Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist

M13_CHRONSYNOVITISHANDWRIST

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.0, M70.1, M77.2
  • Hospital discharge: ICD-9 7264A
  • Cause of death: ICD-10 M70.0, M70.1, M77.2
  • Cause of death: ICD-9 7264A

2 out of 7 registries used, show all original rules.

542

4. Check minimum number of events

None

542

5. Include endpoints

None

542

6. Filter based on genotype QC (FinnGen only)

524

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3653 2118 1522
Only index persons 3478 2036 1442
Unadjusted period prevalence (%)
Whole population 0.05 0.06 0.04
Only index persons 0.07 0.07 0.06
Median age at first event (years)
Whole population 51.39 52.07 50.41
Only index persons 50.83 51.70 49.59

-FinnGen-

Key figures

All Female Male
Number of individuals 524 347 177
Unadjusted period prevalence (%) 0.11 0.12 0.08
Median age at first event (years) 52.14 51.86 52.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
542
Matched controls
5420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
3207.0
307.7
349
*
M70.1
ICD-10 Finland
Bursitis of hand
691.9
116.7
111
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
47.8
81.2
48
11
M77.2
ICD-10 Finland
Periarthritis of wrist
+∞
79.1
74
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
24.9
74.9
54
24
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
19.0
67.9
55
32
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
181.0
62.4
64
*
M79.6
ICD-10 Finland
Pain in limb
4.2
61.2
285
1123
G56.0
ICD-10 Finland
Carpal tunnel syndrome
5.5
58.8
137
314
M65.3
ICD-10 Finland
Trigger finger
13.4
58.2
57
47
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.6
55.3
168
478
M25.5
ICD-10 Finland
Pain in joint
3.6
45.6
241
991
N03AX16
ATC
[U] pregabalin
3.8
43.5
178
617
N02AX02
ATC
tramadol; systemic, rectal
3.3
42.0
288
1374
M67.4
ICD-10 Finland
Ganglion
8.1
39.7
56
76
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
16.4
39.4
34
22
M70.6
ICD-10 Finland
Trochanteric bursitis
4.5
38.5
108
283
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.2
37.4
86
191
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
8.1
37.1
52
70
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
9.6
33.7
41
46
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
8.1
33.6
47
63
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
11.3
33.4
36
34
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.0
29.7
95
272
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.3
29.3
63
131
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
29.2
279
1512
N06AX21
ATC
duloxetine; oral
4.1
28.8
90
253
N03AX12
ATC
[U] gabapentin; oral
3.5
28.4
114
380
M54.4
ICD-10 Finland
Lumbago with sciatica
3.3
27.2
123
441
M77.1
ICD-10 Finland
Lateral epicondylitis
5.1
27.1
61
132
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
26.9
161
679
M01AC06
ATC
meloxicam; systemic, rectal
2.7
26.8
241
1254
M54.5
ICD-10 Finland
Low back pain
2.7
26.2
224
1134
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
26.1
227
1158
NDL52
NOMESCO Finland
Tenosynovectomy of hand
76.2
26.0
29
*
M13.9
ICD-10 Finland
Arthritis, unspecified
4.7
24.9
62
146
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.1
24.7
74
201
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.4
24.4
103
353
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
70.8
24.0
27
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.2
23.7
69
183
ZXA00
NOMESCO Finland
Right side
2.7
23.2
173
810
P01BA02
ATC
hydroxychloroquine; oral
4.0
22.5
69
190
M01AH05
ATC
etoricoxib; oral
2.5
22.0
368
2479
M01AX17
ATC
nimesulide; oral
2.7
21.9
158
725
M70.2
ICD-10 Finland
Olecranon bursitis
8.1
21.9
30
39
M01AE03
ATC
ketoprofen; systemic, rectal
2.4
21.6
230
1266
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.4
21.5
85
278
M01AE02
ATC
naproxen; oral, rectal
2.4
21.3
342
2246
N06AA09
ATC
amitriptyline; systemic
3.7
21.1
73
219
ZXA05
NOMESCO Finland
Left side
2.6
20.5
154
718
J01AA02
ATC
doxycycline; systemic
3.0
20.4
459
3496
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
20.3
245
1414
M48.0
ICD-10 Finland
Spinal stenosis
3.4
19.9
80
264
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
19.7
182
932
L08
ICPC
Shoulder symptom/complaint
2.7
19.6
126
543
M77.9
ICD-10 Finland
Enthesopathy, unspecified
7.8
19.3
27
36
H02AB06
ATC
prednisolone; systemic
2.3
19.3
281
1746
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
57.2
19.1
22
*
J01FF01
ATC
clindamycin; systemic
2.4
18.9
175
896
L04AX03
ATC
methotrexate; systemic
3.4
18.8
75
246
M79.7
ICD-10 Finland
Fibromyalgia
14.9
18.8
31
22
A01
ICPC
Pain general/multiple sites
3.7
18.7
63
185
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
18.7
64
190
M01AH01
ATC
celecoxib; oral
2.7
18.7
119
509
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.4
18.6
48
116
R51.80
ICD-10 Finland
Headache
2.9
18.5
102
404
M01AB05
ATC
diclofenac; systemic, rectal
2.4
18.5
385
2751
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
18.3
136
628
G44.2
ICD-10 Finland
Tension-type headache
3.0
18.1
92
349
S18
ICPC
Laceration/cut
2.2
18.0
264
1630
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
4.3
18.0
48
119
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.9
17.6
55
153
A02BC02
ATC
pantoprazole; systemic
2.3
17.6
386
2790
NF1AA
NOMESCO Finland
Hip X-ray examination
3.6
17.4
60
179
J01DB01
ATC
cefalexin; oral
2.9
17.3
466
3682
ACC51
NOMESCO Finland
Release of median nerve
3.9
17.2
54
151
J01DA01
ATC
[U] cefalexin
2.2
16.5
354
2506
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.4
16.4
43
105
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.1
16.1
76
275
M02AA07
ATC
piroxicam; topical
2.2
16.0
207
1203
A07EC01
ATC
sulfasalazine; oral, rectal
3.5
15.9
57
174
SPAT1202
SPAT
Intra-articular injection
6.1
15.9
28
48
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
15.8
165
878
A02BC05
ATC
esomeprazole; systemic
2.1
15.8
235
1440
M79.1
ICD-10 Finland
Myalgia
2.9
15.5
81
311
