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Androgenic alopecia

DOID EFO Endpoint Browser PheWeb

L12_ALOPECANDRO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L64
  • Hospital discharge: ICD-9 — 7040A
  • Cause of death: ICD-10 — L64
  • Cause of death: ICD-9 — 7040A

2 out of 7 registries used, show all original rules.

328

4. Check minimum number of events

None

328

5. Include endpoints

None

328

6. Filter based on genotype QC (FinnGen only)

313

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alopecia androgenica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1684 1684 -
Only index persons 1625 1625 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 43.96 -
Only index persons - 43.20 -

-FinnGen-

Key figures

All Female Male
Number of individuals 313 313 -
Unadjusted period prevalence (%) 0.11 0.11 -
Median age at first event (years) 51.69 51.69 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
328
Matched controls
3280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L64.9
ICD-10 Finland
Androgenic alopecia, unspecified
4940.9
233.6
197
*
L64.8
ICD-10 Finland
Other androgenic alopecia
+∞
139.9
124
*
C03DA01
ATC
spironolactone; oral
11.3
88.9
115
150
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
158.5
28.1
29
*
L63.9
ICD-10 Finland
Alopecia areata, unspecified
158.5
28.1
29
*
D07AC01
ATC
betamethasone; topical
3.4
25.9
176
841
L63.8
ICD-10 Finland
Other alopecia areata
269.7
25.0
25
*
D07AC13
ATC
mometasone; topical
2.9
19.8
144
691
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.6
18.0
68
220
L64.0
ICD-10 Finland
Drug-induced androgenic alopecia
+∞
14.7
14
*
G04CB01
ATC
finasteride; oral
+∞
14.7
14
*
L63.0
ICD-10 Finland
Alopecia (capitis) totalis
+∞
14.7
14
*
L65.8
ICD-10 Finland
Other specified nonscarring hair loss
78.5
13.7
15
*
L64
ICD-10 Finland
Androgenic alopecia
145.8
13.6
14
*
D07AD01
ATC
clobetasol; topical
2.8
13.3
85
370
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
12.7
44
133
S23
ICPC
Hair loss/baldness
19.0
12.2
18
10
N06AB05
ATC
paroxetine; oral
3.9
11.7
36
100
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
10.9
128
728
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
10.7
89
435
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
10.2
113
623
B07.9
ICD-10 Finland
Verruca simplex
4.9
10.2
23
50
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
10.1
175
1150
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
9.9
152
952
XQ802
NOMESCO Finland
Epicutan test
3.7
9.3
31
91
L60.0
ICD-10 Finland
Ingrowing nail
4.4
9.1
23
55
E0000UV, ,
ATC
2.0
9.1
164
1081
H03AA01
ATC
levothyroxine sodium; systemic
2.1
8.9
114
660
L72.1
ICD-10 Finland
Trichilemmal cyst
4.1
8.9
25
65
L68.0
ICD-10 Finland
Hirsutism
51.4
8.7
10
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
8.3
86
458
G03HB01
ATC
cyproterone and estrogen; oral
2.4
8.1
62
289
L82
ICD-10 Finland
Seborrhoeic keratosis
2.2
8.0
75
382
L21.0
ICD-10 Finland
Seborrhoea capitis
12.2
7.6
13
11
J01AA04
ATC
lymecycline; systemic
2.5
7.4
53
239
G03HA01
ATC
cyproterone; systemic
81.9
7.4
8
*
L70.0
ICD-10 Finland
Acne vulgaris
13.8
7.4
12
9
R13
ICD-10 Finland
Dysphagia
3.1
7.3
32
112
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
6.9
39
157
L71.8
ICD-10 Finland
Other rosacea
17.1
6.8
10
6
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
6.6
84
480
D10BA01
ATC
isotretinoin; oral
3.1
6.5
28
97
N06AX21
ATC
duloxetine; oral
2.2
6.4
58
290
L71.9
ICD-10 Finland
Rosacea, unspecified
7.3
6.3
14
20
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
6.2
82
472
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.1
129
864
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
6.1
104
652
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.5
6.1
41
180
SPAT1301
SPAT
No procedures
1.8
6.0
110
705
R60.9
ICD-10 Finland
Oedema, unspecified
3.3
6.0
23
74

