Traumatic amputation of ankle and foot

ST19_TRAUMAT_AMPUT_ANKLE_FOOT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S98 Cause of death: ICD-10 — S98 2 out of 7 registries used, show all original rules.	92
4. Check minimum number of events None	92
5. Include endpoints None	92
6. Filter based on genotype QC (FinnGen only)	89

Control definitions (FinnGen only)

Control exclude: ST19_INJURI_ANKLE_FOOT

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S90
Name in latin: Amputatio traumatica tarsi/pedis

NAME	ST19_TRAUMAT_AMPUT_ANKLE_FOOT
CONTROL_EXCLUDE	ST19_INJURI_ANKLE_FOOT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S98
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S98
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic amputation of ankle and foot based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	89	21	68
Unadjusted period prevalence (%)	0.03	0.01	0.03
Median age at first event (years)	55.82	56.57	55.59

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
92: Matched controls
920

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S98.1

ICD-10 Finland

Traumatic amputation of one toe

+∞

58.8

S98.2

ICD-10 Finland

Traumatic amputation of two or more toes

+∞

32.2

NHQ40

NOMESCO Finland

Amputation of toe

59.3

25.5

QDB10

NOMESCO Finland

Major dressing of wound of skin of lower limb

17.6

15.9

QDB05

NOMESCO Finland

Revision of wound of skin of lower limb

20.2

14.8

QDG20

NOMESCO Finland

Operation for chronic ulcer or fistula of skin of lower limb

+∞

13.9

W31

ICD-10 Finland

Contact with other and unspecified machinery

21.3

13.2

A46

ICD-10 Finland

Erysipelas

5.8

12.9

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

13.2

12.0

SPAT1148

SPAT

Treatment of chronic ulcer or burn

5.9

11.8

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

6.6

11.7

NHQ30

NOMESCO Finland

Amputation of foot, transmetatarsal

61.7

9.9

L97

ICD-10 Finland

Ulcer of lower limb, not elsewhere classified

16.0

9.6

NHQ48

NOMESCO Finland

Revision of amputation of toe

+∞

9.5

SPAT1149

SPAT

Suture or treatment of traumatic wound

4.6

8.2

I70.2

ICD-10 Finland

Atherosclerosis of arteries of extremities

4.9

8.0

SPAT1229

SPAT

Assessment of need for aid

10.3

7.9

WX213

NOMESCO Finland

Lower leg blockade

+∞

7.4

S97

ICPC

Chronic ulcer skin

7.5

7.0

S92.5

ICD-10 Finland

Fracture of other toe

18.5

6.9

NGQ20

NOMESCO Finland

Amputation of lower leg

43.4

6.9

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

9.9

6.8

J01FF01

ATC

clindamycin; systemic

3.3

6.6

146

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

3.2

6.5

160

M86.9

ICD-10 Finland

Osteomyelitis, unspecified

28.9

6.3

S98.3

ICD-10 Finland

Traumatic amputation of other parts of foot

+∞

6.3

S98.4

ICD-10 Finland

Traumatic amputation of foot, level unspecified

+∞

6.3

S91.3

ICD-10 Finland

Open wound of other parts of foot

16.4

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

4.14

7.64

3.2

1.7

—

(3009508) Creatinine [Moles/volume] in Urine

222

2.88

5.80

3.2

3.0

7.13

8.37

mmol/l

1.11

190

(3042936) Bacteria identified in Isolate by Culture

3.20

5.27

3.7

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

12.35

4.88

1.1

1.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

225

2.48

4.30

3.9

3.7

13.20

10.85

mg/mmol

0.13

148

(3012516) Albumin [Mass/volume] in Urine

207

2.42

3.99

3.3

3.1

108.32

