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Hyphaema and other vascular disorders of iris and ciliary body

DOID EFO Endpoint Browser PheWeb

H7_VASCCILIARY

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H21.0, H21.1
  • Hospital discharge: ICD-9 — 3644
  • Cause of death: ICD-10 — H21.0, H21.1
  • Cause of death: ICD-9 — 3644

2 out of 7 registries used, show all original rules.

693

4. Check minimum number of events

None

693

5. Include endpoints

None

693

6. Filter based on genotype QC (FinnGen only)

693

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5991 2454 3510
Only index persons 5469 2239 3230
Unadjusted period prevalence (%)
Whole population 0.09 0.07 0.10
Only index persons 0.11 0.08 0.12
Median age at first event (years)
Whole population 60.60 71.92 52.62
Only index persons 59.68 71.26 51.65

-FinnGen-

Key figures

All Female Male
Number of individuals 693 301 392
Unadjusted period prevalence (%) 0.14 0.10 0.17
Median age at first event (years) 65.10 65.44 64.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
616
Matched controls
6160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H21.0
ICD-10 Finland
Hyphaema
+∞
323.0
422
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
227.6
204
*
S01ED51
ATC
timolol, combinations; ophthalmic
24.5
199.9
305
237
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
108.0
132.9
142
17
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
1454.3
125.6
118
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
31.8
108.1
145
59
H43.1
ICD-10 Finland
Vitreous haemorrhage
34.2
105.8
139
52
S01EC01
ATC
acetazolamide; systemic
29.1
94.8
130
56
114
Kela drug reimbursment
Glaucoma
9.9
91.1
204
294
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
87.6
82
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.4
83.8
387
1458
CKC12
NOMESCO Finland
Photocoagulation of retina
17.4
82.0
134
97
WX140
NOMESCO Finland
Parabulbar anesthesy
14.0
81.5
147
135
S01EE01
ATC
latanoprost; ophthalmic
11.2
80.1
163
192
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.9
78.9
232
495
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
11.8
70.1
137
146
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.9
66.1
187
366
S01EA03
ATC
apraclonidine; ophthalmic
55.0
61.8
73
15
S01ED01
ATC
timolol; ophthalmic
12.3
60.2
114
112
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
221.1
59.2
60
*
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
28.6
58.6
80
32
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.4
57.2
150
258
XCK10
NOMESCO Finland
Photography of fundus of eye
6.3
55.0
165
340
S01EC04
ATC
brinzolamide; ophthalmic
11.3
49.6
97
100
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.6
48.6
318
1396
H3603, E113
ICD-10 Finland
NA
39.8
46.3
58
16
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
64.2
46.1
53
9
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
14.2
45.9
80
64
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.6
45.9
189
544
H16.0
ICD-10 Finland
Corneal ulcer
22.5
44.6
65
32
CKC15
NOMESCO Finland
Panretinal photocoagulation
37.6
43.3
55
16
CKC20
NOMESCO Finland
Cryopexy of undetached retina
97.0
41.4
45
5
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
40.2
331
1648
XCK00
NOMESCO Finland
Perimetry
6.6
39.8
110
197
CKD40
NOMESCO Finland
Endophotocoagulation of retina
17.0
39.2
63
41
S01EC54
ATC
brinzolamide, combinations; ophthalmic
21.5
37.3
55
28
H3603, E103
ICD-10 Finland
NA
34.6
37.2
48
15
S01EC03
ATC
dorzolamide; ophthalmic
16.7
34.1
55
36
H40.0
ICD-10 Finland
Glaucoma suspect
5.8
33.8
103
207
S01EE03
ATC
bimatoprost; ophthalmic
12.0
33.3
62
57
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
26.0
33.2
46
19
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.4
32.6
91
163
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
11.8
32.0
60
56
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
328.7
31.1
31
*
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
8.6
30.3
68
88
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
112.3
29.9
32
*
A10AE04
ATC
insulin glargine; parenteral
4.4
29.9
120
323
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.8
29.7
108
263
