No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
398 |
6. Filter based on genotype QC (FinnGen only) |
398 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D80-D89
- Name in latin
- Aliae deficientiae immunales
Similar endpoints
↥List of similar endpoints to
Other immunodeficiencies
based on the number of shared cases.
Similar with more cases:
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2645 | 1656 | 973 |
| Only index persons | 2220 | 1431 | 789 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 45.52 | 47.81 | 41.32 |
| Only index persons | 45.60 | 47.13 | 42.83 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 398 | 269 | 129 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.06 |
| Median age at first event (years) | 47.84 | 46.20 | 51.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 352
- Matched controls
- 3519
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
111.5
101
*
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
94.1
86
*
D84.1
ICD-10 Finland
Defects in the complement system
+∞
68.0
63
*
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
62.4
58
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.1
45.3
224
895
T78.3
ICD-10 Finland
Angioneurotic oedema
38.9
44.5
56
17
H02AB06
ATC
prednisolone; systemic
5.1
44.5
244
1080
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
13.7
41.4
74
67
D84.8
ICD-10 Finland
Other specified immunodeficiencies
+∞
37.1
35
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
15.4
36.9
62
48
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
35.0
33
*
D84.0
ICD-10 Finland
Lymphocyte function antigen-1 [LFA-1] defect
+∞
35.0
33
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
33.9
32
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
33.9
32
*
D84.11
ICD-10 Finland
Hereditary angioedema type I
+∞
33.9
32
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
32.8
31
*
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
32.8
31
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.2
31.2
154
550
ZX120
NOMESCO Finland
Intravenous
6.8
31.1
85
157
R03DC03
ATC
montelukast; oral
4.8
30.8
122
350
338
Kela drug reimbursment
C1-esterase inhibitor, icatibant and conestat alfa
+∞
29.6
28
*
J45.9
ICD-10 Finland
Asthma, unspecified
4.7
28.9
115
329
C01CA24
ATC
epinephrine; parenteral
7.0
28.2
74
128
TPH04
NOMESCO Finland
Cathetrisation of vein
4.3
27.9
126
406
D84.13
ICD-10 Finland
Hereditary angioedema type III
+∞
27.5
26
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
6.8
27.2
73
130
J01MA14
ATC
moxifloxacin; systemic
6.8
26.3
70
123
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.1
25.9
120
391
B06AC02
ATC
icatibant; parenteral
+∞
25.3
24
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
9.8
25.1
52
61
J45.0
ICD-10 Finland
Predominantly allergic asthma
5.5
24.7
79
175
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.7
24.4
48
51
J01MA12
ATC
levofloxacin; systemic
4.3
24.2
104
314
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.5
23.9
143
572
R03AC02
ATC
salbutamol; inhalant
3.2
23.8
240
1400
H02AB07
ATC
prednisone; oral
4.6
23.6
93
257
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
16.2
23.6
38
26
WW200
NOMESCO Finland
Immunization
11.0
22.8
44
45
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.7
22.6
60
104
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
22.1
21
*
XQ800
NOMESCO Finland
Prick test
5.5
21.9
69
149
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.4
21.5
88
250
UJF32
NOMESCO Finland
Coloscopy
3.5
20.9
121
461
J45.1
ICD-10 Finland
Nonallergic asthma
5.6
20.5
63
131
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.1
20.5
52
84
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.6
20.0
109
394
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.2
19.3
54
100
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
19.0
88
278
J47
ICD-10 Finland
Bronchiectasis
18.9
18.6
28
16
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
6.6
18.5
49
84
6BA02
NOMESCO Finland
NA
55.6
18.2
21
*
R06.0
ICD-10 Finland
Dyspnoea
3.2
17.8
113
452
B02AA02
ATC
tranexamic acid; systemic
3.5
17.7
96
343
R50.9
ICD-10 Finland
Fever, unspecified
3.5
17.4
92
320
J31.0
ICD-10 Finland
Chronic rhinitis
4.9
17.3
59
138
J01FA06
ATC
roxithromycin; oral
2.7
16.9
170
909
J01MA02
ATC
ciprofloxacin; systemic
2.7
16.9
156
793
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
16.6
105
418
Z31.5
ICD-10 Finland
Genetic counselling
5.7
16.2
48
95
R03BB04
ATC
tiotropium bromide; inhalant
5.1
16.1
53
119
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.9
15.7
53
122
UJF30
NOMESCO Finland
Ileoscopy through colon
4.5
15.7
59
152
J01FF01
ATC
clindamycin; systemic
2.8
15.6
125
575
TGC00
NOMESCO Finland
Bronchial lavation
13.9
15.4
26
20
H02AB09
ATC
hydrocortisone; systemic
8.0
15.4
35
48
R03BA05
ATC
fluticasone; inhalant
3.1
15.3
101
409
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
15.1
163
890
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
15.0
219
1400
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
14.8
57
150
H02AB04
ATC
methylprednisolone; systemic
3.3
14.6
83
302
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
9.8
14.5
29
32
R03AK07
ATC
formoterol and budesonide; inhalant
2.9
14.0
98
412
X57
ICD-10 Finland
Unspecified privation
12.8
13.8
24
20
UJF92
NOMESCO Finland
Capsular endoscopy
11.6
13.7
25
23
D84.12
ICD-10 Finland
Hereditary angioedema type II
+∞
13.6
13
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.2
13.6
80
298
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
13.6
103
453
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.3
13.2
51
134
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
7.4
13.2
31
45
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.7
13.1
110
513
R06AX27
ATC
desloratadine; oral
2.5
13.0
135
708
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.7
13.0
60
186
A02BC01
ATC
omeprazole; systemic
2.6
12.9
112
532
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.0
12.8
54
154
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
12.3
129
674
R03DA04
ATC
theophylline; systemic, rectal
6.4
12.3
32
54
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.3
12.1
46
119
R01AD09
ATC
mometasone; nasal
2.2
12.0
183
1145
J05AB11
ATC
valaciclovir; oral
3.3
12.0
63
215
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
11.9
71
265
R01AD08
ATC
fluticasone; nasal
2.4
11.9
129
684
R03AK08
ATC
formoterol and beclometasone; inhalant
6.9
11.8
29
45
A07AA02
ATC
nystatin; oral
5.3
11.8
36
74
N02AX02
ATC
tramadol; systemic, rectal
2.3
11.8
154
894
R03AC12
ATC
salmeterol; inhalant
6.1
11.8
32
57
R4110
NOMESCO Finland
Physiotherapy
2.4
11.7
117
595
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
67.3
11.7
13
*
R06AE07
ATC
cetirizine; oral
2.2
11.6
182
1148
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
11.6
51
151
ZXA10
NOMESCO Finland
Bilateral
2.8
11.6
83
350
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
11.5
87
378
J45
ICD-10 Finland
Asthma
3.5
11.5
56
181
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
15.7
11.4
18
12
J01FA10
ATC
azithromycin; systemic
2.2
11.4
232
1639
R03BA02
ATC
budesonide; inhalant
2.7
11.4
86
371
C03CA01
ATC
furosemide; systemic
2.6
11.0
92
422
R03BA08
ATC
ciclesonide; inhalant
4.0
11.0
45
125
A01AB09
ATC
miconazole; local oral
3.8
10.9
48
142
L04AB04
ATC
adalimumab; parenteral
11.1
10.9
20
19