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
45
114
4.42
16.64
1.3
1.3
0.28
0.26
u/ml
—
6
8
133
751
2.30
11.65
1.5
1.3
0.93
1.93
u/ml
0.81
38
205
203
1380
2.24
11.09
3.4
2.8
71.75
77.80
ug/l
0.33
196
1281
295
2402
3.27
10.31
6.5
4.3
14.86
14.55
pmol/l
1.35
277
2212
131
807
2.04
8.63
3.1
2.2
60.43
57.79
u/l
0.18
120
744
80
414
2.23
8.25
1.3
1.4
1048.00
523.83
titre
0.49
15
94
42
163
2.81
7.97
1.2
1.1
—
106.00
—
0
5
262
2111
2.20
7.64
7.0
6.7
73.77
75.18
u/l
0.30
244
1966
177
1249
1.91
7.55
2.2
2.0
—
—
—
0
0
156
1061
1.90
7.41
5.1
4.0
36.77
36.19
g/l
0.77
148
992
165
1145
1.89
7.34
4.6
3.1
6.38
5.85
ph
1.94
13
85
177
1257
1.89
7.32
2.4
2.3
81.24
78.30
nmol/l
0.75
169
1133
154
1046
1.89
7.32
2.2
1.9
97.46
99.34
pmol/l
0.21
84
497
45
190
2.59
7.25
4.7
3.2
—
—
—
0
0
262
2127
2.15
7.24
5.1
4.0
11.38
11.04
mm/h
0.18
250
1961
74
395
2.13
6.97
1.6
2.0
132.25
109.07
ug/g
0.18
58
307
134
883
1.88
6.90
2.8
2.7
—
—
—
0
0
179
1292
1.85
6.88
6.5
5.6
1.21
1.23
mmol/l
2.23
161
1090
104
637
1.93
6.65
2.4
2.0
2.95
2.95
mg/l
0.00
94
533
60
304
2.19
6.42
1.5
1.3
—
—
—
0
0
192
1438
1.81
6.33
5.3
5.6
0.19
0.17
e9/l
0.62
177
1269
186
1381
1.80
6.31
5.2
5.2
0.51
0.53
e9/l
0.92
169
1199
188
1404
1.79
6.22
6.6
4.7
0.00
0.00
estimate
0.50
32
281
133
897
1.81
6.20
3.4
3.1
12.10
23.99
ng/l
1.04
78
531
188
1406
1.79
6.17
5.0
3.5
0.00
0.00
estimate
-0.00
35
293
186
1389
1.78
6.11
5.2
5.2
0.04
0.04
e9/l
0.16
169
1205
95
579
1.90
6.10
1.3
1.3
34.39
36.38
iu/ml
0.03
26
192
33
130
2.71
6.09
2.4
2.4
—
—
—
0
0
189
1423
1.77
5.99
5.7
5.2
1.91
2.01
e9/l
0.45
176
1269
308
2743
3.01
5.87
7.9
5.1
1.75
2.23
mu/l
0.56
296
2545
188
1419
1.76
5.85
5.1
3.5
0.00
0.02
estimate
0.80
33
276
102
646
1.84
5.77
1.7
1.6
0.95
0.82
mg/l
0.23
75
486
185
1398
1.74
5.66
5.0
5.3
8.98
9.60
umol/l
0.80
177
1313
101
642
1.83
5.63
4.7
3.3
—
—
—
0
0
87
533
1.86
5.43
1.8
1.6
464.51
27640903.61
pmol/l
0.78
74
445
232
1887
1.78
5.31
5.6
4.3
—
2095.67
—
0
27
43
205
2.26
5.31
1.4
1.3
19.08
26.37
iu/l
0.99
36
180
79
473
1.88
5.28
2.5
2.6
2.42
2.45
mmol/l
1.30
68
419
50
255
2.13
5.23
1.1
1.1
—
—
—
0
0
50
255
2.13
5.23
1.4
1.2
137.68
170.79
iu/ml
0.24
25
108
232
1893
1.77
5.19
4.1
3.2
—
—
—
0
0
204
1609
1.71
5.13
7.0
8.3
4.02
3.90
e9/l
0.30
182
1413
43
208
2.23
5.13
1.3
1.3
—
—
—
0
0
49
250
2.13
5.12
2.1
2.8
22.25
36.02
u/ml
0.70
44
238
63
355
1.96
5.03
2.4
2.2
13.48
13.90
umol/l
0.20
57
330
239
1975
1.77
5.02
5.5
4.1
—
—
—
0
0
114
774
1.72
4.98
2.3
2.0
152.15
141.75
u/l
0.14
109
732
51
268
2.07
4.94
2.1
1.4
—
—
—
0
0
53
283
2.04
4.92
2.3
2.2
4.20
5.28
umol/l
0.95
43
239
65
375
1.91
4.84
1.3
1.1
—
—
—
0
0
91
590
1.75
4.63
1.5
1.4
21.21
21.91
nmol/l
0.21
82
499
131
938
1.66
4.62
2.7
3.2
2.35
2.36
mmol/l
0.81
116
833
144
1061
1.64
4.51
13.6
8.9
1.14
1.12
inr
0.10
40
342
21
77
2.85
4.44
2.0
4.0
—
—
—
0
0
312
2859
2.87
4.43
16.5
12.2
3.95
3.91
mmol/l
1.43
305
2769
95
634
1.70
4.33
1.5
1.4
2.12
2.25
g/l
0.24
59
376
26
109
2.50
4.27
1.2
1.2
—
—
—
0
0
311
2853
2.74
4.25
16.5
12.2
139.37
139.77
mmol/l
2.04
305
2770
153
1161
1.60
4.16
6.0
4.8
1.21
1.22
mmol/l
2.36
143
1054
36
180
2.12
3.97
1.1
1.3
—
—
—
0
0
186
1489
1.58
3.94
5.9
3.9
6.49
6.46
mmol/l
0.09
180
1358
18
65
2.87
3.92
1.7
1.6
29.51
23.05
u/l
0.37
18
53
45
246
1.96
3.91
10.0
5.3
105.56
104.16
mmol/l
1.28
45
246
285
2545
1.91
3.90
6.9
5.0
39.52
38.53
mmol/mol
1.19
268
2380
10
19
5.39
3.85
1.0
1.1
—
—
—
0
0
318
2976
3.25
3.68
15.0
10.7
—
—
—
0
0
11
27
4.18
3.42
1.8
1.4
—
—
—
0
0
13
43
3.11
3.29
1.2
1.3
—
—
—
0
0
34
181
1.98
3.19
2.5
3.0
—
—
—
0
0
104
759
1.54
3.17
5.9
3.7
0.00
0.00
estimate
0.50
32
281
88
619
1.58
3.15
5.4
3.5
1.01
1.02
kg/l
—
7
84
299
2753
1.97
3.13
5.4
4.1
5.86
5.75
mmol/l
0.75
284
2550
306
2842
2.14
3.10
14.7
11.2
18.84
19.85
mg/l
0.25
249
2156
163
1315
1.48
3.04
6.0
5.6
—
—
—
0
0
14
51
2.82
3.02
1.1
1.0
1.48
2.12
u/ml
—
7
21
25
122
2.14
2.96
13.6
7.0
0.85
0.68
%
1.98
25
122
26
129
2.10
2.95
4.6
4.5
—
—
—
0
0
25
123
2.12
2.90
13.5
7.0
1.49
1.30
%
0.74
25
123
220
1894
1.49
2.88
3.5
2.8
36.99
38.40
u/l
0.17
209
1780
155
1248
1.46
2.86
5.0
5.4
0.65
0.71
%
0.85
143
1149
161
1307
1.46
2.84
5.1
5.6
7.99
8.09
%
0.17
148
1217
164
1337
1.45
2.83
5.5
5.4
29.38
29.39
%
0.00
153
1252
82
582
1.55
2.80
1.3
1.3
3.19
10.06
u/ml
1.85
47
227
64
429
1.61
2.79
3.2
3.2
213.32
240.94
ng/l
0.05
41
295
32
176
1.91
2.75
1.6
1.2
—
—
—
0
0
160
1304
1.44
2.73
4.9
5.3
2.96
2.78
%
0.57
148
1211
97
722
1.49
2.64
4.0
3.6
3.29
7.32
mg/mmol
1.55
63
401
100
751
1.48
2.60
3.2
2.8
6.97
7.02
mmol/l
0.04
90
627
14
56
2.57