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.4
28.3
111
291
H25.1
ICD-10 Finland
Senile nuclear cataract
2.8
28.2
240
1140
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
8.9
28.1
61
75
H34.8
ICD-10 Finland
Other retinal vascular occlusions
11.0
27.5
53
52
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
8.1
26.9
62
84
CKC10
NOMESCO Finland
Local photocoagulation of retina
11.2
26.8
51
49
XCH00
NOMESCO Finland
Eye pressure measurement
6.9
26.3
68
109
A10AA02
ATC
NA
7.6
26.2
63
91
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
42.1
26.1
32
8
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
15.3
26.1
43
30
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
15.3
26.1
43
30
XCD10
NOMESCO Finland
Electrophysiological examination of eye
9.3
25.6
54
63
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.8
25.2
119
368
S01BC03
ATC
diclofenac; ophthalmic
11.5
25.0
47
44
WX002
NOMESCO Finland
Sedation and analgesia
2.9
24.9
178
747
H26.4
ICD-10 Finland
After-cataract
3.8
24.8
116
355
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.4
24.7
95
243
H26.2
ICD-10 Finland
Complicated cataract
19.6
24.6
37
20
CKD15
NOMESCO Finland
Injection of vitreous substitute
50.6
24.5
29
6
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.1
24.5
49
52
A10AA01
ATC
NA
9.1
23.0
49
58
ZXA00
NOMESCO Finland
Right side
2.6
23.0
218
1075
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
14.4
22.6
38
28
H33.0
ICD-10 Finland
Retinal detachment with retinal break
7.3
22.4
55
82
CHC05
NOMESCO Finland
Iridotomy
13.4
21.9
38
30
T89
ICPC
Diabetes insulin dependent
6.9
21.7
55
86
H40.9
ICD-10 Finland
Glaucoma, unspecified
12.2
21.5
39
34
S01BC05
ATC
ketorolac; ophthalmic
5.5
21.0
64
127
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
7.6
20.7
49
69
CKD20
NOMESCO Finland
Removal of vitreous body substitute
28.1
20.2
27
10
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
19.6
20.1
30
16
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
19.9
19
*
S01EX03
ATC
NA
7.3
19.9
48
70
S01EE05
ATC
tafluprost; ophthalmic
7.0
19.6
49
75
ZXA10
NOMESCO Finland
Bilateral
2.7
19.6
156
687
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
13.9
19.4
33
25
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
6.7
19.4
50
80
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
15.5
19.1
31
21
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
5.2
18.8
60
126
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
8.1
18.7
42
55
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
195.7
18.6
19
*
H3601, E113
ICD-10 Finland
NA
8.5
18.3
40
50
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
34.0
18.1
23
7
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
17.2
18.0
28
17
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
68.7
17.8
20
*
XCD20
NOMESCO Finland
Photoangiography of eye
10.0
17.6
35
37
S01EE04
ATC
travoprost; ophthalmic
8.3
17.6
39
50
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
13.1
17.3
30
24
H3601, E103
ICD-10 Finland
NA
15.6
16.8
27
18
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.9
16.7
71
198
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
9.9
16.6
33
35
H36.01
ICD-10 Finland
Diabetic maculopathy
10.2
16.3
32
33
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
31.0
16.2
21
7
ZXA05
NOMESCO Finland
Left side
2.2
16.2
197
1068
S01FA04
ATC
cyclopentolate; ophthalmic
19.2
16.1
24
13
S05.9
ICD-10 Finland
Injury of eye and orbit, unspecified
25.3
16.1
22
9
A10AE05
ATC
insulin detemir; parenteral
3.9
15.7
66
182
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
13.5
15.3
26
20
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
6.3
15.1
40
67
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.9
14.9
62
170
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
25.8
14.8
20
8
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
8.4
14.7
32
40
WX142
NOMESCO Finland
Sub-tenon anesthesy
17.5
14.4
22
13
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
22.9
14.3
20
9
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.9
14.2
92
349
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
30.8
13.9
18
6
S01FA02
ATC
scopolamine; ophthalmic
18.1
13.9