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.7
10.9
37
86
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
18.6
10.8
16
9
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
22.3
10.8
15
7
R06AE09
ATC
levocetirizine; oral
2.7
10.7
78
332
N03AX16
ATC
pregabalin; oral
2.5
10.6
92
432
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.5
10.5
37
89
B06AC05
ATC
lanadelumab; parenteral
+∞
10.5
10
*
B06AC01
ATC
c1-inhibitor, plasma derived; parenteral
+∞
10.5
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.0
10.4
33
71
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
10.2
71
291
K50.9
ICD-10 Finland
Crohn disease, unspecified
10.5
10.1
19
19
R60.9
ICD-10 Finland
Oedema, unspecified
5.1
10.1
31
65
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
41.3
10.0
12
*
R60.0
ICD-10 Finland
Localized oedema
3.2
10.0
55
193
A02BC03
ATC
lansoprazole; oral
2.3
10.0
110
579
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
17.3
10.0
15
9
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.5
9.8
34
81
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
9.8
82
373
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
9.7
107
562
J46
ICD-10 Finland
Status asthmaticus
7.0
9.6
23
35
XG410
NOMESCO Finland
Flow-volume spirometry
5.2
9.5
29
60
E0000UV
ATC
NA
2.1
9.4
159
1005
C07AB07
ATC
bisoprolol; oral
2.1
9.4
142
856
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
9.4
9
*
WZC30
NOMESCO Finland
Teaching
2.8
9.4
62
247
L04AX01
ATC
azathioprine; systemic
5.2
9.3
28
57
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.2
9.3
120
675
T78.4
ICD-10 Finland
Allergy, unspecified
4.1
9.3
36
96
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.5
9.2
32
77
N02AA05
ATC
oxycodone; systemic
3.0
9.1
53
194
J45.8
ICD-10 Finland
Mixed asthma
5.5
9.1
26
50
R03BB01
ATC
ipratropium bromide; inhalant
6.1
9.1
24
42
B01AB05
ATC
enoxaparin; parenteral
2.2
9.1
103
548
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.0
9.0
192
1323
R51.80
ICD-10 Finland
Headache
2.5
8.9
73
330
N06AX21
ATC
duloxetine; oral
3.0
8.9
52
192
A02BC02
ATC
pantoprazole; systemic
2.0
8.8
218
1584
L50.8
ICD-10 Finland
Other urticaria
8.6
8.7
18
22
J32.4
ICD-10 Finland
Chronic pansinusitis
8.6
8.7
18
22
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
7.2
8.7
20
29
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
8.7
128
759
R01AD05
ATC
budesonide; nasal
3.4
8.6
41
130
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
16.8
8.6
13
8
R03AC03
ATC
terbutaline; inhalant
2.7
8.6
65
277
ZXA05
NOMESCO Finland
Left side
2.3
8.6
94
486
P01AB01
ATC
metronidazole; oral, rectal
2.0
8.6
149
941
A02BC05
ATC
esomeprazole; systemic
2.0
8.6
145
908
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.2
8.5
47
163
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
20.6
8.5
12
6
R06AX22
ATC
ebastine; oral
2.4
8.4
77
368
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
8.4
87
440
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
8.4
8
*
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
+∞
8.4
8
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
8.3
55
218
J01DA01
ATC
[U] cefalexin; systemic
2.0
8.3
223
1653
N05CF01
ATC
zopiclone; oral
2.1
8.3
113
647
P01BA02
ATC
hydroxychloroquine; oral
3.4
8.1
39
125
R4120
NOMESCO Finland
Occupational therapy
3.7
8.1
35
103
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
8.1
46
166
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
8.1
60
256
J01DA06
ATC
[U] cefuroxime; systemic
2.6
8.0
64
282
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.1
7.9
24
50
N02BE01
ATC
paracetamol; systemic, rectal
2.2
7.9
290
2401
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
7.9
90
476
L50.9
ICD-10 Finland
