Finland
ENMG
8.8
11.0
23
28
JG1JB
NOMESCO Finland
Defekography with X-ray
45.0
11.0
13
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.7
10.9
31
59
Z2221
NOMESCO Finland
Medical doctor
2.4
10.9
121
653
XQ800
NOMESCO Finland
Prick test
3.5
10.9
53
172
Z71.8
ICD-10 Finland
Other specified counselling
2.4
10.8
112
583
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
18.7
10.8
16
9
S43.0
ICD-10 Finland
Dislocation of shoulder joint
7.5
10.8
25
36
N05BA01
ATC
diazepam; systemic, rectal
3.4
10.8
55
185
M03BC51
ATC
orphenadrine, combinations; systemic
2.4
10.8
112
585
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.3
10.8
59
208
F45.8
ICD-10 Finland
Other somatoform disorders
3.3
10.8
59
208
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.9
10.8
35
78
A04AA01
ATC
ondansetron; systemic, rectal
5.2
10.8
33
69
N06AX11
ATC
mirtazapine; oral
2.4
10.7
122
667
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.5
10.7
96
465
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.4
10.6
55
187
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
8.2
10.6
23
30
M01AH05
ATC
etoricoxib; oral
2.2
10.6
199
1371
N03AX11
ATC
topiramate; oral
5.9
10.6
29
53
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.6
10.5
30
58
M53.2
ICD-10 Finland
Spinal instabilities
33.8
10.4
13
*
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
33.8
10.4
13
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
10.4
92
441
R00.2
ICD-10 Finland
Palpitations
3.7
10.3
46
139
R06AX22
ATC
ebastine; oral
2.6
10.2
86
398
3007
Kela drug reimbursment
Erenumab and fremanezumab
11.9
10.2
18
16
G54.0
ICD-10 Finland
Brachial plexus disorders
5.4
10.2
30
60
N02CC05
ATC
almotriptan; oral
4.2
10.2
39
103
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.3
10.1
131
756
G47.3
ICD-10 Finland
Sleep apnoea
2.9
10.1
67
268
R35
ICD-10 Finland
Polyuria
7.1
10.1
24
36
M47.82
ICD-10 Finland
Other spondylosis, cervical region
8.1
10.1
22
29
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.7
10.1
34
79
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.2
10.0
55
194
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.2
10.0
55
194
R03BA02
ATC
budesonide; inhalant
2.7
10.0
80
358
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.8
10.0
43
126
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.5
10.0
29
57
J01FF01
ATC
clindamycin; systemic
2.4
9.9
99
501
A02BC01
ATC
omeprazole; systemic
2.5
9.9
89
429
J01FA06
ATC
roxithromycin; oral
2.2
9.9
149
918
M22.0
ICD-10 Finland
Recurrent dislocation of patella
7.2
9.8
23
34
ZXA05
NOMESCO Finland
Left side
2.7
9.8
74
322
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.4
9.8
48
157
G50.1
ICD-10 Finland
Atypical facial pain
10.5
9.6
18
18
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
9.6
120
675
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
9.6
78
351
N02CC03
ATC
zolmitriptan; nasal, oral
3.5
9.6
46
147
R55
ICD-10 Finland
Syncope and collapse
4.5
9.6
34
83
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.3
9.6
35
88
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.6
101
524
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
9.6
168
1101
R1250
NOMESCO Finland
Evaluation of functional capability
8.0
9.6
21
28
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.6
91
448
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
9.5
35
89
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
18.2
9.5
14
8
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.3
9.5
116
648
L12
ICPC
Hand/finger symptom/complaint
2.8
9.4
65
268
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
9.4
57
216
U07
ICPC
Urine symptom/complaint other
5.0
9.3
29
62
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.9
9.3
25
45
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.3
9.2
47
158
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
8.7
9.2
19
23
M50.3
ICD-10 Finland
Other cervical disc degeneration
10.5
9.1
17
17
A02BC03
ATC
lansoprazole; oral
2.4
9.1
93
475
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
16.2
9.1
14
9
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
16.2
9.1
14
9
R52.1
ICD-10 Finland
Chronic intractable pain
19.3
9.0
13
7
J01AA02
ATC
doxycycline; systemic
2.3
9.0
244
1908
ZX120
NOMESCO Finland
Intravenous
3.6
9.0
40
121
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.2
9.0
49
171
R11
ICD-10 Finland
Nausea and vomiting
3.3
8.9
45
150
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
8.9
42
133
J45.1
ICD-10 Finland
Nonallergic asthma
4.0
8.9
35
95
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
8.8
127
759
N02CD01
ATC
erenumab; parenteral
14.6
8.8
14
10
R03BA05
ATC
fluticasone; inhalant
2.4
8.8
82
397
K59.01
ICD-10 Finland
Constipation outlet obstruction type
51.5
8.7
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
8.7
73
334
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.7
8.7
63
266
R5140
NOMESCO Finland
Monitoring the use of the aid
3.7
8.7
37
108
M22.1
ICD-10 Finland
Recurrent subluxation of patella
16.9
8.6
13
8
G81.9
ICD-10 Finland
Hemiplegia, unspecified
16.9
8.6
13
8
R01AD09
ATC
mometasone; nasal
2.0
8.6
176
1209
M01AC06
ATC
meloxicam; systemic, rectal
2.2
8.6
110
620
N05CD07
ATC
temazepam; oral
4.2
8.6
32
83
R50.9
ICD-10 Finland
Fever, unspecified
2.7
8.5
62
263
A02BA03
ATC
famotidine; systemic
7.0
8.5
20
30
R52.9
ICD-10 Finland
Pain, unspecified
3.4
8.5
42
138
AA1AD
NOMESCO Finland
CT of head and brain
2.7
8.5
61
255
N05CF01
ATC
zopiclone; oral
2.3
8.5
96
512
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
8.4
132
813
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
5.2
8.4
25
51
L02
ICPC
Back symptom/complaint
3.1
8.4
48
175
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
9.9
8.4
16
17
H04.10
ICD-10 Finland
Dry eye syndrome
3.2
8.4
46
161
M22.4
ICD-10 Finland
Chondromalacia patellae
4.6
8.4
28
65
N02CC07
ATC
frovatriptan; oral
3.7
8.4
36
106
G43.3
ICD-10 Finland
Complicated migraine
6.0
8.3
22
39
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
8.3
46
163
C03CA01
ATC
furosemide; systemic
3.3
8.3
42
141
M03BX02
ATC
tizanidine; oral
2.1
8.2
217
1637
N02CC04
ATC
rizatriptan; oral
3.2
8.2
45
158
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
12.1
8.2
14
12
R51
ICD-10 Finland
Headache
3.5
8.1
37
114
R5110
SPAT
NA
10.4
8.1
15
15
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.6
8.1
62
269
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
8.1
56
228
PD5BD
NOMESCO Finland
Extensive CT of aorta
22.7
8.1
11
5
D07AD01
ATC
clobetasol; topical
2.7
8.0
59
251
K59.09
ICD-10 Finland
Constipation, unspecified
4.9
8.0
25
54
N80.9
ICD-10 Finland
Endometriosis, unspecified
5.7
8.0
22
41
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.1
8.0
24
50
R15
ICD-10 Finland
Faecal incontinence
8.8
7.9
16
19
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
9.8
7.9
15
16
M01AE02
ATC
naproxen; oral, rectal
2.0
7.8
206
1535
UJF92
NOMESCO Finland
Capsular endoscopy
6.7
7.8
19
30
C09CA06
ATC
candesartan; oral
2.5
7.8
68
317
ZYC01
NOMESCO Finland
Remote contact by phone
4.4
7.8
27
65
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.6
7.8
61
269
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
7.8
75
369
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
7.8
38
124
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
46.1
7.8
9
*
Z01.9
ICD-10 Finland
Special examination, unspecified
4.6
7.7
26
61
L17
ICPC
Foot/toe symptom/complaint
2.2
7.7
86
453
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
7.7
44
160
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.1
7.7
29
76
J01DA01
ATC
[U] cefalexin; systemic
2.0
7.7
209
1571
R06AX26
ATC
fexofenadine; oral
3.3
7.7
39
131
WX110
NOMESCO Finland
Local anesthesy
2.1
7.7
245
1965
F50.9
ICD-10 Finland
Eating disorder, unspecified
6.5
7.7
19
31
N06AB06
ATC
sertraline; oral
2.5
7.7
62
277
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
6.0
7.7
20
35
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
18.9
7.7
11
6
N06BA04
ATC
methylphenidate; oral
4.7
7.6
25
57
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
12.3
7.6
13
11
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
9.2
7.6
15
17
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
5.1
7.6
23
48
N03AF01
ATC
carbamazepine; oral, rectal
5.1
7.6
23
48
SAA02
NOMESCO Finland
Basic examination of mouth
2.2
7.6
248
1999
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.6
7.6
33
98
N06AA10
ATC
nortriptyline; systemic
7.4
7.6
17
24
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.0