21
12
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
13.6
49
117
CG2S4
NOMESCO Finland
Photography of cornea
143.0
13.5
14
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
143.0
13.5
14
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.6
13.5
47
109
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.4
13.4
29
36
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.6
13.4
34
54
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
13.4
195
1125
H26.02
ICD-10 Finland
Presenil cataract
7.1
13.3
32
47
NHQ40
NOMESCO Finland
Amputation of toe
7.8
13.3
30
40
H04AA01
ATC
glucagon; nasal, parenteral
7.0
13.1
32
48
H16.9
ICD-10 Finland
Keratitis, unspecified
132.6
12.5
13
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
38.4
12.3
15
*
H26.3
ICD-10 Finland
Drug-induced cataract
27.3
12.1
16
6
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
12.0
69
243
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.0
11.9
21
18
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
4.7
11.9
40
90
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.9
11.7
26
34
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
66.2
11.6
13
*
H3600, E103
ICD-10 Finland
NA
11.4
11.6
21
19
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
11.5
11
*
3644A
ICD-9 Finland
Disorders of iris and ciliary body, Vascular disorders of iris and ciliary body
+∞
11.5
11
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
5.2
11.4
35
71
L04AB04
ATC
adalimumab; parenteral
10.8
11.3
21
20
H57.1
ICD-10 Finland
Ocular pain
6.3
11.2
29
48
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
11.2
165
946
L04AA01
ATC
[U] ciclosporin; systemic
8.8
11.1
23
27
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
10.3
11.1
21
21
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.3
11.1
21
21
CS494
NOMESCO Finland
Other visual field testing
6.2
11.0
29
49
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
10.9
63
223
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
10.9
51
155
H53.1
ICD-10 Finland
Subjective visual disturbances
3.3
10.9
54
172
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
6.9
10.8
26
39
H27.1
ICD-10 Finland
Dislocation of lens
18.2
10.8
16
9
H3600, E113
ICD-10 Finland
NA
7.8
10.8
24
32
J01FF01
ATC
clindamycin; systemic
2.0
10.7
172
1017
C03CA01
ATC
furosemide; systemic
1.9
10.6
214
1373
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
5.2
10.6
32
64
ZX198
NOMESCO Finland
Other local administration
10.3
10.6
20
20
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
7.3
10.4
24
34
TK800
NOMESCO Finland
Hemodialysis
5.8
10.2
28
50
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.4
10.0
48
149
CG2T4
NOMESCO Finland
Topography assessment of cornea
40.8
10.0
12
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.8
9.8
19
20
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.6
9.8
22
30
S01FA01
ATC
atropine; ophthalmic
13.6
9.7
16
12
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.3
9.7
49
159
L04AD01
ATC
ciclosporin; systemic
8.6
9.6
20
24
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.9
9.6
60
224
H30.2
ICD-10 Finland
Posterior cyclitis
101.5
9.4
10
*
H18.8
ICD-10 Finland
Other specified disorders of cornea
101.5
9.4
10
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
9.4
162
977
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
+∞
9.4
9
*
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
9.4
9
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
9.4
9
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
9.4
200
1298
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
5.2
9.4
28
56
CHD00
NOMESCO Finland
Laser trabeculoplasty
7.5
9.3
21
29
A10AE06
ATC
insulin degludec; parenteral
4.9
9.3
29
61
SPAT1262
SPAT
Handing over of treatment supplies
2.1
9.2
120
650
C08CA01
ATC
amlodipine; oral
1.7
9.1
227
1543
CKD60
NOMESCO Finland
Anterior vitrectomy
9.2
9.1
18
20
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.0
9.1
35
91
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.7
9.0
22
34
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.9
9.0
24
42
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.9
9.0
28
59
XCH05
NOMESCO Finland
Eye pressure longterm registration
12.8
8.9
15
12
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
8.9
110
584
H34.1
ICD-10 Finland
Central retinal artery occlusion
9.7
8.8
17
18
CHD99
NOMESCO Finland
Other filtering operation
14.3
8.7
14
10
C10AA05
ATC
atorvastatin; oral
1.7
8.6
233
1617
L04AB06
ATC
golimumab; parenteral
16.6
8.6
13
8
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
16.6
8.6
13
8
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
8.6
73
326
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.9
8.6
34
91
H54.4
ICD-10 Finland
Blindness, monocular
27.9
8.5
11
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
20.4
8.5
12
6
H26.1
ICD-10 Finland
Traumatic cataract
20.4
8.5
12
6
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.6
8.5
28
63
H3603, E107
ICD-10 Finland
NA
91.2
8.4
9
*
Z94.7
ICD-10 Finland
Corneal transplant status
91.2
8.4
9
*
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
6.0
8.4
22
38
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.1
8.3
25
51
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
11.9
8.1
14
12
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
17.4
8.1
12
7
B03XA02
ATC
darbepoetin alfa; parenteral
5.4
8.1
23
44
AA1AD
NOMESCO Finland
CT of head and brain
1.8
8.0
152
941
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
8.0
100
533
N18.0
ICD-10 Finland
End-stage renal disease
7.9
7.9
17
22
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.2
7.9
13
10
A11CC03
ATC
alfacalcidol; systemic
4.8
7.9
25
54
A02BC02
ATC
pantoprazole; systemic
1.6
7.9
375
3009
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
8.6
7.8
16
19
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
7.8
73
341
C07AB07
ATC
bisoprolol; oral
1.6
7.8
287
2150
L04AB05
ATC
certolizumab pegol; parenteral
45.6
7.7
9
*
127
Kela drug reimbursment
Transplant complication
7.6
7.7
17
23
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
7.6
7.7
17
23
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.2
7.6
16
20
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.2
7.6
39
129
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
10.2
7.6
14
14
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
81.0
7.4
8
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
5.7
7.4
20
36
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.8
7.4
16
21
H40.8
ICD-10 Finland
Other glaucoma
13.6
7.4
12
9
I50.0
ICD-10 Finland
Congestive heart failure
2.4
7.4
65
294
S01AD03
ATC
aciclovir; ophthalmic
4.3
7.4
26
63
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
7.4
62
273
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
7.3
50
198
L04AA06
ATC
mycophenolic acid; systemic
5.9
7.3
19
33
H25.8
ICD-10 Finland
Other senile cataract
2.1
7.2
82
417
B01AC04
ATC
clopidogrel; oral
1.9
7.2
110
630
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.4
7.1
20
38
1LA05
NOMESCO Finland
NA
12.2
7.1
12
10
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.4
6.9
57
252
H54.1
ICD-10 Finland
Severe visual impairment, binocular
40.5
6.8
8
*
CA1AD
NOMESCO Finland
Orbita CT
40.5
6.8
8
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
40.5
6.8
8
*
L04AA17
ATC
[U] adalimumab; parenteral
16.9
6.8
10
6
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
16.9
6.8
10
6
C09AA02
ATC
enalapril; systemic
1.8
6.7
132
820
H44.5
ICD-10 Finland
Degenerated conditions of globe
22.8
6.7
9
*
CKD50
NOMESCO Finland
Endodiathermy of retina
22.8
6.7
9
*
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
6.0
6.6
17
29
H35.6
ICD-10 Finland
Retinal haemorrhage
12.4
6.6
11
9
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
8.8
6.6
13
15
Z94.0
ICD-10 Finland
Kidney transplant status
8.8
6.6
13
15
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
10.2
6.6
12
12
A10AA03
ATC
NA
7.0
6.5
15
22
SPAT1009
SPAT
Measurement of intraocular pressure
7.0
6.5
15
22
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.0
6.4
24
62
H40
ICD-10 Finland
Glaucoma
7.5
6.4
14
19
CH2S4
NOMESCO Finland
Photography of iris
70.5
6.4
7
*
S18
ICPC
Laceration/cut
1.6
6.4
236
1744
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.4
494
4358
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
14.5
6.4
10
7
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.4
335
2691
M45
ICD-10 Finland
Ankylosing spondylitis
5.3
6.4
18
35
V03AE01
ATC
polystyrene sulfonate; oral
5.6
6.3
17
31
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
4.7
6.3
20
44
Z49.2
ICD-10 Finland
Other dialysis
11.2
6.3
11
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
6.3
50
215
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.3
183
1274
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
6.3
6
*
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
+∞
6.3
6
*
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
6.3
6
*
H221, M084
ICD-10 Finland
NA
+∞
6.3
6
*
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
6.3
6
*
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
6.3
6
*
H18.6
ICD-10 Finland
Keratoconus
+∞
6.3
6
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
27.0
6.2
8
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
27.0
6.2
8
*
N18.8
ICD-10 Finland
Other chronic renal failure
3.6
6.2
26
75
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
6.1
135
870
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
6.8
6.1
14
21
A12AA04
ATC
calcium carbonate; oral
5.6
6.0
16
29
S01ED02
ATC
betaxolol; ophthalmic
5.6
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
143
647
2.52
19.61
2.4
1.6
—
—
—
0
0
93
401
2.52
13.87
7.1
3.6
134.3
86.0
ng/l
2.71
82
352
135
689
2.19
13.68
15.2
5.4
1.1
1.0
mmol/l
4.04
127
629
259
1673
1.88
13.49
5.0
3.2
6.6
7.7
mmol/l
2.99
218
1396
145
767
2.13
13.40
5.3
2.3
21.0
22.4
%
0.66
124
659
245
1570
1.87
12.99
5.2
3.3
677.4
365.6
mg/l
0.42
174
1028
324
2270
1.80
12.78
12.5
9.6
1.2
1.3
inr
0.60
78
666
69
267
2.76
12.76
1.8
2.0
1.8
1.5
g/l
1.41
60
234
253
1658
1.83
12.35
6.1
4.0
21.6
10.2
mg/mmol
1.78
174
1074
261
1731
1.81
12.22
7.8
5.6
—
—
—
0
0
147
807
2.04
12.21
5.1
2.3
2.1
2.3
g/l
3.93
132
740
155
871
2.00
12.05
5.0
2.3
11.3
12.8
umol/l
1.92
142
804
66
259
2.71
11.87
8.2
3.8
23.2
24.0
mmol/l
1.47
59
234
150
844
1.99
11.58
3.6
3.4
0.8
0.8
mmol/l
0.02
145
783
125
661
2.09
11.44
3.3
2.7
1.7
1.8
%
0.22
110
596
309
2201
1.73
11.01
2.4
2.0
86.4
95.2
pmol/l
2.54
171
1152
327
2389
1.70
10.45
8.3
5.7
0.7
0.7
%
0.34
307
2245
360
2700
1.69
10.41
8.0
5.8
0.2
0.2
e9/l
0.66
321
2390
37
112
3.43
10.40
4.5
2.6
—
—
—
0
0
334
2457
1.69
10.38
7.9
5.6
2.8
2.9
%
0.14
314
2309
358
2684
1.69
10.35
7.9
5.6
1.8
1.9
e9/l
1.09
316
2380
350
2611
1.69
10.29
7.8
5.5
0.6
0.6
e9/l
1.06
313
2278
351
2625
1.68
10.18
7.8
5.5
0.0
0.0
e9/l
0.07
312
2299
33
94
3.64
10.16
1.8
1.4
109.3
104.4
u/ml
0.16
11
18
408
3176
1.69
10.15
7.8
4.8
7.6
6.7
mmol/l
7.12
390
2972
174
1070
1.84
10.13
2.0
1.7
1153.4
1184.5
nmol/l
0.14
143
808
334
2470
1.68
10.08
8.5
5.9
8.8
8.7
%
0.16
315
2334
332
2456
1.68
9.97
11.5
5.8
1.2
1.2
mmol/l
1.28
302
2206
475
3868
1.72
9.84
5.4
4.0
16.3
12.6
mm/h
4.18
444
3560
231
1555
1.73
9.83
6.1
4.2
—
—
—
0
0
338
2529
1.66
9.59
8.4
5.8
25.6
27.3
%
2.08
317
2374
11
11
10.15
9.56
5.2
3.5
—
—
—
0
0
239
1635
1.70
9.54
2.4
2.1
249.2
259.9
u/l
0.06
226
1538
91
457
2.14
9.46
12.9
7.6
—
—
—
0
0
333
2498
1.64
9.24
8.1
5.5
58.2
57.7
%
0.35
314
2362
101
533
2.05
9.21
8.6
3.6
1.0
1.9
mmol/l
1.44
88
416
34
106
3.32
9.15
2.0
1.4
—
—
—
0
0
22
51
4.42
8.92
1.0
1.2
—
—
—
0
0
111
616
1.95
8.77
1.5
1.3
554.3
462.6
titre
0.27
28
122
137
816
1.85
8.72
3.0
2.1
—
—
—
0
0
207
1398
1.69
8.50
3.0
2.1
3.2
3.2
mg/l
0.07
180
1184
349
2685
1.60
8.48
13.6
6.5
1.2
1.2
mmol/l
1.13
305
2239
328
2493
1.60
8.34
5.9
4.1
—
—
—
0
0
48
193
2.60
8.25
2.8
2.3
893.6
412.8
ug/l
0.58
48
182
232
1629
1.64
8.13
8.6
4.0
7.4
7.4
ph
1.91
39
306
310
2337
1.59
8.08
7.9
4.7
34.1
35.3
g/l
3.64
289
2162
237
1702
1.60
7.44
3.9
2.5
—
—
—
0
0
90
491
1.96
7.44
4.0
2.7
65.4
69.0
e9/l
0.37
68
399
429
3533
1.56
7.29
6.5
4.7
838.9
4043.1
e6/l
—
9
57
444
3690
1.57
7.21
6.3
4.3
—
—
—
0
0
198
1372
1.62
7.17
3.3
2.7
375.4
6798.8
umol/l
5.47
168
1183
379
3055
1.53
6.96
9.8
8.8
4.3
4.2
e9/l
0.32
337
2700
21
57
3.77
6.96
2.5
2.5
—
—
—
0
0
593
5313
1.80
6.94
24.7
14.9
24.2
25.3
mg/l
0.41
495
4231
30
103
3.00
6.93
1.3
1.2
282.5
216.3
u/ml
0.77
22
59
11
17
6.56
6.79
1.9
1.7
—
—
—
0
0
290
2217
1.53
6.75
4.9
2.7
151.3
143.2
ug/l
0.25
269
2023
116
708
1.77
6.72
8.5
6.4
104.1
