No definition available.
Congenital malformations of the musculoskeletal system, not elsewhere classified
DOID EFO Endpoint Browser PheWeb
Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
540 |
4. Check minimum number of eventsNone |
540 |
5. Include endpointsNone |
540 |
6. Filter based on genotype QC (FinnGen only) |
540 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q6[5-9]|Q7
- Name in latin
- Malformationes congenitae systematis musculosceletalis non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Congenital malformations of the musculoskeletal system, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3921 | 2562 | 1350 |
| Only index persons | 3291 | 2268 | 1023 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.04 |
| Only index persons | 0.07 | 0.08 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 22.80 | 30.56 | 8.01 |
| Only index persons | 27.31 | 33.04 | 14.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 540 | 453 | 87 |
| Unadjusted period prevalence (%) | 0.14 | 0.15 | 0.04 |
| Median age at first event (years) | 37.60 | 38.29 | 33.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 464
- Matched controls
- 4641
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
2312.7
323.0
313
*
M35.7
ICD-10 Finland
Hypermobility syndrome
54.5
128.4
152
41
Z31.5
ICD-10 Finland
Genetic counselling
10.9
72.1
151
196
R4120
NOMESCO Finland
Occupational therapy
11.6
52.1
102
110
Q79.00
ICD-10 Finland
Congenital anterior diaphragmatic hernia
+∞
51.0
48
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
8.9
47.9
110
157
N02AX02
ATC
tramadol; systemic, rectal
4.0
42.8
245
1005
N03AX16
ATC
pregabalin; oral
4.7
42.5
179
548
L28
ICPC
Limited function/disability (L)
6.7
42.4
120
231
N06AX21
ATC
duloxetine; oral
6.1
41.9
128
272
N03AX12
ATC
gabapentin; oral
5.6
41.8
139
328
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
41.3
39
*
R4110
NOMESCO Finland
Physiotherapy
4.3
39.7
186
624
M25.5
ICD-10 Finland
Pain in joint
3.7
35.4
211
855
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.8
31.7
120
316
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
5.4
30.9
101
226
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
8.8
30.5
68
89
M79.7
ICD-10 Finland
Fibromyalgia
9.1
27.3
59
73
SPAT1229
SPAT
Assessment of need for aid
7.3
27.1
68
107
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
5.8
26.7
81
164
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.2
26.4
88
199
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
24.8
155
615
L99
ICPC
Musculoskeletal disease other
14.3
24.7
42
32
A02BC05
ATC
esomeprazole; systemic
2.9
24.3
217
1089
M79.0
ICD-10 Finland
Rheumatism, unspecified
8.2
24.0
55
75
R03AC02
ATC
salbutamol; inhalant
2.8
24.0
311
1954
K07.60
ICD-10 Finland
Snapping jaw
5.3
23.9
77
167
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
23.8
200
964
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.8
23.4
112
358
N02AA05
ATC
oxycodone; systemic
5.0
23.3
80
186
A28
ICPC
Limited function/disability NOS
5.4
23.2
74
158
Q79.9
ICD-10 Finland
Congenital malformation of musculoskeletal system, unspecified
+∞
23.1
22
*
XF404
NOMESCO Finland
Ambulatory ECG
5.8
22.8
68
134
M79.1
ICD-10 Finland
Myalgia
3.7
22.5
111
363
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
3.2
22.2
140
552
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
21.9
232
1269
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
16.4
21.9
35
23
R51.80
ICD-10 Finland
Headache
3.3
21.9
131
497
M03BX01
ATC
baclofen; systemic
14.3
21.9
37
28
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.6
21.7
111
373
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
14.9
21.7
36
26
M79.6
ICD-10 Finland
Pain in limb
2.7
21.2
202
1033
G93.3
ICD-10 Finland
Postviral fatigue syndrome
31.7
20.8
27
9
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
6.7
20.7
54
89
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.5
20.7
78
199
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
20.6
137
555
N06AX16
ATC
venlafaxine; oral
3.4
20.4
114
408
A01
ICPC
Pain general/multiple sites
5.2
19.8
64
138
A03FA01
ATC
metoclopramide; systemic, rectal
3.1
19.6
125
489
R52.2
ICD-10 Finland
Other chronic pain
7.2
19.2
47
71
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.4
19.2
103
356
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
4.0
19.0
82
237
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.8
18.7
153
701
J45.9
ICD-10 Finland
Asthma, unspecified
3.0
18.7
124
497
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
18.6
235
1374
R06.0
ICD-10 Finland
Dyspnoea
2.9
18.3
132
560
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.2
18.2
58
123
N06AA09
ATC
amitriptyline; systemic
4.4
18.0
69
178
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
17.9
140
623
Q79.2
ICD-10 Finland
Exomphalos
+∞
17.8
17
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
6.0
17.5
49
89
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
17.5
157
754
C07AB07
ATC
bisoprolol; oral
2.6
17.5
167
832
M54.5
ICD-10 Finland
Low back pain
2.4
17.4
195
1060
WX002
NOMESCO Finland
Sedation and analgesia
3.1
17.2
106
402
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.4
17.1
64
161
A02BC02
ATC
pantoprazole; systemic
2.3
16.9
288
1917
Q79.3
ICD-10 Finland
Gastroschisis
+∞
16.8
16
*
C07AA05
ATC
propranolol; systemic
2.7
16.8
138
629
C01CA24
ATC
epinephrine; parenteral
3.8
16.5
75
225
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.9
16.5
47
87
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
15.0
16.5
27
19
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.6
16.3
48
93
G44.0
ICD-10 Finland
Cluster headache syndrome
21.9
16.1
23
11
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
16.1
111
452
N02BE01
ATC
paracetamol; systemic, rectal
2.8
16.1
398
3165
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.4
16.0
60
151
Q79.01
ICD-10 Finland
Congenital posteriolateral diaphragmatic hernia
+∞
15.7
15
*
H02AB07
ATC
prednisone; oral
3.3
15.5
85
295
M54.4
ICD-10 Finland
Lumbago with sciatica
2.9
15.5
105
422
G43.9
ICD-10 Finland
Migraine, unspecified
3.7
15.4
71
216
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
15.4
228
1397
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.0
15.3
50
109
R53
ICD-10 Finland
Malaise and fatigue
2.7
15.3
123
549
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.6
15.3
54
128
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.2
15.1
84
296
N04BC09
ATC
rotigotine; transdermal
82.8
14.7
16
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.7
14.6
67
203
A02BA02
ATC
ranitidine; systemic
2.9
14.5
96
379
Z50.1
ICD-10 Finland
Other physical therapy
5.8
14.4
41
76
H02AB06
ATC
prednisolone; systemic
2.2
14.4
222
1368
L29
ICPC
Musculoskeletal sympt/complt other
4.2
14.4
57
151
G47.3
ICD-10 Finland
Sleep apnoea
2.9
14.4
95
374
M01AH01
ATC
celecoxib; oral (coxibs)
3.1
14.3
88
330
SPAT1215
SPAT
Assessment of need for medical rehabilitation
5.7
14.3
41
77
G44.2
ICD-10 Finland
Tension-type headache
2.9
14.3
99
403
J01FF01
ATC
clindamycin; systemic
2.5
14.1
135
661
N05AH04
ATC
quetiapine; oral
2.6
14.1
114
508
N03AE01
ATC
clonazepam; systemic
5.1
14.1
45
96
ZXA05
NOMESCO Finland
Left side
2.7
14.0
113
502
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.8
14.0
102
426
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.2
13.9
187
1080
UKC02
NOMESCO Finland
Cystoscopy
3.6
13.8
64
195
UJF32
NOMESCO Finland
Coloscopy
2.6
13.8
112
500
Q79.10
ICD-10 Finland
Eventration of diaphragm
+∞
13.6
13
*
R51.81
ICD-10 Finland
Facial pain NOS
8.5
13.5
29
36
R5140
NOMESCO Finland
Monitoring the use of the aid
4.2
13.2
51
132
N03AX09
ATC
lamotrigine; oral
4.2
13.1
51
133
SPAT1216
SPAT
Assessment of functional ability
3.3
13.0
68
228
M24.2
ICD-10 Finland
Disorder of ligament
8.9
12.9
27
32
R06AE07
ATC
cetirizine; oral
2.1
12.9
248
1651
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.5
12.9
114
529
R00.2
ICD-10 Finland
Palpitations
3.7
12.9
57
167
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.5
12.7
45
107
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
12.7
111
513
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.2
12.7
49
127
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.2
12.7
70
243
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
5.0
12.7
41
89
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
12.6
167
949
XA800
NOMESCO Finland
Neuropsychological investigation
4.8
12.6
42
94
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
5.5
12.6
37
72
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.4
12.5
64
211
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
12.4
60
189
SPAT1231
SPAT
Assessment of adjustments needed in living environment
16.4
12.2
19
12
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
12.1
86
350
XA402
NOMESCO Finland
ENMG
7.1
12.1
29
43
N03AX11
ATC
topiramate; oral
5.7
12.0
34
63
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
12.0
64
217
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
12.0
177
1048
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.9
12.0
33
59
SBB10
NOMESCO Finland
Teeth copy
3.1
11.9
71
259
M22.0
ICD-10 Finland
Recurrent dislocation of patella
8.7
11.9
25
30
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
10.0
11.9
23
24
A06AC01
ATC
ispaghula (psylla seeds); oral
2.4
11.8
113
547
R5599
NOMESCO Finland
Other rehabilitation service
7.5
11.7
27
38
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
9.0
11.7
24
28
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
11.6
102
472
G54.0
ICD-10 Finland
Brachial plexus disorders
5.8
11.6
32
58
Q76.9
ICD-10 Finland
Congenital malformation of bony thorax, unspecified
+∞
11.5
11
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.4