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
15.2
297
2004
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
15.0
161
864
C03CA01
ATC
furosemide; systemic
2.2
14.9
161
866
M02AA10
ATC
ketoprofen; topical
2.5
14.7
102
452
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
14.6
145
753
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
14.5
129
640
L11
ICPC
Wrist symptom/complaint
3.3
14.4
58
191
A02BC03
ATC
lansoprazole; oral
2.2
14.4
173
970
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
14.3
61
208
N02BE01
ATC
paracetamol; systemic, rectal
3.2
14.2
495
4155
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
14.2
107
492
R60.0
ICD-10 Finland
Localized oedema
2.9
14.2
75
289
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
43.7
14.2
17
*
M01AX05
ATC
glucosamine; oral
2.3
14.0
121
591
R03AC02
ATC
salbutamol; inhalant
2.0
14.0
311
2172
M01AH02
ATC
rofecoxib; oral
2.7
14.0
81
327
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
18.2
13.9
21
12
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
13.9
50
153
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
13.9
70
263
N06AX16
ATC
venlafaxine; oral
2.6
13.7
92
400
A02BC01
ATC
omeprazole; systemic
2.2
13.7
158
869
M70.7
ICD-10 Finland
Other bursitis of hip
5.8
13.5
25
45
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.4
13.3
49
152
R42
ICD-10 Finland
Dizziness and giddiness
2.2
13.3
132
682
M01AX01
ATC
nabumetone; oral
4.5
13.3
33
77
M09AX01
ATC
hyaluronic acid; parenteral
4.2
13.3
36
90
M54.3
ICD-10 Finland
Sciatica
3.7
13.2
43
123
M03BX02
ATC
tizanidine; oral
2.0
13.2
353
2610
J01DA09
ATC
[U] cefadroxil
2.1
13.1
160
897
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.4
13.1
26
50
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.8
13.0
71
278
N02BF02
ATC
pregabalin; oral
3.9
12.8
38
102
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
12.7
245
1614
H02AB04
ATC
methylprednisolone; systemic
2.5
12.7
89
395
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
12.6
261
1760
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
12.5
47
148
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.3
12.3
25
49
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.9
12.2
306
2189
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.4
12.1
24
46
Z3226
NOMESCO Finland
Physiotherapist
2.3
12.1
106
519
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.0
12.1
57
206
UJF32
NOMESCO Finland
Coloscopy
2.1
12.0
148
830
J01FA06
ATC
roxithromycin; oral
1.9
11.8
224
1457
K30
ICD-10 Finland
Functional dyspepsia
2.6
11.7
73
305
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.7
11.7
70
287
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
11.6
43
134
SPAT1153
SPAT
Removal of sutures
2.0
11.5
175
1055
S80.0
ICD-10 Finland
Contusion of knee
3.1
11.5
50
172
R4120
NOMESCO Finland
Occupational therapy
3.3
11.5
44
140
H02AB07
ATC
prednisone; oral
2.4
11.5
83
373
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.2
11.2
46
153
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
11.2
152
880
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
11.0
385
3020
A02BA04
ATC
nizatidine; systemic
3.0
11.0
51
182
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.1
11.0
123
662
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.4
11.0
84
387
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
5.6
11.0
21
39
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.4
10.9
28
67
M01AB55
ATC
diclofenac, combinations; oral
3.2
10.9
45
150
L86
ICPC
Back syndrome with radiating pain
3.5
10.9
38
114
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
10.9
62
248
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
10.9
128
703
WX204
NOMESCO Finland
Axillary plexus blockaced
4.6
10.8
26
59
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.8
10.8
34
95
P03
ICPC
Feeling depressed
2.8
10.7
56
214
L15
ICPC
Knee symptom/complaint
2.0
10.6
133
746
A07AA02
ATC
nystatin; oral
3.4
10.6
39
121
AA1AD
NOMESCO Finland
CT of head and brain
2.0
10.6
141
808
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
10.6
59
233
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
10.3
10.6
20
20
N06AX11
ATC
mirtazapine; oral
1.9
10.6
189
1197
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.8
10.5
33
92
7264A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of wrist and carpus
+∞
10.4
10
*
9502
FHL
Tendon splitting (De Quervain, click finger)
+∞
10.4
10
*
M19.9
ICD-10 Finland
Arthrosis, unspecified
4.2
10.3
28
70
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
10.3
86
411
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
10.3
103
531
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
10.3
29
75
M01AH03
ATC
valdecoxib; oral
3.3
10.2
40
129
N02AA05
ATC
oxycodone; systemic
2.2
10.2
92
454
J01MA02
ATC
ciprofloxacin; systemic
1.8
10.2
206
1353
R52.2
ICD-10 Finland
Other chronic pain
4.4
10.2
26
62
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
10.2
106
554
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.9
10.1
22
46
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.9
10.1
22
46
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
10.1
49
180
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
10.0
161
982
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.9
10.0
30
81
L03
ICPC
Low back symptom/complaint
2.0
10.0
142
831
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
10.0
102
529
X58
ICD-10 Finland
Exposure to other specified factors
2.4
9.9
77
356
R96
ICPC
Asthma
2.6
9.9
60
247
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.0
9.9
20
23
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
26.6
9.8
13
5
M70.4
ICD-10 Finland
Prepatellar bursitis
10.9
9.8
18
17
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
9.8
160
979
M71.1
ICD-10 Finland
Other infective bursitis
56.0
9.7
11
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.2
9.6
20
40
A10AA01, ,
ATC
4.6
9.6
23
52
M54.6
ICD-10 Finland
Pain in thoracic spine
2.9
9.6
47
173
R53
ICD-10 Finland
Malaise and fatigue
2.0
9.5
