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Anxious personality disorder

DOID EFO Endpoint Browser PheWeb

F5_ANXPER

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60.6
  • Hospital discharge: ICD-9 — 3018C
  • Cause of death: ICD-10 — F60.6
  • Cause of death: ICD-9 — 3018C

2 out of 7 registries used, show all original rules.

753

4. Check minimum number of events

None

753

5. Include endpoints

None

753

6. Filter based on genotype QC (FinnGen only)

753

Control definitions (FinnGen only)

Control exclude
F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F60
Name in latin
Personalitas anxifera

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6586 3244 3328
Only index persons 6345 3173 3172
Unadjusted period prevalence (%)
Whole population 0.09 0.09 0.09
Only index persons 0.12 0.12 0.12
Median age at first event (years)
Whole population 31.88 31.84 31.90
Only index persons 31.54 31.61 31.48

-FinnGen-

Key figures

All Female Male
Number of individuals 753 472 281
Unadjusted period prevalence (%) 0.15 0.16 0.12
Median age at first event (years) 34.36 34.60 33.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
686
Matched controls
6860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F60.6
ICD-10 Finland
Anxious [avoidant] personality disorder
+∞
323.0
655
*
N05AH04
ATC
quetiapine; oral
15.3
209.3
424
656
F40.1
ICD-10 Finland
Social phobias
34.9
179.5
237
102
N06AX16
ATC
venlafaxine; oral
13.1
176.6
370
562
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
27.6
174.0
247
137
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
22.5
170.6
261
182
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
17.4
158.6
270
246
F32.9
ICD-10 Finland
Depressive episode, unspecified
11.2
151.4
339
549
N06AB04
ATC
citalopram; systemic
8.2
119.6
331
704
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
14.2
119.0
218
218
F34.1
ICD-10 Finland
Dysthymia
24.9
116.4
168
88
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
10.3
112.4
249
360
N05AH03
ATC
olanzapine; systemic
14.8
111.1
198
183
N06AB06
ATC
sertraline; oral
9.4
108.6
256
409
N06AB10
ATC
escitalopram; oral
6.7
107.4
363
988
N06AX11
ATC
mirtazapine; oral
6.2
104.8
401
1268
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
17.7
104.1
170
125
N06AB03
ATC
fluoxetine; oral
9.3
102.6
241
378
N05AX12
ATC
aripiprazole; systemic
16.6
99.8
167
130
N05BA04
ATC
oxazepam; oral
6.1
93.6
331
912
N06AX12
ATC
bupropion; oral
10.0
93.6
206
283
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
500.2
90.4
88
*
N05AX08
ATC
risperidone; systemic
12.7
90.3
171
174
F61.0
ICD-10 Finland
Mixed personality disorders
342.1
90.1
89
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.6
85.8
229
423
P76
ICPC
Depressive disorder
9.2
81.8
187
268
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
158.1
68.3
71
5
N03AX09
ATC
lamotrigine; oral
10.5
66.9
138
160
F41.1
ICD-10 Finland
Generalized anxiety disorder
9.1
66.7
151
207
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
6.1
66.5
209
461
F60.5
ICD-10 Finland
Anankastic personality disorder
64.5
65.2
75
13
N06AX21
ATC
duloxetine; oral
6.7
63.4
181
350
P03
ICPC
Feeling depressed
5.4
58.4
203
496
N05AB03
ATC
perphenazine; systemic, rectal
16.5
57.9
95
66
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
15.3
57.2
97
73
F60.9
ICD-10 Finland
Personality disorder, unspecified
155.1
54.7
57
*
P01
ICPC
Feeling anxious/nervous/tense
4.6
54.6
227
665
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
38.2
54.4
69
20
N05AA02
ATC
levomepromazine; systemic
18.0
54.3
86
54
N06AX26
ATC
vortioxetine; oral
7.3
53.3
139
232
F29
ICD-10 Finland
Unspecified nonorganic psychosis
10.2
52.3
108
123
T36
ICD-10 Finland
Poisoning by systemic antibiotics
10.5
51.6
105
116
N06AG02
ATC
moclobemide; oral
13.5
51.4
92
78
SPAT1240
SPAT
Therapeutic discussion
4.6
50.6
205
579
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
5.2
50.4
176
424
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
49.6
47
*
N06AB05
ATC
paroxetine; oral
7.6
47.6
119
185
P99
ICPC
Psychological disorders other
13.3
47.4
85
72
N06AX03
ATC
mianserin; oral
12.8
47.1
86
76
F60.8
ICD-10 Finland
Other specific personality disorders
489.6
46.9
46
*
C07AA05
ATC
propranolol; systemic
3.9
46.7
236
810
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
12.3
46.2
86
79
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
15.1
45.5
77
57
P29
ICPC
Psychological sympt/compl other
6.1
45.0
134
264
N05CF01
ATC
zopiclone; oral
3.6
43.9
246
912
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
11.5
43.3
83
81
F60.1
ICD-10 Finland
Schizoid personality disorder
+∞
43.2
41
*
F60.7
ICD-10 Finland
Dependent personality disorder
+∞
43.2
41
*
N05BA01
ATC
diazepam; systemic, rectal
5.2
43.0
149
350
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
14.7
42.8
73
55
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
10.8
42.0
83
86
N05BA06
ATC
lorazepam; systemic, sublingual
13.5
41.7
74
61
N05BE01
ATC
buspirone; oral
13.5
41.2
73
60
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
12.3
41.0
76
69
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.3
40.1
102
161
N03AE01
ATC
clonazepam; systemic
8.1
39.3
92
128
IGY02
NOMESCO Finland
Psychiatric monitoring contact
12.9
38.2
69
59
N03AG01
ATC
valproic acid; systemic, rectal
6.6
36.9
100
172
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
18.2
36.5
57
34
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.5
36.1
66
58
3018C
ICD-9 Finland
Personality disorders, Other personality disorders[ESTYNYT PERSOONALLISUUS]
+∞
35.7
34
*
N05AN01
ATC
lithium; oral
13.0
34.6
62
52
N05CD07
ATC
temazepam; oral
