Listeriosis

AB1_LISTERIOSIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A32
  • Hospital discharge: ICD-9 027[0]
  • Hospital discharge: ICD-8 027[0]
  • Cause of death: ICD-10 A32
  • Cause of death: ICD-9 027[0]
  • Cause of death: ICD-8 027[0]

2 out of 7 registries used, show all original rules.

176

4. Check minimum number of events

None

176

5. Include endpoints

None

176

6. Filter based on genotype QC (FinnGen only)

169

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1333 676 639
Only index persons 984 554 430
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 69.92 69.30 70.68
Only index persons 70.94 69.41 72.91

-FinnGen-

Key figures

All Female Male
Number of individuals 169 85 84
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 69.69 65.73 73.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
176
Matched controls
1760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A32.7
ICD-10 Finland
Listerial sepsis
+∞
147.3
120
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
68.5
93.9
53
11
R50.9
ICD-10 Finland
Fever, unspecified
7.9
35.5
62
113
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
30.1
28
*
G01*A32.1
ICD-10 Finland
Listerial meningitis
+∞
25.6
24
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.9
24.2
28
30
A46
ICD-10 Finland
Erysipelas
7.7
18.9
29
44
L04AX01
ATC
azathioprine; systemic
18.2
18.2
28
18
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
17.6
56
167
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.5
15.1
27
48
B03XA02
ATC
darbepoetin alfa; parenteral
23.6
15.1
21
10
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
14.8
14
*
WX892
NOMESCO Finland
Monitored bed care
6.5
14.6
26
46
TK800
NOMESCO Finland
Hemodialysis
33.1
14.2
18
6
ZX120
NOMESCO Finland
Intravenous
4.7
13.8
37
95
A41.8
ICD-10 Finland
Other specified sepsis
+∞
13.7
13
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
12.7
56
205
A32.8
ICD-10 Finland
Other forms of listeriosis
+∞
12.6
12
*
A32.1
ICD-10 Finland
Listerial meningitis and meningoencephalitis
+∞
12.6
12
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
12.6
94
471
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.4
12.4
36
98
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6.0
12.2
23
43
N17.9
ICD-10 Finland
Acute renal failure, unspecified
11.8
12.2
22
21
L04AA06
ATC
mycophenolic acid; systemic
37.8
11.4
14
*
B01AA03
ATC
warfarin; systemic
3.2
11.2
62
259
C03CA01
ATC
furosemide; systemic
2.9
11.1
89
456
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
19.4
10.9
16
9
H02AB06
ATC
prednisolone; systemic
2.9
10.6
105
599
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
14.3
10.4
17
13
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
10.1
69
321
ZXD05
NOMESCO Finland
Urgent procedure
2.8
9.8
71
340
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
9.6
99
566
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
9.5
33
102
0270X
ICD-9 Finland
Other zoonotic bacterial diseases, Listeriosis[LISTERIOSIS ALIA (EI SYNNYNNÄINEN)]
+∞
9.5
9
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
9.5
9
*
M05BA04
ATC
alendronic acid; oral
3.7
9.2
33
104
J01MA02
ATC
ciprofloxacin; systemic
2.6
8.8
90
506
I50.9
ICD-10 Finland
Heart failure, unspecified
3.0
8.5
46
186
J01MA12
ATC
levofloxacin; systemic
2.9
8.5
48
199
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.3
8.5
23
59
N02AA05
ATC
oxycodone; systemic
2.9
8.4
50
214
R2110
NOMESCO Finland
Giving the first information
5.0
8.3
19
42
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
12.6
8.2
14
12
I50.0
ICD-10 Finland
Congestive heart failure
3.7
8.2
29
90
Z49.1
ICD-10 Finland
Extracorporeal dialysis
35.1
8.2
10
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
4.8
8.1
19
43
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.5
8.1
21
52
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.6
8.0
20
48
A11CC03
ATC
alfacalcidol; systemic
11.6
8.0
14
13
JN4BD
NOMESCO Finland
Extensive body CT
3.4
7.8
30
99
127
Kela drug reimbursment
Transplant complication
26.3
7.7
10
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
7.6
47
204
N18.0
ICD-10 Finland
End-stage renal disease
83.5
7.5
8
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.8
7.4
24
70
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
7.4
49
220
B01AB05
ATC
enoxaparin; parenteral
2.4
7.4
72
389
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
7.4
27
86
A32.9
ICD-10 Finland
Listeriosis, unspecified
+∞
7.3
7
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.5
7.3
15
19
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.5
7.2
18
43
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.6
7.0
25
78
L04AA01
ATC
[U] ciclosporin
17.5
6.8
10
6
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.1
6.8
32
119
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
6.8
49
229
UJF32
NOMESCO Finland
Coloscopy
2.4
6.6
59
304
SPAT1229
SPAT
Assessment of need for aid
3.5
6.6
24
76
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
7.9
6.6
14
19
L01BA01
ATC
methotrexate; systemic
7.0
6.5
15
23
XW000
NOMESCO Finland
Bone marrow biopsy
6.0
6.5
17
31
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
8.7
6.5
13
16
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
6.3
64
348
N17.8
ICD-10 Finland
Other acute renal failure
27.8
6.3
8
*
L04AD02
ATC
tacrolimus; systemic
+∞
6.3
6
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
6.3
6
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.2
6.1
17
44
C03DA01
ATC
spironolactone; oral
2.8
6.1
34
139
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
6.0
32
127