126
719
L13
ICPC
Hip symptom/complaint
2.1
9.5
96
496
A10AB01
ATC
insulin (human); parenteral
4.1
9.4
26
66
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
9.4
375
2988
H04AA01
ATC
glucagon; nasal, parenteral
8.9
9.4
19
22
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
4.2
9.3
25
62
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
7.5
9.3
21
29
SPAT1255
SPAT
Intravenous administration of medicine
3.1
9.3
40
137
M43.1
ICD-10 Finland
Spondylolisthesis
3.8
9.3
28
76
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
9.2
218
1490
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.4
9.2
69
314
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.7
9.2
50
195
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
9.2
203
1361
L12
ICPC
Hand/finger symptom/complaint
2.2
9.1
85
424
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
9.1
98
517
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
9.1
98
517
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.6
9.1
55
226
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.2
9.1
36
117
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.9
9.1
44
161
C10AA01
ATC
simvastatin; oral
1.8
9.1
213
1452
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
15.9
9.1
14
9
NDL54
NOMESCO Finland
Tenolysis of hand
37.4
9.0
11
*
A01AB09
ATC
miconazole; local oral
2.6
9.0
54
221
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.1
8.9
37
124
SPAT1263
SPAT
Sampling
1.8
8.9
216
1485
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
8.9
174
1123
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
11.0
8.8
16
15
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
9.7
8.8
17
18
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
8.8
74
354
SPAT1229
SPAT
Assessment of need for aid
2.9
8.8
42
153
N05CF01
ATC
zopiclone; oral
1.8
8.7
172
1111
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.9
8.6
19
40
J45.1
ICD-10 Finland
Nonallergic asthma
2.8
8.6
43
160
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
8.6
38
132
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
8.6
44
166
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.9
8.6
25
66
R01AD09
ATC
mometasone; nasal
1.7
8.6
244
1748
Z50.1
ICD-10 Finland
Other physical therapy
3.2
8.6
34
111
N02AC04
ATC
dextropropoxyphene; oral
4.0
8.5
24
62
H02BX01
ATC
methylprednisolone, combinations; systemic
3.5
8.5
29
86
L28
ICPC
Limited function/disability (L)
2.1
8.5
85
437
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
91.4
8.4
9
*
NC1BG
NOMESCO Finland
Elbow MRI examination with high intensity magnet
91.4
8.4
9
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.4
90
474
NFM20
NOMESCO Finland
Excision of bursa of hip or thigh
+∞
8.4
8
*
NCL22
NOMESCO Finland
Myotomy or tenotomy of elbow or forearm
+∞
8.4
8
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.1
8.4
35
118
WX320
NOMESCO Finland
Spinalanesthesy
1.9
8.2
127
759
R52.9
ICD-10 Finland
Pain, unspecified
2.5
8.2
53
225
K02.1
ICD-10 Finland
Caries of dentine
1.7
8.2
304
2331
J01CA04
ATC
amoxicillin; systemic
1.9
8.2
431
3647
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.9
8.2
24
64
M75.8
ICD-10 Finland
Other shoulder lesions
4.1
8.1
22
55
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
8.3
8.1
17
21
SPAT1216
SPAT
Assessment of functional ability
2.1
8.1
78
394
WZC30
NOMESCO Finland
Teaching
2.1
8.1
89
473
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
9.1
8.1
16
18
B01AB05
ATC
enoxaparin; parenteral
1.8
8.1
166
1082
M24.2
ICD-10 Finland
Disorder of ligament
10.2
8.1
15
15
A10AE06
ATC
insulin degludec; parenteral
3.6
8.1
26
74
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.2
8.0
68
326
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
8.0
200
1376
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.9
8.0
38
138
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.0
8.0
98
542
P01AB01
ATC
metronidazole; oral, rectal
1.7
8.0
218
1538
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
4.1
8.0
22
56
M01AE01
ATC
ibuprofen; systemic, rectal
2.3
7.9
488
4325
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.7
7.9
18
39
A10AB04
ATC
insulin lispro; parenteral
3.9
7.9
23
61
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.8
242
1762
J01FA09
ATC
clarithromycin; systemic
1.7
7.8
168
1108
A10AC01
ATC
insulin (human); parenteral
2.6
7.8
46
187
R03DC03
ATC
montelukast; oral
2.0
7.8
90
487
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.0
7.8
22
57
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
4.4
7.7
19
44
M77.4
ICD-10 Finland
Metatarsalgia
3.2
7.7
31
102
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
7.7
93
511
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
7.7
68
332
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.3
7.7
61
285
C07AB02
ATC
metoprolol; systemic
1.9
7.6
102
580
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
7.6
83
439
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
3.1
7.6
32
108
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.7
7.6
42
165
A10AA02, ,
ATC
3.8
7.5
23
63
A46
ICD-10 Finland
Erysipelas
2.1
7.5
76
391
M19.8
ICD-10 Finland
Other specified arthrosis
3.5
7.5
26
78
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.1
7.5
31
104
A02BA02
ATC
ranitidine; systemic
1.9
7.5
101
577
C07AB07
ATC
bisoprolol; oral
1.7
7.5
245
1805
L17
ICPC
Foot/toe symptom/complaint
1.8
7.4
139
879
NBG10
NOMESCO Finland
Acromioplastia
13.6
7.4
12
9
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
13.6
7.4
12
9
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
7.4
38
144
N02BF01
ATC
gabapentin; oral
2.8
7.4
38
144
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
7.4
48
205
A10AE04
ATC
insulin glargine; parenteral
2.3
7.4
55
250
M20.2
ICD-10 Finland
Hallux rigidus
3.6
7.3
24
69
L16
ICPC
Ankle symptom/complaint
2.3
7.3
58
270
SFA10
NOMESCO Finland
One-surface restoration
1.6
7.3
284
2178
NCL50
NOMESCO Finland
Tenolysis or tenosynovectomy of elbow or forearm
+∞
7.3
7
*
M76.0
ICD-10 Finland
Gluteal tendinitis
