Disorders of synovium and tendon in diseases classified elsewhere

M13_SYNOTENDINOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

774

4. Check minimum number of events

None

774

5. Include endpoints

None

774

6. Filter based on genotype QC (FinnGen only)

774

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5589 2480 3087
Only index persons 5300 2380 2920
Unadjusted period prevalence (%)
Whole population 0.08 0.07 0.09
Only index persons 0.10 0.09 0.11
Median age at first event (years)
Whole population 53.03 54.84 51.54
Only index persons 52.30 54.19 50.77

-FinnGen-

Key figures

All Female Male
Number of individuals 774 364 410
Unadjusted period prevalence (%) 0.15 0.12 0.18
Median age at first event (years) 53.54 53.45 53.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
687
Matched controls
6870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M71.9
ICD-10 Finland
Bursopathy, unspecified
2627.0
323.0
558
11
M71.8
ICD-10 Finland
Other specified bursopathies
+∞
124.9
116
*
M79.6
ICD-10 Finland
Pain in limb
4.3
57.2
271
908
M75.1
ICD-10 Finland
Rotator cuff syndrome
5.2
50.9
180
440
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
75.1
43.6
49
7
M70.2
ICD-10 Finland
Olecranon bursitis
15.7
37.5
62
43
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
34.9
350
1870
N02AX02
ATC
tramadol; systemic, rectal
2.6
30.7
316
1671
M01AH05
ATC
etoricoxib; oral
2.6
30.5
428
2692
M25.5
ICD-10 Finland
Pain in joint
2.9
29.6
218
935
M70.6
ICD-10 Finland
Trochanteric bursitis
4.9
27.8
96
219
N03AX16
ATC
pregabalin; oral
3.1
27.5
178
695
M70.4
ICD-10 Finland
Prepatellar bursitis
25.0
27.3
38
16
N03AX12
ATC
gabapentin; oral
3.8
27.1
126
382
M79.0
ICD-10 Finland
Rheumatism, unspecified
78.4
27.0
30
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
17.8
27.0
42
25
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.9
26.4
77
144
A46
ICD-10 Finland
Erysipelas
3.5
24.9
130
432
J01DB01
ATC
cefalexin; oral
2.8
24.8
583
4562
J01FF01
ATC
clindamycin; systemic
2.6
24.7
222
1055
M54.5
ICD-10 Finland
Low back pain
2.6
24.1
230
1129
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
129.5
23.7
25
*
S18
ICPC
Laceration/cut
2.3
23.3
305
1754
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.1
23.2
97
266
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
22.7
267
1450
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.7
22.6
81
191
M67.4
ICD-10 Finland
Ganglion
8.4
22.1
49
62
M48.0
ICD-10 Finland
Spinal stenosis
3.8
22.1
99
289
M71.0
ICD-10 Finland
Abscess of bursa
226.8
21.7
22
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.9
21.2
145
576
L17
ICPC
Foot/toe symptom/complaint
2.6
21.1
182
834
L15
ICPC
Knee symptom/complaint
2.7
20.2
155
663
M03BX02
ATC
tizanidine; oral
2.1
20.2
425
2963
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
59.3
20.0
23
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.7
18.8
150
654
A02BC02
ATC
pantoprazole; systemic
2.1
18.7
432
3082
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
7.7
18.5
43
59
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
18.3
259
1502
R07.4
ICD-10 Finland
Chest pain, unspecified
2.4
18.1
186
924
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.9
17.9
78
221
J01DA01
ATC
[U] cefalexin; systemic
2.0
17.8
427
3063
M01AB05
ATC
diclofenac; systemic, rectal
2.0
17.2
454
3357
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
17.0
135
583
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.9
16.9
73
205
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.9
16.9
109
415
N02BE01
ATC
paracetamol; systemic, rectal
2.3
16.7
574
4715
M71.1
ICD-10 Finland
Other infective bursitis
+∞
16.7
16
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.4
16.0
82
265
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
27.0
15.7
21
8
M03BC01
ATC
orphenadrine (citrate); systemic
2.3
15.2
159
791
M54.4
ICD-10 Finland
Lumbago with sciatica
2.7
15.1
111
456
WX320
NOMESCO Finland
Spinalanesthesy
2.3
15.0
166
847
X58
ICD-10 Finland
Exposure to other specified factors
2.8
14.9
105
421
M79.1
ICD-10 Finland
Myalgia
3.4
14.8
75
240
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.7
14.7
50
112
R06.0
ICD-10 Finland
Dyspnoea
2.3
14.7
160
810
ZXA00
NOMESCO Finland
Right side
2.2
14.6
180
965
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
3.2
14.5
81
278
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
14.5
200
1123
H02AB06
ATC
prednisolone; systemic
1.9
14.2
305
2030
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
14.2
181
982
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.5
14.1
50
117
L03
ICPC
Low back symptom/complaint
2.3
14.0
151
757
M79.7
ICD-10 Finland
Fibromyalgia
13.0
14.0
24
19
M01AH02
ATC
rofecoxib; oral
2.8
13.8
97
386
M01AE02
ATC
naproxen; oral, rectal
1.9
13.7
367
2623
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.3
13.6
50
122
L08
ICPC
Shoulder symptom/complaint
2.5
13.5
118
532
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.8
13.4
58
164
M01AH01
ATC
celecoxib; oral (coxibs)
2.4
13.4
121
557
P01BA02
ATC
hydroxychloroquine; oral
3.3
13.3
69
225
M01AC06
ATC
meloxicam; systemic, rectal
1.9
13.0
232
1430
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
13.3
13.0
22
17
M02AA07
ATC
piroxicam; topical
1.9
12.9
231
1425
SPAT1153
SPAT
Removal of sutures
2.0
12.9
216
1303
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
12.8
67
220
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.9
12.8
81
301
M13.9
ICD-10 Finland
Arthritis, unspecified
3.6
12.8
59
176
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.6
217
1320
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
12.5
185
1059
M01AE01
ATC
ibuprofen; systemic, rectal
2.2
12.5
600
5192
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.8
12.5
84
326
L28
ICPC
Limited function/disability (L)
2.5
12.0
99
431
XA402
NOMESCO Finland
ENMG
7.8
12.0
27
36
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
13.7
12.0
20
15
B01AB05
ATC
enoxaparin; parenteral
1.9
11.9
198
1183
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
5.5
11.8
34
64
N06AA09
ATC
amitriptyline; systemic
3.0
11.6
68
242
P01AB01
ATC
metronidazole; oral, rectal
1.8
11.6
248
1616
J01MA02
ATC
ciprofloxacin; systemic
1.8
11.5
250
1637
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
11.4
328
2351
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
11.2
177
1031
M01AX05
ATC
glucosamine; oral
2.2
11.0
121
606
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
11.0
93
409
N06AX21
ATC
duloxetine; oral
2.9
11.0
68
251
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
11.0
69
258
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.7
10.9
78
313
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
10.9
84
352
R03AC02
ATC
salbutamol; inhalant
1.7
10.9
320
2295
A01
ICPC
Pain general/multiple sites
3.4
10.9
53
166
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.6
10.8
78
317
M76.6
ICD-10 Finland
Achilles tendinitis
5.0
10.6
33
68
M70.7
ICD-10 Finland
Other bursitis of hip
8.7
10.6
22
26
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.5
10.4
87
381
NFM20
NOMESCO Finland
Excision of bursa of hip or thigh
111.6
10.4
11
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
111.6
10.4
11
*
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.2
10.4
55
183
L13
ICPC
Hip symptom/complaint
2.4
10.4
95
438
M01AX17
ATC
nimesulide; oral
2.0
10.4
149
837
R51.80
ICD-10 Finland
Headache
2.4
10.1
86
382
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
10.1
59
211
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
14.8
10.0
16
11
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
10.0
61
222
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
5.6
9.9
28
52
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.3
9.9
36
88
R60.0
ICD-10 Finland
Localized oedema
2.6
9.8
72
294
M70.3
ICD-10 Finland
Other bursitis of elbow
20.4
9.8
14
7
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
9.7
302
2178
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
9.3
9.6
19
21
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.1
9.6
36
91
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
9.5
176
1079
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.0
9.4
55
196
J01CA04
ATC
amoxicillin; systemic
1.7
9.3
518
4380
L10
ICPC
Elbow symptom/complaint
3.8
9.2
38
105
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
9.1
54
195
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.7
9.1
62
244
WX110
NOMESCO Finland
Local anesthesy
1.6
9.0
435
3512
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.0
433
3490
J01AA02
ATC
doxycycline; systemic
1.7
9.0
495
4144
ZXA05
NOMESCO Finland
Left side
1.9
9.0
153
909
M70.5
ICD-10 Finland
Other bursitis of knee
18.9
9.0
13
7
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
8.9
357
2738
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
8.9
269
1911
NBG10
NOMESCO Finland
Acromioplastia
14.3
8.7
14
10
WX203
NOMESCO Finland
Infraclavicular plexus blockade
6.3
8.7
22
36
N06AX11
ATC
mirtazapine; oral
1.8
8.6
194
1260
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
8.6
95
478
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.5
8.6
67
282
N06AB04
ATC
citalopram; systemic
1.9
8.6
132
758
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
8.6
137
797
UJF32
NOMESCO Finland
Coloscopy
1.8
8.5
159
975
C03CA01
ATC
furosemide; systemic
1.8
8.5
159
975
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.4
8.4
29
68
N02AA05
ATC
oxycodone; systemic
2.2
8.4
87
426
M65.3
ICD-10 Finland
Trigger finger
6.3
8.4
21
34
M66.0
ICD-10 Finland
Rupture of popliteal cyst
+∞
8.3
8
*
M68.8
ICD-10 Finland
Other disorders of synovium and tendon in diseases classified elsewhere
+∞
8.3
8
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
8.7
8.3
17
20
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.5
8.3
63
263
C07AB07
ATC
bisoprolol; oral
1.6
8.3
279
2029
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
8.3
130
751
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.0
8.3
25
51
R01AD09
ATC
mometasone; nasal
1.6
8.2
276
2004
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
14.7
8.2
13
9
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
4.4
8.2
28
65
M70.8
ICD-10 Finland
Other soft tissue disorders related to use, overuse and pressure
33.8
8.1
10
*
M71.3
ICD-10 Finland
Other bursal cyst
33.8
8.1
10
*
M79.9
ICD-10 Finland
Soft tissue disorder, unspecified
17.4
8.1
12
7
M71.5
ICD-10 Finland
Other bursitis, not elsewhere classified
22.3
8.0
11
5
R4120
NOMESCO Finland
Occupational therapy
3.1
8.0
43
146
N06AX16
ATC
venlafaxine; oral
2.2
7.9
85
420
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
3.7
7.9
33
93
A02BC05
ATC
esomeprazole; systemic
1.6
7.8
244
1732
L12
ICPC
Hand/finger symptom/complaint
2.2
7.8
81
396
L01
ICPC
Neck symptom/complaint
2.2
7.8
80
387
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.9
7.8
45
160
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.7
7.8
25
55
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
7.7
106
580
WX200
NOMESCO Finland
Interscalenous plexus blockade
6.0
7.7
20
34
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
45.5
7.7
9
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
7.7
96
505
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.7
235
1659
A02BC03
ATC
lansoprazole; oral
1.7
7.5
176
1153
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
7.5
168
1086
R07.3
ICD-10 Finland
Other chest pain
2.4
7.4
60
260
R05
ICD-10 Finland
Cough
1.9
7.4
114
653
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
9.5
7.3
14
15
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
9.5
7.3
14
15
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
+∞
7.3
7
*
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.7
7.3
23
50
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.3
141
873
S19
ICPC
Skin injury other
3.4
7.2
33
100
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.9
7.2
28
74
205
Kela drug reimbursment
Chronic hypertension
1.7
7.2
169
1106
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
7.2
24
55
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
7.2
268
1985
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.6
7.2
30
85
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
20.3
7.1
10
5
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
6.1
7.1
18
30
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
5.7
7.1
19
34
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
8.9
7.1
14
16
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
7.1
50
203
R42
ICD-10 Finland
Dizziness and giddiness
1.9
7.0
118
692
S80.0
ICD-10 Finland
Contusion of knee
3.0
7.0
40
140
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.0
7.0
21
43
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
4.5
7.0
23
52
G47.3
ICD-10 Finland
Sleep apnoea
1.8
7.0
139
866
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
7.0
116
680
L88
ICPC
Rheumatoid/seropositive arthritis
3.7
6.9
28
77
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
6.9
51
210
KMAK
NOMESCO Finland
NA
1.5
6.9
310
2391
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.6
6.9
29
83
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
3.7
6.8
28
78
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.8
99
551
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.1
6.8
25
63
A02BC01
ATC
omeprazole; systemic
1.7
6.8
161
1053
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
11.1
6.8
12
11
R02
ICPC
Shortness of breath/dyspnoea
2.2
6.8
67
321
J01MA12
ATC
levofloxacin; systemic
1.8
6.8
121
727
ZX140
NOMESCO Finland
Intra articular
16.9
6.8
10
6
A04
ICPC
Weakness/tiredness general
2.1
6.8
73
363
S21
ICPC
Skin texture symptom/complaint
2.1
6.7
75
380
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.3
6.7
23
55
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.0
6.6
25
65
Z01.2
ICD-10 Finland
Dental examination
1.6
6.6
237
1729
R4110
NOMESCO Finland
Physiotherapy
1.7
6.6
159
1047
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
12.4
6.6
11
9
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
12.4
6.6
11
9
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
8.8
6.6
13
15
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.6
121
736
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
6.6
150
974
M54.3
ICD-10 Finland
Sciatica
3.0
6.6
35
120
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
3.8
6.5
26
71
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
6.5
55
245
M02AA10
ATC
ketoprofen; topical
1.9
6.5
93
518
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.6
6.4
45
180
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.8
6.4
20
43
E0000UV
ATC
NA
1.6
6.4
235
1718
M20.2
ICD-10 Finland
Hallux rigidus
3.8
6.4
25
67
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.5
6.4
28
83
M54.2
ICD-10 Finland
Cervicalgia
2.7
6.4
42
164
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.1
6.4
70
349
M47.82
ICD-10 Finland
Other spondylosis, cervical region
3.6
6.4
27
78
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.3
6.4
22
53
K02.1
ICD-10 Finland
Caries of dentine
1.5
6.3
335
2663
AN1
HP
Coronary angiography
2.1
6.3
70
353
Z01.9
ICD-10 Finland
Special examination, unspecified
2.8
6.3
38
141
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.4
6.3
21
49
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.9
6.3
36
128
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
+∞
6.3
6
*
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
+∞
6.3
6
*
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
6.2
311
2437
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
7.1
6.2
14
20
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.2
176
1208
SPAT1254
SPAT
Administration of medicine
2.0
6.2
79
419
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.2
136
870
M54.6
ICD-10 Finland
Pain in thoracic spine
2.8
6.2
38
143
H02AB04
ATC
methylprednisolone; systemic
1.9
6.2
87
482
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.7
6.2
40
154
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
4.3
6.2
21
50
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.6
6.1
43
173
J01FA06
ATC
roxithromycin; oral
1.5
6.1
240
1781
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
2.2
6.1
62
301
M77.4
ICD-10 Finland
Metatarsalgia
3.4
6.1
27
81
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.1
95
543
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.1
69
352
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
6.1
342
2746
M54
ICD-10 Finland
Dorsalgia
2.1
6.1
66
328
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.7
6.1
40
156
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
8.7
6.1
12
14
Z00.0
ICD-10 Finland
General medical examination
1.8
6.0
105
625
I49.5
ICD-10 Finland
Sick sinus syndrome
3.9
6.0
23
61

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
216
782
3.44
47.69
2.3
2.1
—
—
—
0
0
73
109
7.29
47.45
1.7
1.7
20154.4
15186.0
e6/l
0.22
53
82
48
69
7.35
32.12
1.4
1.5
—
—
—
0
0
50
79
6.70
30.68
1.9
1.5
—
—
—
0
0
272
1519
2.22
23.05
2.7
2.7
1526.8
9052.8
umol/l
3.89
236
1320
274
1562
2.17
21.82
4.6
4.3
—
—
—
0
0
146
650
2.54
20.56
2.0
1.6
—
—
—
0
0
572
4374
2.18
19.90
5.6
3.6
12.8
11.9
mm/h
0.67
539
4015
166
823
2.29
18.23
1.3
1.2
19.1
13.0
u/ml
0.42
70
318
21
23
9.36
17.38
2.1
1.4
—
—
—
0
0
304
1945
1.93
16.61
7.5
5.5
—
—
—
0
0
166
865
2.17
15.96
1.4
1.2
32.7
32.0
iu/ml
0.03
53
279
28
52
5.55
14.57
2.3
1.5
51.4
56.8
%
0.26
19
37
26
45
5.94
14.54
1.7
1.3
73932.8
7084.4
e6/l
0.61
21
29
385
2737
1.81
14.47
4.8
4.0
—
—
—
0
0
260
1654
1.86
13.94
2.6
2.0
156.2
304.6
u/l
1.66
240
1540
406
2961
1.78
13.75
8.1
5.5
0.0
0.0
e9/l
1.62
364
2551
138
707
2.16
13.70
1.4
1.3
375.8
547.2
titre
0.88
38
137
207
1230
1.93
13.65
1.9
1.6
1.1
1.2
mg/l
0.48
156
926
377
2701
1.77
13.48
8.2
5.8
0.7
0.7
%
0.01
355
2523
403
2945
1.77
13.44
8.0
5.5
0.6
0.6
e9/l
1.05
361
2533
414
3050
1.77
13.41
8.5
5.9
0.2
0.2
e9/l
0.97
372
2681
574
4680
1.88
12.98
8.7
7.5
80.3
78.1
u/l
0.48
550
4407
408
3016
1.75
12.86
8.1
5.6
2.0
1.9
e9/l
0.35
367
2645
394
2889
1.74
12.74
8.7
7.1
1.2
1.2
mmol/l
1.56
337
2425
382
2783
1.74
12.59
8.3
5.7
2.9
2.8
%
0.13
361
2595
383
2802
1.73
12.35
8.6
6.1
8.5
8.8
%
1.16
363
2627
338
2391
1.73
12.29
9.8
9.3
1.3
1.3
inr
0.02
101
719
384
2822
1.72
12.10
8.0
5.6
59.2
57.2
%
2.93
364
2651
451
3473
1.72
11.88
9.9
9.1
4.7
4.1
e9/l
2.20
407
3037
456
3535
1.71
11.60
5.2
4.8
6.9
6.7
mmol/l
0.58
427
3288
386
2866
1.69
11.51
8.4
5.8
25.8
27.9
%
3.68
365
2678
700
6198
2.35
11.47
20.5
12.9
22.8
25.2
mg/l
1.13
608
4785
509
4080
1.72
11.30
5.4
3.8
—
—
—
0
0
387
2907
1.66
10.79
4.3
3.2
0.0
0.0
estimate
0.00
70
511
382
2867
1.66
10.64
5.6
4.4
0.0
0.0
estimate
0.50
75
536
355
2617
1.66
10.59
6.5
6.2
1.2
1.2
mmol/l
0.46
315
2368
323
2326
1.67
10.54
2.1
1.9
98.5
94.7
pmol/l
0.73
177
1226
20
37
5.52
10.44
2.3
1.3
28.4
28.6
%
0.01
13
23
214
1387
1.75
10.26
2.4
2.3
—
—
—
0
0
380
2872
1.63
10.12
4.3
3.2
0.0
0.0
estimate
0.00
66
525
549
4555
1.71
10.10
4.6
3.7
14.8
14.8
pmol/l
0.04
504
4111
168
1023
1.82
9.91
1.8
1.7
1196.8
1182.1
nmol/l
0.07
117
757
265
1849
1.66
9.56
2.5
2.3
—
—
—
0
0
640
5578
1.85
9.54
5.3
4.4
1.9
1.9
mu/l
0.12
598
5073
303
2210
1.61
9.03
4.1
3.3
41.7
36.6
ng/l
0.31
222
1515
125
720
1.88
8.74
21.7
22.2
1.3
1.2
inr
0.23
21
105
207
1386
1.67
8.60
2.7
2.0
3.0
3.0
mg/l
0.02
174
1156
396
3102
1.57
8.54
5.5
6.7
12.2
11.7
umol/l
0.17
369
2961
88
453
2.06
8.50
2.1
2.5
10.4
10.7
g/l
0.41
80
412
254
1796
1.62
8.49
2.8
2.5
54.9
58.3
u/l
0.44
235
1670
64
291
2.31
8.41
1.3
1.2
—
—
—
0
0
334
2533
1.56
8.21
6.1
5.1
34.8
35.7
g/l
1.77
309
2366
54
232
2.43
8.06
1.3
1.5
—
10.6
—
0
7
712
6518
2.15
7.95
21.5
15.1
4.0
4.0
mmol/l
0.25
703
6326
230
1624
1.59
7.59
4.2
2.8
—
—
—
0
0
352
2739
1.52
7.49
11.6
9.0
0.1
0.0
e9/l
0.50
295
2245
708
6497
2.05
7.39
21.2
14.9
139.5
139.7
mmol/l
0.78
698
6315
323
2477
1.52
7.30
3.4
2.6
117.0
146.9
ug/l
2.09
295
2280
179
1203
1.63
7.19
1.2
1.2
1.3
1.8
u/ml
0.35
44
324
50
221
2.35
7.03
1.9
1.7
—
—
—
0
0
678
6155
1.82
7.02
4.7
4.3
5.9
5.9
mmol/l
0.08
617
5614
141
896
1.70
7.00
1.9
2.0
29.9
29.7
s
0.12
135
864
711
6561
2.03
6.88
18.3
12.3
—
—
—
0
0
138
880
1.69
6.76
3.6
2.6
12.1
13.7
umol/l
1.75
122
816
176
1201
1.60
6.59
3.4
2.4
4.1
5.6
e6/l
0.83
155
1056
238
1740
1.53
6.58
4.9
4.0
7.4
7.4
ph
0.67
39
330
224
1619
1.54
6.52
2.6
3.0
2320.4
1340.1
ng/l
0.98
194
1383
14
29
4.90
6.47
1.5
1.3
3.9
5.4
u/l
2.04
14
22
69
363
1.99
6.29
1.5
2.3
—
—
—
0
0
272
2068
1.49
6.16
4.8
3.3
88.5
81.3
e6/l
0.07
212
1457
187
1313
1.56
6.15
1.6
1.5
20.2
20.5
nmol/l
0.09
165
1121
128
820
1.67
6.13
3.7
2.5
2.3
2.3
g/l
0.37
114
760
178
1240
1.57
6.06
4.6
3.6
1.0
1.0
kg/l
0.21
23
181
111
687
1.72
6.04
1.4
1.4
—
—
—
0
0
211
1530
1.52
5.98
5.0
3.6
0.0
0.0
estimate
0.80
70
513
110
685
1.71
5.85
5.2
8.7
1.1
1.2
mmol/l
0.12
79
539
106
655
1.72
5.80
2.2
2.4
105.3
147.8
ug/g
1.42
84
526
30
114
2.70
5.79
1.3
1.2
14.8
4.4
e6/l
0.55
25
86
30
114
2.70
5.79
1.4
1.3
188.1
211.5
e6/l
0.07
25
91
119
766
1.65
5.58
9.3
6.6
1.1
1.0
mmol/l
0.46
112
712
78
446
1.83
5.55
5.1
4.2
0.6
0.1
%
0.42
15
116
298
2343
1.44
5.54
2.0
2.0
—
—
—
0
0
696
6456
1.77
5.50
5.2
4.7
2.7
2.8
mmol/l
0.74
642
5963
217
1608
1.49
5.47
3.7
2.8
—
—
—
0
0
720
6759
1.94
5.31
13.3
9.8
28.0
27.5
u/l
0.32
703
6508
101
631
1.69
5.30
1.7
1.7
—
—
—
0
0
107
679
1.67
5.30
5.3
8.7
11.8
12.2
kpa
0.36
96
648
107
679
1.67
5.30
5.3
8.7
5.0
5.1
kpa
0.79
97
645
77
447
1.80
5.22
2.8
2.6
65.9
66.8
g/l
0.43
68
410
78
455
1.79
5.21
4.5
3.3
—
—
—
0
0
18
54
3.39
5.19
1.6
1.4
—
—
—
0
0
98
611
1.69
5.19
2.7
2.6
1.7
1.7
%
0.04
87
550
36
159
2.33
5.12
1.7
1.7
37.8
37.1
g/l
0.23
26
139
78
464
1.76
4.88
5.2
4.2
0.2
0.1
%
0.27
16
133
76
449
1.77
4.87
4.4
4.0
0.8
0.5
%
0.26
13
110
14
37
3.84
4.83
1.1
1.0
49.3
40.1
mg/l
—
9
29
177
1289
1.48
4.80
4.4
3.3
—
—
—
0
0
683
6351
1.64
4.73
4.8
4.3
4.6
4.7
mmol/l
0.41
636
5911
13
33
3.99
4.72
1.2
1.2
—
—
—
0
0
159
1137
1.50
4.71
3.4
2.5
528.6
568.2
mosm/kgh2o
1.26
137
970
76
454
1.75
4.69
3.1
2.8
69.0
68.3
e9/l
0.06
65
351
115
768
1.58
4.64
3.9
2.6
20.9
23.8
%
1.62
91
652
743
7090
2.20
4.62
28.7
18.9
256.3
248.6
e9/l
2.37
734
6886
81
495
1.71
4.62
5.1
4.1
1.4
0.9
%
0.32
16
146
230
1772
1.42
4.62
4.3
2.9
45.9
105.0
e6/l
0.82
191
1361
743
7092
2.19
4.59
28.6
18.8
91.3
91.1
fl
0.86
738
6969
743
7093
2.19
4.57
28.6
18.8
30.4
30.4
pg
0.20
738
6968
63
359
1.82
4.56
3.9
3.5
7.4
7.4
ph
—
10
50
743
7094
2.18
4.55
28.7
18.9
4.5
4.5
e12/l
0.15
735
6872
743
7095
2.18
4.53
28.7
18.9
7.1
6.7
e9/l
3.89
734
6872
743
7096
2.18
4.51
28.8
19.0
136.6
137.1
g/l
0.41
738
6970
94
604
1.63
4.44
5.7
9.3
94.9
95.6
%
0.39
86
579
199
1503
1.44
4.43
4.4
3.8
90.9
89.8
%
0.24
190
1468
33
150
2.25
4.43
1.3
1.2
—
—
—
0
0
80
495
1.69
4.37
2.8
2.9
107.2
186.8
ng/l
2.60
71
447
87
551
1.65
4.35
4.3
3.5
1.8
2.2
mmol/l
0.43
71
428
678
6321
1.59
4.32
4.7
4.2
1.4
1.4
mmol/l
1.56
630
5843
158
1148
1.47
4.30
4.3
3.5
324.6
532.5
ng/l
0.54
127
916
72
436
1.72
4.25
6.7
4.0
109.6
86.3
ng/l
1.00
64
386
25
102
2.50
4.25
1.4
1.3
—
—
—
0
0
88
563
1.64
4.23
4.1
3.5
—
7.4
—
0
5
153
1109
1.47
4.21
1.3
1.4
2.8
2.5
g/l
1.01
95
709
114
777
1.55
4.20
1.3
1.2
—
—
—
0
0
219
1700
1.40
4.15
4.7
3.5
—
—
—
0
0
209
1614
1.40
4.07
4.1
2.8
0.2
0.6
e6/l
4.28
165
1210
33
156
2.17
4.05
1.4
1.3
8.6
8.1
u/l
0.09
28
125
15
48
3.17
3.94
1.4
1.2
—
—
—
0
0
68
416
1.70
3.89
1.4
1.4
—
—
—
0
0
49
272
1.86
3.88
3.7
3.2
—
—
—
0
0
26
114
2.33
3.82
4.5
3.9
—
—
—
0
0
114
794
1.51
3.81
1.6
1.6
—
—
—
0
0
135
979
1.46
3.69
1.8
1.8
—
—
—
0
0
98
665
1.54
3.69
1.4
1.3
—
—
—
0
0
57
337
1.75
3.69
2.6
2.6
—
—
—
0
0
214
1686
1.37
3.65
1.6
1.6
1.4
1.4
mmol/l
0.40
178
1413
655
6112
1.47
3.62
4.3
3.8
1.4
1.3
mmol/l
2.44
607
5628
237
1901
1.36
3.60
5.1
4.0
16.9
8.4
mg/mmol
1.03
163
1228
200
1563
1.38
3.58
3.7
2.8
—
—
—
0
0
6
6
10.06
3.50
3.8
1.5
254.2
167.0
ng/l
—
6
6
35
181
1.98
3.44
1.9
3.0
40.8
36.5
mg/l
0.25
27
144
35
181
1.98
3.44
1.9
3.0
44.3
54.3
mg/l
0.45
27
141
45
254
1.82
3.41
3.2
3.6
—
—
—
0
0
85
571
1.55
3.36
5.9
9.5
124.1
123.1
g/l
0.18
77
545
191
1497
1.37
3.34
7.5
6.8
—
—
—
0
0
23
102
2.29
3.32
2.0
2.1
—
—
—
0
0
34
177
1.96
3.29
1.9
3.0
1.1
1.2
ratio
—
5
12
15
54
2.81
3.27
1.3
1.3
—
—
—
0
0
28
136
2.10
3.26
1.5
3.3
—
—
—
0
0
223
1796
1.34
3.26
3.9
3.2
877.8
297.0
mg/l
0.65
158
1154
83
561
1.54
3.20
2.4
2.1
13.1
13.6
nmol/l
0.21
73
502
96
671
1.49
3.16
3.1
2.8
8.2
8.8
umol/l
0.10
80
589
65
416
1.61
3.16
1.1
1.2
—
—
—
0
0
24
111
2.20
3.15
4.9
3.2
62.0
57.4
%
0.72
24
111
235
1915
1.33
3.15
4.5
3.2
7.3
8.0
mmol/l
1.48
199
1626
130
965
1.42
3.13
3.3
3.7
0.8
0.8
mmol/l
0.33
119
910
163
1259
1.37
3.11
1.9
1.7
385.5
22526352.5
pmol/l
0.99
134
1061
14
50
2.83
3.10
1.4
1.3
—
—
—
0
0
11
34
3.27
3.06
1.4
1.3
—
—
—
0
0
125
927
1.42
3.02
3.5
2.7
2.2
2.2
e6/l
0.02
79
513
172
1350
1.35
2.95
5.8
4.4
—
—
—
0
0
75
506
1.53
2.92
6.6
8.8
—
—
—
0
0
21
95
2.24
2.92
1.2
1.3
—
—
—
0
0
573
5292
1.32
2.86
24.1
15.9
13.7
13.7
%
0.28
561
5159
55
349
1.62
2.79
1.3
1.2
—
—
—
0
0
21
97
2.20
2.79
1.9
1.2
—
—
—
0
0
495
4493
1.28
2.77
4.2
3.6
—
—
—
0
0
33
182
1.85
2.73
1.1
1.1
—
—
—
0
0
22
105
2.13
2.71
4.9
3.0
5.2
4.2
e9/l
0.89
22
105
12
43
2.82
2.65
1.2
1.1
74.0
280.0
titre
—
5
6
76
526
1.49
2.65
6.2
4.5
—
—
—
0
0
23
113
2.07
2.64
5.1
4.8
2.3
2.2
mmol/l
0.06
15
67
59
387
1.57
2.62
5.8
7.9
25.0
24.4
mmol/l
0.50
51
358
72
500
1.49
2.48
2.7
2.3
9.2
8.6
ug/l
0.07
59
443
24
123
1.98
2.47
2.2
2.8
—
—
—
0
0
12
45
2.69
2.46
1.1
1.0
—
—
—
0
0
39
235
1.69
2.43
3.0
2.9
—
—
—
0
0
285
2452
1.26
2.40
4.8
4.5
1.9
2.9
ug/l
1.53
269
2195
83
597
1.44
2.40
1.4
1.5
—
—
—
0
0
41
253
1.66
2.35
2.6
2.1
5.5
1.3
ug/l
0.75
35
222
39
238
1.67
2.33
1.6
1.8
1.6
1.6
g/l
0.09
31
203
17
78
2.21
2.32
1.4
1.3
263.9
290.9
pmol/l
0.21
12
66
10
35
2.88
2.31
1.0
1.3
0.0
1.4
u/ml
—
5
19
34
201
1.72
2.28
1.5
1.7
—
—
—
0
0
58
394
1.51
2.24
4.2
6.1
—
—
—
0
0
620
5854
1.30
2.20
6.7
5.5
40.2
39.7
mmol/mol
0.70
575
5433
35
211
1.69
2.20
4.2
8.6
1.2
1.4
mmol/l
0.78
29
185
18
87
2.09
2.18
1.3
1.9
1.3
0.9
g/l
0.42
12
64
12
49
2.47
2.11
1.4
1.3
7.7
7.1
g/l
—
6
30
12
49
2.47
2.11
1.4
1.3
2.8
2.7
g/l
—
6
29
12
49
2.47
2.11
1.4
1.3
0.3
0.3
g/l
—
6
29
17
82
2.10
2.08
1.1
1.2
—
—
—
0
0
6
15
4.02
2.04
1.0
1.1
—
—
—
0
0
227
1938
1.24
1.99
2.8
3.7
2.3
2.4
mmol/l
0.34
192
1710
21
114
1.87
1.88
2.6
2.7
17.5
16.7
%
0.39
13
64
54
376
1.47
1.88
3.3
3.8
4.7
4.2
e9/l
0.69
41
297
49
335
1.49
1.87
6.7
12.7
—
—
—
0
0
39
256
1.55
1.79
3.8
7.5
1.7
1.7
%
0.15
34
239
20
109
1.86
1.78
1.5
1.8
—
—
—
0
0
55
390
1.44
1.76
1.4
1.2
121.5
139.3
iu/ml
0.25
27
153
10
41
2.46
1.76
2.8
1.8
11.5
11.5
%
—
10
41
15
74
2.05
1.76
11.3
2.8
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
633.2
ng/l
—
0
6
98
767
1.32
1.73
1.2
1.3
—
—
—
0
0
13
61
2.15
1.72
1.0
1.1
—
—
—
0
0
26
157
1.68
1.67
3.5
3.1
—
—
—
0
0
65
483
1.38
1.62
5.0
3.9
1.2
1.2
mmol/l
0.88
51
414
12
56
2.16
1.61
1.0
1.2
—
—
—
0
0
18
99
1.84
1.58
1.1
1.1
—
—
—
0
0
37
250
1.50
1.53
3.9
7.5
0.9
0.9
%
0.21
32
233
13
65
2.02
1.49
2.4
1.2
—
—
—
0
0
24
147
1.65
1.49
7.3
2.0
—
—
—
0
0
50
363
1.40
1.44
3.5
2.8
127.0
131.5
g/l
0.66
50
354
6
22
2.74
1.43
1.0
1.1
256.1
286.9
iu/ml
—
6
22
612
5856
1.22
1.42
20.3
13.9
40.7
40.3
%
0.44
417
4262
27
173
1.58
1.42
6.8
1.9
—
—
—
0
0
21
126
1.69
1.41
3.0
2.1
24.9
1203.0
u/l
—
6
51
20
119
1.70
1.39
2.1
2.3
137.9
132.6
g/l
0.40
14
93
49
656
0.73
1.34
1.2
1.4
—
—
—
0
0
23
144
1.62
1.33
1.3
1.1
—
—
—
0
0
55
415
1.35
1.28
1.5
1.5
—
—
—
0
0
28
186
1.52
1.28
6.6
1.8
—
—
—
0
0
11
55
2.01
1.28
1.3
2.8
—
—
—
0
0
28
187
1.52
1.25
6.7
1.8
—
—
—
0
0
20
124
1.63
1.21
1.3
1.6
—
—
—
0
0
5
19
2.64
1.21
1.6
3.4
—
—
—
0
0
8
38
2.12
1.18
1.0
1.7
—
—
—
0
0
14
79
1.79
1.17
1.2
1.2
2.3
4.8
u/ml
—
7
28
17
102
1.68
1.17
1.1
1.1
—
—
—
0
0
24
158
1.54
1.16
1.3
1.5
279.6
293.7
ug/g
0.13
16
89
15
87
1.74
1.15
6.1
4.0
—
—
—
0
0
15
87
1.74
1.15
1.6
4.1
1.3
0.9
%
—
10
73
13
72
1.82
1.15
1.0
1.3
—
—
—
0
0
14
80
1.76
1.13
2.2
2.4
—
—
—
0
0
23
151
1.54
1.12
1.5
1.9
285.1
4.7
iu/l
0.46
11
56
11
58
1.91
1.12
2.2
2.4
—
—
—
0
0
11
58
1.91
1.12
1.2
1.4
—
—
—
0
0
24
160
1.52
1.10
4.0
3.7
—
—
—
0
0
5
21
2.39
1.09
1.2
1.7
—
—
—
0
0
7
32
2.20
1.08
1.9
1.9
—
—
—
0
0
70
562
1.27
1.08
1.9
2.3
0.2
0.2
g/l
0.20
61
529
27
186
1.47
1.07
6.8
1.8
—
—
—
0
0
7
33
2.13
1.05
1.1
1.2
179.9
143.9
nmol/l
—
7
33
12
67
1.80
1.05
1.0
1.1
—
—
—
0
0
64
511
1.28
1.04
5.2
3.3
—
—
—
0
0
9
46
1.97
1.04
1.6
1.2
—
—
—
0
0
31
222
1.41
1.02
1.5
1.3
27.5
27.9
iu/l
0.02
26
187
14
83
1.70
1.02
1.1
1.3
—
0.6
—
0
7
17
107
1.60
1.00
1.4
1.2
—
—
—
0
0
5
23
2.18
0.98
1.6
12.9
—
—
—
0
0
0
30
0.00
0.97
0.0
1.5
—
—
—
0
0
6
27
2.23
0.93
3.7
2.1
—
—
—
0
0
10
55
1.83
0.92
1.3
1.2
—
—
—
0
0
13
78
1.68
0.92
1.2
1.3
—
—
—
0
0
11
63
1.76
0.90
1.4
4.7
—
—
—
0
0
6
29
2.08
0.89
1.0
1.0
—
—
—
0
0
6
30
2.01
0.87
26.3
28.4
6.9
7.3
ug/l
—
6
25
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
30
223
1.36
0.83
1.2
1.1
—
—
—
0
0
18
122
1.49
0.80
1.8
1.5
—
—
—
0
0
37
288
1.30
0.77
2.7
2.3
—
—
—
0
0
16
107
1.51
0.76
3.4
3.1
0.8
0.9
nmol/l
0.27
11
83
19
132
1.45
0.76
3.6
2.8
1.5
1.6
mmol/l
0.20
19
127
14
91
1.55
0.75
1.2
1.3
—
—
—
0
0
5
25
2.01
0.72
1.6
4.5
—
—
—
0
0
9
56
1.61
0.72
2.4
2.4
—
—
—
0
0
21
151
1.40
0.72
4.4
10.4
11.6
11.5
mmol/l
0.03
16
135
21
151
1.40
0.72
4.4
10.4
104.8
104.9
mmol/l
0.06
16
135
25
186
1.36
0.71
1.3
1.7
—
—
—
0
0
5
26
1.93
0.70
1.0
2.2
—
—
—
0
0
7
42
1.67
0.68
1.4
1.9
—
—
—
0
0
57
678
0.83
0.68
1.5
1.6
—
—
—
0
0
12
78
1.55
0.66
1.2
1.2
—
—
—
0
0
17
120
1.43
0.65
2.4
2.7
—
—
—
0
0
5
30
1.67
0.61
1.0
4.1
—
—
—
0
0
16
113
1.42
0.61
1.8
1.4
113.2
109.6
u/ml
—
6
17
14
97
1.45
0.59
6.4
5.3
292.2
377.4
umol/l
1.56
14
81
75
653
1.16
0.58
2.8
4.7
8.8
34.5
ug/l
1.14
59
528
11
73
1.51
0.56
2.1
3.1
—
—
—
0
0
11
73
1.51
0.56
2.6
2.6
—
—
—
0
0
8
55
1.46
0.56
1.1
1.1
1.2
1.4
nmol/l
—
8
50
14
99
1.42
0.54
1.0
1.1
1.3
1.5
g/l
1.80
14
88
10
66
1.52
0.52
2.2
2.0
90.5
89.3
%
—
10
66
10
67
1.50
0.50
1.1
1.1
—
—
—
0
0
11
76
1.45
0.48
1.0
1.0
5.6
2.5
u/ml
—
5
28
20
155
1.30
0.47
2.7
2.3
103.5
107.7
ug/min
—
10
89
27
218
1.25
0.47
3.4
4.1
—
—
—
0
0
24
191
1.26
0.47
6.5
8.7
—
—
—
0
0
64
563
1.15
0.46
1.3
1.4
—
—
—
0
0
7
49
1.43
0.46
1.6
2.2
—
33.0
—
0
7
10
69
1.46
0.44
1.0
1.0
2.6
2.2
u/ml
—
5
25
7
51
1.38
0.44
1.0
1.1
—
—
—
0
0
13
95
1.37
0.44
1.1
1.1
5.2
3.0
u/ml
—
5
36
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
8
58
1.38
0.41
2.4
3.2
—
—
—
0
0
5
33
1.52
0.41
1.4
2.7
529.6
1573.7
u/ml
—
5
33
0
17
0.00
0.40
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
12
89
1.35
0.38
1.1
2.7
414.4
144.2
u/ml
0.26
12
83
27
322
0.83
0.38
1.6
1.7
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
153
1435
1.08
0.37
3.1
2.8
0.6
0.7
ug/l
2.72
102
910
26
217
1.21
0.36
4.0
3.9
0.2
0.2
g/l
0.04
17
97
5
76
0.66
0.36
1.2
1.7
—
—
—
0
0
5
76
0.66
0.36
1.2
1.7
—
—
—
0
0
5
76
0.66
0.36
1.2
1.7
—
—
—
0
0
5
76
0.66
0.36
1.2
1.7
—
—
—
0
0
10
73
1.37
0.34
5.1
3.1
13.4
13.1
%
—
10
73
11
82
1.35
0.34
1.1
1.0
1.1
4.5
u/ml
—
5
19
11
82
1.35
0.34
3.2
2.2
31.7
32.7
pg
0.37
11
82
16
127
1.27
0.33
13.9
3.0
—
—
—
0
0
6
88
0.68
0.33
1.5
1.6
—
—
—
0
0
11
84
1.31
0.30
2.2
1.9
1.5
1.6
mmol/l
0.19
11
84
8
63
1.27
0.28
1.0
1.3
—
—
—
0
0
19
159
1.20
0.27
1.1
1.2
—
—
—
0
0
10
77
1.30
0.26
1.1
1.3
—
—
—
0
0
5
72
0.69
0.26
1.2
1.3
—
—
—
0
0
5
73
0.68
0.26
2.4
2.5
—
—
—
0
0
5
73
0.68
0.26
1.0
1.1
—
—
—
0
0
11
138
0.79
0.25
2.5
3.6
21.2
28.0
mg/l
—
6
85
6
85
0.70
0.24
1.3
1.5
—
—
—
0
0
6
85
0.70
0.24
1.3
1.5
—
—
—
0
0
18
152
1.19
0.24
2.1
1.5
—
—
—
0
0
10
125
0.80
0.23
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
17.4
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
16
184
0.87
0.17
1.7
1.1
—
—
—
0
0
14
162
0.86
0.16
1.6
1.3
127.2
235.8
miu/ml
—
8
67
6
76
0.79
0.15
1.8
3.4
14.3
5.4
nmol/l
—
6
76
9
107
0.84
0.13
1.0
1.1
—
—
—
0
0
9
108
0.83
0.13
1.0
1.1
—
—
—
0
0
243
2477
0.97
0.12
3.2
2.8
—
—
—
0
0
28
261
1.08
0.10
1.0
1.1
—
80.7
titre
—
0
9
38
402
0.94
0.10
1.3
1.4
—
—
—
0
0
5
44
1.14
0.10
4.8
4.9
—
53.1
—
0
17
7
65
1.08
0.08
2.6
1.8
—
—
—
0
0
54
521
1.04
0.07
1.4
1.4
—
—
—
0
0
177
1749
1.02
0.05
1.5
1.4
—
—
—
0
0
28
273
1.03
0.01
1.0
1.1
—
—
—
0
0
106
1054
1.01
0.00
2.6
3.2
2.5
2.4
mmol/l
0.62
93
935
12
116
1.04
0.00
1.2
1.1
17.4
13.5
iu/ml
—
5
25
19
186
1.02
0.00
1.1
1.1
—
—
—
0
0
47
465
1.01
0.00
1.6
1.7
—
—
—
0
0
12
122
0.98
0.00
1.8
1.1
410.3
248.7
u/ml
—
6
75
12
122
0.98
0.00
1.8
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
143.8
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
8
88
0.91
0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
7.4
—
—
—
0
0
6
68
0.88
0.00
1.3
1.4
0.2
0.3
nmol/l
—
6
56
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
6
62
0.97
0.00
2.2
9.1
6.7
6.9
mmol/l
—
6
54
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_SYNOTENDINOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_SYNOTENDINOTH 1.148 [0.98, 1.35] 0.091
Birth year 0.994 [0.99, 1.0] 0.143

During the follow-up period (1.1.1998 — 31.12.2019), 339 out of 2095 females with M13_SYNOTENDINOTH died.

Males

Parameter HR [95% CI] p-value
M13_SYNOTENDINOTH 1.269 [1.11, 1.45] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 486 out of 2633 males with M13_SYNOTENDINOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_SYNOTENDINOTH.

N-year risk Females Males
1 0.1% 0.256%
5 0.619% 1.539%
10 1.6% 3.883%
15 3.072% 7.347%
20 5.635% 11.901%

Relationships between endpoints

Index endpoint: M13_SYNOTENDINOTH – Disorders of synovium and tendon in diseases classified elsewhere

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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