Urticaria, unspecified
4.2
7.9
29
74
N03AX12
ATC
gabapentin; oral
2.7
7.9
58
243
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
11.2
7.9
14
13
J01FA09
ATC
clarithromycin; systemic
2.0
7.9
127
774
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.8
7.8
32
90
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
7.7
81
410
4AA12
NOMESCO Finland
NA
46.0
7.7
9
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
46.0
7.7
9
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
7.7
75
368
R53
ICD-10 Finland
Malaise and fatigue
2.2
7.7
81
413
A02BA02
ATC
ranitidine; systemic
2.4
7.7
70
332
J06.80
ICD-10 Finland
Continuously repeating infections of a child
25.6
7.6
10
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.1
7.6
23
48
A07EA06
ATC
budesonide; oral, local oral
5.5
7.5
21
40
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
13.7
7.4
12
9
XW000
NOMESCO Finland
Bone marrow biopsy
4.7
7.4
24
54
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
5.1
7.4
22
45
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
7.4
42
151
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
11.2
7.4
13
12
A06AD11
ATC
lactulose; oral
2.7
7.3
52
213
E84.9
ICD-10 Finland
Cystic fibrosis, unspecified
+∞
7.3
7
*
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
+∞
7.3
7
*
G03XA01
ATC
danazol; oral
+∞
7.3
7
*
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
16.2
7.3
11
7
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
7.2
35
113
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
3.3
7.2
36
119
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
7.2
38
131
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
30.7
7.2
9
*
V18
ICD-10 Finland
Pedal cyclist injured in noncollision transport accident
30.7
7.2
9
*
R1250
NOMESCO Finland
Evaluation of functional capability
8.2
7.2
15
19
A09AA02
ATC
multienzymes (lipase, protease etc.)
9.1
7.1
14
16
J01DC02
ATC
cefuroxime; systemic
3.5
7.1
32
98
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
7.1
49
201
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.8
7.0
22
48
J01AA02
ATC
doxycycline; systemic
1.9
7.0
257
2062
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.6
6.9
51
216
J01DB01
ATC
cefalexin; oral
2.0
6.9
286
2392
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
6.9
65
312
K50.0
ICD-10 Finland
Crohn disease of small intestine
8.5
6.9
14
17
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.6
6.8
29
85
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
6.8
49
203
A46
ICD-10 Finland
Erysipelas
2.6
6.8
49
203
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
17.1
6.8
10
6
R03BA01
ATC
beclometasone; inhalant
2.5
6.7
55
247
7151E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, LONKKANIVEL]
23.0
6.7
9
*
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
6.1
6.7
17
29
A01
ICPC
Pain general/multiple sites
3.2
6.7
33
109
J01FA15
ATC
telithromycin; oral
2.8
6.7
42
162
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.9
6.6
26
71
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
6.6
85
468
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
12.6
6.6
11
9
WX002
NOMESCO Finland
Sedation and analgesia
2.2
6.6
72
371
A07EC02
ATC
mesalazine; oral, rectal
3.4
6.6
30
93
N06AA09
ATC
amitriptyline; systemic
2.9
6.6
39
146
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
6.5
67
333
J02AC01
ATC
fluconazole; systemic
1.8
6.5
151
1029
J01CA04
ATC
amoxicillin; systemic
2.0
6.5
293
2493
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
6.5
45
184
ZXA00
NOMESCO Finland
Right side
2.0
6.5
94
543
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
7.6
6.5
14
19
D07AB08
ATC
desonide; topical
2.6
6.5
45
185
D86.0
ICD-10 Finland
Sarcoidosis of lung
71.1
6.4
7
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
71.1
6.4
7
*
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
71.1
6.4
7
*
M25.5
ICD-10 Finland
Pain in joint
1.9
6.4
111
685
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
14.7
6.4
10
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
6.4
30
95
C03DA01
ATC
spironolactone; oral
2.9
6.4
38
142
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
8.4
6.4
13
16
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
8.4
6.4
13
16
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
6.4
57
266
TAB00
NOMESCO Finland
Lumbar puncture
3.7
6.4
26
74
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.5
6.3
21
49
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
9.5
6.3
12
13
L04AA01
ATC
[U] ciclosporin; systemic
9.5
6.3
12
13
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
6.3
24
64
X58
ICD-10 Finland
Exposure to other specified factors
2.3
6.3
57
269
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.6
6.3
20
45
E84.1
ICD-10 Finland
Cystic fibrosis with intestinal manifestations
+∞
6.3
6
*
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
6.3
6
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
6.3
6
*
D84.14
ICD-10 Finland
C1 esterase inhibitor deficiency (C1-INH deficiency)
+∞
6.3
6
*
304
Kela drug reimbursment
Dornase alfa
+∞
6.3
6
*
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
6.3
6
*
J01XB01
ATC
colistin; inhalant, parenteral
+∞
6.3
6
*
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
+∞
6.3
6
*
L04AA06
ATC
mycophenolic acid; systemic
6.5
6.2
15
24
N06AX11
ATC
mirtazapine; oral
1.9
6.2
111
694
N05BB01
ATC
hydroxyzine; systemic
3.5
6.2
27
81
602
Kela drug reimbursment
Children's severe malnutrition
7.9
6.2
13
17
M54.3
ICD-10 Finland
Sciatica
3.6
6.2
26
76
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
6.1
159
1119
ZX108
NOMESCO Finland
Inhalation
12.8
6.1
10
8
S97
ICPC
Chronic ulcer skin
4.0
6.1
23
61
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
6.1
120
774
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.4
6.1
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
130
113
16.60
133.56
2.7
1.5
0.2
0.2
g/l
2.14
113
113
83
25
41.68
133.26
2.6
2.0
—
—
—
0
0
180
263
11.67
129.40
8.3
2.4
9.6
9.8
g/l
0.29
173
240
164
214
12.33
128.35
3.9
1.7
1.4
1.3
g/l
0.14
151
198
151
232
9.88
102.04
2.2
1.2
321.6
225.0
u/ml
0.29
145
212
68
31
26.25
94.34
2.5
1.8
0.2
0.2
e9/l
0.30
61
22
68
32
25.42
93.15
2.5
1.7
605.4
684.1
e6/l
0.21
61
22
52
10
59.66
91.83
3.5
1.2
644.2
1119.1
u/ml
—
52
10
46
10
51.88
78.98
1.3
1.0
—
—
—
0
0
34
12
30.89
50.90
2.0
1.8
12.1
11.9
u/l
0.04
34
12
53
65
9.25
41.16
4.2
2.5
—
—
—
0
0
35
25
15.25
38.68
2.0
2.6
35.8
43.3
%
—
11
6
105
275
4.83
38.27
4.6
3.2
0.2
0.2
g/l
0.59
99
262
323
1925
4.60
34.72
18.2
9.5
4.0
3.9
e9/l
0.32
312
1665
103
308
4.16
31.10
2.3
1.6
—
—
—
0
0
103
308
4.16
31.10
2.7
1.7
—
—
—
0
0
124
425
3.79
30.80
3.2
1.8
—
—
—
0
0
45
69
7.23
28.73
2.3
1.5
—
—
—
0
0
78
208
4.42
27.21
2.6
1.6
—
—
—
0
0
43
71
6.67
25.57
2.8
1.6
—
—
—
0
0
98
329
3.63
24.60
3.3
2.1
331.1
372.1
nmol/l
1.06
93
306
28
29
10.31
24.38
6.6
4.2
—
—
—
0
0
25
22
12.06
24.24
2.3
1.5
—
—
—
0
0
233
1312
2.87
23.37
3.8
2.5
77.2
75.7
nmol/l
0.33
221
1184
206
1112
2.77
22.03
6.3
3.2
—
—
—
0
0
100
374
3.24
20.86
4.1
2.7
19.8
22.3
%
1.17
91
324
32
49
7.01
20.33
4.6
3.2
4.2
4.4
e9/l
0.21
32
49
51
122
4.65
20.19
1.5
1.3
0.4
1.4
u/ml
—
11
7
155
751
2.74
20.10
4.7
2.3
2.9
3.1
mg/l
0.46
149
653
32
50
6.87
19.95
2.1
1.5
—
—
—
0
0
230
1357
2.65
19.94
14.7
7.0
1.2
1.2
mmol/l
3.32
215
1241
31
47
7.07
19.87
1.9
1.3
—
—
—
0
0
114
474
2.97
19.68
7.7
4.5
0.8
0.8
mmol/l
2.19
109
449
32
51
6.74
19.58
4.6
3.5
59.1
57.1
%
0.30
32
51
332
2395
3.33
18.91
17.3
7.0
79.9
81.7
u/l
0.33
324
2247
28
40
7.45
18.90
2.2
1.4
—
—
—
0
0
252
1584
2.61
18.69
10.3
6.2
11.0
12.1
umol/l
0.47
240
1494
31
51
6.51
18.40
2.2
1.6
—
—
—
0
0
50
129
4.29
17.95
2.2
1.6
—
—
—
0
0
239
1489
2.51
17.69
12.9
7.3
1.2
1.2
mmol/l
1.30
211
1277
23
28
8.66
17.68
3.0
1.1
1.4
0.1
u/ml
—
15
9
208
1223
2.47
17.39
10.0
4.8
35.7
36.3
g/l
0.94
199
1147
265
1766
2.50
16.42
10.0
4.8
6.3
6.5
mmol/l
0.93
258
1626
161
864
2.45
16.19
5.3
3.0
0.5
0.4
e6/l
0.18
135
632
25
38
6.95
15.94
2.2
1.5
—
—
—
0
0
33
67
5.28
15.75
1.2
1.4
—
—
—
0
0
33
67
5.28
15.75
1.2
1.4
—
—
—
0
0
324
2403
2.87
15.62
11.2
3.9
12.5
10.3
mm/h
2.28
314
2231
21
27
8.16
15.43
3.0
2.0
—
—
—
0
0
135
690
2.45
14.90
4.1
3.3
1254.8
1056.5
ng/l
0.29
117
579
25
42
6.28
14.50
1.9
1.5
—
—
—
0
0
86
358
2.79
14.42
4.4
3.5
6.7
7.1
umol/l
0.08
73
313
107
509
2.51
13.65
3.9
3.0
1.7
2.5
e6/l
0.82
68
277
109
524
2.49
13.59
3.8
2.8
1.0
0.9
e6/l
0.17
70
289
22
35
6.59
13.42
2.0
1.5
—
—
—
0
0
17
20
8.83
13.34
4.2
3.9
25.5
25.8
umol/l
0.03
17
20
31
69
4.79
13.31
1.5
1.4
—
—
—
0
0
27
54
5.29
13.08
1.1
1.2
1.6
1.5
u/ml
—
9
21
41
115
3.86
13.08
3.3
2.1
—
—
—
0
0
131
700
2.30
12.76
2.8
2.1
0.9
1.1
mg/l
0.87
116
527
50
164
3.34
12.62
2.2
1.4
—
—
—
0
0
21
34
6.46
12.59
1.9
1.4
—
—
—
0
0
226
1515
2.14
12.29
4.6
2.8
99.3
97.9
ug/l
0.05
221
1413
36
97
3.98
12.13
4.5
2.0
2.9
3.0
g/l
0.17
26
83
21
36
6.10
11.92
3.0
1.8
—
—
—
0
0
26
55
4.99
11.83
1.1
1.1
—
—
—
0
0
37
104
3.82
11.75
4.5
1.9
—
—
—
0
0
37
104
3.82
11.75
4.5
1.9
6.9
7.3
g/l
0.45
27
86
37
104
3.82
11.75
4.5
1.9
5.4
3.7
g/l
0.97
26
81
34
91
3.99
11.55
5.5
2.3
2.4
0.7
g/l
0.76
27
83
36
101
3.82
11.46
2.0
2.5
1.2
1.5
g/l
1.07
27
92
26
57
4.81
11.35
1.2
1.2
3.8
3.6
u/ml
0.05
11
26
16
22
7.54
11.06
2.4
1.5
27.6
16.1
umol/l
0.64
16
22
73
320
2.57
10.87
11.9
5.7
1.9
1.7
mmol/l
0.12
62
245
34
96
3.78
10.73
4.8
2.0
9.4
9.8
g/l
0.15
27
89
35
103
3.63
10.40
1.4
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
80
3.97
10.24
2.6
5.8
0.3
0.4
u/ml
0.41
20
43
24
54
4.67
10.16
3.5
2.0
15.9
16.8
%
0.43
15
24
172
1097
2.00
10.11
2.3
1.9
94.1
97.5
pmol/l
0.42
101
557
142
846
2.05
10.09
3.6
2.1
120.2
186.9
u/l
2.80
135
805
33
96
3.66
9.97
1.9
1.5
0.7
0.1
iu/ml
0.46
15
16
64
277
2.56
9.74
8.9
8.6
1.9
1.2
mmol/l
0.88
51
215
19
36
5.49
9.73
1.2
1.2
—
—
—
0
0
99
522
2.19
9.63
3.7
3.4
476.1
364.1
ng/l
0.13
53
361
11
11
10.26
9.58
1.6
1.4
—
—
—
0
0
30
84
3.78
9.57
1.7
1.2
3.2
0.9
u/ml
—
5
5
156
996
1.93
8.87
4.6
3.1
2.3
2.4
mmol/l
2.57
142
888
58
252
2.52
8.73
7.8
6.3
1.5
1.4
mmol/l
0.12
44
184
62
281
2.43
8.52
9.6
8.5
5.2
5.1
kpa
0.15
57
268
62
281
2.43
8.52
9.6
8.5
11.6
12.4
kpa
0.60
57
269
112
653
2.00
8.20
1.8
1.5
22.2
20.7
nmol/l
0.45
99
559
27
79
3.59
8.10
4.4
3.7
24.6
24.6
mmol/l
0.01
27
69
17
35
5.03
7.95
2.3
1.5
—
—
—
0
0
144
930
1.86
7.68
3.8
2.4
56.7
55.9
u/l
0.10
138
858
14
25
5.77
7.59
3.6
1.9
—
—
—
0
0
14
25
5.77
7.59
3.6
1.9
—
—
—
0
0
14
25
5.77
7.59
3.6
1.9
—
—
—
0
0
27
85
3.33
7.26
1.8
1.2
7.6
33.0
u/ml
—
7
9
31
107
3.06
7.18
1.4
1.1
—
—
—
0
0
215
1595
1.76
7.01
5.7
3.4
0.0
0.0
estimate
0.00
42
311
30
103
3.07
7.01
1.7
1.2
1.7
3.1
u/ml
—
5
17
154
1039
1.79
6.98
5.3
3.2
21.1
30.3
ng/l
1.15
99
628
19
48
4.11
6.97
1.7
1.5
—
—
—
0
0
23
67
3.58
6.95
1.6
1.9
—
—
—
0
0
214
1595
1.74
6.79
7.7
4.8
0.0
0.0
estimate
0.50
42
311
25
79
3.31
6.69
1.7
1.6
76.1
102.7
u/ml
—
7
12
38
154
2.62
6.58
2.3
1.6
—
—
—
0
0
95
561
1.91
6.55
1.8
1.6
44186497.8
14017187.3
pmol/l
0.29
86
478
114
715
1.83
6.51
2.7
2.2
—
—
—
0
0
214
1612
1.71
6.39
5.8
3.5
0.0
0.0
estimate
0.00
43
303
21
61
3.58
6.37
2.9
2.1
127.6
133.7
g/l
0.51
16
42
25
82
3.19
6.31
1.5
1.3
—
—
—
0
0
37
155
2.53
6.00
6.4
7.5
8.9
9.3
kpa
0.59
37
145
57
289
2.13
5.98
5.5
3.2
—
—
—
0
0
16
40
4.13
5.95
2.2
4.0
36.2
127.5
u/ml
—
5
11
26
92
2.95
5.79
1.5
1.3
323.1
320.0
ug/g
0.02
13
49
116
756
1.75
5.73
5.3
2.8
9457.6
5844.5
umol/l
0.21
109
668
78
456
1.88
5.48
1.8
1.6
1404.5
1194.1
nmol/l
1.01
63
342
18
54
3.44
5.23
1.3
1.3
—
—
—
0
0
14
35
4.11
5.21
1.9
1.1
—
—
—
0
0
21
70
3.11
5.18
7.5
4.7
21.7
25.1
mg/l
0.35
16
54
21
70
3.11
5.18
7.5
4.7
109.9
147.2
mg/l
0.14
16
54
24
87
2.87
5.14
1.8
1.5
233.7
221.4
u/ml
0.06
15
52
365
3302
2.27
5.04
38.5
12.1
21.5
21.7
mg/l
0.04
314
2501
191
1457
1.60
4.99
5.2
4.0
—
—
—
0
0
300
2559
1.70
4.91
4.9
4.0
14.5
14.6
pmol/l
0.21
284
2360
17
52
3.37
4.80
1.6
1.4
5533.5
14413.4
e6/l
0.96
11
36
18
58
3.20
4.70
1.3
1.1
—
—
—
0
0
16
48
3.43
4.65
2.8
1.6
1.5
1.5
mmol/l
0.07
16
48
24
92
2.71
4.65
1.7
1.5
—
—
—
0
0
45
230
2.08
4.62
3.9
2.6
59.0
70.8
ml/min/173m2
1.12
21
95
12
30
4.09
4.47
2.1
1.5
33.5
33.1
pg
0.17
12
30
287
2447
1.62
4.42
4.8
3.5
—
—
—
0
0
359
3262
2.03
4.34
36.5
13.4
139.3
139.7
mmol/l
2.03
354
3169
10
22
4.64
4.32
1.1
1.2
—
—
—
0
0
15
46
3.35
4.23
1.2
1.1
—
—
—
0
0
41
210
2.06
4.20
15.2
6.5
23.9
24.0
mmol/l
0.03
36
199
359
3273
1.99
4.12
36.7
13.5
3.9
3.9
mmol/l
4.27
354
3170
51
287
1.89
4.01
20.7
16.1
1.1
1.3
inr
—
8
39
9
14
6.55
4.00
1.1
1.1
—
—
—
0
0
52
298
1.86
3.87
1.7
1.9
—
—
—
0
0
89
605
1.61
3.59
1.5
1.3
23.9
32.6
iu/ml
0.55
32
182
6
6
10.13
3.51
8.0
3.0
—
—
—
0
0
25
113
2.29
3.49
1.7
1.3
—
—
—
0
0
47
270
1.84
3.48
1.6
1.3
54.9
177.7
iu/ml
3.90
13
111
76
502
1.64
3.44
2.7
2.7
2.4
2.4
mmol/l
0.14
65
439
9
18
5.09
3.39
2.0
1.3
—
—
—
0
0
9
19
4.82
3.25
2.3
1.2
—
—
—
0
0
157
1231
1.45
3.21
6.2
3.5
—
—
—
0
0
8
15
5.42
3.20
2.1
1.3
—
—
—
0
0
10
29
3.51
3.06
2.5
1.2
—
—
—
0
0
8
16
5.08
3.06
2.1
1.3
—
—
—
0
0
107
786
1.49
3.02
5.9
3.9
30.3
10.3
mg/mmol
1.04
70
489
321
2901
1.55
3.00
27.4
10.9
86.4
86.8
ml/min/173m2
0.09
285
2349
111
823
1.48
2.99
2.1
1.7
—
—
—
0
0
11
35
3.20
2.95
1.5
1.2
—
—
—
0
0
11
35
3.20
2.95
1.5
1.2
—
—
—
0
0
10
30
3.39
2.92
2.5
1.3
—
—
—
0
0
111
827
1.47
2.91
1.6
1.6
1.4
1.4
mmol/l
0.01
102
719
7
13
5.46
2.88
1.0
1.1
—
—
—
0
0
7
13
5.46
2.88
1.4
1.5
—
—
—
0
0
11
36
3.11
2.83
1.5
1.2
—
—
—
0
0
11
36
3.11
2.83
1.5
1.2
—
—
—
0
0
11
36
3.11
2.83
1.5
1.2
—
—
—
0
0
10
31
3.28
2.79
1.0
1.1
—
—
—
0
0
9
23
3.98
2.79
1.7
1.2
—
—
—
0
0
9
23
3.98
2.79
1.2
1.1
—
—
—
0
0
7
14
5.07
2.74
1.4
1.5
—
—
—
0
0
119
909
1.44
2.72
1.5
1.4
0.8
1.6
u/ml
0.99
39
245
24
119
2.08
2.72
1.3
1.2
—
—
—
0
0
11
37
3.03
2.71
1.5
1.1
—
—
—
0
0
39
230
1.77
2.68
1.6
1.8
—
—
—
0
0
24
121
2.05
2.61
1.3
1.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
7
15
4.73
2.61
1.0
1.1
111.4
129.5
%
—
7
15
9
25
3.66
2.59
1.7
1.5
—
—
—
0
0
80
571
1.50
2.57
1.5
1.3
5.3
10.7
u/ml
0.83
31
223
13
50
2.65
2.55
4.4
2.8
0.4
1.2
%
1.24
13
42
20
97
2.12
2.41
1.2
1.2
0.5
4.6
u/ml
1.85
15
49
28
154
1.88
2.41
6.0
2.9
0.2
0.1
e6/l
0.40
28
149
8
22
3.69
2.37
1.3
1.2
—
—
—
0
0
43
272
1.65
2.32
4.0
4.1
10.8
48.4
ug/l
0.65
33
222
9
28
3.26
2.32
2.2
2.3
—
—
—
0
0
60
414
1.53
2.26
1.7
1.8
1.4
1.4
%
0.11
54
375
9
29
3.15
2.24
2.7
4.8
111.0
103.0
%
—
9
29
15
67
2.29
2.20
1.2
1.1
—
—
—
0
0
6
14
4.33
2.16
3.5
1.9
—
—
—
0
0
6
14
4.33
2.16
3.5
1.9
—
—
—
0
0
6
14
4.33
2.16
3.5
1.9
—
—
—
0
0
10
37
2.75
2.12
1.6
1.3
—
—
—
0
0
5
10
5.05
2.07
1.2
1.1
—
—
—
0
0
8
26
3.12
2.02
1.0
1.6
—
—
—
0
0
324
3010
1.41
1.93
5.9
4.6
1.8
2.3
mu/l
0.58
312
2796
7
23
3.08
1.80
2.9
2.5
—
—
—
0
0
22
125
1.80
1.76
1.4
1.4
9.9
11.0
u/l
0.15
17
89
6
18
3.37
1.75
6.2
1.8
—
—
—
0
0
6
18
3.37
1.75
6.2
1.8
—
—
—
0
0
6
18
3.37
1.75
6.2
1.8
—
—
—
0
0
9
36
2.53
1.75
1.0
1.4
—
—
—
0
0
105
841
1.34
1.74
7.5
3.7
0.0
0.0
estimate
0.50
42
309
13
62
2.13
1.67
2.1
1.5
—
—
—
0
0
19
325
0.56
1.67
1.6
1.6
—
—
—
0
0
7
25
2.83
1.65
1.4
1.1
—
—
—
0
0
7
25
2.83
1.65
1.4
2.8
13.3
23.5
ug/l
—
7
25
242
2178
1.28
1.64
5.8
3.2
47.5
41.2
u/l
0.90
232
2073
6
20
3.03
1.58
2.7
3.5
—
—
—
0
0
7
29
2.44
1.40
2.1
2.8
1.4
4.3
nmol/l
—
7
29
6
23
2.63
1.37
1.7
2.0
—
—
—
0
0
6
23
2.63
1.37
1.7
2.0
—
—
—
0
0
21
130
1.65
1.29
1.5
1.4
155.8
260.0
miu/ml
1.11
13
69
5
18
2.80
1.29
7.2
1.8
—
—
—
0
0
299
2800
1.27
1.28
6.5
5.0
39.5
38.8
mmol/mol
0.54
288
2642
16
92
1.77
1.27
5.3
1.8
—
—
—
0
0
6
26
2.33
1.19
6.2
2.9
—
—
—
0
0
31
216
1.47
1.18
1.4
1.3
—
—
—
0
0
8
154
0.51
1.16
1.3
1.4
—
—
—
0
0
33
237
1.43
1.09
1.2
1.3
—
36.9
—
0
13
280
2961
0.82
1.05
4.1
3.6
1.4
1.3
mmol/l
2.97
258
2760
32
231
1.42
1.03
1.1
1.0
—
—
—
0
0
325
3104
1.26
0.99
33.3
13.5
39.4
40.0
%
1.02
265
2451
6
30
2.01
0.87
1.2
1.1
—
79.0
—
0
6
294
3073
0.83
0.83
4.5
4.0
1.4
1.5
mmol/l
1.08
277
2870
19
130
1.48
0.82
2.1
1.8
—
—
—
0
0
6
32
1.89
0.82
1.8
1.3
—
—
—
0
0
18
127
1.44
0.69
1.6
1.5
—
—
—
0
0
15
102
1.49
0.68
6.9
1.9
—
—
—
0
0
26
329
0.78
0.57
11.7
6.1
—
—
—
0
0
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
20
152
1.33
0.53
2.6
1.4
7.4
2.9
mg/l
0.71
14
106
29
356
0.80
0.51
2.4
2.7
0.6
0.7
ug/l
0.32
20
219
5
82
0.60
0.46
1.6
1.5
—
—
—
0
0
304
3124
0.89
0.44
5.1
4.4
2.8
2.8
mmol/l
0.05
284
2916
5
31
1.62
0.43
4.0
1.7
—
—
—
0
0
5
32
1.57
0.42
3.2
1.5
—
—
—
0
0
5
32
1.57
0.42
3.2
1.5
—
—
—
0
0
5
32
1.57
0.42
3.2
1.5
—
—
—
0
0
5
33
1.52
0.41
3.2
1.5
—
—
—
0
0
5
33
1.52
0.41
3.2
1.5
—
—
—
0
0
22
179
1.24
0.38
3.0
2.3
1953.8
3159.0
u/l
—
5
64
292
2998
0.90
0.37
4.9
4.0
5.8
5.8
mmol/l
0.36
279
2786
6
43
1.40
0.35
1.5
1.2
—
—
—
0
0
43
487
0.87
0.35
3.0
4.1
21.9
21.8
%
0.01
13
212
10
73
1.38
0.35
1.3
1.2
—
—
—
0
0
18
221
0.81
0.34
1.4
1.5
—
—
—
0
0
6
46
1.31
0.33
1.2
1.5
5.7
7.0
mmol/l
—
6
31
302
3085
0.91
0.30
4.5
4.0
4.7
4.7
mmol/l
0.13
285
2892
8
107
0.74
0.29
2.0
1.6
—
—
—
0
0
8
63
1.28
0.28
1.4
1.5
—
—
—
0
0
8
66
1.22
0.27
1.9
2.5
2.4
5.6
u/ml
—
8
60
5
39
1.29
0.23
2.0
3.1
18.2
57.7
u/ml
—
5
39
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
118
0.84
0.14
1.4
1.4
—
—
—
0
0
10
118
0.84
0.14
1.4
1.4
—
—
—
0
0
10
118
0.84
0.14
1.4
1.4
—
—
—
0
0
10
118
0.84
0.14
1.4
1.4
—
—
—
0
0
49
461
1.07
0.14
2.3
2.0
—
—
—
0
0
58
607
0.95
0.11
4.0
4.6
1.5
2.4
ug/l
0.78
50
543
5
47
1.06
0.09
1.2
1.1
22.0
13.5
u/l
—
5
41
6
55
1.09
0.09
1.3
1.3
1.6
3.4
ug/l
—
6
48
5
60
0.83
0.08
1.8
1.6
—
—
—
0
0
53
511
1.04
0.07
2.4
2.2
—
—
—
0
0
64
626
1.03
0.04
1.7
1.5
—
—
—
0
0
12
129
0.93
0.03
1.3
1.5
—
—
—
0
0
13
132
0.98
0.00
2.4
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
7
70
1.00
0.00
1.6
1.5
36.4
22.1
u/l
—
7
57
0
5
0.00
0.00
0.0
1.0
—
65.2
—
0
5
8
79
1.01
0.00
1.4
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.6
—
2.2
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
9
93
0.97
0.00
1.6
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_IMMUDEFOTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_IMMUDEFOTHER | 1.966 [1.61, 2.4] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.164 |
During the follow-up period (1.1.1998 — 31.12.2019), 290 out of 1479 females with D3_IMMUDEFOTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_IMMUDEFOTHER | 2.078 [1.62, 2.67] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 187 out of 855 males with D3_IMMUDEFOTHER died.
Mortality risk
Mortality risk for people of age
years, who have D3_IMMUDEFOTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.147% | 0.391% |
| 5 | 1.014% | 2.209% |
| 10 | 2.58% | 5.648% |
| 15 | 5.512% | 10.441% |
| 20 | 9.694% | 17.119% |
Relationships between endpoints
↥Index endpoint: D3_IMMUDEFOTHER – Other immunodeficiencies
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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