Cyst of spleen

D3_CYSTSPLEEN

splenic disease: A disease involving the spleen.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D73.4 Cause of death: ICD-10 — D73.4 2 out of 7 registries used, show all original rules.	67
4. Check minimum number of events None	67
5. Include endpoints None	67
6. Filter based on genotype QC (FinnGen only)	67

Control definitions (FinnGen only)

Control exclude: D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D73
Name in latin: Cysta lienis

NAME	D3_CYSTSPLEEN
CONTROL_EXCLUDE	D3_BLOODOTHER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D734
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D734
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Cyst of spleen based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	480	271	208
Only index persons	434	248	186
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	41.06	42.38	39.37
Only index persons	43.35	44.73	41.52

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	67	47	20
Unadjusted period prevalence (%)	0.01	0.02	0.01
Median age at first event (years)	47.65	48.22	46.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
59: Matched controls
590

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D73.4

ICD-10 Finland

Cyst of spleen

+∞

84.6

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

13.5

9.8

JMA10

NOMESCO Finland

Transabdominal total splenectomy

+∞

8.5

JN1DG

NOMESCO Finland

Very extensive MRI examination of upper part of abdomen with high intensity magnet

+∞

6.4

R10.1

ICD-10 Finland

Pain localized to upper abdomen

5.3

6.0

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

3.43

4.59

1.4

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

160

2.91

4.38

1.7

1.9

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

3.22

3.74

1.2

3.0

30.5

29.5

0.14

(3000991) Gas panel - Venous blood

3.74

3.04

5.6

11.6

—

(3026389) Candida sp identified in Specimen by Organism specific culture

7.19

2.93

1.7

1.2

—

(3019060) Gas panel - Arterial blood

4.16

2.79

4.8

24.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.10

2.71

2.8

3.8

—

(3032080) INR in Blood by Coagulation assay

168

2.28

2.66

10.1

11.4

1.2

1.3

inr

—

(3031040) Bacteria [#/volume] in Urine by Automated count

365

2.46

2.63

5.2

3.9

—

37.2

—

(3022145) Colonoscopy Study observation

2.74

2.49

1.3

1.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

3.55

2.41

2.0

1.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.59

2.26

1.3

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

401

2.33

2.18

5.0

4.1

—

(3026008) Bacteria identified in Urine by Culture

155

2.11

2.15

3.5

2.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

132

2.13

2.09

1.8

1.7

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

209

2.02

2.06

9.3

8.6

1.2

mmol/l

1.24

195

(40761535) Cells panel - Urine sediment

2.99

2.02

3.9

3.2

—

(3026493) Urate [Moles/volume] in Serum or Plasma

135

2.07

1.96

1.9

3.0

323.4

336.3

umol/l

0.23

124

(3023368) Bacteria identified in Blood by Culture

112

2.12

1.91

6.2

4.6

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

227

1.89

1.76

12.3

9.1

1.2

mmol/l

0.69

199

(3016879) Cocaine [Presence] in Urine

3.00

1.70

1.7

1.3

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.00

1.70

2.7

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

142

1.94

1.67

5.3

—

(42870588) Differential panel, method unspecified - Blood

168

1.89

1.65

6.4

6.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

268

1.85

1.65

5.6

4.4

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.19

1.62

9.2

36.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.19

1.62

6.3

13.8

94.7

91.4

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

217

1.80

1.51

9.2

5.4

36.6

36.4

g/l

0.08

206

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.89

1.47

5.7

2.5

1.4

2.2

—

(36304419) Bacteria [Presence] in Urine

148

1.84

1.46

2.8

2.3

—

(3000764) Benzodiazepines [Presence] in Urine

2.57

1.43

1.7

1.3

—

(3028300) Cannabinoids [Presence] in Urine

2.57

1.43

1.7

1.3

—

(3027008) Opiates [Presence] in Urine

2.57

1.43

1.7

1.3

—

(3027944) Amphetamines [Presence] in Urine

2.57

1.43

1.7

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

100

1.94

1.40

1.9

1.7

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

185

1.77

1.39

4.0

4.1

44.5

28.2

u/l

0.42

179

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.09

1.38

1.4

—

(3020891) Body temperature

3.09

1.38

7.8

4.8

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

2.03

1.38

4.2

5.2

3.9

6.4

umol/l

1.30

(3025941) Bacteria identified in Stool by Culture

2.53

1.34

1.1

1.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.64

1.33

10.2

2.9

23.8

23.9

mmol/l

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

2.64

1.33

1.7

1.6

—

(3037522) Nuclear Ab [Titer] in Serum

1.96

1.32

1.5

1186.7

846.0

titre

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

2.91

1.31

2.2

1.3

9.6

14.5

ug/l

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

2.76

1.24

2.8

1.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.92

1.20

1.6

1.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

2.07

1.20

1.6

—

(3010813) Leukocytes [#/volume] in Blood

637

+∞

1.20

30.1

17.8

6.8

6.7

e9/l

0.09

624

(3000963) Hemoglobin [Mass/volume] in Blood

637

+∞

1.20

30.3

17.8

133.1

136.2

g/l

1.25

630

(3026361) Erythrocytes [#/volume] in Blood

636

+∞

1.20

30.1

17.8

4.4

4.5

e12/l

1.35

624

(3024731) MCV [Entitic volume]

636

+∞

1.20

29.9

17.7

91.6

90.7

0.93

630

(3035941) MCH [Entitic mass]

636

+∞

1.20

29.9

17.7

30.5

30.2

0.59

630

(3007461) Platelets [#/volume] in Blood

634

+∞

1.18

30.1

17.8

259.9

256.6

e9/l

0.14

623

(3002385) Erythrocyte distribution width [Ratio]

497

1.98

1.16

22.6

14.7

14.2

13.5

0.77

491

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

2.48

1.16

1.7

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.87

1.12

1.4

1.3

0.27

(3022313) Gas panel - Capillary blood

2.49

1.11

2.6

8.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

145

0.49

1.09

4.6

3.6

3.0

10.8

mg/mmol

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.37

1.05

1.6

1.2

—

(3042936) Bacteria identified in Isolate by Culture

1.82

1.04

1.9

2.7

—

(3018095) Leukocytes [#/volume] in Urine

198

1.61

1.03

3.6

3.1

10.9

50.5

e6/l

1.18

137

(3021601) Nitrite [Presence] in Urine by Test strip

283

1.59

1.03

5.9

4.1

0.0

estimate

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.11

1.03

1.0

1.3

—

(3012544) pH of Venous blood

1.92

1.01

9.8

4.8

—

(1002224) Polysomnography panel

0.00

1.00

0.0

1.0

—

(3035350) Ketones [Presence] in Urine by Test strip

285

1.57

0.99

4.6

3.0

0.0

estimate

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.34

0.96

11.0

3.6

119.8

135.8

g/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

139

1.63

0.94

2.1

1.4

2.2

2.4

g/l

0.17

(3009261) Glucose [Presence] in Urine by Test strip

288

1.54

0.93

4.6

3.0

0.0

estimate

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

122

1.65

0.92

4.9

2.9

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.97

0.91

1.5

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.93

0.90

1.5

1.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

187

1.54

0.86

3.7

2.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

108

1.63

0.83

2.1

2.2

—

(40761536) Microorganisms panel - Urine sediment

1.76

0.82

4.3

2.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.68

0.79

2.5

1.5

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.27

0.78

1.6

1.1

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.17

0.76

6.0

3.5

65.8

54.5

—

(3021589) Normoblasts [#/volume] in Blood

248

1.47

0.76

14.7

8.1

0.0

e9/l

0.00

201

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.62

0.74

2.6

2.2

1.7

0.6

e6/l

—

(3009542) Hematocrit [Volume Fraction] of Blood

541

1.76

0.73

17.2

13.2

40.7

40.8

0.03

430

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

221

1.46

0.73

5.5

3.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.79

0.72

1.7

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

2.00

0.72

1.4

1.6

—

(3012516) Albumin [Mass/volume] in Urine

136

0.61

0.70

3.4

2.8

3268.6

79.2

mg/l

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.72

0.65

5.0

5.8

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.72

0.62

2.2

8.1

23.4

24.3

mmol/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.61

0.0

1.5

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.61

0.0

5.3

—

96.5

—

(3015736) pH of Urine

218

1.40

0.60

4.7

2.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

135

1.46

0.59

1.3

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

101

1.49

0.55

1.4

2.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

194

1.37

0.52

2.2

1.8

101.7

95.3

pmol/l

0.48

104

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.58

0.50

1.1

1.5

—

(3044889) 12 lead EKG panel

363

1.33

0.48

3.7

3.3

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

150

1.37

0.47

1.6

1.4

0.5

1.1

u/ml

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.52

0.45

2.9

1.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

522

1.44

0.45

14.8

10.6

88.9

87.1

ml/min/173m2

0.24

410

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.66

0.44

3.4

1.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.44

0.43

3.0

219.9

116.5

ng/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.43

0.43

3.0

1.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.40

0.43

1.9

1.8

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.42

0.0

1.4

—

5.2

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.42

0.0

3.9

—

0.0

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.42

0.0

1.2

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.42

0.0

3.9

—

0.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

3.8

—

0.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

3.8

—

37.9

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.41

0.0

1.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

3.8

—

1.0

—

(3029937) Albumin [Presence] in Urine by Test strip

153

1.34

0.41

6.2

3.3

0.0

estimate

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.42

0.40

1.6

2.0

—

(3002256) Pathology report gross observation

1.35