6.0
34.1
100
190
P74
ICPC
Anxiety disorder/anxiety state
6.4
31.8
88
155
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
9.6
31.6
66
75
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.2
31.3
63
67
F31.8
ICD-10 Finland
Other bipolar affective disorders
12.9
30.8
55
46
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
17.7
30.6
48
29
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
86.6
30.0
33
*
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
6.2
30.0
85
154
F40.01
ICD-10 Finland
Agoraphobia with concomitant panic disorder
22.8
29.9
43
20
N06AX22
ATC
agomelatine; oral
9.4
29.4
62
72
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
10.8
29.3
57
57
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
11.4
29.0
55
52
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
7.4
29.0
71
105
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
8.3
28.7
65
85
SPAT1307
SPAT
Psychosocial counselling and guidance
3.9
28.3
130
391
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
14.8
28.0
47
34
N07BB01
ATC
disulfiram; oral
7.0
27.6
70
109
N05BA12
ATC
alprazolam; oral
4.3
27.5
109
286
N06AX05
ATC
trazodone; oral
10.2
27.0
54
57
F10.20
ICD-10 Finland
Alcohol dependence currently independent
16.3
26.7
43
28
N05AF03
ATC
chlorprothixene; systemic
10.0
26.7
54
58
AA400
NOMESCO Finland
Electroconvulsive therapy
19.2
26.4
40
22
P72
ICPC
Schizophrenia
12.2
25.3
46
40
F99
ICD-10 Finland
Mental disorder, not otherwise specified
9.6
25.2
52
58
F43.1
ICD-10 Finland
Post-traumatic stress disorder
7.1
24.4
61
93
F41.00
ICD-10 Finland
Moderate panic disorder
10.6
23.1
45
45
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
14.8
22.9
38
27
N06AA12
ATC
doxepin; systemic
7.0
22.6
57
88
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
22.3
22.3
32
15
N05AH02
ATC
clozapine; systemic
8.4
22.1
49
62
F21
ICD-10 Finland
Schizotypal disorder
32.4
21.6
28
9
IGY99
NOMESCO Finland
Other psychiatric treatment contact
9.7
21.6
44
48
F33.8
ICD-10 Finland
Other recurrent depressive disorders
19.7
21.5
32
17
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
9.3
21.2
44
50
N06AB08
ATC
fluvoxamine; oral
10.6
21.1
41
41
N03AX16
ATC
pregabalin; oral
2.7
20.8
166
727
N05CF02
ATC
zolpidem; oral
2.8
20.6
149
616
P80
ICPC
Personality disorder
33.7
20.3
26
8
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
16.7
20.3
32
20
F32.1
ICD-10 Finland
Moderate depressive episode
3.9
19.9
87
248
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
10.3
19.8
39
40
N05AD01
ATC
haloperidol; systemic
12.7
19.8
35
29
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
12.7
19.8
35
29
P28
ICPC
Limited function/disability (P)
25.5
19.7
27
11
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
9.6
19.6
40
44
SPAT1234
SPAT
Support of social functional capacity
6.9
19.4
49
76
F32
ICD-10 Finland
Depressive episode
4.3
19.4
75
191
N05AL01
ATC
sulpiride; systemic
12.7
19.3
34
28
F32.8
ICD-10 Finland
Other depressive episodes
10.0
19.1
38
40
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
15.4
19.1
31
21
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.8
18.7
137
565
N06AX18
ATC
reboxetine; oral
20.0
18.3
27
14
N05AF01
ATC
flupentixol; systemic
14.9
18.2
30
21
F20.9
ICD-10 Finland
Schizophrenia, unspecified
8.3
18.0
40
51
F39
ICD-10 Finland
Unspecified mood [affective] disorder
6.9
17.7
44
67
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
16.2
17.6
28
18
F50.9
ICD-10 Finland
Eating disorder, unspecified
10.5
17.6
34
34
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.7
17.6
81
241
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
12.4
17.5
31
26
N05AE04
ATC
ziprasidone; systemic
24.8
17.4
24
10
P06
ICPC
Sleep disturbance
3.1
17.1
104
379
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
7.6
16.7
39
54
L17
ICPC
Foot/toe symptom/complaint
2.3
16.6
177
890
F40.00
ICD-10 Finland
Agoraphobia without concomitant panic disorder
28.3
16.6
22
8
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
9.8
16.6
33
35
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
18.5
16.6
25
14
N06AA09
ATC
amitriptyline; systemic
3.6
16.5
77
231
F64.9
ICD-10 Finland
Gender identity disorder, unspecified
+∞
15.7
15
*
F33
ICD-10 Finland
Recurrent depressive disorder
6.6
15.6
40
64
IEV99
NOMESCO Finland
Other psychiatric network intervention
39.0
15.4
19
5
F41.09
ICD-10 Finland
UNS Panic Syndrome
5.3
15.3
47
94
N06AX17
ATC
milnacipran; oral
14.4
15.1
25
18
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
7.9
15.1
34
45
F61
ICD-10 Finland
Mixed and other personality disorders
58.0
14.8
17
*
N05AD03
ATC
melperone; systemic
18.9
14.8
22
12
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
14.6
14
*
SPAT1243
SPAT
Psychiatric/psychological examination
4.6
14.6
51
118
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
43.5
14.2
17
*
F84.5
ICD-10 Finland
Asperger syndrome
11.2
14.1
26
24
N06AA06
ATC
trimipramine; systemic
7.8
14.1
32
43
N05BA02
ATC
chlordiazepoxide; systemic
10.8
13.8
26
25
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
10.0
13.8
27
28
H03AA01
ATC
levothyroxine sodium; systemic
2.2
13.8
152
773
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
15.1
13.6
22
15
P15
ICPC
Chronic alcohol abuse
6.7
13.5
34
53
F50.3
ICD-10 Finland
Atypical bulimia nervosa
19.5
13.0
19
10
N05AC02
ATC
thioridazine; oral
6.2
12.9
34
57
SPAT1252
SPAT
Overall medication plan or its review
4.7
12.8
43
96
F51.0
ICD-10 Finland
Nonorganic insomnia
2.3
12.7
123
585
IBZ08
NOMESCO Finland
Gender identity assessment
+∞
12.5
12
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
12.4
86
339
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.5
12.4
105
467
IBA03
NOMESCO Finland
Psychotherapy evaluation
9.2
12.3
25
28
F10.24
ICD-10 Finland
Alcohol depence active use
9.9
12.3
24
25
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.5
12.3
99
429
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
11.9
158
862
N04AA02
ATC
biperiden; systemic
8.1
11.9
26
33
F10.25
ICD-10 Finland
Alcohol dependence continuous use
8.6
11.9
25
30
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
15.0
11.8
19
13
SPAT1301
SPAT
No procedures
1.9
11.8
208
1267
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
16.8
11.7
18
11
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.3
11.7
25
31
F50.0
ICD-10 Finland
Anorexia nervosa
11.4
11.6
21
19
F22.0
ICD-10 Finland
Delusional disorder
9.5
11.6
23
25
IGY02
SPAT
NA
13.9
11.5
19
14
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
15.4
11.4
18
12
IGV01
NOMESCO Finland
Psychiatric network contact
9.8
11.3
22
23
S18
ICPC
Laceration/cut
1.8
11.3
241
1566
SPAT1241
SPAT
Extensive assessment of psychosocial situation
7.0
11.2
27
40
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
17.4
11.2
17
10
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
11.2
235
1516
T82
ICPC
Obesity
3.9
11.2
45
120
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
11.0
63
1305
IEY01
NOMESCO Finland
Psychoeducation, individual
12.2
10.9
19
16
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
18.2
10.8
16
9
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
21.9
10.7
15
7
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
10.6
130
684
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
7.5
10.5
24
33
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
14.5
10.5
17
12
P27
ICPC
Fear of mental disorder
6.5
10.4
26
41
N06AA04
ATC
clomipramine; systemic
8.4
10.4
22
27
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
33.1
10.4
13
*
P58
ICPC
Psychological, Therapeutic counselling/listening
5.6
10.2
29
54
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
10.2
54
180
X78
ICD-10 Finland
Intentional self-harm by sharp object
13.4
10.2
17
13
F50.2
ICD-10 Finland
Bulimia nervosa
8.6
10.1
21
25
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
10.0
49
154
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
14.9
10.0
16
11
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.1
10.0
38
97
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.4
9.9
29
56
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
9.9
48
150
F41.08
ICD-10 Finland
Mild or other specified panic syndrome
12.4
9.9
17
14
A29
ICPC
General symptom/complaint other
2.6
9.9
72
293
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
3.8
9.9
41
113
A04
ICPC
Weakness/tiredness general
2.2
9.9
103
505
IBB03
NOMESCO Finland
Assessment of vocational rehabilitation needs in a mental health context
20.4
9.8
14
7
N05AA01
ATC
chlorpromazine; systemic, rectal
10.8
9.8
18
17
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
9.7
9.8
19
20
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
9.8
72
296
F41.3
ICD-10 Finland
Other mixed anxiety disorders
5.7
9.7
27
49
A01
ICPC
Pain general/multiple sites
3.0
9.7
55
191
C07AB07
ATC
bisoprolol; oral
1.8
9.6
192
1213
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
10.2
9.6
18
18
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
17.8
9.4
14
8
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.5
9.4
64
1255
SPAT1310
SPAT
Counselling related to known health issue
1.8
9.2
212
1394
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
9.1
136
774
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
15.8
9.1
14
9
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.2
9.0
46
150
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
18.9
9.0
13
7
A06AD11
ATC
lactulose; oral
2.6
8.9
66
270
IFB02
NOMESCO Finland
Transcranial magnetic stimulation (TMS)
24.4
8.9
12
5
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.5
8.8
25
47
SPAT1216
SPAT
Assessment of functional ability
2.5
8.8
71
306
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
14.3
8.7
14
10
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
50.6
8.7
10
*
Z08
ICPC
Social welfare problem
7.8
8.7
19
25
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
8.7
66
277
SPAT1389
SPAT
Visit based on need for special support
3.3
8.7
42
132
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
8.4
8.6
18
22
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
8.6
137
796
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
8.6
110
587
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.3
8.5
42
134
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
27.9
8.5
11
*
F33.3
ICD-10 Finland
Recurrent depressive disorder, current episode severe with psychotic symptoms
20.3
8.5
12
6
F28
ICD-10 Finland
Other nonorganic psychotic disorders
20.3
8.5
12
6
SPAT1197
SPAT
Extensive health check-up of expecting family
0.4
8.5
36
844
EBA00
NOMESCO Finland
Extraction of tooth
1.7
8.4
242
1687
E66.8
ICD-10 Finland
Other obesity
2.9
8.4
50
181
WX307
NOMESCO Finland
Obstetric epidural analgesia
0.3
8.4
13
486
F31
ICD-10 Finland
Bipolar affective disorder
6.8
8.4
20
30
N03AX11
ATC
topiramate; oral
4.4
8.4
29
68
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.6
8.4
23
42
R96
ICPC
Asthma
2.7
8.3
57
226
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
0.5
8.3
53
1067
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
14.7
8.2
13
9
N05AE05
ATC
lurasidone; oral
14.7
8.2
13
9
KMAK
NOMESCO Finland
NA
1.6
8.2
379
2993
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.5
8.2
60
1154
R53
ICD-10 Finland
Malaise and fatigue
1.9
8.2
126
723
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
8.1
143
858
Z50.7
ICD-10 Finland
Occupational therapy and vocational rehabilitation, not elsewhere classified
17.4
8.1
12
7
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.1
8.1
24
48
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
8.1
110
601
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
22.3
8.0
11
5
F45.0
ICD-10 Finland
Somatization disorder
22.3
8.0
11
5
F50.1
ICD-10 Finland
Atypical anorexia nervosa
7.4
8.0
18
25
OAB43
SPAT
NA
0.5
7.9
55
1075
T90
ICPC
Diabetes non-insulin dependent
2.1
7.9
94
489
R02
ICPC
Shortness of breath/dyspnoea
2.3
7.9
71
325
N05AB01
ATC
dixyrazine; systemic
8.6
7.8
16
19
P18
ICPC
Medication abuse
9.6
7.8
15
16
IER01
NOMESCO Finland
Psychoeducation, group
9.6
7.8
15
16
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.6
7.8
34
99
U05
ICPC
Urination problems other
4.2
7.8
28
69
W78
ICPC
Pregnancy
0.4
7.8
45
936
F93.89
ICD-10 Finland
Other childhood emotional disorders
7.5
7.7
17
23
P98
ICPC
Psychosis NOS/other
7.5
7.7
17
23
A10BA02
ATC
metformin; oral
1.9
7.7
113
636
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.7
240
1707
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
7.6
123
716
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
8.2
7.6
16
20
A11
ICPC
Chest pain NOS
3.1
7.6
41
140
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
18.6
7.6
11
6
SPAT1285
SPAT
Provision of consultation response
3.2
7.6
38
123
A28
ICPC
Limited function/disability NOS
2.8
7.6
48
180
N05BA05
ATC
potassium clorazepate; oral
12.0
7.6
13
11
P86
ICPC
Anorexia nervosa/bulimia
12.0
7.6
13
11
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
0.3
7.6
18
540
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
25.3
7.6
10
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
25.3
7.6
10
*
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
9.0
7.6
15
17
R06.0
ICD-10 Finland
Dyspnoea
1.9
7.5
122
713
L84
ICPC
Back syndrome without radiat pain
3.2
7.5
38
125
XA820
NOMESCO Finland
NA
80.9
7.4
8
*
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
7.8
7.4
16
21
K85
ICPC
Elevated blood pressure
2.4
7.4
61
269
G47.3
ICD-10 Finland
Sleep apnoea
1.9
7.3
117
677
N03AX12
ATC
gabapentin; oral
2.1
7.3
84
430
F50.8
ICD-10 Finland
Other eating disorders
11.0
7.3
13
12
F60.2
ICD-10 Finland
Dissocial personality disorder
+∞
7.3
7
*
F64.0
ICD-10 Finland
Transsexualism
+∞
7.3
7
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.3
502
4315
L03
ICPC
Low back symptom/complaint
1.7
7.2
156
997
S29
ICPC
Skin symptom/complaint other
1.9
7.1
102
569
S10
ICPC
Boil/carbuncle
2.8
7.1
43
159
D01
ICPC
Abdominal pain/cramps general
2.0
7.0
87
458
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.4
6.9
34
752
SPAT1053
SPAT
Memory test
3.3
6.9
32
99
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.1
6.9
78
396
V03AA01
ATC
NA
8.4
6.8
14
17
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
6.8
6.8
16
24
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
5.1
6.8
20
40
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
6.8
67
320
F40.2
ICD-10 Finland
Specific (isolated) phobias
6.2
6.8
17
28
SPAT1260
SPAT
Consultation of another employee
1.9
6.8
108
626
IEZ99
SPAT
NA
40.5
6.8
8
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
16.9
6.8
10
6
T65.9
ICD-10 Finland
Toxic effect: Toxic effect of unspecified substance
22.8
6.7
9
*
SPAT1284
SPAT
Extensive health certificate
3.2
6.7
33
107
S22
ICPC
Nail symptom/complaint
2.9
6.7
39
141
SPAT1360
SPAT
Extensive global examination
2.6
6.6
46
184
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
12.4
6.6
11
9
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
8.8
6.6
13
15
SPAT1254
SPAT
Administration of medicine
2.0
6.5
87
472
A27
ICPC
Fear of other disease NOS
3.3
6.5
30
93
M79.7
ICD-10 Finland
Fibromyalgia
3.7
6.4
26
72
RS220
NOMESCO Finland
NA
7.5
6.4
14
19
IEY06
NOMESCO Finland
Psychiatric treatment and rehabilitation coaching
14.5
6.4
10
7
D12
ICPC
Constipation
4.3
6.4
22
53
F20
ICD-10 Finland
Schizophrenia
8.3
6.4
13
16
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.6
6.3
17
31
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
11.2
6.3
11
10
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
6.3
153
1007
N06BA04
ATC
methylphenidate; oral
3.3
6.3
29
90
30188
ICD-8 Finland
Personality disorders, Alia definita
+∞
6.3
6
*
F19.26
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances periodic addiction
+∞
6.3
6
*
F13.21
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but staying in a controlling environment
+∞
6.3
6
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.2
105
619
RT250
NOMESCO Finland
NA
26.9
6.2
8
*
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
26.9
6.2
8
*
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
6.2
44
178
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
6.2
367
2986
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
6.2
198
1401
R33
ICD-10 Finland
Retention of urine
3.6
6.2
26
75
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.5
6.1
41
816
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.6
6.1
43
173
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
6.1
37
138
A02BC05
ATC
esomeprazole; systemic
1.6
6.1
205
1467
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
6.1
32
109
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
6.1
95
544
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
6.1
50
221
F41.01
ICD-10 Finland
Severe panic disorder
8.7
6.1
12
14
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
8.7
6.1
12
14
N05AF05
ATC
zuclopenthixol; systemic
6.8
6.1
14
21
P20
ICPC
Memory disturbance
3.3
6.1
28
87

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
381
1749
3.39
59.30
2.1
1.7
97.8
97.3
pmol/l
0.07
222
922
202
624
4.06
57.77
1.7
1.6
1098.1
1165.9
nmol/l
0.50
167
488
110
214
5.85
55.37
3.3
2.9
—
—
—
0
0
231
935
3.12
41.89
1.6
1.4
19.8
20.9
nmol/l
0.45
212
815
398
2172
2.77
41.03
6.4
5.9
1.2
1.2
mmol/l
0.75
349
1857
368
1941
2.75
40.41
5.5
5.2
1.2
1.2
mmol/l
0.66
330
1784
120
350
3.89
36.14
3.5
2.6
—
—
—
0
0
648
4746
3.62
35.69
5.2
3.8
14.3
14.5
pmol/l
1.64
617
4396
35
32
11.42
33.09
3.1
3.0
—
—
—
0
0
349
1950
2.47
31.96
5.1
4.5
37.2
37.1
g/l
0.13
318
1834
126
411
3.48
31.94
3.0
2.1
—
—
—
0
0
287
1476
2.53
31.34
3.2
3.2
7.2
8.6
mmol/l
4.31
249
1284
294
1539
2.49
30.80
2.7
3.1
2.3
2.4
mmol/l
0.33
263
1384
570
4110
2.59
27.93
7.4
6.6
74.4
73.6
u/l
0.22
538
3882
371
2242
2.29
27.11
2.8
2.3
69.6
73.0
nmol/l
1.37
349
2074
240
1207
2.45
26.78
2.4
2.0
2.5
2.7
mg/l
0.79
207
1031
693
5587
4.02
26.72
6.5
4.3
1.8
2.2
mu/l
0.81
665
5281
132
500
2.99
25.81
3.1
2.0
—
—
—
0
0
249
1298
2.37
25.43
3.5
3.6
7.4
7.4
ph
0.20
28
238
711
5912
4.63
24.38
16.0
9.9
139.6
139.6
mmol/l
0.15
695
5747
135
535
2.86
24.22
3.1
2.0
—
—
—
0
0
133
525
2.86
24.03
1.7
2.0
352.9
380.4
nmol/l
0.86
121
488
136
544
2.83
23.97
3.1
1.9
—
—
—
0
0
711
5938
4.54
23.64
15.9
9.9
3.9
3.9
mmol/l
3.55
692
5755
135
542
2.82
23.60
3.1
1.9
—
—
—
0
0
682
5571
3.38
23.01
5.1
3.3
5.9
5.7
mmol/l
2.02
648
5207
183
888
2.40
21.51
1.8
1.5
425.8
23308701.1
pmol/l
1.06
159
798
235
1273
2.23
21.30
3.9
3.0
1.0
1.0
kg/l
0.69
28
171
23
22
10.75
20.98
2.3
2.3
169.0
170.0
umol/l
0.00
12
11
129
536
2.70
20.97
2.8
1.9
—
—
—
0
0
277
1613
2.13
20.82
3.3
2.4
54.6
56.3
u/l
0.39
252
1506
131
555
2.65
20.47
5.0
5.7
1.1
1.0
mmol/l
0.52
121
518
491
3622
2.02
18.30
3.8
2.9
—
—
—
0
0
30
48
6.47
18.13
2.7
1.9
—
—
—
0
0
56
156
3.80
17.74
1.4
1.2
—
—
—
0
0
413
2904
1.93
17.31
7.0
5.6
0.0
0.0
e9/l
0.07
361
2561
382
2618
1.93
17.29
5.5
5.4
10.0
10.5
umol/l
0.25
360
2472
421
3008
1.91
16.50
5.0
4.0
6.4
6.4
mmol/l
0.16
393
2732
409
2895
1.90
16.50
7.0
5.6
0.6
0.5
e9/l
0.31
358
2557
421
3019
1.89
16.20
8.2
5.9
0.2
0.2
e9/l
0.67
370
2701
415
2974
1.88
15.88
3.1
2.7
88.4
89.1
ug/l
0.02
388
2818
452
3340
1.88
15.59
12.1
8.3
4.0
4.0
e9/l
0.09
394
2943
141
697
2.26
15.45
3.0
3.2
0.8
0.8
mmol/l
0.00
132
656
419
3034
1.86
15.29
7.7
5.6
2.0
2.0
e9/l
0.21
371
2722
536
4204
1.95
15.19
4.2
3.5
11.0
8.8
mm/h
3.60
502
3931
130
628
2.29
15.02
2.4
2.2
2.4
2.4
g/l
0.12
117
584
137
677
2.25
14.99
2.6
2.2
15.0
14.6
umol/l
0.23
129
630
283
1823
1.88
14.88
5.8
5.6
—
—
—
0
0
225
1344
1.96
14.85
2.4
2.0
184.4
220.1
u/l
0.29
211
1277
116
571
2.22
12.71
2.4
2.2
27.2
24.6
%
0.77
95
498
723
6541
3.64
12.32
11.7
8.1
29.1
27.8
u/l
0.68
710
6360
600
5036
1.94
12.04
5.7
4.3
38.0
38.1
mmol/mol
0.14
565
4805
197
1211
1.85
11.50
3.6
4.2
23.8
13.3
mg/mmol
0.56
111
795
35
1020
0.31
11.36
1.2
1.3
—
—
—
0
0
189
1152
1.86
11.31
3.2
3.4
1322.0
193.2
mg/l
0.93
102
768
249
1656
1.75
11.10
1.4
1.3
3.2
1.6
u/ml
0.35
52
456
85
390
2.33
10.96
7.3
8.5
1.6
0.9
mmol/l
1.26
65
300
165
2563
0.54
10.71
2.8
2.3
—
—
—
0
0
83
383
2.31
10.56
2.2
1.5
413.9
290.0
mu/l
1.55
68
344
60
239
2.64
10.45
2.2
2.4
101.3
123.2
ng/l
0.26
52
209
75
334
2.38
10.34
7.6
9.2
125.9
125.0
g/l
0.14
70
320
96
478
2.16
10.15
7.1
5.9
104.1
104.4
mmol/l
0.23
90
468
354
2634
1.65
10.14
7.6
5.6
0.7
0.7
%
0.20
331
2485
365
2753
1.63
9.79
7.1
5.5
2.9
2.8
%
0.38
342
2586
214
1411
1.72
9.61
1.9
1.6
1.6
1.4
mmol/l
0.92
189
1228
668
5950
2.09
9.47
4.9
3.8
2.9
2.9
mmol/l
0.35
627
5633
365
2768
1.62
9.47
7.7
5.7
8.3
8.2
%
0.53
343
2628
217
1443
1.71
9.42
1.5
1.4
2.1
2.1
g/l
0.12
118
933
663
5916
2.01
8.95
4.5
3.5
4.7
4.8
mmol/l
1.06
632
5634
76
363
2.22
8.90
3.1
2.5
1.6
1.7
%
0.23
69
330
82
404
2.16
8.89
2.5
3.6
—
—
—
0
0
127
732
1.88
8.89
2.5
2.4
2.4
2.4
mmol/l
0.07
110
636
83
411
2.15
8.88
2.8
2.3
0.2
0.2
g/l
1.14
70
386
12
15
8.11
8.88
1.9
2.1
15.4
17.6
umol/l
0.24
12
15
659
5890
1.95
8.52
4.4
3.5
1.4
1.5
mmol/l
4.40
619
5600
374
2900
1.58
8.52
7.2
5.4
30.1
29.6
%
0.38
347
2751
370
2867
1.57
8.42
7.0
5.3
55.3
56.2
%
0.88
348
2721
72
346
2.20
8.31
4.8
3.3
2.3
1.8
mmol/l
0.47
64
281
53
226
2.45
8.05
4.9
2.9
129.9
134.0
g/l
0.59
53
221
51
217
2.45
7.78
8.1
7.0
—
—
—
0
0
207
1432
1.61
7.46
2.9
2.3
—
—
—
0
0
458
3787
1.53
7.36
4.6
3.6
2597.0
531.5
e6/l
0.35
11
38
7
0
+∞
7.30
1.4
0.0
307.4
—
nmol/l
—
7
0
35
128
2.82
7.22
1.6
2.8
—
—
—
0
0
132
819
1.74
7.18
3.3
3.1
177.6
622.4
ng/l
1.31
78
496
631
5638
1.74
7.17
3.9
3.2
1.4
1.3
mmol/l
5.86
588
5354
77
403
2.01
7.12
15.0
14.2
1.1
1.2
inr
0.21
13
69
70
358
2.05
6.89
4.0
3.0
—
—
—
0
0
53
247
2.23
6.61
2.0
2.6
71.7
71.6
e9/l
0.01
42
176
62
1148
0.50
6.56
1.5
1.5
—
—
—
0
0
174
1187
1.61
6.55
3.3
2.8
—
—
—
0
0
56
269
2.17
6.49
2.7
2.2
4.2
8.3
ug/l
1.56
48
242
33
124
2.74
6.49
1.7
1.4
—
—
—
0
0
194
1374
1.55
6.18
6.5
6.1
—
—
—
0
0
225
1650
1.52
6.10
9.1
5.7
1.1
1.1
inr
0.52
44
544
672
6184
1.81
5.98
14.5
9.9
21.2
20.3
mg/l
0.27
490
4730
61
315
2.02
5.87
6.0
7.2
—
—
—
0
0
99
601
1.75
5.78
1.2
1.2
—
—
—
0
0
63
333
1.97
5.69
1.5
1.4
—
—
—
0
0
33
134
2.53
5.60
11.2
4.5
—
—
—
0
0
160
1120
1.54
5.29
4.2
3.7
—
—
—
0
0
603
5445
1.54
5.24
18.5
12.0
13.6
13.3
%
2.04
593
5343
11
23
4.84
5.02
1.5
1.3
156.9
150.4
nmol/l
0.10
11
23
742
7149
3.59
4.86
24.2
14.4
89.6
89.9
fl
0.84
736
7078
742
7150
3.58
4.83
24.3
14.4
4.6
4.6
e12/l
0.03
727
6992
8
7
11.53
4.79
1.5
1.9
—
—
—
0
0
99
633
1.65
4.77
1.8
1.5
—
—
—
0
0
742
7155
3.54
4.72
24.4
14.5
137.2
137.9
g/l
0.75
736
7079
742
7157
3.52
4.68
24.3
14.5
6.8
6.6
e9/l
1.01
727
6998
741
7142
3.35
4.68
24.5
14.5
264.7
258.1
e9/l
1.91
728
6994
98
629
1.64
4.66
2.2
2.3
9.5
6.7
umol/l
0.47
82
531
39
188
2.13
4.54
7.8
10.8
—
—
—
0
0
741
7149
3.29
4.53
24.2
14.4
30.0
30.1
pg
1.25
735
7077
82
508
1.69
4.46
2.4
2.3
11.7
13.6
nmol/l
1.14
67
478
466
4063
1.39
4.44
4.3
3.7
—
—
—
0
0
32
144
2.28
4.40
1.7
1.4
528.1
314.9
ug/g
0.40
16
76
37
179
2.12
4.28
5.2
2.3
0.7
0.7
%
0.04
37
174
133
942
1.50
4.12
2.4
2.5
91.1
111.3
ug/g
0.48
101
744
103
692
1.57
4.06
1.2
1.2
—
—
—
0
0
23
512
0.43
4.03
1.7
1.7
—
—
—
0
0
172
1292
1.43
3.92
3.7
3.3
94.0
96.2
%
0.55
166
1251
314
2607
1.35
3.90
8.7
7.7
0.0
0.0
e9/l
0.11
255
2129
94
632
1.56
3.70
1.7
1.9
28.7
29.3
s
0.59
89
611
169
1279
1.41
3.68
4.0
2.9
—
—
—
0
0
49
277
1.82
3.68
1.4
1.3
—
—
—
0
0
58
345
1.74
3.68
1.7
1.8
1.2
1.4
g/l
0.47
50
320
65
400
1.68
3.65
2.3
3.6
4.5
4.7
pmol/l
0.89
59
363
46
256
1.85
3.63
2.3
2.4
7.4
7.4
ph
—
8
36
70
440
1.65
3.63
3.0
2.6
10.8
10.5
g/l
0.33
59
402
62
381
1.68
3.51
1.4
1.2
—
—
—
0
0
233
1876
1.35
3.46
3.1
3.0
20.0
85.2
e6/l
1.93
151
1232
136
1005
1.43
3.37
2.4
2.2
6.3
7.8
e6/l
0.50
122
883
98
680
1.51
3.34
2.2
2.0
—
—
—
0
0
695
6626
1.63
3.26
14.7
9.1
—
—
—
0
0
165
1273
1.38
3.18
2.2
2.2
2397.8
4634.5
umol/l
0.46
148
1159
9
21
4.32
3.00
2.2
5.3
—
—
—
0
0
189
1507
1.34
2.94
5.9
4.1
—
—
—
0
0
209
1694
1.32
2.90
3.9
2.7
21.2
38.6
ng/l
0.80
105
843
15
58
2.62
2.89
1.5
1.4
—
—
—
0
0
52
324
1.65
2.83
2.6
3.3
1.2
1.2
mmol/l
0.17
41
284
25
124
2.05
2.79
1.4
1.1
—
—
—
0
0
140
1074
1.37
2.79
1.8
1.6
—
—
—
0
0
5
6
8.38
2.75
4.4
11.3
—
—
—
0
0
48
296
1.66
2.73
1.3
1.4
6.7
8.3
u/l
0.65
40
245
63
417
1.56
2.69
3.8
2.1
4.1
4.2
e9/l
0.06
46
361
16
347
0.45
2.69
1.1
1.5
—
—
—
0
0
37
613
0.58
2.67
1.2
1.3
—
—
—
0
0
60
397
1.56
2.58
1.6
1.3
18.0
21.0
iu/l
0.32
43
334
16
340
0.46
2.55
1.1
1.4
—
—
—
0
0
12
44
2.76
2.55
2.1
1.3
—
—
—
0
0
16
338
0.46
2.52
1.1
1.4
—
—
—
0
0
23
117
2.00
2.42
1.2
1.1
—
—
—
0
0
115
876
1.37
2.39
1.3
1.4
268.9
493.4
titre
2.63
18
164
18
85
2.15
2.30
1.8
2.8
—
—
—
0
0
26
141
1.87
2.30
3.3
2.0
4.5
3.2
ug/l
0.16
26
130
74
526
1.45
2.28
2.5
2.4
28.9
128.0
u/l
0.55
65
441
166
1345
1.30
2.27
2.5
2.6
0.3
0.3
e6/l
0.11
122
986
31
179
1.76
2.26
1.8
2.4
—
—
—
0
0
76
548
1.43
2.18
1.1
1.2
87.2
142.3
iu/ml
1.03
26
218
334
2954
1.23
2.16
3.7
2.9
0.0
0.0
estimate
0.00
43
584
74
532
1.43
2.16
2.4
2.3
3517.6
3822.4
u/l
0.04
16
224
14
61
2.32
2.15
2.6
2.3
—
—
—
0
0
31
182
1.73
2.14
5.6
8.8
23.8
24.1
mmol/l
0.21
25
171
41
261
1.60
2.11
2.1
3.0
67.9
68.3
g/l
0.19
36
242
5
10
5.02
2.07
1.0
1.0
6.9
7.2
nmol/l
—
5
10
80
591
1.40
2.02
1.4
1.4
—
—
—
0
0
13
57
2.30
1.98
1.3
1.4
—
—
—
0
0
16
77
2.10
1.97
2.0
2.1
16.2
17.0
%
0.41
11
41
179
1492
1.26
1.95
2.8
2.6
33.9
57.9
e6/l
0.51
134
1119
8
182
0.43
1.83
1.1
1.1
—
—
—
0
0
8
182
0.43
1.83
1.1
1.1
—
—
—
0
0
11
47
2.36
1.78
1.0
1.0
—
—
—
0
0
14
67
2.11
1.77
1.1
1.4
—
—
—
0
0
18
95
1.92
1.76
1.3
2.1
0.5
0.9
g/l
0.95
13
76
114
1411
0.77
1.76
2.1
1.8
—
—
—
0
0
6
18
3.35
1.75
1.8
1.1
—
—
—
0
0
12
54
2.24
1.74
1.8
1.4
—
—
—
0
0
12
54
2.24
1.74
1.8
1.4
—
—
—
0
0
12
54
2.24
1.74
1.8
1.4
—
—
—
0
0
12
54
2.24
1.74
1.8
1.4
—
—
—
0
0
8
30
2.68
1.72
1.0
1.1
—
—
—
0
0
185
1569
1.24
1.72
4.4
3.1
0.0
0.0
estimate
1.28
46
589
332
2989
1.20
1.68
3.8
3.0
0.0
0.0
estimate
0.50
42
573
18
98
1.86
1.63
2.5
2.5
—
—
—
0
0
329
2967
1.19
1.62
4.9
4.1
0.0
0.0
estimate
0.50
48
606
25
151
1.68
1.61
1.4
1.5
0.3
0.3
nmol/l
0.57
16
127
6
20
3.02
1.58
1.2
1.1
—
—
—
0
0
35
235
1.51
1.49
2.9
2.2
0.1
0.1
e6/l
1.46
35
224
183
2109
0.83
1.47
1.4
1.7
—
—
—
0
0
12
59
2.05
1.44
1.0
1.1
—
—
—
0
0
5
16
3.14
1.44
2.0
7.0
—
—
—
0
0
160
1363
1.22
1.42
2.5
2.5
—
—
—
0
0
22
134
1.66
1.40
1.4
1.3
12.6
653.1
e6/l
0.63
17
108
22
134
1.66
1.40
1.3
1.2
1.7
8.7
e6/l
1.74
16
104
8
35
2.30
1.27
4.5
3.3
—
—
—
0
0
54
408
1.35
1.26
6.1
4.3
0.1
0.0
%
0.14
14
91
79
631
1.28
1.25
1.5
1.4
—
—
—
0
0
8
36
2.24
1.24
2.0
1.5
16.4
7.0
ug/l
—
8
30
13
70
1.87
1.24
1.2
1.6
—
—
—
0
0
27
180
1.52
1.22
1.4
1.3
—
—
—
0
0
10
49
2.05
1.22
1.1
1.2
—
—
—
0
0
28
189
1.50
1.20
2.1
1.8
192.5
226.9
pmol/l
0.94
28
181
58
448
1.32
1.18
6.0
4.1
1.4
0.9
%
0.34
17
119
22
332
0.65
1.17
1.0
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
1.1
—
—
—
0
0
12
65
1.86
1.14
1.0
1.4
—
—
nmol/l
—
0
0
11
59
1.88
1.07
1.2
1.3
—
—
—
0
0
19
121
1.59
1.06
1.1
1.3
—
—
—
0
0
9
48
1.89
1.00
1.6
2.9
0.2
0.2
e9/l
—
9
43
17
107
1.60
1.00
1.1
1.1
1.0
151.7
iu/ml
—
5
33
9
49
1.85
0.99
1.1
1.1
—
—
—
0
0
26
364
0.70
0.97
1.6
1.3
—
—
—
0
0
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
10
54
1.86
0.97
1.1
1.9
—
—
—
0
0
0
31
0.00
0.96
0.0
2.5
—
501.4
—
0
22
9
51
1.77
0.94
1.6
2.8
453.0
564.6
e6/l
—
9
44
54
428
1.28
0.94
6.2
4.2
0.1
0.1
%
0.02
16
108
27
373
0.71
0.94
1.6
1.3
185.3
237.5
miu/ml
—
10
186
6
119
0.50
0.94
1.5
1.1
—
—
—
0
0
24
167
1.45
0.93
1.8
3.3
0.6
0.3
g/l
—
6
76
10
56
1.80
0.88
1.0
2.0
—
—
—
0
0
52
417
1.27
0.85
5.3
3.9
0.4
0.4
%
0.17
11
88
6
114
0.52
0.83
1.5
1.2
—
—
—
0
0
6
32
1.88
0.82
1.7
1.6
15.0
12.4
%
—
6
32
161
1784
0.88
0.78
3.2
2.6
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
44
351
1.27
0.76
2.9
2.3
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
122
1078
1.16
0.75
1.4
1.2
19.6
27.4
iu/ml
0.67
39
332
80
683
1.19
0.74
1.5
1.5
—
—
—
0
0
122
1079
1.16
0.74
3.0
3.3
1.3
1.8
ug/l
0.92
110
1006
8
132
0.60
0.74
1.0
1.2
—
—
—
0
0
16
108
1.49
0.74
4.8
3.2
14.0
26.4
mg/l
—
7
64
43
530
0.80
0.71
3.3
3.4
—
—
—
0
0
25
186
1.36
0.71
1.1
1.2
—
—
—
0
0
5
92
0.54
0.67
1.0
1.3
—
—
—
0
0
32
250
1.29
0.66
1.7
1.7
—
—
—
0
0
55
462
1.21
0.63
1.3
1.3
100.1
299.9
u/ml
2.39
47
426
53
629
0.83
0.62
2.3
2.3
0.5
0.7
ug/l
0.48
34
312
12
176
0.68
0.62
1.0
1.1
0.4
3.8
u/ml
—
6
48
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
106
945
1.14
0.60
2.3
2.3
530.0
563.9
mosm/kgh2o
0.75
92
812
0
22
0.00
0.59
0.0
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
16
114
1.41
0.59
1.8
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
6
37
1.63
0.55
1.5
3.3
—
—
—
0
0
27
214
1.27
0.53
2.2
2.5
—
—
—
0
0
12
83
1.45
0.52
1.1
1.6
—
—
—
0
0
115
1044
1.12
0.50
1.3
1.2
13.6
9.4
u/ml
0.20
29
439
6
41
1.47
0.50
1.7
2.8
0.1
0.2
e9/l
—
6
41
10
67
1.50
0.50
6.2
2.2
7.5
7.1
mmol/l
—
10
67
7
45
1.56
0.49
1.3
2.3
—
—
—
0
0
25
199
1.27
0.48
2.0
2.0
—
—
—
0
0
16
122
1.32
0.42
2.2
1.8
—
—
—
0
0
42
360
1.18
0.42
1.3
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
14
183
0.76
0.41
2.1
2.0
3.0
5.3
iu/l
—
7
68
11
79
1.40
0.41
1.2
1.3
—
30.9
—
0
5
10
138
0.72
0.40
1.1
1.1
—
9.6
—
0
15
7
102
0.68
0.39
2.0
2.6
—
—
—
0
0
161
1716
0.92
0.39
1.9
1.7
—
—
—
0
0
16
204
0.78
0.39
1.1
1.1
0.2
2.7
u/ml
—
8
80
5
35
1.43
0.39
1.4
1.2
—
—
—
0
0
140
1304
1.09
0.39
1.6
1.7
0.9
0.9
mg/l
0.12
95
929
9
66
1.37
0.38
4.2
4.2
—
—
—
0
0
23
188
1.23
0.38
25.2
7.8
—
—
—
0
0
5
37
1.35
0.37
1.4
2.5
—
2.2
—
0
7
6
43
1.40
0.35
1.2
1.1
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
12
92
1.31
0.32
2.6
2.2
8.7
9.4
kpa
1.12
12
92
17
207
0.82
0.30
1.1
1.1
—
—
—
0
0
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
26
223
1.17
0.28
1.2
1.6
—
7.1
—
0
11
24
208
1.16
0.24
1.5
1.9
19.8
21.3
s
1.38
18
179
22
190
1.16
0.23
1.1
1.2
—
—
—
0
0
29
326
0.89
0.22
1.1
1.1
—
—
—
0
0
5
42
1.19
0.21
4.2
2.0
—
—
—
0
0
5
42
1.19
0.21
4.2
2.0
3.9
4.0
mmol/l
—
5
42
5
42
1.19
0.21
4.2
2.0
103.4
105.3
mmol/l
—
5
42
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.2
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
208
2150
0.96
0.21
2.4
2.1
—
—
—
0
0
5
43
1.16
0.21
1.4
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
5.6
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
14
166
0.84
0.20
1.4
2.1
5.9
4.6
umol/l
—
8
129
136
1302
1.05
0.20
2.9
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
15
176
0.85
0.20
1.0
1.1
1.2
1.5
u/ml
—
8
78
16
185
0.86
0.18
1.0
1.1
8.4
8.7
u/ml
0.02
11
107
20
227
0.88
0.18
3.5
2.5
—
—
—
0
0
267
2736
0.96
0.18
4.6
3.8
—
—
—
0
0
88
835
1.06
0.18
1.9
1.9
—
—
—
0
0
11
91
1.21
0.17
4.2
2.5
—
—
—
0
0
44
408
1.08
0.16
1.4
1.2
—
25.0
—
0
17
11
130
0.84
0.16
1.5
1.7
—
—
—
0
0
11
93
1.19
0.14
2.9
2.2
2.3
2.5
mmol/l
—
6
54
11
93
1.19
0.14
2.9
2.2
5.3
4.9
kpa
1.53
11
93
13
112
1.16
0.14
1.2
1.3
—
—
—
0
0
36
334
1.08
0.14
2.2
4.5
6.3
19.4
ug/l
0.48
27
265
10
84
1.19
0.14
4.1
3.9
29.2
33.7
mg/l
—
10
67
13
147
0.88
0.11
2.0
1.4
—
—
—
0
0
31
329
0.94
0.09
1.2
1.2
—
—
—
0
0
221
2175
1.02
0.09
2.0
1.9
—
—
—
0
0
8
76
1.05
0.07
1.4
3.0
2.3
4.3
u/ml
—
8
65
7
80
0.87
0.07
1.9
2.1
—
—
—
0
0
9
84
1.07
0.07
4.4
3.9
23.1
28.2
mg/l
—
9
66
17
158
1.08
0.06
1.2
1.2
—
3.2
—
0
19
15
162
0.92
0.06
1.3
1.2
188.7
232.3
u/ml
—
8
96
14
129
1.09
0.05
1.0
1.1
—
—
—
0
0
168
1701
0.98
0.05
2.8
2.0
—
—
—
0
0
12
112
1.07
0.03
4.1
3.3
4.1
4.0
e9/l
0.10
12
112
63
640
0.98
0.02
1.2
1.2
—
—
—
0
0
619
6182
1.01
0.01
16.9
10.4
40.4
40.9
%
1.01
416
5149
10
94
1.06
0.01
4.9
3.0
—
—
—
0
0
12
114
1.05
0.00
4.2
3.6
56.0
55.9
%
0.01
12
114
12
126
0.95
0.00
1.2
1.1
—
—
—
0
0
27
264
1.02
0.00
1.4
1.5
—
—
—
0
0
10
104
0.96
0.00
1.2
1.2
—
—
—
0
0
65
647
1.01
0.00
1.5
1.4
—
—
—
0
0
7
71
0.99
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
9.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
67
0.89
0.00
4.8
4.3
—
53.3
—
0
22
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
5
49
1.02
0.00
2.4
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
194.6
—
0
5
0
6
0.00
0.00
0.0
4.3
—
11.8
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
6236.2
—
0
9
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
5.2
—
0.3
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint F5_ANXPER and mortality.

Females

Parameter HR [95% CI] p-value
F5_ANXPER 2.031 [1.64, 2.51] < 0.001
Birth year 0.994 [0.98, 1.0] 0.235

During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 2540 females with F5_ANXPER died.

Males

Parameter HR [95% CI] p-value
F5_ANXPER 2.306 [1.95, 2.72] < 0.001
Birth year 0.99 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 215 out of 2580 males with F5_ANXPER died.

Mortality risk

Mortality risk for people of age

years, who have F5_ANXPER.

N-year risk Females Males
1 0.19% 0.533%
5 1.135% 2.685%
10 2.929% 6.836%
15 5.855% 13.274%
20 10.102% 22.534%

Relationships between endpoints

↥

Index endpoint: F5_ANXPER – Anxious personality disorder

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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