≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Benign neoplasm: Tonsil

DOID Endpoint Browser PheWeb

CD2_BENIGN_TONSIL

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D10.4&
  • Hospital discharge: ICD-9 — 2105
  • Hospital discharge: ICD-8 — 2105
  • Cause of death: ICD-10 — D10.4&
  • Cause of death: ICD-9 — 2105
  • Cause of death: ICD-8 — 2105

2 out of 7 registries used, show all original rules.

415

4. Check minimum number of events

None

415

5. Include endpoints

None

415

6. Filter based on genotype QC (FinnGen only)

415

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum tonsillae palatinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2787 1600 1173
Only index persons 2614 1535 1079
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.05 0.06 0.04
Median age at first event (years)
Whole population 56.41 55.74 57.29
Only index persons 55.84 55.41 56.47

-FinnGen-

Key figures

All Female Male
Number of individuals 415 245 170
Unadjusted period prevalence (%) 0.08 0.08 0.07
Median age at first event (years) 59.35 56.63 63.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
367
Matched controls
3668
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
+∞
323.0
353
*
EMA10
NOMESCO Finland
Biopsy of tonsil
420.5
70.1
68
*
EMB10
NOMESCO Finland
Tonsillectomy
11.8
41.0
79
83
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
157.6
40.7
42
*
C09.9
ICD-10 Finland
Malignant neoplasm: Tonsil, unspecified
198.9
35.4
36
*
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
90.5
30.3
33
*
ENA10
NOMESCO Finland
Biopsy of pharynx
62.2
29.7
34
6
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
24.0
24.8
35
16
JDB10
NOMESCO Finland
Percutaneous gastrostomy
28.1
23.1
31
12
130
Kela drug reimbursment
Malignant tumour
5.3
20.7
67
148
C09.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tonsil
199.8
18.7
19
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.7
18.6
56
113
UDQ12
NOMESCO Finland
Flexible laryngoscopy
6.1
18.6
52
96
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
42.2
16.5
20
5
WF002
NOMESCO Finland
Radical radiotherapy
5.7
16.0
47
92
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
15.6
109
458
J35.1
ICD-10 Finland
Hypertrophy of tonsils
14.3
13.9
23
17
8070/3-C09.0
ICD-O-3
Squamous cell carcinoma, NOS, of tonsillar fossa
+∞
13.6
13
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
17.5
13.1
20
12
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.2
11.8
46
122
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.2
11.7
36
75
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
11.6
167
1006
EMB00
NOMESCO Finland
Excision of lesion of tonsil or adenoids
123.7
11.5
12
*
R07.0
ICD-10 Finland
Pain in throat
4.5
11.5
41
100
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
20.8
11.2
16
8
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.2
10.7
137
774
UJC01
NOMESCO Finland
Scopy of lower throat
14.2
9.3
15
11
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.9
9.1
29
63
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.6
9.0
30
69
A04AA02
ATC
granisetron; systemic, transdermal
3.7
8.9
39
115
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.6
8.8
30
70
N02AA05
ATC
oxycodone; systemic
2.5
8.7
72
326
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
+∞
8.4
8
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
7.1
8.2
19
28
H02AB02
ATC
dexamethasone; systemic
2.9
8.2
50
188
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
8.0
120
710
R21
ICPC
Throat symptom/complaint
2.3
7.9
80
399
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
15.4
7.8
12
8
J39.2
ICD-10 Finland
Other diseases of pharynx
12.2
7.6
13
11
ZX095
NOMESCO Finland
Combined chemoradiotherapy
10.3
7.6
14
14
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.7
7.5
18
28
EHA10
NOMESCO Finland
Biopsy of palate
13.7
7.4
12
9
XX3DW
NOMESCO Finland
Time consuming IT work
2.7
7.4
50
201
21050
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Tonsil
+∞
7.3
7
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
8.2
7.2
15
19
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.9
6.7
42
159
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
12.6
6.6
11
9
WX110
NOMESCO Finland
Local anesthesy
1.8
6.5
251
2003
D10.5
ICD-10 Finland
Benign neoplasm: Other parts of oropharynx
71.0
6.4
7
*
N02BE01
ATC
paracetamol; systemic, rectal
2.1
6.4
315
2732
SXC03
NOMESCO Finland
Other oral or dental procedure
11.3
6.3
11
10
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
18.4
6.3
9
5
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
6.3
6
*
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
+∞
6.3
6
*
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
6.3
6
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
6.3
6
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
5.9
6.2
16
28
A07AA02
ATC
nystatin; oral
3.1
6.2
33
115
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.0
6.2
23
60

