≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Placental disorders

DOID EFO Endpoint Browser PheWeb

O15_PLAC_DISORD

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O43
  • Hospital discharge: ICD-9 — 6560|6567
  • Cause of death: ICD-10 — O43
  • Cause of death: ICD-9 — 6560|6567

2 out of 7 registries used, show all original rules.

376

4. Check minimum number of events

None

376

5. Include endpoints

None

376

6. Filter based on genotype QC (FinnGen only)

359

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O30-O48
Name in latin
Morbositates placentae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2428 2428 -
Only index persons 2399 2399 -
Unadjusted period prevalence (%)
Whole population 0.07 0.07 -
Only index persons 0.09 0.09 -
Median age at first event (years)
Whole population - 31.60 -
Only index persons - 31.60 -

-FinnGen-

Key figures

All Female Male
Number of individuals 359 359 -
Unadjusted period prevalence (%) 0.13 0.13 -
Median age at first event (years) 31.99 31.99 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
376
Matched controls
3760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
23.8
209.1
189
153
O43.8
ICD-10 Finland
Other placental disorders
+∞
140.7
126
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
45.3
134.4
82
23
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
1391.0
110.3
102
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
15.9
103.8
100
84
O60
ICD-10 Finland
Preterm labour and delivery
35.2
102.9
67
23
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
13.7
91.4
96
92
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
9.4
89.0
135
212
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
9.0
86.0
135
220
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
977.6
82.8
78
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
7.1
81.6
202
526
O43.0
ICD-10 Finland
Placental transfusion syndromes
+∞
67.8
63
*
O43.9
ICD-10 Finland
Placental disorder, unspecified
+∞
66.7
62
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
5.9
64.9
191
562
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
27.7
60.3
42
17
O32.1
ICD-10 Finland
Maternal care for breech presentation
571.5
51.7
50
*
O43.2
ICD-10 Finland
Morbidly adherent placenta
+∞
51.2
48
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
+∞
49.0
46
*
SPAT1379
SPAT
Health check-up of pregnant person
4.6
43.0
141
431
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
4.2
41.4
173
630
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
41.4
39
*
O30.0
ICD-10 Finland
Twin pregnancy
+∞
40.3
38
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.0
39.3
222
989
W84
ICPC
Pregnancy high risk
7.2
38.1
62
100
SPAT1380
SPAT
Postpartum check-up
4.4
36.9
121
365
WX320
NOMESCO Finland
Spinalanesthesy
4.4
36.3
120
364
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
33.9
32
*
W78
ICPC
Pregnancy
3.7
33.1
171
699
SPAT1197
SPAT
Extensive health check-up of expecting family
3.8
32.4
142
520
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.7
31.6
142
528
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
339.7
31.3
31
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.9
30.9
118
392
6567A
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Other placental conditions[CONDITIO PLACENTAE ALIA, RASKAUDEN AIKANA]
+∞
30.6
29
*
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
4.0
29.4
106
337
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.8
26.6
68
166
ZXD05
NOMESCO Finland
Urgent procedure
3.2
26.4
159
696
MAA00
NOMESCO Finland
Amniocentesis
31.0
25.9
34
12
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
7.2
25.6
40
61
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
25.3
24
*
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
25.3
24
*
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
+∞
25.3
24
*
W92
ICPC
Compl labour/ delivery livebirth
9.8
25.1
30
33
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.2
24.3
76
216
O72.0
ICD-10 Finland
Third-stage haemorrhage
7.2
24.3
38
58
O48
ICD-10 Finland
Prolonged pregnancy
+∞
24.2
23
*
O41.0
ICD-10 Finland
Oligohydramnios
+∞
22.1
21
*
6567B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Other placental conditions[CONDITIO PLACENTAE ALIA, SYNNYTYKSEN AIKANA]
+∞
22.1
21
*
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
+∞
22.1
21
*
OAA11, ,
SPAT
4.4
21.6
61
160
O43.1
ICD-10 Finland
Malformation of placenta
+∞
21.0
20
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
221.8
20.8
21
*
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
24.0
20.7
29
13
SPAT1196
SPAT
Monitoring of normal pregnancy
3.8
20.5
73
226
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
3.8
20.0
68
204
TPH07
NOMESCO Finland
Cathetrisation of artery
5.4
19.5
41
84
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
8.4
19.4
26
33
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
5.5
18.3
37
73
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.7
18.1
65
202
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
7.4
18.1
27
39
8811
FHL
Cesarean section
4.9
17.8
42
95
MA3AE
NOMESCO Finland
Combined first trimester screening
3.6
17.4
64
202
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.4
17.2
73
252
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
66.5
16.9
19
*
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
16.8
16
*
O40
ICD-10 Finland
Polyhydramnios
+∞
16.8
16
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
5.3
16.5
35
72
SPAT1357
SPAT
Monitoring of problem during pregnancy
6.2
16.4
29
50
O02.1
ICD-10 Finland
Missed abortion
3.8
16.2
55
164
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
62.8
15.9
18
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
166.6
15.6
16
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.7
15.2
100
440
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.9
15.2
88
363
OAA12, ,
SPAT
4.4
14.9
40
100
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.8
14.9
88
366
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
14.7
14
*
6560B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Foetal-maternal haemorrhage[TRANSFUSIO FOETO-MATERNALIS, SYNNYTYKSEN AIKANA]
+∞
14.7
14
*
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
44.3
14.2
17
*
B01AB04
ATC
dalteparin; parenteral
5.5
14.1
28
54
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
13.6
13
*
O99.80
ICD-10 Finland
The fear of childbirth
3.7
13.5
46
137
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
23.5
13.0
18
8
O80.8
ICD-10 Finland
Other single spontaneous delivery
4.2
12.8
35
89
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.3
12.8
52
174
MBB10
NOMESCO Finland
Packing of delivered uterus
+∞
12.6
12
*
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
12.6
12
*
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.4
12.6
109
543
OAA10, ,
SPAT
3.8
12.2
39
111
SPAT1249
SPAT
Treatment-related counselling outside office
2.2
12.0
174
1070
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
3.6
11.9
41
123
MAB20
NOMESCO Finland
Failed external version
+∞
11.5
11
*
MA2BG
NOMESCO Finland
Fetal examination with high intensity magnet
+∞
11.5
11
*
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
11.5
11
*
WW500
NOMESCO Finland
Blood transfusion
5.6
11.0
21
39
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
5.4
10.9
22
43
O61.0
ICD-10 Finland
Failed medical induction of labour
13.4
10.8
18
14
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.1
10.7
181
1166
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.4
10.5
84
400
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
5.7
10.5
20
37
W90
ICPC
Uncompl labour/delivery livebirth
3.1
10.5
48
172
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
+∞
10.5
10
*
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
10.5
10
*
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
+∞
10.5
10
*
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
24.2
10.3
14
6
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.3
10.1
88
435
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
12.7
9.9
17
14
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
5.1
9.9
21
43
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
26.8
9.9
13
5
Z37.0
ICD-10 Finland
Single live birth
2.3
9.8
86
426
ZXE00
NOMESCO Finland
One hour or less
2.0
9.6
156
980
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
102.5
9.5
10
*
O47.9
ICD-10 Finland
False labour, unspecified
12.8
9.4
16
13
MAA54
NOMESCO Finland
Fetoscopy
+∞
9.4
9
*
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
9.4
9
*
O31.8
ICD-10 Finland
Other complications specific to multiple gestation
+∞
9.4
9
*
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
9.4
9
*
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
9.4
9
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
4.2
9.4
25
62
TLW12
NOMESCO Finland
Insertion of frozen embryo
4.2
9.4
25
62
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.2
9.1
38
129
Z31.5
ICD-10 Finland
Genetic counselling
3.0
9.0
42
152
W85
ICPC
Gestational diabetes
3.1
8.7
38
132
OAA41, ,
SPAT
4.2
8.7
23
57
MBA05
NOMESCO Finland
Curettage of uterus after abortion
10.4
8.6
16
16
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
4.6
8.5
20
45
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.1
8.4
18
37
B01AB05
ATC
enoxaparin; parenteral
2.1
8.4
95
519
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
8.8
8.4
17
20
O35.0
ICD-10 Finland
Maternal care for (suspected) central nervous system malformation in fetus
+∞
8.4
8
*
MAA06
NOMESCO Finland
Amnioreduction
+∞
8.4
8
*
O31.2
ICD-10 Finland
Continuing pregnancy after intrauterine death of one fetus or more
+∞
8.4
8
*
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
8.4
8
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
9.7
7.8
15
16
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.8
7.8
40
152
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
7.7
7.8
17
23
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
7.7
130
816
Z39.1
ICD-10 Finland
Care and examination of lactating mother
3.8
7.6
23
63
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
7.6
182
1274
J01DB01
ATC
cefalexin; oral
2.3
7.5
320
2696
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
81.6
7.4
8
*
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
81.6
7.4
8
*
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.6
7.4
45
187
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
7.1
7.4
17
25
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
7.3
7
*
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
+∞
7.3
7
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.8
7.2
37
141
TLW00
NOMESCO Finland
Insemination
3.9
7.2
21
56
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
6.2
7.2
18
30
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
4.3
7.1
18
43
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.8
7.0
37
143
XMA22
NOMESCO Finland
General examination of pregnant woman
2.7
7.0
39
155
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
3.1
6.9
29
99
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.3
6.9
26
83
OAA70, ,
SPAT
4.0
6.8
19
49
R2110
NOMESCO Finland
Giving the first information
2.6
6.8
40
164
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
5.7
6.7
18
33
Z30.2
ICD-10 Finland
Sterilization
2.3
6.7
55
263
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
12.5
6.6
11
9
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.5
133
879
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
14.6
6.4
10
7
O20.0
ICD-10 Finland
Threatened abortion
5.3
6.4
18
35
MAG00
NOMESCO Finland
Assisted breech delivery
27.2
6.3
8
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
163
764
3.00
23.46
1.8
1.6
—
—
—
0
0
70
212
3.83
20.31
1.7
1.4
—
—
—
0
0
76
252
3.53
19.22
1.6
1.2
—
—
—
0
0
171
892
2.68
19.21
2.0
1.6
—
—
—
0
0
65
202
3.68
18.07
1.6
1.3
—
—
—
0
0
65
204
3.64
17.80
1.6
1.3
—
—
—
0
0
97
412
2.83
15.87
2.2
1.8
—
—
—
0
0
111
590
2.25
10.81
2.2
2.0
—
—
—
0
0
14
6
24.15
10.31
4.2
1.5
—
—
—
0
0
203
1380
2.02
10.15
3.5
2.3
—
—
—
0
0
180
1187
1.99
9.67
2.2
2.0
—
—
—
0
0
167
1087
1.96
9.19
2.6
1.6
—
—
—
0
0
256
1930
2.02
9.11
4.6
3.4
—
886.00
—
0
22
26
70
3.92
8.77
3.2
1.9
6.47
4.36
umol/l
0.79
21
52
77
392
2.21
8.12
3.2
2.0
11350.90
2638.83
u/l
0.73
39
145
131
826
1.90
7.62
2.5
1.9
—
—
—
0
0
32
112
3.03
7.25
2.7
2.5
20.84
20.76
s
0.05
32
94
99
610
1.85
5.99
3.1
2.6
0.14
0.34
e6/l
1.29
66
441
98
618
1.79
5.44
3.2
2.5
—
—
—
0
0
101
646
1.77
5.34
3.5
2.9
—
—
—
0
0
249
2033
1.67
5.09
4.5
3.5
—
—
—
0
0
345
3115
2.30
4.93
10.8
9.2
17.40
18.14
mg/l
0.16
269
2301
76
461
1.81
4.75
2.4
2.2
7.18
10.81
e6/l
1.04
67
420
12
22
5.60
4.64
1.3
1.4
—
—
—
0
0
101
679
1.67
4.37
3.0
2.6
35.40
91.21
e6/l
0.65
66
508
19
67
2.93
4.29
1.2
1.5
—
—
—
0
0
126
913
1.57
3.97
3.7
3.0
112.90
41.63
e6/l
0.46
77
562
185
1462
1.52
3.91
4.5
4.0
0.00
0.00
estimate
0.50
41
281
107
749
1.60
3.89
2.7
2.0
—
—
—
0
0
122
884
1.56
3.82
1.4
1.3
1.35
1.45
u/ml
0.06
37
239
18
66
2.81
3.81
1.2
1.5
99.90
119.03
u/ml
—
5
14
32
157
2.13
3.68
7.9
7.3
-1.34
0.76
mmol/l
1.57
27
117
14
47
3.06
3.45
2.4
2.6
—
—
—
0
0
184
1482
1.47
3.39
3.5
2.9
0.00
0.00
estimate
-0.00
42
273
9
18
5.09
3.39
1.3
1.4
—
—
—
0
0
183
1473
1.47
3.38
3.4
2.9
0.00
0.00
estimate
-0.00
43
285
25
116
2.24
3.30
1.1
1.1
2.65
5.15
u/ml
—
6
26
170
1353
1.47
3.30
4.8
3.8
6.05
6.20
mmol/l
0.31
141
1241
16
60
2.74
3.27
1.2
1.4
27.37
32.83
nmol/l
0.43
16
53
43
247
1.84
3.20
3.0
2.8
—
—
—
0
0
17
67
2.61
3.17
8.8
10.1
—
—
—
0
0
16
62
2.65
3.08
2.1
1.8
—
—
—
0
0
13
45
2.96
3.05
1.2
1.3
—
—
—
0
0
74
504
1.58
2.97
3.1
2.3
51.84
91.20
ug/g
2.27
63
373
53
333
1.69
2.92
2.7
2.4
6.63
4.79
e6/l
0.26
27
164
24
117
2.12
2.84
6.0
8.8
—
—
—
0
0
67
453
1.58
2.77
2.5
3.7
—
—
—
0
0
64
430
1.59
2.71
2.6
2.4
509.70
520.63
mosm/kgh2o
0.14
54
377
21
101
2.14
2.58
2.1
2.4
—
—
—
0
0
164
1341
1.40
2.57
8.7
7.1
0.00
0.00
e9/l
0.66
133
1099
314
2890
1.52
2.40
13.6
10.8
13.91
14.15
%
0.46
309
2838
5
8
6.32
2.38
1.4
1.6
—
—
—
0
0
318
2938
1.53
2.35
8.8
8.8
139.14
139.50
mmol/l
2.33
308
2846
57
392
1.54
2.19
1.2
1.2
—
—
—
0
0
106
826
1.39
2.14
6.1
6.5
1.04
1.04
inr
0.07
48
297
19
96
2.03
2.09
2.5
2.1
4.71
4.62
iu/l
0.01
11
40
99
767
1.39
2.07
3.7
3.1
0.00
0.01
estimate
0.80
41
280
51
348
1.54
2.04
1.7
1.6
1144.11
1161.94
nmol/l
0.05
40
273
147
1216
1.34
2.03
3.3
2.7
6.71
5.80
ph
2.00
12
133
45
299
1.57
2.02
1.1
1.2
—
—
—
0
0
317
2950
1.48
2.02
8.8
8.8
3.86
3.89
mmol/l
1.18
307
2852
13
57
2.33
2.00
1.5
2.1
—
—
—
0
0
90
691
1.40
1.98
2.1
1.7
1.10
0.69
mg/l
0.84
74
498
9
35
2.61
1.81
1.2
1.1
—
—
—
0
0
82
630
1.39
1.79
3.4
2.9
1.01
1.01
kg/l
0.87
11
91
7
24
2.95
1.73
1.3
1.2
—
—
—
0
0
97
772
1.35
1.70
1.4
1.4
1.97
2.05
g/l
0.23
62
510
21
121
1.78
1.62
1.6
1.7
—
—
—
0
0
115
945
1.31
1.61
6.0
4.9
1.20
1.22
mmol/l
2.35
101
870
7
26
2.72
1.58
1.1
1.4
—
—
—
0
0
243
2203
1.29
1.57
3.7
3.4
8.25
8.67
mm/h
0.34
232
2075
116
961
1.30
1.52
4.8
4.2
37.31
37.18
g/l
0.09
111
905
6
21
2.89
1.51
1.0
1.0
—
—
—
0
0
73
566
1.36
1.51
1.2
1.2
1.62
15.08
u/ml
3.18
31
232
20
117
1.75
1.48
2.2
2.2
61.89
76.65
e9/l
1.26
15
85
25
156
1.65
1.48
1.2
1.4
3.15
2.84
ug/l
0.26
25
143
71
550
1.36
1.48
2.4
2.0
278.23
4061.95
umol/l
1.83
62
515
9
39
2.34
1.44
1.6
1.4
9.41
7.43
mmol/l
—
9
39
16
88
1.85
1.43
1.7
1.6
—
—
—
0
0
349
3357
1.55
1.40
10.8
8.5
—
—
—
0
0
40
550
0.69
1.37
1.2
1.3
—
—
—
0
0
204
1830
1.25
1.35
3.7
2.9
53.01
57.21
ug/l
0.33
189
1739
5
18
2.80
1.29
3.6
8.8
—
—
—
0
0
368
3604
1.99
1.28
17.4
14.0
254.14
273.33
e9/l
9.39
361
3535
24
155
1.59
1.26
3.9
3.0
1.21
1.23
mmol/l
1.06
17
136
126
1079
1.25
1.24
5.7
5.5
1.20
1.22
mmol/l
1.59
99
923
86
703
1.29
1.24
2.5
2.0
2.44
2.62
mg/l
0.55
72
594
16
93
1.75
1.23
1.0
1.0
1.72
1.68
u/ml
—
9
43
5
19
2.65
1.22
1.8
1.1
—
—
—
0
0
5
19
2.65
1.22
1.4
1.3
28.40
31.84
pg
—
5
19
15
86
1.78
1.21
8.0
9.2
95.45
94.62
%
0.47
15
86
10
50
2.03
1.17
1.2
3.2
1.05
1.42
mg/l
—
10
45
222
2033
1.22
1.14
6.8
6.2
70.25
71.66
u/l
0.26
210
1906
367
3598
1.84
1.11
17.4
13.8
38.67
39.92
%
5.92
355
3461
71
577
1.28
1.07
1.5
1.5
—
—
—
0
0
27
187
1.48
1.07
2.3
1.9
—
—
—
0
0
368
3610
1.91
1.05
17.5
13.9
7.03
6.59
e9/l
3.42
360
3528
368
3609
1.92
1.05
17.5
13.9
4.36
4.48
e12/l
7.08
361
3539
75
619
1.26
1.01
4.6
3.3
97.33
99.84
%
0.50
70
595
46
357
1.33
0.97
1.4
1.4
—
—
—
0
0
79
659
1.25
0.97
4.2
3.5
7.41
7.40
ph
0.52
15
117
10
55
1.84
0.93
1.1
1.1
—
—
—
0
0
6
29
2.09
0.89
3.7
1.9
31.75
9.91
u/ml
—
6
29
58
472
1.27
0.88
1.5
1.6
139130811.37
48131272.60
pmol/l
0.28
46
428
6
30
2.02
0.87
1.3
1.6
—
—
—
0
0
17
112
1.54
0.86
1.1
1.1
0.36
3.54
u/ml
—
5
53
8
44
1.84
0.86
1.7
3.1
7.42
7.43
ph
—
8
38
15
96
1.59
0.85
1.3
1.3
—
—
—
0
0
44
348
1.30
0.83
1.1
1.1
—
—
—
0
0
334
3233
1.30
0.83
10.1
9.5
64.34
65.79
umol/l
0.50
334
3233
8
46
1.75
0.83
1.0
1.5
—
—
—
0
0
147
1324
1.18
0.83
1.9
1.9
—
—
—
0
0
11
66
1.69
0.79
1.3
1.3
1.83
3.92
u/ml
—
6
24
0
25
0.00
0.79
0.0
1.6
—
0.94
—
0
25
14
90
1.58
0.79
13.1
8.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
290
3016
0.83
0.76
3.3
3.3
4.78
4.82
mmol/l
0.37
278
2910
13
83
1.59
0.76
10.5
4.9
—
—
—
0
0
25
185
1.38
0.74
6.4
6.6
105.68
104.84
mmol/l
0.47
25
185
19
134
1.44
0.73
2.4
3.7
—
—
—
0
0
10
60
1.68
0.72
4.8
3.3
3.22
4.32
e9/l
—
10
60
10
60
1.68
0.72
4.9
3.5
53.40
57.37
%
—
10
60
289
3003
0.84
0.72
3.2
3.3
1.50
1.55
mmol/l
1.58
277
2891
117
1302
0.85
0.72
2.1
2.1
—
—
—
0
0
293
3039
0.84
0.70
3.3
3.5
2.90
2.89
mmol/l
0.12
281
2919
13
85
1.55
0.70
1.0
1.0
4.61
5.27
u/ml
—
6
37
12
77
1.58
0.69
1.0
1.1
3.62
5.50
u/ml
—
6
26
30
232
1.32
0.68
1.4
1.2
—
—
—
0
0
5
28
1.80
0.66
1.4
1.4
91.12
91.94
%
—
5
28
277
2879
0.86
0.64
2.9
3.0
1.13
1.17
mmol/l
0.56
263
2759
6
103
0.58
0.63
1.5
1.2
—
—
—
0
0
73
635
1.19
0.61
1.9
1.4
—
—
—
0
0
185
1728
1.14
0.60
7.2
8.3
3.94
3.88
e9/l
0.16
166
1530
337
3288
1.24
0.60
9.1
7.7
24.24
23.60
u/l
0.23
324
3200
14
97
1.46
0.60
1.1
1.0
0.72
1.35
u/ml
—
5
40
7
115
0.60
0.58
1.1
1.8
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
1.65
—
0
23
98
879
1.16
0.57
2.6
2.4
—
—
—
0
0
219
2303
0.88
0.56
2.9
2.7
29.85
32.30
u/l
0.41
212
2221
104
940
1.15
0.55
1.9
1.8
97.83
100.28
pmol/l
0.18
58
545
58
502
1.18
0.53
4.6
4.0
13.15
10.61
mg/mmol
0.19
39
320
9
134
0.66
0.52
1.9
1.6
—
—
—
0
0
73
653
1.15
0.45
3.2
3.2
7.75
7.71
mmol/l
0.02
65
586
135
1257
1.12
0.44
4.4
5.0
9.72
9.12
umol/l
0.63
126
1178
5
31
1.62
0.43
1.4
1.4
1.28
1.67
mmol/l
—
5
31
6
95
0.63
0.42
1.0
1.2
—
—
—
0
0
14
105
1.35
0.41
1.1
1.0
2.80
4.93
u/ml
—
7
56
0
15
0.00
0.41
0.0
1.1
—
6.43
—
0
15
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
3.7
—
—
—
0
0
13
99
1.32
0.36
2.7
2.1
—
—
—
0
0
62
559
1.13
0.35
2.5
2.6
—
—
—
0
0
168
1599
1.09
0.34
6.1
5.7
0.19
0.17
e9/l
0.89
155
1454
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
54
486
1.13
0.32
4.1
3.5
79.38
349.60
mg/l
0.71
38
311
19
229
0.82
0.31
5.9
6.1
1.03
1.02
mmol/l
0.06
19
214
21
175
1.21
0.31
4.4
3.6
—
—
—
0
0
7
54
1.30
0.30
1.0
1.2
—
—
—
0
0
27
313
0.85
0.30
1.3
1.3
—
—
—
0
0
20
238
0.83
0.29
1.3
1.3
—
—
—
0
0
17
139
1.23
0.29
1.6
1.5
—
—
—
0
0
245
2518
0.92
0.29
4.2
4.0
36.76
37.22
mmol/mol
0.45
228
2408
161
1540
1.08
0.28
6.2
5.3
0.54
0.52
e9/l
0.54
147
1374
161
1542
1.08
0.27
6.2
5.3
0.04
0.04
e9/l
0.15
146
1374
8
64
1.26
0.27
1.3
1.0
—
—
—
0
0
151
1443
1.08
0.27
6.6
5.5
—
—
—
0
0
8
66
1.22
0.27
1.3
1.1
—
—
—
0
0
13
160
0.81
0.26
1.0
1.1
—
—
—
0
0
277
2710
1.08
0.26
5.2
4.2
14.10
14.20
pmol/l
0.34
265
2557
33
293
1.14
0.25
3.8
2.1
3.59
4.75
umol/l
1.87
26
243
20
232
0.85
0.23
3.1
4.1
0.83
1.14
%
—
6
62
16
135
1.19
0.22
2.6
4.0
5.72
5.76
kpa
0.06
16
130
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
66.32
—
0
6
0
11
0.00
0.21
0.0
1.5
—
0.08
—
0
11
0
11
0.00
0.21
0.0
2.6
—
11.95
—
0
11
0
11
0.00
0.21
0.0
1.6
—
8.45
—
0
11
0
10
0.00
0.21
0.0
3.1
—
112.20
—
0
5
78
734
1.08
0.21
5.2
6.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
28
312
0.89
0.20
1.5
1.3
—
—
—
0
0
44
405
1.10
0.19
1.3
1.2
150.63
149.23
iu/ml
0.01
13
174
34
309
1.11
0.19
1.5
1.3
—
—
—
0
0
303
2989
1.07
0.18
14.5
11.6
332.93
331.96
g/l
1.22
303
2963
7
62
1.13
0.17
9.4
4.9
—
—
—
0
0
7
62
1.13
0.17
1.0
1.3
—
—
—
0
0
5
67
0.74
0.17
1.0
1.5
—
—
—
0
0
55
516
1.08
0.16
1.3
1.3
970.00
587.05
titre
—
8
105
8
70
1.15
0.16
2.6
2.9
0.78
0.69
%
—
8
70
8
72
1.11
0.16
2.6
3.1
1.59
1.44
%
—
8
72
9
79
1.14
0.15
1.6
2.5
19.89
109.69
ng/l
—
9
71
9
80
1.13
0.15
1.1
1.2
—
—
—
0
0
147
1511
0.96
0.14
5.6
4.9
55.95
56.15
%
0.08
136
1423
165
1609
1.05
0.14
6.2
5.2
2.05
2.00
e9/l
0.35
157
1468
22
199
1.11
0.13
1.1
1.2
—
—
—
0
0
74
708
1.06
0.13
1.9
2.6
12.06
15.95
ng/l
0.62
22
289
9
108
0.83
0.13
1.3
2.5
—
7.40
—
0
11
20
221
0.90
0.13
3.1
4.2
0.17
0.08
%
—
6
51
9
110
0.81
0.13
1.6
2.5
4.75
5.09
kpa
—
9
104
309
3060
1.06
0.12
5.7
4.9
1.58
1.75
mu/l
2.93
296
2938
284
2871
0.96
0.11
3.1
3.3
5.40
5.56
mmol/l
3.35
272
2731
34
319
1.07
0.11
1.7
1.4
—
—
—
0
0
63
606
1.05
0.09
1.3
1.3
26.56
24.90
iu/ml
0.05
20
220
5
48
1.04
0.09
1.6
1.7
—
—
—
0
0
17
155
1.10
0.09
1.4
1.4
—
—
—
0
0
88
855
1.04
0.09
2.4
3.0
2.32
2.34
mmol/l
0.81
82
777
67
693
0.96
0.08
1.7
1.6
1.26
1.31
mmol/l
0.25
61
622
28
263
1.07
0.08
1.0
1.5
—
—
—
0
0
12
107
1.13
0.08
1.5
1.1
—
—
—
0
0
20
215
0.93
0.08
3.1
4.0
0.17
1.01
%
—
6
51
8
76
1.05
0.07
1.3
2.8
—
—
—
0
0
150
1524
0.97
0.07
5.9
5.1
30.09
29.98
%
0.05
139
1440
8
92
0.87
0.07
1.5
1.1
—
—
—
0
0
8
92
0.87
0.07
1.5
1.1
—
—
—
0
0
30
315
0.95
0.06
2.3
2.0
327.92
381.93
nmol/l
1.28
25
291
28
266
1.06
0.06
1.0
1.5
—
—
—
0
0
12
131
0.91
0.05
1.1
1.3
46.50
151.53
pmol/l
0.70
12
126
36
346
1.04
0.05
3.2
2.7
65.87
492.66
ng/l
0.83
15
158
11
100
1.10
0.05
1.3
1.1
—
—
—
0
0
26
248
1.05
0.05
1.0
1.5
—
—
—
0
0
172
1737
0.98
0.04
2.7
2.6
—
—
—
0
0
24
229
1.05
0.04
1.2
1.3
255.78
232.57
miu/ml
—
10
124
36
372
0.96
0.04
2.3
1.7
—
—
—
0
0
28
269
1.04
0.04
1.0
1.5
—
—
—
0
0
20
190
1.06
0.04
1.4
2.0
—
—
—
0
0
29
301
0.96
0.04
1.4
1.9
—
—
—
0
0
20
191
1.05
0.03
1.2
1.4
—
—
—
0
0
138
1393
0.99
0.03
5.9
5.2
0.69
0.68
%
0.11
123
1299
144
1452
0.99
0.02
5.9
5.1
2.86
2.66
%
0.46
132
1363
29
299
0.97
0.02
1.2
1.3
—
—
—
0
0
21
218
0.96
0.02
1.0
1.4
—
—
—
0
0
145
1458
0.99
0.01
6.3
5.3
7.80
7.75
%
0.05
133
1372
16
158
1.01
0.00
1.2
1.2
—
—
—
0
0
20
202
0.99
0.00
1.8
3.8
—
—
—
0
0
19
193
0.98
0.00
1.2
1.1
—
—
—
0
0
27
266
1.02
0.00
1.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.6
—
7.13
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
7.2
5.5
401.40
396.55
umol/l
—
5
40
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
0.00
—
0
6
7
73
0.96
-0.00
1.1
1.5
20.43
27.46
e6/l
—
7
56
0
5
0.00
-0.00
0.0
1.4
—
4.63
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
50.30
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
23.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
18.89
—
0
7
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.3
—
—
—
0
0
5
49
1.02
-0.00
1.8
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
77
0.91
-0.00
4.1
2.1
13.60
13.02
%
—
7
77
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint O15_PLAC_DISORD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PLAC_DISORD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: O15_PLAC_DISORD – Placental disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data