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
105
334
6.31
33.48
9.2
3.3
—
—
—
0
0
28
34
9.60
22.02
2.4
1.5
2.85
0.27
ug/l
1.82
28
24
45
103
5.53
19.60
9.3
3.0
1.16
0.77
%
0.52
32
35
41
87
5.84
19.38
9.7
3.0
0.97
0.21
%
1.85
29
24
115
555
4.09
18.28
14.3
5.3
0.54
0.68
%
1.97
109
513
117
575
4.09
18.02
14.7
5.2
1.99
2.86
%
5.19
111
533
117
577
4.07
17.88
15.4
5.7
8.87
8.78
%
0.09
111
538
118
591
4.02
17.50
15.1
5.4
—
—
—
0
0
40
91
5.39
17.42
8.5
3.3
3.19
0.33
%
0.44
26
24
41
97
5.21
17.06
9.5
3.1
0.00
0.14
%
0.99
28
29
116
591
3.82
16.39
15.1
5.5
23.89
27.83
%
2.12
110
552
42
109
4.75
15.57
4.9
2.5
88.73
67.82
e9/l
1.13
37
82
119
630
3.74
15.56
13.1
5.1
0.03
0.04
e9/l
2.02
102
544
53
165
4.17
15.52
3.9
1.7
—
—
—
0
0
114
589
3.66
15.45
13.2
5.2
61.55
56.78
%
2.72
108
550
118
627
3.68
15.21
13.1
5.1
0.92
0.59
e9/l
0.70
103
544
51
158
4.14
14.99
4.3
2.5
2.20
1.69
%
1.05
46
140
119
643
3.63
14.79
13.2
5.2
1.77
1.89
e9/l
0.29
104
570
119
655
3.52
14.10
13.7
5.5
0.18
0.18
e9/l
0.11
103
573
36
93
4.61
13.32
5.5
2.5
—
—
—
0
0
110
593
3.28
13.18
12.8
3.6
31.96
35.94
g/l
7.54
104
552
55
195
3.65
13.16
4.6
2.1
19.42
20.46
%
0.21
49
168
47
153
3.83
12.72
1.6
1.3
1374.55
606.67
titre
0.64
11
30
125
748
3.32
12.13
24.0
8.2
4.81
3.99
e9/l
1.69
114
652
42
134
3.80
11.63
1.7
1.8
—
—
—
0
0
74
353
2.89
10.42
3.2
2.0
4.09
3.29
mg/l
1.30
63
294
111
665
2.81
9.94
27.2
15.2
1.56
1.30
inr
1.45
36
171
23
55
4.66
9.23
3.6
2.6
—
—
—
0
0
18
27
7.30
7.82
10.5
7.4
—
—
—
0
0
91
540
2.42
7.64
5.1
2.6
187.12
121.85
ug/l
1.01
85
487
29
99
3.31
7.09
2.1
1.4
—
—
—
0
0
13
14
9.92
6.91
16.9
2.9
—
—
—
0
0
79
456
2.33
6.89
3.6
3.1
—
—
—
0
0
28
96
3.28
6.79
15.7
6.2
—
—
—
0
0
31
114
3.09
6.70
8.7
3.0
0.84
1.90
mmol/l
1.06
23
94
78
452
2.30
6.70
4.5
3.0
71.99
195.30
e6/l
0.38
65
338
59
303
2.42
6.67
3.6
2.4
5.22
4.98
e6/l
0.07
53
272
108
725
2.27
6.41
21.1
5.1
1.18
1.22
mmol/l
6.31
95
613
30
112
3.02
6.31
2.1
1.4
—
—
—
0
0
100
661
2.19
6.03
17.7
4.6
1.18
1.22
mmol/l
5.00
94
593
84
519
2.18
6.01
5.6
3.7
155.09
82.05
e6/l
0.30
67
363
38
167
2.63
5.90
2.0
1.4
—
—
—
0
0
10
9
11.69
5.87
1.3
1.3
—
—
—
0
0
70
406
2.20
5.83
4.5
2.9
0.26
0.39
e6/l
0.57
59
293
14
23
6.51
5.82
1.4
1.5
—
—
—
0
0
12
16
7.96
5.73
3.4
2.2
13.25
15.61
%
—
6
8
55
293
2.28
5.60
4.5
2.8
518.52
539.39
mosm/kgh2o
0.27
50
242
36
159
2.59
5.52
22.6
5.8
1.12
1.15
mmol/l
0.01
29
137
37
171
2.47
5.15
1.7
1.3
—
—
—
0
0
10