11.5
56
178
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
11.4
45
119
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.8
11.4
79
318
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
5.2
11.4
35
72
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.0
11.4
69
256
M03BC01
ATC
orphenadrine (citrate); systemic
2.2
11.3
138
746
J01AA02
ATC
doxycycline; systemic
2.1
11.3
339
2632
A02BC03
ATC
lansoprazole; oral
2.3
11.3
125
646
WX402
NOMESCO Finland
General anaesthesia
2.4
11.3
105
500
M89.0
ICD-10 Finland
Algoneurodystrophy
13.1
11.2
19
15
A04
ICPC
Weakness/tiredness general
2.7
11.0
83
351
ZX120
NOMESCO Finland
Intravenous
3.4
11.0
54
173
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
10.9
73
287
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
10.9
96
444
J45
ICD-10 Finland
Asthma
2.9
10.9
69
261
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.1
10.9
63
227
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
10.9
10.9
20
19
J01EA01
ATC
trimethoprim; systemic
2.1
10.8
142
792
Z71.8
ICD-10 Finland
Other specified counselling
2.1
10.8
147
833
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
10.7
59
203
R03BA02
ATC
budesonide; inhalant
2.3
10.7
106
521
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
6.1
10.6
28
48
P01AB01
ATC
metronidazole; oral, rectal
2.0
10.6
202
1310
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
10.5
53
173
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
10.5
98
467
C08DA01
ATC
verapamil; systemic
5.6
10.5
30
57
N05CF01
ATC
zopiclone; oral
2.2
10.5
129
698
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.4
10.4
24
34
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
10.4
104
513
XKD00
NOMESCO Finland
Uroflowmetry
3.6
10.4
47
141
J01FA06
ATC
roxithromycin; oral
2.0
10.4
194
1246
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.7
10.3
71
286
M54.2
ICD-10 Finland
Cervicalgia
3.3
10.3
52
170
ZXA10
NOMESCO Finland
Bilateral
2.4
10.3
90
415
M54.6
ICD-10 Finland
Pain in thoracic spine
3.2
10.3
54
182
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.0
10.3
189
1205
R02
ICPC
Shortness of breath/dyspnoea
2.8
10.2
69
271
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
10.2
179
1121
R20.2
ICD-10 Finland
Paraesthesia of skin
3.3
10.2
51
166
N06AX11
ATC
mirtazapine; oral
2.0
10.2
152
893
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
10.1
53
178
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.8
10.1
69
275
U07
ICPC
Urine symptom/complaint other
4.4
10.1
36
87
N04BC05
ATC
pramipexole; oral
3.9
10.1
41
112
N02CC03
ATC
zolmitriptan; nasal, oral
3.4
10.1
50
161
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.4
10.1
50
161
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
10.1
56
194
G43.3
ICD-10 Finland
Complicated migraine
7.0
10.0
24
36
T78.4
ICD-10 Finland
Allergy, unspecified
3.5
10.0
47
145
AA1AD
NOMESCO Finland
CT of head and brain
2.5
10.0
83
371
R51
ICD-10 Finland
Headache
3.6
9.9
45
135
J01FA10
ATC
azithromycin; systemic
1.9
9.9
318
2463
R1250
NOMESCO Finland
Evaluation of functional capability
7.3
9.9
23
33
J01DB01
ATC
cefalexin; oral
2.2
9.9
387
3240
M03BC51
ATC
orphenadrine, combinations; systemic
2.1
9.9
139
795
N05BA01
ATC
diazepam; systemic, rectal
2.7
9.8
70
285
N06AB06
ATC
sertraline; oral
2.6
9.8
77
335
M01AH02
ATC
rofecoxib; oral
3.0
9.7
57
207
M03BX02
ATC
tizanidine; oral
1.9
9.7
290
2179
M22.4
ICD-10 Finland
Chondromalacia patellae
4.4
9.7
34
81
M47.82
ICD-10 Finland
Other spondylosis, cervical region
5.5
9.7
28
54
R42
ICD-10 Finland
Dizziness and giddiness
2.3
9.7
99
489
J98.6
ICD-10 Finland
Disorders of diaphragm
56.2
9.7
11
*
N06AB04
ATC
citalopram; systemic
2.2
9.6
109
568
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
10.4
9.6
18
18
R06AX22
ATC
ebastine; oral
2.3
9.6
101
509
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.4
9.6
15
10
R11
ICD-10 Finland
Nausea and vomiting
3.0
9.6
55
197
WX110
NOMESCO Finland
Local anesthesy
2.0
9.5
347
2794
R50.9
ICD-10 Finland
Fever, unspecified
2.4
9.5
83
382
R03DC03
ATC
montelukast; oral
2.2
9.5
106
548
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
9.4
168
1050
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
12.7
9.4
16
13
J01MA12
ATC
levofloxacin; systemic
2.5
9.4
76
332
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
5.4
9.4
27
52
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
11.0
9.4
17
16
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
11.0
9.4
17
16
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
9.3
70
295
Z01.9
ICD-10 Finland
Special examination, unspecified
4.2
9.3
34
85
R03BA05
ATC
fluticasone; inhalant
2.2
9.2
110
582
R52.1
ICD-10 Finland
Chronic intractable pain
14.0
9.2
15
11
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
14.0
9.2
15
11
R06AX27
ATC
desloratadine; oral
1.9
9.2
176
1127
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
9.2
223
1552
M25.2
ICD-10 Finland
Flail joint
7.3
9.1
21
30
M02AA07
ATC
piroxicam; topical
2.0
9.1
143
847
N02CC05
ATC
almotriptan; oral
3.4
9.1
43
134
M01AH05
ATC
etoricoxib; oral
1.8
9.1
260
1906
R4190
NOMESCO Finland
Nutritional therapy
3.6
9.1
40
118
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
9.0
103
534
D07AD01
ATC
clobetasol; topical
2.5
9.0
74
325
ZXA00
NOMESCO Finland
Right side
2.2
9.0
103
537
B02AA02
ATC
tranexamic acid; systemic
2.2
9.0
97
492
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.9
9.0
56
212
A02BC01
ATC
omeprazole; systemic
2.1
9.0
124
698
G50.1
ICD-10 Finland
Atypical facial pain
8.2
8.9
19
24
XQ800
NOMESCO Finland
Prick test
2.7
8.9
65
268
M22.1
ICD-10 Finland
Recurrent subluxation of patella
12.9
8.9
15
12
M01AC06
ATC
meloxicam; systemic, rectal
2.0
8.9
148
898
L20
ICPC
Joint symptom/complaint NOS
5.3
8.9
26
51
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
8.9
161
1008
R13
ICD-10 Finland
Dysphagia
4.0
8.8
34
89
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
8.8
70
303
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.2
8.8
26
52
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
5.7
8.7
24
44
L03
ICPC
Low back symptom/complaint
2.0
8.7
124
708
N06AX17
ATC
milnacipran; oral
11.9
8.6
15
13
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
8.6
72
322
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
16.7
8.6
13
8
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.8
8.6
55
212
N06AX22
ATC
agomelatine; oral
5.6
8.6
24
45
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
7.6
8.5
19
26
N02CC07
ATC
frovatriptan; oral
3.6
8.5
37
108
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
8.5
121
690
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
8.5
50
183
A04AA01
ATC
ondansetron; systemic, rectal
3.4
8.5
40
125
N03AG01
ATC
valproic acid; systemic, rectal
3.4
8.5
40
125
F50.9
ICD-10 Finland
Eating disorder, unspecified
6.4
8.4
21
34
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
8.4
53
202
J02AC01
ATC
fluconazole; systemic
1.8
8.4
224
1588
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.5
8.4
38
115
A03FA02
ATC
cisapride; oral, rectal
3.5
8.3
38
116
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
6.7
8.3
20
31
R06AE09
ATC
levocetirizine; oral
2.2
8.3
92
471
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.3
8.2
40
128
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.5
8.2
69
308
N30.0
ICD-10 Finland
Acute cystitis
2.3
8.2
79
380
N81.6
ICD-10 Finland
Rectocele
3.4
8.2
39
123
J01MA02
ATC
ciprofloxacin; systemic
1.9
8.2
151
946
R33
ICD-10 Finland
Retention of urine
5.2
8.1
24
48
G81.9
ICD-10 Finland
Hemiplegia, unspecified
12.0
8.1
14
12
J20
ICD-10 Finland
Acute bronchitis
2.8
8.1
54
212
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
8.1
264
1987
L02
ICPC
Back symptom/complaint
2.6
8.1
61
259
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
8.1
140
858
G43
ICD-10 Finland
Migraine
3.1
8.0
45
157
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
8.0
57
233
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.0
8.0
121
705
JAH01
NOMESCO Finland
Laparoscopy
3.6
8.0
35
103
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
8.0
46
166
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
8.0
46
166
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.6
7.9
22
41
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
13.3
7.9
13
10
F45.8
ICD-10 Finland
Other somatoform disorders
2.5
7.9
62
268
M01AE02
ATC
naproxen; oral, rectal
1.7
7.9
283
2190
TKC20
NOMESCO Finland
Catheterisation of bladder
4.0
7.8
30
79
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.6
7.8
19
30
R4130
NOMESCO Finland
Speech therapy
6.6
7.8
19
30
R5110
SPAT
NA
6.6
7.8
19
30
N06BA12
ATC
lisdexamfetamine; oral
15.4
7.7
12
8
X58
ICD-10 Finland
Exposure to other specified factors
2.3
7.7
78
380
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.5
7.7
35
106
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
7.7
46
170
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
7.7
338
2769
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
10.3
7.6
14
14
K59.09
ICD-10 Finland
Constipation, unspecified
3.7
7.6
32
92
S43.0
ICD-10 Finland
Dislocation of shoulder joint
4.4
7.5
26
62
R52.9
ICD-10 Finland
Pain, unspecified
2.7
7.5
52
210
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
5.2
7.5
22
44
M50.3
ICD-10 Finland
Other cervical disc degeneration
6.6
7.5
18
28
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.4
7.5
65
297
F48.0
ICD-10 Finland
Neurasthenia
81.3
7.4
8
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
7.4
70
333
F34.1
ICD-10 Finland
Dysthymia
3.9
7.4
29
78
N05CD07
ATC
temazepam; oral
2.9
7.4
44
163
JG1JB
NOMESCO Finland
Defekography with X-ray
11.1
7.3
13
12
J45.8
ICD-10 Finland
Mixed asthma
4.4
7.3
25
59
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
9.6
7.3
14
15
A02BA03
ATC
famotidine; systemic
5.6
7.3
20
37
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
5.6
7.3
20
37
M54.8
ICD-10 Finland
Other dorsalgia
4.1
7.3
27
69
3007
Kela drug reimbursment
Erenumab and fremanezumab
6.0
7.3
19
33
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.5
7.3
32
95
N06AB10
ATC
escitalopram; oral
1.9
7.3
120
717
XF402
NOMESCO Finland
ECG with work load test
3.1
7.2
39
135
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.8
7.2
155
1012
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
30.5
7.2
9
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.5
7.1
24
56
PD5BD
NOMESCO Finland
Extensive CT of aorta
12.3
7.1
12
10
R1260
NOMESCO Finland
Evaluation of communicative skills
12.3
7.1
12
10
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.1
7.1
38
131
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
9.0
7.1
14
16
R03BB04
ATC
tiotropium bromide; inhalant
3.2
7.1
35
114
S06.0
ICD-10 Finland
Concussion
2.5
7.1
55
237
R03AC03
ATC
terbutaline; inhalant
2.1
7.1
80
411
M53.2
ICD-10 Finland
Spinal instabilities
10.2
7.1
13
13
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
4.4
7.0
24
57
XG466
NOMESCO Finland
Sleep oxymetry
5.3
7.0
20
39
C03CA01
ATC
furosemide; systemic
2.3
7.0
65
307
N03AF01
ATC
carbamazepine; oral, rectal
3.8
7.0
28
77
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
6.5
7.0
17
27
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.7
7.0
259
1988
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.7
7.0
261
2007
N02CC04
ATC
rizatriptan; oral
2.6
6.9
48
194
RK110
NOMESCO Finland
NA
14.0
6.9
11
8
A06AC51
ATC
ispaghula, combinations; systemic
3.5
6.9
31
94
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
6.9
64
302
F60.9
ICD-10 Finland
Personality disorder, unspecified
6.9
6.9
16
24
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
6.9
54
235
A06AD11
ATC
lactulose; oral
2.6
6.8
50
207
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.9
6.8
40
146
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
6.8
97
547
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
9.5
6.8
13
14
F84.5
ICD-10 Finland
Asperger syndrome
9.5
6.8
13
14
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.2
6.8
72
358
R03BA08
ATC
ciclesonide; inhalant
2.6
6.8
50
208
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
40.7
6.8
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
6.7
74
377
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.4
6.7
31
96
H02AB09
ATC
hydrocortisone; systemic
4.3
6.7
23
55
M70.6
ICD-10 Finland
Trochanteric bursitis
2.6
6.7
47
192
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
22.9
6.7
9
*
L13
ICPC
Hip symptom/complaint
2.3
6.7
60
278
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.7
6.7
21
46
J01DA01
ATC
[U] cefalexin; systemic
1.7
6.7
278
2193
SPAT1059
SPAT
Spirometry at the office
3.5
6.7
29
86
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.5
6.6
22
51
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
12.5
6.6
11
9
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
6.6
27
76
N80.9
ICD-10 Finland
Endometriosis, unspecified
4.1
6.6
24
61
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
6.6
236
1782
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
6.6
66
321
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.2
6.6
19
38
L12
ICPC
Hand/finger symptom/complaint
2.0
6.6
86
470
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.4
6.5
30
93
R15
ICD-10 Finland
Faecal incontinence
5.8
6.5
17
30
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.8
6.5
26
72
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.0
6.5
35
122
D01
ICPC
Abdominal pain/cramps general
2.2
6.5
70
353
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
6.5
74
382
R06AX26
ATC
fexofenadine; oral
2.6
6.4
45
183
S73.0
ICD-10 Finland
Dislocation of hip
70.8
6.4
7
*
J01FA09
ATC
clarithromycin; systemic
1.7
6.4
155
1044
M23.5
ICD-10 Finland
Chronic instability of knee
14.6
6.4
10
7
R03AC13
ATC
formoterol; inhalant
3.8
6.4
25
68
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
6.4
259
2018
SPAT1097
SPAT
Recording of ECG
2.4
6.4
51
224
I34.1
ICD-10 Finland
Mitral (valve) prolapse
8.3
6.4
13
16
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
6.4
65
320
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
6.4
41
159
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
6.4
58
271
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
6.3
29
90
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.7
6.3
26
74
7183F
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, POLVI]
18.3
6.3
9
5
TQW40
NOMESCO Finland
Remowal of suture of skin
3.0
6.3
34
119
JBB10
NOMESCO Finland
Repair of congenital diaphragmatic hernia
+∞
6.3
6
*
Q79.5
ICD-10 Finland
Other congenital malformations of abdominal wall
+∞
6.3
6
*