104.1
mmol/l
0.02
116
690
20
55
3.71
6.51
1.3
1.2
—
—
—
0
0
108
653
1.77
6.45
7.6
6.9
0.3
1.3
mmol/l
1.36
92
498
183
1277
1.59
6.33
4.2
2.4
—
—
—
0
0
50
234
2.23
6.20
1.3
1.5
—
13.6
—
0
6
242
1815
1.51
6.00
4.0
3.3
2.3
2.3
mmol/l
0.34
207
1579
227
1686
1.52
5.87
3.7
3.2
3193.8
1633.1
ng/l
1.70
201
1441
474
4084
1.51
5.81
9.9
7.5
83.5
79.5
u/l
0.99
454
3822
156
1069
1.59
5.77
1.4
1.2
0.8
1.8
u/ml
1.58
41
286
79
452
1.84
5.65
1.8
3.3
66.8
66.5
g/l
0.09
72
408
25
89
2.88
5.46
7.2
2.6
—
—
—
0
0
533
4736
1.54
5.40
5.3
4.5
5.7
2.2
mu/l
0.47
486
4290
117
759
1.65
5.38
37.4
25.9
1.2
1.3
inr
—
10
99
342
2797
1.44
5.26
6.3
6.3
12.2
11.7
umol/l
0.20
326
2645
182
1316
1.52
5.26
1.8
1.6
17.9
20.6
nmol/l
1.92
156
1108
35
151
2.39
5.25
1.7
1.5
207.3
279.2
ug/g
1.38
23
90
26
97
2.75
5.22
5.0
2.3
70.9
61.8
%
1.19
26
97
541
4836
1.54
5.20
8.9
5.9
45.5
40.1
mmol/mol
12.76
500
4462
18
54
3.40
5.19
1.3
1.2
—
—
—
0
0
594
5433
1.65
5.10
30.2
17.5
139.4
139.6
mmol/l
1.11
584
5287
54
282
1.99
5.08
1.6
1.3
—
—
—
0
0
88
540
1.72
4.98
8.7
7.5
116.6
121.5
g/l
1.48
88
520
94
588
1.69
4.96
2.4
1.6
—
—
—
0
0
594
5444
1.64
4.92
31.0
17.7
4.0
4.0
mmol/l
1.97
584
5291
219
1665
1.46
4.89
4.4
3.3
—
—
—
0
0
66
375
1.84
4.84
1.9
2.9
—
—
—
0
0
275
2185
1.43
4.84
4.8
3.8
48.0
44.6
ng/l
0.16
210
1566
31
132
2.41
4.80
1.8
4.5
—
—
—
0
0
8
7
11.54
4.79
20.8
3.0
5.7
7.5
mmol/l
—
8
7
38
178
2.20
4.75
2.0
4.3
40.9
34.7
mg/l
0.41
31
146
38
178
2.20
4.75
2.0
4.3
67.0
98.3
mg/l
0.40
32
146
137
955
1.54
4.64
1.4
1.5
2.5
2.5
g/l
0.06
83
580
64
366
1.82
4.60
4.7
3.6
7.4
7.4
ph
—
6
38
66
383
1.80
4.53
4.0
4.2
0.4
0.5
%
0.24
13
105
44
223
2.04
4.51
5.5
4.3
24.6
25.0
mmol/l
0.49
39
210
72
430
1.75
4.49
4.5
4.2
0.9
0.9
%
0.00
19
141
69
408
1.77
4.45
4.4
4.5
—
—
—
0
0
572
5229
1.54
4.43
5.8
4.9
2.5
2.7
mmol/l
3.91
530
4774
80
495
1.70
4.40
2.6
2.4
5.2
7.4
ug/l
1.17
67
436
218
1686
1.43
4.36
4.4
2.5
55.2
56.6
u/l
0.15
200
1576
30
132
2.33
4.35
1.4
1.2
80.0
78.5
titre
—
5
13
76
467
1.70
4.29
2.0
1.9
343.9
381.9
nmol/l
1.24
71
431
440
3848
1.39
4.18
4.3
3.8
15.1
14.9
pmol/l
1.27
403
3455
9
13
7.00
4.17
1.1
1.0
—
—
—
0
0
93
609
1.61
4.11
3.0
2.8
10.4
9.2
umol/l
0.18
81
531
10
23
4.40
4.10
2.8
2.3
—
—
—
0
0
67
403
1.73
4.08
4.0
4.3
0.2
0.1
%
0.10
18
128
147
1070
1.47
4.02
5.3
4.0
167.5
264.9
ng/l
0.77
128
859
94
623
1.59
3.95
1.8
1.4
—
—
—
0
0
125
887
1.50
3.87
2.5
1.9
—
—
—
0
0
104
715
1.53
3.73
2.4
1.6
—
—
—
0
0
554
5086
1.45
3.67
5.2
4.3
1.4
1.4
mmol/l
1.64
515
4651
171
1304
1.41
3.62
6.5
6.6
—
—
—
0
0
34
171
2.04
3.60
1.3
1.2
—
—
—
0
0
20
80
2.54
3.57
1.1
1.1
—
—
—
0
0
603
5638
1.54
3.55
14.1
10.3
26.3
26.5
u/l
0.08
590
5431
422
3717
1.35
3.53
4.7
4.0
—
—
—
0
0
111
784
1.50
3.51
1.3
1.2
32.8
37.5
iu/ml
0.20
34
234
19
75
2.58
3.49
7.1
5.6
12.4
11.5
mg/l
0.38
19
68
278
2306
1.34
3.47
13.2
9.6
0.0
0.0
e9/l
0.44
234
1906
32
161
2.04
3.40
2.3
3.0
35.0
37.6
g/l
1.34
27
139
62
385
1.67
3.39
3.6
4.3
0.1
0.9
%
0.55
13
112
549
5057
1.41
3.35
5.3
4.5
6.5
6.0
mmol/l
5.98
497
4558
310
2623
1.33
3.35
4.9
3.8
0.0
0.0
estimate
0.50
48
497
555
5124
1.42
3.32
5.2
4.3
4.3
4.6
mmol/l
4.44
514
4720
306
2587
1.33
3.31
6.4
5.1
0.0
0.0
estimate
0.00
53
519
189
1486
1.37
3.31
4.4
3.1
—
—
—
0
0
32
163
2.01
3.29
5.7
3.4
—
—
—
0
0
66
421
1.63
3.26
1.7
1.7
—
—
—
0
0
9
19
4.78
3.24
1.0
1.3
—
—
—
0
0
41
229
1.84
3.23
1.4
1.2
—
—
—
0
0
8
15
5.38
3.20
1.0
1.1
—
—
—
0
0
119
871
1.44
3.14
3.6
3.1
1.8
2.0
e6/l
0.14
66
491
305
2594
1.31
3.11
4.8
3.8
0.0
0.0
estimate
0.00
52
519
533
4906
1.37
3.10
4.7
3.9
1.3
1.3
mmol/l
0.47
492
4460
15
56
2.72
3.07
4.1
2.7
—
—
—
0
0
49
294
1.72
3.06
12.1
9.4
—
—
—
0
0
8
16
5.04
3.05
1.0
1.0
—
—
—
0
0
153
1179
1.38
3.01
5.5
3.9
—
—
—
0
0
9
21
4.33
3.00
1.0
1.0
1014.8
1365.1
miu/ml
—
9
21
46
274
1.73
2.95
5.0
3.6
—
—
—
0
0
21
95
2.25
2.92
1.2
1.2
—
—
—
0
0
69
458
1.56
2.91
5.0
3.6
—
—
—
0
0
22
102
2.19
2.89
11.9
1.8
0.8
0.8
nmol/l
0.08
17
86
208
1690
1.33
2.89
4.9
3.4
63.1
107.9
e6/l
0.47
166
1304
12
41
2.96
2.87
1.9
1.6
9.0
10.6
%
0.56
12
41
29
152
1.95
2.79
2.9
2.5
260.2
75.8
ug/min
0.55
16
91
622
5912
1.51
2.76
35.7
21.5
91.1
91.1
fl
0.09
616
5817
622
5912
1.51
2.76
35.7
21.4
30.2
30.3
pg
1.32
616
5817
622
5913
1.51
2.75
35.9
21.5
4.4
4.5
e12/l
4.40
609
5735