6.4
7.3
18
29
M54.2
ICD-10 Finland
Cervicalgia
2.6
7.3
41
163
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.4
7.3
18
42
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.9
7.2
33
117
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
7.2
45
188
R5599
NOMESCO Finland
Other rehabilitation service
4.6
7.2
17
38
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.4
7.2
51
226
R05
ICD-10 Finland
Cough
1.8
7.2
112
669
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
7.2
143
920
H3603, E103,
ICD-10 Finland
20.3
7.2
10
5
S62.6
ICD-10 Finland
Fracture of other finger
3.1
7.1
29
96
SGA01
NOMESCO Finland
Emergency treatment
2.0
7.1
89
494
M01AC01
ATC
piroxicam; systemic, rectal
2.1
7.1
69
349
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
5.8
7.1
19
34
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
12.2
7.1
12
10
M70.5
ICD-10 Finland
Other bursitis of knee
12.2
7.1
12
10
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
7.1
130
817
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
7.0
40
160
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
7.0
102
596
L10
ICPC
Elbow symptom/complaint
3.0
7.0
30
103
WX290
NOMESCO Finland
Other blockage of nerve
1.6
7.0
236
1744
D06
ICPC
Abdominal pain localized other
2.4
6.9
46
198
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
6.9
22
62
C10AA05
ATC
atorvastatin; oral
1.6
6.9
214
1545
M47.82
ICD-10 Finland
Other spondylosis, cervical region
3.5
6.9
23
67
J01FA10
ATC
azithromycin; systemic
1.6
6.9
295
2304
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
6.9
307
2423
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.2
6.9
18
44
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.7
6.8
37
144
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
6.8
138
890
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
11.1
6.8
12
11
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
9.5
6.8
13
14
ZXD20
NOMESCO Finland
Day surgery
2.1
6.8
67
341
UJD02
NOMESCO Finland
Gastroscopy
2.9
6.8
31
110
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.8
127
801
G43.9
ICD-10 Finland
Migraine, unspecified
2.7
6.8
35
133
F51.0
ICD-10 Finland
Nonorganic insomnia
1.9
6.8
86
480
R20.2
ICD-10 Finland
Paraesthesia of skin
2.7
6.8
36
139
P01
ICPC
Feeling anxious/nervous/tense
2.2
6.8
56
266
J02AC01
ATC
fluconazole; systemic
1.6
6.8
215
1561
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
7.3
6.7
15
21
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
6.7
68
350
R02
ICPC
Shortness of breath/dyspnoea
2.1
6.7
65
329
WX704
NOMESCO Finland
Intubation
2.4
6.7
45
195
M71.0
ICD-10 Finland
Abscess of bursa
22.8
6.7
9
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.1
6.7
69
358
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.1
6.7
61
302
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
6.6
58
282
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
12.4
6.6
11
9
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
6.6
27
90
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
6.6
56
269
C09CA01
ATC
losartan; oral
1.7
6.6
136
882
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
6.6
146
966
C02AC05
ATC
moxonidine; oral
3.2
6.6
26
85
L02
ICPC
Back symptom/complaint
2.3
6.5
52
243
N05BA01
ATC
diazepam; systemic, rectal
2.0
6.5
72
383
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.6
6.5
21
60
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
3.3
6.5
24
75
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.3
6.5
24
75
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
6.5
45
198
Z01.2
ICD-10 Finland
Dental examination
1.6
6.5
223
1647
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.5
6.5
41
173
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
7.5
6.4
14
19
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
6.4
30
108
WZC00, ,
SPAT
2.2
6.4
55
265
K04.1
ICD-10 Finland
Necrosis of pulp
2.1
6.4
61
307
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.7
6.4
121
765
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.7
6.4
15
23
S01
ICPC
Pain/tenderness of skin
3.3
6.4
24
76
E0000UV, ,
ATC
1.6
6.4
207
1506
KMAK, ,
NOMESCO Finland
1.6
6.4
266
2053
M76.6
ICD-10 Finland
Achilles tendinitis
3.3
6.3
23
71
S63.6
ICD-10 Finland
Sprain and strain of finger(s)
3.5
6.3
21
61
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.1
6.3
16
27
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
6.3
119
750
Z00.0
ICD-10 Finland
General medical examination
1.9
6.3
94
552
M02AA15
ATC
diclofenac; topical
2.5
6.3
41
175
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
3.9
6.3
18
47
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
6.3
109
671
R4110
NOMESCO Finland
Physiotherapy
1.7
6.3
141
934
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
+∞
6.3
6
*
J01DA06
ATC
[U] cefuroxime
1.9
6.3
79
440
C08CA01
ATC
amlodipine; oral
1.6
6.2
191
1369
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.4
6.2
42
183
M77.0
ICD-10 Finland
Medial epicondylitis
5.9
6.2
16
28
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.5
6.2
38
158
C10AA04
ATC
fluvastatin; oral
2.4
6.2
44
196
A10AE05
ATC
insulin detemir; parenteral
2.7
6.2
33
128
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
6.2
34
134
JAH01
NOMESCO Finland
Laparoscopy
2.9
6.2
29
105
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
6.1
18
48
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
6.1
96
573
M62.6
ICD-10 Finland
Muscle strain
4.2
6.1
16
39
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
4.2
6.1
16
39
G54.0
ICD-10 Finland
Brachial plexus disorders
4.2
6.1
16
39
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
6.1
36
147
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
6.1
130
849
SPAT1211
SPAT
Application of soft bandage
2.3
6.1
45
204
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.5
6.1
20
58
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
5.3
6.1
17
33
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.9
6.0
27
95
Z3231
NOMESCO Finland
Registered nurse
1.7
6.0
138
918

