≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Melanocytic naevi of scalp and neck

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_MELANOCYTIC_SCALPNECK

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D22.4&
  • Hospital discharge: ICD-9 — 2164A
  • Cause of death: ICD-10 — D22.4&
  • Cause of death: ICD-9 — 2164A

2 out of 7 registries used, show all original rules.

931

4. Check minimum number of events

None

931

5. Include endpoints

None

931

6. Filter based on genotype QC (FinnGen only)

907

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) verticis cranii

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6814 3784 3011
Only index persons 6315 3553 2762
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.08
Only index persons 0.12 0.13 0.11
Median age at first event (years)
Whole population 35.03 34.26 35.95
Only index persons 36.18 35.14 37.52

-FinnGen-

Key figures

All Female Male
Number of individuals 907 552 355
Unadjusted period prevalence (%) 0.18 0.20 0.16
Median age at first event (years) 47.64 41.87 56.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
931
Matched controls
9310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
19.9
307.7
406
348
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
6230.7
307.7
895
37
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
7.3
108.4
179
294
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.2
81.8
157
297
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
11.6
73.2
78
73
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.2
72.9
173
395
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
9.3
47.1
58
66
TQW99
NOMESCO Finland
Other minor procedure on skin
5.5
45.7
94
187
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
8.4
44.8
60
76
2164A
ICD-9 Finland
Benign neoplasm of skin, Scalp and skin of neck[PÄÄN JA KAULAN IHON BEN KASV,NAEVUS PIGMENTOSUS]
+∞
37.8
36
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
4.2
36.6
104
269
L57.0
ICD-10 Finland
Actinic keratosis
3.4
31.4
126
412
L82
ICD-10 Finland
Seborrhoeic keratosis
2.7
30.5
203
880
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.8
28.1
90
253
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.8
27.7
89
251
XQ845
NOMESCO Finland
Dermatoscopy
7.5
26.9
39
54
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
6.2
26.6
46
77
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.4
26.2
223
1079
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.2
25.4
53
106
ZZR00
NOMESCO Finland
Flap of skin
6.2
20.9
36
60
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
6.2
19.1
33
55
9733
FHL
Excision of skin change in operating room or anesthesia
6.3
19.0
32
52
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
5.2
18.2
38
76
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.9
17.2
38
80
XQ848
NOMESCO Finland
Dermatological photography
4.3
17.2
45
109
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.5
17.0
42
97
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
15.7
15
*
D23.4
ICD-10 Finland
Benign neoplasm: Skin of scalp and neck
5.9
15.0
27
47
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.7
14.8
34
74
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.9
14.7
43
113
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
152.3
14.5
15
*
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
5.4
14.3
28
53
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.2
14.2
29
57
S82
ICPC
Naevus/mole
2.1
14.0
147
761
S18
ICPC
Laceration/cut
1.7
13.2
409
2958
127
Kela drug reimbursment
Transplant complication
5.6
13.1
25
46
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
19.4
12.9
19
10
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.9
12.4
58
206
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
11.6
64
249
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
11.3
11.6
21
19
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
4.8
11.2
25
53
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.8
11.0
34
93
L72.1
ICD-10 Finland
Trichilemmal cyst
2.5
11.0
70
292
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
16.2
10.4
16
10
SPAT1153
SPAT
Removal of sutures
1.6
10.0
266
1819
Z94.0
ICD-10 Finland
Kidney transplant status
7.5
9.7
22
30
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
17.7
9.4
14
8
C43.49
ICD-10 Finland
Malignant melanoma of the scalp and neck other or unspecified histology
+∞
9.4
9
*
L91.0
ICD-10 Finland
Hypertrophic scar
4.4
9.4
23
53
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
4.6
9.1
21
46
ZXC50
NOMESCO Finland
Cryotherapy
3.4
8.7
31
94
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
7.7
8.7
19
25
PJA12
NOMESCO Finland
Sentinel node biopsy
2.2
8.6
69
320
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
27.8
8.5
11
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.2
8.5
22
53
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.9
8.5
24
62
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
9.6
8.3
16
17
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.2
8.3
32
102
D06BB10
ATC
imiquimod; topical
2.4
8.1
55
237
D22
ICD-10 Finland
Melanocytic naevi
2.4
8.0
56
245
ZXA00
NOMESCO Finland
Right side
1.6
7.8
207
1406
L04AX01
ATC
azathioprine; systemic
2.6
7.6
42
164
C43
ICD-10 Finland
Malignant melanoma of skin
25.2
7.6
10
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
7.7
7.4
16
21
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
6.0
7.4
19
32
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.4
7.3
15
18
L04AA01
ATC
[U] ciclosporin
5.7
7.1
19
34
Z2221
NOMESCO Finland
Medical doctor
1.5
6.9
241
1736
TQW40, ,
SPAT
2.1
6.6
64
320
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
10.1
6.5
12
12
J01DB01
ATC
cefalexin; oral
1.5
6.5
741
6672
C08CA02
ATC
felodipine; oral
2.0
6.4
67
345
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
14.4
6.4
10
7
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.4
353
2777
A02BC02
ATC
pantoprazole; systemic
1.4
6.2
551
4706
J01FF01
ATC
clindamycin; systemic
1.5
6.2
221
1596
137
Kela drug reimbursment
Uraemia requiring dialysis
6.3
6.2
15
24
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
12.6
6.1
10
8
B05DA
ATC
Isotonic solutions
6.8
6.0
14
21
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.3
6.0
22
68