622
5913
1.51
2.75
35.9
21.6
6.9
6.8
e9/l
0.94
610
5734
56
359
1.61
2.74
1.3
1.2
—
—
—
0
0
622
5914
1.51
2.73
36.1
21.7
131.8
135.8
g/l
6.95
615
5815
37
212
1.79
2.72
1.1
1.1
—
95.9
—
0
7
146
1134
1.36
2.72
1.6
1.7
1.1
1.2
mg/l
0.55
110
859
233
1940
1.30
2.69
5.8
3.8
58.5
137.9
e6/l
1.06
181
1388
621
5908
1.49
2.66
35.9
21.6
245.2
243.9
e9/l
0.18
609
5748
149
1172
1.35
2.55
5.6
4.3
1.0
1.0
kg/l
0.28
22
170
22
108
2.07
2.54
2.5
2.1
121.1
126.6
g/l
0.40
14
81
188
1543
1.30
2.38
4.5
3.2
0.2
0.6
e6/l
2.95
143
1162
23
118
1.98
2.38
4.7
3.6
—
—
—
0
0
21
105
2.03
2.33
1.2
1.2
44.7
34.6
u/l
0.19
16
92
477
4391
1.28
2.31
30.1
18.1
14.0
13.7
%
3.44
470
4307
8
23
3.51
2.27
3.5
20.4
—
—
—
0
0
17
80
2.15
2.20
1.1
1.0
—
—
—
0
0
42
267
1.61
2.17
1.9
3.3
4.1
4.5
pmol/l
1.71
36
232
37
228
1.66
2.16
6.8
4.6
—
—
—
0
0
583
5530
1.34
2.13
23.7
14.0
—
—
—
0
0
10
37
2.73
2.11
4.8
2.8
—
—
—
0
0
29
169
1.75
2.07
18.4
11.4
—
—
—
0
0
71
512
1.43
2.06
9.6
4.3
—
—
—
0
0
164
1350
1.28
2.01
1.6
1.6
1.5
1.4
mmol/l
0.58
143
1124
132
1056
1.31
2.01
3.8
3.1
2.5
2.5
mmol/l
0.74
115
927
147
1196
1.29
1.97
4.3
2.6
5.1
4.7
e6/l
0.16
136
1043
14
64
2.21
1.95
1.1
1.3
—
—
—
0
0
21
114
1.87
1.89
2.6
1.8
5.2
7.3
iu/l
—
9
35
7
22
3.20
1.88
4.0
1.5
0.1
0.1
e9/l
—
7
22
28
168
1.69
1.83
1.3
1.2
1.1
2.2
u/ml
—
6
13
7
23
3.06
1.80
1.0
1.1
—
—
—
0
0
13
60
2.19
1.78
3.0
1.3
54.3
51.4
mu/l
0.04
13
55
77
579
1.37
1.78
2.0
2.3
255.0
122.7
ug/g
0.85
65
455
20
110
1.84
1.74
3.0
2.3
15.3
16.0
%
0.24
11
55
5
13
3.87
1.72
1.4
1.5
—
—
—
0
0
49
342
1.47
1.71
3.7
3.1
—
—
—
0
0
41
278
1.50
1.66
2.3
2.5
—
—
—
0
0
19
105
1.83
1.64
2.7
2.5
—
—
—
0
0
170
1439
1.24
1.63
5.7
4.1
0.0
0.0
estimate
0.69
51
496
73
553
1.36
1.63
1.2
1.3
—
—
—
0
0
138
1143
1.26
1.60
3.5
2.8
510.6
562.7
mosm/kgh2o
2.58
119
968
6
20
3.02
1.58
1.0
1.1
—
—
—
0
0
21
123
1.73
1.52
1.4
1.7
—
—
—
0
0
5
128
0.39
1.50
1.6
1.6
—
—
—
0
0
21
124
1.72
1.48
7.0
4.6
2.2
2.7
mmol/l
0.33
16
81
18
102
1.79
1.46
2.9
3.1
4.7
4.5
e9/l
0.16
18
102
7
28
2.51
1.45
3.7
1.6
—
—
—
0
0
11
52
2.13
1.45
2.5
3.9
63.5
52.8
%
—
6
39
136
1142
1.24
1.40
6.1
4.7
—
—
—
0
0
9
40
2.27
1.40
1.4
1.4
2.3
1.3
promille
—
9
32
509
4825
1.21
1.39
27.5
15.7
38.0
40.0
%
3.64
366
3376
7
29
2.43
1.39
3.9
3.8
76.0
107.8
nmol/l
—
7
29
7
29
2.43
1.39
3.3
1.7
—
—
—
0
0
42
300
1.43
1.35
1.1
1.2
195.7
135.3
iu/ml
0.29
15
116
18
105
1.73
1.34
3.5
3.4
62.4
59.8
%
0.39
18
105
9
42
2.16
1.34
1.2
1.5
—
—
—
0
0
85
682
1.28
1.30
1.3
1.2
—
—
—
0
0
20
125
1.62
1.18
2.9
4.2
18.2
29.4
mg/l
1.37
12
78
222
1985
1.17
1.17
2.2
2.1
—
—
—
0
0
51
387
1.34
1.17
1.7
1.4
—
—
—
0
0
52
398
1.33
1.13
2.4
2.6
11.4
10.6
g/l
0.50
46
358
11
58
1.91
1.12
4.8
4.8
—
—
—
0
0
91
753
1.24
1.10
1.3
1.3
4.7
9.1
u/ml
0.58
31
275
11
193
0.56
1.09
2.3
1.6
—
—
—
0
0
25
170
1.49
1.06
1.2
1.1
—
—
—
0
0
18
115
1.58
1.00
2.9
2.5
2444.8
3911.9
u/l
—
5
43
10
54
1.86
0.97
1.8
2.9
—
—
—
0
0
7
37
1.90
0.94
2.1
1.3
—
—
—
0
0
10
55
1.83
0.92
4.7
3.3
—
—
—
0
0
8
42
1.92
0.88
2.3
1.7
—
—
—
0
0
13
79
1.66
0.88
3.0
4.1
3.1
1.0
%
—
8
66
17
111
1.54
0.88
1.2
1.2
—
—
—
0
0
14
87
1.62
0.88
1.3
1.5
—
—
—
0
0
8
43
1.87
0.87
1.0
1.1
—
—
—
0
0
133
1169
1.17
0.87
1.9
1.7
434.9
17914029.9
pmol/l
1.04
111
949
55
444
1.26
0.85
1.3
1.4
—
—
—
0
0
22
154
1.44
0.84
1.2
1.1
—
—
—
0
0
159
1770
0.87
0.84
3.1
2.8
—
—
—
0
0
162
1454
1.15
0.81
3.8
3.4
—
—
—
0
0
228
2094
1.13
0.81
4.4
5.0
2.1
2.6
ug/l
0.95
193
1864
6
33
1.83
0.79
2.2
1.7
—
1940.0
—
0
5
0
26
0.00
0.78
0.0
1.0
—
15.5
—
0
5
32
243
1.33
0.78
2.8
2.8
—
—
—
0
0
18
123
1.48
0.78
2.9
1.8
155.9
233.8
pmol/l
3.39
18
116
5
99
0.50
0.78
1.8
1.4
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
2.4
—
0
8
28
211
1.34
0.73
4.5
3.6
0.4
0.3
g/l
0.49
18
88
5
25
2.01
0.73
1.0
1.2
150.6
145.7
nmol/l
—
5
25
9
56
1.61
0.72
1.2
1.2
—
—
—
0
0
40
498
0.79
0.72
1.5
1.7
—
—
—
0
0
11
68
1.63
0.72
1.4
1.2
—
—
—
0
0
43
348
1.25
0.68
4.1
2.9
4.5
4.0
e9/l
0.32
24
264
5
28
1.79
0.66
1.4
1.3
—
—
—
0
0
54
452
1.21
0.64
10.2
3.8
1.2
1.2
mmol/l
1.06
49
386
23
173
1.34
0.62
1.1
1.2
—
—
—
0
0
56
472
1.20
0.62
1.5
1.5
—
—
—
0
0
8
52
1.54
0.59
1.4
1.2
—
—
—
0
0
37
300
1.25
0.59
5.2
3.1
0.1
0.2
e6/l
2.23
37
292
11
72
1.54
0.59
1.4
1.1
—
—
—
0
0
6
37
1.63
0.55
1.3
1.0
—
—
—
0
0
154
1418
1.11
