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Hyphaema and other vascular disorders of iris and ciliary body

DOID EFO Endpoint Browser PheWeb

H7_VASCCILIARY

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H21.0, H21.1
  • Hospital discharge: ICD-9 — 3644
  • Cause of death: ICD-10 — H21.0, H21.1
  • Cause of death: ICD-9 — 3644

2 out of 7 registries used, show all original rules.

761

4. Check minimum number of events

None

761

5. Include endpoints

None

761

6. Filter based on genotype QC (FinnGen only)

730

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5991 2454 3510
Only index persons 5469 2239 3230
Unadjusted period prevalence (%)
Whole population 0.09 0.07 0.10
Only index persons 0.11 0.08 0.12
Median age at first event (years)
Whole population 60.60 71.92 52.62
Only index persons 59.68 71.26 51.65

-FinnGen-

Key figures

All Female Male
Number of individuals 730 315 415
Unadjusted period prevalence (%) 0.16 0.11 0.19
Median age at first event (years) 66.31 66.75 65.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
761
Matched controls
7610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H21.0
ICD-10 Finland
Hyphaema
+∞
307.7
535
*
S01ED51
ATC
timolol, combinations; ophthalmic
23.9
307.7
388
317
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
123.2
307.7
172
18
H43.1
ICD-10 Finland
Vitreous haemorrhage
39.1
279.2
178
59
S01EA05
ATC
brimonidine; ophthalmic
34.4
267.8
178
67
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
266.9
240
*
S01EC01
ATC
acetazolamide; systemic
33.2
246.5
165
63
WX140
NOMESCO Finland
Parabulbar anesthesy
15.7
200.8
193
161
CKC12
NOMESCO Finland
Photocoagulation of retina
16.3
177.1
163
125
S01EE01
ATC
latanoprost; ophthalmic
10.3
158.9
207
266
S01EA03
ATC
apraclonidine; ophthalmic
46.5
157.9
94
23
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
591.5
151.2
145
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
11.7
149.6
172
186
S01ED01
ATC
timolol; ophthalmic
14.8
147.9
142
116
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.1
147.7
309
671
114
Kela drug reimbursment
Glaucoma
8.2
146.3
242
411
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
29.8
145.9
99
38
S01EC54
ATC
brinzolamide, combinations; ophthalmic
35.2
128.1
82
26
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
75.8
127.7
69
10
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
68.9
125.8
69
11
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
18.2
122.0
102
64
S01EC04
ATC
brinzolamide; ophthalmic
11.1
117.8
136
146
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.2
111.5
479
1861
CKC20
NOMESCO Finland
Cryopexy of undetached retina
65.0
108.3
60
10
H3603, E113,
ICD-10 Finland
38.6
107.7
67
19
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.5
107.6
215
434
CKD40
NOMESCO Finland
Endophotocoagulation of retina
23.0
103.6
77
37
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
95.9
90
*
XCK10
NOMESCO Finland
Photography of fundus of eye
6.2
94.3
193
395
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.1
91.1
188
387
CKC15
NOMESCO Finland
Panretinal photocoagulation
31.9
89.8
59
20
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
34.8
86.0
55
17
H16.0
ICD-10 Finland
Corneal ulcer
15.2
84.7
77
56
S01EC03
ATC
dorzolamide; ophthalmic
17.7
81.4
68
42
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
78.2
260
791
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.1
74.9
124
203
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
13.6
73.6
71
57
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
9.6
72.4
90
105
XCK00
NOMESCO Finland
Perimetry
6.4
71.6
132
241
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
19.9
66.2
52
28
H40.0
ICD-10 Finland
Glaucoma suspect
5.6
64.0
138
291
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.5
62.7
408
1900
H34.8
ICD-10 Finland
Other retinal vascular occlusions
10.6
62.5
71
73
S01EE03
ATC
bimatoprost; ophthalmic
10.1
61.9
73
79
H26.2
ICD-10 Finland
Complicated cataract
22.7
60.8
45
21
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.8
56.6
148
366
H26.4
ICD-10 Finland
After-cataract
4.5
55.7
160
426
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
54.7
425
2150
CKC10
NOMESCO Finland
Local photocoagulation of retina
11.0
54.4
60
59
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.3
51.9
60
63
XCH00
NOMESCO Finland
Eye pressure measurement
6.4
51.7
91
157
H33.0
ICD-10 Finland
Retinal detachment with retinal break
8.1
49.6
69
92
H3603, E103,
ICD-10 Finland
72.4
47.8
54
8
S01BC03
ATC
diclofenac; ophthalmic
11.3
46.6
50
47
A10AC01
ATC
insulin (human); parenteral
4.4
46.2
131
343
CHC05
NOMESCO Finland
Iridotomy
14.9
45.4
41
29
A10AA02, ,
ATC
6.8
45.4
75
121
S01BA04
ATC
prednisolone; ophthalmic
10.9
45.3
50
49
A10AB01
ATC
insulin (human); parenteral
6.9
44.8
73
116
A10AE04
ATC
insulin glargine; parenteral
4.0
44.5
146
425
S01BA01
ATC
dexamethasone; ophthalmic
7.5
44.3
66
95
S05.9
ICD-10 Finland
Injury of eye and orbit, unspecified
17.9
43.9
36
21
H3601, E113,
ICD-10 Finland
10.6
43.8
49
49
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
11.3
43.0
46
43
H40.9
ICD-10 Finland
Glaucoma, unspecified
9.0
42.6
54
64
A10AA01, ,
ATC
8.1
41.7
58
77
A10AB05
ATC
insulin aspart; parenteral
4.3
40.5
117
309
S01BA07
ATC
fluorometholone; ophthalmic
13.2
40.3
39
31
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.9
39.5
56
76
S01EX03, ,
ATC
8.2
38.7
53
69
S01EE05
ATC
tafluprost; ophthalmic
6.1
38.5
70
124
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.5
38.3
158
534
H36.01
ICD-10 Finland
Diabetic maculopathy
10.8
38.1
42
41
A10AB04
ATC
insulin lispro; parenteral
7.0
38.0
60
92
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
385.3
37.3
37
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
6.5
36.8
63
105
S01EE04
ATC
travoprost; ophthalmic
8.2
36.1
49
63