0.39

1.3

1.2

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.40

0.35

7.7

4.2

62.2

76.7

ng/l

—

(3003694) ABO and Rh group [Type] in Blood

176

1.28

0.34

2.1

1.5

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

149

1.28

0.32

2.1

2.0

127.4

155.5

u/l

0.25

141

(3000492) Spirometry study

1.30

0.31

1.4

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

169

1.26

0.30

3.8

2.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.33

0.28

3.5

4.0

20.6

20.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

439

1.24

0.28

3.9

3.4

—

(3000494) Fungus identified in Specimen by Culture

0.65

0.27

1.0

1.7

—

(21494755) Public health laboratory ask at order entry panel

1.29

0.27

1.4

1.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

125

1.26

0.25

5.5

2.8

775.5

1046.3

ng/l

0.31

102

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.38

0.24

5.8

3.9

4.8

4.6

pmol/l

—

(4010399)

1.34

0.24

1.2

1.4

—

(4035726)

1.21

0.22

1.6

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

133

0.79

0.22

1.2

1.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(4268621)

0.00

0.21

0.0

1.9

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

8.0

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

1.8

—

86.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3017732) Neutrophils [#/volume] in Blood

1.30

0.21

1.5

2.5

3.4

4.1

e9/l

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.1

—

(4306422)

0.00

0.20

0.0

1.4

—

(3013512) EKG study

130

1.20

0.17

3.5

3.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.18

0.16

1.6

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

112

1.20

0.16

1.4

1.3

167.5

20.5

iu/ml

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

180

1.16

0.15

5.3

3.1

80.3

22.2

ng/l

0.60

106

(3009508) Creatinine [Moles/volume] in Urine

159

0.85

0.15

2.8

2.7

6.7

8.2

mmol/l

0.69

136

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.22

0.15

1.6

2.4

1.1

1.8

e6/l

—

(3044640) Blood type and Crossmatch panel - Blood

178

0.87

0.13

2.8

2.1

—

(40768804) Tissue Pathology biopsy report

242

1.12

0.12

2.6

2.0

—

(3022621) pH of Urine by Test strip

1.12

0.10

3.0

1.9

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.14

0.09

33.3

22.4

—

1.3

—

(36660697) Celiac disease serology panel - Serum

1.12

0.09

1.3

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

129

1.11

0.06

2.3

2.1

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

113

1.08

0.02

3.9

2.0

1.8

ug/l

0.16

102

(1761868) Lipid panel - Serum or Plasma

219

1.01

0.00

1.8

2.6

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

5.6

—

2.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.98

0.00

1.4

2.1

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

2.9

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(4281824)

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

1.9

—

50.9

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.1

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

5.8

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.4

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.5

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.6

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.7

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

10.8

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.8

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(4027681)

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

6.7

—

(4146454)

0.00

0.0

2.5

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3006571) Polymorphonuclear cells/100 leukocytes in Synovial fluid

0.00

0.0

1.4

—

61.6

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.0

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.1

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

10.2

—

0.7

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.7

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.7

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

4.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.4

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

3.0

—

13.3

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(40758558) Short blood count panel - Blood

150

1.00

0.00

5.1

6.3

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint D3_CYSTSPLEEN and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_CYSTSPLEEN.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: D3_CYSTSPLEEN – Cyst of spleen

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Cyst of spleen

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints