Livedoid vasculitis

L12_LIVEDOIDVASC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L95.0
  • Cause of death: ICD-10 L95.0

2 out of 7 registries used, show all original rules.

137

4. Check minimum number of events

None

137

5. Include endpoints

None

137

6. Filter based on genotype QC (FinnGen only)

129

Control definitions (FinnGen only)

Control exclude
L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L95
Name in latin
Vasculitis lividoides

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 736 442 289
Only index persons 645 394 251
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 62.30 64.34 59.28
Only index persons 60.70 62.60 57.71

-FinnGen-

Key figures

All Female Male
Number of individuals 129 80 49
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 63.49 65.33 60.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
137
Matched controls
1370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L95.0
ICD-10 Finland
Livedoid vasculitis
+∞
197.9
137
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
18.7
64.4
66
65
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
165.2
58.4
58
6
S97
ICPC
Chronic ulcer skin
18.3
56.1
54
47
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
28.3
53.3
39
19
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
720.7
52.1
48
*
L95.8
ICD-10 Finland
Other vasculitis limited to skin
+∞
37.2
34
*
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
66.4
31.1
35
7
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
174.3
27.8
28
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
11.5
26.7
31
34
A46
ICD-10 Finland
Erysipelas
6.6
24.0
52
117
H02AB06
ATC
prednisolone; systemic
5.8
19.7
104
481
SPAT1148
SPAT
Treatment of chronic ulcer or burn
5.7
19.4
47
115
D69.0
ICD-10 Finland
Allergic purpura
218.7
19.0
19
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
6.3
18.6
38
79
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
7.2
17.3
29
49
J01FF01
ATC
clindamycin; systemic
4.5
17.0
71
266
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
179.7
15.8
16
*
D07AC01
ATC
betamethasone; topical
4.1
15.2
78
333
L04AX01
ATC
azathioprine; systemic
12.6
15.1
27
26
I83.2
ICD-10 Finland
Varicose veins of lower extremities with both ulcer and inflammation
167.1
14.8
15
*
ZZA00
NOMESCO Finland
Split skin graft
23.1
14.3
20
10
J01MA02
ATC
ciprofloxacin; systemic
3.8
13.5
82
384
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.2
13.3
46
146
D07AD01
ATC
clobetasol; topical
4.3
13.2
44
136
E0000UV, ,
ATC
3.6
12.3
82
400
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.6
12.2
34
91
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
5.9
11.7
23
45
H02AB07
ATC
prednisone; oral
4.2
11.6
37
110
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
22.4
11.4
16
8
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.9
10.9
27
65
J01CF05
ATC
flucloxacillin; systemic
5.6
10.7
22
45
R60.0
ICD-10 Finland
Localized oedema
4.2
10.5
33
96
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
10.4
34
102
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.2
10.4
75
374
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
22.0
10.0
14
7
S76
ICPC
Skin infection other
5.7
9.9
20
40
B01AB05
ATC
enoxaparin; parenteral
3.1
9.8
68
328
S91.0
ICD-10 Finland
Open wound of ankle
59.3
9.8
11
*
L04AX03
ATC
methotrexate; systemic
4.4
9.7
28
76
B01AA03
ATC
warfarin; systemic
3.6
9.7
41
147
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
9.7
89
504
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
23.7
9.5
13
6
TQW80
NOMESCO Finland
Local dermatologic skincare
13.9
9.1
15
12
D09AB01
ATC
zinc bandage without supplements; topical
26.1
9.1
12
5
C03CA01
ATC
furosemide; systemic
3.0
9.0
64
310
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.3
9.0
26
71
N02AX02
ATC
tramadol; systemic, rectal
3.0
8.9
80
440
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.4
8.9
19
40
J01MA12
ATC
levofloxacin; systemic
3.3
8.7
41
156
J04BA02
ATC
dapsone; oral
95.7
8.5
9
*
D07AB08
ATC
desonide; topical
3.9
8.5
28
84
S18
ICPC
Laceration/cut
2.9
8.3
83
477
S21
ICPC
Skin texture symptom/complaint
3.3
8.3
38
142
N02AA05
ATC
oxycodone; systemic
3.1
8.1
43
175
P01BA02
ATC
hydroxychloroquine; oral
4.3
8.0
23
62
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
19.7
7.7
11
6
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
7.7
35
130
L04AD01
ATC
ciclosporin; systemic
14.5
7.5
12
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
7.1
48
222
SPAT1229
SPAT
Assessment of need for aid
4.2
6.9
20
54
C03DA01
ATC
spironolactone; oral
3.3
6.9
29
102
D07AC13
ATC
mometasone; topical
2.7
6.7
51
249
D02AX
ATC
Other emollients and protectives
10.8
6.7
12
12
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
6.6
74
434
N03AX16
ATC
[U] pregabalin
2.7
6.5
45
209
M30.0
ICD-10 Finland
Polyarteritis nodosa
73.1
6.5
7
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
6.4
46
218
A08
ICPC
Swelling
4.4
6.4
17
43
S11
ICPC
Skin infection post-traumatic
19.1
6.4
9
5
J01DB01
ATC
cefalexin; oral
4.0
6.3
123
943
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
9.3
6.2
12
14
J01CF02
ATC
cloxacillin; systemic
10.7
6.2
11
11
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.1
6.2
18
49
K07
ICPC
Swollen ankles/oedema
5.6
6.1
17
34
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
6.1
23
75

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
42
17.05
49.27
1.5
1.1
—
—
—
0
0
59
118
8.03
31.42
4.4
1.4
—
—
—
0
0
56
151
5.58
20.88
1.6
1.4
686.32
640.00
titre
0.05
19
39
41
110
4.89
14.87
1.5
1.5
—
—
—
0
0
106
567
4.84
14.86
11.4
5.6
0.06
0.04
e9/l
0.67
93
495
105
566
4.66
14.36
11.5
5.6
0.69
0.58
e9/l
0.84
92
494
106
580
4.66
14.08
11.6
5.6
1.82
1.81
e9/l
0.04
94
521
107
591
4.70
13.99
11.6
5.6
0.20
0.18
e9/l
0.31
95
524
34
86
4.93
13.12
2.7
2.9
—
—
—
0
0
99
545
3.94
12.34
11.8
5.8
—
—
—
0
0
47
165
3.81
11.64
2.5
1.8
31.39
29.56
s
1.06
47
160
110
678
4.16
10.96
15.9
9.0
4.87
4.28
e9/l
0.51
100
596
30
79
4.58
10.91
1.3
1.4
—
—
—
0
0
59
251
3.37
10.74
1.9
1.6
0.98
1.47
mg/l
1.19
50
198
70
332
3.27
10.61
6.6
4.3
—
—
—
0
0
46
173
3.50
10.11
3.4
2.1
—
—
—
0
0
39
135
3.64
9.69
1.5
1.5
—
—
—
0
0
59
288
2.84
8.02
9.8
6.9
—
—
—
0
0
41
166
3.10
7.78
1.6
1.8
—
—
—
0
0
49
222
2.88
7.59
4.5
3.7
101.05
62.73
ng/l
0.24
43
180
94
596
2.84
7.51
8.9
7.0
1.21
1.22
mmol/l
0.23
85
508
80
472
2.67
7.30
2.4
2.0
85.99
98.01
pmol/l
1.69
49
220
53
259
2.71
7.03
3.2
3.7
—
—
—
0
0
85
530
2.59
6.73
23.6
13.0
1.45
1.26
inr
0.57
26
164
27
92
3.41
6.73
2.8
3.3
66.35
70.04
e9/l
0.22
20
70
87
550
2.59
6.67
8.3
6.2
1.21
1.21
mmol/l
0.06
79
502
72
419
2.51
6.55
5.1
4.2
49.67
73.67
e6/l
0.42
52
312
71
420
2.43
6.12
5.2
3.0
2.37
2.36
mmol/l
0.27
62
362
107
779
2.71
5.64
7.7
4.6
—
—
—
0
0
12
17
7.62
5.57
1.4
1.3
—
—
—
0
0
62
357
2.35
5.55
3.6
2.3
—
—
—
0
0
8
5
16.85
5.48
1.3
1.2
16.37
13.00
umol/l
—
8
5
32
137
2.74
5.34
1.7
1.6
—
—
—
0
0
26
102
2.91
5.08
6.2
4.0
—
—
—
0
0
30
133
2.61
4.64
3.3
2.6
7.02
7.80
umol/l
0.16
25
117
53
304
2.21
4.62
3.7
2.7
356.30
7916.99
umol/l
1.99
47
259
11
20
5.88
4.39
1.7
1.6
—
—
—
0
0
62
387
2.10
4.29
5.5
3.7
7.38
7.40
ph
—
6
71
39
203
2.29
4.25
3.1
3.2
2.41
2.36
e6/l
0.02
22
110
11
21
5.60
4.24
1.3
1.0
—
—
—
0
0
60
374
2.08
4.14
4.7
3.4
28.25
42.30
e6/l
0.39
48
289
75
511
2.03
4.02
15.5
9.3
0.00
0.00
e9/l
0.71
61
412
28
129
2.47
3.98
1.4
1.2
—
—
—
0
0
50
298
2.07
3.84
1.7
1.6
21.54
21.81
nmol/l
0.04
42
248
67
445
1.99
3.80
2.8
2.0
—
—
—
0
0
39
215
2.14
3.65
1.3
1.3
33.69
29.91
iu/ml
—
10
72
11
26
4.51
3.59
1.2
1.4
—
—
—
0
0
58
372
1.97
3.59
3.3
2.6
50.64
55.77
u/l
1.01
53
347
8
13
6.46
3.55
1.0
1.0
—
—
—
0
0
53
340
1.91
3.21
4.6
3.1
—
—
—
0
0
23
107
2.38
3.19
5.8
6.7
—
—
—
0
0
6
8
7.78
3.08
1.2
1.3
—
—
—
0
0
39
228
1.99
3.08
2.2
1.5
3.40
2.73
g/l
0.47
27
132
5
5
10.31
3.00
1.2
1.0
—
—
—
0
0
53
348
1.85
2.94
4.8
3.2
0.43
0.36
e6/l
0.10
41
264
21
392
0.45
2.90
2.3
3.0
—
—
—
0
0
34
193
2.01
2.90
1.4
1.3
36.57
12.80
u/ml
0.56
15
71
10
29
3.64
2.75
1.3
2.0
—
—
—
0
0
8
20
4.18
2.61
1.1
1.4
—
—
—
0
0
5
7
7.36
2.57
2.4
1.9
41.70
29.31
%
—
5
7
75
563
1.73
2.56
3.6
3.8
0.00
0.00
estimate
—
9
118
56
391
1.73
2.45
4.3
3.4
—
—
—
0
0
7
17
4.28
2.39
1.1
1.0
—
—
—
0
0
19
93
2.21
2.35
1.8
2.4
6.31
6.55
ug/l
0.03
14
83
75
573
1.68
2.32
5.1
5.2
0.00
0.00
estimate
—
9
107
50
347
1.69
2.20
4.3
3.2
6.85
7.39
mmol/l
0.41
45
276
6
14
4.43
2.17
1.2
1.3
—
—
—
0
0
6
14
4.43
2.17
1.7
1.3
—
—
—
0
0
14
62
2.40
2.16
2.6
2.4
—
—
—
0
0
39
254
1.75
2.14
1.2
1.3
1.01
0.92
u/ml
—
8
70
119
1049
2.02
2.09
5.2
4.8
2.16
1.99
mu/l
0.69
109
942
6
15
4.13
2.06
1.2
1.2
—
—
—
0
0
10
39
2.68
1.99
2.7
2.9
—
—
—
0
0
47
331
1.64
1.92
4.2
3.3
36.28
253.54
mg/l
0.58
31
211
49
350
1.62
1.89
5.2
3.9
7.27
9.51
mg/mmol
0.24
32
216
73
581
1.55
1.74
3.7
3.8
0.00
0.00
estimate
—
8
104
5
13
3.95
1.73
2.8
2.0
—
—
—
0
0
125
1139
2.11
1.71
34.5
14.8
28.08
21.78
mg/l
1.41
113
898
37
252
1.64
1.70
3.6
3.1
520.10
516.50
mosm/kgh2o
0.04
30
218
6
19
3.25
1.68
1.3
1.3
—
—
—
0
0
14
70
2.11
1.66
6.8
5.4
24.46
25.05
mmol/l
0.23
14
70
17
92
1.97
1.65
3.8
3.7
—
—
—
0
0
10
44
2.37
1.59
4.9
3.2
—
—
—
0
0
19
109
1.86
1.56
6.1
6.0
1.33
1.26
mmol/l
0.15
19
103
6
21
2.94
1.52
1.8
3.3
—
—
—
0
0
5
16
3.20
1.45
1.0
1.7
—
—
—
0
0
12
60
2.10
1.43
2.7
3.5
0.16
0.09
e6/l
0.37
12
60
17
98
1.84
1.38
1.4
1.3
—
—
—
0
0
0
40
0.00
1.35
0.0
5.5
—
—
—
0
0
99
867
1.51
1.34
4.3
3.9
14.77
14.89
pmol/l
0.18
91
772
9
44
2.12
1.29
1.7
1.8
—
—
—
0
0
9
44
2.12
1.29
1.2
1.1
—
—
—
0
0
24
158
1.63
1.25
5.8
6.0
103.50
103.87
mmol/l
0.12
24
158
15
86
1.84
1.25
1.1
1.3
—
—
—
0
0
5
19
2.69
1.22
1.8
1.8
63.20
59.25
%
—
5
19
11
57
2.01
1.21
1.4
1.3
540.25
180.96
u/ml
0.39
11
49
13
74
1.84
1.11
1.4
1.2
—
—
—
0
0
21
139
1.60
1.08
8.8
10.2
0.29
1.47
mmol/l
0.56
15
116
7
33
2.18
1.07
1.3
1.2
—
—
—
0
0
17
107
1.67
1.05
1.5
1.5
—
—
—
0
0
12
68
1.84
1.04
2.3
3.1
3.92
4.26
pmol/l
0.80
12
62
23
321
0.66
1.01
3.6
3.5
—
—
—
0
0
121
1128
1.62
1.01
5.8
4.7
6.47
6.00
mmol/l
0.57
112
1022
131
1254
2.02
0.99
43.0
21.6
262.05
248.53
e9/l
0.90
125
1222
131
1254
2.02
0.99
43.0
21.7
7.52
6.68
e9/l
1.33
125
1219
24
168
1.52
0.98
1.6
1.2
—
—
—
0
0
11
63
1.81
0.93
14.5
15.9
—
—
—
0
0
6
28
2.19
0.92
2.8
1.3
—
—
—
0
0
8
43
1.91
0.89
1.0
1.2
—
—
—
0
0
6
30
2.04
0.88
2.8
1.3
—
—
—
0
0
6
30
2.04
0.88
2.8
1.3
—
—
—
0
0
131
1255
2.00
0.87
43.6
21.6
39.22
39.91
%
1.01
125
1180
131
1255
2.00
0.87
43.1
21.6
4.27
4.47
e12/l
4.27
125
1217
23
308
0.70
0.81
1.4
1.4
—
—
—
0
0
0
24
0.00
0.80
0.0
3.2
—
107.38
—
0
24
0
24
0.00
0.80
0.0
3.3
—
3.93
—
0
24
113
1055
1.41
0.76
7.4
6.0
41.94
40.07
mmol/mol
1.07
106
971
5
24
2.12
0.75
3.2
2.3
—
—
—
0
0
7
41
1.74
0.71
1.3
1.2
—
—
—
0
0
5
27
1.88
0.69
1.8
3.0
—
—
—
0
0
5
29
1.75
0.64
1.0
2.0
—
4.43
—
0
10
5
29
1.75
0.64
3.2
1.3
—
—
—
0
0
5
29
1.75
0.64
3.0
1.3
—
—
—
0
0
12
81
1.53
0.59
5.8
3.9
0.43
0.31
%
—
7
24
0
23
0.00
0.59
0.0
3.3
—
—
—
0
0
6
35
1.75
0.58
1.0
1.1
—
—
—
0
0
10
65
1.58
0.57
1.8
2.7
1.41
1.18
%
—
10
65
121
1157
1.39
0.55
5.1
5.2
2.47
2.71
mmol/l
2.37
112
1052
9
63
1.46
0.53
1.4
2.7
0.58
0.70
%
—
9
63
18
137
1.36
0.50
1.4
1.3
—
—
—
0
0
7
45
1.58
0.50
1.4
3.5
—
—
—
0
0
5
31
1.64
0.43
7.8
6.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
11
80
1.41
0.40
7.3
9.5
—
—
—
0
0
8
115
0.68
0.39
1.4
1.7
—
—
—
0
0
35
303
1.21
0.38
4.5
4.0
0.00
0.00
estimate
—
9
105
22
181
1.26
0.37
2.5
2.7
0.52
0.74
ug/l
1.53
17
106
5
79
0.62
0.36
2.0
2.9
—
—
—
0
0
6
43
1.41
0.35
2.7
3.1
—
—
—
0
0
11
83
1.35
0.33
1.5
1.3
—
—
—
0
0
6
47
1.29
0.32
11.5
15.2
1.42
0.93
%
—
6
42
7
99
0.69
0.32
9.7
3.9
1.24
1.22
mmol/l
—
7
87
8
106
0.74
0.30
6.4
3.4
—
—
—
0
0
16
132
1.24
0.27
4.8
4.1
2.37
42.34
ug/l
—
10
112
12
96
1.27
0.25
7.4
3.7
0.57
0.59
%
—
7
34
38
346
1.14
0.23
4.8
4.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
116
1185
0.86
0.19
19.0
13.6
—
—
—
0
0
8
72
1.12
0.16
1.0
1.2
—
—
—
0
0
5
47
1.07
0.09
12.8
15.1
1.88
1.57
%
—
5
42
10
88
1.15
0.08
8.0
3.8
0.00
0.00
%
—
5
26
7
68
1.03
0.08
2.6
1.7
—
—
—
0
0
114
1130
1.05
0.03
4.8
4.6
4.36
4.64
mmol/l
2.62
108
1035
47
463
1.02
0.01
4.6
4.0
29.96
47.91
ng/l
0.71
36
340
112
1124
0.98
0.00
4.8
4.6
1.36
1.50
mmol/l
3.31
105
1021
109
1092
0.99
0.00
4.2
4.2
1.27
1.27
mmol/l
0.01
103
989
82
821
1.00
0.00
4.2
3.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
60.00
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
1829.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
89
0.89
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
10.6
12.1
22.95
25.06
mmol/l
—
8
74
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
16.5
—
689.50
—
0
6
0
6
0.00
-0.00
0.0
22.5
—
921.17
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
52.83
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
10.62
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
155.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
35.30
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_LIVEDOIDVASC and mortality.

Females

Parameter HR [95% CI] p-value
L12_LIVEDOIDVASC 2.31 [1.71, 3.12] < 0.001
Birth year 0.992 [0.98, 1.0] 0.057

During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 387 females with L12_LIVEDOIDVASC died.

Males

Parameter HR [95% CI] p-value
L12_LIVEDOIDVASC 2.531 [1.81, 3.53] < 0.001
Birth year 0.988 [0.98, 1.0] 0.037

During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 258 males with L12_LIVEDOIDVASC died.

Mortality risk

Mortality risk for people of age

years, who have L12_LIVEDOIDVASC.

N-year risk Females Males
1 0.23% 0.457%
5 1.255% 2.884%
10 3.34% 7.557%
15 5.871% 13.411%
20 10.136% 22.15%

Relationships between endpoints

Index endpoint: L12_LIVEDOIDVASC – Livedoid vasculitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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