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
257
1405
3.18
28.78
2.5
2.1
—
—
—
0
0
98
316
3.75
26.14
1.7
1.4
—
—
—
0
0
25
37
7.13
16.32
1.2
1.1
—
—
—
0
0
120
563
2.59
15.93
4.5
3.2
0.8
0.8
mmol/l
0.82
112
532
185
1163
2.07
11.57
4.5
3.3
2.4
2.4
mmol/l
1.16
162
1022
239
1685
1.99
10.47
5.5
6.4
1.2
1.2
mmol/l
0.27
197
1423
331
2680
2.16
9.16
9.5
7.5
76.2
77.8
u/l
0.39
321
2512
265
2005
1.89
8.67
12.4
9.4
4.0
4.1
e9/l
0.41
232
1781
206
1448
1.84
8.45
5.1
4.5
35.9
35.6
g/l
0.38
200
1351
246
1827
1.85
8.44
7.1
6.2
10.2
11.2
umol/l
1.37
239
1735
169
1125
1.85
8.21
6.4
5.7
—
—
—
0
0
213
1551
1.77
7.45
4.8
5.5
1.2
1.2
mmol/l
0.13
199
1417
119
734
1.87
7.20
1.3
1.3
0.6
2.0
u/ml
1.63
29
208
209
1534
1.73
6.94
11.3
9.5
0.0
0.0
e9/l
0.45
174
1268
106
639
1.88
6.85
3.9
3.0
2.5
2.5
mmol/l
0.38
94
553
80
441
2.01
6.71
1.3
1.2
—
—
—
0
0
220
1653
1.70
6.59
7.8
6.0
27.0
28.1
%
0.68
208
1555
216
1616
1.70
6.57
7.8
6.1
9.0
8.6
%
0.64
206
1524
217
1632
1.69
6.42
7.5
5.8
57.7
57.0
%
0.31
207
1539
226
1721
1.69
6.35
7.5
5.8
0.6
0.6
e9/l
0.63
199
1504
231
1770
1.69
6.34
7.8
5.8
1.8
1.9
e9/l
0.92
206
1580
107
662
1.83
6.32
1.5
1.6
2.2
2.5
g/l
0.71
61
411
226
1732
1.67
6.11
7.7
5.8
0.0
0.0
e9/l
0.18
198
1515
213
1609
1.67
6.08
7.7
5.9
2.6
2.8
%
0.44
202
1508
231
1782
1.67
6.07
7.7
6.0
0.2
0.2
e9/l
1.28
206
1589
206
1555
1.64
5.81
7.9
5.9
0.7
0.7
%
0.21
195
1457
307
2594
1.71
5.32
4.8
4.1
12.5
11.8
mm/h
0.37
286
2381
148
1045
1.65
5.32
4.4
3.7
7.4
7.4
ph
0.76
34
196
313
2671
1.70
5.09
5.1
3.9
14.6
14.8
pmol/l
0.44
293
2433
361
3214
1.95
5.04
6.0
4.7
2.0
2.3
mu/l
0.36
337
2944
389
3563
2.46
4.99
19.5
15.8
139.6
139.7
mmol/l
0.47
380
3469
132
919
1.64
4.96
3.4
3.0
0.3
0.4
e6/l
0.67
98
693
389
3572
2.42
4.80
19.8
15.9
4.0
4.0
mmol/l
1.09
380
3475
291
2460
1.61
4.67
4.4
3.8
—
—
—
0
0
47
245
2.04
4.57
1.3
1.5
—
—
—
0
0
127
902
1.59
4.31
3.4
2.9
—
—
—
0
0
7
6
11.84
4.29
1.1
2.0
—
—
—
0
0
159
1192
1.54
4.24
4.3
3.6
134.7
85.1
e6/l
0.27
113
843
138
1005
1.56
4.18
3.7
3.0
31.6
132.2
e6/l
0.86
105
775
70
432
1.75
4.07
5.8
4.9
1.0
1.0
mmol/l
0.05
62
403
125
895
1.57
4.07
3.2
2.5
6858.8
7447.4
umol/l
0.04
111
765
65