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
514
2984
2.61
44.85
2.7
2.0
—
—
—
0
0
204
928
2.53
27.55
1.6
1.2
—
—
—
0
0
68
296
2.40
9.77
1.4
1.2
—
—
—
0
0
105
580
1.91
8.20
1.6
1.4
—
—
—
0
0
378
2933
1.49
7.72
5.9
4.7
36.41
36.09
g/l
0.51
364
2742
114
686
1.75
6.75
2.8
2.6
1.71
1.77
%
0.30
104
614
87
490
1.86
6.41
2.5
2.7
67.81
71.28
e9/l
0.46
62
365
672
5953
1.46
6.19
4.0
3.9
14.65
14.61
pmol/l
0.12
627
5451
469
3924
1.39
5.80
7.0
5.5
1.91
1.95
e9/l
0.21
414
3525
470
3935
1.39
5.79
7.4
5.7
0.19
0.19
e9/l
0.16
412
3499
50
242
2.13
5.67
1.2
1.2
—
—
—
0
0
827
7704
1.66
5.58
15.7
12.6
21.70
22.13
mg/l
0.14
641
6046
454
3798
1.38
5.52
7.1
5.5
0.04
0.04
e9/l
0.36
395
3335
443
3710
1.37
5.26
7.6
6.0
10.24
11.04
umol/l
1.72
426
3514
859
8107
1.77
5.21
11.7
9.4
25.19
26.46
u/l
1.51
842
7845
771
7097
1.50
5.17
4.9
4.6
1.82
2.01
mu/l
0.57
732
6561
450
3792
1.36
5.08
7.1
5.5
0.56
0.57
e9/l
0.16
393
3327
427
3575
1.36
5.00
8.1
5.9
—
—
—
0
0
434
3675
1.34
4.58
6.8
5.4
57.14
56.90
%
0.16
407
3468
105
689
1.59
4.49
2.8
2.5
27.03
34.78
u/l
1.99
88
581
177
1299
1.45
4.46
3.6
3.6
388.96
312.91
ng/l
0.17
132
923
505
4388
1.33
4.40
10.7
8.4
4.00
4.05
e9/l
0.18
447
3860
898
8653
2.07
4.21
23.7
18.5
40.41
40.31
%
0.20
846
8171
898
8656
2.06
4.16
23.4
18.4
255.11
252.98
e9/l
0.45
889
8454
160
1167
1.45
4.16
2.9
2.6
0.72
0.93
e6/l
0.71
107
646
401
3391
1.32
4.14
8.9
6.6
1.22
1.21
mmol/l
0.27
355
2906
853
8105
1.63
4.13
14.1
11.8
—
—
—
0
0
435
3724
1.32
4.10
7.1
5.6
28.19
28.44
%
0.20
408
3516
898
8661
2.04
4.07
23.4
18.4
4.53
4.52
e12/l
0.21
886
8441
232
1813
1.37
4.05
5.9
3.6
94.21
92.44
%
0.48
224
1759
898
8664
2.03
4.02
23.4
18.4
6.65
6.72
e9/l
0.43
886
8439
421
3602
1.31
3.94
7.4
5.9
8.38
8.39
%
0.02
392
3388
362
3034
1.32
3.93
8.2
5.9
1.21
1.21
mmol/l
0.18
329
2770
584
5224
1.32
3.93
3.3
3.0
42.02
43.52
u/l
0.21
562
4933
27
120
2.29
3.83
1.2
1.2
—
—
—
0
0
127
903
1.47
3.76
3.3
2.4
22.54
23.27
%
0.27
112
776
417
3580
1.30
3.74
7.1
5.6
2.70
2.78
%
0.41
388
3364
125
887
1.47
3.74
2.2
1.7
—
—
—
0
0
306
2522
1.32
3.70
3.9
3.1
27.72
31.24
u/l
2.14
296
2401
9
16
5.67
3.66
4.4
4.6
—
—
—
0
0
786
7381
1.42
3.64
4.3
4.0
4.66
4.67
mmol/l
0.15
753
6913
757
7068
1.38
3.59
3.9
3.6
1.24
1.26
mmol/l
0.34
715
6560
15
51
2.97
3.58
1.2
1.4
5.89
6.40
ug/l
0.18
15
41
83
545
1.57
3.57
9.7
8.8
—
—
—
0
0
811
7680
1.43
3.37
17.4
14.0
139.66
139.61
mmol/l
0.24
802
7471
216
1717
1.34
3.32
3.8
3.4
—
—
—
0
0
794
7496
1.40
3.31
4.7
4.4
2.75
2.79
mmol/l
0.53
766
6978
10
23
4.38
3.31
3.3
2.9
—
—
—
0
0
263
2153
1.31
3.28
3.4
3.1
7.72
7.89
mmol/l
0.23
237
1834
357
3048
1.28
3.21
2.3
2.3
74.85
75.01
nmol/l
0.04
332
2765
616
5620
1.28
3.21
9.6
7.0
76.82
77.01
u/l
0.04
593
5276
362
3098
1.28
3.19
14.6
12.5
1.24
1.18
inr
0.41
83
951
768
7224
1.36
3.17
4.4
4.1
5.84
5.82
mmol/l
0.09
731
6641
248
2027
1.30
3.11
2.2
2.1
165.26
262.59
u/l
1.11
232
1909
99
699
1.47
3.06
1.5
1.5
—
—
—
0
0
811
7707
1.41
3.05
17.7
14.1
3.94
3.95
mmol/l
0.68
800
7483
88
611
1.49
2.96
4.4
3.7
1.92
1.93
mmol/l
0.01
75
498
778
7353
1.35
2.95
4.2
4.0
1.47
1.47
mmol/l
0.17
745
6857
119
876
1.41
2.95
1.6
1.4
—
—
—
0
0
144
1096
1.37
2.93
1.7
1.6
—
—
—
0
0
118
869
1.41
2.91
9.5
5.7
1.07
1.04
mmol/l
0.57
112
806
356
3068
1.26
2.90
3.2
3.1
5.84
5.78
ph
0.16
25
256
7
13
5.42
2.87
2.1
1.5
—
—
—
0
0
396
3459
1.25
2.86
7.3
5.7
0.71
0.66
%
0.96
368
3244
141
1074
1.37
2.85
3.2
2.4
13.27
13.61
umol/l
0.25
134
1001
159
1239
1.34
2.78
3.5
2.8
2.44
2.44
mmol/l
0.00
143
1087
414
3644
1.25
2.76
2.9
2.6
—
—
—
0
0
242
2001
1.28
2.75
6.2
3.7
7.40
7.40
ph
0.23
33
366
17
72
2.39
2.73
1.1
1.4
—
—
—
0
0
474
4240
1.24
2.71
5.6
4.7
6.40
6.58
mmol/l
1.32
425
3911
8
19
4.24
2.68
1.1
1.2
—
—
—
0
0
142
1096
1.35
2.64
4.5
3.4
0.83
0.82
mmol/l
0.45
133
1037
263
2210
1.26
2.61
2.7
2.9
—
—
—
0
0
224
1846
1.28
2.60
2.4
2.0
2.62
2.88
mg/l
0.90
189
1574
144
1118
1.34
2.58
2.9
2.7
2.10
2.54
e6/l
0.36
87
605
65
439
1.52
2.52
1.3
1.3
—
—
—
0
0
55
358
1.57
2.52
1.4
1.3
255.75
246.61
miu/ml
0.07
33
173
232
1931
1.27
2.48
3.5
2.9
0.22
0.47
e6/l
2.51
181
1445
8
21
3.83
2.46
2.0
1.4
—
—
—
0
0
79
561
1.45
2.41
4.5
3.4
—
—
—
0
0
5
8
6.28
2.37
1.6
1.6
58.80
91.25
ng/l
—
5
8
224
1870
1.26
2.32
3.7
3.3
425.95
253.05
mg/l
0.20
142
1231
21
105
2.02
2.32
2.9
3.1
—
—
—
0
0
18
85
2.14
2.30
8.1
6.1
13.29
11.06
mg/l
0.60
18
78
722
6821
1.26
2.28
18.5
14.9
14.51
14.57
%
0.11
715
6711
299
2585
1.23
2.26
4.0
3.5
28.66
91.77
e6/l
3.03
210
1764
226
1898
1.25
2.22
3.5
2.9
—
—
—
0
0
222
1861
1.25
2.22
9.5
6.3
—
—
—
0
0
10
35
2.88
2.21
1.2
1.1
791.60
1564.49
miu/ml
—
10
35
278
2391
1.23
2.20
2.9
2.2
—
—
—
0
0
29
166
1.77
2.17
1.7
1.5
—
—
—
0
0
547
5033
1.21
2.17
4.5
4.2
18.40
2461.67
e6/l
—
5
70
7
19
3.70
2.15
1.0
1.0
—
—
—
0
0
316
2760
1.22
2.14
2.0
1.9
96.81
96.02
pmol/l
0.10
158
1475
98
739
1.36
2.14
7.1
8.5
4.97
5.10
kpa
0.75
90
708
52
348
1.52
2.14
8.1
11.6
—
—
—
0
0
252
2151
1.24
2.13
3.4
3.0
54.04
100.70
e6/l
0.52
198
1643
98
740
1.36
2.12
7.1
8.4
12.48
12.50
kpa
0.01
90
711
112
866
1.33
2.08
4.1
2.6
6.40
7.98
umol/l
0.83
96
743
0
55
0.00
2.07
0.0
1.1
—
—
—
0
0
28
162
1.75
2.04
1.8
1.5
0.32
0.35
nmol/l
0.10
23
138
216
1822
1.24
2.03
2.8
2.2
—
—
—
0
0
97
738
1.35
2.01
7.2
8.5
0.15
1.12
mmol/l
1.84
74
583
567
5263
1.20
1.95
4.5
4.1
—
—
—
0
0
70
511
1.40
1.88
1.3
1.3
271.51
213.45
u/ml
0.21
65
469
16
79
2.04
1.86
1.4
1.6
—
—
—
0
0
260
2257
1.21
1.84
3.2
2.5
56.19
59.17
u/l
0.52
244
2090
46
662
0.68
1.81
4.6
3.5
—
—
—
0
0
22
123
1.81
1.81
1.2
1.4
—
—
—
0
0
62
449
1.41
1.76
1.4
1.4
25.00
24.24
iu/l
0.06
54
386
70
518
1.38
1.75
1.6
1.4
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
195
1654
1.23
1.74
1.8
1.7
—
—
—
0
0
7
24
2.93
1.72
4.1
2.7
—
33.00
—
0
5
700
6658
1.21
1.71
5.4
5.2
38.60
39.04
mmol/mol
0.65
667
6231
37
243
1.54
1.70
2.3
1.7
46.84
39.63
nmol/l
0.69
37
232
12
55
2.20
1.68
1.2
2.3
43.79
38.92
%
0.36
12
55
197
1682
1.22
1.65
3.7
3.6
1.01
1.02
kg/l
0.96
24
221
228
1976
1.20
1.63
4.9
4.8
2.02
2.49
ug/l
0.91
206
1763
269
2368
1.19
1.63
4.5
3.2
2.37
2.35
mmol/l
0.91
239
2114
126
1026
1.26
1.62
2.5
2.0
—
—
—
0
0
14
70
2.02
1.59
2.1
3.3
61.61
54.38
%
0.78
14
63
28
175
1.62
1.59
1.2
1.3
258.77
247.32
u/ml
0.07
13
101
42
289
1.47
1.58
1.5
1.4
10.22
9.14
u/l
0.19
35
244
33
491
0.66
1.56
1.7
1.6
—
—
—
0
0
16
85
1.90
1.55
1.3
1.2
—
—
—
0
0
226
1968
1.20
1.54
4.1
3.9
15.18
8.46
mg/mmol
0.85
141
1276
65
488
1.36
1.52
2.8
2.3
10975.65
3950.79
u/l
0.56
29
212
98
785
1.28
1.46
1.4
1.3
—
—
—
0
0
207
1797
1.20
1.45
3.6
2.6
351.65
6605.83
umol/l
6.90
184
1588
11
52
2.13
1.44
1.5
2.5
—
—
—
0
0
21
125
1.70
1.44
1.4
1.2
1.79
6.80
u/ml
1.56
14
49
6
22
2.74
1.43
1.3
1.4
—
—
—
0
0
45
322
1.42
1.40
1.3
1.3
—
—
—
0
0
64
486
1.34
1.40
3.0
3.0
66.49
66.91
g/l
0.17
57
447
14
74
1.91
1.39
2.7
1.3
—
—
—
0
0
64
487
1.34
1.39
1.2
1.2
—
—
—
0
0
171
1465
1.20
1.39
2.8
2.5
3.86
6.88
e6/l
3.19
156
1311
136
1147
1.22
1.30
2.9
2.9
0.69
0.76
ug/l
0.48
90
733
38
268
1.44
1.30
3.7
3.5
0.49
0.26
g/l
1.00
22
119
208
1830
1.18
1.25
4.4
4.1
—
—
—
0
0
29
195
1.50
1.25
1.3
1.3
—
—
—
0
0
195
1707
1.18
1.25
1.9
1.7
1.33
1.04
mg/l
0.50
151
1280
17
102
1.68
1.16
1.3
1.3
—
—
—
0
0
392
3630
1.14
1.16
3.3
2.8
90.23
103.78
ug/l
1.29
378
3383
0
36
0.00
1.14
0.0
1.0
—
16.71
—
0
27
227
2031
1.16
1.11
2.0
2.0
—
—
—
0
0
7
31
2.27
1.10
2.6
1.5
—
—
—
0
0
18
112
1.62
1.09
2.6
2.6
—
—
—
0
0
8
41
1.96
1.09
4.8
7.6
—
—
—
0
0
406
3782
1.13
1.08
3.6
3.4
0.00
0.00
estimate
0.50
58
777
7
33
2.13
1.05
1.0
1.2
—
—
—
0
0
11
60
1.84
1.03
2.5
1.5
203.96
179.37
pmol/l
0.40
11
60
7
34
2.07
1.03
2.1
2.6
37414.29
36970.74
ug/l
—
7
34
123
1055
1.19
1.01
1.4
1.3
460.65
474.07
titre
0.03
31
216
10
53
1.90
1.01
1.8
1.4
—
—
—
0
0
46
352
1.32
1.01
1.6
1.7
—
—
—
0
0
578
5515
1.13
1.01
4.3
3.9
10.58
10.78
mm/h
0.14
546
5110
51
399
1.29
0.97
2.5
2.5
—
—
—
0
0
179
1597
1.15
0.91
1.6
1.5
19.61
20.48
nmol/l
0.36
163
1368
194
2153
0.88
0.91
2.9
3.0
—
—
—
0
0
527
5019
1.12
0.91
3.8
3.5
—
—
—
0
0
33
245
1.36
0.90
2.1
2.7
—
—
—
0
0
197
1774
1.14
0.88
3.3
3.1
2579.36
1210.65
ng/l
1.01
177
1493
119
1035
1.17
0.86
2.4
2.4
122.53
116.69
ug/g
0.10
96
811
406
3823
1.11
0.85
3.6
3.4
0.00
0.01
estimate
0.80
52
708
362
3391
1.11
0.83
9.7
8.4
0.00
0.00
e9/l
0.78
286
2781
67
554
1.23
0.83
2.9
2.3
11.12
12.15
nmol/l
0.44
62
502
52
419
1.26
0.81
1.6
1.7
—
—
—
0
0
6
33
1.82
0.79
1.5
4.4
—
—
—
0
0
66
549
1.22
0.78
2.7
2.5
9.55
6.96
ug/l
0.29
60
495
28
208
1.36
0.78
1.4
1.4
257.89
304.93
ug/g
0.38
13
121
400
3777
1.10
0.78
4.9
4.6
0.00
0.00
estimate
0.50
55
736
0
27
0.00
0.77
0.0
1.3
—
72.82
—
0
18
6
34
1.77
0.76
4.0
3.5
813.83
578.68
u/ml
—
6
34
9
54
1.67
0.74
1.1
1.5
—
—
—
0
0
52
632
0.81
0.74
1.2
1.2
72.47
152.44
iu/ml
1.86
18
257
8
133
0.60
0.74
1.0
1.0
—
—
—
0
0
60
498
1.22
0.74
2.8
3.4
4.69
4.61
pmol/l
0.14
53
442
72
609
1.20
0.73
4.0
4.3
2.93
31.59
ug/l
1.40
57
500
43
344
1.26
0.73
2.1
2.4
—
—
—
0
0
5
26
1.93
0.70
1.6
2.0
—
—
—
0
0
10
61
1.65
0.68
1.1
1.4
81.00
78.08
umol/l
—
10
61
11
69
1.60
0.68
1.6
1.2
—
—
—
0
0
11
69
1.60
0.68
2.2
1.1
—
—
—
0
0
9
59
1.53
0.68
2.2
1.2
—
—
—
0
0
78
904
0.85
0.68
1.3
1.3
—
—
—
0
0
77
661
1.18
0.68
6.9
4.1
—
—
—
0
0
64
543
1.19
0.65
1.3
1.4
—
—
—
0
0
22
163
1.36
0.64
2.0
1.9
154.45
208.78
pmol/l
0.94
22
153
5
29
1.73
0.64
5.0
3.2
48.50
33.86
umol/l
—
5
21
12
79
1.53
0.62
2.3
4.2
—
—
—
0
0
8
49
1.64
0.62
1.1
1.0
—
—
—
0
0
9
137
0.65
0.61
1.0
1.1
—
—
—
0
0
87
763
1.15
0.60
1.5
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
52
1.54
0.59
1.1
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
2.0
—
16.16
—
0
22
54
456
1.20
0.59
1.5
1.7
—
—
—
0
0
7
113
0.62
0.58
1.3
1.6
—
—
—
0
0
109
976
1.13
0.57
1.2
1.2
—
—
—
0
0
54
458
1.19
0.56
1.5
1.7
—
—
—
0
0
54
460
1.18
0.54
1.5
1.7
—
—
—
0
0
9
61
1.48
0.53
1.0
1.1
312.33
220.04
mg/l
—
9
53
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
9
64
1.41
0.51
1.1
1.1
60.11
40.65
mg/l
—
9
49
9
65
1.39
0.50
3.0
3.4
—
—
—
0
0
79
700
1.14
0.50
2.5
1.9
351.42
381.63
nmol/l
0.72
73
650
53
456
1.17
0.49
1.5
1.6
—
—
—
0
0
7
111
0.63
0.48
1.0
1.0
—
0.60
—
0
37
42
493
0.84
0.46
2.9
2.8
—
—
—
0
0
7
49
1.43
0.46
1.3
1.2
—
—
—
0
0
5
82
0.61
0.46
5.6
8.1
6.60
6.76
mmol/l
—
5
64
38
320
1.20
0.45
1.8
1.8
—
—
—
0
0
24
192
1.26
0.45
2.6
3.2
—
—
—
0
0
30
247
1.22
0.44
5.6
4.9
—
—
—
0
0
9
130
0.69
0.43
1.0
1.4
—
—
—
0
0
32
267
1.21
0.42
1.3
1.3
—
—
—
0
0
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
37
314
1.19
0.41
2.0
2.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
266
2791
0.93
0.41
2.4
2.6
—
—
—
0
0
41
352
1.17
0.41
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
16
125
1.28
0.37
2.7
2.5
—
—
—
0
0
94
1024
0.91
0.37
1.4
1.5
—
—
—
0
0
9
70
1.29
0.36
1.6
2.5
—
—
—
0
0
16
126
1.27
0.35
1.3
1.4
—
—
—
0
0
11
82
1.35
0.34
1.1
2.1
—
—
—
0
0
15
188
0.79
0.33
3.1
2.4
—
—
—
0
0
6
86
0.70
0.33
1.2
1.0
—
—
—
0
0
30
349
0.85
0.33
3.3
3.3
—
—
—
0
0
12
154
0.78
0.32
1.0
1.1
1.30
2.15
u/ml
—
6
81
7
52
1.35
0.31
1.0
1.0
—
0.43
—
0
15
65
591
1.11
0.31
3.4
4.2
1.09
1.04
%
0.08
27
204
11
84
1.31
0.30
1.8
2.8
—
—
—
0
0
20
166
1.21
0.30
1.5
2.1
4.64
4.75
umol/l
0.03
14
120
7
56
1.25
0.29
1.3
1.2
—
—
—
0
0
7
57
1.23
0.29
1.0
1.2
—
—
—
0
0
7
57
1.23
0.29
2.9
1.6
0.76
1.01
g/l
—
7
57
15
121
1.24
0.28
1.2
1.2
—
—
—
0
0
46
413
1.12
0.28
3.8
6.0
—
—
—
0
0
58
528
1.11
0.27
3.5
4.3
0.00
0.77
%
0.67
19
141
11
139
0.79
0.27
7.4
3.5
4.57
4.44
e9/l
0.05
11
139
8
66
1.21
0.26
1.8
2.0
32.75
33.09
pg
—
8
66
18
150
1.20
0.26
2.1
1.2
—
—
—
0
0
48
528
0.90
0.25
5.3
3.6
1.22
1.23
mmol/l
0.17
42
457
11
87
1.27
0.24
2.2
2.7
—
—
—
0
0
201
1936
1.05
0.22
4.0
3.6
—
—
—
0
0
7
93
0.75
0.22
1.1
1.3
—
—
—
0
0
60
556
1.08
0.21
3.5
4.3
0.00
0.13
%
3.91
22
169
21
241
0.87
0.21
6.5
9.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
12
98
1.23
0.21
2.6
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.6
2.4
44.80
46.96
umol/l
—
5
36
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
147
1409
1.05
0.20
2.9
2.7
512.22
555.56
mosm/kgh2o
1.48
124
1212
12
144
0.83
0.20
7.2
3.8
58.58
58.09
%
0.07
12
144
6
53
1.13
0.18
1.5
1.5
—
—
—
0
0
91
959
0.94
0.18
1.9
1.8
—
—
—
0
0
57
532
1.08
0.18
2.6
2.6
3.72
6.83
e9/l
1.70
49
454
14
119
1.18
0.17
1.1
1.2
—
—
—
0
0
7
61
1.15
0.17
1.6
1.4
—
—
—
0
0
123
1278
0.96
0.16
1.3
1.2
15.74
11.03
u/ml
0.24
49
503
57
536
1.07
0.15
3.3
4.1
0.57
0.65
%
0.17
22
172
263
2572
1.03
0.15
3.6
3.4
91.42
34.48
ng/l
1.04
159
1615
173
1684
1.03
0.13
1.6
1.5
2.04
2.26
g/l
1.24
104
1045
34
316
1.08
0.12
4.6
3.7
—
—
—
0
0
14
123
1.14
0.12
1.4
1.6
—
—
—
0
0
16
179
0.89
0.12
1.1
1.1
0.58
3.23
u/ml
—
7
96
14
158
0.88
0.12
1.1
1.1
16.81
8.52
u/ml
—
6
89
120
1163
1.04
0.12
1.6
1.7
1244.24
1164.02
nmol/l
0.35
88
891
206
2016
1.03
0.11
4.3
3.7
0.02
0.01
estimate
0.22
54
716
68
651
1.05
0.11
1.1
1.2
—
—
—
0
0
21
192
1.10
0.11
1.0
1.2
—
—
—
0
0
14
125
1.12
0.10
2.5
2.3
17.59
16.17
%
—
8
64
5
45
1.11
0.10
1.2
1.2
—
—
—
0
0
5
47
1.06
0.09
3.0
1.6
0.00
1.26
u/field
—
5
36
5
48
1.04
0.09
1.4
1.5
1.59
1.53
g/l
—
5
48
5
48
1.04
0.09
2.8
3.6
—
—
—
0
0
29
309
0.94
0.09
1.6
1.5
—
—
—
0
0
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
6
56
1.07
0.08
2.8
1.2
1.00
1.42
nmol/l
—
6
51
186
1892
0.98
0.08
1.7
1.7
1.45
1.37
mmol/l
0.52
170
1597
246
2429
1.02
0.07
1.5
1.6
—
—
—
0
0
9
87
1.03
0.07
1.1
1.3
—
—
nmol/l
—
0
0
33
346
0.95
0.06
1.0
1.1
—
—
—
0
0
12
132
0.91
0.06
2.3
2.5
—
—
—
0
0
11
99
1.11
0.06
1.1
1.3
0.63
0.55
nmol/l
0.58
11
91
135
1329
1.02
0.05
1.3
1.3
39.42
30.65
iu/ml
0.27
40
423
29
303
0.96
0.05
1.5
1.4
—
—
—
0
0
15
161
0.93
0.05
1.1
1.1
—
—
—
0
0
14
150
0.93
0.04
1.1
1.1
—
10.50
—
0
13
15
160
0.94
0.04
1.1
1.1
—
—
—
0
0
29
301
0.96
0.04
1.5
1.4
—
—
—
0
0
44
428
1.03
0.03
4.6
3.7
7.40
7.41
ph
—
5
49
14
131
1.07
0.03
2.2
1.8
—
—
—
0
0
141
1426
0.99
0.03
1.4
1.7
53600457.66
21494203.34
pmol/l
0.25
125
1205
23
240
0.96
0.03
1.1
1.2
—
—
—
0
0
17
161
1.06
0.03
1.1
1.1
—
—
—
0
0
29
299
0.97
0.02
1.7
1.7
—
—
—
0
0
12
113
1.06
0.02
1.4
1.9
—
1346.67
—
0
6
17
163
1.04
0.01
2.1
2.3
42.10
112.24
ug/min
—
10
102
192
1910
1.01
0.01
1.3
1.3
2.73
1.55
u/ml
0.48
47
504
12
114
1.05
0.00
1.2
1.1
—
—
—
0
0
14
134
1.05
0.00
1.5
1.7
—
—
—
0
0
13
136
0.96
0.00
2.7
4.0
—
—
—
0
0
12
116
1.03
0.00
3.3
2.8
—
—
—
0
0
17
174
0.98
0.00
1.2
1.3
—
—
—
0
0
10
102
0.98
0.00
1.2
1.5
—
—
—
0
0
14
142
0.99
0.00
2.6
3.0
—
—
—
0
0
20
202
0.99
0.00
1.8
2.1
—
—
—
0
0
125
1251
1.00
0.00
1.8
1.7
—
—
—
0
0
23
233
0.99
0.00
3.6
4.5
1.82
1.32
mmol/l
0.57
23
228
15
155
0.97
0.00
1.1
1.7
39965.78
15831.77
e6/l
—
9
115
0
8
0.00
0.00
0.0
9.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.3
5.84
0.50
u/ml
—
6
31
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
1.31
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
15.77
—
0
7
7
78
0.90
-0.00
1.0
1.1
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.3
6.54
6.49
mmol/l
—
5
54
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
17
170
1.00
-0.00
4.2
4.2
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.1
—
—
—
0
0
6
68
0.88
-0.00
2.7
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
6.55
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
331.17
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
17.87
—
0
7
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_SCALPNECK and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_SCALPNECK 0.786 [0.65, 0.95] 0.011
Birth year 0.992 [0.98, 1.0] 0.06

During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 3036 females with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_SCALPNECK 1.089 [0.92, 1.3] 0.336
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 295 out of 2431 males with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_SCALPNECK.

N-year risk Females Males
1 0.068% 0.168%
5 0.421% 1.092%
10 1.019% 2.71%
15 1.971% 5.418%
20 3.539% 9.434%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MELANOCYTIC_SCALPNECK – Melanocytic naevi of scalp and neck

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data