12
8.75
5.13
3.7
3.8
—
—
—
0
0
10
12
8.75
5.13
2.1
1.4
—
—
—
0
0
12
20
6.35
5.01
1.4
1.3
—
—
—
0
0
28
115
2.71
4.93
10.0
3.0
—
—
—
0
0
11
17
6.82
4.85
2.1
1.4
—
—
—
0
0
9
10
9.41
4.84
1.1
1.0
—
—
—
0
0
86
573
1.98
4.71
6.1
3.9
49.72
46.57
ng/l
0.09
72
429
21
76
3.00
4.64
1.5
1.3
—
—
—
0
0
64
387
2.03
4.59
4.5
2.8
—
—
—
0
0
10
15
7.00
4.53
2.8
2.5
—
—
—
0
0
11
20
5.79
4.36
2.7
2.2
7.41
8.00
kpa
0.56
11
20
10
16
6.55
4.36
3.2
1.7
—
—
—
0
0
34
165
2.31
4.22
14.4
5.5
104.71
103.91
mmol/l
0.43
34
165
9
13
7.23
4.22
2.7
1.3
1.97
1.58
mmol/l
—
9
13
13
31
4.44
4.11
3.7
1.8
2.07
1.64
mg/l
0.74
13
26
31
147
2.35
4.05
6.3
4.3
17.98
6.30
ug/l
0.53
26
129
12
27
4.69
4.02
5.8
1.4
—
—
—
0
0
68
438
1.90
3.96
6.0
2.0
—
—
—
0
0
17
60
3.03
3.92
1.6
1.3
—
—
—
0
0
10
20
5.23
3.75
1.9
1.9
—
—
—
0
0
10
20
5.23
3.75
4.8
2.0
—
—
—
0
0
85
596
1.82
3.74
21.1
8.7
0.00
0.01
e9/l
0.22
69
492
9
16
5.86
3.71
1.6
1.3
6.18
6.34
mmol/l
—
9
16
9
16
5.86
3.71
4.8
2.0
—
—
—
0
0
9
16
5.86
3.71
1.0
1.1
—
—
—
0
0
28
132
2.33
3.70
5.9
2.0
497.71
102.62
ug/g
1.36
21
105
84
591
1.81
3.62
2.4
2.0
95.08
95.09
pmol/l
0.00
50
311
20
81
2.66
3.61
15.1
6.7
92.64
93.96
%
0.30
20
81
7
9
8.04
3.59
2.3
1.0
—
—
—
0
0
22
94
2.53
3.58
24.7
3.8
—
—
—
0
0
30
148
2.24
3.57
2.4
1.5
—
—
—
0
0
9
17
5.52
3.56
2.3
2.8
56.33
57.06
%
—
9
17
41
231
2.01
3.48
4.1
2.9
3.32
2.48
e6/l
0.21
29
119
120
950
1.83
3.39
7.5
4.3
—
—
—
0
0
48
291
1.89
3.28
2.4
1.7
1066.95
1142.35
nmol/l
0.25
40
214
7
11
6.57
3.21
2.0
1.0
283.86
283.00
mosm/kgh2o
—
7
6
52
328
1.83
3.13
15.0
6.1
—
—
—
0
0
67
457
1.75
3.10
8.0
3.3
7.41
7.40
ph
0.59
11
82
64
431
1.76
3.10
2.8
2.0
605.61
196.71
u/l
0.41
59
407
8
16
5.18
3.09
1.6
1.1
—
—
—
0
0
24
115
2.26
3.06
1.6
1.4
—
—
—
0
0
42
251
1.88
2.98
2.0
1.4
2.20
2.75
g/l
1.04
37
138
76
544
1.70
2.93
5.7
4.0
—
6.03
—
0
34
78
566
1.68
2.83
2.6
2.1
—
—
—
0
0
9
23
4.07
2.81
2.4
1.5
—
—
—
0
0
9
23
4.07
2.81
3.2
2.1
113.11
127.36
g/l
—
9
14
18
81
2.36
2.64
1.2
1.3
—
31.75
—
0
6
89
682
1.62
2.53
6.6
4.1
0.00
0.00
estimate
-0.00
22
134
7
16
4.51
2.50
1.0
1.3
—
—
—
0
0
6
12
5.13
2.42
2.5
1.3
3.53
2.76
u/ml
—
6
12
6
12
5.13
2.42
3.8
1.9
—
—
—
0
0
6
12
5.13
2.42
3.5
1.0
86.47
91.03
%
—
6
12
30
176
1.85
2.24
1.3
1.3
—
—
—
0
0
60
428
1.61
2.23
4.0
2.9
7.00
7.13
mmol/l
0.10
54
347
8
24
3.44
2.21
2.4
1.4
22734.50
18427.07
e6/l
—
8
14
7
19
3.79
2.17
2.0
12.3
10.01
6.81
mmol/l
—
7
13
6
14
4.40
2.17
1.2
1.1
—
—
—
0
0
61
440
1.59
2.16
4.5
3.7
18.20
5.85
mg/mmol
1.47
44
265
5
10
5.11
2.08
1.0
1.4
—
—
—
0
0
5
10
5.11
2.08
1.0
1.2
—
—
—
0
0
11
45
2.54
1.97
5.6
4.1
—
—
—
0
0
86
683
1.51
1.93
8.3
5.5
0.00
0.00
estimate
-0.00
21
119
57
415
1.55
1.91
5.5
3.0
3094.11
34.03
mg/l
1.38
44
259
22
123
1.90
1.90
6.8
3.6
—
—
—
0
0
86
687
1.49
1.85
6.8
4.2
0.00
0.00
estimate
-0.00
20
117
5
12
4.25
1.83
1.6
1.3
—
—
—
0
0
5
13
3.92
1.72
1.2
1.2
—
—
—
0
0
14
69
2.12
1.70
46.9
7.8
—
—
—
0
0
7
25
2.87
1.67
3.0
1.4
1532.71
334.36
mu/l
—
7
25
48
348
1.52
1.62
5.5
2.7
344.24
6815.66
umol/l
1.74
41
291
16
85
1.97
1.61
5.2
3.5
13.48
7.65
e9/l
—
9
64
8
33
2.49
1.56
1.1
1.2
—
—
—
0
0
13
65
2.08
1.53
5.7
2.0
1.62
1.14
%
0.52
13
65
47
344
1.50
1.51
1.3
1.3
—
—
—
0
0
51
380
1.48
1.50
8.5
4.4
0.00
0.00
estimate
-0.00
21
120
5
16
3.18
1.45
2.2
1.2
—
—
—
0
0
58
447
1.44
1.43
5.3
4.1
—
—
—
0
0
6
24
2.55
1.31
1.2
1.2
—
—
—
0
0
22
141
1.64
1.24
13.4
3.3
—
—
—
0
0
12
64
1.94
1.21
5.2
2.0
0.67
0.66
%
0.03
12
64
116
1027
1.38
1.20
8.7
4.0
23.45
11.83
mm/h
6.38
110
927
8
40
2.05
1.13
5.1
2.5
—
—
—
0
0
43
328
1.41
1.11
6.4
4.1
—
—
—
0
0
9
45
2.05
1.06
1.6
1.2
—
—
—
0
0
109
966
1.34
1.06
5.0
4.1
—
—
—
0
0
27
193
1.47
0.98
1.2
1.3
—
—
—
0
0
30
220
1.44
0.96
1.1
1.3
111.33
33.63
iu/ml
—
6
73
111
996
1.31
0.94
4.7
3.8
15.09
14.92
pmol/l
0.25
105
868
14
87
1.66
0.90
1.1
1.2
—
—
—
0
0
27
203
1.39
0.76
1.2
1.3
7.11
8.94
u/ml
—
9
74
5
25
2.03
0.73
2.8
2.0
—
—
—
0
0
5
25
2.03
0.73
2.8
2.0
104.60
106.40
mmol/l
—
5
25
5
25
2.03
0.73
2.8
2.0
3.96
4.05
mmol/l
—
5
25
5
26
1.95
0.71
11.2
2.5
20.80
16.96
u/ml
—
5
26
21
280
0.72
0.70
2.9
3.3
0.72
0.79
ug/l
0.16
16
194
124
1321
0.79
0.67
4.9
4.7
1.40
1.48
mmol/l
1.18
114
1193
7
44
1.61
0.66
2.0
1.6
—
—
—
0
0
5
29
1.74
0.64
5.8
1.9
—
—
—
0
0
8
54
1.50
0.58
2.9
2.0
—
—
—
0
0
15
107
1.44
0.57
5.6
3.8
—
—
—
0
0
126
1331
0.81
0.56
5.1
4.7
4.16
4.55
mmol/l
4.54
118
1210
36
429
0.80
0.54
3.6
3.1
—
—
—
0
0
6
100
0.59
0.53
1.7
1.2
—
—
—
0
0
7
106
0.65
0.50
1.9
1.3
—
—
—
0
0
11
78
1.44
0.44
6.4
3.9
—
—
—
0
0
121
1270
0.85
0.42
5.0
4.2
1.32
1.26
mmol/l
0.48
113
1139
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
5
35
1.44
0.39
1.2
1.1
—
—
—
0
0
5
36
1.40
0.38
1.0
1.3
—
—
—
0
0
131
1362
0.85
0.37
5.5
5.4
2.36
2.65
mmol/l
3.31
121
1228
44
492
0.86
0.34
5.2
5.6
2.53
3.20
ug/l
0.32
39
425
36
316
1.18
0.33
7.9
4.8
1.01
1.02
kg/l
—
6
44
140
1353
1.17
0.32
53.3
12.7
28.97
23.00
mg/l
1.53
132
1044
8
65
1.24
0.27
2.1
1.3
—
—
—
0
0
14
116
1.22
0.23
1.9
1.4
—
—
—
0
0
41
375
1.12
0.22
6.9
3.6
—
—
—
0
0
129
1326
0.90
0.21
5.1
5.1
6.41
6.05
mmol/l
1.04
118
1188
0
11
0.00
0.21
0.0
1.1
—
233.55
—
0
11
0
10
0.00
0.21
0.0
1.0
—
280.80
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
144
1471
0.88
0.21
69.9
20.1
37.19
39.74
%
5.19
136
1386
6
48
1.26
0.20
10.2
5.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
2.57
—
0
14
7
61
1.15
0.18
4.9
2.5
—
—
—
0
0
5
70
0.71
0.17
1.8
1.4
—
—
—
0
0
6
79
0.75
0.16
1.3
1.2
—
—
—
0
0
9
110
0.81
0.13
1.6
1.5
—
—
—
0
0
127
1244
1.08
0.13
5.4
4.7
2.09
1.99
mu/l
0.34
117
1089
11
97
1.14
0.09
5.0
3.2
—
—
—
0
0
6
56
1.07
0.09
1.0
1.6
—
—
—
0
0
37
380
0.97
0.03
1.8
1.6
1.43
1.27
mmol/l
0.59
31
319
140
1391
1.03
0.02
43.2
12.5
—
—
—
0
0
28
286
0.98
0.00
1.4
1.2
0.94
1.06
u/ml
—
10
75
127
1276
0.98
0.00
7.7
6.3
42.32
40.45
mmol/mol
0.89
116
1164
9
89
1.01
0.00
2.6
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
243.71
—
0
7
0
5
0.00
-0.00
0.0
9.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
1.54
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
136.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.34
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
14.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
72
0.97
-0.00
5.4
3.0
3.77
4.29
pmol/l
—
7
61
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.3
—
0.70
—
0
6
0
6
0.00
-0.00
0.0
10.8
—
537.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
25.2
—
989.83
—
0
6

Mortality – FinRegistry

Association

Association between endpoint AB1_LISTERIOSIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_LISTERIOSIS 4.859 [2.89, 8.17] < 0.001
Birth year 0.999 [0.99, 1.01] 0.824

During the follow-up period (1.1.1998 — 31.12.2019), 205 out of 348 females with AB1_LISTERIOSIS died.

Males

Parameter HR [95% CI] p-value
AB1_LISTERIOSIS 4.353 [2.43, 7.78] < 0.001
Birth year 0.985 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 223 out of 356 males with AB1_LISTERIOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_LISTERIOSIS.

N-year risk Females Males
1 0.565% 0.673%
5 3.177% 4.698%
10 7.736% 11.197%
15 14.768% 20.144%
20 25.68% 32.273%

Relationships between endpoints

Index endpoint: AB1_LISTERIOSIS – Listeriosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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