splenic disease: A disease involving the spleen.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
648 |
4. Check minimum number of eventsNone |
648 |
5. Include endpoints |
667 |
6. Filter based on genotype QC (FinnGen only) |
639 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D70-D77
- Name in latin
- Morbi lienis
Similar endpoints
↥List of similar endpoints to
Diseases of spleen
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4031 | 1960 | 2041 |
| Only index persons | 3439 | 1713 | 1726 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.06 | 0.06 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 59.75 | 60.79 | 58.66 |
| Only index persons | 58.74 | 59.31 | 58.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 639 | 324 | 315 |
| Unadjusted period prevalence (%) | 0.13 | 0.11 | 0.14 |
| Median age at first event (years) | 61.53 | 58.41 | 64.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 667
- Matched controls
- 6670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D73.5
ICD-10 Finland
Infarction of spleen
+∞
249.0
223
*
D73.1
ICD-10 Finland
Hypersplenism
+∞
170.3
156
*
XW000
NOMESCO Finland
Bone marrow biopsy
17.8
152.8
133
92
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.0
118.5
236
484
D73.9
ICD-10 Finland
Disease of spleen, unspecified
+∞
91.8
86
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
10.5
87.8
104
115
JMA10
NOMESCO Finland
Transabdominal total splenectomy
100.9
73.8
80
9
D73.4
ICD-10 Finland
Cyst of spleen
+∞
73.3
69
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.9
72.8
154
323
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.8
62.7
313
1257
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
60.9
159
397
WW500
NOMESCO Finland
Blood transfusion
8.7
60.4
81
104
D73.8
ICD-10 Finland
Other diseases of spleen
+∞
60.3
57
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
58.2
55
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.0
56.8
145
354
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
12.8
50.2
50
42
D64.9
ICD-10 Finland
Anaemia, unspecified
4.6
50.2
138
356
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
47.3
149
425
L01XX05
ATC
hydroxycarbamide; oral
17.5
45.6
38
23
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
126.2
44.4
47
*
R50.9
ICD-10 Finland
Fever, unspecified
3.7
44.2
171
562
WW200
NOMESCO Finland
Immunization
9.6
43.0
52
58
C03CA01
ATC
furosemide; systemic
3.0
40.8
283
1315
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
40.7
402
2259
M04AA01
ATC
allopurinol; systemic
3.7
40.1
152
490
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
39.2
325
1655
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
141.6
38.2
40
*
J01MA12
ATC
levofloxacin; systemic
3.2
37.9
192
741
JN4AD
NOMESCO Finland
Body CT examination
4.0
37.3
124
364
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
13.6
36.8
35
27
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
36.7
213
888
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
35.8
172
641
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.1
35.2
49
65
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.9
34.9
84
192
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.1
33.7
179
705
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.9
32.9
42
50
ZX120
NOMESCO Finland
Intravenous
3.8
31.2
106
314
JN4BD
NOMESCO Finland
Extensive body CT
3.6
30.9
117
373
D70.89
ICD-10 Finland
Neutropenic splenomegaly
111.9
29.9
32
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.3
29.4
51
86
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
9.7
29.4
35
38
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
28.7
227
1093
N28.0
ICD-10 Finland
Ischaemia and infarction of kidney
81.3
28.0
31
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
27.6
119
411
D73.3
ICD-10 Finland
Abscess of spleen
+∞
27.3
26
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.6
26.0
66
157
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
23.0
25.9
37
17
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
24.8
170
755
B01AB05
ATC
enoxaparin; parenteral
2.4
24.2
257
1398
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
8.4
24.1
32
40
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
20.5
23.7
35
18
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
56.1
23.2
27
5
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
124.3
22.7
24
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
7.9
22.2
31
41
B01AB10
ATC
tinzaparin; parenteral
3.2
22.1
99
348
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
21.9
157
709
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.5
21.7
36
58
N02AA05
ATC
oxycodone; systemic
2.5
21.6
161
740
UJF32
NOMESCO Finland
Coloscopy
2.3
21.2
219
1165
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
20.8
77
240
C03DA01
ATC
spironolactone; oral
2.8
20.7
117
467
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
20.6
99
362
WX892
NOMESCO Finland
Monitored bed care
3.4
20.5
80
258
H02AB06
ATC
prednisolone; systemic
2.1
20.2
356
2331
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
20.1
108
419
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.1
19.9
43
89
A02BC02
ATC
pantoprazole; systemic
2.3
19.4
482
3578
JN6AD
NOMESCO Finland
CT of torso and neck
8.2
19.3
26
33
JAH00
NOMESCO Finland
Laparotomy
5.1
19.0
41
85
A10AE04
ATC
insulin glargine; parenteral
2.9
18.7
96
363
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
18.3
199
1072
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.3
18.1
73
240
D45
ICD-10 Finland
Polycythaemia vera
17.1
18.0
28
17
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.6
17.8
43
98
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
17.7
124
550
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.0
17.3
31
54
A05AA02
ATC
ursodeoxycholic acid; oral
6.6
17.2
28
44
B01AA03
ATC
warfarin; systemic
2.3
17.2
154
762
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
16.9
248
1491
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
65.1
16.8
19
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.8
16.8
53
148
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
16.6
204
1145
C07AB07
ATC
bisoprolol; oral
2.0
16.6
352
2404
K86.3
ICD-10 Finland
Pseudocyst of pancreas
28.4
16.6
22
8
A41.9
ICD-10 Finland
Sepsis, unspecified
4.4
16.5
42
100
A10AB05
ATC
insulin aspart; parenteral
3.0
16.2
77
278
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
30.9
16.2
21
7
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.3
16.2
66
218
AA1AD
NOMESCO Finland
CT of head and brain
2.1
16.1
212
1220
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
16.0
131
622
B03XA02
ATC
darbepoetin alfa; parenteral
5.9
16.0
29
51
D73.2
ICD-10 Finland
Chronic congestive splenomegaly
+∞
15.7
15
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.3
15.7
62
201
TK800
NOMESCO Finland
Hemodialysis
5.6
15.6
30
56
WX402
NOMESCO Finland
General anaesthesia
2.2
15.5
157
814
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.5
15.1
25
40
127
Kela drug reimbursment
Transplant complication
6.7
15.0
24
37
N02AX02
ATC
tramadol; systemic, rectal
1.9
14.8
311
2093
Z3231
NOMESCO Finland
Registered nurse
2.0
14.7
205
1198
SPAT1255
SPAT
Intravenous administration of medicine
3.1
14.6
65
226
D75.2
ICD-10 Finland
Essential thrombocytosis
153.2
14.5
15
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
14.4
44
120
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.8
14.4
33
72
Z2221
NOMESCO Finland
Medical doctor
2.0
14.1
198
1158
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.9
13.8
42
114
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
5.9
13.8
25
44
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
13.7
358
2561
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
13.7
107
496
ZXD05
NOMESCO Finland
Urgent procedure
1.9
13.7
221
1355
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.3
13.6
36
88
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
13.6
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
13.5
84
349
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
13.2
13.5
23
18
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
6.2
13.5
23
38
N18.8
ICD-10 Finland
Other chronic renal failure
5.2
13.5
28
56
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
13.3
138
720
TGC00
NOMESCO Finland
Bronchial lavation
4.5
13.3
33
77
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
13.1
155
849
A46
ICD-10 Finland
Erysipelas
2.2
12.8
119
592
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
10.8
12.8
24
23
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.1
12.8
57
198
R4110
NOMESCO Finland
Physiotherapy
1.9
12.7
198
1195
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
71.3
12.6
14
*
9689/3-C42.2
ICD-O-3
Splenic marginal zone B-cell lymphoma of spleen
+∞
12.5
12
*
S36.0
ICD-10 Finland
Injury of spleen
24.9
12.5
17
7
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.2
12.5
50
163
J01DB01
ATC
cefalexin; oral
2.2
12.5
560
4707
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
132.4
12.5
13
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
12.3
48
154
R11
ICD-10 Finland
Nausea and vomiting
2.6
12.3
75
309
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
12.7
12.2
21
17
ZXE00
NOMESCO Finland
One hour or less
1.8
12.2
267
1791
A06AD11
ATC
lactulose; oral
2.2
12.1
113
564
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
21.8
12.1
17
8
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
12.0
53
183
PD5AD
NOMESCO Finland
CT of aorta
4.8
12.0
27
58
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.2
12.0
32
79
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
12.0
122
630
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.0
11.9
53
184
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
47.6
11.9
14
*
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
47.6
11.9
14
*
R06.0
ICD-10 Finland
Dyspnoea
1.9
11.9
194
1184
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
11.8
90
411
P01AB01
ATC
metronidazole; oral, rectal
1.8
11.8
271
1839
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
11.7
107
528
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
11.7
249
1649
Z51.5
ICD-10 Finland
Palliative care
2.7
11.7
66
261
J01MA02
ATC
ciprofloxacin; systemic
1.8
11.7
271
1842
L03AA02
ATC
filgrastim; parenteral
4.3
11.6
30
72
UJK02
NOMESCO Finland
ERCP
4.4
11.6
29
68
374
Kela drug reimbursment
Ruxolitinib
122.0
11.5
12
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.0
11.4
32
82
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.3
11.3
23
45
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.7
11.3
26
57
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
5.9
11.1
20
35
L03AA13
ATC
pegfilgrastim; parenteral
3.5
11.0
38
113
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
44.1
10.9
13
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
10.9
152
877
L04AA06
ATC
mycophenolic acid; systemic
5.3
10.9
22
43
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
18.2
10.8
16
9
WX872
NOMESCO Finland
Intensive care
3.1
10.7
46
157
JAH01
NOMESCO Finland
Laparoscopy
3.4
10.6
38
116
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
10.5
86
405
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
10.4
34
97
L01EJ01
ATC
ruxolitinib; oral
111.7
10.4
11
*
174
Kela drug reimbursment
Ruxolitinib
111.7
10.4
11
*
JLC10
NOMESCO Finland
Distal pancreatectomy
33.1
10.4
13
*
I50.0
ICD-10 Finland
Congestive heart failure
2.6
10.3
61
247
JKA20
NOMESCO Finland
Cholecystectomy
4.0
10.2
29
75
R04.0
ICD-10 Finland
Epistaxis
2.5
10.2
64
267
M10.9
ICD-10 Finland
Gout, unspecified
2.7
10.2
57
225
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.4
10.1
25
58
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
14.9
10.0
16
11
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
8.3
9.9
21
26
K86.1
ICD-10 Finland
Other chronic pancreatitis
10.8
9.8
18
17
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.0
9.7
21
27
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
5.1
9.6
20
40
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
15.3
9.5
15
10
R10.0
ICD-10 Finland
Acute abdomen
3.8
9.5
29
79
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.7
9.5
30
84
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
30.5
9.4
12
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
9.4
33
99
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.7
9.4
52
204
B99
ICPC
Blood/lymph/spleen disease other
22.1
9.4
13
6
K92.0
ICD-10 Finland
Haematemesis
3.9
9.3
27
71
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
9.3
130
748
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
9.3
156
952
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.2
239
1651
J01MA14
ATC
moxifloxacin; systemic
2.3
9.2
70
319
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
9.2
134
781
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.8
9.1
28
77
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
10.2
9.1
17
17
120
Kela drug reimbursment
Hypogammaglobulinaemia
37.2
9.0
11
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
9.0
37
123
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.7
8.9
50
197
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
7.0
8.9
21
31
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
8.9
146
884
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.8
8.9
20
43
S97
ICPC
Chronic ulcer skin
2.6
8.9
52
210
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.7
8.6
27
75
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
27.9
8.5
11
*
N03AX16
ATC
[U] pregabalin
1.8
8.5
156
976
UJF92
NOMESCO Finland
Capsular endoscopy
4.4
8.5
21
49
L04AD01
ATC
ciclosporin; systemic
4.6
8.4
20
45
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
8.4
33
107
L01XX35
ATC
anagrelide; oral
+∞
8.3
8
*
K65.0
ICD-10 Finland
Acute peritonitis
8.7
8.3
17
20
K29.7
ICD-10 Finland
Gastritis, unspecified
3.2
8.3
32
102
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
10.9
8.3
15
14
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.9
8.3
24
63
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.7
8.3
44
169
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.2
128
760
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
8.2
73
355
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.9
8.2
39
141
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.6
8.2
46
182
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
33.8
8.1
10
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.0
8.1
35
120
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.3
8.0
61
278
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
7.9
49
203
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.9
7.9
38
138
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
7.9
91
488
K92.1
ICD-10 Finland
Melaena
2.7
7.9
43
167
A04AA02
ATC
granisetron; systemic, transdermal
2.6
7.9
47
191
D64.8
ICD-10 Finland
Other specified anaemias
4.7
7.9
18
39
I81
ICD-10 Finland
Portal vein thrombosis
13.2
7.9
13
10
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.9
241
1722
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.9
124
739
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
8.6
7.8
16
19
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
8.6
7.8
16
19
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
9.6
7.8
15
16
H02AB04
ATC
methylprednisolone; systemic
1.9
7.8
101
565
KH1AD
NOMESCO Finland
CT of urinary organs
3.2
7.8
30
96
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.5
7.7
26
76
K83.0
ICD-10 Finland
Cholangitis
6.0
7.7
20
34
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
7.7
187
1260
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
7.7
37
135
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
7.6
38
141
L04AD02
ATC
tacrolimus; systemic
8.2
7.6
16
20
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
18.6
7.6
11
6
ZX108
NOMESCO Finland
Inhalation
12.0
7.6
13
11
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.5
7.6
26
77
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
10.2
7.6
14
14
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
10.2
7.6
14
14
B01AF02
ATC
apixaban; oral
2.0
7.5
85
453
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.3
7.5
19
45
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
7.4
94
521
WZC30
NOMESCO Finland
Teaching
1.9
7.4
110
642
A07AA09
ATC
vancomycin; oral
6.1
7.4
19
32
WX002
NOMESCO Finland
Sedation and analgesia
1.8
7.4
129
792
E87.5
ICD-10 Finland
Hyperkalaemia
4.2
7.3
19
46
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
9.5
7.3
14
15
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
7.3
7
*
A02BC05
ATC
esomeprazole; systemic
1.6
7.3
259
1911
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.8
7.2
22
60
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.4
7.2
51
225
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
30.4
7.2
9
*
N05CF01
ATC
zopiclone; oral
1.6
7.1
206
1445
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
20.3
7.1
10
5
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
20.3
7.1
10
5
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
7.1
177
1196
Z3226
NOMESCO Finland
Physiotherapist
1.8
7.1
120
729
R60.0
ICD-10 Finland
Localized oedema
2.0
7.1
82
441
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
7.1
63
307
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.6
7.1
42
171
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
7.0
30
102
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.1
7.0
16
23
GD1AD
NOMESCO Finland
Thorax CT examination
2.5
7.0
45
190
E0000UV, ,
ATC
1.6
7.0
258
1916
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.0
7.0
31
108
I50.1
ICD-10 Finland
Left ventricular failure
2.6
7.0
40
160
K76.9
ICD-10 Finland
Liver disease, unspecified
6.4
7.0
17
27
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
7.6
6.9
15
20
XF600
NOMESCO Finland
Bloodpressure measurement
2.4
6.9
45
192
3AC01, ,
NOMESCO Finland
8.4
6.9
14
17
R18
ICD-10 Finland
Ascites
3.9
6.8
20
53
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.8
116
706
V03AE01
ATC
polystyrene sulfonate; oral
6.2
6.8
17
28
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
6.8
143
924
R53
ICD-10 Finland
Malaise and fatigue
1.7
6.8
158
1049
K76.6
ICD-10 Finland
Portal hypertension
40.5
6.8
8
*
B03BA03
ATC
hydroxocobalamin; parenteral
2.5
6.8
43
181
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.3
6.8
25
78
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
6.8
145
942
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.4
6.7
24
73
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.7
453
3830
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.8
6.7
20
54
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
6.6
95
549
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.6
83
459
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
12.4
6.6
11
9
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
12.4
6.6
11
9
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
12.4
6.6
11
9
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
12.4
6.6
11
9
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.5
6.6
42
177
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.8
6.6
13
15
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
6.6
159
1065
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.9
6.6
31
112
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.5
6.6
39
159
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
6.5
26
85
R4190
NOMESCO Finland
Nutritional therapy
2.9
6.5
30
107
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.6
6.5
36
142
205
Kela drug reimbursment
Chronic hypertension
1.6
6.4
168
1147
WX882
NOMESCO Finland
High dependency care
3.2
6.4
25
81
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
6.4
91
525
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
6.4
159
1073
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.3
6.4
18
35
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
5.6
6.3
17
31
H02AB07
ATC
prednisone; oral
1.9
6.3
88
504
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.9
6.3
28
98
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
18.2
6.3
9
5
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
18.2
6.3
9
5
E87.6
ICD-10 Finland
Hypokalaemia
2.8
6.3
31
115
2895A
ICD-9 Finland
Other diseases of blood and blood-forming organs, Other diseases of spleen
+∞
6.3
6
*
JMW97
NOMESCO Finland
Other laparoscopic operation on spleen
+∞
6.3
6
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
+∞
6.3
6
*
JM1AT
NOMESCO Finland
Cytology of spleen with ultrasound guidance
+∞
6.3
6
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.0
6.3
70
372
K75.0
ICD-10 Finland
Abscess of liver
26.9
6.2
8
*
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
26.9
6.2
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.2
197
1406
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
6.2
65
337
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
6.2
35
139
ZX112
NOMESCO Finland
Subcutaneous
3.6
6.2
20
57
A12AA04
ATC
calcium carbonate; oral
4.0
6.2
17
43
N02BE01
ATC
paracetamol; systemic, rectal
1.8
6.2
577
5215
A41.8
ICD-10 Finland
Other specified sepsis
3.7
6.1
19
53
N19
ICD-10 Finland
Unspecified kidney failure
2.7
6.1
31
117
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.8
6.1
14
21
B28
ICPC
Limited function/disability (B)
10.1
6.0
11
11
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.0
379
3122
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
294
566
8.50
161.99
7.4
4.0
292.51
239.97
u/l
3.18
287
537
244
590
5.94
101.37
5.6
2.5
2.23
1.77
%
5.56
228
533
203
436
6.26
95.35
5.8
2.7
84.38
69.85
e9/l
3.87
162
334
185
405
5.94
84.32
3.6
2.4
10.54
10.79
g/l
0.26
167
375
83
78
12.01
78.22
2.4
3.1
713.88
3506.00
u/ml
—
8
7
90
105
9.75
72.66
6.8
5.7
218.31
272.57
iu/ml
0.18
16
14
486
2495
4.49
69.65
13.5
5.7
2.59
2.87
%
1.52
470
2347
256
845
4.29
69.16
3.4
2.1
31.71
29.78
s
2.54
249
822
234
723
4.45
69.11
4.2
2.5
22.62
22.85
%
0.07
203
620
99
140
8.13
68.32
2.9
2.8
198.03
183.24
%
0.72
94
135
149
324
5.63
67.43
2.2
1.6
1.16
1.52
g/l
0.89
133
303
490
2572
4.41
66.99
13.9
5.8
26.39
27.44
%
1.03
474
2426
519
2841
4.73
66.82
14.6
6.3
13.70
11.42
umol/l
2.78
504
2696
237
768
4.24
65.15
4.0
2.4
2.24
2.32
g/l
1.18
226
715
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
104
168
7.15
63.58
4.0
2.5
0.29
0.31
u/ml
0.21
77
86
245
836
4.05
62.28
4.1
2.4
11.86
13.03
umol/l
1.47
234
779
184
512
4.58
61.61
3.5
2.3
0.20
0.21
g/l
1.42
172
481
475
2541
4.02
60.68
12.8
5.6
57.88
57.64
%
0.15
458
2399
172
465
4.64
59.60
11.5
8.1
11.35
9.51
mmol/l
2.14
167
440
445
2320
3.76
58.19
11.4
4.8
33.75
35.63
g/l
8.12
432
2165
161
422
4.71
57.89
2.1
2.8
64.52
66.36
g/l
1.70
153
388
120
247
5.70
57.22
2.5
1.8
1.27
1.55
g/l
1.84
97
219
87
133
7.37
55.75
1.8
1.5
—
—
—
0
0
240
864
3.78
55.53
5.1
3.4
0.81
0.82
mmol/l
0.45
228
818
217
731
3.92
55.35
8.9
5.8
1.08
1.02
mmol/l
1.89
203
673
310
1336
3.47
53.89
3.1
2.1
3.88
3.01
mg/l
4.30
272
1147
522
3116
4.11
53.43
18.5
8.5
4.56
4.15
e9/l
1.54
484
2746
460
2547
3.60
52.58
23.7
14.9
1.31
1.28
inr
0.23
143
749
462
2623
3.48
49.44
13.6
7.0
1.20
1.21
mmol/l
1.76
399
2252
354
1722
3.25
49.19
5.2
2.5
58.70
104.45
u/l
0.50
335
1615
92
170
6.12
48.91
2.3
3.7
54.10
89.78
mg/l
0.44
76
136
92
170
6.12
48.91
2.3
3.7
44.64
31.86
mg/l
0.61
77
137
183
595
3.86
48.47
7.1
3.2
9.16
8.40
umol/l
0.22
167
524
55
57
10.43
48.06
1.1
1.0
—
—
—
0
0
90
166
6.11
47.91
2.3
3.6
1.27
1.98
ratio
—
7
18
298
1333
3.23
47.39
10.5
4.0
81.80
90.39
%
6.53
290
1301
430
2388
3.25
46.73
11.8
6.1
1.20
1.21
mmol/l
3.23
407
2176
300
1401
3.07
43.44
4.5
2.7
1662.55
7422.55
umol/l
2.45
269
1225
75
127
6.53
43.39
4.9
2.8
40.51
33.77
umol/l
1.31
69
114
57
76
8.11
40.91
1.2
1.1
84.30
33.55
u/l
0.62
45
68
342
1777
2.90
39.86
6.6
3.4
39.85
32.62
u/l
1.56
333
1696
216
880
3.15
39.06
3.0
1.9
—
—
—
0
0
86
184
5.22
38.76
2.0
2.1
—
—
—
0
0
86
184
5.22
38.76
2.0
2.1
6.87
7.41
g/l
1.68
78
167
36
27
14.04
38.51
1.3
1.2
—
—
—
0
0
319
1631
2.83
37.82
4.3
3.2
44.62
91.51
e6/l
0.54
267
1265
85
184
5.15
37.77
2.0
2.1
3.30
3.63
g/l
1.70
78
167
60
93
6.99
37.67
1.6
1.5
109.29
108.10
u/ml
0.04
14
20
35
26
14.15
37.63
1.9
1.7
—
—
—
0
0
256
1172
2.92
37.30
2.6
1.7
1.66
1.20
mg/l
1.66
211
896
351
1898
2.79
37.14
5.0
3.6
141.51
101.06
e6/l
0.22
283
1368
425
2536
2.86
37.10
6.0
2.5
—
—
—
0
0
298
1484
2.82
36.96
4.3
3.1
0.36
0.47
e6/l
0.60
247
1128
61
101
6.55
35.95
1.4
1.2
—
—
—
0
0
398
2322
2.77
35.85
5.5
2.7
277.76
127.15
ug/l
2.50
383
2139
87
203
4.78
35.31
2.5
1.8
3.55
2.83
ug/l
0.15
79
180
79
171
5.11
35.04
2.1
2.2
10.20
10.36
g/l
0.10
71
153
578
4160
3.92
34.92
19.5
7.5
91.15
77.79
u/l
8.19
565
3914
125
387
3.74
34.72
2.4
1.7
—
—
—
0
0
245
1131
2.84
34.71
3.3
2.5
6.98
5.19
e6/l
0.99
232
1021
59
98
6.51
34.65
1.4
1.2
311.27
278.41
u/ml
0.29
37
62
68
131
5.67
34.32
2.3
1.6
—
—
—
0
0
161
591
3.27
34.24
2.7
1.8
—
—
—
0
0
223
992
2.87
33.73
2.0
1.7
1134.54
1197.58
nmol/l
0.45
179
761
76
171
4.89
32.15
2.1
2.2
3.12
3.04
g/l
0.19
68
154
65
128
5.52
32.00
2.4
1.6
—
—
—
0
0
223
1035
2.73
30.64
2.1
1.4
2.42
2.45
g/l
0.05
160
659
156
599
3.09
30.44
2.8
1.9
—
—
—
0
0
70
156
4.90
29.91
2.3
2.4
0.49
0.88
g/l
0.46
62
138
135
482
3.26
29.75
4.9
2.4
37.07
42.16
u/l
0.21
118
405
138
505
3.18
29.14
7.1
3.5
1.83
2.04
mmol/l
0.29
116
416
85
226
4.16
29.05
2.1
2.0
43.29
38.09
u/l
0.80
75
207
65
144
4.89
27.94
1.7
2.3
0.01
0.04
g/l
0.32
59
131
474
3236
2.61
27.73
10.2
4.8
7.06
6.72
mmol/l
2.27
461
3015
288
1572
2.46
27.68
4.5
3.0
1941.50
1367.47
ng/l
1.03
273
1346
251
1290
2.52
27.45
5.8
2.3
—
—
—
0
0
50
93
5.73
26.10
2.4
1.6
—
—
—
0
0
64
148
4.68
26.10
1.9
2.2
37.36
37.53
g/l
0.06
56
131
66
157
4.56
25.99
2.2
1.6
—
—
—
0
0
50
94
5.67
25.80
1.7
1.5
—
—
—
0
0
150
616
2.85
25.56
10.1
8.7
11.70
12.18
kpa
0.47
144
595
150
616
2.85
25.56
10.2
8.7
5.04
5.09
kpa
0.28
145
593
60
135
4.78
25.28
1.7
2.4
0.00
0.00
g/l
-0.00
54
122
138
545
2.93
25.25
3.1
4.5
24.47
32.01
ug/l
0.12
113
456
50
96
5.55
25.22
2.4
1.6
—
—
—
0
0
50
96
5.55
25.22
2.4
1.6
—
—
—
0
0
64
153
4.52
25.03
1.6
1.2
—
—
—
0
0
149
616
2.83
25.03
10.3
8.7
1.15
1.08
mmol/l
0.07
121
497
540
4030
2.79
24.58
6.9
4.0
16.73
11.98
mm/h
6.64
519
3707
352
2185
2.29
24.24
2.5
2.0
92.33
94.98
pmol/l
0.49
219
1148
27
28
10.01
23.36
1.4
1.5
—
—
—
0
0
27
28
10.01
23.36
1.4
1.5
—
—
—
0
0
42
74
5.99
23.16
1.7
1.4
—
—
—
0
0
44
83
5.60
22.60
1.5
1.3
9.92
4.65
u/ml
0.29
25
31
492
3592
2.41
22.07
6.4
4.3
35.17
2823.71
e6/l
—
6
62
41
74
5.84
22.05
1.5
1.5
—
—
—
0
0
44
85
5.47
22.02
1.5
1.3
6.48
4.69
u/ml
0.23
27
36
94
334
3.11
20.51
1.7
1.4
—
—
—
0
0
337
2154
2.14
20.42
2.9
2.2
74.80
76.04
nmol/l
0.32
309
1922
83
276
3.29
20.21
5.3
2.4
1.50
1.19
%
1.11
83
276
118
492
2.70
19.15
2.4
1.9
367.28
371.80
nmol/l
0.08
110
449
170
843
2.36
19.09
3.7
3.0
4.14
2.31
e6/l
1.18
91
456
273
1644
2.12
18.96
2.8
2.1
153.98
312.78
u/l
1.64
267
1548
40
83
5.06
18.48
1.8
1.5
—
—
—
0
0
177
905
2.30
18.45
3.6
2.7
1.43
1.08
e6/l
0.58
100
515
63
187
3.62
18.26
2.3
2.9
—
—
—
0
0
68
213
3.44
18.17
3.0
3.6
53.33
1265.94
u/ml
0.99
60
183
78
267
3.18
18.06
5.4
2.3
0.67
0.65
%
0.16
78
267
35
66
5.54
17.96
2.0
1.6
—
—
—
0
0
35
66
5.54
17.96
2.0
1.6
—
—
—
0
0
190
1013
2.22
17.82
5.2
3.8
444.84
396.26
ng/l
0.10
157
777
35
68
5.38
17.39
4.6
2.0
32.49
33.53
pg
0.72
35
68
287
1805
2.04
17.34
4.8
3.3
2.33
2.35
mmol/l
1.86
259
1595
34
65
5.46
17.19
2.5
1.7
—
—
—
0
0
80
286
3.04
17.19
14.4
12.4
—
—
—
0
0
93
362
2.82
17.14
5.1
3.7
5.07
5.11
kpa
0.19
88
348
32
58
5.74
17.11
1.8
1.5
—
—
—
0
0
32
58
5.74
17.11
2.6
1.8
—
—
—
0
0
35
70
5.22
16.84
1.8
1.5
—
—
—
0
0
26
39
6.90
16.69
1.8
2.5
43.35
42.29
%
0.09
15
23
100
410
2.69
16.67
5.6
3.8
109.60
81.23
ng/l
1.37
92
362
88
338
2.85
16.61
4.8
3.8
1.81
1.64
mmol/l
0.18
63
267
38
83
4.79
16.54
1.2
1.1
—
—
—
0
0
221
1293
2.06
16.04
2.1
1.5
19.55
20.70
nmol/l
0.52
202
1110
41
99
4.35
15.78
6.3
3.7
57.07
57.46
%
0.05
41
99
470
3598
2.04
15.42
6.5
3.2
74.44
48.83
u/l
5.62
443
3378
27
23
12.18
15.18
2.7
4.3
80.81
100.00
%
1.60
27
23
30
58
5.37
14.98
2.2
2.4
—
—
—
0
0
82
321
2.77
14.89
2.3
1.7
—
—
—
0
0
41
106
4.06
14.43
2.0
1.6
—
—
—
0
0
52
159
3.46
14.39
1.3
1.3
—
—
—
0
0
28
54
5.37
14.01
2.6
1.6
—
—
—
0
0
28
54
5.37
14.01
2.6
1.6
—
—
—
0
0
28
54
5.37
14.01
2.6
1.6
—
—
—
0
0
370
2665
1.87
13.93
5.1
3.6
0.00
0.00
estimate
0.50
96
543
103
467
2.43
13.83
2.8
2.4
9.23
6.69
ug/l
0.56
85
420
367
2664
1.84
13.20
6.8
4.9
0.00
0.00
estimate
0.50
89
506
31
70
4.60
12.96
1.1
1.1
1.51
1.48
g/l
0.23
26
63
52
172
3.19
12.70
2.0
2.2
—
—
—
0
0
47
148
3.34
12.43
1.4
1.4
281.84
284.77
ug/g
0.03
32
86
367
2695
1.80
12.41
5.2
3.6
0.00
0.01
estimate
0.50
87
492
302
2096
1.81
12.31
6.3
3.7
64.39
50.07
ng/l
0.19
248
1486
31
75
4.29
11.91
1.2
1.3
—
—
—
0
0
26
55
4.88
11.74
1.2
1.2
—
—
—
0
0
170
1003
1.93
11.49
3.6
3.0
2.46
2.44
mmol/l
0.84
150
884
38
113
3.51
10.98
3.3
2.2
121.68
130.61
g/l
0.70
25
86
21
39
5.53
10.93
1.5
1.2
—
—
—
0
0
41
129
3.32
10.86
1.6
1.5
—
—
—
0
0
38
114
3.47
10.84
1.3
1.2
—
—
—
0
0
109
565
2.11
10.50
5.4
3.2
—
—
—
0
0
20
37
5.54
10.45
1.7
1.4
—
—
—
0
0
23
50
4.73
10.07
1.3
1.8
—
—
—
0
0
121
667
1.99
9.83
2.0
1.8
1.59
1.48
%
0.90
103
590
612
5464
2.46
9.71
41.7
13.9
27.77
23.62
mg/l
2.72
574
4314
34
104
3.39
9.43
1.4
1.3
—
—
—
0
0
34
104
3.39
9.43
1.4
1.3
—
—
—
0
0
86
424
2.18
9.38
7.1
3.7
1.22
1.23
mmol/l
0.77
80
373
17
16
10.87
9.33
3.0
1.6
30263.10
4193.22
e6/l
—
10
9
25
62
4.15
9.32
1.4
1.4
—
—
—
0
0
20
27
7.60
8.98
1.5
1.1
1.29
1.05
ratio
—
7
9
33
103
3.32
8.87
3.9
2.9
0.78
0.93
nmol/l
0.85
22
82
33
104
3.29
8.74
4.3
2.3
14.93
16.25
%
0.77
20
52
29
84
3.56
8.73
1.3
1.1
—
—
—
0
0
15
13
11.77
8.60
1.0
1.0
—
—
—
0
0
21
33
6.53
8.54
1.4
1.2
—
—
—
0
0
21
33
6.53
8.54
3.3
1.4
—
—
—
0
0
21
49
4.39
8.45
1.1
1.0
—
—
—
0
0
16
17
9.61
8.31
4.0
1.2
—
—
—
0
0
42
158
2.77
8.22
1.6
1.6
0.00
0.11
iu/ml
—
8
31
615
5574
2.33
8.17
43.7
16.4
138.93
139.68
mmol/l
9.96
607
5429
616
5591
2.33
8.08
44.6
16.5
3.98
3.98
mmol/l
0.12
608
5438
483
4081
1.67
7.82
4.7
3.9
14.81
14.80
pmol/l
0.03
454
3710
113
656
1.87
7.79
2.9
2.4
288.54
124.03
ug/g
1.02
91
530
32
107
3.09
7.72
2.1
3.8
753.25
423.93
u/ml
0.17
26
102
36
129
2.89
7.71
1.4
1.2
1.40
2.62
u/ml
—
5
17
11
6
18.61
7.62
1.4
1.3
—
—
—
0
0
36
130
2.87
7.60
1.4
1.2
8.13
1.94
u/ml
—
8
24
142
904
1.73
7.15
1.4
1.3
95.92
34.97
iu/ml
0.94
45
293
11
8
13.95
6.91
2.2
1.4
—
—
—
0
0
20
54
3.79
6.68
2.6
2.8
—
—
—
0
0
50
227
2.30
6.66
5.2
4.4
25.09
24.89
mmol/l
0.22
45
217
172
1173
1.63
6.62
1.4
1.2
1.42
1.67
u/ml
0.17
39
342
134
859
1.70
6.54
1.3
1.3
22.36
11.31
u/ml
0.52
42
353
205
1471
1.57
6.34
5.9
3.9
0.00
0.01
estimate
1.08
78
492
6
0
+∞
6.26
1.0
0.0
—
—
—
0
0
568
5111
1.75
6.18
32.9
12.9
78.97
80.98
ml/min/173m2
1.04
495
4219
275
2120
1.51
6.06
5.7
3.8
—
—
—
0
0
34
135
2.60
6.04
2.2
1.4
—
—
—
0
0
16
29
5.63
6.02
1.9
1.4
—
—
—
0
0
16
29
5.63
6.02
1.9
1.4
—
—
—
0
0
16
30
5.44
5.87
1.7
1.4
—
—
—
0
0
35
144
2.51
5.79
1.8
1.3
—
—
—
0
0
16
31
5.26
5.73
3.3
1.6
—
—
—
0
0
16
31
5.26
5.73
3.3
1.6
—
—
—
0
0
14
23
6.19
5.71
3.5
1.8
—
—
—
0
0
14
23
6.19
5.71
3.5
1.8
—
—
—
0
0
9
7
13.01
5.59
1.1
1.6
—
—
—
0
0
14
24
5.93
5.55
3.5
1.8
—
—
—
0
0
49
239
2.13
5.52
3.1
1.8
—
—
—
0
0
403
3393
1.47
5.51
3.6
2.9
—
—
—
0
0
75
427
1.85
5.46
3.8
2.6
50.15
64.81
ml/min/173m2
2.33
40
172
8
5
16.18
5.42
1.0
2.0
—
—
—
0
0
57
299
1.99
5.29
4.0
3.6
4.22
4.55
pmol/l
2.12
51
267
14
27
5.27
5.10
1.1
1.0
—
—
—
0
0
14
27
5.27
5.10
1.4
2.1
53.40
67.53
umol/l
—
5
15
13
23
5.74
5.08
1.8
1.4
—
—
—
0
0
13
23
5.74
5.08
1.8
1.4
—
—
—
0
0
16
45
3.62
5.07
1.0
1.5
—
—
—
0
0
45
220
2.12
5.05
2.4
1.7
—
—
—
0
0
11
16
6.97
4.97
1.0
1.9
—
—
—
0
0
38
176
2.23
4.88
2.3
1.5
—
—
—
0
0
41
201
2.11
4.59
5.6
3.4
1.48
1.39
mmol/l
0.28
41
196
544
4941
1.55
4.56
5.7
4.6
1.94
2.17
mu/l
0.43
515
4523
8
8
10.10
4.53
1.4
1.1
94.00
102.25
%
—
8
8
618
5804
1.88
4.46
24.7
10.2
31.15
26.53
u/l
1.27
606
5603
21
77
2.78
4.38
2.7
1.5
—
—
—
0
0
21
77
2.78
4.38
2.7
1.5
—
—
—
0
0
21
77
2.78
4.38
2.7
1.5
—
—
—
0
0
21
78
2.75
4.29
2.7
1.5
—
—
—
0
0
19
67
2.89
4.25
1.1
1.0
—
—
—
0
0
21
79
2.71
4.19
2.7
1.5
—
—
—
0
0
21
79
2.71
4.19
2.7
1.5
—
—
—
0
0
158
1162
1.47
4.13
1.8
1.7
461.48
431.17
pmol/l
0.78
141
963
18
63
2.91
4.09
1.6
1.4
1290.50
1699.23
e6/l
0.38
12
40
28
123
2.33
4.09
1.3
1.3
—
—
—
0
0
8
10
8.08
4.07
1.9
1.7
—
—
—
0
0
7
7
10.09
4.02
1.0
4.1
—
—
—
0
0
26
112
2.38
3.97
1.5
1.2
5.17
13.88
e6/l
0.60
18
86
12
27
4.51
3.95
2.2
1.4
—
—
—
0
0
12
27
4.51
3.95
2.2
1.4
—
—
—
0
0
15
49
3.11
3.82
1.1
1.2
—
—
—
0
0
13
33
4.00
3.81
7.8
3.7
—
—
—
0
0
204
1594
1.40
3.81
3.6
3.3
1427.19
182.92
mg/l
1.41
150
1057
18
66
2.78
3.78
2.4
3.6
—
—
—
0
0
35
176
2.04
3.70
1.2
1.1
—
—
—
0
0
216
1713
1.39
3.67
3.5
3.2
6.71
7.78
mmol/l
3.63
184
1449
35
177
2.03
3.65
1.2
1.1
—
—
—
0
0
10
21
4.82
3.56
1.1
1.0
—
—
—
0
0
33
166
2.04
3.50
1.2
1.3
126.95
225.16
miu/ml
—
8
84
6
6
10.07
3.50
10.8
4.3
5.65
7.33
mmol/l
—
6
6
212
1688
1.38
3.49
4.3
3.9
25.65
8.91
mg/mmol
1.82
158
1097
13
42
3.14
3.38
1.2
1.1
—
—
—
0
0
13
42
3.14
3.38
1.2
1.1
—
—
—
0
0
9
18
5.05
3.38
1.1
1.1
1737.44
1392.83
miu/ml
—
9
18
7
10
7.06
3.37
2.4
1.2
—
—
—
0
0
27
128
2.16
3.34
2.1
1.6
19139.74
14186.19
e6/l
0.29
19
97
13
43
3.06
3.26
1.2
1.1
—
—
—
0
0
13
43
3.06
3.26
1.2
1.1
—
—
—
0
0
13
43
3.06
3.26
1.2
1.1
—
—
—
0
0
20
86
2.37
3.10
4.3
2.9
103.50
105.36
mmol/l
0.69
20
86
20
86
2.37
3.10
4.3
2.9
4.19
4.07
mmol/l
0.86
20
86
15
56
2.72
3.07
1.0
1.1
—
—
—
0
0
6
8
7.56
3.06
2.5
3.4
27.47
76.64
pmol/l
—
6
8
7
12
5.88
3.02
1.0
1.3
—
—
—
0
0
18
75
2.44
2.99
1.4
1.3
0.59
0.57
nmol/l
0.09
18
70
10
26
3.89
2.99
1.1
1.2
91.80
94.31
u/l
—
10
26
15
57
2.67
2.98
1.0
1.1
—
—
—
0
0
13
46
2.86
2.93
1.0
1.1
—
—
—
0
0
8
17
4.75
2.92
1.0
1.1
—
—
—
0
0
22
102
2.20
2.90
2.0
1.7
—
—
—
0
0
9
22
4.13
2.89
3.3
1.9
22.44
28.36
umol/l
—
9
22
537
4989
1.39
2.88
7.2
5.8
40.66
39.91
mmol/mol
0.74
490
4668
156
1218
1.37
2.84
5.8
3.9
1.01
1.02
kg/l
1.66
26
166
9
23
3.95
2.78
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
34
3.27
2.73
1.2
1.2
—
—
—
0
0
561
5272
1.40
2.63
5.4
4.6
6.16
5.96
mmol/l
2.04
515
4819
5
7
7.19
2.55
1.4
1.9
—
—
—
0
0
6
11
5.49
2.55
2.0
1.3
—
—
—
0
0
16
69
2.35
2.50
3.1
2.7
17.80
5.24
umol/l
—
8
48
11
37
3.01
2.49
2.0
1.5
—
—
—
0
0
26
137
1.93
2.49
1.4
1.3
—
—
—
0
0
27
472
0.55
2.40
1.4
1.6
—
—
—
0
0
14
58
2.44
2.38
1.6
1.5
7083.75
48222.93
e6/l
—
8
30
5
8
6.29
2.37
1.4
1.1
—
—
—
0
0
10
33
3.06
2.36
3.2
1.8
0.79
0.97
g/l
—
10
33
7
18
3.92
2.25
2.3
4.5
—
—
—
0
0
547
5158
1.34
2.19
4.7
3.9
1.43
1.30
mmol/l
3.30
499
4754
9
30
3.03
2.15
1.0
1.2
—
—
—
0
0
10
36
2.80
2.14
1.2
1.1
—
—
—
0
0
9
31
2.93
2.08
1.0
1.1
—
—
—
0
0
44
287
1.57
2.06
1.5
1.3
—
—
—
0
0
9
32
2.84
2.00
1.0
1.0
—
—
—
0
0
7
21
3.36
1.97
1.0
1.1
—
—
—
0
0
25
142
1.79
1.95
1.1
1.1
—
—
—
0
0
11
45
2.47
1.94
1.9
1.3
46028.00
391857.16
e6/l
—
5
31
625
6054
1.51
1.86
59.0
20.7
38.07
40.31
%
13.87
588
5660
625
6055
1.51
1.85
58.8
20.5
250.61
246.89
e9/l
0.31
618
5929
6
17
3.55
1.84
1.3
1.2
12.32
8.98
ug/l
—
6
17
25
145
1.75
1.84
1.6
1.6
1.98
6.48
iu/l
—
8
45
625
6059
1.50
1.79
58.7
20.5
4.26
4.51
e12/l
18.62
616
5919
7
25
2.82
1.65
1.7
1.3
—
—
—
0
0
10
43
2.35
1.59
1.3
1.1
—
—
—
0
0
7
28
2.52
1.45
1.1
2.1
—
—
—
0
0
6
22
2.74
1.43
1.2
1.2
133.97
165.90
iu/ml
—
6
22
569
5471
1.27
1.41
5.3
4.9
2.45
2.74
mmol/l
12.55
526
5067
6
23
2.62
1.37
3.3
3.1
229.67
208.26
u/l
—
6
23
6
23
2.62
1.37
1.3
1.3
—
—
—
0
0
29
191
1.54
1.37
1.3
1.3
36.53
22.76
iu/l
1.11
24
162
26
170
1.55
1.28
2.1
2.3
124.17
3597.02
u/l
—
10
63
8
36
2.24
1.24
2.9
2.1
21.32
61.59
u/ml
—
8
36
558
5374
1.23
1.22
4.9
4.4
4.23
4.62
mmol/l
15.53
518
5002
49
369
1.35
1.18
1.2
1.2
137.22
144.31
iu/ml
0.03
16
153
14
79
1.79
1.17
1.3
1.4
0.26
0.40
nmol/l
—
9
62
11
57
1.95
1.17
1.6
1.4
24.76
26.34
u/l
0.05
11
47
5
20
2.51
1.15
1.6
1.2
—
—
—
0
0
5
20
2.51
1.15
2.4
3.2
40120.00
41135.00
ug/l
—
5
20
16
95
1.70
1.14
1.8
1.7
—
—
—
0
0
553
5338
1.21
1.08
4.9
4.3
1.26
1.45
mmol/l
19.84
506
4948
10
52
1.94
1.06
1.5
1.1
—
—
—
0
0
13
78
1.68
0.92
1.2
1.1
—
—
—
0
0
15
94
1.61
0.91
2.1
1.7
—
—
—
0
0
6
29
2.08
0.89
2.2
1.3
—
—
—
0
0
6
31
1.94
0.84
1.2
2.0
—
—
—
0
0
8
48
1.67
0.79
2.3
1.1
—
—
—
0
0
7
38
1.85
0.73
1.1
1.7
—
—
—
0
0
5
27
1.86
0.68
2.4
2.3
—
—
—
0
0
78
672
1.18
0.67
14.0
7.3
—
—
—
0
0
106
941
1.15
0.64
1.5
1.5
—
—
—
0
0
8
49
1.64
0.62
2.3
1.2
—
—
—
0
0
9
63
1.43
0.52
1.0
1.2
—
—
—
0
0
75
664
1.15
0.49
4.9
4.4
32.31
31.80
%
0.14
54
461
28
227
1.24
0.47
1.5
1.5
—
—
—
0
0
11
153
0.71
0.46
1.7
1.5
—
—
—
0
0
27
224
1.21
0.39
1.7
1.6
—
—
—
0
0
5
36
1.39
0.38
19.0
16.3
885.00
1507.56
nmol/l
—
5
36
5
79
0.63
0.35
4.6
2.9
27.60
18.58
u/ml
—
5
79
31
264
1.18
0.35
1.1
1.0
—
—
—
0
0
10
74
1.36
0.32
1.2
1.1
—
—
—
0
0
22
191
1.16
0.22
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
23.34
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
32
291
1.10
0.17
2.0
1.7
—
—
—
0
0
10
82
1.22
0.17
1.7
1.5
—
—
—
0
0
154
1592
0.96
0.16
4.0
4.3
22.07
21.46
%
0.17
74
764
71
749
0.94
0.16
1.4
1.4
—
—
—
0
0
13
151
0.86
0.16
1.2
1.4
—
—
—
0
0
56
528
1.07
0.14
1.6
1.8
—
—
—
0
0
61
579
1.06
0.13
2.0
1.9
—
—
—
0
0
13
114
1.14
0.12
3.7
3.8
47.17
29.18
mg/l
—
7
74
19
175
1.09
0.08
1.7
1.7
42.05
40.42
nmol/l
0.09
19
168
147
1441
1.03
0.08
1.7
1.6
1.92
1.38
mmol/l
1.98
132
1221
8
78
1.03
0.07
1.0
1.1
—
1.19
—
0
37
17
157
1.08
0.07
2.4
2.3
89.64
87.26
ug/min
0.02
11
95
15
163
0.92
0.07
1.5
1.5
—
—
—
0
0
196
1980
0.99
0.04
4.9
4.9
4.18
2.89
ug/l
0.46
173
1784
12
128
0.94
0.02
2.2
1.9
146.67
222.82
pmol/l
1.51
12
120
12
113
1.06
0.02
1.8
1.6
—
—
—
0
0
14
133
1.05
0.01
1.4
1.6
—
—
—
0
0
13
124
1.05
0.00
1.3
1.5
—
—
—
0
0
13
124
1.05
0.00
1.3
1.5
—
—
—
0
0
13
124
1.05
0.00
1.3
1.5
—
—
—
0
0
13
124
1.05
0.00
1.3
1.5
—
—
—
0
0
15
146
1.03
0.00
1.0
1.1
—
1.86
—
0
18
115
1146
1.00
0.00
2.7
2.9
0.75
0.77
ug/l
0.09
75
756
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
-0.00
2.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
11.60
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_SPLEENDISEASE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SPLEENDISEASE | 3.971 [3.07, 5.14] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.19 |
During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 1386 females with D3_SPLEENDISEASE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SPLEENDISEASE | 3.698 [2.92, 4.68] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 499 out of 1462 males with D3_SPLEENDISEASE died.
Mortality risk
Mortality risk for people of age
years, who have D3_SPLEENDISEASE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.481% | 0.759% |
| 5 | 2.249% | 4.089% |
| 10 | 5.579% | 10.28% |
| 15 | 10.302% | 19.424% |
| 20 | 17.274% | 31.076% |
Relationships between endpoints
↥Index endpoint: D3_SPLEENDISEASE – Diseases of spleen
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data