402.81

mg/l

0.45

140

(3000093) Morphology [Interpretation] in Blood Narrative

8.72

2.78

1.0

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.07

2.53

1.3

2.0

—

(3022217) INR in Platelet poor plasma by Coagulation assay

360

1.93

2.46

21.7

13.8

1.23

1.25

inr

0.08

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.88

2.42

1.1

1.6

—

(3023368) Bacteria identified in Blood by Culture

196

1.97

2.32

6.5

4.6

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

4.12

2.30

1.4

1.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

205

1.95

2.29

2.8

3.2

2471.96

1064.73

ng/l

0.40

176

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.34

1.85

1.2

—

(3016879) Cocaine [Presence] in Urine

2.73

1.70

1.6

1.5

—

(3044640) Blood type and Crossmatch panel - Blood

234

1.72

1.63

7.4

2.1

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

291

1.66

1.55

3.7

3.6

52.22

44.47

ng/l

0.10

202

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

112

1.88

1.50

1.6

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.72

1.39

1.8

—

(3000764) Benzodiazepines [Presence] in Urine

2.48

1.33

1.8

1.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.48

1.33

1.9

1.6

—

(3027008) Opiates [Presence] in Urine

2.41

1.30

1.8

1.5

—

(3028300) Cannabinoids [Presence] in Urine

2.41

1.30

1.8

1.5

—

(3006315) Basophils [#/volume] in Blood

349

1.57

1.29

6.1

6.0

0.04

e9/l

0.46

303

(40768797) Stomach Pathology biopsy report

1.85

1.27

1.4

1.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

239

1.59

1.26

2.2

65.69

71.13

nmol/l

0.56

209

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

341

1.56

1.26

5.1

2.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

323

1.55

1.24

10.7

6.8

1.20

mmol/l

0.01

275

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

103

1.80

1.23

2.2

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.08

1.16

1.3

1.5

—

(3019198) Lymphocytes [#/volume] in Blood

366

1.51

1.13

6.3

6.1

1.77

1.82

e9/l

0.18

324

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.46

1.10

1.4

1.8

—

(3001604) Monocytes [#/volume] in Blood

349

1.50

1.09

6.1

5.9

0.64

0.61

e9/l

0.52

302

(3027944) Amphetamines [Presence] in Urine

2.08

1.02

1.6

1.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

411

1.47

1.02

9.8

10.3

4.77

4.20

e9/l

0.39

356

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

171

1.55

0.96

4.5

1.9

—

(4034850) Laboratory test

2.22

0.93

12.2

15.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

254

1.47

0.92

1.5

1.8

85.63

91.34

pmol/l

—

115

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

104

1.65

0.92

3.0

1.9

1.38

1.60

0.38

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

192

1.49

0.88

1.5

1.7

1.32

1.43

mmol/l

0.32

169

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

439

1.42

0.88

2.7

3.0

—

(1761868) Lipid panel - Serum or Plasma

302

0.68

0.80

3.3

2.7

—

(3044889) 12 lead EKG panel

514

1.41

0.80

3.8

3.7

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.80

0.0

1.8

—

4.43

—

(40768800) Prostate Pathology biopsy report

0.00

0.80

0.0

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.82

0.78

4.7

6.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.74

0.77

1.3

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

282

1.39

0.74