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
36.0
316
1613
T89
ICPC
Diabetes insulin dependent
5.8
35.9
69
129
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
4.8
35.0
85
195
S01BC05
ATC
ketorolac; ophthalmic
5.0
33.9
77
167
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
177.7
33.0
34
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
9.0
32.5
41
48
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
39.9
30.5
38
10
XCD20
NOMESCO Finland
Photoangiography of eye
9.0
30.4
38
44
WX002
NOMESCO Finland
Sedation and analgesia
2.7
30.4
203
893
H04AA01
ATC
glucagon; nasal, parenteral
8.4
30.1
40
50
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.5
30.0
44
62
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.2
29.8
64
132
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.1
29.5
87
232
CKD15
NOMESCO Finland
Injection of vitreous substitute
41.9
29.2
36
9
ZXA00
NOMESCO Finland
Right side
2.5
29.0
267
1366
A10AE05
ATC
insulin detemir; parenteral
4.3
28.9
80
203
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.9
28.7
40
53
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
57.4
28.4
33
6
W22
ICD-10 Finland
Striking against or struck by other object(s)
4.1
28.0
83
222
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
5.4
27.7
57
113
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.3
27.7
58
117
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
25.8
26.8
37
15
NHQ40
NOMESCO Finland
Amputation of toe
7.9
26.5
37
49
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.2
26.3
46
78
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
5.3
25.7
54
109
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
5.6
25.3
49
92
CKD20
NOMESCO Finland
Removal of vitreous body substitute
27.3
25.1
34
13
H3601, E103,
ICD-10 Finland
24.4
25.0
35
15
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
20.9
24.5
36
18
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
8.2
24.4
33
42
WX142
NOMESCO Finland
Sub-tenon anesthesy
30.3
24.2
32
11
ZXA10
NOMESCO Finland
Bilateral
2.5
24.2
191
900
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
247.5
23.8
24
*
H26.02
ICD-10 Finland
Presenil cataract
6.7
23.7
38
59
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
7.3
23.5
35
50
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
48.3
23.5
28
6
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
20.2
22.3
33
17
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
22.0
21
*
ZXA05
NOMESCO Finland
Left side
2.3
21.8
232
1240
H3600, E113,
ICD-10 Finland
8.9
20.8
26
30
CS494
NOMESCO Finland
Other visual field testing
5.7
20.7
39
71
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
20.6
98
354
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
20.6
94
332
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.8
20.4
116
462
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
20.4
74
227
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.4
20.3
34
55
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
49.5
20.3
24
5
H57.1
ICD-10 Finland
Ocular pain
5.2
20.2
42
84
S01FA04
ATC
cyclopentolate; ophthalmic
21.5
20.1
29
14
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.5
19.8
50
118
CHD00
NOMESCO Finland
Laser trabeculoplasty
7.6
19.6
28
38
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
18.8
19.2
29
16
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
18.8
18
*
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
7.3
18.3
27
38
S01FA02
ATC
scopolamine; ophthalmic
27.5
17.9
24
9
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
20.7
17.8
26
13
A10AD01
ATC
insulin (human); parenteral
5.6
17.7
34
63
H27.1
ICD-10 Finland
Dislocation of lens
29.6
17.5
23
8
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.5
17.3
63
193
TK800
NOMESCO Finland
Hemodialysis
5.6
17.3
33
61
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.8
17.1
27
41
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
19.8
17.0
25
13
A10AE06
ATC
insulin degludec; parenteral
4.4
16.7
43
103
L01BA01
ATC
methotrexate; systemic
4.4
16.7
43
103
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
16.7
63
198
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
173.7
16.6
17
*
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
41.1
16.4
20
5
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
12.0
16.2
29
25
C03CA01
ATC
furosemide; systemic
1.9
15.6
288
1842
ZXD05
NOMESCO Finland
Urgent procedure
1.9
15.6
252
1542
H36.00
ICD-10 Finland
Diabetic background retinopathy
6.6
15.5
25
39
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
15.2
15.4
25
17
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.2
15.4
32
64
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.6
15.3
29
53
H3600, E103,
ICD-10 Finland
13.4
15.3
26
20
H40.8
ICD-10 Finland
Other glaucoma
20.5
15.2
22
11
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
15.1
241
1465
L04AA06
ATC
mycophenolic acid; systemic
6.4
15.1
25
40
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.1
14.9
26
44
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
14.5
14.6
24
17
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.9
14.6
32
67
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
4.8
14.6
33
71
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
14.3
209
1229
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
4.2
14.3
38
93
Z3231
NOMESCO Finland
Registered nurse
1.9
14.2
227
1378
L04AB04
ATC
adalimumab; parenteral
6.4
13.8
23
37
CG2S4
NOMESCO Finland
Photography of cornea
76.5
13.6
15
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.6
13.4
32
72
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.2
13.4
36
89
TCG10
NOMESCO Finland
Removal of sutures from cornea
26.3
13.4
18
7
B03XA02
ATC
darbepoetin alfa; parenteral
4.7
13.4
31
68
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.9
13.3
26
27
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
40.8
13.2
16
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
15.4
13.2
21
14
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.6
13.1
43
123
L04AA01
ATC
[U] ciclosporin
11.2
13.1
24
22
H16.9
ICD-10 Finland
Keratitis, unspecified
50.9
12.9
15
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
12.7
68
261
H25.8
ICD-10 Finland
Other senile cataract
2.3
12.7
107
509
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.7
12.6
73
292
H34.1
ICD-10 Finland
Central retinal artery occlusion
13.5
12.5
21
16
H44.5
ICD-10 Finland
Degenerated conditions of globe
132.1
12.5
13
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.1
12.4
54
185
H54.4
ICD-10 Finland
Blindness, monocular
38.2
12.2
15
*
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
5.0
12.2
26
53
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
12.2
263
1736
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
12.1
80
342
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.5
11.9
23
43
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
11.9
277
1869
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
11.8
148
820
CKD60
NOMESCO Finland
Anterior vitrectomy
9.8
11.8
23
24
CHD99
NOMESCO Finland
Other filtering operation
19.3
11.6
17
9
J01FF01
ATC
clindamycin; systemic
1.8
11.5
209
1307
H26.3
ICD-10 Finland
Drug-induced cataract
13.9
11.5
19
14
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
11.5
11
*
3644A
ICD-9 Finland
Disorders of iris and ciliary body, Vascular disorders of iris and ciliary body
+∞
11.5
11
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
11.4
206
1285
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.3
11.3
91
424
XCH05
NOMESCO Finland
Eye pressure longterm registration
10.8
11.3
21
20
I50.0
ICD-10 Finland
Congestive heart failure
2.4
11.2
82
367
A02BC02
ATC
pantoprazole; systemic
1.7
11.2
494
3944
A11CC03
ATC
alfacalcidol; systemic
4.1
11.0
30
75
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
14.1
11.0
18
13
C08CA01
ATC
amlodipine; oral
1.7
11.0
301
2114
H35.36
ICD-10 Finland
Macular cyst
15.8
10.9
17
11
S01FA01
ATC
atropine; ophthalmic
15.8
10.9
17
11
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
18.1
10.8
16
9
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
28.5
10.8
14
5
J01DB01
ATC
cefalexin; oral
1.9
10.7
604
5135
ZX198
NOMESCO Finland
Other local administration
8.7
10.6
22
26
S01AD03
ATC
aciclovir; ophthalmic
4.0
10.5
30
78
H54.1
ICD-10 Finland
Severe visual impairment, binocular
111.5
10.4
11
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
10.4
119
636
H221, M084,
ICD-10 Finland
+∞
10.4
10
*
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
10.4
10
*
C07AB07
ATC
bisoprolol; oral
1.7
10.4
383
2892
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
10.4
68
289
V03AE01
ATC
polystyrene sulfonate; oral
5.2
10.4
21
41
SPAT1262
SPAT
Handing over of treatment supplies
1.9
10.3
143
818
L04AD01
ATC
ciclosporin; systemic
5.0
10.3
22
45
H33.3
ICD-10 Finland
Retinal breaks without detachment
3.6
10.3
34
98
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
23.7
10.3
14
6
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
13.3
10.2
17
13
L04AX03
ATC
methotrexate; systemic
2.4
10.2
74
330
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
4.4
10.1
25
58
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.2
10.0
40
130
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
4.1
10.0
27
67
B01AC04
ATC
clopidogrel; oral
1.9
9.9
149
874
N18.8
ICD-10 Finland
Other chronic renal failure
4.0
9.9
28
72
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.8
9.8
18
17
H18.8
ICD-10 Finland
Other specified disorders of cornea
55.7
9.7
11
*
N18.0
ICD-10 Finland
End-stage renal disease
8.0
9.7
21
27
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.2
9.6
19
21
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
101.3
9.4
10
*
H54.0
ICD-10 Finland
Blindness, binocular
101.3
9.4
10
*
H3603, E107,
ICD-10 Finland
101.3
9.4
10
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
9.4
9
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
12.5
9.4
16
13
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.7
9.3
18
19
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
7.4
9.3
21
29
QDA10
NOMESCO Finland
Incision of skin of lower limb
13.9
9.2
15
11
A12AA04
ATC
calcium carbonate; oral
5.1
9.1
19
38
N19
ICD-10 Finland
Unspecified kidney failure
3.0
9.0
41
144
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
37.2
9.0
11
*
V03AE02
ATC
sevelamer; oral
18.9
9.0
13
7
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
8.9
170
1070
Z49.0
ICD-10 Finland
Preparatory care for dialysis
9.6
8.8
17
18
H40
ICD-10 Finland
Glaucoma
7.3
8.8
20
28
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
8.8
55
229
CG2T4
NOMESCO Finland
Topography assessment of cornea
14.2
8.7
14
10
H3602, E103,
ICD-10 Finland
50.6
8.7
10
*
L04AD02
ATC
tacrolimus; systemic
10.2
8.6
16
16
127
Kela drug reimbursment
Transplant complication
6.5
8.5
21
33
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.8
8.5
26
71
S18
ICPC
Laceration/cut
1.6
8.5
328
2467
CA1AD
NOMESCO Finland
Orbita CT
91.0
8.4
9
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
8.4
57
246
A10BB01
ATC
glibenclamide; oral
2.7
8.4
46
179
C09AA02
ATC
enalapril; systemic
1.8
8.4
159
997
H26.1
ICD-10 Finland
Traumatic cataract
12.9
8.4
14
11
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
8.3
8
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
8.3
8
*
CH2S4
NOMESCO Finland
Photography of iris
+∞
8.3
8
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
8.3
96
514
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
14.7
8.2
13
9
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.0
8.2
23
59
CHD35
NOMESCO Finland
Laser goniopuncture
11.9
8.1
14
12
CD2S4
NOMESCO Finland
Photography of eye
11.9
8.1
14
12
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
33.7
8.1
10
*
H30.2
ICD-10 Finland
Posterior cyclitis
33.7
8.1
10
*
H33.4
ICD-10 Finland
Traction detachment of retina
17.4
8.1
12
7
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
8.1
184
1213
Z94.0
ICD-10 Finland
Kidney transplant status
9.1
8.1
16
18
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
7.9
342
2625
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.9
7.8
23
61
ZXE00
NOMESCO Finland
One hour or less
1.6
7.8
270
1970
N02BE01
ATC
paracetamol; systemic, rectal
1.8
7.8
646
5761
Z2221
NOMESCO Finland
Medical doctor
1.7
7.8
191
1282
WW200
NOMESCO Finland
Immunization
3.6
7.7
25
71
196
Kela drug reimbursment
Paricalcitol and cinacalcet
15.2
7.7
12
8
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
45.4
7.7
9
*
L28
ICPC
Limited function/disability (L)
1.8
7.7
141
875
C02AC05
ATC
moxonidine; oral
2.6
7.6
44
176
A28
ICPC
Limited function/disability NOS
1.7
7.6
144
901
L04AA17
ATC
[U] adalimumab
25.3
7.6
10
*
L04AB06
ATC
golimumab; parenteral
10.2
7.6
14
14
H01
ICPC
Ear pain/earache
2.0
7.5
78
402
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
7.5
77
396
S97
ICPC
Chronic ulcer skin
2.3
7.5
57
260
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
6.6
7.4
18
28
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
80.9
7.4
8
*
RJ521, ,
NOMESCO Finland
80.9
7.4
8
*
H35.6
ICD-10 Finland
Retinal haemorrhage
7.8
7.4
16
21
C10AA05
ATC
atorvastatin; oral
1.5
7.4
298
2246
W20
ICD-10 Finland
Struck by thrown, projected or falling object(s)
6.9
7.3
17
25
M45
ICD-10 Finland
Ankylosing spondylitis
4.2
7.3
19
46
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
+∞
7.3
7
*
H3603, E117,
ICD-10 Finland
+∞
7.3
7
*
AN1
HP
Coronary angiography
1.9
7.3
97
546
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
4.0
7.2
20
51
E0000UV, ,
ATC
1.5
7.2
282
2109
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
20.2
7.1
10
5
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
20.2
7.1
10
5
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.1
207
1447
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.4
7.1
49
214
Z49.2
ICD-10 Finland
Other dialysis
10.2
7.1
13
13
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
4.3
7.0
18
43
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
3.6
7.0
23
66
A07AA09
ATC
vancomycin; oral
4.4
7.0
17
39
SPAT1009
SPAT
Measurement of intraocular pressure
5.5
6.9
19
35
H02AB06
ATC
prednisolone; systemic
1.5
6.9
332
2585
H27.0
ICD-10 Finland
Aphakia
13.9
6.9
11
8
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.3
6.9
49
217
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
6.9
87
481
H34.2
ICD-10 Finland
Other retinal artery occlusions
8.4
6.8
14
17
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
4.2
6.8
18
44
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
6.8
6.8
16
24
S01EB01
ATC
pilocarpine; ophthalmic
6.8
6.8
16
24
1LA05, ,
NOMESCO Finland
11.1
6.8
12
11
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
11.1
6.8
12
11
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.8
194
1347
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.8
442
3658
H44.0
ICD-10 Finland
Purulent endophthalmitis
40.4
6.8
8
*
CKD50
NOMESCO Finland
Endodiathermy of retina
16.9
6.8
10
6
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.0
6.7
77
411
205
Kela drug reimbursment
Chronic hypertension
1.6
6.7
213
1514
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.1
6.7
61
299
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
22.7
6.7
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
6.7
132
835
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
7.9
6.6
14
18
A10BX01
ATC
guar gum; oral
2.6
6.6
37
146
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.6
99
579
C10AA01
ATC
simvastatin; oral
1.5
6.5
320
2494
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.5
6.5
40
166
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.4
6.5
23
70
X57
ICD-10 Finland
Unspecified privation
3.4
6.5
23
70
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
70.4
6.4
7
*
CJF20
NOMESCO Finland
Removal of artificial lens
70.4
6.4
7
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
70.4
6.4
7
*
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
70.4
6.4
7
*
A46
ICD-10 Finland
Erysipelas
1.7
6.4
113
692
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
6.4
46
205
C09AA05
ATC
ramipril; oral
1.6
6.4
199
1409
WX213
NOMESCO Finland
Lower leg blockade
8.2
6.3
13
16
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.3
152
1010
S01ED02
ATC
betaxolol; ophthalmic
5.6
6.3
17
31
ZX120
NOMESCO Finland
Intravenous
2.0
6.3
72
384
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
11.1
6.3
11
10
F28
ICPC
Limited function/disability (F)
9.4
6.3
12
13
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.9
6.3
18
47
H01.0
ICD-10 Finland
Blepharitis
2.4
6.3
42
181
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.3
187
1309
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
6.3
6
*
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
6.3
6
*
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
+∞
6.3
6
*
H221, M083,
ICD-10 Finland
+∞
6.3
6
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
26.9
6.2
8
*
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.2
6.2
24
77
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
7.8
6.1
13
17
Z5132
NOMESCO Finland
Nursing associate professional
7.8
6.1
13
17
L04AB05
ATC
certolizumab pegol; parenteral
12.6
6.1
10
8
H35.8
ICD-10 Finland
Other specified retinal disorders
8.7
6.1
12
14
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.4
6.1
39
165
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.1
6.0
11
11
PE1AT
NOMESCO Finland
Femoral artery PTA
3.9
6.0
17
44
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.3
6.0
43
191

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
155
700
2.52
21.26
2.4
1.6
—
—
—
0
0
166
867
2.17
15.89
4.9
2.4
21.36
22.49
%
0.51
141
742
167
913
2.06
14.03
4.8
2.3
2.14
2.30
g/l
3.29
151
842
176
981
2.03
14.02
4.7
2.4
11.76
12.75
umol/l
1.04
163
915
284
1891
1.80
12.98
5.0
3.2
6.84
7.70
mmol/l
2.27
242
1593
270
1777
1.81
12.79
5.2
3.3
612.94
326.03
mg/l
0.44
194
1175
373
2707
1.74
12.52
8.5
6.2
—
—
—
0
0
278
1877
1.76
11.89
5.8
3.9
20.18
9.89
mg/mmol
1.74
192
1223
73
301
2.58
11.86
1.8
2.1
1.83
1.50
g/l
1.93
64
263
401
2999
1.71
11.83
7.9
5.9
0.20
0.19
e9/l
0.52
356
2657
372
2727
1.71
11.81
7.7
5.7
2.80
2.89
%
0.29
351
2566
391
2909
1.71
11.72
7.7
5.6
0.04
0.04
e9/l
0.09
346
2546
456
3538
1.72
11.70
7.4
4.9
7.60
6.75
mmol/l
7.31
436
3321
398
2977
1.71
11.68
7.9
5.7
1.79
1.89
e9/l
1.00
349
2653
136
734
2.04
11.68
3.2
2.6
1.73
1.79
%
0.33
120
663
363
2649
1.71
11.67
8.1
5.8
0.66
0.65
%
0.18
342
2488
390
2903
1.70
11.64
7.7
5.6
0.61
0.59
e9/l
0.83
347
2533
373
2747
1.70
11.55
11.2
5.9
1.20
1.21
mmol/l
1.33
340
2480
372
2741
1.70
11.47
8.3
6.0
8.74
8.74
%
0.00
352
2585
341
2460
1.70
11.34
2.4
2.0
86.91
94.68
pmol/l
2.28
188
1276
528
4285
1.76
11.34
5.2
4.0
15.84
12.69
mm/h
3.64
494
3935
38
111
3.55
11.25
1.9
1.4
—
—
—
0
0
392
2945
1.68
11.11
22.5
16.5
1.23
1.30
inr
0.77
101
873
142
792
1.97
11.08
15.3
5.4
1.13
1.02
mmol/l
3.93
134
722
376
2802
1.68
10.93
8.2
5.8
25.72
27.16
%
1.76
354
2647
94
452
2.23
10.84
7.3
3.6
134.23
86.95
ng/l
2.69
83
391
35
100
3.62
10.71
1.8
1.4
109.27
103.50
u/ml
0.19
11
18
371
2765
1.67
10.71
7.9
5.6
58.43
57.67
%
0.56
351
2614
257
1744
1.72
10.53
5.8
4.2
—
—
—
0
0
393
2999
1.64
10.14
13.4
6.6
1.20
1.21
mmol/l
1.22
346
2530
24
54
4.56
10.08
1.1
1.2
—
—
—
0
0
68
295
2.43
9.92
8.1
3.7
23.37
24.07
mmol/l
1.14
68
289
160
962
1.84
9.86
3.5
3.4
0.82
0.82
mmol/l
0.07
155
900
261
1817
1.66
9.53
2.5
2.1
253.03
251.50
u/l
0.01
248
1708
124
694
1.94
9.50
1.5
1.3
534.19
445.18
titre
0.30
31
139
39
131
3.08
9.28
4.5
2.5
—
—
—
0
0
188
1206
1.74
9.25
1.9
1.7
1159.47
1187.65
nmol/l
0.14
156
906
99
519
2.04
9.12
12.3
7.8
—
—
—
0
0
257
1811
1.63
8.81
7.9
4.0
7.38
7.40
ph
2.25
42
341
150
916
1.79
8.70
3.0
2.1
—
—
—
0
0
53
219
2.53
8.59
2.9
2.3
824.79
394.82
ug/l
0.57
53
207
477
3905
1.59
8.57
6.2
4.7
687.09
4072.11
e6/l
1.28
11
63
659
5879
1.90
8.43
24.0
15.0
24.12
25.60
mg/l
0.65
552
4697
360
2775
1.56
8.31
3.7
2.6
—
—
—
0
0
226
1564
1.63
8.23
3.0
2.2
3.12
3.15
mg/l
0.07
199
1316
491
4072
1.58
8.12
6.2
4.3
—
—
—
0
0
107
600
1.91
8.11
8.4
3.6
1.10
1.98
mmol/l
1.69
96
484
263
1896
1.59
8.06
3.8
2.5
—
—
—
0
0
311
2331
1.57
8.06
2.8
2.3
75.05
76.59
nmol/l
0.41
279
2051
57
254
2.34
7.86
1.4
1.5
—
12.56
—
0
7
222
1546
1.62
7.82
3.2
2.7
376.44
6792.06
umol/l
6.24
190
1346
421
3392
1.54
7.77
9.8
8.9
4.35
4.22
e9/l
0.54
372
2999
99
550
1.92
7.71
3.8
2.6
65.01
69.65
e9/l
0.57
77
442
23
62
3.79
7.67
2.5
2.4
—
—
—
0
0
325
2481
1.54
7.64
4.7
2.7
148.36
143.68
ug/l
0.14
304
2248
32
109
3.02
7.47
1.3
1.2
288.21
223.00
u/ml
0.80
24
62
123
743
1.78
7.33
7.2
7.1
0.36
1.28
mmol/l
1.53
103
577
22
60
3.75
7.23
1.3
1.2
—
—
—
0
0
336
2611
1.51
7.13
7.9
4.8
34.13
35.29
g/l
3.47
314
2418
21
57
3.76
6.95
1.2
1.2
—
—
—
0
0
528
4531
1.54
6.83
9.7
7.6
82.30
79.49
u/l
0.67
507
4249
201
1428
1.55
6.32
4.2
2.4
—
—
—
0
0
12
13
9.36
6.30
5.3
4.4
—
—
—
0
0
383
3112
1.46
6.23
6.0
6.3
12.09
11.84
umol/l
0.12
366
2945
253
1894
1.50
6.22
3.7
3.2
3196.09
1561.74
ng/l
2.08
223
1629
593
5269
1.57
6.12
5.2
4.5
5.27
2.18
mu/l
0.47
543
4768
88
509
1.82
6.04
1.7
3.1
66.73
66.34
g/l
0.17
81
457
601
5367
1.57
5.95
8.7
5.9
45.11
40.14
mmol/mol
12.77
558
4942
660
6030
1.71
5.95
29.6
17.7
139.46
139.59
mmol/l
0.70
649
5863
170
1185
1.56
5.76
1.4
1.2
1.92
1.80
u/ml
0.04
47
311
660
6044
1.69
5.72
30.3
17.9
4.02
3.99
mmol/l
1.82
649
5869
266
2039
1.47
5.72
3.9
3.3
2.34
2.35
mmol/l
0.35
227
1782
75
421
1.87
5.66
1.8
2.7
—
—
—
0
0
104
645
1.71
5.62
2.4
1.6
—
—
—
0
0
100
618
1.71
5.47
8.2
7.8
117.13
120.97
g/l
1.08
100
600
152
1052
1.56
5.28
1.4
1.5
2.52
2.54
g/l
0.05
95
636
26
98
2.71
5.12
7.0
2.8
—
—
—
0
0
34
147
2.37
5.08
1.7
4.2
—
—
—
0
0
635
5803
1.57
5.05
5.9
4.9
2.52
2.68
mmol/l
4.02
592
5289
200
1481
1.48
5.03
1.8
1.6
18.74
20.47
nmol/l
0.82
172
1240
12
20
6.08
4.92
2.2
1.6
—
—
—
0
0
78
463
1.76
4.92
4.3
4.7
—
—
—
0
0
291
2325
1.41
4.81
4.4
3.5
5.67
5.82
ph
0.33
15
157
300
2413
1.40
4.76
4.8
3.8
51.75
43.33
ng/l
0.43
227
1755
91
571
1.67
4.71
2.7
2.5
5.28
7.27
ug/l
1.14
77
504
138
958
1.54
4.70
2.4
1.8
—
—
—
0
0
41
200
2.11
4.63
2.0
3.9
39.38
34.70
mg/l
0.31
33
165
41
200
2.11
4.63
2.0
3.9
64.47
92.64
mg/l
0.40
34
165
194
1450
1.45
4.60
6.3
6.6
—
—
—
0
0
240
1867
1.42
4.58
4.3
3.3
—
—
—
0
0
8
8
10.09
4.52
20.8
3.4
5.72
7.65
mmol/l
—
8
8
165
1200
1.48
4.49
5.4
4.0
225.18
287.33
ng/l
0.32
145
971
115
774
1.57
4.49
2.4
1.6
—
—
—
0
0
617
5648
1.49
4.41
5.2
4.3
1.38
1.43
mmol/l
1.70
576
5157
56
311
1.86
4.40
1.6
1.2
—
—
—
0
0
240
1878
1.41
4.40
4.2
2.5
55.38
98.85
u/l
0.52
221
1750
37
177
2.15
4.40
1.3
1.2
—
—
—
0
0
69
412
1.74
4.29
4.7
3.5
7.36
7.41
ph
—
6
42
48
256
1.93
4.27
5.4
4.1
24.60
24.92
mmol/l
0.32
43
239
71
429
1.72
4.23
4.5
4.2
0.55
0.59
%
0.08
28
149
668
6238
1.58
4.14
14.0
10.4
26.21
26.46
u/l
0.13
654
6004
484
4267
1.37
4.12
4.2
3.7
15.16
14.91
pmol/l
1.37
445
3833
77
480
1.67
4.10
4.9
4.2
0.93
0.93
%
0.00
29
179
102
682
1.57
4.10
2.9
2.7
10.12
9.34
umol/l
0.12
88
595
26
111
2.39
4.03
5.0
2.2
70.91
60.86
%
1.40
26
111
9
14
6.49
3.99
1.1
1.0
—
—
—
0
0
611
5614
1.45
3.99
5.4
4.6
6.49
5.99
mmol/l
5.88
555
5050
310
2563
1.35
3.96
12.7
9.7
0.00
0.00
e9/l
0.26
259
2118
618
5693
1.46
3.95
5.1
4.4
4.33
4.55
mmol/l
5.15
575
5236
35
172
2.08
3.91
1.7
1.5
207.34
285.60
ug/g
1.60
23
103
11
23
4.84
3.88
1.1
1.2
—
—
—
0
0
10
19
5.32
3.83
1.0
1.0
1103.60
1310.74
miu/ml
—
10
19
17
60
2.88
3.81
3.1
2.9
2.95
1.97
g/24h
—
6
31
71
442
1.67
3.81
1.7
1.7
—
—
—
0
0
72
451
1.66
3.78
4.4
4.3
0.17
0.12
%
0.23
24
149
344
2904
1.34
3.77
4.8
3.8
0.00
0.01
estimate
0.50
51
541
468
4135
1.34
3.75
4.6
4.0
—
—
—
0
0
20
78
2.61
3.74
7.9
5.4
12.29
11.34
mg/l
0.46
20
71
340
2868
1.34
3.74
6.2
5.1
0.00
0.00
estimate
-0.00
57
563
210
1646
1.38
3.72
4.3
3.2
—
—
—
0
0
123
875
1.48
3.71
1.3
1.2
30.77
37.55
iu/ml
0.36
39
264
173
1315
1.41
3.67
5.4
3.9
—
—
—
0
0
80
520
1.60
3.63
2.0
1.9
351.52
381.88
nmol/l
0.80
75
479
140
1027
1.45
3.61
3.4
2.9
1.22
1.00
e6/l
0.31
83
604
593
5451
1.40
3.59
4.7
3.9
1.33
1.29
mmol/l
0.45
549
4944
340
2883
1.32
3.55
4.8
3.8
0.00
0.00
estimate
-0.00
64
601
690
6533
1.60
3.55
35.6
22.0
39.18
40.23
%
3.33
648
6066
166
1262
1.40
3.51
1.6
1.7
1.00
1.25
mg/l
1.21
124
958
21
87
2.45
3.50
1.1
1.0
—
—
—
0
0
690
6537
1.60
3.49
35.0
21.8
91.05
91.08
fl
0.04
684
6428
690
6537
1.60
3.49
34.9
21.8
30.18
30.35
pg
1.75
684
6428
690
6537
1.60
3.49
35.1
21.9
6.95
6.79
e9/l
1.17
677
6338
690
6538
1.59
3.48
35.1
21.9
4.41
4.50
e12/l
3.99
676
6340
690
6540
1.59
3.45
35.4
22.0
132.11
135.76
g/l
6.57
683
6426
79
520
1.58
3.41
4.8
3.5
—
—
—
0
0
689
6533
1.58
3.38
35.2
21.9
243.79
243.52
e9/l
0.03
676
6356
68
433
1.63
3.36
4.0
4.3
0.05
0.80
%
0.59
20
134
100
696
1.50
3.36
1.8
1.4
—
—
—
0
0
30
148
2.07
3.35
1.4
1.2
80.00
78.46
titre
—
5
13
34
176
1.98
3.34
5.3
3.3
—
—
—
0
0
261
2152
1.32
3.26
5.6
3.8
80.10
138.04
e6/l
0.67
205
1541
169
1305
1.38
3.24
5.4
4.3
1.02
1.02
kg/l
0.17
24
190
231
1874
1.33
3.22
4.8
3.4
70.79
112.26
e6/l
0.47
187
1450
10
24
4.21
3.20
2.8
2.2
—
—
—
0
0
35
186
1.92
3.20
1.4
1.2
0.82
2.04
u/ml
—
9
14
63
399
1.63
3.19
1.3
1.2
—
—
—
0
0
131
971
1.42
3.19
3.6
3.1
1.75
1.90
e6/l
0.14
75
551
32
166
1.97
3.14
2.9
2.3
245.34
97.64
ug/min
0.45
17
102
231
1882
1.33
3.11
3.1
3.3
37.08
33.05
u/l
0.48
220
1787
44
255
1.77
3.08
1.4
1.2
—
—
—
0
0
55
340
1.67
3.07
11.4
9.6
—
—
—
0
0
6
8
7.55
3.06
1.7
1.8
84.00
103.75
ng/l
—
6
8
551
5055
1.33
3.02
28.3
17.8
15.36
14.97
%
0.79
544
4973
8
17
4.74
2.92
1.0
1.1
—
—
—
0
0
50
306
1.68
2.91
5.0
3.6
—
—
—
0
0
34
187
1.86
2.83
17.8
11.3
—
—
—
0
0
210
1709
1.32
2.82
4.4
3.2
0.22
0.54
e6/l
3.36
166
1302
8
18
4.48
2.80
1.0
1.0
—
—
—
0
0
648
6116
1.40
2.78
23.1
14.2
—
—
—
0
0
23
111
2.11
2.75
11.4
1.8
0.81
0.84
nmol/l
0.08
17
93
78
540
1.50
2.71
4.7
2.5
28.01
31.61
u/l
0.86
68
460
23
113
2.07
2.64
1.2
1.2
42.29
34.60
u/l
0.15
18
98
166
1324
1.32
2.55
4.0
2.6
4.96
4.64
e6/l
0.17
156
1182
187
1517
1.31
2.54
1.6
1.6
1.47
1.38
mmol/l
0.54
165
1257
426
3826
1.26
2.52
3.4
3.1
54.84
51.10
u/l
0.35
406
3556
16
69
2.35
2.49
4.1
2.7
—
—
—
0
0
81
581
1.44
2.38
10.9
4.3
—
—
—
0
0
12
46
2.63
2.37
1.9
1.7
9.04
10.51
%
0.55
12
46
42
261
1.64
2.35
6.5
4.6
—
—
—
0
0
21
105
2.03
2.32
1.2
1.2
—
—
—
0
0
23
124
1.88
2.09
2.5
2.1
122.73
127.30
g/l
0.33
15
92
83
615
1.39
2.05
1.3
1.3
—
—
—
0
0
8
26
3.10
2.01
3.5
18.3
—
—
—
0
0
18
91
2.00
1.96
1.1
1.0
—
—
—
0
0
5
141
0.35
1.89
1.6
1.6
—
—
—
0
0
24
136
1.79
1.89
1.3
1.7
—
—
—
0
0
23
129
1.81
1.87
4.7
3.7
—
—
—
0
0
67
489
1.41
1.83
1.4
1.4
—
—
—
0
0
144
1180
1.27
1.80
3.7
3.1
2.47
2.45
mmol/l
0.96
126
1034
98
766
1.32
1.75
1.3
1.2
—
—
—
0
0
187
1586
1.24
1.73
5.6
4.2
0.00
0.01
estimate
0.69
55
535
45
308
1.49
1.72
2.3
2.5
—
—
—
0
0
53
375
1.44
1.72
3.7
3.1
—
—
—
0
0
43
293
1.50
1.69
1.9
3.3
4.09
4.50
pmol/l
1.79
37
253
250
2191
1.21
1.68
2.2
2.2
—
—
—
0
0
20
112
1.81
1.66
2.7
2.5
—
—
—
0
0
7
25
2.82
1.65
4.0
1.9
0.12
0.14
e9/l
—
7
25
10
42
2.40
1.62
4.8
2.8
—
—
—
0
0
5
15
3.35
1.52
5.0
6.5
—
—
—
0
0
19
108
1.78
1.52
2.1
1.6
—
—
—
0
0
7
27
2.61
1.51
1.0
1.0
—
—
—
0
0
28
179
1.59
1.47
1.3
1.1
—
—
—
0
0
10
45
2.24
1.47
1.3
1.5
—
—
—
0
0
10
45
2.24
1.47
1.4
1.3
2.28
1.29
promille
—
10
35
21
125
1.70
1.45
2.6
1.7
5.18
7.35
iu/l
—
9
37
12
59
2.05
1.44
1.7
2.7
—
—
—
0
0
5
16
3.14
1.44
1.4
1.4
—
—
—
0
0
39
271
1.46
1.42
2.7
2.8
—
—
—
0
0
103
835
1.27
1.42
1.3
1.2
4.13
10.04
u/ml
1.03
37
300
59
442
1.36
1.42
2.5
2.7
11.27
10.56
g/l
0.45
53
397
56
421
1.36
1.33
1.7
1.4
—
—
—
0
0
80
635
1.29
1.31
2.0
2.3
245.32
120.94
ug/g
0.83
68
503
19
114
1.68
1.29
2.8
3.1
4.80
4.61
e9/l
0.15
19
114
20
122
1.66
1.28
3.0
2.3
15.31
16.02
%
0.25
11
60
150
1284
1.21
1.27
3.5
2.9
509.86
554.09
mosm/kgh2o
2.08
130
1091
6
25
2.41
1.24
1.0
1.0
—
—
—
0
0
6
25
2.41
1.24
1.7
1.2
153.50
189.63
mmol/24h
—
6
25
18
108
1.68
1.23
1.4
1.5
—
—
—
0
0
45
335
1.36
1.16
1.1
1.2
185.65
138.36
iu/ml
0.23
16
128
19
118
1.63
1.15
3.4
3.3
61.89
59.88
%
0.30
19
118
25
167
1.51
1.13
1.2
1.1
—
—
—
0
0
8
40
2.01
1.12
3.8
2.1
690.00
585.03
e6/l
—
8
40
8
40
2.01
1.12
1.3
1.0
—
—
—
0
0
13
73
1.79
1.11
1.3
1.2
—
—
—
0
0
260
2362
1.15
1.08
4.5
5.0
2.19
3.14
ug/l
1.23
223
2098
21
137
1.55
1.06
7.0
4.7
2.24
2.70
mmol/l
0.34
16
87
7
33
2.13
1.05
3.9
3.5
76.00
108.00
nmol/l
—
7
33
175
1968
0.86
1.03
3.0
2.8
—
—
—
0
0
7
34
2.07
1.03
3.7
1.9
—
—
—
0
0
21
140
1.51
0.98
2.9
4.1
18.17
28.85
mg/l
1.37
12
89
0
30
0.00
0.97
0.0
1.2
—
2.44
—
0
8
148
1300
1.17
0.96
1.9
1.7
427.22
16114177.65
pmol/l
1.04
125
1055
9
51
1.77
0.94
1.0
1.1
—
—
—
0
0
15
94
1.61
0.91
3.6
1.8
—
—
—
0
0
14
217
0.64
0.88
2.1
1.6
—
—
—
0
0
18
121
1.50
0.83
2.9
2.4
2444.80
3994.06
u/l
—
5
44
11
65
1.70
0.82
4.8
4.9
—
—
—
0
0
8
47
1.71
0.81
2.3
1.6
—
—
—
0
0
10
58
1.73
0.80
4.7
3.2
—
—
—
0
0
47
377
1.26
0.78
3.9
2.9
4.20
7.82
e9/l
1.16
30
302
0
27
0.00
0.77
0.0
1.0
—
11.34
—
0
7
176
1596
1.13
0.74
3.7
3.4
—
—
—
0
0
9
57
1.59
0.71
1.2
1.2
—
—
—
0
0
42
337
1.26
0.70
5.0
2.9
0.07
0.25
e6/l
3.04
42
325
7
41
1.71
0.70
1.4
2.0
47.14
38.04
%
—
7
41
60
503
1.21
0.68
9.3
3.7
1.21
1.22
mmol/l
1.08
53
431
7
42
1.67
0.68
2.1
1.3
—
—
—
0
0
7
42
1.67
0.68
1.3
1.1
—
—
—
0
0
31
240
1.30
0.68
4.9
3.5
0.40
0.28
g/l
0.54
19
100
173
1580
1.12
0.66
1.4
1.4
—
—
—
0
0
84
730
1.17
0.65
1.3
1.3
—
—
—
0
0
63
535
1.19
0.64
1.5
1.5
—
—
—
0
0
24
182
1.33
0.62
1.8
1.6
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
150.60
141.45
nmol/l
—
5
30
5
30
1.67
0.61
1.4
1.3
—
—
—
0
0
13
88
1.49
0.61
3.9
1.9
32.85
33.06
pg
0.07
13
88
57
483
1.19
0.60
1.4
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
11.97
—
0
9
40
485
0.82
0.59
1.4
1.4
—
—
—
0
0
19
142
1.35
0.55
1.4
1.4
131.63
261.78
miu/ml
—
8
78
10
145
0.69
0.51
1.2
1.2
—
—
—
0
0
17
127
1.35
0.50
1.2
1.2
—
—
—
0
0
37
308
1.21
0.49
1.4
1.3
224.64
220.83
u/ml
0.01
31
279
7
110
0.63
0.48
1.6
1.4
—
—
—
0
0
24
191
1.26
0.47
1.1
1.2
—
—
—
0
0
147
1362
1.10
0.45
2.7
3.0
0.75
0.79
ug/l
0.25
89
870
12
86
1.40
0.44
1.3
1.1
—
—
—
0
0
48
552
0.86
0.43
1.5
1.6
—
—
—
0
0
8
56
1.43
0.42
1.3
1.2
—
—
—
0
0
8
57
1.41
0.42
1.4
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
2.47
—
0
8
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.7
—
—
—
0
0
13
97
1.35
0.39
1.2
1.3
—
—
—
0
0
14
106
1.33
0.39
1.3
1.5
—
—
—
0
0
9
71
1.27
0.36
1.2
1.2
—
—
—
0
0
6
42
1.43
0.35
3.2
3.2
—
—
—
0
0
6
90
0.66
0.33
1.3
2.6
—
—
—
0
0
27
316
0.85
0.32
2.8
3.5
—
—
—
0
0
58
523
1.12
0.32
2.6
2.2
13.04
13.58
nmol/l
0.21
47
471
185
1763
1.07
0.30
5.1
4.1
—
—
—
0
0
15
184
0.81
0.29
2.9
4.3
—
—
—
0
0
8
64
1.25
0.27
1.1
1.0
—
—
—
0
0
29
330
0.87
0.25
1.4
1.4
—
—
—
0
0
12
96
1.25
0.24
1.6
1.4
—
—
—
0
0
6
81
0.74
0.24
1.2
1.0
2.32
3.57
u/ml
—
6
40
6
83
0.72
0.24
2.3
1.1
—
—
—
0
0
6
84
0.71
0.24
1.2
1.0
11.93
8.26
u/ml
—
6
50
6
84
0.71
0.24
2.3
1.1
—
—
—
0
0
36
323
1.12
0.23
1.3
1.2
—
—
—
0
0
17
200
0.85
0.23
2.1
2.1
—
—
—
0
0
7
95
0.73
0.22
1.3
1.5
—
—
—
0
0
8
102
0.78
0.21
1.4
2.9
—
—
—
0
0
58
624
0.92
0.20
3.4
4.3
4.98
31.31
ug/l
1.33
49
531
0
14
0.00
0.20
0.0
4.8
—
48.00
—
0
14
17
147
1.16
0.18
1.5
1.5
370.41
285.67
mu/l
0.64
17
136
7
59
1.19
0.18
1.7
1.3
—
—
—
0
0
27
243
1.12
0.17
1.8
1.8
—
—
—
0
0
8
71
1.13
0.16
1.4
1.2
—
—
—
0
0
8
73
1.10
0.15
1.8
2.3
—
—
—
0
0
6
77
0.78
0.15
1.2
1.6
—
—
—
0
0
45
420
1.08
0.15
1.3
1.4
—
—
—
0
0
7
86
0.81
0.14
1.3
1.5
—
—
—
0
0
16
141
1.14
0.14
1.6
1.4
12.91
8.03
u/l
—
10
115
13
113
1.15
0.13
1.2
1.2
4.20
3.73
mmol/l
0.57
13
103
16
142
1.13
0.12
3.3
2.6
—
—
—
0
0
12
137
0.87
0.12
1.3
1.1
—
—
—
0
0
5
48
1.04
0.09
1.4
1.2
—
—
—
0
0
15
136
1.11
0.08
3.0
2.7
—
—
—
0
0
23
214
1.08
0.08
1.8
2.1
—
—
—
0
0
6
58
1.03
0.08
1.2
1.3
—
—
—
0
0
6
58
1.03
0.08
1.0
1.3
—
—
nmol/l
—
0
0
7
67
1.05
0.08
1.1
1.1
—
—
—
0
0
6
72
0.83
0.07
1.2
1.2
—
—
—
0
0
7
83
0.84
0.07
1.3
1.4
—
—
—
0
0
7
83
0.84
0.07
1.3
1.5
—
—
—
0
0
7
84
0.83
0.07
3.3
3.2
369.57
19.80
u/ml
—
7
84
23
217
1.06
0.06
1.8
2.1
—
—
—
0
0
23
217
1.06
0.06
1.8
1.9
—
—
—
0
0
23
218
1.06
0.05
1.9
2.1
—
—
—
0
0
24
230
1.04
0.03
1.0
1.1
—
—
—
0
0
10
108
0.92
0.03
1.6
2.8
—
—
—
0
0
10
94
1.06
0.01
2.9
2.9
—
—
—
0
0
16
166
0.96
0.00
2.2
2.2
—
—
—
0
0
13
129
1.01
0.00
1.2
1.3
518.54
439.77
mg/l
0.55
13
120
0
8
0.00
0.00
0.0
1.0
—
19.21
—
0
8
0
8
0.00
0.00
0.0
1.7
—
—
—
0
0
51
510
1.00
-0.00
4.7
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
6.25
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
39.14
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.6
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
8363.00
—
0
9
6
63
0.95
-0.00
1.2
1.3
0.65
0.57
nmol/l
—
6
57
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.94
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
15.12
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint H7_VASCCILIARY and mortality.

Females

Parameter HR [95% CI] p-value
H7_VASCCILIARY 1.43 [1.22, 1.67] < 0.001
Birth year 0.998 [0.99, 1.01] 0.646

During the follow-up period (1.1.1998 — 31.12.2019), 674 out of 2047 females with H7_VASCCILIARY died.

Males

Parameter HR [95% CI] p-value
H7_VASCCILIARY 1.647 [1.36, 1.99] < 0.001
Birth year 0.986 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 628 out of 2837 males with H7_VASCCILIARY died.

Mortality risk

Mortality risk for people of age

years, who have H7_VASCCILIARY.

N-year risk Females Males
1 0.142% 0.259%
5 0.861% 1.779%
10 2.386% 4.403%
15 4.604% 8.327%
20 8.298% 13.714%

Relationships between endpoints

↥

Index endpoint: H7_VASCCILIARY – Hyphaema and other vascular disorders of iris and ciliary body

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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