7.5
199
1474
R06AE09
ATC
levocetirizine; oral
2.4
7.5
71
347
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.8
7.5
31
89
N06BA12
ATC
lisdexamfetamine; oral
13.8
7.4
12
9
G43
ICD-10 Finland
Migraine
3.1
7.4
41
144
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.5
7.4
25
59
R60.0
ICD-10 Finland
Localized oedema
3.5
7.4
34
106
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.3
7.4
26
64
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
7.4
55
234
F84.5
ICD-10 Finland
Asperger syndrome
11.2
7.4
13
12
N06AX17
ATC
milnacipran; oral
9.7
7.4
14
15
A04
ICPC
Weakness/tiredness general
2.5
7.4
60
268
R03BA01
ATC
beclometasone; inhalant
2.6
7.3
53
224
J02AC01
ATC
fluconazole; systemic
1.9
7.3
174
1234
N05BA04
ATC
oxazepam; oral
2.2
7.3
89
487
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
7.3
7
*
Q79.9
ICD-10 Finland
Congenital malformation of musculoskeletal system, unspecified
+∞
7.3
7
*
N03AG01
ATC
valproic acid; systemic, rectal
3.6
7.3
32
96
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
7.3
29
80
J01DB01
ATC
cefalexin; oral
2.4
7.3
272
2303
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
5.5
7.2
20
38
J45.8
ICD-10 Finland
Mixed asthma
5.9
7.2
19
34
7183F
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, POLVI]
30.8
7.2
9
*
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
30.8
7.2
9
*
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
20.6
7.2
10
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
7.1
73
369
J20
ICD-10 Finland
Acute bronchitis
3.1
7.1
40
143
R13
ICD-10 Finland
Dysphagia
4.5
7.1
24
57
L19
ICPC
Muscle symptom/complaint NOS
7.3
7.1
16
23
ZXA10
NOMESCO Finland
Bilateral
2.4
7.1
62
291
R07.3
ICD-10 Finland
Other chest pain
3.3
7.1
34
110
F34.1
ICD-10 Finland
Dysthymia
4.1
7.1
26
67
SPAT1240
SPAT
Therapeutic discussion
2.4
7.1
63
295
S18
ICPC
Laceration/cut
2.0
7.0
111
674
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.6
7.0
17
27
XG466
NOMESCO Finland
Sleep oxymetry
6.6
7.0
17
27
J01MA12
ATC
levofloxacin; systemic
2.6
7.0
53
227
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
5.0
7.0
21
44
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
7.8
7.0
15
20
A06AD11
ATC
lactulose; oral
3.4
7.0
32
100
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
14.2
6.9
11
8
XF402
NOMESCO Finland
ECG with work load test
3.8
6.9
28
79
SPAT1284
SPAT
Extensive health certificate
5.5
6.9
19
36
H02AB09
ATC
hydrocortisone; systemic
5.9
6.9
18
32
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
6.9
43
166
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
11.3
6.9
12
11
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
11.3
6.9
12
11
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
9.6
6.8
13
14
WZA90
NOMESCO Finland
Other doctors statement
2.1
6.8
89
498
M01AX05
ATC
glucosamine; oral
3.3
6.8
34
113
E0000UV
ATC
NA
1.9
6.8
142
954
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.7
6.8
28
80
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.4
6.8
32
102
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
5.1
6.8
20
41
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
7.4
6.8
15
21
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.8
68
338
J05AB11
ATC
valaciclovir; oral
2.6
6.8
50
214
N30.0
ICD-10 Finland
Acute cystitis
2.4
6.8
60
283
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.1
6.8
25
65
M43.1
ICD-10 Finland
Spondylolisthesis
5.4
6.7
19
37
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
6.7
6.7
16
25
R33
ICD-10 Finland
Retention of urine
5.7
6.7
18
33
G72.9
ICD-10 Finland
Myopathy, unspecified
23.1
6.7
9
*
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
23.1
6.7
9
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.1
6.7
17
29
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
6.7
33
109
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
8.1
6.7
14
18
G43.8
ICD-10 Finland
Other migraine
8.1
6.7
14
18
G04CA02
ATC
tamsulosin; oral
4.6
6.7
22
51
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
6.7
48
200
JAH01
NOMESCO Finland
Laparoscopy
3.6
6.7
29
87
TKC20
NOMESCO Finland
Catheterisation of bladder
4.2
6.6
24
61
H03AA01
ATC
levothyroxine sodium; systemic
2.1
6.6
86
480
W19
ICD-10 Finland
Unspecified fall
3.3
6.6
32
104
ZXE00
NOMESCO Finland
One hour or less
1.9
6.6
142
961
N06AB04
ATC
citalopram; systemic
2.1
6.6
79
427
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.7
6.6
21
47
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
6.6
112
694
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
10.3
6.6
12
12
N06AX22
ATC
agomelatine; oral
4.5
6.6
22
52
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.8
6.6
42
165
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.3
6.5
23
57
G47.9
ICD-10 Finland
Sleep disorder, unspecified
5.9
6.5
17
30
XCK00
NOMESCO Finland
Perimetry
4.1
6.5
24
62
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.9
6.5
39
147
L20
ICPC
Joint symptom/complaint NOS
4.6
6.5
21
48
J31.0
ICD-10 Finland
Chronic rhinitis
3.0
6.5
37
135
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.0
6.5
37
135
R03BA08
ATC
ciclesonide; inhalant
2.9
6.5
38
142
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
71.2
6.4
7
*
R4190
NOMESCO Finland
Nutritional therapy
4.2
6.4
23
58
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
6.4
104
635
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
6.4
186
1388
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
6.4
36
129
N81.1
ICD-10 Finland
Cystocele
4.8
6.4
20
44
R05
ICD-10 Finland
Cough
2.3
6.4
62
305
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
6.4
64
320
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
4.5
6.4
21
49
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.5
6.4
28
85
NBE35
NOMESCO Finland
Transposition of ligament of shoulder, arthroscopic
11.3
6.3
11
10
M47.9
ICD-10 Finland
Spondylosis, unspecified
11.3
6.3
11
10
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
11.3
6.3
11
10
9243
FHL
Plastic of the patella and its tendons
11.3
6.3
11
10
C03DA01
ATC
spironolactone; oral
4.0
6.3
24
64
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
6.3
181
1340
L16
ICPC
Ankle symptom/complaint
2.7
6.3
43
174
TKD00
NOMESCO Finland
Dilatation of urethra
18.5
6.3
9
5
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.2
6.3
18
36
1220
FHL
Arthroscopy
5.2
6.3
18
36
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.7
6.3
20
45
J01AA07
ATC
tetracycline; systemic
2.1
6.3
73
389
WX402
NOMESCO Finland
General anaesthesia
2.2
6.3
65
328
Z82.6
ICD-10 Finland
Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
+∞
6.3
6
*
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
+∞
6.3
6
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
27.3
6.3
8
*
NA3BM
NOMESCO Finland
Lumbar spine MRI examination with 3 Tesla magnet
27.3
6.3
8
*
H02AA02
ATC
fludrocortisone; oral
27.3
6.3
8
*
X58
ICD-10 Finland
Exposure to other specified factors
2.3
6.2
58
277
L03
ICPC
Low back symptom/complaint
2.0
6.2
91
532
L13
ICPC
Hip symptom/complaint
2.7
6.2
42
169
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
6.2
94
558
G56.2
ICD-10 Finland
Lesion of ulnar nerve
5.1
6.2
18
37
SPAT1059
SPAT
Spirometry at the office
4.1
6.1
22
56
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
12.9
6.1
10
8
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
12.9
6.1
10
8
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.4
6.1
28
88
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
6.1
138
944
J01MA02
ATC
ciprofloxacin; systemic
1.9
6.1
107
668
I34.1
ICD-10 Finland
Mitral (valve) prolapse
10.3
6.1
11
11
B99
ICD-10 Finland
Other and unspecified infectious diseases
10.3
6.1
11
11
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
10.3
6.1
11
11
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.7
6.1
25
72
M54.3
ICD-10 Finland
Sciatica
3.7
6.1
25
72
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.4
6.1
51
234
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.1
57
273
SPAT1260
SPAT
Consultation of another employee
2.3
6.1
60
298
N06AX12
ATC
bupropion; oral
2.7
6.1
39
154
K59.1
ICD-10 Finland
Functional diarrhoea
3.8
6.0
24
67
R06AX13
ATC
loratadine; oral
2.1
6.0
73
395
Mortality – FinRegistry
↥Association
Association between endpoint Q17_EHLER_SYNDR and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_EHLER_SYNDR.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_EHLER_SYNDR – Ehlers-Danlos syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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