2.56
1.1
1.1
0.56
2.06
u/ml
—
6
30
13
50
2.67
2.56
1.8
3.1
7.41
7.43
ph
1.57
13
44
31
175
1.85
2.48
2.5
2.9
2.04
2.27
mmol/l
0.13
25
146
92
687
1.47
2.44
3.3
3.0
14.35
252.25
mg/l
0.94
59
397
48
313
1.63
2.34
1.3
1.2
—
—
—
0
0
24
128
1.94
2.28
4.2
2.9
—
—
—
0
0
96
734
1.44
2.24
4.1
3.2
—
—
—
0
0
109
858
1.40
2.15
2.4
2.0
—
—
—
0
0
161
1353
1.37
2.14
3.0
2.4
—
—
—
0
0
37
232
1.67
2.10
12.3
6.3
12.98
13.24
kpa
0.09
37
226
37
232
1.67
2.10
12.3
6.3
4.96
5.20
kpa
1.18
37
226
20
103
2.00
2.10
17.8
7.8
—
—
—
0
0
5
10
5.06
2.08
2.0
1.1
—
—
—
0
0
37
233
1.66
2.07
12.3
6.4
0.91
1.30
mmol/l
0.24
32
186
158
1330
1.36
2.05
5.4
5.3
57.09
56.55
%
0.26
147
1242
46
307
1.58
2.05
2.4
2.2
23.14
23.09
%
0.01
38
256
286
2663
1.58
2.04
4.3
3.6
1.37
1.22
mmol/l
3.16
269
2462
298
2803
1.69
2.03
4.9
4.1
4.83
4.89
mmol/l
0.54
284
2618
301
2840
1.73
2.01
5.6
4.6
2.84
2.89
mmol/l
0.46
285
2648
88
675
1.42
2.00
2.8
2.7
0.20
0.46
e6/l
1.73
75
496
5
11
4.60
1.95
1.2
1.3
107.20
153.09
nmol/l
—
5
11
6
16
3.80
1.94
1.7
1.2
2.02
1.85
mmol/l
—
6
16
14
65
2.21
1.91
2.1
3.4
3.61
3.87
mmol/l
1.53
14
65
7
22
3.23
1.89
3.9
1.2
—
—
—
0
0
66
488
1.44
1.82
3.2
2.5
485.66
511.99
mosm/kgh2o
0.43
58
414
88
686
1.39
1.81
2.7
2.7
—
—
—
0
0
8
29
2.80
1.80
1.1
1.0
—
—
—
0
0
12
54
2.27
1.76
5.3
3.9
—
—
—
0
0
8
30
2.71
1.73
1.0
1.0
—
—
—
0
0
54
388
1.47
1.73
1.6
1.6
—
—
—
0
0
38
254
1.56
1.70
2.8
3.8
—
—
—
0
0
10
40
2.55
1.68
1.7
1.5
—
—
—
0
0
114
936
1.33
1.67
3.4
3.4
70.44
74.04
e6/l
0.03
87
618
12
56
2.19
1.63
3.5
2.7
4.18
4.48
e9/l
0.22
12
56
5
14
3.61
1.62
1.2
1.4
—
—
—
0
0
294
2783
1.54
1.61
4.9
4.1
1.53
1.60
mmol/l
2.05
281
2595
7
26
2.73
1.59
1.0
1.2
—
—
—
0
0
7
26
2.73
1.59
1.3
1.2
—
—
—
0
0
12
57
2.15
1.57
3.8
3.0
57.42
58.35
%
0.11
12
57
22
131
1.73
1.54
1.6
1.8
—
—
—
0
0
5
16
3.16
1.44
5.0
2.8
154.20
107.88
nmol/l
—
5
16
144
1242
1.28
1.43
7.7
8.2
0.00
0.00
e9/l
1.39
116
1015
17
96
1.81
1.42
1.5
1.2
—
—
—
0
0
11
53
2.11
1.40
2.1
1.8
—
—
—
0
0
9
41
2.23
1.38
1.9
2.8
13.11
13.20
%
—
9
41
44
321
1.43
1.32
1.6
1.5
—
—
—
0
0
6
24
2.53
1.31
1.2
1.5
—
—
—
0
0
46
340
1.41
1.29
2.2
1.8
—
—
—
0
0
70
556
1.33
1.27
2.9
3.4
—
—
—
0
0
8
38
2.13
1.19
1.9
1.4
—
—
—
0
0
89
740
1.28
1.15
2.8
2.9
24.52
42.78
e6/l
0.72
74
554
15
89
1.72
1.09
1.3
1.3
306.56