394
1.77
4.01
2.2
2.4
88.1
151.7
ug/g
1.81
44
310
40
211
1.99
3.78
1.3
1.3
—
—
—
0
0
65
403
1.73
3.71
1.2
1.3
—
—
—
0
0
45
252
1.88
3.59
1.2
1.2
—
—
—
0
0
176
1387
1.47
3.54
2.0
2.0
100.5
96.4
pmol/l
0.49
92
697
375
3461
1.87
3.53
19.1
13.7
20.1
22.5
mg/l
0.88
322
2743
30
146
2.14
3.51
1.2
1.2
—
—
—
0
0
25
113
2.29
3.49
1.1
1.2
—
—
—
0
0
119
876
1.50
3.33
8.4
6.8
—
—
—
0
0
367
3384
1.73
3.22
4.9
4.5
5.9
6.0
mmol/l
0.49
339
3101
35
187
1.95
3.21
1.3
1.2
—
—
—
0
0
95
672
1.54
3.19
3.1
2.5
513.9
567.3
mosm/kgh2o
1.50
79
563
74
494
1.61
3.19
1.3
1.2
—
—
—
0
0
135
1031
1.46
3.12
3.9
3.8
—
—
—
0
0
61
390
1.66
3.12
1.8
1.6
—
—
—
0
0
52
319
1.72
3.09
2.8
2.0
392.2
369.2
nmol/l
0.40
47
292
119
891
1.47
3.03
4.8
4.2
—
—
—
0
0
345
3151
1.56
2.93
18.4
14.3
39.9
40.0
%
0.13
239
2279
40
231
1.81
2.92
1.3
1.2
83.6
132.6
iu/ml
0.65
15
98
67
447
1.59
2.89
2.0
2.1
23.3
23.2
%
0.02
58
393
108
800
1.47
2.89
2.3
2.0
3.4
3.2
mg/l
0.16
91
692
48
294
1.72
2.88
6.8
4.5
1.0
0.8
%
0.21
20
96
17
71
2.45
2.84
1.7
3.2
5.1
5.1
kpa
0.08
17
71
17
71
2.45
2.84
1.7
3.2
8.4
8.7
kpa
0.26
17
71
96
699
1.49
2.79
2.7
2.4
6.0
6.1
e6/l
0.03
83
615
238
2039
1.39
2.77
4.3
4.5
6.4
6.7
mmol/l
2.36
231
1898
45
275
1.71
2.72
7.0
4.7
0.0
0.1
%
2.18
17
86
59
388
1.61
2.71
3.1
2.6
5.1
8.4
umol/l
2.79
52
346
66
449
1.56
2.63
1.4
1.6
—
—
—
0
0
390
3701
1.89
2.52
13.3
10.4
26.8
26.0
u/l
0.41
382
3572
32
181
1.83
2.52
4.1
9.2
23.9
24.6
mmol/l
0.82
32
170
30
167
1.86
2.48
2.5
2.5
—
—
—
0
0
30
168
1.85
2.44
1.1
1.1
—
88.5
—
0
6
98
736
1.43
2.41
1.7
1.7
0.8
1.2
mg/l
2.19
73
587
45
285
1.65
2.40
3.6
3.6
—
—
—
0
0
136
1085
1.38
2.36
2.5
2.4
54.2
57.4
u/l
0.65
125
1019
54
360
1.57
2.35
1.5
1.6
—
—
—
0
0
55
370
1.56
2.31
3.2
2.6
1.6
1.8
%
0.94
48
336
67
476
1.49
2.19
1.9
2.1
2.4
2.4
g/l
0.39
59
441
373
3521
1.59
2.15
5.0
5.0
2.8
2.8
mmol/l
0.48
337
3236
14
62
2.30
2.10
1.6
2.6
14.5
16.0
%
—
6
23
185
1572
1.32
2.06
4.5
4.0
—
—
—
0
0
84
632
1.41
2.04
4.7
3.6
310.2
194.7
ng/l
0.29
68
493
14
63
2.26
2.03
1.6
2.9
—
—
—
0
0
11
44
2.54
2.02
1.5
1.2
—
—
—
0
0
10
38
2.67
2.02
2.1
1.9
12.1
17.6
ug/l
—
10
38
15
70
2.19
2.00
1.1
1.7
—
—
—
0
0
366
3451
1.51
2.00
4.5
4.5
4.7
4.7
mmol/l
0.06
328
3191
17
84
2.07
1.98
1.7
3.1
7.4
7.4
ph
0.26
17
71
60
426
1.48
1.98
1.5
1.4
—
—
—
0
0
71
521
1.44
1.98
1.9
2.1
13.7
13.6
umol/l
0.04
63
481
102
798
1.37
1.96
6.8
4.7
—
—
—
0
0
177
1504
1.31
1.94
2.9
2.5
141.8
123.2
ug/l
0.41
164
1386
10
39
2.60
1.93
1.5
1.3
—
—
—
0
0
24
136
1.81
1.91
1.3
2.2
1.4
1.5
g/l
0.50
17
117
165
1392
1.31
1.90
6.6
7.9
1.1
1.2
inr
0.41
58
394
398
3838
1.90
1.87
27.5
20.3
253.2
249.4
e9/l
0.52
389
3745
265
2385
1.31
1.86
5.1
4.2
—
—
—
0
0
14
66
2.16
1.84
1.6
2.7
—
—
—
0
0
398
3840
1.89
1.83
27.4
20.2
91.2
91.1
fl
0.12
393
3784
398
3840
1.89
1.83
27.4
20.2
30.3
30.3
pg
0.24
393
3783
5
12
4.20
1.83
3.2
4.6
59.1
51.7
%
—
5
12
398
3841
1.88
1.82
27.5
20.3
6.7
6.6
e9/l
0.10
389
3739
398
3841
1.88
1.82
27.4
20.3
4.5
4.5
e12/l
0.73
388
3740
8
29
2.79
1.80
1.3
1.9
1.1
0.8
e9/l
—
8
13
125
1022
1.32
1.79
3.0
3.0
—
—
—
0
0
71
531
1.41
1.79
1.7
1.8
—
—
—
0
0
132
1088
1.31
1.78
2.8
2.3
—
—
—
0
0
84
647
1.37
1.78
1.9
1.7
1086.6
1212.8
nmol/l
0.63
64
484
41
275
1.54
1.77
1.6
1.4
—
—
—
0
0
11
48
2.33
1.72
1.5
1.2
0.6
0.5
nmol/l
0.15
11
43
24
143
1.72
1.65
2.8
3.0
24.6
24.4
mmol/l
0.19
19
133
39
264
1.53
1.63
6.6
4.5
0.5
0.5
%
0.13
11
70
21
345
0.59
1.59
1.3
1.4
—
—
—
0
0
312
2897
1.31
1.59
23.5
16.6
14.0
13.7
%
1.74
301
2846
20
115
1.78
1.55
1.6
1.6
—
—
—
0
0
397
3844
1.76
1.55
27.7
20.4
134.1
135.5
g/l
1.17
392
3786
17
93
1.86
1.54
1.1
1.3
—
—
—
0
0
18
101
1.82
1.51
1.3
1.4
305.2
301.5
ug/g
0.02
11
58
378
3623
1.49
1.51
16.0
12.8
—
—
—
0
0
38
261
1.50
1.50
7.8
4.7
0.0
0.0
%
0.80
13
75
192
1692
1.25
1.46
3.6
3.5
0.0
0.0
estimate
0.00
43
320
7
28
2.52
1.46
1.1
1.1
—
—
—
0
0
10
46
2.20
1.41
1.3
1.2
—
—
—
0
0
193
1711
1.24
1.37
4.8
4.7
0.0
0.0
estimate
0.00
43
321
44
318
1.43
1.36
1.4
1.4
—
—
—
0
0
13
68
1.94
1.35
3.2
1.9
—
—
—
0
0
61
469
1.35
1.32
1.6
1.3
404.4
497.2
titre
0.27
18
116
194
1730
1.23
1.28
3.7
3.5
0.0
0.0
estimate
0.50
44
310
19
115
1.68
1.27
1.2
2.0
26.1
22.0
s
0.33
19
103
12
63
1.93
1.24
3.5
3.7
55.0
59.4
%
0.37
12
63
37
264
1.44
1.24
4.9
7.9
—
—
—
0
0
8
37
2.18
1.22
1.6
1.6
—
—
—
0
0
8
37
2.18
1.22
1.6
1.6
—
—
—
0
0
8
37
2.18
1.22
1.6
1.6
—
—
—
0
0
8
37
2.18
1.22
1.6
1.6
—
—
—
0
0
15
86
1.77
1.20
1.6
1.9
1418.5
2271.8
u/l
—
6
29
348
3317
1.30
1.19
4.1
4.0
1.3
1.3
mmol/l
0.03
309
3042
88
724
1.27
1.18
1.8
1.7
456.9
437.0
pmol/l
0.22
72
599
35
250
1.44
1.17
2.9
3.1
75.3
74.9
ng/l
0.02
30
220
21
135
1.59
1.13
1.4
1.3
—
2.2
—
0
9
48
365
1.36
1.13
3.5
4.4
13.0
19.2
ug/l
0.21
38
307
55
428
1.33
1.12
14.1
19.8
1.1
1.3
inr
—
7
60
358
3433
1.31
1.11
4.5
4.5
1.5
1.5
mmol/l
0.77
316
3157
11
59
1.89
1.08
1.1
1.1
—
—
—
0
0
11
59
1.89
1.08
1.1
1.1
—
—
—
0
0
75
613
1.27
1.07
1.4
1.3
20.4
38.2
iu/ml
1.91
15
207
42
318
1.36
1.03
2.7
4.1
—
—
—
0
0
7
35
2.02
1.00
2.1
2.7
—
—
—
0
0
9
49
1.85
0.99
1.2
1.2
—
—
—
0
0
5
23
2.19
0.98
1.0
1.3
9.0
11.1
%
—
5
23
7
36
1.96
0.97
1.0
1.1
—
0.2
—
0
5
13
77
1.71
0.96
1.5
1.7
—
—
—
0
0
6
117
0.51
0.95
6.0
9.0
—
—
—
0
0
96
819
1.22
0.95
1.5
1.5
18.4
21.3
nmol/l
1.44
80
690
104
895
1.22
0.94
1.5
1.4
—
—
—
0
0
150
1337
1.19
0.94
3.7
3.6
29.9
63.7
ng/l
0.67
94
923
91
773
1.23
0.94
3.4
3.6
—
—
—
0
0
30
222
1.38
0.86
2.8
2.7
—
—
—
0
0
8
44
1.83
0.86
1.6
1.2
—
—
—
0
0
20
137
1.48
0.85
2.8
1.7
—
—
—
0
0
60
492
1.26
0.85
1.8
1.8
—
—
—
0
0
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
104
912
1.19
0.77
4.0
3.8
0.0
0.0
estimate
0.00
43
313
0
27
0.00
0.77
0.0
1.2
—
65.3
—
0
8
31
236
1.34
0.76
2.8
2.3
—
—
—
0
0
32
245
1.33
0.76
1.5
1.7
—
—
—
0
0
38
299
1.30
0.75
2.9
3.0
2.1
2.2
mmol/l
0.12
29
231
5
24
2.10
0.74
1.0
1.2
—
—
—
0
0
108
957
1.17
0.71
1.5
1.7
1.3
1.4
mmol/l
0.17
86
813
38
302
1.28
0.71
2.8
3.0
5.9
5.8
kpa
0.28
33
292
7
41
1.72
0.70
2.0
1.8
—
—
—
0
0
31
240
1.32
0.70
1.6
2.1
12.9
13.4
nmol/l
0.11
24
214
33
258
1.30
0.69
3.2
2.7
59.1
73.6
e9/l
1.09
23
198
10
61
1.66
0.69
3.2
3.3
3.9
4.8
e9/l
—
10
61
5
27
1.86
0.68
3.6
2.0
—
774.0
—
0
11
5
27
1.86
0.68
2.2
2.8
—
—
—
0
0
5
28
1.80
0.66
3.4
1.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
1.1
—
0
10
8
50
1.61
0.61
1.6
2.5
—
—
—
0
0
10
64
1.58
0.59
1.6
2.3
8.2
8.0
kpa
—
10
56
6
35
1.72
0.58
2.3
2.4
—
—
—
0
0
14
98
1.44
0.57
2.3
3.1
—
—
—
0
0
6
36
1.68
0.57
3.0
2.0
—
—
—
0
0
32
258
1.26
0.56
2.2
2.4
4.2
4.4
kpa
0.54
27
249
16
116
1.39
0.55
1.8
3.4
0.1
0.2
g/l
—
5
47
12
82
1.48
0.55
4.9
4.5
—
—
—
0
0
67
585
1.17
0.54
1.4
1.3
3.6
11.5
u/ml
1.46
24
235
9
64
1.42
0.52
1.4
2.1
—
—
—
0
0
13
93
1.41
0.48
1.6
1.4
94.9
238.2
miu/ml
—
7
49
14
102
1.39
0.48
1.2
1.2
—
—
—
0
0
112
1026
1.13
0.47
2.5
2.1
188.6
190.2
u/l
0.01
102
961
7
48
1.47
0.47
1.4
1.3
—
—
—
0
0
7
48
1.47
0.47
1.3
1.6
—
—
—
0
0
13
176
0.73
0.47
1.5
1.8
—
—
—
0
0
7
49
1.44
0.46
1.1
1.6
—
—
—
0
0
5
84
0.59
0.46
1.0
1.2
1.2
14.7
e6/l
—
5
68
5
84
0.59
0.46
1.2
1.3
20.2
1400.4
e6/l
—
5
71
21
165
1.29
0.46
3.6
3.3
—
—
—
0
0
5
32
1.57
0.42
1.6
2.7
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
1.3
—
0
11
334
3259
1.13
0.41
5.8
5.8
39.3
39.9
mmol/mol
0.74
307
3043
0
15
0.00
0.41
0.0
1.5
—
118729.7
—
0
9
44
381
1.17
0.41
4.0
7.6
0.0
1.3
mmol/l
1.41
38
314
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
27
224
1.22
0.39
1.4
2.6
4.7
4.0
e9/l
0.75
22
177
9
66
1.37
0.38
1.2
1.4
—
—
—
0
0
5
37
1.36
0.37
1.0
1.4
—
—
—
0
0
9
71
1.27
0.36
1.3
2.0
—
—
—
0
0
6
41
1.47
0.36
4.0
1.8
35.2
33.0
pg
—
6
41
17
135
1.27
0.36
2.6
2.8
—
—
—
0
0
6
42
1.43
0.35
3.2
3.7
—
—
—
0
0
6
44
1.37
0.34
2.5
1.4
—
—
—
0
0
19
154
1.24
0.34
1.1
1.1
—
—
—
0
0
6
45
1.34
0.34
1.3
1.5
—
—
—
0
0
6
45
1.34
0.34
1.3
1.5
—
—
—
0
0
7
52
1.35
0.31
1.0
1.1
—
—
—
0
0
7
52
1.35
0.31
2.0
3.0
—
—
—
0
0
10
131
0.76
0.31
4.2
5.0
—
—
—
0
0
11
84
1.32
0.30
1.1
1.4
—
—
—
0
0
7
56
1.25
0.29
2.1
1.5
—
—
—
0
0
57
620
0.91
0.25
2.5
3.0
0.7
0.7
ug/l
0.52
34
411
41
369
1.12
0.25
1.6
1.7
—
—
—
0
0
7
92
0.76
0.22
1.6
1.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
19
220
0.86
0.22
2.7
4.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
1453.5
—
0
11
0
11
0.00
0.21
0.0
1.1
—
0.8
—
0
6
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
111
1060
1.06
0.20
3.3
3.1
7.9
7.5
mmol/l
0.46
92
880
12
99
1.22
0.20
1.1
1.4
—
—
—
0
0
100
953
1.06
0.19
3.4
3.1
—
—
—
0
0
6
53
1.13
0.18
2.3
1.4
—
—
—
0
0
297
2924
1.06
0.17
23.4
17.7
331.2
332.3
g/l
1.13
292
2910
8
68
1.18
0.16
1.0
1.2
—
—
—
0
0
8
68
1.18
0.16
1.0
1.7
—
—
—
0
0
19
212
0.89
0.14
1.4
1.4
—
—
—
0
0
104
1004
1.05
0.13
3.1
3.2
48.6
319.2
mg/l
1.31
67
629
79
757
1.05
0.13
3.5
3.7
1.0
1.0
kg/l
—
10
102
11
94
1.17
0.13
3.3
4.1
—
—
—
0
0
103
1062
0.96
0.11
4.5
4.0
5.4
8.0
mg/mmol
0.54
65
649
12
105
1.15
0.11
1.1
1.4
—
—
—
0
0
28
260
1.08
0.11
1.6
1.4
—
—
—
0
0
102
1050
0.96
0.10
4.1
4.8
1.7
2.5
ug/l
1.07
89
951
12
106
1.14
0.10
1.1
1.4
—
—
—
0
0
12
106
1.14
0.10
1.1
1.4
—
—
—
0
0
12
106
1.14
0.10
1.1
1.4
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
1.0
1.1
20.0
16.1
u/l
—
5
52
15
164
0.91
0.08
4.6
2.9
—
—
—
0
0
6
75
0.80
0.07
1.0
1.5
0.9
0.9
nmol/l
—
6
64
24
227
1.06
0.06
1.3
1.3
—
38.4
—
0
16
12
131
0.91
0.05
1.0
1.1
—
—
—
0
0
16
170
0.94
0.04
5.1
8.5
—
—
—
0
0
28
271
1.04
0.02
3.5
3.3
—
—
—
0
0
129
1282
1.01
0.01
2.8
2.8
—
—
—
0
0
11
109
1.01
0.00
3.0
1.6
0.2
0.2
g/l
0.15
11
104
10
95
1.05
0.00
1.2
1.1
—
—
—
0
0
11
115
0.96
0.00
2.9
1.5
1.2
1.2
g/l
0.04
11
110
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
6.5
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
7
69
1.01
0.00
3.0
3.2
66.0
26.6
u/ml
—
7
69
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
3084.3
—
0
6
0
6
0.00
0.00
0.0
1.5
—
13.8
—
0
6
0
6
0.00
0.00
0.0
1.5
—
37.5
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
1.7
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
25.3
—
0
8
11
110
1.00
0.00
4.0
2.0
708.8
279.5
ug/l
0.60
11
103
0
9
0.00
0.00
0.0
3.0
—
50.0
—
0
9
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_TONSIL and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_TONSIL 1.132 [0.94, 1.37] 0.203
Birth year 0.995 [0.99, 1.0] 0.236

During the follow-up period (1.1.1998 — 31.12.2019), 175 out of 1274 females with CD2_BENIGN_TONSIL died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_TONSIL 1.917 [1.5, 2.46] < 0.001
Birth year 0.989 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 943 males with CD2_BENIGN_TONSIL died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_TONSIL.

N-year risk Females Males
1 0.13% 0.355%
5 0.709% 2.208%
10 1.835% 5.227%
15 3.23% 10.463%
20 5.62% 18.211%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_TONSIL – Benign neoplasm: Tonsil

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data