No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1028 |
4. Check minimum number of eventsNone |
1028 |
5. Include endpointsNone |
1028 |
6. Filter based on genotype QC (FinnGen only) |
1000 |
Control definitions (FinnGen only)
- Control exclude
- M13_OSTEOCHONDRO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M80-M85
- Name in latin
- Aliae perturbationes densitatis et structurae ossium
Similar endpoints
↥List of similar endpoints to
Other disorders of bone density and structure
based on the number of shared cases.
Similar with more cases:
- Osteopathies and chondropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8060 | 4419 | 3617 |
| Only index persons | 7643 | 4236 | 3407 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.13 | 0.10 |
| Only index persons | 0.14 | 0.16 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 39.96 | 45.13 | 33.56 |
| Only index persons | 39.69 | 44.77 | 33.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1000 | 647 | 353 |
| Unadjusted period prevalence (%) | 0.21 | 0.23 | 0.16 |
| Median age at first event (years) | 46.08 | 45.78 | 46.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1028
- Matched controls
- 10280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
1112.8
307.7
363
5
M85.4
ICD-10 Finland
Solitary bone cyst
2483.1
203.0
190
*
M85.9
ICD-10 Finland
Disorder of bone density and structure, unspecified
753.8
137.1
132
*
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
30.0
124.0
83
30
M85.6
ICD-10 Finland
Other cyst of bone
1229.0
114.9
110
*
M85.0
ICD-10 Finland
Fibrous dysplasia (monostotic)
+∞
86.7
82
*
9102
FHL
Trepanation or removal of the local bone process
41.9
79.2
48
12
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
16.9
76.7
65
41
M81.9
ICD-10 Finland
Osteoporosis, unspecified
12.2
58.9
60
52
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
10.3
56.8
65
67
M85.5
ICD-10 Finland
Aneurysmal bone cyst
+∞
52.5
50
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
19.2
46.7
37
20
M85.3
ICD-10 Finland
Osteitis condensans
467.6
45.6
45
*
7332X
ICD-9 Finland
Other disorders of bone and cartilage, Cyst of bone[CYSTA OSSIS ALIA]
+∞
37.7
36
*
7332A
ICD-9 Finland
Other disorders of bone and cartilage, Cyst of bone[CYSTA SOLITARIA OSSIS]
+∞
34.6
33
*
M05BA04
ATC
alendronic acid; oral
4.1
34.3
99
258
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
53.2
30.5
36
7
N02AX02
ATC
tramadol; systemic, rectal
2.1
29.4
462
2866
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
7.4
27.3
40
56
M05BA07
ATC
risedronic acid; oral
6.7
26.2
42
65
N03AX12
ATC
[U] gabapentin; oral
2.5
25.6
197
906
M54.5
ICD-10 Finland
Low back pain
2.0
25.0
416
2595
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
39.9
25.0
31
8
M25.5
ICD-10 Finland
Pain in joint
2.0
24.0
382
2338
N03AX16
ATC
[U] pregabalin
2.2
23.5
260
1390
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
21.5
133
548
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.6
20.9
128
525
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.3
20.2
81
263
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
20.2
113
443
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
19.0
304
1837
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
+∞
18.8
18
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
18.8
368
2373
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.7
18.8
35
63
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
18.6
319
1970
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
18.4
465
3233
M79.6
ICD-10 Finland
Pain in limb
1.8
17.9
438
3010
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
37.4
17.7
22
6
M05BX04
ATC
denosumab; parenteral
3.7
17.3
55
153
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
6.5
17.2
28
44
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
5.1
17.0
36
73
M01AC06
ATC
meloxicam; systemic, rectal
1.8
16.9
375
2494
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
16.7
445
3116
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
+∞
16.7
16
*
N02BE01
ATC
paracetamol; systemic, rectal
2.3
16.3
908
7905
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
16.1
117
519
M01AH05
ATC
etoricoxib; oral
1.7
15.9
641
5011
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.2
15.7
63
204
NF1AA
NOMESCO Finland
Hip X-ray examination
2.8
15.7
83
315
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.7
386
2633
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
15.5
236
1391
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
15.4
201
1125
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.2
275
1711
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
57.5
14.8
17
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
14.6
364
2480
B01AB05
ATC
enoxaparin; parenteral
1.8
14.6
295
1894
SPAT1153
SPAT
Removal of sutures
1.8
14.6
309
2011
318
Kela drug reimbursment
Teriparatide
54.1
13.8
16
*
M01AB05
ATC
diclofenac; systemic, rectal
1.7
13.8
668
5387
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.0
13.6
29
59
M80, M85,
ICD-10 Finland
+∞
13.6
13
*
UJF32
NOMESCO Finland
Coloscopy
1.8
13.5
239
1469
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
13.3
74
288
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
6.4
13.3
22
35
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
13.2
156
839
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.4
13.1
47
142
M01AH02
ATC
rofecoxib; oral
2.2
13.1
122
600
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
13.0
126
629
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
12.9
89
385
H05AA02
ATC
teriparatide; parenteral
50.7
12.9
15
*
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
10.7
12.8
24
23
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
5.6
12.6
24
44
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
5.7
12.5
23
41
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
12.4
95
431
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.6
12.4
40
113
A02BC02
ATC
pantoprazole; systemic
1.6
12.3
644
5223
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
12.2
242
1533
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.7
12.2
67
260
M03BX02
ATC
tizanidine; oral
1.6
12.0
635
5144
J01DB01
ATC
cefalexin; oral
1.8
12.0
841
7332
N02AA05
ATC
oxycodone; systemic
2.0
11.9
145
787
L03
ICPC
Low back symptom/complaint
1.7
11.9
285
1901
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
11.9
110
539
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
11.7
193
1158
ZXA05
NOMESCO Finland
Left side
1.8
11.7
224
1405
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
30.4
11.7
15
5
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
11.6
106
517
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
+∞
11.5
11
*
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.7
11.5
26
56
M84.0
ICD-10 Finland
Malunion of fracture
121.3
11.4
12
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.5
11.4
76
324
L04AX03
ATC
methotrexate; systemic
2.2
11.3
105
516
R51.80
ICD-10 Finland
Headache
1.8
11.1
172
1011
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
11.1
267
1780
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.9
11.0
32
84
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
4.2
10.9
29
71
L88
ICPC
Rheumatoid/seropositive arthritis
3.0
10.7
47
161
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
10.6
143
802
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
10.6
199
1237
J01AA02
ATC
doxycycline; systemic
1.6
10.6
746
6371
M05BB03
ATC
alendronic acid and colecalciferol; oral
5.1
10.6
22
44
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
5.1
10.6
22
44
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
3.3
10.5
40
126
L17
ICPC
Foot/toe symptom/complaint
1.6
10.4
279
1906
NHR99
NOMESCO Finland
Other operation for tumour of ankle or foot
+∞
10.4
10
*
J01FF01
ATC
clindamycin; systemic
1.7
10.4
259
1739
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.4
10.3
37
112
A03FA02
ATC
cisapride; oral, rectal
2.4
10.3
69
295
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
10.1
112
587
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
10.1
728
6209
S18
ICPC
Laceration/cut
1.5
10.1
421
3186
WX212
NOMESCO Finland
Femoral plexus blockade
4.5
10.1
24
54
A02BC03
ATC
lansoprazole; oral
1.6
10.0
264
1794
M01AE02
ATC
naproxen; oral, rectal
1.5
10.0
577
4679
M81.8
ICD-10 Finland
Other osteoporosis
14.7
10.0
16
11
ZXA00
NOMESCO Finland
Right side
1.7
10.0
235
1551
SPAT1229
SPAT
Assessment of need for aid
2.4
9.9
66
281
M80
ICD-10 Finland
Osteoporosis with pathological fracture
26.3
9.8
13
5
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
20.2
9.8
14
7
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
3.9
9.7
28
73
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.3
9.7
76
348
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.6
9.7
54
211
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
9.7
236
1572
NDK00
NOMESCO Finland
Excision or incsion of a bone of wrist
55.5
9.7
11
*
L28
ICPC
Limited function/disability (L)
1.8
9.6
145
843
M01AH01
ATC
celecoxib; oral
1.8
9.6
160
960
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
9.5
935
8568
A07AA02
ATC
nystatin; oral
2.6
9.5
57
231
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
9.5
76
351
M85.2
ICD-10 Finland
Hyperostosis of skull
+∞
9.4
9
*
M85.1
ICD-10 Finland
Skeletal fluorosis
+∞
9.4
9
*
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
+∞
9.4
9
*
NF3AA
NOMESCO Finland
Femur X-ray examination
4.0
9.4
26
66
M02AA07
ATC
piroxicam; topical
1.6
9.3
315
2265
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.1
9.2
95
486
WX320
NOMESCO Finland
Spinalanesthesy
1.6
9.2
222
1474
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
9.1
59
248
H02AB06
ATC
prednisolone; systemic
1.5
9.1
436
3379
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
9.1
153
920
M79.7
ICD-10 Finland
Fibromyalgia
2.8
9.1
44
160
A02BC05
ATC
esomeprazole; systemic
1.5
9.1
376
2826
X58
ICD-10 Finland
Exposure to other specified factors
1.8
8.9
146
871
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.8
350
2602
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
8.8
122
691
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
2.9
8.6
40
142
L08
ICPC
Shoulder symptom/complaint
1.6
8.6
200
1313
S72.0
ICD-10 Finland
Fracture of neck of femur
3.4
8.5
30
90
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
27.8
8.5
11
*
N06AX21
ATC
duloxetine; oral
1.9
8.5
118
669
L20
ICPC
Joint symptom/complaint NOS
2.8
8.4
42
155
Q78.1
ICD-10 Finland
Polyostotic fibrous dysplasia
90.8
8.4
9
*
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
90.8
8.4
9
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
+∞
8.3
8
*
SPAT1216
SPAT
Assessment of functional ability
1.8
8.3
123
712
SPAT1301
SPAT
No procedures
1.5
8.2
285
2054
L11
ICPC
Wrist symptom/complaint
2.0
8.1
95
508
ZXD20
NOMESCO Finland
Day surgery
1.8
8.1
126
739
M84.1
ICD-10 Finland
Nonunion of fracture [pseudarthrosis]
33.6
8.1
10
*
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
33.6
8.1
10
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
8.1
689
5931
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
8.0
122
710
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.0
8.0
34
115
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
3.3
8.0
29
89
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
8.0
68
323
N06AA09
ATC
amitriptyline; systemic
2.0
7.8
86
451
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
7.8
118
687
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
15.2
7.7
12
8
R4110, ,
SPAT
2.0
7.7
83
431
P01BA02
ATC
hydroxychloroquine; oral
2.0
7.7
80
410
SPAT1263
SPAT
Sampling
1.5
7.7
398
3103
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.8
7.6
38
141
WZC30
NOMESCO Finland
Teaching
1.7
7.6
136
832
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.5
177
1162
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.5
520
4273
R52.9
ICD-10 Finland
Pain, unspecified
1.9
7.5
94
514
UJD02
NOMESCO Finland
Gastroscopy
2.5
7.5
47
195
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
4.3
7.5
19
45
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.8
7.4
120
711
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.8
7.4
36
131
M93.2
ICD-10 Finland
Osteochondritis dissecans
80.7
7.4
8
*
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
80.7
7.4
8
*
M01AX17
ATC
nimesulide; oral
1.6
7.4
198
1343
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.3
190
1277
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
7.3
95
526
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
7.3
139
863
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
7.3
74
376
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
+∞
7.3
7
*
NFK99
NOMESCO Finland
Other operation on bone of femur
+∞
7.3
7
*
W19
ICD-10 Finland
Unspecified fall
1.9
7.3
90
491
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
7.2
233
1645
M89.0
ICD-10 Finland
Algoneurodystrophy
15.9
7.2
11
7
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
7.2
541
4501
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.2
380
2965
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.1
403
3182
R60.0
ICD-10 Finland
Localized oedema
1.9
7.1
98
553
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.1
129
791
M81.5
ICD-10 Finland
Idiopathic osteoporosis
12.1
7.1
12
10
H02AB04
ATC
methylprednisolone; systemic
1.7
7.1
125
761
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.0
7.1
31
107
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.7
7.1
22
61
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.2
7.0
18
43
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.0
210
1458
R74
ICPC
Upper respiratory infection acute
1.5
7.0
339
2598
ACC51
NOMESCO Finland
Release of median nerve
2.0
7.0
77
403
NH1AD
NOMESCO Finland
Ankle and foot CT
3.4
7.0
24
71
L99
ICPC
Musculoskeletal disease other
3.3
7.0
25
76
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
6.9
271
1991
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.9
124
758
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
6.9
66
329
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
6.9
53
242
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
6.8
93
524
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.8
221
1562
NHA30
NOMESCO Finland
Exploration of joint of ankle or foot, arthroscopic
9.4
6.8
13
14
9104
FHL
Autogenous bone graft
40.3
6.8
8
*
M94.2
ICD-10 Finland
Chondromalacia
40.3
6.8
8
*
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.5
6.8
41
168
EDA10
NOMESCO Finland
Biopsy of mandible
22.7
6.7
9
*
Z01.2
ICD-10 Finland
Dental examination
1.4
6.7
443
3590
M01AC01
ATC
piroxicam; systemic, rectal
1.8
6.6
107
634
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
5.9
6.6
17
29
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.6
279
2081
D07AC01
ATC
betamethasone; topical
1.4
6.5
322
2472
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.1
6.5
64
322
M23.8
ICD-10 Finland
Other internal derangements of knee
2.5
6.5
39
159
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.5
370
2915
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.1
6.5
61
302
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.1
6.5
61
302
R4120
NOMESCO Finland
Occupational therapy
2.1
6.5
63
316
M85
ICD-10 Finland
Other disorders of bone density and structure
70.3
6.4
7
*
J02AC01
ATC
fluconazole; systemic
1.4
6.4
381
3021
A02BC04
ATC
rabeprazole; oral
1.8
6.4
90
512
J01EA01
ATC
trimethoprim; systemic
1.5
6.4
230
1659
R25.2
ICD-10 Finland
Cramp and spasm
2.9
6.4
28
97
L04AA13
ATC
[U] leflunomide
2.9
6.4
28
97
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.8
6.3
31
114
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
18.1
6.3
9
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.3
131
834
9105
FHL
Homogeneous or heterogeneous bone graft, e.g., joint graft
+∞
6.3
6
*
M93.8
ICD-10 Finland
Other specified osteochondropathies
+∞
6.3
6
*
NBK10
NOMESCO Finland
Partial or total excision of bone of shoulder or upper arm, humerus
+∞
6.3
6
*
M89.9
ICD-10 Finland
Disorder of bone, unspecified
+∞
6.3
6
*
J01CA04
ATC
amoxicillin; systemic
1.5
6.2
820
7449
M02AA10
ATC
ketoprofen; topical
1.6
6.2
136
875
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
4.0
6.2
17
43
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
4.0
6.2
17
43
XG410
NOMESCO Finland
Flow-volume spirometry
2.5
6.2
38
157
M01AH03
ATC
valdecoxib; oral
2.1
6.2
54
260
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.9
6.1
28
99
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
6.1
173
1184
N02BF01
ATC
gabapentin; oral
1.9
6.1
73
395
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
6.1
183
1271
ZZH31
NOMESCO Finland
Bone allograft, small pieces
6.1
6.0
15
25
M54.3
ICD-10 Finland
Sciatica
2.0
6.0
60
304
R01AD09
ATC
mometasone; nasal
1.4
6.0
442
3625
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
35
13
27.81
25.90
2.4
2.9
82.58
82.32
ug/l
0.00
35
13
524
3649
1.89
21.82
7.7
6.0
1.22
1.21
mmol/l
1.56
456
3108
186
897
2.31
21.42
5.3
5.4
1.06
1.05
mmol/l
0.19
172
836
764
6058
2.02
21.03
5.0
3.8
11.69
10.69
mm/h
1.15
715
5620
465
3278
1.76
17.23
6.4
5.4
1.22
1.21
mmol/l
1.06
432
2994
754
6188
1.82
15.71
8.0
7.0
75.26
76.63
u/l
0.49
723
5812
586
4522
1.69
14.77
4.7
4.3
6.43
6.59
mmol/l
1.25
546
4174
437
3165
1.66
13.72
5.1
4.5
36.45
36.33
g/l
0.19
398
2962
445
3269
1.64
13.01
12.6
10.9
1.15
1.19
inr
0.57
138
1007
948
8567
2.37
12.83
16.6
12.7
139.83
139.68
mmol/l
1.25
938
8330
235
1462
1.79
12.70
1.4
1.3
28.48
27.52
iu/ml
0.04
75
473
942
8514
2.27
12.34
16.0
11.5
18.57
21.95
mg/l
2.54
765
6587
947
8596
2.29
11.95
16.8
12.8
3.95
3.95
mmol/l
0.06
936
8342
103
496
2.20
11.64
1.9
2.6
68.30
67.10
g/l
1.08
92
456
224
1409
1.75
11.54
1.4
1.3
12.60
9.71
u/ml
0.23
86
560
775
6649
1.67
11.16
4.7
3.9
14.69
14.62
pmol/l
0.36
714
6113
440
3318
1.57
10.97
3.3
2.2
78.26
75.10
nmol/l
1.67
405
3003
350
2516
1.59
10.65
3.3
3.2
2.35
2.36
mmol/l
0.96
318
2252
510
4012
1.54
10.30
5.6
5.9
9.82
10.85
umol/l
1.93
486
3791
338
2436
1.58
10.06
3.0
2.4
52.53
60.50
u/l
2.63
314
2261
586
4770
1.53
9.98
8.0
8.5
4.19
3.96
e9/l
1.43
520
4170
182
1124
1.75
9.88
2.7
2.4
122.94
117.64
ug/g
0.09
150
900
376
2785
1.55
9.88
3.5
3.1
42.91
38.34
ng/l
0.14
234
1749
131
739
1.89
9.56
2.5
2.0
362.60
375.93
nmol/l
0.31
117
680
485
3837
1.50
9.15
2.7
2.5
—
—
—
0
0
98
509
2.02
9.09
3.7
3.8
75.14
79.59
ng/l
0.19
83
460
285
2034
1.56
8.62
1.4
1.3
1.07
1.73
u/ml
0.84
89
547
872
7875
1.71
8.61
5.7
4.6
1.71
2.00
mu/l
1.20
812
7295
166
1039
1.71
8.52
2.5
2.2
2.41
2.38
g/l
0.32
156
963
493
4004
1.44
7.65
6.8
5.7
28.52
29.01
%
0.47
463
3774
488
3956
1.44
7.65
6.5
5.4
56.68
56.45
%
0.16
457
3728
263
1891
1.53
7.56
2.4
2.1
2.85
2.94
mg/l
0.30
221
1624
186
1236
1.62
7.54
2.0
1.7
1074.14
1185.87
nmol/l
1.11
140
947
401
3143
1.45
7.48
3.7
3.3
—
—
—
0
0
152
963
1.68
7.42
2.7
2.3
22.75
23.75
%
0.41
126
833
56
253
2.28
7.42
6.4
7.2
1.60
1.53
%
0.20
56
234
501
4103
1.43
7.31
3.8
3.2
0.00
0.01
estimate
0.80
93
737
295
2189
1.49
7.24
2.2
2.0
136.05
210.50
u/l
1.58
276
2060
494
4041
1.43
7.23
3.8
3.2
0.00
0.00
estimate
0.50
98
800
266
1955
1.49
6.78
2.5
2.5
2805.63
5305.74
umol/l
0.66
228
1732
170
1139
1.59
6.62
2.6
2.2
13.50
13.82
umol/l
0.24
163
1059
488
4053
1.39
6.20
5.2
4.4
0.00
0.00
estimate
0.50
94
776
25
83
3.06
6.10
1.6
1.5
35.35
64.73
%
4.07
17
55
96
565
1.77
6.10
2.2
2.4
12.14
25.99
au/ml
—
8
51
102
616
1.73
5.93
2.4
2.6
10.21
10.67
g/l
0.63
95
558
99
606
1.70
5.49
7.0
8.9
127.12
121.28
g/l
2.08
99
590
38
167
2.32
5.43
2.2
4.0
32.80
83.43
mg/l
0.74
28
135
113
720
1.64
5.38
6.3
8.0
0.99
1.05
mmol/l
0.07
89
574
53
270
2.02
5.26
2.5
1.8
—
—
—
0
0
959
9107
1.79
5.25
11.6
9.3
25.90
26.48
u/l
0.49
938
8808
1002
9663
2.46
5.20
22.8
17.1
40.34
40.45
%
0.24
937
9110
242
1836
1.42
5.05
2.6
1.8
0.77
1.10
mg/l
2.63
179
1375
821
7550
1.43
5.04
5.6
5.1
38.35
39.03
mmol/mol
1.57
774
7051
33
141
2.38
5.03
7.5
10.9
104.67
105.08
mmol/l
0.17
33
126
37
167
2.26
4.99
2.2
4.0
21.27
33.10
mg/l
2.17
27
136
1002
9675
2.41
4.96
22.8
17.1
4.51
4.54
e12/l
0.98
984
9420
41
194
2.16
4.94
1.4
1.4
—
—
—
0
0
27
106
2.59
4.91
1.2
1.2
—
—
—
0
0
1002
9679
2.39
4.89
23.0
17.2
135.66
136.22
g/l
0.66
997
9549
51
264
1.98
4.86
1.5
1.5
0.00
0.04
iu/ml
—
9
50
1001
9669
2.34
4.81
22.8
17.1
261.51
254.64
e9/l
2.66
985
9437
112
733
1.59
4.80
4.8
4.5
225.61
256.09
u/l
1.47
99
692
36
165
2.22
4.70
2.2
4.0
1.37
2.23
ratio
—
5
14
366
3000
1.34
4.68
2.2
1.9
99.99
95.79
pmol/l
0.86
207
1545
53
282
1.93
4.68
1.6
1.4
9.40
9.54
u/l
0.03
46
227
871
8131
1.47
4.64
4.6
4.1
5.79
5.83
mmol/l
0.50
807
7465
46
234
2.01
4.61
1.5
1.6
—
215.00
—
0
8
110
726
1.58
4.55
6.6
8.0
5.08
5.10
kpa
0.06
103
697
162
1165
1.46
4.48
3.7
3.2
0.81
0.82
mmol/l
0.74
146
1104
66
384
1.77
4.41
1.6
1.9
—
—
—
0
0
45
231
1.99
4.41
1.4
1.2
11.42
9.69
u/ml
—
9
38
79
488
1.67
4.27
2.4
1.6
—
—
—
0
0
24
96
2.54
4.23
1.5
1.3
—
—
—
0
0
231
1787
1.38
4.23
4.1
3.4
1.02
1.02
kg/l
0.09
53
240
95
619
1.59
4.16
3.7
3.5
1.68
2.00
mmol/l
0.53
74
506
96
628
1.58
4.14
3.7
3.5
5.82
5.85
kpa
0.10
91
606
108
726
1.54
4.13
6.8
8.0
12.84
12.50
kpa
0.29
100
699
38
189
2.05
4.08
1.8
1.5
—
—
—
0
0
228
1771
1.37
4.06
1.5
1.4
2.22
2.34
g/l
0.58
148
1093
51
282
1.85
4.04
2.5
1.9
—
—
—
0
0
43
227
1.93
3.92
1.4
1.2
4.20
2.76
u/ml
—
5
25
333
2754
1.31
3.85
3.2
3.2
28.67
31.40
u/l
1.37
326
2629
153
1122
1.43
3.81
2.2
1.8
—
—
—
0
0
87
570
1.57
3.74
4.6
3.1
1.23
1.23
mmol/l
0.08
82
485
240
1904
1.34
3.70
2.4
2.1
—
—
—
0
0
47
261
1.84
3.70
1.3
1.3
—
—
—
0
0
645
5829
1.29
3.67
3.4
2.9
43.47
42.83
u/l
0.06
609
5490
130
937
1.44
3.56
4.3
4.1
32.90
31.83
%
0.62
98
652
202
1574
1.35
3.50
1.7
1.6
101657887.36
34822535.26
pmol/l
0.57
181
1321
10
22
4.58
3.43
1.6
1.0
—
—
—
0
0
84
558
1.55
3.42
2.5
2.2
11.02
12.91
nmol/l
1.41
75
515
211
1662
1.34
3.40
1.6
1.5
23.17
21.17
nmol/l
1.02
188
1414
439
3811
1.27
3.37
3.3
2.7
103.17
108.46
ug/l
0.25
404
3547
265
2159
1.31
3.36
4.2
3.4
0.00
0.01
estimate
1.28
90
755
673
6146
1.28
3.36
3.4
3.3
—
—
—
0
0
41
226
1.85
3.33
1.5
1.4
258.43
299.26
ug/g
0.60
24
136
127
925
1.43
3.29
6.3
5.9
—
—
—
0
0
848
7998
1.34
3.22
13.5
10.5
86.22
85.95
ml/min/173m2
0.13
706
6481
45
259
1.77
3.19
2.1
1.8
—
—
—
0
0
883
8392
1.37
3.09
4.4
4.0
4.68
4.74
mmol/l
1.13
835
7865
80
539
1.53
3.08
3.8
3.4
4.49
4.62
pmol/l
0.47
69
479
52
318
1.67
2.99
1.4
1.2
2.92
1.23
u/ml
—
5
26
34
183
1.89
2.99
1.8
1.7
—
—
—
0
0
170
1322
1.34
2.97
3.0
2.7
2.43
2.44
mmol/l
0.40
151
1169
893
8520
1.37
2.89
4.8
4.4
2.78
2.84
mmol/l
1.09
840
7938
878
8356
1.35
2.89
4.3
4.0
1.48
1.48
mmol/l
0.06
829
7794
114
835
1.41
2.88
5.7
6.4
105.10
104.38
mmol/l
0.99
114
835
40
230
1.77
2.87
1.6
2.1
3.43
3.55
g/l
0.32
35
215
197
1574
1.31
2.85
2.6
2.3
6.40
7.04
e6/l
0.24
180
1409
43
255
1.72
2.78
1.1
1.1
—
—
—
0
0
27
138
1.98
2.77
1.3
1.3
1.43
4.09
u/ml
—
7
44
226
1849
1.28
2.74
3.7
2.8
1023.81
1001.35
ng/l
0.05
185
1541
39
230
1.72
2.59
1.6
2.1
—
—
—
0
0
39
230
1.72
2.59
1.6
2.1
7.14
7.37
g/l
0.31
34
215
18
81
2.24
2.55
8.3
6.3
11.63
11.16
mg/l
0.21
18
75
6
11
5.48
2.54
1.2
1.2
—
—
—
0
0
31
172
1.83
2.52
1.8
1.4
—
—
—
0
0
39
232
1.71
2.52
2.4
2.0
0.42
2.78
ug/l
1.24
31
211
47
294
1.63
2.52
1.7
1.8
—
—
—
0
0
13
52
2.52
2.36
1.4
1.2
—
—
—
0
0
26
140
1.88
2.33
1.1
1.1
—
—
—
0
0
266
2269
1.23
2.22
3.3
2.9
145.16
59.85
e6/l
0.33
218
1719
35
210
1.69
2.22
1.6
2.2
9.58
10.45
g/l
0.79
30
194
69
487
1.45
2.18
1.1
1.0
—
—
—
0
0
36
219
1.67
2.18
3.6
2.2
11.50
11.33
mg/l
0.05
36
205
64
446
1.46
2.16
4.1
3.4
5.02
5.17
kpa
1.03
59
430
14
61
2.31
2.15
1.6
2.3
5.00
2.09
u/field
—
5
32
45
291
1.57
2.14
3.0
2.9
45.58
48.45
%
0.28
45
286
61
422
1.47
2.14
4.3
3.3
1.12
1.69
mmol/l
0.76
45
312
31
183
1.72
2.10
1.6
1.7
988.91
14847.56
e6/l
3.70
22
142
42
269
1.59
2.09
1.4
2.3
1.51
1.43
g/l
0.23
33
237
841
8043
1.25
2.06
3.9
3.6
1.26
1.27
mmol/l
0.16
792
7463
35
216
1.64
2.02
1.5
2.2
2.74
2.92
g/l
0.59
30
201
25
141
1.79
1.98
1.4
1.3
2.56
5.48
u/ml
—
9
58
6
16
3.77
1.93
1.2
1.3
—
—
—
0
0
9
33
2.74
1.93
1.6
1.6
—
—
—
0
0
9
33
2.74
1.93
1.1
1.2
—
—
—
0
0
90
683
1.35
1.90
2.2
2.3
0.22
0.22
g/l
0.05
82
644
8
28
2.87
1.86
1.1
1.1
—
—
—
0
0
18
93
1.95
1.86
1.1
1.1
—
—
—
0
0
75
555
1.38
1.85
2.5
2.3
6.61
7.45
ug/l
0.21
55
499
24
137
1.77
1.84
1.1
1.1
—
—
—
0
0
5
12
4.18
1.82
1.4
1.3
—
—
—
0
0
5
12
4.18
1.82
1.2
3.2
1.19
1.22
mmol/l
—
5
12
61
437
1.42
1.82
2.6
2.3
1728.49
4338.21
u/l
1.28
25
190
12
53
2.28
1.81
1.0
1.1
1.04
1.05
u/l
—
7
29
16
80
2.02
1.80
1.1
1.3
—
—
—
0
0
32
200
1.62
1.79
1.5
2.4
1.20
0.88
g/l
0.19
27
183
80
603
1.35
1.77
2.5
2.4
63.84
70.38
ml/min/173m2
0.68
32
248
275
2404
1.20
1.76
3.9
3.1
7.49
7.88
mmol/l
0.74
247
2057
31
193
1.63
1.76
1.2
1.3
—
—
—
0
0
77
578
1.36
1.75
9.4
6.9
8.25
8.77
mmol/l
0.34
71
551
6
18
3.35
1.75
1.0
1.8
7.23
17.05
umol/l
—
6
18
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
186
1.63
1.73
3.5
2.9
0.34
0.39
u/ml
0.35
16
102
7
24
2.93
1.72
1.4
1.2
—
—
—
0
0
165
1376
1.24
1.70
4.4
3.4
191.43
371.86
ng/l
0.89
118
967
64
469
1.39
1.69
1.6
1.4
30.71
26.57
iu/l
0.41
56
397
29
180
1.63
1.68
2.3
1.6
—
—
—
0
0
6
19
3.17
1.66
1.3
2.6
—
—
—
0
0
6
19
3.17
1.66
1.3
2.6
—
—
—
0
0
239
2076
1.20
1.64
3.3
2.8
0.24
0.46
e6/l
1.92
193
1542
29
182
1.61
1.61
1.2
1.3
153.79
229.50
u/ml
1.66
14
104
22
128
1.73
1.61
2.5
1.6
—
—
—
0
0
22
128
1.73
1.61
2.5
1.6
—
—
—
0
0
87
680
1.31
1.54
1.1
1.2
74.92
143.48
iu/ml
2.86
34
271
21
123
1.72
1.51
1.6
1.6
—
—
—
0
0
19
109
1.76
1.47
2.1
1.3
—
—
—
0
0
19
109
1.76
1.47
2.1
1.3
—
—
—
0
0
787
7552
1.18
1.46
17.9
13.9
14.82
14.57
%
0.56
781
7418
14
73
1.93
1.44
1.4
1.2
—
—
—
0
0
19
110
1.74
1.43
2.1
1.3
—
—
—
0
0
22
133
1.67
1.43
1.2
1.3
—
—
—
0
0
22
133
1.67
1.43
1.2
1.3
—
—
—
0
0
19
111
1.73
1.39
2.1
1.3
—
—
—
0
0
14
74
1.90
1.39
1.4
1.2
—
—
—
0
0
29
190
1.54
1.38
1.5
1.2
—
—
—
0
0
106
864
1.25
1.37
2.1
2.9
5.13
7.75
umol/l
2.23
93
740
19
112
1.71
1.36
2.1
1.3
—
—
—
0
0
19
112
1.71
1.36
2.1
1.3
—
—
—
0
0
17
97
1.77
1.35
2.1
2.4
—
—
—
0
0
12
61
1.98
1.33
1.2
1.2
—
—
—
0
0
22
137
1.62
1.30
2.2
2.2
17.11
16.31
%
0.39
15
68
10
48
2.09
1.28
1.5
1.5
2.00
1.76
u/field
—
5
37
221
1949
1.17
1.27
4.7
3.6
95.17
93.56
%
0.41
212
1896
73
916
0.78
1.24
1.6
1.6
—
—
—
0
0
10
49
2.05
1.22
1.4
2.3
—
—
—
0
0
5
19
2.64
1.21
1.4
1.1
109.20
99.47
%
—
5
19
14
78
1.81
1.21
2.6
1.7
—
—
—
0
0
28
189
1.49
1.19
3.4
2.7
—
—
—
0
0
27
181
1.50
1.19
1.6
2.2
38.80
38.39
g/l
0.11
22
166
8
38
2.11
1.18
3.1
1.7
—
—
—
0
0
8
38
2.11
1.18
3.3
1.7
—
—
—
0
0
37
265
1.41
1.18
5.7
2.3
98.97
92.61
%
1.27
32
257
95
780
1.24
1.17
2.0
1.8
—
—
—
0
0
94
771
1.24
1.17
2.0
1.7
—
—
—
0
0
11
57
1.94
1.17
1.0
1.1
—
—
—
0
0
15
87
1.73
1.15
2.5
1.6
—
—
—
0
0
19
295
0.64
1.14
1.2
1.5
—
—
—
0
0
0
36
0.00
1.14
0.0
4.0
—
—
—
0
0
23
151
1.54
1.12
4.6
5.9
677.60
337.15
iu/ml
—
5
20
8
40
2.01
1.12
2.0
2.9
844.38
760.58
u/ml
—
8
40
8
40
2.01
1.12
1.9
1.2
—
—
—
0
0
26
176
1.49
1.11
2.4
1.6
—
—
—
0
0
7
31
2.27
1.10
2.4
2.2
—
—
—
0
0
47
613
0.76
1.09
1.3
1.6
—
—
—
0
0
20
129
1.56
1.06
2.2
1.6
—
—
—
0
0
97
812
1.21
1.02
2.2
1.9
—
—
—
0
0
127
1091
1.19
1.02
5.4
2.0
29.75
29.37
s
0.29
122
1057
30
215
1.41
0.98
1.4
1.4
66.15
227.46
pmol/l
1.33
30
209
146
1275
1.17
0.97
2.0
2.0
—
—
—
0
0
23
157
1.48
0.96
3.5
3.8
59.61
56.54
%
0.39
23
157
142
1238
1.17
0.96
2.8
2.5
1.22
0.97
e6/l
0.31
86
672
6
27
2.23
0.93
3.8
1.9
—
—
—
0
0
6
27
2.23
0.93
3.8
1.9
—
—
—
0
0
183
1631
1.15
0.93
1.5
1.5
—
—
—
0
0
12
70
1.72
0.93
2.5
1.6
—
—
—
0
0
12
70
1.72
0.93
2.5
1.6
—
—
—
0
0
12
70
1.72
0.93
2.5
1.6
—
—
—
0
0
24
337
0.71
0.91
1.5
1.4
—
—
—
0
0
6
28
2.15
0.91
4.2
1.8
—
—
—
0
0
22
151
1.47
0.91
3.3
3.5
4.28
4.21
e9/l
0.04
22
151
24
336
0.71
0.90
1.5
1.4
—
—
—
0
0
24
335
0.71
0.89
1.5
1.4
—
—
—
0
0
24
335
0.71
0.89
1.5
1.4
—
—
—
0
0
134
1173
1.16
0.88
3.0
2.7
3.33
3.19
e6/l
0.06
80
607
240
2193
1.12
0.84
1.8
1.7
1.40
1.37
mmol/l
0.22
215
1862
86
728
1.20
0.84
2.7
2.3
34.29
104.68
u/l
0.54
78
613
16
105
1.53
0.82
1.3
1.5
—
—
—
0
0
27
362
0.74
0.80
1.6
1.5
—
—
—
0
0
128
1127
1.16
0.79
1.9
1.8
1.42
1.43
%
0.01
112
1014
6
33
1.82
0.79
2.3
2.4
—
—
—
0
0
41
322
1.28
0.79
1.7
1.7
—
—
—
0
0
14
90
1.56
0.78
2.0
1.5
—
—
—
0
0
14
90
1.56
0.78
2.0
1.5
—
—
—
0
0
15
221
0.67
0.76
1.1
1.5
—
—
—
0
0
9
53
1.70
0.75
1.0
1.0
—
—
—
0
0
5
24
2.09
0.74
4.2
1.9
—
—
—
0
0
13
196
0.66
0.74
1.0
1.1
0.20
3.18
u/ml
—
5
103
7
38
1.85
0.73
2.4
2.3
24.01
226.85
ug/l
—
7
33
7
38
1.85
0.73
2.0
1.2
—
—
—
0
0
7
38
1.85
0.73
2.0
1.2
—
—
—
0
0
204
1864
1.12
0.72
5.2
4.5
2.37
2.48
ug/l
0.07
186
1689
7
40
1.76
0.71
2.0
1.2
—
—
—
0
0
7
40
1.76
0.71
1.1
1.1
115.21
174.32
iu/ml
—
7
40
18
126
1.44
0.70
1.4
1.1
—
—
—
0
0
48
391
1.24
0.70
1.6
1.6
—
—
—
0
0
22
161
1.37
0.68
1.7
1.7
—
—
—
0
0
39
313
1.26
0.66
1.2
1.4
—
—
—
0
0
10
62
1.62
0.65
1.2
1.2
—
—
—
0
0
204
1878
1.11
0.64
1.7
1.6
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
239
2220
1.10
0.63
4.3
3.8
7.54
8.23
mg/mmol
0.12
159
1384
155
1413
1.11
0.59
2.2
2.1
—
—
—
0
0
20
265
0.75
0.59
1.7
1.7
—
—
—
0
0
228
2121
1.10
0.58
3.6
3.3
554.41
263.52
mg/l
0.36
149
1348
10
64
1.57
0.58
1.0
1.0
274.80
294.25
mg/l
—
10
56
0
23
0.00
0.58
0.0
1.8
—
1.83
—
0
11
8
54
1.49
0.57
1.4
1.5
—
—
—
0
0
11
73
1.51
0.56
2.5
2.2
—
—
—
0
0
75
655
1.16
0.55
2.1
1.8
—
—
—
0
0
6
37
1.63
0.55
1.3
1.1
2331.50
1705.19
miu/ml
—
6
37
9
60
1.50
0.54
1.3
2.0
—
—
—
0
0
12
170
0.70
0.53
2.5
1.5
—
—
—
0
0
11
74
1.49
0.53
2.5
3.2
16.36
75.37
u/ml
1.50
11
74
9
63
1.43
0.52
1.7
1.3
84.33
75.24
umol/l
—
9
63
77
679
1.14
0.51
2.9
4.4
7.96
15.75
ug/l
0.56
60
550
6
41
1.47
0.50
2.5
2.8
42733.33
41504.88
ug/l
—
6
41
12
167
0.72
0.49
1.0
1.1
1.55
1.54
u/ml
—
5
84
12
84
1.43
0.49
6.2
4.3
54.80
57.09
u/ml
—
6
24
12
84
1.43
0.49
1.3
1.5
—
—
—
0
0
9
131
0.68
0.43
1.4
1.3
—
—
—
0
0
29
239
1.22
0.43
7.0
2.6
3.56
3.64
g/l
0.13
29
229
29
239
1.22
0.43
2.9
1.9
6.53
5.38
iu/l
0.20
14
84
10
139
0.72
0.42
1.1
1.2
—
—
—
0
0
5
33
1.52
0.41
1.8
1.7
2.00
1.88
nmol/l
—
5
26
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.2
1.5
—
—
—
0
0
5
35
1.43
0.39
1.2
1.5
—
—
—
0
0
11
81
1.36
0.36
2.5
2.4
106.36
105.77
mmol/l
0.21
11
81
11
81
1.36
0.36
2.5
2.4
4.04
3.97
mmol/l
0.19
11
81
6
43
1.40
0.35
1.2
1.0
31.67
33.21
ng/l
—
6
25
6
43
1.40
0.35
1.2
1.0
383.00
240.81
ng/l
—
6
27
6
43
1.40
0.35
1.2
1.0
939.17
687.93
ng/l
—
6
27
30
351
0.85
0.34
1.6
1.4
—
—
—
0
0
12
91
1.32
0.34
1.6
1.5
—
—
—
0
0
102
1101
0.92
0.33
3.2
2.9
0.68
0.74
ug/l
0.26
64
673
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
47
417
1.13
0.32
1.4
1.4
—
—
—
0
0
6
47
1.28
0.32
1.0
1.3
—
15.60
—
0
10
18
147
1.23
0.31
1.2
1.0
3.67
2.18
u/ml
—
8
68
7
55
1.27
0.30
3.7
3.5
—
—
—
0
0
32
366
0.87
0.29
1.6
1.3
257.80
242.77
miu/ml
0.09
16
194
8
62
1.29
0.28
1.1
1.5
—
—
—
0
0
20
168
1.19
0.27
1.5
1.4
133.10
105.26
u/ml
—
10
35
16
132
1.22
0.25
1.6
1.3
6.72
7.49
mmol/l
0.59
16
113
15
123
1.22
0.25
1.9
1.5
—
—
—
0
0
9
77
1.17
0.24
1.2
1.1
—
—
—
0
0
9
77
1.17
0.24
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
13
157
0.83
0.22
2.2
3.4
24.56
26.33
mg/l
—
7
101
10
79
1.27
0.22
1.1
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.8
—
1131650.00
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.03
—
0
6
0
10
0.00
0.21
0.0
1.1
—
37.00
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
24
211
1.14
0.20
1.3
1.2
—
—
—
0
0
21
183
1.15
0.20
2.5
2.2
79.97
91.18
ug/min
0.09
15
112
6
48
1.25
0.20
1.2
1.2
11466.67
59685.68
e6/l
—
6
25
13
108
1.21
0.20
2.1
1.4
—
—
—
0
0
15
127
1.18
0.19
1.1
1.1
—
—
—
0
0
23
259
0.89
0.18
1.3
1.2
—
—
—
0
0
7
61
1.15
0.17
1.7
1.2
—
—
—
0
0
5
68
0.73
0.17
1.6
1.1
—
—
—
0
0
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
10
83
1.21
0.15
1.0
1.0
—
—
—
0
0
9
78
1.16
0.15
1.2
1.1
—
—
—
0
0
9
78
1.16
0.15
1.2
1.1
—
—
—
0
0
9
78
1.16
0.15
1.2
1.1
—
—
—
0
0
155
1501
1.04
0.15
4.6
4.0
20.50
21.11
%
0.23
71
657
79
753
1.05
0.14
3.5
2.9
—
—
—
0
0
8
100
0.80
0.13
1.4
1.4
—
—
—
0
0
17
152
1.12
0.12
1.1
1.1
—
—
—
0
0
11
95
1.16
0.11
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.4
1.6
—
—
—
0
0
6
55
1.09
0.09
2.0
1.4
118.73
171.98
pmol/l
—
6
55
14
153
0.91
0.07
1.5
3.3
31.71
34.79
umol/l
0.29
14
142
39
378
1.03
0.04
2.1
1.7
2.38
4.75
mg/l
0.86
31
274
10
109
0.92
0.04
1.0
1.1
—
—
—
0
0
53
518
1.02
0.03
1.3
1.3
—
—
—
0
0
25
260
0.96
0.03
1.3
1.2
—
—
—
0
0
10
98
1.02
0.00
1.2
1.2
—
—
—
0
0
11
108
1.02
0.00
1.1
1.8
—
1744.00
—
0
5
36
358
1.01
0.00
1.6
1.4
—
—
—
0
0
41
408
1.01
0.00
1.1
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
4.93
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
1.5
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
2.2
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
12.00
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.2
2.8
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_BONEDENSOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BONEDENSOTH | 1.323 [1.12, 1.56] | < 0.001 |
| Birth year | 0.995 [0.99, 1.01] | 0.332 |
During the follow-up period (1.1.1998 — 31.12.2019), 397 out of 3559 females with M13_BONEDENSOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BONEDENSOTH | 1.259 [1.08, 1.47] | 0.004 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 307 out of 2959 males with M13_BONEDENSOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_BONEDENSOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.162% | 0.24% |
| 5 | 0.766% | 1.641% |
| 10 | 1.882% | 3.791% |
| 15 | 3.928% | 7.102% |
| 20 | 6.893% | 11.974% |
Relationships between endpoints
↥Index endpoint: M13_BONEDENSOTH – Other disorders of bone density and structure
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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