Q79.18
ICD-10 Finland
Other congenital malformations of diaphragm
+∞
6.3
6
*
L82
ICPC
Congenital anomaly musculoskeletal
+∞
6.3
6
*
JAG20
NOMESCO Finland
Repair of omphalocele
+∞
6.3
6
*
JAG10
NOMESCO Finland
Repair of gastroschisis
+∞
6.3
6
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.9
6.3
36
130
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.1
6.2
32
108
C09CA06
ATC
candesartan; oral
2.0
6.2
89
502
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
6.2
115
712
R07.3
ICD-10 Finland
Other chest pain
2.6
6.2
43
173
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
5.9
6.2
16
28
S83.0
ICD-10 Finland
Dislocation of patella
4.0
6.2
23
60
N05CF02
ATC
zolpidem; oral
2.0
6.2
85
473
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.8
6.2
19
41
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.8
6.1
37
139
J01MA14
ATC
moxifloxacin; systemic
2.8
6.1
37
139
L17
ICPC
Foot/toe symptom/complaint
1.8
6.1
114
705
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
5.0
6.1
18
37
EB1WA
NOMESCO Finland
NA
12.7
6.1
10
8
K07.61
ICD-10 Finland
Cracking jaw joint
4.3
6.1
21
51
R52.0
ICD-10 Finland
Acute pain
3.8
6.1
24
66
JAF10
NOMESCO Finland
Repair of umbilical hernia
6.8
6.1
14
21
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
6.1
23
61
N02CC02
ATC
naratriptan; oral
5.3
6.1
17
33
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
10.2
6.1
11
11
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
5.7
6.0
16
29
N02CD01
ATC
erenumab; parenteral
6.2
6.0
15
25
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.5
6.0
26
77
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
14
19.46
32.80
1.7
3.0
123.4
114.4
%
0.20
26
14
324
1851
2.88
31.32
8.4
6.1
1.2
1.2
mmol/l
2.37
279
1592
289
1651
2.61
26.43
8.5
5.7
1.2
1.2
mmol/l
3.14
268
1527
122
447
3.23
25.99
2.2
2.1
340.0
373.7
nmol/l
1.16
106
424
309
1841
2.59
25.60
3.5
2.3
76.5
73.6
nmol/l
1.07
286
1710
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
25
21
12.43
24.89
1.2
1.0
121.2
138.0
%
0.72
25
21
137
550
3.00
24.83
4.0
3.6
0.8
0.8
mmol/l
1.15
123
518
249
1359
2.54
24.57
4.7
2.9
—
—
—
0
0
252
1390
2.52
24.23
2.5
1.7
99.5
97.0
pmol/l
0.36
146
745
25
22
11.87
24.17
1.1
1.0
106.3
100.0
%
0.54
11
15
435
3128
3.01
23.65
8.4
6.3
76.3
76.9
u/l
0.08
414
2951
211
1083
2.56
23.50
4.6
2.7
0.1
0.3
e6/l
4.52
170
778
349
2274
2.51
22.83
6.0
4.3
6.0
6.3
mmol/l
2.69
335
2051
23
21
11.40
21.68
1.1
1.0
97.4
106.8
%
—
9
14
56
138
4.41
21.16
6.5
4.7
3.0
3.4
g/l
1.65
51
133
382
2648
2.51
20.99
9.2
8.5
4.1
3.9
e9/l
0.81
347
2302
196
1020
2.45
20.69
2.2
2.0
148.6
210.8
u/l
0.41
188
969
402
2893
2.52
19.68
5.8
3.9
611.3
664.2
e6/l
—
6
38
136
609
2.65
19.59
4.2
2.5
4.9
3.6
e6/l
0.45
73
304
310
2003
2.29
19.38
5.8
5.5
10.3
10.6
umol/l
0.14
296
1884
127
558
2.67
18.95
3.1
2.3
14.7
14.4
umol/l
0.19
118
515
139
639
2.58
18.91
4.0
2.4
0.9
0.9
e6/l
0.00
77
333
68
211
3.54
18.60
1.3
1.3
0.2
0.9
u/ml
—
7
13
108
444
2.79
18.29
3.1
2.4
23.9
23.9
%
0.01
95
381
245
1473
2.21
17.83
3.7
3.0
33.8
27.9
u/l
0.39
239
1418
250
1516
2.21
17.80
5.4
4.3
36.1
36.8
g/l
1.17
238
1432
113
498
2.60
16.58
3.1
2.2
2.5
2.4
g/l
0.14
103
459
427
3266
2.47
16.53
5.0
3.8
9.3
9.3
mm/h
0.02
403
3070
79
292
3.00
16.17
6.1
7.4
1.0
1.1
mmol/l
0.10
59
231
91
375
2.72
15.19
1.4
1.3
193.3
253.8
u/ml
0.26
83
348
183
1057
2.11
14.03
3.6
2.1
2.5
2.8
mg/l
1.49
155
913
135
695
2.26
13.82
2.4
3.1
934.5
777.6
ng/l
0.16
108
564
201
1210
2.05
13.73
3.5
2.4
51.9
54.4
u/l
0.52
188
1134
314
2230
1.98
13.19
4.3
3.2
0.0
0.0
estimate
0.00
70
446
17
6
29.18
13.03
1.1
1.8
—
—
—
0
0
311
2209
1.96
12.98
6.1
4.4
0.0
0.0
estimate
0.50
68
460
310
2200
1.96
12.96
4.2
3.1
0.0
0.0
estimate
0.00
69
441
171
993
2.06
12.72
2.9
2.1
1.4
0.7
mg/l
0.69
126
737
207
1290
1.98
12.60
3.0
3.0
2.3
2.4
mmol/l
0.84
189
1171
76
315
2.64
12.45
4.5
2.7
0.2
0.2
g/l
0.62
70
299
143
791
2.10
12.03
1.7
1.4
20.6
21.4
nmol/l
0.23
127
692
17
23
7.60
11.90
3.5
2.5
374.4
635.6
u/ml
1.09
17
23
193
1207
1.93
11.40
3.5
2.9
17.3
24.0
ng/l
0.85
88
595
329
2454
1.87
11.07
4.3
2.9
61.9
70.4
ug/l
1.28
308
2323
150
869
2.01
11.00
1.5
1.3
41.5
28.1
iu/ml
0.29
38
274
38
114
3.51
10.89
1.5
1.4
331.5
316.1
ug/g
0.14
17
64
43
141
3.23
10.72
8.4
10.0
24.2
24.3
mmol/l
0.05
43
135
103
524
2.19
10.63
2.1
1.6
1058.6
1148.6
nmol/l
0.38
81
412
57
221
2.77
10.60
1.8
1.6
—
—
—
0
0
80
368
2.38
10.46
2.9
2.5
32.7
32.5
u/l
0.02
69
310
127
709
2.03
10.25
1.6
1.5
140566512.7
23697118.2
pmol/l
0.39
106
633
515
4607
3.55
9.81
19.5
10.4
19.0
19.4
mg/l
0.10
433
3480
161
989
1.89
9.78
2.9
2.0
—
—
—
0
0
112
609
2.06
9.67
2.5
2.8
795.7
247.6
ng/l
0.74
62
341
72
332
2.35
9.34
10.4
5.5
1.6
1.7
mmol/l
0.09
60
246
45
167
2.85
9.08
8.7
9.2
0.6
0.7
%
0.29
45
167
444
3760
2.02
8.93
5.2
4.2
14.4
14.4
pmol/l
0.08
416
3527
141
856
1.88
8.76
1.4
1.3
10.9
11.3
u/ml
0.02
53
342
43
159
2.85
8.73
10.1
5.1
9.0
9.0
kpa
0.01
43
148
281
2089
1.72
8.69
4.6
3.9
—
—
—
0
0
38
132
3.02
8.62
1.4
1.8
—
253.3
—
0
6
44
167
2.78
8.52
9.0
9.2
1.1
1.4
%
1.04
44
167
74
362
2.21
8.34
2.5
2.2
20.6
20.6
au/ml
—
8
22
43
164
2.76
8.25
9.1
9.4
94.5
94.3
%
0.09
43
164
87
459
2.07
8.07
4.1
3.1
5.4
5.8
umol/l
0.19
75
386
70
343
2.20
7.85
3.5
2.9
—
—
—
0
0
59
270
2.33
7.77
8.8
4.7
1.6
1.3
mmol/l
0.31
50
193
48
202
2.51
7.59
2.0
1.9
—
—
—
0
0
62
293
2.26
7.58
11.5
13.5
1.0
1.2
inr
—
8
53
17
37
4.71
7.45
1.2
2.9
—
—
—
0
0
59
282
2.23
7.02
8.9
4.5
5.4
5.1
kpa
1.59
59
262
40
162
2.59
6.85
1.6
1.3
—
—
—
0
0
232
1718
1.61
6.73
4.2
3.1
—
—
—
0
0
56
267
2.22
6.71
5.8
4.1
64.9
69.7
ng/l
0.21
50
246
25
79
3.27
6.65
2.0
2.4
134.3
132.8
g/l
0.15
19
58
24
74
3.35
6.63
1.5
1.3
—
—
—
0
0
24
74
3.35
6.63
1.5
1.3
—
—
—
0
0
81
447
1.96
6.59
1.8
1.5
21.4
23.1
iu/l
0.18
65
380
37
147
2.63
6.59
1.3
1.2
—
17.6
—
0
11
35
136
2.68
6.51
1.2
1.2
—
18.1
—
0
28
66
340
2.07
6.50
1.9
1.6
—
—
—
0
0
514
4739
2.76
6.41
12.4
8.5
24.8
24.3
u/l
0.22
504
4619
28
98
2.96
6.30
1.1
1.3
—
1.2
—
0
9
43
188
2.40
6.29
1.9
2.5
90.3
107.1
ng/l
0.21
35
168
67
352
2.03
6.26
4.8
3.6
4.9
4.7
pmol/l
0.30
58
313
146
978
1.68
6.22
3.6
3.1
1.0
1.0
kg/l
0.21
20
142
66
346
2.03
6.20
2.0
1.6
—
—
—
0
0
55
274
2.12
5.91
2.6
3.7
1.2
1.2
mmol/l
0.34
43
236
24
80
3.09
5.87
1.2
1.2
—
—
—
0
0
43
195
2.31
5.80
2.0
1.4
—
—
—
0
0
477
4303
1.93
5.75
6.2
4.8
1.6
2.0
mu/l
0.81
460
4088
33
134
2.56
5.65
1.2
1.2
—
3.1
—
0
17
86
513
1.80
5.49
2.1
1.8
—
—
—
0
0
38
169
2.34
5.37
1.8
2.3
—
—
—
0
0
450
4012
1.73
5.33
15.1
8.9
95.4
92.3
ml/min/173m2
2.64
390
3210
79
468
1.81
5.15
1.4
1.3
75.2
167.8
iu/ml
2.87
34
200
454
4068
1.73
5.15
3.8
3.5
5.6
5.6
mmol/l
0.56
417
3811
161
1151
1.57
5.14
4.3
3.4
0.0
0.0
estimate
0.80
70
455
11
23
4.86
5.03
1.1
1.1
—
—
—
0
0
36
163
2.29
4.90
1.3
1.1
—
—
—
0
0
129
902
1.57
4.47
2.3
2.6
300.4
4572.8
umol/l
2.87
117
815
17
55
3.16
4.39
1.8
1.6
—
—
—
0
0
18
61
3.02
4.32
1.9
2.7
17.6
16.5
%
0.71
13
30
22
85
2.66
4.19
1.6
2.2
167.8
173.6
ug/l
0.03
15
76
16
52
3.14
4.11
1.2
1.1
—
—
—
0
0
16
52
3.14
4.11
1.2
1.1
—
—
—
0
0
37
183
2.10
4.09
2.9
2.1
6.1
10.4
nmol/l
2.19
31
169
72
445
1.71
4.06
2.5
2.1
5060.6
3323.4
u/l
0.26
24
181
180
1377
1.46
4.01
1.4
1.4
0.6
1.9
u/ml
2.57
42
356
9
14
6.52
3.99
3.3
2.0
142.6
131.3
ug/l
—
9
14
16
53
3.08
3.99
1.2
1.1
—
—
—
0
0
16
53
3.08
3.99
1.2
1.1
—
—
—
0
0
16
53
3.08
3.99
1.2
1.1
—
—
—
0
0
12
33
3.70
3.94
6.7
7.3
12.0
10.8
mg/l
0.36
12
27
7
9
7.86
3.57
1.1
1.0
—
—
—
0
0
94
646
1.55
3.47
1.6
1.5
1.5
1.3
%
1.14
79
594
22
96
2.35
3.31
1.4
2.0
3.6
3.7
g/l
0.09
17
80
22
96
2.35
3.31
1.4
2.0
—
—
—
0
0
13
43
3.07
3.27
1.4
1.1
—
—
—
0
0
55
336
1.71
3.25
2.3
1.7
—
—
—
0
0
17
66
2.63
3.24
1.2
1.4
—
—
—
0
0
88
607
1.54
3.19
2.7
2.4
2.4
2.4
mmol/l
0.15
76
535
13
44
3.00
3.15
1.4
1.1
—
—
—
0
0
53
324
1.70
3.13
1.4
1.6
306.3
316.9
mu/l
0.14
46
297
30
155
1.99
3.01
1.9
1.6
—
—
—
0
0
20
89
2.30
2.90
3.5
3.5
1.9
1.1
mmol/l
1.20
20
89
38
218
1.80
2.80
1.5
1.6
9.5
10.4
u/l
0.15
29
182
85
599
1.50
2.80
2.1
1.7
—
—
—
0
0
25
125
2.05
2.75
1.4
1.3
—
—
—
0
0
353
3154
1.34
2.70
4.1
2.9
33.9
35.7
u/l
0.25
332
3031
19
87
2.23
2.60
2.8
3.1
25.7
24.6
mmol/l
0.87
19
74
13
50
2.64
2.55
1.5
1.6
—
—
—
0
0
403
3695
1.36
2.46
4.5
4.3
36.0
37.8
mmol/mol
5.14
372
3510
47
299
1.63
2.43
3.2
2.1
72.7
77.9
ml/min/173m2
0.30
20
118
37
592
0.60
2.41
1.6
1.5
—
—
—
0
0
18
85
2.16
2.31
1.6
1.3
—
—
—
0
0
7
18
3.92
2.26
1.1
1.1
—
—
—
0
0
5
10
5.03
2.07
1.2
1.2
—
—
—
0
0
26
147
1.81
2.06
1.2
1.2
—
—
—
0
0
23
396
0.56
2.00
1.4
1.4
—
—
—
0
0
22
120
1.87
1.95
1.6
1.4
237.0
177.5
u/ml
0.48
13
72
6
16
3.78
1.94
1.2
2.2
—
—
—
0
0
99
768
1.35
1.93
2.3
1.9
—
—
—
0
0
17
85
2.03
1.92
1.8
2.2
0.9
0.8
nmol/l
0.19
17
74
14
65
2.18
1.89
1.4
1.7
—
—
—
0
0
172
1445
1.28
1.89
1.8
1.7
—
—
—
0
0
9
34
2.67
1.87
1.1
1.2
—
—
—
0
0
18
325
0.54
1.85
1.6
1.4
—
—
—
0
0
25
145
1.76
1.84
1.2
1.2
—
—
—
0
0
17
87
1.99
1.81
3.3
4.1
50.4
56.5
%
1.21
17
87
21
355
0.58
1.73
1.6
1.5
—
—
—
0
0
5
13
3.87
1.72
1.6
2.3
—
—
—
0
0
5
13
3.87
1.72
1.6
2.3
—
—
—
0
0
11
48
2.32
1.71
1.4
1.4
—
—
—
0
0
8
31
2.60
1.66
1.1
1.7
—
—
—
0
0
8
31
2.60
1.66
1.8
1.7
—
—
—
0
0
19
326
0.57
1.66
1.5
1.4
—
—
—
0
0
19
326
0.57
1.66
1.5
1.4
—
—
—
0
0
19
326
0.57
1.66
1.5
1.4
—
—
—
0
0
27
166
1.66
1.65
1.2
1.2
1.5
3.2
u/ml
0.50
16
81
24
143
1.71
1.64
1.5
1.5
0.2
0.4
nmol/l
1.57
19
119
18
98
1.87
1.63
1.2
1.1
—
—
—
0
0
38
550
0.67
1.62
1.6
1.5
—
—
—
0
0
17
91
1.90
1.62
1.4
1.6
—
—
—
0
0
132
1093
1.27
1.61
2.1
2.1
—
—
—
0
0
11
50
2.22
1.58
1.1
1.1
—
—
—
0
0
11
50
2.22
1.58
1.8
1.3
—
—
—
0
0
24
145
1.69
1.57
1.7
1.6
0.1
0.0
iu/ml
—
5
25
16
85
1.91
1.56
3.4
3.6
3.3
4.4
e9/l
2.08
16
85
466
4453
1.34
1.55
21.1
11.2
40.2
39.9
%
0.44
380
3697
11
51
2.18
1.51
1.8
1.3
—
—
—
0
0
11
51
2.18
1.51
1.8
1.3
—
—
—
0
0
11
51
2.18
1.51
1.8
1.3
—
—
—
0
0
11
52
2.14
1.45
1.8
1.3
—
—
—
0
0
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
9
39
2.33
1.43
1.3
1.7
—
—
—
0
0
16