0.53
1.4
1.4
—
—
—
0
0
53
453
1.18
0.53
1.4
1.4
—
—
—
0
0
6
40
1.50
0.51
1.3
1.1
—
—
—
0
0
18
135
1.34
0.51
1.4
1.4
117.6
261.5
miu/ml
—
7
76
13
92
1.42
0.51
1.2
1.4
—
—
—
0
0
6
41
1.47
0.50
3.2
3.2
—
—
—
0
0
23
289
0.79
0.48
2.7
3.5
—
—
—
0
0
132
1212
1.11
0.48
2.6
3.0
0.7
0.8
ug/l
0.62
78
780
7
46
1.53
0.48
2.3
1.3
—
—
—
0
0
169
1572
1.10
0.48
5.1
4.0
—
—
—
0
0
14
103
1.37
0.45
2.4
1.6
—
—
—
0
0
14
103
1.37
0.45
1.4
1.5
—
—
—
0
0
7
51
1.38
0.44
2.3
2.4
—
—
—
0
0
38
446
0.84
0.43
1.3
1.4
—
—
—
0
0
21
167
1.27
0.42
1.8
1.6
—
—
—
0
0
8
57
1.41
0.42
1.1
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
14.3
—
0
7
32
273
1.18
0.35
1.4
1.3
253.7
201.4
u/ml
0.11
26
245
71
643
1.12
0.35
1.2
1.3
—
—
—
0
0
9
123
0.73
0.35
1.4
1.1
—
—
—
0
0
10
132
0.75
0.32
1.2
1.2
—
—
—
0
0
7
52
1.35
0.31
2.0
1.3
—
—
—
0
0
8
62
1.29
0.28
1.1
1.6
—
—
—
0
0
8
62
1.29
0.28
1.1
1.6
—
—
—
0
0
8
62
1.29
0.28
1.1
1.6
—
—
—
0
0
8
62
1.29
0.28
1.1
1.6
—
—
—
0
0
8
66
1.21
0.27
1.4
1.3
—
—
—
0
0
13
104
1.25
0.26
1.2
1.3
4.2
3.7
mmol/l
0.60
13
94
5
71
0.70
0.26
2.6
1.1
—
—
—
0
0
5
71
0.70
0.26
1.2
1.0
2.8
4.0
u/ml
—
5
35
5
72
0.69
0.26
2.6
1.1
—
—
—
0
0
5
74
0.67
0.26
1.2
1.0
14.3
8.6
u/ml
—
5
46
26
297
0.87
0.24
1.5
1.4
—
—
—
0
0
6
81
0.74
0.24
1.2
1.5
—
—
—
0
0
6
81
0.74
0.24
1.2
1.5
—
—
—
0
0
6
82
0.73
0.24
1.3
2.6
—
—
—
0
0
6
84
0.71
0.24
1.2
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
4.3
2.0
33.1
33.0
pg
—
10
80
0
14
0.00
0.20
0.0
4.8
—
48.0
—
0
14
0
14
0.00
0.20
0.0
1.1
—
2.8
—
0
7
0
14
0.00
0.20
0.0
1.1
—
2.3
—
0
14
15
127
1.19
0.19
3.0
2.5
—
—
—
0
0
16
186
0.86
0.19
2.2
1.8
—
—
—
0
0
7
60
1.17
0.18
1.6
1.4
—
—
—
0
0
16
138
1.16
0.17
1.5
1.5
387.6
281.9
mu/l
0.82
16
129
15
129
1.17
0.17
1.6
1.4
13.9
7.7
u/l
—
9
105
7
89
0.78
0.14
1.4
3.0
—
—
—
0
0
50
470
1.07
0.14
4.8
3.8
—
—
—
0
0
10
84
1.19
0.14
2.9
2.2
—
—
—
0
0
22
199
1.11
0.13
1.9
1.8
—
—
—
0
0
10
116
0.86
0.12
1.7
2.2
—
—
—
0
0
22
201
1.10
0.11
1.9
1.6
—
—
—
0
0
15
167
0.90
0.11
2.9
4.3
—
—
—
0
0
22
202
1.09
0.10
1.9
1.7
—
—
—
0
0
5
45
1.11
0.10
1.4
1.2
—
—
—
0
0
22
203
1.09
0.09
1.9
1.8
—
—
—
0
0
6
56
1.07
0.08
1.2
1.2
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
nmol/l
—
0
0
8
77
1.04
0.07
1.6
2.5
—
—
—
0
0
9
85
1.06
0.07
1.7
1.4
—
—
—
0
0
13
118
1.10
0.07
1.2
1.3
518.5
432.5
mg/l
0.61
13
109
22
206
1.07
0.07
1.0
1.1
—
—
—
0
0
49
472
1.04
0.07
2.7
2.1
13.0
13.5
nmol/l
0.18
38
423
31
297
1.05
0.05
1.3
1.2
—
—
—
0
0
21
221
0.95
0.04
1.6
1.9
—
—
—
0
0
55
563
0.97
0.04
3.5
4.2
5.2
33.3
ug/l
1.26
46
480
38
370
1.03
0.03
1.3
1.4
—
—
—
0
0
15
155
0.97
0.00
2.3
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
8363.0
—
0
9
5
53
0.94
0.00
1.0
1.2
—
—
—
0
0
7
75
0.93
0.00
3.3
2.8
369.3
17.4
u/ml
—
7
75
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
6
67
0.89
0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
65
0.92
0.00
2.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
19.2
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
6
62
0.97
0.00
1.2
1.2
0.7
0.6
nmol/l
—
6
56
6
63
0.95
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
6.8
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
79
0.88
0.00
1.3
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
39.1
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.2
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_VASCCILIARY and mortality.

Females

Parameter HR [95% CI] p-value
H7_VASCCILIARY 1.43 [1.22, 1.67] < 0.001
Birth year 0.998 [0.99, 1.01] 0.646

During the follow-up period (1.1.1998 — 31.12.2019), 674 out of 2047 females with H7_VASCCILIARY died.

Males

Parameter HR [95% CI] p-value
H7_VASCCILIARY 1.647 [1.36, 1.99] < 0.001
Birth year 0.986 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 628 out of 2837 males with H7_VASCCILIARY died.

Mortality risk

Mortality risk for people of age

years, who have H7_VASCCILIARY.

N-year risk Females Males
1 0.142% 0.259%
5 0.861% 1.779%
10 2.386% 4.403%
15 4.604% 8.327%
20 8.298% 13.714%

Relationships between endpoints

↥

Index endpoint: H7_VASCCILIARY – Hyphaema and other vascular disorders of iris and ciliary body

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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