3.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

479

1.37

0.72

4.0

3.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.72

0.70

1.4

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.68

0.68

1.4

1.5

—

(3026008) Bacteria identified in Urine by Culture

166

1.43

0.67

2.6

2.2

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.76

0.65

4.2

2.1

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.61

0.0

2.3

—

69.64

—

(40768804) Tissue Pathology biopsy report

257

0.72

0.60

1.7

2.0

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

246

0.71

0.60

1.5

2.9

0.48

0.71

ug/l

—

157

(3022313) Gas panel - Capillary blood

1.66

0.57

5.0

2.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.50

0.56

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.48

0.54

2.4

1.7

—

(3013512) EKG study

191

1.35

0.54

5.5

4.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.53

0.52

1.5

2.7

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

306

1.29

0.51

8.6

5.9

1.20

mmol/l

0.08

283

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.51

0.51

4.0

2.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

129

1.39

0.50

1.2

1.3

3.34

2.56

g/l

—

(3023520) Reticulocytes [#/volume] in Blood

1.50

0.48

5.3

2.4

81.43

78.76

e9/l

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

704

1.35

0.47

4.8

4.4

6.33

6.06

mmol/l

0.89

651

(40761535) Cells panel - Urine sediment

1.46

0.47

2.7

3.2

—

(3021589) Normoblasts [#/volume] in Blood

309

1.27

0.47

8.8

10.0

0.00

e9/l

0.62

254

(46235355) HIV 1 and 2 tests - Meaningful Use set

123

1.36

0.44

2.6

1.9

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

685

1.32

0.44

7.9

5.4

41.74

40.52

mmol/mol

0.41

647

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.59

0.43

2.2

1.4

—

(3019225) pH of Specimen

1.39

0.42

17.5

3.8

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

511

1.25

0.42

4.9

3.0

63.43

51.56

u/l

0.36

485

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

362

1.24

0.41

3.3

0.00

estimate

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

152

1.32

0.41

2.9

3.3

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.41

0.0

1.6

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.4

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.41

0.0

1.3

—

633.94

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.40

0.0

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

335

1.23

0.38

10.4

6.7

—

(4200892) Spirometry reversibility

1.29

0.31

1.4

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

112

1.29

0.30

3.0

3.2

2.39

2.45

mmol/l

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

792

1.33

0.29

22.7

15.5

87.32

82.48

umol/l

0.31

792

(3000991) Gas panel - Venous blood

1.32

0.29

6.6

9.1

—

(3035350) Ketones [Presence] in Urine by Test strip

353

1.18

0.28

3.6

3.3

0.00

0.01

estimate

—

(40761511) CBC panel - Blood by Automated count

771

1.29

0.28

22.5

12.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

729

1.24

0.28

24.7

13.1

23.14

25.07

mg/l

0.23

565

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

415

0.86

0.26

3.5

4.6

1.69

1.86

ug/l

0.23

370

(3000492) Spirometry study

1.20

0.25

1.6

1.5

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.33

0.23

1.0

2.7

122.00

131.63

g/l

—

(3002385) Erythrocyte distribution width [Ratio]

640

0.86

0.22

26.0

16.2

16.37

15.19

0.51

630

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.5

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.5

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

59.94

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.28

0.21

12.0

8.1

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.7

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.7

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.7

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.7

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.5

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.5

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.24

0.20

3.7

10.5

94.70

93.50

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.8

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.20

0.0

1.2

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.21

0.20

1.7

3.0

64.03

67.92

g/l

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.21

0.20

2.3

3.0

—

60.72

—

(36660697) Celiac disease serology panel - Serum

1.19

0.20

1.0

1.2

—

(3000494) Fungus identified in Specimen by Culture

1.26

0.19

1.5

1.4

—

(3019060) Gas panel - Arterial blood

1.16

0.19

2.3

4.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

119

1.21

0.19

1.9

1.6

1979.60

1263.30

nmol/l

—

(3022621) pH of Urine by Test strip

1.18

0.18

3.6

2.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.16

0.18

2.3

1.9

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

120

1.20

0.17

3.0

2.4

1.16

0.96

e6/l

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.12

0.16

4.4

3.9

242.50

236.85

u/l

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.12

0.16

3.6

2.5

2.52

1.92

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.23

0.16

2.0

1.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

356

1.11

0.15

4.6

4.4

0.00

estimate

—

(36304419) Bacteria [Presence] in Urine

200

0.88

0.14

4.4

2.6

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

499

1.10

0.12

3.9

3.2

14.71

14.73

pmol/l

0.02

456

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.18

0.12

4.1

7.8

105.55

103.64

mmol/l

0.37

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

261

1.10

0.12

3.6

2.9

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

145

1.13

0.10

1.2

1.7

1.69

1.18

mg/l

0.25

123

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.14

0.10

8.2

4.4

22.96

24.85

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.17

0.10

2.0

1.7

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

326

0.93

0.08

3.5

4.3

24.80

21.02

—

151

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

686

1.09

0.07

18.0

12.6

80.60

82.89

ml/min/173m2

0.32

570

(21494755) Public health laboratory ask at order entry panel

0.86

0.07

1.4

1.5

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

227

1.08

0.06

2.8

3.1

2.29

2.34

mmol/l

0.59

197

(3018095) Leukocytes [#/volume] in Urine

263

0.93

0.06

4.3

3.3

98.53

49.92

e6/l

0.36

196

(3003694) ABO and Rh group [Type] in Blood

198

1.08

0.06

1.3

1.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

120

0.91

0.05

4.3

2.3

11.11

14.25

umol/l

0.99

113

(3023103) Potassium [Moles/volume] in Serum or Plasma

769

0.93

0.03

27.1

14.7

4.04

4.00

mmol/l

0.63

746

(40758558) Short blood count panel - Blood

191

1.06

0.03

6.0

6.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

118

0.92

0.03

3.3

2.5

1.06

1.02

e6/l

—

(3030467) Casts [#/volume] in Urine by Automated count

203

1.04

0.01

4.0

2.8

0.25

0.44

e6/l

0.63

151

(3041096) Erythrocytes [Presence] in Urine by Automated

217

1.02

0.00

3.1

2.9

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

765

0.96

0.00

27.0

14.7

139.16

139.68

mmol/l

1.13

745

(3026782) Osmolality of Urine

155

0.96

0.00

3.3

2.8

451.10

587.16

mosm/kgh2o

—

135

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

144

0.97

0.00

2.3

1.8

481.64

434.68

pmol/l

0.21

127

(3002582) Erythrocytes [#/volume] in Urine

234

0.98

0.00

3.9

2.9

19.27

302.38

e6/l

0.53

183

(3035941) MCH [Entitic mass]

829

1.01

0.00

33.7

19.3

30.43

0.01

818

(3000963) Hemoglobin [Mass/volume] in Blood

829

1.01

0.00

34.3

19.5

134.76

139.68

g/l

1.59

817

(3007461) Platelets [#/volume] in Blood

829

1.01

0.00

33.9

19.4

248.01

240.43

e9/l

0.47

809

(40761536) Microorganisms panel - Urine sediment

1.02

0.00

2.5

4.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

829

1.01

0.00

33.8

19.5

40.86

41.05

0.11

786

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3022145) Colonoscopy Study observation

0.90

-0.00

1.1

1.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.4

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.2

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.7

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.5

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.2

—

10.50

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

5.4

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.9

—

179.11

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.7

—

4.19

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

7.0

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

3.5

—

(3045424) Erythrocytes [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

2.2

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

2.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.1

—

101.19

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

1.51

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

285.29

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.8

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

15.20

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

2.0

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

14.40

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.7

—

106.50

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.0

—

(3034426) Prothrombin time (PT)

0.00

-0.00

0.0

1.2

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

4.6

—

52.00

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.92

-0.00

2.0

1.6

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3029937) Albumin [Presence] in Urine by Test strip

190

1.00

-0.00

3.9

3.6

0.00

estimate

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.92

-0.00

2.2

1.7

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

16.22

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

8.4

—

0.57

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

5.99

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

3.69

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.1

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

3.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

0.97

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.5

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.3

—

335.71

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

205.67

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.6

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.7

—

(3024731) MCV [Entitic volume]

828

1.02

-0.00

33.7

19.4

91.58

90.97

0.63

817

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

-0.00

0.0

2.0

—

(3002256) Pathology report gross observation

0.96

-0.00

1.1

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_AMPUT_ANKLE_FOOT – Traumatic amputation of ankle and foot

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic amputation of ankle and foot

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic amputation of ankle and foot (ST19_TRAUMAT_AMPUT_ANKLE_FOOT)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints