Cervical root disorders

G6_CERVROOT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G54.2
  • Hospital discharge: ICD-9 3532
  • Cause of death: ICD-10 G54.2
  • Cause of death: ICD-9 3532

2 out of 7 registries used, show all original rules.

255

4. Check minimum number of events

None

255

5. Include endpoints

None

255

6. Filter based on genotype QC (FinnGen only)

248

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G54
Name in latin
Morbositates radicum nervorum cervicalium non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1967 895 1060
Only index persons 1814 845 969
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.04
Median age at first event (years)
Whole population 53.07 52.51 53.45
Only index persons 52.39 51.91 52.81

-FinnGen-

Key figures

All Female Male
Number of individuals 248 127 121
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 53.55 51.93 55.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
255
Matched controls
2550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G54.2
ICD-10 Finland
Cervical root disorders, not elsewhere classified
+∞
277.4
213
*
XA402
NOMESCO Finland
ENMG
116.9
192.5
100
14
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
33.4
110.6
76
32
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
14.1
68.9
72
69
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
25.8
61.8
45
21
G56.0
ICD-10 Finland
Carpal tunnel syndrome
20.0
59.7
49
30
N03AX16
ATC
[U] pregabalin
6.2
46.0
120
320
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
12.9
44.9
47
44
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
6.2
43.0
103
252
3532A
ICD-9 Finland
Nerve root and plexus disorders, Cervical root lesions, not elsewhere classified
+∞
42.9
40
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
14.6
42.8
41
33
M54.2
ICD-10 Finland
Cervicalgia
7.0
33.5
59
105
G54.0
ICD-10 Finland
Brachial plexus disorders
80.6
31.8
35
5
M53.1
ICD-10 Finland
Cervicobrachial syndrome
5.9
31.4
68
148
N03AX12
ATC
[U] gabapentin; oral
4.6
25.0
74
207
G56.2
ICD-10 Finland
Lesion of ulnar nerve
92.1
23.1
25
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
4.3
21.4
67
194
M47.9
ICD-10 Finland
Spondylosis, unspecified
18.1
20.7
32
20
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
114.0
19.9
21
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
19.9
56
149
ACC51
NOMESCO Finland
Release of median nerve
216.1
19.8
20
*
N02AX02
ATC
tramadol; systemic, rectal
3.3
19.2
148
759
N06AA09
ATC
amitriptyline; systemic
4.9
18.8
46
109
M54.4
ICD-10 Finland
Lumbago with sciatica
3.7
17.9
70
235
K29
ICPC
Cardiovascular sympt/complt other
7.7
17.7
26
37
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
96.5
16.8
18
*
L01
ICPC
Neck symptom/complaint
3.7
15.7
58
186
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.7
15.7
60
197
M48.0
ICD-10 Finland
Spinal stenosis
4.1
15.5
49
141
M50.3
ICD-10 Finland
Other cervical disc degeneration
17.9
15.1
23
14
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
60.4
15.0
17
*
M54.1
ICD-10 Finland
Radiculopathy
6.7
14.5
24
39
Z01.9
ICD-10 Finland
Special examination, unspecified
5.1
14.2
32
70
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
21.6
14.0
20
10
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.7
13.9
35
84
Z50.1
ICD-10 Finland
Other physical therapy
5.1
12.9
29
63
N02BF01
ATC
gabapentin; oral
4.4
12.9
35
89
M54.5
ICD-10 Finland
Low back pain
2.6
12.7
111
576
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
11.8
140
832
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.4
11.6
31
78
M03BX02
ATC
tizanidine; oral
2.7
11.6
182
1229
L28
ICPC
Limited function/disability (L)
3.1
11.6
58
223
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.6
10.8
39
122
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
10.6
129
765
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
114.5
10.5
11
*
N06AX21
ATC
duloxetine; oral
3.3
10.0
41
139
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
5.0
10.0
22
47
M79.0
ICD-10 Finland
Rheumatism, unspecified
10.2
9.9
19
20
A29
ICPC
General symptom/complaint other
3.1
9.9
46
168
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
5.1
9.7
21
44
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
9.7
81
403
M01AX17
ATC
nimesulide; oral
2.5
9.4
76
371
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.8
9.4
30
86
M25.5
ICD-10 Finland
Pain in joint
2.3
9.3
96
522
XA420
NOMESCO Finland
Extensive sleep examination
14.4
9.3
15
11
L03
ICPC
Low back symptom/complaint
2.4
9.1
78
390
M01AH05
ATC
etoricoxib; oral
2.4
9.1
177
1251
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.2
9.0
40
142
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
14.7
8.8
14
10
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.9
8.8
45
174
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
17.0
8.6
13
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
8.6
101
578
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
8.4
40
148
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
34.5
8.1
10
*
A02BC02
ATC
pantoprazole; systemic
2.3
8.1
185
1363
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.3
8.1
78
409
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
8.1
22
56
WX704
NOMESCO Finland
Intubation
3.8
7.9
25
71
A02BC05
ATC
esomeprazole; systemic
2.1
7.8
115
712
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
7.5
7.6
17
24
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
7.5
30
100
G55.2
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
82.4
7.5
8
*
G54.4
ICD-10 Finland
Lumbosacral root disorders, not elsewhere classified
82.4
7.5
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
7.4
65
326
M54.8
ICD-10 Finland
Other dorsalgia
6.6
7.4
18
29
M79.6
ICD-10 Finland
Pain in limb
2.1
7.3
114
717
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
16.3
7.3
11
7
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.2
7.1
70
368
S29
ICPC
Skin symptom/complaint other
2.4
7.1
55
261
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
7.0
29
99
M65.3
ICD-10 Finland
Trigger finger
4.5
6.9
17
40
K30
ICD-10 Finland
Functional dyspepsia
2.8
6.7
37
148
M01AC06
ATC
meloxicam; systemic, rectal
2.0
6.7
105
658
XG405
NOMESCO Finland
Education on PEF monitoring
10.4
6.6
12
12
R43
ICPC
Respiratory, Other diagnostic procedure
10.4
6.6
12
12
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
6.5
42
182
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
6.5
57
285
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.3
6.5
17
42
KMAK, ,
NOMESCO Finland
1.9
6.4
135
933
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
9.6
6.4
12
13
R42
ICD-10 Finland
Dizziness and giddiness
2.2
6.3
65
346
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.3
6.3
14
20
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
18.6
6.3
9
5
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.7
6.3
20
57
N02BF02
ATC
pregabalin; oral
3.5
6.3
22
67
G51.0
ICD-10 Finland
Bell palsy
+∞
6.3
6
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
6.2
22
68
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
3.7
6.1
20
58
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
6.1
23
74
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
6.0
81
477
R2110
NOMESCO Finland
Giving the first information
3.5
6.0
21
64

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
41
6.95
16.16
1.8
1.8
—
—
—
0
0
30
71
4.66
12.10
1.9
1.8
—
—
—
0
0
32
86
4.11
10.97
2.5
3.4
—
—
—
0
0
87
525
2.00
6.04
5.1
7.5
—
—
—
0
0
30
117
2.77
5.70
2.3
2.3
—
—
—
0
0
113
775
1.82
5.14
1.9
1.9
90.74
94.85
pmol/l
0.47
60
395
111
778
1.76
4.55
2.8
3.4
25.56
35.97
ng/l
0.61
74
536
128
938
1.73
4.46
9.4
11.5
1.07
1.24
inr
2.10
25
271
56
329
1.90
4.04
1.3
1.2
33.71
33.80
iu/ml
0.00
27
107
60
366
1.84
3.84
3.1
3.5
133.18
159.43
ng/l
0.09
51
293
53
825
0.55
3.71
2.5
2.7
—
—
—
0
0
179
1508
1.63
3.13
4.3
4.0
9.19
11.51
mm/h
2.66
173
1392
51
315
1.77
3.11
1.2
1.2
33.15
12.94
u/ml
0.35
17
128
67
450
1.66
3.02
1.6
1.6
23.34
20.38
nmol/l
0.41
60
385
133
1054
1.55
2.97
4.7
6.3
0.19
0.19
e9/l
0.13
121
924
116
896
1.54
2.88
4.7
5.7
1.23
1.21
mmol/l
1.47
110
823
123
966
1.53
2.81
4.9
5.8
54.32
57.51
%
2.17
118
910
146
1197
1.51
2.68
6.3
10.2
4.05
4.04
e9/l
0.02
135
1046
128
1023
1.50
2.64
4.7
5.9
0.57
0.58
e9/l
0.19
117
881
128
1024
1.50
2.63
4.7
5.9
0.04
0.04
e9/l
1.11
117
882
129
1040
1.49
2.51
4.7
5.9
1.96
1.95
e9/l
0.02
121
918
202
1795
1.60
2.42
16.4
17.5
332.10
332.82
g/l
0.51
202
1789
178
1540
1.52
2.39
3.6
3.8
14.88
14.83
pmol/l
0.08
164
1387
5
8
6.35
2.38
1.2
1.4
28.20
34.38
umol/l
—
5
8
42
267
1.69
2.31
1.3
1.2
—
—
—
0
0
26
143
1.91
2.29
2.2
2.5
—
18.91
—
0
9
72
530
1.50
2.14
3.2
3.7
91.61
92.05
%
0.05
67
516
24
133
1.89
2.08
1.0
1.2
—
—
—
0
0
7
20
3.57
2.07
1.1
1.1
—
—
—
0
0
119
973
1.42
2.02
6.2
6.7
1.23
1.21
mmol/l
0.97
109
837
118
970
1.40
1.91
4.9
6.3
—
—
—
0
0
233
2180
1.80
1.89
13.6
12.2
—
—
—
0
0
157
1367
1.39
1.75
4.1
3.8
—
—
—
0
0
11
48
2.35
1.73
1.3
1.1
—
—
—
0
0
11
49
2.30
1.66
1.3
1.1
—
—
—
0
0
11
49
2.30
1.66
1.3
1.1
—
—
—
0
0
57
421
1.46
1.64
1.1
1.2
0.47
1.43
u/ml
1.47
13
131
43
593
0.67
1.61
2.0
1.7
1.35
1.39
mmol/l
0.21
38
497
8
167
0.46
1.53
3.3
3.5
—
—
—
0
0
76
601
1.38
1.49
3.1
3.9
7.41
7.40
ph
—
6
118
205
1889
1.43
1.48
4.5
4.4
1.78
2.55
mu/l
0.63
196
1717
7
28
2.54
1.46
1.0
1.0
—
—
—
0
0
25
377
0.63
1.42
4.8
2.7
521.63
546.69
mosm/kgh2o
0.22
19
323
58
443
1.40
1.39
1.6
1.8
1.97
1.25
mg/l
0.56
46
353
9
41
2.24
1.38
1.2
1.1
—
—
—
0
0
12
219
0.53
1.37
1.5
1.5
—
—
—
0
0
220
2063
1.48
1.36
14.2
13.5
19.45
24.64
mg/l
1.42
190
1613
10
47
2.17
1.35
1.3
1.1
—
—
—
0
0
74
595
1.34
1.30
2.4
3.1
2338.77
51.18
mg/l
0.80
41
389
60
468
1.37
1.27
2.1
3.4
—
—
—
0
0
169
1529
1.31
1.24
3.6
3.6
—
—
—
0
0
8
39
2.08
1.16
2.9
5.5
—
—
—
0
0
5
20
2.53
1.15
1.4
1.2
—
—
—
0
0
7
140
0.49
1.13
1.1
1.5
—
—
—
0
0
7
31
2.29
1.11
3.7
2.2
—
—
—
0
0
5
21
2.41
1.09
1.0
1.5
51.90
17.67
ug/l
—
5
21
234
2245
1.51
1.02
16.5
15.8
78.09
76.64
umol/l
0.23
234
2245
98
844
1.26
1.00
1.7
2.1
—
—
—
0
0
113
990
1.25
1.00
3.1
3.3
0.00
0.00
estimate
-0.00
15
188
0
29
0.00
0.98
0.0
1.5
—
—
—
0
0
9
50
1.83
0.97
1.3
1.2
—
—
—
0
0
221
2103
1.38
0.97
4.4
4.4
4.52
4.73
mmol/l
2.62
211
1963
216
2050
1.35
0.95
4.6
4.5
6.12
5.97
mmol/l
0.91
206
1904
74
623
1.26
0.91
2.6
3.0
7.98
7.72
mmol/l
0.21
66
518
112
989
1.24
0.90
4.1
4.4
0.00
0.00
estimate
-0.00
14
173
240
2325
1.55
0.86
19.9
19.8
4.55
4.51
e12/l
0.55
235
2262
5
98
0.50
0.79
1.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
28
212
1.36
0.74
4.9
8.3
1.11
1.21
mmol/l
0.06
21
180
223
2144
1.32
0.73
4.9
4.9
2.70
2.80
mmol/l
1.05
214
1992
5
25
2.02
0.73
1.4
2.9
—
—
—
0
0
11
68
1.65
0.73
1.0
1.1
—
—
—
0
0
239
2323
1.46
0.72
19.4
19.8
40.98
40.51
%
0.65
228
2199
7
41
1.73
0.70
4.7
1.2
—
—
—
0
0
31
241
1.33
0.70
1.6
1.4
421.82
425.96
titre
0.01
11
57
111
1000
1.19
0.69
3.1
3.3
0.00
0.04
estimate
0.80
14
168
212
2029
1.27
0.69
3.7
4.0
1.32
1.29
mmol/l
0.26
201
1873
5
27
1.87
0.69
1.6
1.2
—
—
—
0
0
54
455
1.24
0.66
1.9
1.9
1.93
3.12
mg/l
6.80
46
394
19
138
1.41
0.64
1.2
1.4
—
—
—
0
0
207
1983
1.23
0.62
5.3
5.5
40.53
39.74
mmol/mol
0.63
198
1854
62
534
1.21
0.62
3.4
4.3
—
—
—
0
0
45
535
0.81
0.62
4.0
3.6
0.00
0.00
estimate
-0.00
13
169
72
631
1.20
0.60
3.0
3.5
2.85
8.15
mg/mmol
1.91
39
394
28
351
0.77
0.60
1.6
1.7
1185.29
1247.73
nmol/l
0.14
21
264
0
22
0.00
0.59
0.0
1.5
—
38785.45
—
0
11
0
23
0.00
0.58
0.0
1.4
—
885.43
—
0
14
12
172
0.68
0.58
1.2
1.3
—
—
—
0
0
40
331
1.25
0.58
3.1
2.8
2.20
2.27
e6/l
0.03
30
176
12
81
1.51
0.58
1.1
1.1
—
—
—
0
0
29
232
1.28
0.55
1.3
1.3
—
—
—
0
0
46
391
1.22
0.53
1.4
1.7
448.37
12422800.15
pmol/l
0.50
40
322
7
45
1.57
0.49
4.6
1.1
3.13
3.82
mmol/l
—
7
40
45
385
1.21
0.49
1.3
1.4
2.25
2.68
g/l
1.02
29
248
26
209
1.27
0.49
1.3
1.6
—
—
—
0
0
10
68
1.49
0.47
1.5
1.5
—
—
—
0
0
16
120
1.36
0.47
1.2
1.2
183.49
128.55
iu/ml
—
7
55
103
947
1.15
0.47
7.0
8.8
0.00
0.00
e9/l
0.56
93
758
8
120
0.66
0.46
1.0
1.3
—
—
—
0
0
63
704
0.86
0.45
4.3
3.6
163.37
111.12
e6/l
0.18
44
493
5
31
1.62
0.43
3.4
2.9
—
—
—
0
0
12
87
1.40
0.43
2.8
3.8
25.67
24.04
mmol/l
1.19
12
87
8
56
1.44
0.43
2.5
3.1
—
—
—
0
0
215
2088
1.19
0.42
4.2
4.4
1.42
1.48
mmol/l
1.15
206
1938
0
15
0.00
0.41
0.0
1.0
—
33.69
—
0
15
0
16
0.00
0.41
0.0
1.4
—
7.64
—
0
16
73
662
1.14
0.40
2.7
3.6
2.37
2.36
mmol/l
0.25
66
592
0
18
0.00
0.40
0.0
1.0
—
254.50
—
0
10
0
18
0.00
0.40
0.0
12.7
—
1013.28
—
0
18
0
18
0.00
0.40
0.0
15.7
—
1879.50
—
0
18
0
19
0.00
0.39
0.0
3.1
—
43.89
—
0
13
0
19
0.00
0.39
0.0
2.5
—
33.05
—
0
19
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
94
872
1.12
0.36
3.1
4.4
37.01
35.88
g/l
1.40
87
819
15
117
1.30
0.36
1.2
2.5
—
—
—
0
0
9
125
0.71
0.36
2.0
1.5
—
—
—
0
0
5
80
0.62
0.36
6.0
8.8
—
—
—
0
0
17
137
1.26
0.33
2.3
2.8
147.12
189.82
ng/l
0.27
17
125
10
74
1.37
0.33
3.0
2.3
—
—
—
0
0
12
153
0.77
0.31
3.2
3.1
—
—
—
0
0
7
52
1.36
0.31
4.6
1.2
526.57
457.91
mg/l
—
7
47
20
169
1.20
0.26
1.9
2.7
3.84
7.38
ug/l
1.23
15
151
28
245
1.16
0.26
1.3
1.5
—
—
—
0
0
69
645
1.10
0.23
2.1
2.3
—
—
—
0
0
24
210
1.16
0.22
1.6
2.1
32.44
29.99
u/l
0.17
18
171
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
8
104
0.76
0.21
1.5
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
1585.00
—
0
10
0
12
0.00
0.21
0.0
8.4
—
7.45
—
0
5
24
271
0.87
0.21
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
185.59
—
0
13
51
549
0.91
0.20
2.7
3.0
0.28
0.41
e6/l
0.45
39
403
31
279
1.13
0.20
1.5
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
11.62
—
0
14
50
538
0.91
0.20
2.1
2.9
—
—
—
0
0
10
122
0.81
0.19
1.3
1.6
—
—
—
0
0
33
300
1.11
0.19
2.2
1.8
—
—
—
0
0
18
206
0.86
0.19
1.4
1.4
—
—
—
0
0
7
59
1.19
0.18
1.1
1.1
—
—
—
0
0
23
205
1.13
0.17
1.3
1.5
—
—
—
0
0
42
452
0.92
0.17
2.2
2.8
0.66
0.79
ug/l
0.65
28
294
58
546
1.08
0.17
1.3
1.4
—
—
—
0
0
58
546
1.08
0.17
3.6
2.8
—
—
—
0
0
146
1422
1.06
0.16
3.3
3.0
66.80
48.92
u/l
0.38
141
1326
9
79
1.14
0.15
1.7
3.8
—
—
—
0
0
23
209
1.11
0.13
2.2
1.5
—
—
—
0
0
11
95
1.17
0.12
2.1
2.8
—
—
—
0
0
12
105
1.15
0.11
1.2
1.2
1084.88
133.68
u/ml
0.72
12
95
14
126
1.12
0.09
1.1
1.2
—
—
—
0
0
6
57
1.05
0.08
1.7
1.4
—
—
—
0
0
27
285
0.94
0.07
2.1
2.2
13.06
13.44
umol/l
0.11
27
270
8
93
0.86
0.07
4.9
10.8
—
—
—
0
0
13
119
1.10
0.06
2.5
4.2
—
—
—
0
0
58
596
0.97
0.05
3.4
3.1
22.04
166.03
e6/l
0.72
43
453
16
149
1.08
0.05
3.7
4.8
0.00
0.22
%
—
6
46
25
238
1.06
0.05
1.4
1.4
—
—
—
0
0
16
171
0.93
0.05
3.7
4.7
0.67
0.93
%
—
6
68
25
261
0.95
0.04
2.0
2.1
2.41
2.38
g/l
0.12
25
243
14
149
0.94
0.03
2.9
4.7
0.67
0.54
%
—
6
52
79
801
0.98
0.03
2.4
3.1
5.56
5.80
ph
—
9
82
15
158
0.95
0.02
3.9
4.8
0.00
0.16
%
—
6
55
16
153
1.05
0.01
6.8
9.2
—
—
—
0
0
18
187
0.96
0.01
6.0
3.8
—
—
—
0
0
57
564
1.01
0.00
3.5
2.7
—
—
—
0
0
26
261
1.00
0.00
3.3
7.3
104.92
103.86
mmol/l
0.73
26
261
24
243
0.99
0.00
1.9
2.3
243.44
135.24
ug/g
0.52
19
194
21
214
0.98
0.00
1.5
1.6
—
—
—
0
0
58
585
0.99
0.00
3.6
3.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
9
98
0.92
-0.00
1.2
2.4
1.16
1.36
%
—
9
98
0
8
0.00
-0.00
0.0
2.0
—
1839.38
—
0
8
0
8
0.00
-0.00
0.0
2.4
—
5.98
—
0
8
0
7
0.00
-0.00
0.0
4.1
—
49.43
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
3.28
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.8
39.06
38.38
g/l
—
5
46
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
96
0.94
-0.00
1.2
2.4
0.67
0.66
%
—
9
96
9
95
0.95
-0.00
1.2
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1.21
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_CERVROOT and mortality.

Females

Parameter HR [95% CI] p-value
G6_CERVROOT 1.156 [0.87, 1.54] 0.324
Birth year 0.996 [0.99, 1.0] 0.362

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 666 females with G6_CERVROOT died.

Males

Parameter HR [95% CI] p-value
G6_CERVROOT 1.369 [1.08, 1.73] 0.009
Birth year 0.985 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 773 males with G6_CERVROOT died.

Mortality risk

Mortality risk for people of age

years, who have G6_CERVROOT.

N-year risk Females Males
1 0.088% 0.23%
5 0.607% 1.299%
10 1.623% 3.363%
15 3.355% 6.757%
20 5.694% 11.257%

Relationships between endpoints

Index endpoint: G6_CERVROOT – Cervical root disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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