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
144
675
2.54
18.79
1.4
1.2
27.55
36.58
iu/ml
0.69
53
242
137
640
2.53
17.92
1.4
1.2
8.97
19.91
u/ml
1.16
61
233
417
3111
2.48
17.78
5.8
3.7
11.59
12.38
mm/h
0.59
399
2860
350
2430
2.24
17.63
5.5
4.1
6.83
6.66
mmol/l
0.70
334
2263
184
1014
2.23
16.30
2.7
2.5
323.46
8354.90
umol/l
5.09
167
885
188
1144
1.99
12.16
2.2
2.0
150.64
275.58
u/l
0.79
178
1069
277
1920
1.91
12.12
2.6
2.4
—
—
—
0
0
295
2101
1.89
11.74
7.3
5.6
1.95
1.90
e9/l
0.25
272
1864
414
3310
2.06
11.51
8.3
7.2
77.13
78.40
u/l
0.27
396
3111
107
539
2.23
11.36
1.8
1.8
—
—
—
0
0
283
2006
1.86
11.26
8.8
6.3
1.22
1.22
mmol/l
0.14
260
1697
229
1529
1.86
10.94
4.6
3.2
32.47
37.27
ng/l
0.20
160
1024
502
4377
2.99
10.90
18.3
12.0
19.42
23.62
mg/l
2.49
429
3351
286
2048
1.84
10.88
7.3
5.6
0.04
0.04
e9/l
0.80
255
1773
283
2026
1.83
10.72
5.4
3.4
0.00
0.00
estimate
0.50
47
380
285
2047
1.83
10.66
7.3
5.6
0.59
0.57
e9/l
0.41
254
1772
292
2118
1.82
10.52
7.3
5.9
0.19
0.19
e9/l
0.08
268
1859
370
2888
1.89
10.49
5.8
3.9
—
—
—
0
0
143
842
1.95
9.88
5.7
3.7
1.01
1.02
kg/l
2.84
25
121
284
2068
1.78
9.87
5.4
3.4
0.00
0.00
estimate
-0.00
41
350
351
2722
1.82
9.84
5.8
3.9
101.40
3029.44
e6/l
—
5
45
281
2043
1.78
9.79
7.1
4.7
0.00
0.00
estimate
-0.00
41
363
191
1241
1.83
9.70
3.7
2.8
—
—
—
0
0
321
2432
1.78
9.66
9.3
9.4
4.16
4.08
e9/l
0.26
294
2133
237
1647
1.78
9.58
2.0
1.9
101.94
94.85
pmol/l
1.36
134
834
254
1803
1.77
9.53
7.6
5.5
1.21
1.21
mmol/l
0.93
242
1636
234
1623
1.78
9.50
4.5
3.2
5.18
5.85
ph
0.75
11
151
261
1878
1.75
9.26
13.7
12.3
1.22
1.23
inr
0.05
70
560
86
429
2.19
9.26
2.2
1.5
—
—
—
0
0
145
879
1.89
9.08
4.6
3.4
—
—
—
0
0
196
1306
1.78
9.02
3.9
3.7
8.49
8.11
mg/mmol
0.05
139
813
65
297
2.35
8.60
5.1
3.3
—
—
—
0
0
140
853
1.86
8.58
1.7
1.5
0.96
1.21
mg/l
0.60
113
661
186
1239
1.76
8.47
3.4
3.1
690.70
264.59
mg/l
0.43
132
776
154
982
1.79
8.08
2.3
2.0
2.97
3.09
mg/l
0.23
139
825
259
1910
1.68
8.03
7.6
6.2
—
—
—
0
0
185
1259
1.71
7.66
2.9
2.3
60.08
64.84
u/l
0.23
179
1166
189
1297
1.70
7.57
3.4
3.1
7.72
7.57
mmol/l
0.14
170
1098
283
2157
1.65
7.57
6.0
6.2
10.05
11.50
umol/l
2.12
276
2050
82
436
2.04
7.43
9.1
7.0
0.79
1.23
mmol/l
0.63
71
353
48
206
2.46
7.29
1.2
1.2
—
—
—
0
0
52
232
2.37
7.25
4.0
4.2
—
—
—
0
0
117
707
1.84
7.25
1.5
1.7
1109.55
1188.90
nmol/l
0.50
101
512
93
524
1.94
7.14
1.3
1.3
630.00
519.61
titre
0.25
16
102
250
1867
1.63
7.10
7.4
5.7
0.72
0.70
%
0.21
234
1728
158
1051
1.71
7.01
6.2
7.1
—
—
—
0
0
402
3393
1.72
6.92
4.5
3.9
14.76
14.72
pmol/l
0.10
375
3075
263
1999
1.61
6.89
7.6
5.7
27.61
27.92
%
0.17
250
1871
105
627
1.84
6.72
2.5
2.3
13.61
13.22
umol/l
0.20
98
591
254
1928
1.60
6.60
7.4
5.7
2.84
2.80
%
0.10
239
1797
258
1967
1.59
6.57
7.3
5.5
57.79
57.33
%
0.26
246
1838
55
263
2.21
6.54
2.3
2.7
7.40
7.95
e9/l
0.05
47
214
464
4106
1.90
6.51
5.6
4.5
1.82
1.91
mu/l
0.97
442
3730
232
1730
1.60
6.46
2.6
2.2
76.02
77.30
nmol/l
0.31
220
1559
150
1005
1.68
6.41
3.8
4.0
—
—
—
0
0
186
1318
1.63
6.38
2.3
2.1
—
—
—
0
0
158
1078
1.66
6.28
3.5
3.0
1609.41
1263.68
ng/l
0.44
142
912
127
818
1.72
6.26
2.5
2.3
4.82
6.49
e6/l
0.78
121
736
67
352
2.03
6.26
1.8
2.1
395.93
374.57
nmol/l
0.24
58
323
91
534
1.85
6.14
2.3
2.4
22.91
22.86
%
0.01
78
466
190
1367
1.60
6.06
3.5
3.1
30.31
30.99
u/l
0.11
182
1312
252
1942
1.56
5.93
7.7
5.9
8.61
8.62
%
0.02
238
1809
235
1785
1.56
5.89
4.5
4.4
35.62
35.79
g/l
0.20
225
1668
502
4605
2.22
5.77
20.4
13.7
139.65
139.74
mmol/l
0.34
496
4464
48
230
2.19
5.69
12.7
8.5
94.64