88
1.84
1.43
1.4
1.6
—
—
—
0
0
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
18
106
1.72
1.31
1.2
1.4
94.7
113.1
u/ml
—
7
23
9
43
2.11
1.31
1.0
1.0
—
—
—
0
0
139
1186
1.23
1.30
2.3
2.2
—
—
—
0
0
10
48
2.10
1.28
1.4
1.4
269.8
660.4
pmol/l
—
10
38
9
45
2.02
1.24
1.0
1.0
197.1
190.0
mg/l
—
9
40
5
19
2.65
1.22
1.2
1.5
—
15.2
—
0
6
5
19
2.65
1.22
1.0
1.0
—
—
—
0
0
8
38
2.12
1.19
1.0
1.6
—
—
—
0
0
16
94
1.72
1.18
1.4
1.6
—
—
—
0
0
14
235
0.58
1.17
1.4
1.7
—
—
—
0
0
10
50
2.02
1.17
1.8
1.3
—
—
—
0
0
5
20
2.51
1.15
1.4
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
31
2.27
1.10
1.1
1.2
—
—
—
0
0
10
52
1.94
1.06
1.9
1.3
—
—
—
0
0
22
146
1.53
1.05
1.2
1.3
—
—
—
0
0
11
60
1.85
1.03
2.0
2.1
86.1
4.2
u/ml
0.46
11
51
16
99
1.63
1.01
1.0
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
9
51
1.78
0.95
1.3
1.6
—
—
—
0
0
7
37
1.90
0.94
1.1
1.0
—
—
—
0
0
10
55
1.83
0.92
1.3
1.6
—
—
—
0
0
6
28
2.16
0.91
1.8
1.6
—
—
—
0
0
6
28
2.16
0.91
1.8
1.6
—
—
—
0
0
6
28
2.16
0.91
1.8
1.6
—
—
—
0
0
21
143
1.49
0.91
1.5
1.4
25.9
19.6
u/l
0.42
16
123
19
277
0.67
0.91
1.3
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
12
71
1.71
0.89
5.6
6.2
0.3
0.4
u/ml
—
6
41
8
42
1.92
0.89
1.7
1.6
—
—
—
0
0
17
111
1.55
0.88
1.0
1.1
1.1
2.4
u/ml
—
6
55
138
1223
1.17
0.86
1.5
1.5
—
—
—
0
0
438
4227
1.19
0.85
4.1
3.8
2.9
2.9
mmol/l
0.20
409
4001
13
202
0.63
0.84
1.3
1.5
—
—
—
0
0
10
57
1.77
0.84
1.1
1.1
—
—
—
0
0
8
47
1.71
0.81
1.1
1.7
—
—
—
0
0
48
387
1.26
0.77
6.4
4.9
—
—
—
0
0
10
59
1.71
0.76
1.7
2.2
—
—
—
0
0
10
59
1.71
0.76
1.1
1.1
—
—
—
0
0
5
24
2.09
0.74
1.2
1.2
—
—
—
0
0
14
207
0.67
0.74
2.1
2.0
—
—
—
0
0
7
38
1.85
0.73
1.1
1.1
—
—
—
0
0
5
25
2.01
0.73
2.2
1.6
17.9
31.2
ug/l
—
5
25
7
39
1.81
0.72
1.3
1.6
—
—
—
0
0
13
84
1.56
0.72
1.0
1.1
—
—
—
0
0
26
195
1.35
0.71
3.5
2.7
0.5
0.8
ug/l
1.68
15
110
5
26
1.93
0.71
1.0
1.0
—
—
—
0
0
5
26
1.93
0.71
1.0
1.2
1343.4
1551.6
miu/ml
—
5
26
17
118
1.46
0.70
1.3
2.3
17.4
159.0
e6/l
1.38
12
93
17
118
1.46
0.70
1.3
2.2
1.3
6.8
e6/l
1.35
12
89
433
4197
1.16
0.68
3.8
3.5
4.7
4.8
mmol/l
0.27
412
4003
5
27
1.86
0.68
1.4
2.1
—
—
—
0
0
431
4178
1.16
0.67
3.7
3.5
1.5
1.5
mmol/l
1.86
404
3970
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
21
156
1.36
0.62
1.8
1.9
2.9
6.0
iu/l
—
9
55
5
30
1.67
0.61
1.4
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
2.4
—
—
—
0
0
0
20
0.00
0.60
0.0
2.4
—
—
—
0
0
117
1055
1.14
0.59
1.5
1.7
1.5
1.4
mmol/l
0.52
100
935
24
186
1.30
0.55
1.5
1.3
—
—
—
0
0
15
109
1.39
0.51
1.4
1.8
—
—
—
0
0
14
101
1.40
0.50
1.4
1.3
—
—
—
0
0
7
47
1.50
0.47
1.1
1.2
24.6
35.3
nmol/l
—
7
37
32
267
1.21
0.43
3.1
4.2
2.7
7.4
ug/l
1.67
23
212
5
31
1.62
0.43
1.2
1.1
—
79.0
—
0
6
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
8
60
1.34
0.40
1.0
1.3
—
—
—
0
0
409
3999
1.09
0.37
3.5
3.2
1.3
1.2
mmol/l
1.50
384
3793
9
70
1.29
0.37
1.3
1.2
—
—
—
0
0
6
42
1.43
0.35
1.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.3
—
—
—
0
0
19
157
1.22
0.30
1.7
1.5
—
—
—
0
0
7
56
1.25
0.29
1.1
1.1
—
—
—
0
0
43
384
1.13
0.28
1.1
1.0
—
—
—
0
0
5
72
0.69
0.26
1.8
1.5
—
—
—
0
0
30
263
1.15
0.26
4.5
3.9
23.9
22.6
%
—
9
113
16
132
1.22
0.26
4.5
2.8
7.0
7.3
umol/l
0.04
16
101
385
3916
0.94
0.24
4.1
3.8
—
—
—
0
0
10
124
0.80
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
3.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
0.8
—
0
10
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
7
60
1.17
0.18
1.1
1.1
—
—
—
0
0
38
412
0.92
0.17
3.2
3.4
32.7
31.8
%
0.19
29
297
39
364
1.08
0.13
1.4
1.3
—
—
—
0
0
15
133
1.13
0.12
2.0
2.0
—
—
—
0
0
16
143
1.12
0.11
2.1
2.1
—
—
—
0
0
7
83
0.84
0.07
3.3
1.9
12.1
13.2
%
—
7
83
27
258
1.05
0.05
1.4
1.4
—
—
—
0
0
27
263
1.03
0.01
2.0
1.7
3.6
3.0
mg/l
0.24
19
170
24
245
0.98
0.00
1.9
1.5
—
—
—
0
0
16
156
1.03
0.00
1.5
1.4
52.3
68.9
pmol/l
1.08
16
151
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
7
76
0.92
0.00
1.1
1.8
—
—
—
0
0
5
52
0.96
0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
6.1
—
—
—
0
0
0
6
0.00
0.00
0.0
3.2
—
51.6
—
0
6
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
63
0.95
0.00
1.3
1.5
—
10.6
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED | 2.061 [1.59, 2.68] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.094 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 2142 females with Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED | 2.024 [1.48, 2.77] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 1126 males with Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.212% | 0.457% |
| 5 | 1.159% | 2.853% |
| 10 | 2.828% | 6.949% |
| 15 | 5.402% | 12.6% |
| 20 | 9.606% | 20.54% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_MUSCULOS_SYSTEM_NOT_ELSEW_CLASSIFIED – Congenital malformations of the musculoskeletal system, not elsewhere classified
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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