329.98
ug/g
—
9
48
8
41
1.97
1.09
1.1
1.2
—
—
nmol/l
—
0
0
15
90
1.70
1.06
1.3
1.3
—
—
—
0
0
55
435
1.32
1.03
1.6
1.6
1298.73
1204.71
nmol/l
0.30
41
318
9
47
1.94
1.03
1.3
1.1
—
—
—
0
0
9
47
1.94
1.03
3.9
2.2
6.63
7.06
mmol/l
—
9
47
9
48
1.90
1.01
3.9
2.2
1.52
1.25
mmol/l
—
9
48
94
800
1.25
1.00
3.3
3.4
7.40
7.40
ph
0.26
18
159
21
141
1.52
0.97
1.3
2.3
—
—
—
0
0
33
245
1.39
0.93
1.3
1.4
—
—
—
0
0
21
144
1.49
0.90
16.7
6.9
—
—
—
0
0
23
161
1.46
0.89
2.7
2.2
5645.20
3914.90
u/l
—
10
69
8
43
1.88
0.88
2.3
2.0
—
—
—
0
0
92
792
1.22
0.87
4.8
3.2
—
—
—
0
0
6
30
2.02
0.87
1.5
3.6
—
—
—
0
0
6
32
1.89
0.82
1.2
1.0
—
—
—
0
0
18
123
1.49
0.79
1.7
2.7
0.02
0.10
e6/l
1.71
18
118
0
25
0.00
0.79
0.0
3.9
—
—
—
0
0
45
362
1.28
0.77
1.3
1.2
—
—
—
0
0
7
38
1.86
0.74
1.0
1.2
—
—
—
0
0
31
241
1.32
0.69
1.4
1.3
—
—
—
0
0
7
43
1.64
0.67
3.7
5.6
364.71
393.89
umol/l
—
7
38
73
631
1.20
0.67
1.8
2.4
294.82
6665.14
umol/l
3.23
67
561
5
29
1.74
0.64
1.6
1.4
—
—
—
0
0
17
122
1.41
0.61
1.5
1.3
111.37
265.44
miu/ml
—
8
64
9
64
1.42
0.52
3.4
1.2
4.28
3.73
mmol/l
—
9
57
19
144
1.34
0.52
1.4
2.9
84.75
73.94
e9/l
0.40
13
113
6
40
1.51
0.52
1.2
1.2
—
—
—
0
0
6
40
1.51
0.52
2.0
2.0
—
—
—
0
0
13
93
1.41
0.49
1.8
2.0
1.20
1.13
%
0.14
13
93
11
76
1.46
0.48
1.5
2.5
—
—
—
0
0
89
805
1.14
0.48
1.7
1.6
1.44
1.34
mmol/l
0.62
82
699
7
48
1.47
0.47
1.6
1.5
—
—
—
0
0
24
297
0.79
0.47
1.2
1.3
—
—
—
0
0
12
86
1.41
0.45
10.8
6.7
—
—
—
0
0
13
95
1.38
0.44
3.3
1.9
2.77
6.17
iu/l
—
6
32
59
521
1.16
0.44
1.9
1.7
—
—
—
0
0
6
92
0.65
0.43
1.7
3.6
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
4.0
—
—
—
0
0
5
34
1.48
0.40
3.2
2.8
—
—
—
0
0
5
35
1.44
0.39
1.0
1.1
—
—
—
0
0
15
116
1.31
0.37
1.5
1.6
—
—
—
0
0
9
70
1.29
0.37
3.6
1.3
580.78
366.71
mg/l
—
9
63
113
1057
1.11
0.35
2.7
2.7
—
—
—
0
0
6
45
1.34
0.34
1.3
1.5
—
—
—
0
0
42
371
1.15
0.33
2.0
2.6
2.50
4.01
e6/l
0.99
28
190
76
699
1.11
0.32
4.4
6.4
—
—
—
0
0
44
392
1.14
0.31
1.6
1.9
—
—
—
0
0
15
120
1.26
0.30
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
5.1
1.2
—
—
—
0
0
9
117
0.76
0.28
1.8
1.4
—
—
—
0
0
9
116
0.77
0.28
1.8
1.4
—
—
—
0
0
9
119
0.75
0.28
1.8
1.5
—
—
—
0
0
28
247
1.15
0.23
6.1
3.7
—
—
—
0
0
21
181
1.17
0.23
4.0
2.7
—
—
—
0
0
5
39
1.29
0.23
1.0
5.9
—
—
—
0
0
5
39
1.29
0.23
2.0
