tonsil cancer: Tumors or cancer of the PALATINE TONSIL.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
442 |
4. Check minimum number of eventsNone |
442 |
5. Include endpointsNone |
442 |
6. Filter based on genotype QC (FinnGen only) |
426 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum tonsillae palatinae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Tonsil
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2787 | 1600 | 1173 |
| Only index persons | 2614 | 1535 | 1079 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 56.41 | 55.74 | 57.29 |
| Only index persons | 55.84 | 55.41 | 56.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 426 | 253 | 173 |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.08 |
| Median age at first event (years) | 59.46 | 56.93 | 63.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 442
- Matched controls
- 4420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
+∞
307.7
427
*
EMB10
NOMESCO Finland
Tonsillectomy
12.3
82.5
90
90
EMA10
NOMESCO Finland
Biopsy of tonsil
200.6
81.2
82
5
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
23.2
59.2
44
21
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
137.4
46.8
49
*
C09.9
ICD-10 Finland
Malignant neoplasm: Tonsil, unspecified
237.5
42.7
43
*
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
201.4
36.3
37
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.1
35.2
67
126
ENA10
NOMESCO Finland
Biopsy of pharynx
189.5
34.2
35
*
130
Kela drug reimbursment
Malignant tumour
4.5
29.6
81
208
WF002
NOMESCO Finland
Radical radiotherapy
5.8
29.2
58
113
JDB10
NOMESCO Finland
Percutaneous gastrostomy
27.6
28.0
38
15
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.9
25.4
60
136
C09.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tonsil
231.0
21.8
22
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
21.0
146
666
R07.0
ICD-10 Finland
Pain in throat
4.4
19.6
52
129
J35.1
ICD-10 Finland
Hypertrophy of tonsils
14.5
18.0
30
22
EMB00
NOMESCO Finland
Excision of lesion of tonsil or adenoids
+∞
16.8
16
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
18.8
16.7
25
14
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
20.1
15.7
23
12
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
13.5
139
740
R4190
NOMESCO Finland
Nutritional therapy
4.8
13.5
31
68
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.3
13.0
51
166
R21
ICPC
Throat symptom/complaint
2.4
13.0
110
538
ZXE00
NOMESCO Finland
One hour or less
2.1
12.9
195
1205
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.5
12.7
46
142
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
+∞
12.6
12
*
8070/3-C09.0
ICD-O-3
Squamous cell carcinoma, NOS, of tonsillar fossa
+∞
12.6
12
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.2
12.2
34
87
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
18.7
12.1
18
10
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.9
12.0
37
102
A07AA02
ATC
nystatin; oral
3.6
12.0
41
122
A04AA02
ATC
granisetron; systemic, transdermal
3.3
11.7
47
155
J35.0
ICD-10 Finland
Chronic tonsillitis
4.2
11.4
31
78
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
10.0
11.4
22
23
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
11.0
175
1087
J39.2
ICD-10 Finland
Other diseases of pharynx
14.7
10.6
17
12
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
10.1
199
1321
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
4.9
9.9
22
47
EHA10
NOMESCO Finland
Biopsy of palate
18.0
9.5
14
8
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
18.0
9.5
14
8
21050
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Tonsil
+∞
9.4
9
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
22.3
9.4
13
6
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.7
9.1
29
82
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
9.1
182
1204
H02AB02
ATC
dexamethasone; systemic
2.4
8.5
65
301
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
8.1
8.4
18
23
ZX095
NOMESCO Finland
Combined chemoradiotherapy
13.1
8.4
14
11
N02AA05
ATC
oxycodone; systemic
2.1
8.4
91
485
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
8.4
32
102
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
8.8
8.4
17
20
R04.2
ICD-10 Finland
Haemoptysis
4.2
8.4
22
54
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.9
8.0
138
863
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.8
136
854
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
7.6
7.7
17
23
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
7.7
51
220
UJC01
NOMESCO Finland
Scopy of lower throat
8.3
7.7
16
20
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
7.6
61
288
Z2221
NOMESCO Finland
Medical doctor
1.8
7.3
131
826
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
7.3
7
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.7
7.2
23
65
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
7.2
313
2539
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
11.2
6.8
12
11
J35.9
ICD-10 Finland
Chronic disease of tonsils and adenoids, unspecified
40.7
6.8
8
*
K11.70
ICD-10 Finland
Hypoptyalism
22.9
6.7
9
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.9
6.6
91
526
A04AA01
ATC
ondansetron; systemic, rectal
2.5
6.5
43
186
A02BC05
ATC
esomeprazole; systemic
1.7
6.5
186
1334
D10.5
ICD-10 Finland
Benign neoplasm: Other parts of oropharynx
70.8
6.4
7
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
6.4
61
309
WZC30
NOMESCO Finland
Teaching
2.0
6.3
78
435
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
27.1
6.2
8
*
B37.0
ICD-10 Finland
Candidal stomatitis
7.8
6.2
13
17
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.4
6.1
22
68
J01CA04
ATC
amoxicillin; systemic
1.8
6.1
356
3058
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
137
636
2.67
18.79
1.6
1.5
—
—
—
0
0
127
596
2.59
16.80
5.1
3.2
0.80
0.82
mmol/l
1.27
118
563
40
99
4.34
15.05
1.3
1.2
—
—
—
0
0
253
1788
1.97
10.88
5.7
6.4
1.22
1.22
mmol/l
0.30
209
1522
192
1236
1.98
10.85
4.5
3.3
2.37
2.35
mmol/l
1.13
171
1092
263
1933
1.89
9.53
7.0
6.2
10.09
11.21
umol/l
1.89
257
1838
350
2843
2.11
9.31
9.7
7.5
76.38
77.70
u/l
0.32
340
2669
20
26
8.00
9.23
1.3
1.1
—
—
—
0
0
281
2135
1.87
8.90
12.4
9.4
3.94
4.10
e9/l
0.66
245
1898
218
1541
1.82
8.65
5.1
4.5
36.05
35.67
g/l
0.49
211
1445
225
1650
1.74
7.52
5.3
5.6
1.21
1.22
mmol/l
0.06
210
1515
126
790
1.83
7.15
1.3
1.2
0.56
1.95
u/ml
1.70
32
227
233
1760
1.68
6.71
7.8
6.1
27.10
28.00
%
0.60
221
1670
110
675
1.84
6.63
3.9
3.0
2.46
2.45
mmol/l
0.37
98
583
230
1737
1.68
6.59
7.5
5.9
57.60
57.11
%
0.23
218
1644
327
2752
1.72
5.85
5.0
4.1
12.62
11.73
mm/h
0.53
306
2530
143
983
1.67
5.68
3.4
2.9
0.36
0.43
e6/l
0.20
108
743
95
591
1.77
5.39
2.8
2.6
0.98
1.02
e6/l
0.04
53
335
392
3516
2.02
5.27
17.6
12.7
80.68
81.42
ml/min/173m2
0.28
343
2882
61
333
1.97
5.19
2.7
2.4
31.26
34.40
u/l
0.34
54
281
383
3423
1.89
5.00
5.8
4.7
1.96
2.23
mu/l
0.35
357
3137
89
557
1.75
4.92
3.2
2.8
1.79
2.27
e6/l
0.34
48
305
330
2840
1.64
4.82
5.0
3.9
14.63
14.78
pmol/l
0.51
309
2586
412
3790
2.28
4.76
19.6
15.8
139.57
139.67
mmol/l
0.35
403
3692
149
1075
1.58
4.73
3.7
3.0
30.26
128.41
e6/l
0.91
112
829
76
460
1.79
4.70
6.4
5.0
1.01
1.01
mmol/l
0.00
68
429
15
36
4.28
4.55
1.5
1.3
—
—
—
0
0
412
3801
2.24
4.54
19.8
15.8
3.95
3.97
mmol/l
0.78
402
3699
17
54
3.23
4.53
2.6
3.6
—
3883.86
—
0
7
190
1465
1.52
4.40
2.0
2.0
100.38
96.41
pmol/l
0.50
97
739
27
117
2.39
4.10
1.1
1.1
—
—
—
0
0
131
955
1.53
3.85
3.3
2.5
6529.38
6891.50
umol/l
0.03
117
830
7
8
8.87
3.78
1.1
1.8
—
—
—
0
0
36
185
2.03
3.65
1.3
1.3
—
—
—
0
0
188
1489
1.46
3.63
2.6
2.2
76.72
77.40
nmol/l
0.11
163
1326
166
1284
1.47
3.62
4.0
3.0
—
—
—
0
0
391
3599
1.75
3.52
5.0
4.6
5.88
5.96
mmol/l
0.65
362
3301
286
2468
1.45
3.39
3.2
3.1
48.53
49.08
u/l
0.03
267
2320
10
23
4.42
3.33
2.7
3.5
—
—
—
0
0
25
117
2.20
3.23
1.1
1.1
—
—
—
0
0
43
248
1.81
3.13
1.9
1.5
—
—
—
0
0
9
20
4.57
3.13
1.7
2.2
—
—
—
0
0
71
471
1.60
3.12
2.2
2.1
23.25
23.31
%
0.01
62
414
397
3695
1.73
3.09
19.0
13.6
20.41
22.58
mg/l
0.77
339
2923
253
2169
1.39
2.90
4.5
4.5
6.38
6.73
mmol/l
3.05
248
2019
54
341
1.66
2.88
2.8
2.0
388.69
368.66
nmol/l
0.35
49
313
107
792
1.46
2.84
1.7
1.8
0.87
1.18
mg/l
1.26
80
635
82
575
1.52
2.83
2.2
1.9
—
—
—
0
0
62
411
1.59
2.73
3.1
2.6
5.03
8.72
umol/l
2.97
54
367
114
861
1.44
2.71
2.3
2.0
3.30
3.22
mg/l
0.10
97
745
17
73
2.38
2.68
1.7
3.2
5.11
5.07
kpa
0.08
17
73
145
1150
1.39
2.60
2.5
2.4
54.43
61.38
u/l
0.87
134
1082
413
3921
1.81
2.52
21.8
16.1
76.91
76.06
umol/l
0.30
413
3921
55
362
1.59
2.51
3.7
3.3
—
—
—
0
0
203
1708
1.35
2.48
10.6
12.0
1.13
1.20
inr
0.69
66
484
40
244
1.70
2.44
1.3
1.2
83.61
153.68
iu/ml
1.01
15
105
71
501
1.50
2.38
2.1
2.1
2.43
2.37
g/l
0.40
63
464
13
52
2.55
2.38
1.9
1.5
—
—
—
0
0
33
192
1.78
2.37
4.3
9.1
23.99
24.67
mmol/l
0.73
33
187
414
3942
1.79
2.37
13.3
10.4
27.08
26.08
u/l
0.55
405
3802
7
17
4.17
2.37
1.0
1.4
—
—
—
0
0
58
396
1.53
2.27
2.0
1.8
—
—
—
0
0
5
9
5.60
2.22
1.0
1.3
—
—
—
0
0
28
161
1.79
2.11
1.1
1.0
—
—
—
0
0
75
549
1.44
2.10
2.1
2.0
13.56
13.55
umol/l
0.00
67
513
20
103
1.99
2.08
1.4
1.2
—
—
—
0
0
188
1598
1.31
2.03
3.0
2.5
141.57
122.49
ug/l
0.46
175
1475
34
210
1.67
2.01
1.5
1.3
—
—
—
0
0
14
64
2.23
1.96
1.6
2.5
14.52
15.83
%
—
6
25
395
3745
1.51
1.96
5.0
5.0
2.80
2.78
mmol/l
0.19
358
3447
56
393
1.49
1.94
1.9
1.8
—
—
—
0
0
16
78
2.09
1.93
1.1
1.4
—
—
—
0
0
196
1686
1.29
1.91
2.9
2.5
—
—
—
0
0
14
65
2.19
1.90
2.0
1.8
—
—
—
0
0
44
296
1.54
1.86
4.3
2.4
64.68
66.33
ml/min/173m2
0.14
25
120
88
677
1.37
1.86
4.6
3.6
290.42
214.62
ng/l
0.19
73
525
388
3674
1.46
1.85
4.5
4.5
4.69
4.70
mmol/l
0.02
349
3402
61
443
1.44
1.79
1.8
1.8
1.53
1.47
%
0.17
47
389
32
202
1.63
1.77
1.8
1.7
—
—
—
0
0
19
104
1.86
1.70
1.5
1.4
296.42
304.59
ug/g
0.06
12
60
21
119
1.80
1.69
1.6
1.4
—
—
—
0
0
17
90
1.92
1.67
1.8
1.7
—
—
—
0
0
25
150
1.71
1.67
1.3
2.1
1.42
1.49
g/l
0.18
18
130
10
41
2.47
1.65
2.1
1.9
12.15
17.08
ug/l
—
10
41
87
681
1.35
1.65
1.8
1.7
1120.63
1206.67
nmol/l
0.38
66
507
18
98
1.87
1.64
1.8
1.9
1215.86
1920.09
u/l
—
7
35
7
26
2.72
1.58
2.4
2.8
—
—
—
0
0
0
43
0.00
1.53
0.0
1.1
—
—
—
0
0
0
45
0.00
1.50
0.0
1.1
—
—
—
0
0
9
38
2.40
1.46
2.4
1.7
—
—
—
0
0
422
4095
1.67
1.46
27.5
20.2
252.06
249.77
e9/l
0.28
413
3993
95
767
1.30
1.46
1.8
1.7
450.95
438.17
pmol/l
0.14
77
635
11
52
2.14
1.45
1.5
1.3
0.60
0.55
nmol/l
0.14
11
46
204
1809
1.24
1.42
5.1
4.7
0.00
0.00
estimate
-0.00
43
337
422
4098
1.66
1.41
27.4
20.2
4.46
4.50
e12/l
0.81
412
3988
14
74
1.92
1.40
1.2
1.4
—
—
—
0
0
14
74
1.92
1.40
1.2
1.4
—
—
—
0
0
16
89
1.83
1.39
1.2
1.2
—
—
—
0
0
38
266
1.47
1.38
4.3
3.1
72.16
75.12
ng/l
0.16
33
237
202
1797
1.23
1.35
3.9
3.5
0.00
0.00
estimate
0.50
47
362
9
42
2.17
1.34
1.6
1.6
—
—
—
0
0
9
42
2.17
1.34
1.6
1.6
—
—
—
0
0
205
1829
1.23
1.32
3.9
3.5
0.00
0.01
estimate
0.50
44
326
106
880
1.27
1.31
2.5
2.3
—
—
—
0
0
5
18
2.80
1.29
3.0
3.3
69.40
90.17
nmol/l
—
5
18
8
35
2.31
1.27
1.3
1.2
—
—
—
0
0
19
115
1.68
1.27
1.5
1.3
—
1.22
—
0
5
16
92
1.77
1.26
1.9
1.7
—
—
—
0
0
421
4096
1.59
1.26
27.4
20.3
40.32
40.32
%
0.01
404
3848
11
56
1.99
1.23
1.2
1.1
—
—
—
0
0
5
19
2.65
1.22
1.2
2.1
110.80
101.21
%
—
5
19
421
4101
1.56
1.18
27.7
20.3
134.18
135.59
g/l
1.27
416
4037
8
39
2.07
1.16
2.0
1.7
—
—
—
0
0
0
35
0.00
1.15
0.0
1.0
—
—
—
0
0
69
553
1.29
1.13
1.5
1.4
—
—
—
0
0
8
40
2.02
1.12
1.3
1.2
—
—
—
0
0
7
31
2.28
1.11
2.7
2.3
—
—
—
0
0
340
3223
1.24
1.10
23.0
16.2
14.63
14.96
%
0.62
329
3169
8
41
1.97
1.09
1.6
2.0
—
—
—
0
0
12
67
1.81
1.05
3.5
3.6
55.00
59.13
%
0.35
12
67
380
3656
1.28
1.02
4.5
4.4
1.46
1.48
mmol/l
0.51
337
3367
10
54
1.87
0.97
1.8
1.5
—
—
—
0
0
159
1420
1.19
0.95
3.7
3.6
28.30
61.21
ng/l
0.70
102
980
368
3536
1.24
0.94
4.1
4.0
1.29
1.29
mmol/l
0.02
327
3245
6
27
2.24
0.94
1.8
1.7
—
—
—
0
0
49
386
1.30
0.93
3.4
4.4
12.65
25.03
ug/l
0.44
39
323
35
264
1.35
0.89
1.6
2.1
12.30
13.20
nmol/l
0.25
29
236
78
655
1.23
0.89
1.4
1.3
19.86
37.20
iu/ml
2.02
16
223
11
64
1.74
0.87
1.5
1.8
—
—
—
0
0
11
64
1.74
0.87
1.5
1.8
—
—
—
0
0
100
865
1.20
0.85
1.6
1.5
18.37
21.36
nmol/l
1.50
84
730
41
320
1.31
0.84
3.9
3.4
1.78
2.16
mmol/l
0.37
33
254
8
46
1.75
0.83
1.6
1.9
—
—
—
0
0
116
1022
1.18
0.81
1.5
1.7
1.32
1.36
mmol/l
0.21
92
871
41
323
1.30
0.80
3.8
3.4
5.86
5.82
kpa
0.09
36
313
5
99
0.50
0.78
1.2
1.4
541.00
475.91
mg/l
—
5
92
9
54
1.68
0.75
1.3
1.3
—
—
—
0
0
109
962
1.18
0.74
4.5
3.8
0.00
0.00
estimate
-0.00
43
330
10
60
1.68
0.72
1.9
1.6
—
—
—
0
0
17
118
1.46
0.70
2.2
1.6
—
—
—
0
0
11
69
1.61
0.69
1.8
1.5
—
—
—
0
0
7
118
0.59
0.68
1.0
1.8
—
—
—
0
0
19
136
1.41
0.68
1.5
1.8
—
—
—
0
0
5
28
1.79
0.66
2.6
1.6
—
—
—
0
0
35
278
1.28
0.66
3.3
2.8
4.46
4.43
kpa
0.03
30
268
13
87
1.51
0.64
1.8
1.7
—
—
—
0
0
357
3457
1.17
0.63
5.7
5.7
39.12
39.92
mmol/mol
1.03
328
3224
17
122
1.41
0.61
1.6
1.8
—
163.33
—
0
6
8
51
1.58
0.60
2.1
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
1.10
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
6
36
1.68
0.57
1.3
1.1
—
94.40
—
0
5
5
89
0.56
0.56
1.0
1.4
3.32
3.84
mmol/l
—
5
81
10
65
1.55
0.56
3.2
3.2
3.88
4.87
e9/l
—
10
65
6
37
1.63
0.55
3.0
2.0
—
—
—
0
0
6
39
1.55
0.53
2.0
1.8
—
—
—
0
0
6
39
1.55
0.53
2.0
1.8
—
—
—
0
0
6
39
1.55
0.53
2.0
1.8
—
—
—
0
0
10
67
1.50
0.50
2.4
1.5
—
—
—
0
0
7
45
1.56
0.49
1.7
1.5
—
—
—
0
0
119
1092
1.12
0.48
2.5
2.1
191.94
249.43
u/l
0.37
109
1023
18
137
1.33
0.48
2.4
2.0
—
—
—
0
0
10
68
1.48
0.47
1.5
1.2
—
—
—
0
0
17
129
1.33
0.46
1.6
2.3
—
—
—
0
0
13
94
1.39
0.46
1.3
1.4
—
—
—
0
0
14
103
1.37
0.45
1.6
1.4
88.38
246.96
miu/ml
—
8
54
70
624
1.14
0.44
1.4
1.3
3.61
12.28
u/ml
1.62
24
246
6
92
0.65
0.42
1.8
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
149
1398
1.10
0.40
4.0
3.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
16
127
1.27
0.34
1.5
2.9
—
—
—
0
0
17
137
1.25
0.32
2.6
1.8
—
—
—
0
0
46
411
1.13
0.30
4.1
7.4
0.13
1.33
mmol/l
1.33
40
343
50
450
1.13
0.30
8.1
7.1
—
—
—
0
0
7
57
1.23
0.29
1.3
1.1
—
—
—
0
0
18
149
1.22
0.28
2.8
2.0
—
—
—
0
0
107
1131
0.93
0.25
4.2
3.8
5.36
8.71
mg/mmol
0.73
69
692
6
82
0.73
0.24
1.0
1.5
0.88
0.85
nmol/l
—
6
69
0
11
0.00
0.21
0.0
1.0
—
1453.55
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
20
173
1.16
0.21
1.8
1.9
—
—
—
0
0
29
324
0.89
0.21
1.7
1.7
—
—
—
0
0
11
89
1.24
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
11
91
1.21
0.17
1.2
1.6
—
—
—
0
0
7
62
1.13
0.17
1.3
1.5
—
—
—
0
0
7
62
1.13
0.17
1.3
1.5
—
—
—
0
0
7
62
1.13
0.17
1.3
1.5
—
—
—
0
0
24
215
1.12
0.17
4.4
3.4
3.33
1.89
mmol/l
1.06
16
165
8
68
1.18
0.16
1.5
1.5
—
—
—
0
0
8
68
1.18
0.16
1.8
1.8
—
—
—
0
0
8
99
0.80
0.13
1.6
1.3
—
—
—
0
0
109
1056
1.04
0.12
2.9
3.1
1783.10
1044.08
ng/l
0.83
89
897
63
659
0.95
0.12
2.6
2.9
0.65
0.72
ug/l
0.60
37
432
13
114
1.14
0.12
2.7
1.5
0.23
0.23
g/l
0.05
13
109
83
801
1.04
0.11
4.2
3.7
1.02
1.02
kg/l
—
10
106
110
1132
0.96
0.11
4.3
4.7
1.71
2.46
ug/l
1.12
97
1024
49
466
1.06
0.11
4.1
4.6
30.23
31.81
%
0.44
31
314
13
115
1.13
0.10
1.8
1.5
—
—
—
0
0
88
908
0.96
0.10
3.8
4.1
23.10
21.42
%
0.58
47
415
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
62
0.80
0.08
1.6
1.3
—
110.64
—
0
11
5
65
0.77
0.08
1.0
1.2
19.98
16.04
u/l
—
5
55
116
1135
1.03
0.08
3.3
3.1
7.84
7.44
mmol/l
0.39
99
948
34
357
0.95
0.07
2.3
2.0
—
—
—
0
0
10
112
0.89
0.07
1.4
1.5
—
—
—
0
0
9
102
0.88
0.06
1.0
1.2
—
—
—
0
0
31
324
0.95
0.05
2.0
1.8
—
—
—
0
0
13
121
1.08
0.03
2.6
1.5
1.17
1.19
g/l
0.10
13
116
231
2299
1.01
0.02
3.4
3.0
—
—
—
0
0
11
106
1.04
0.00
1.5
1.7
36.18
39.77
nmol/l
0.40
11
100
24
238
1.01
0.00
1.3
1.3
—
51.11
—
0
20
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
57
0.88
0.00
1.6
1.3
5.52
7.23
mmol/l
—
5
47
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
65.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.1
—
16.07
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
70
1.00
-0.00
1.4
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_TONSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.132 [0.94, 1.37] | 0.203 |
| Birth year | 0.995 [0.99, 1.0] | 0.236 |
During the follow-up period (1.1.1998 — 31.12.2019), 175 out of 1274 females with CD2_BENIGN_TONSIL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.917 [1.5, 2.46] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 943 males with CD2_BENIGN_TONSIL died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_TONSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.13% | 0.355% |
| 5 | 0.709% | 2.208% |
| 10 | 1.835% | 5.227% |
| 15 | 3.23% | 10.463% |
| 20 | 5.62% | 18.211% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_TONSIL – Benign neoplasm: Tonsil
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data