93.73
%
0.80
48
230
95
579
1.78
5.64
2.3
2.3
2.41
2.35
g/l
0.60
89
538
132
885
1.65
5.53
1.4
1.2
1.51
1.73
u/ml
0.08
45
229
192
1410
1.56
5.50
3.9
3.3
144.90
87.98
e6/l
0.28
158
992
502
4623
2.16
5.41
20.5
13.8
3.97
3.96
mmol/l
0.36
496
4471
239
1853
1.52
5.29
2.9
2.6
114.61
120.07
ug/l
0.17
227
1697
113
736
1.68
5.28
3.8
3.6
145.74
427.42
ng/l
1.56
86
572
28
112
2.58
4.96
1.2
1.1
—
—
—
0
0
168
1232
1.53
4.72
5.1
3.4
—
—
—
0
0
428
3807
1.59
4.61
22.8
15.9
331.94
332.27
g/l
0.34
428
3775
77
468
1.75
4.60
2.2
2.3
109.15
133.04
ug/g
0.56
60
372
152
1096
1.54
4.60
3.3
2.8
0.32
0.45
e6/l
0.53
132
829
34
156
2.26
4.50
2.5
1.9
—
—
—
0
0
63
363
1.83
4.49
2.9
3.6
2.17
2.04
mmol/l
0.08
55
292
461
4187
1.68
4.43
7.0
5.3
41.74
39.38
mmol/mol
4.88
440
3872
29
125
2.39
4.42
15.9
8.0
—
—
—
0
0
44
226
2.03
4.40
5.1
3.5
7.41
7.41
ph
—
6
33
42
212
2.06
4.40
4.1
3.8
—
—
—
0
0
58
328
1.86
4.39
10.4
7.9
—
—
—
0
0
364
3142
1.48
4.38
4.0
3.4
—
—
—
0
0
115
788
1.58
4.33
1.4
1.5
2.31
2.37
g/l
0.14
69
485
161
1192
1.50
4.26
3.4
2.9
28.13
104.45
e6/l
0.77
141
913
30
135
2.29
4.17
4.5
3.7
—
—
—
0
0
186
1424
1.47
4.15
2.7
3.4
2.35
2.36
mmol/l
0.27
171
1265
87
564
1.65
4.10
1.2
1.2
—
—
—
0
0
20
75
2.73
4.03
2.5
2.8
—
—
—
0
0
142
1038
1.50
3.96
6.3
3.7
0.00
0.00
estimate
-0.00
39
349
130
936
1.51
3.90
1.4
1.5
27.40
21.42
nmol/l
0.46
118
794
15
50
3.06
3.71
1.3
1.0
2.29
1.99
u/ml
—
6
17
143
1063
1.47
3.64
3.2
2.7
—
—
—
0
0
53
310
1.79
3.62
1.6
2.8
71.44
70.12
e9/l
0.11
46
234
50
288
1.81
3.59
1.5
1.4
—
—
—
0
0
41
223
1.91
3.52
1.2
1.3
—
26.69
—
0
19
217
1750
1.40
3.51
2.1
2.1
—
—
—
0
0
14
47
3.03
3.43
1.3
1.0
2.36
6.75
u/ml
—
6
11
67
426
1.65
3.41
2.7
2.5
1.72
1.77
%
0.25
61
379
62
387
1.68
3.38
4.9
3.9
—
—
—
0
0
110
793
1.49
3.24
3.2
2.7
517.48
546.96
mosm/kgh2o
0.79
98
685
13
39
3.39
3.24
1.2
1.3
—
—
—
0
0
44
252
1.81
3.24
5.1
2.6
—
—
—
0
0
523
5009
2.26
3.19
27.0
18.1
39.68
40.16
%
0.86
502
4660
234
1935
1.37
3.17
10.0
8.6
0.00
0.00
e9/l
0.50
196
1597
13
44
3.00
3.15
1.4
1.3
—
—
nmol/l
—
0
0
506
4795
1.83
3.15
13.2
9.5
25.15
25.81
u/l
0.45
498
4610
523
5014
2.23
3.09
26.6
18.0
255.92
254.23
e9/l
0.25
518
4864
523
5015
2.22
3.07
26.6
18.1
6.86
6.54
e9/l
3.24
518
4853
17
68
2.55
3.07
1.2
1.1
0.64
3.93
u/ml
—
7
30
523
5016
2.22
3.05
26.6
18.0
4.48
4.49
e12/l
0.13
517
4857
495
4669
1.69
3.04
16.9
11.4
—
—
—
0
0
89
623
1.51
3.02
2.7
2.6
3.09
3.10
e6/l
0.00
53
341
21
94
2.28
3.00
3.1
2.3
—
—
—
0
0
15
58
2.63
2.89
1.3
1.0
0.31
2.35
u/ml
—
6
24
330
2908
1.34
2.83
3.4
2.9
46.62
49.05
u/l
0.24
311
2721
12
39
3.12
2.78
1.3
1.3
—
—
—
0
0
14
54
2.63
2.72
1.2
1.8
—
—
—
0
0
65
437
1.55
2.66
2.2
2.5
5.05
8.87
umol/l
2.53
58
378
16
67
2.43
2.65
1.1
1.0
4.43
5.17
u/ml
—
6
26
28
494
0.54
2.60
1.6
1.4
—
—
—
0
0
104
774
1.43
2.58
2.1
3.0
2.43
2.45
mmol/l
1.21
93
689
422
3897
1.37
2.44
19.0
14.8
15.34
14.81
%
0.90
417
3811
15
64
2.38
2.40
1.1
1.0
0.22
1.14
u/ml
—
5
22
23
118
1.99
2.39
1.1
1.1
—
—
—
0
0
34
199
1.76
2.38
14.8
9.7
—
—
—
0
0
17
79
2.19
2.27
1.2
1.8
844.22
13766.61
e6/l
—
9
61
116
901
1.37
2.24
1.6
1.7
421.10
5298441.24
pmol/l
0.50
105
755
48
314
1.58
2.23
3.8
3.7
83.16
85.20
ng/l
0.07
43
282
149
1205
1.33
2.20
4.3
3.9
7.39
7.40
ph
0.44
23
227
29
166
1.79
2.20
5.3
3.2
—
—
—
0
0
28
160
1.79
2.14
1.4
1.9
1.60
1.63
g/l
0.06
23
138
87
652
1.40
2.08
1.7
1.8
—
—
—
0
0
5
10
5.03
2.07
1.0
2.4
0.97
1.27
ug/l
—
5
10
9
32
2.84
2.01
1.7
1.2
76.67
82.44
umol/l
—
9
32
25
141
1.81
2.00
1.0
1.0
—
—
—
0
0
8
27
2.99
1.94
1.0
1.1
—
—
—
0
0
6
16
3.78
1.94
3.0
2.9
36616.67
35587.81
ug/l
—
6
16
65
469
1.44
1.93
1.3
1.3
—
—
—
0
0
463
4388
1.38
1.89
5.3
4.3
6.19
5.88
mmol/l
3.60
441
4003
51
354
1.49
1.84
4.0
4.1
0.37
1.15
%
2.65
16
120
7
23
3.07
1.80
1.6
1.4
6.16
6.74
mmol/l
—
7
23
7
24
2.94
1.72
3.6
3.2
9.57
20.86
mu/l
—
7
24
21
118
1.81
1.72
1.8
1.4
242.33
307.87
ug/g
0.62
12
65
65
481
1.40
1.69
1.4
1.3
—
—
—
0
0
11
49
2.27
1.64
1.4
1.2
—
—
—
0
0
43
296
1.49
1.64
2.6
3.1
108.27
187.42
ng/l
1.88
37
265
18
98
1.87
1.63
1.7
2.2
3897.37
2587.95
u/l
—
6
42
154
1805
0.79
1.63
3.3
2.8
—
—
—
0
0
47
331
1.46
1.60
4.2
4.2
0.00
0.10
%
2.39
13
97
141
1178
1.27
1.59
5.5
3.0
—
—
—
0
0
9
37
2.46
1.48
1.0
3.1
—
—
—
0
0
45
321
1.44
1.45
1.5
1.6
—
—
—
0
0
44
314
1.44
1.42
4.3
4.2
0.00
0.11
%
0.82
13
81
21
126
1.69
1.42
1.1
1.4
134.17
243.85
miu/ml
—
6
56
15
81
1.88
1.41
1.4
1.2
415.40
486.89
mg/l
0.45
15
74
10
46
2.20
1.40
1.1
1.7
—
—
—
0
0
28
182
1.57
1.40
2.2
4.1
24.37
24.03
mmol/l
0.15
28
176
9
41
2.21
1.37
1.0
1.1
—
—
—
0
0
48
353
1.39
1.33
2.3
2.0
66.58
42.45
u/l
0.29
38
302
23
145
1.61
1.31
1.4
1.6
—
—
—
0
0
8
34
2.37
1.29
1.1
2.9
2.21
6.35
umol/l
—
8
23
9
44
2.06
1.27
5.6
4.2
—
—
—
0
0
44
322
1.40
1.26
3.8
3.9
0.50
0.70
%
0.32
14
97
21
131
1.63
1.25
5.9
3.5
0.23
0.24
g/l
0.03
11
54
142
1221
1.22
1.23
1.4
1.4
—
—
—
0
0
11
57
1.95
1.17
1.0
1.1
—
—
—
0
0
18
110
1.66
1.17
1.7
3.1
—
—
—
0
0
69
549
1.29
1.16
1.6
1.6
—
—
—
0
0
0
33
0.00
1.16
0.0
13.3
—
834.67
—
0
33
0
34
0.00
1.16
0.0
19.1
—
1599.47
—
0
34
15
87
1.74
1.16
3.8
3.0
8.53
8.26
kpa
0.25
15
87
37
267
1.41
1.16
1.3
1.2
—
—
—
0
0
13
72
1.83
1.16
4.0
2.6
—
—
—
0
0
25
167
1.52
1.14
1.2
1.2
—
—
—
0
0
30
209
1.46
1.13
2.7
2.4
—
—
—
0
0
7
30
2.35
1.12
2.0
1.5
9.64
11.31
%
—
7
30
475
4591
1.28
1.10
5.7
4.7
2.74
2.83
mmol/l
1.62
457
4238
132
1140
1.21
1.09
4.8
4.6
2.11
2.37
ug/l
0.27
119
1023
42
314
1.37
1.08
1.1
1.1
—
—
—
0
0
11
59
1.88
1.08
2.4
1.4
—
—
—
0
0
450
4327
1.24
1.07
4.6
3.8
1.39
1.28
mmol/l
1.86
426
3969
59
466
1.30
1.06
2.7
4.5
2.79
40.56
ug/l
1.35
49
372
12
67
1.81
1.05
1.1
1.0
—
11.92
—
0
6
11
60
1.85
1.03
3.2
2.7
108.00
105.50
mmol/l
1.42
11
60
11
60
1.85
1.03
3.2
2.7
3.88
3.99
mmol/l
0.37
11
60
11
60
1.85
1.03
3.2
2.7
—
—
—
0
0
14
83
1.70
1.02
1.2
1.2
—
—
—
0
0
19
123
1.56
1.01
7.1
4.6
—
—
—
0
0
25
173
1.47
0.99
1.4
3.3
31.55
1584.54
u/ml
1.07
20
152
0
29
0.00
0.98
0.0
2.4
—
—
—
0
0
465
4500
1.23
0.95
5.2
4.3
4.71
4.77
mmol/l
0.56
447
4183
18
267
0.66
0.93
1.8
1.8
—
—
—
0
0
18
118
1.54
0.92
1.8
1.7
0.23
0.25
g/l
0.29
18
112
6
29
2.08
0.89
1.7
1.9
—
—
—
0
0
18
121
1.50
0.83
1.8
1.7
1.16
1.24
g/l
0.43
18
115
11
65
1.71
0.83
1.7
2.7
62.91
64.19
%
0.09
11
65
53
433
1.25
0.77
1.6
1.5
—
—
—
0
0
5
25
2.01
0.73
2.6
3.3
440.00
924.20
u/ml
—
5
25
9
56
1.62
0.72
1.0
1.0
1.30
1.42
g/l
—
9
49
57
474
1.23
0.71
1.6
1.6
—
—
—
0
0
9
57
1.59
0.71
1.1
1.2
—
—
—
0
0
12
77
1.57
0.69
1.2
2.8
—
—
—
0
0
14
95
1.49
0.64
1.1
3.9
—
—
—
0
0
34
270
1.28
0.64
5.4
2.8
21.96
45.63
u/ml
1.55
34
260
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
459
4474
1.17
0.64
5.1
4.3
1.47
1.51
mmol/l
0.93
436
4131
46
380
1.23
0.63
1.2
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
1655.86
—
0
21
8
52
1.55
0.59
1.0
1.1
—
—
—
0
0
15
106
1.43
0.58
1.8
2.0
4.26
6.51
iu/l
—
5
39
8
54
1.49
0.57
1.1
1.2
—
—
—
0
0
8
55
1.46
0.56
1.1
1.0
—
—
—
0
0
15
107
1.41
0.56
1.3
1.2
—
—
—
0
0
6
37
1.63
0.55
1.2
2.9
—
—
—
0
0
10
66
1.52
0.53
1.1
1.4
—
—
—
0
0
11
75
1.48
0.51
2.0
1.6
—
—
—
0
0
129
1183
1.12
0.50
1.8
1.6
1.39
1.37
mmol/l
0.11
114
987
12
84
1.44
0.49
2.3
2.9
—
—
—
0
0
7
46
1.53
0.48
1.0
1.2
—
—
—
0
0
7
47
1.50
0.47
2.1
1.7
1.27
1.52
mmol/l
—
7
47
7
50
1.41
0.45
1.3
2.5
—
—
—
0
0
24
296
0.80
0.45
1.6
1.4
—
—
—
0
0
24
295
0.80
0.43
1.5
1.4
—
—
—
0
0
15
196
0.76
0.43
1.1
1.1
—
—
—
0
0
5
31
1.62
0.43
1.0
1.2
1587.60
1704.55
e6/l
—
5
20
6
95
0.63
0.42
1.5
1.5
—
—
—
0
0
5
32
1.57
0.42
1.2
1.0
266.40
288.42
mg/l
—
5
26
5
33
1.52
0.41
1.0
1.0
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
108054.70
—
0
10
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
47
409
1.16
0.41
1.6
1.4
—
—
—
0
0
8
61
1.32
0.39
1.3
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
9
66
1.37
0.38
1.2
1.2
—
—
—
0
0
14
108
1.30
0.35
1.1
1.1
—
—
—
0
0
6
87
0.69
0.33
3.5
3.5
7.43
7.42
ph
—
6
73
10
74
1.36
0.32
1.3
1.2
—
—
—
0
0
10
74
1.36
0.32
1.5
1.6
—
—
—
0
0
7
53
1.32
0.31
1.3
3.0
—
—
—
0
0
31
270
1.16
0.29
1.3
2.3
—
—
—
0
0
9
74
1.22
0.25
1.7
1.4
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.10
—
0
7
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
14.63
—
0
9
6
50
1.20
0.19
1.2
1.2
—
—
—
0
0
7
60
1.17
0.18
1.0
1.9
—
—
—
0
0
5
67
0.74
0.17
1.0
1.2
—
—
—
0
0
8
70
1.14
0.16
5.9
3.6
—
—
—
0
0
6
77
0.78
0.15
1.3
1.1
—
—
—
0
0
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
45
1.11
0.10
1.6
1.2
—
—
—
0
0
5
47
1.06
0.09
1.0
2.8
—
1.67
—
0
21
5
48
1.04
0.09
2.0
2.4
—
—
—
0
0
11
124
0.88
0.09
1.5
1.3
—
—
—
0
0
33
348
0.94
0.08
6.2
3.5
—
—
—
0
0
32
303
1.06
0.08
1.2
1.2
227.75
156.43
iu/ml
0.40
13
127
7
67
1.05
0.08
6.0
3.0
2.72
4.11
e9/l
—
7
67
6
70
0.86
0.07
1.5
1.4
—
—
—
0
0
6
70
0.86
0.07
1.5
1.3
—
—
—
0
0
6
73
0.82
0.07
1.5
1.4
—
—
—
0
0
9
87
1.04
0.07
4.8
3.7
17.60
3250.27
u/ml
—
9
81
8
91
0.88
0.07
1.3
1.9
—
—
—
0
0
15
138
1.09
0.06
2.9
2.8
—
—
—
0
0
11
118
0.93
0.03
2.7
2.7
1.77
1.56
mg/l
0.29
11
106
68
671
1.02
0.02
3.5
2.9
0.68
0.74
ug/l
0.36
47
443
12
114
1.05
0.00
1.3
1.5
—
—
—
0
0
42
414
1.02
0.00
1.4
1.4
—
—
—
0
0
12
115
1.04
0.00
1.3
1.8
—
—
—
0
0
12
115
1.04
0.00
1.3
1.8
—
—
—
0
0
12
115
1.04
0.00
1.3
1.8
—
—
—
0
0
11
107
1.03
0.00
1.4
1.8
—
—
—
0
0
12
118
1.02
0.00
1.8
1.4
227.75
316.75
mu/l
1.01
12
108
58
582
1.00
0.00
1.4
1.3
—
—
—
0
0
7
71
0.99
0.00
6.4
3.2
49.14
57.51
%
—
7
71
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
2.6
2.7
—
—
—
0
0
5
53
0.94
0.00
1.2
2.2
32.00
32.89
pg
—
5
53
0
7
0.00
0.00
0.0
1.6
—
36.00
—
0
7
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
16.00
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
4949.20
—
0
5
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.5
—
0.22
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.14
—
0
5

Mortality – FinRegistry

Association

Association between endpoint M13_CHRONSYNOVITISHANDWRIST and mortality.

Females

Parameter HR [95% CI] p-value
M13_CHRONSYNOVITISHANDWRIST 1.108 [0.94, 1.3] 0.21
Birth year 0.995 [0.99, 1.0] 0.231

During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 1878 females with M13_CHRONSYNOVITISHANDWRIST died.

Males

Parameter HR [95% CI] p-value
M13_CHRONSYNOVITISHANDWRIST 1.158 [0.99, 1.36] 0.074
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 238 out of 1368 males with M13_CHRONSYNOVITISHANDWRIST died.

Mortality risk

Mortality risk for people of age

years, who have M13_CHRONSYNOVITISHANDWRIST.

N-year risk Females Males
1 0.098% 0.258%
5 0.652% 1.328%
10 1.581% 3.134%
15 2.973% 5.697%
20 5.195% 10.039%

Relationships between endpoints

Index endpoint: M13_CHRONSYNOVITISHANDWRIST – Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data