1.2
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
52
1.16
0.19
1.0
5.1
13.82
23.93
mg/l
—
6
41
6
52
1.16
0.19
1.0
5.1
15.52
36.45
mg/l
—
6
43
5
69
0.72
0.17
2.2
1.8
—
—
—
0
0
16
143
1.12
0.11
1.3
1.1
—
—
—
0
0
29
271
1.08
0.10
2.5
3.8
2.95
9.79
ug/l
1.96
18
216
5
44
1.14
0.10
1.6
1.2
—
—
—
0
0
5
61
0.82
0.08
2.2
2.3
—
—
—
0
0
7
64
1.10
0.08
2.4
1.5
52.86
196.56
ug/l
—
7
55
37
356
1.04
0.05
1.6
1.4
—
—
—
0
0
11
120
0.91
0.05
1.3
1.3
—
—
—
0
0
85
866
0.98
0.05
1.5
1.5
—
—
—
0
0
20
211
0.94
0.04
1.9
1.4
—
—
—
0
0
21
202
1.04
0.02
1.7
1.3
—
—
—
0
0
11
104
1.06
0.01
1.4
1.3
—
—
—
0
0
11
104
1.06
0.01
1.4
1.3
—
—
—
0
0
11
104
1.06
0.01
1.4
1.3
—
—
—
0
0
11
104
1.06
0.01
1.4
1.3
—
—
—
0
0
22
214
1.03
0.00
1.5
1.7
—
—
—
0
0
10
98
1.02
0.00
1.2
1.3
—
—
—
0
0
61
613
0.99
0.00
2.3
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
66
0.91
-0.00
1.2
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.84
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
7.10
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
71
0.99
-0.00
1.1
1.4
—
—
—
0
0
8
83
0.96
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
150.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
10.1
—
—
—
0
0
8
85
0.94
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.8
1.6
0.77
0.82
nmol/l
—
5
43
8
79
1.01
-0.00
2.8
1.6
2.32
4.70
ug/l
—
8
73
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
9
94
0.96
-0.00
1.6
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.1
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.2
—
66.25
—
0
8

Mortality – FinRegistry

↥

Association

Association between endpoint L12_ALOPECANDRO and mortality.

Females

Parameter HR [95% CI] p-value
L12_ALOPECANDRO 1.266 [1.01, 1.59] 0.043
Birth year 0.997 [0.99, 1.01] 0.532

During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 1383 females with L12_ALOPECANDRO died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ALOPECANDRO.

N-year risk Females Males
1 0.143% No data
5 0.796% No data
10 1.985% No data
15 3.694% No data
20 6.598% No data

Relationships between endpoints

↥

Index endpoint: L12_ALOPECANDRO – Androgenic alopecia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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