Syndactyly

Q17_SYNDACTYLY

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q70 Cause of death: ICD-10 — Q70 2 out of 7 registries used, show all original rules.	79
4. Check minimum number of events None	79
5. Include endpoints None	79
6. Filter based on genotype QC (FinnGen only)	78

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q6[5-9]|Q7
Name in latin: Syndactylia

NAME	Q17_SYNDACTYLY
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q70
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q70
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Syndactyly based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1551	578	972
Only index persons	1116	439	677
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.03
Only index persons	0.02	0.02	0.03
Median age at first event (years)
Whole population	2.12	3.83	1.06
Only index persons	4.99	9.40	2.12

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	78	50	28
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	21.97	16.30	32.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q70.9

ICD-10 Finland

Syndactyly, unspecified

+∞

42.6

Q70.1

ICD-10 Finland

Webbed fingers

+∞

17.3

Q70.0

ICD-10 Finland

Fused fingers

+∞

15.1

NDT38

NOMESCO Finland

Correction of joined fingers

+∞

14.0

Q70.3

ICD-10 Finland

Webbed toes

+∞

11.7

AA1AD

NOMESCO Finland

CT of head and brain

5.0

9.4

7551A

ICD-9 Finland

Other congenital anomalies of limbs, Syndactyly[SYNDACTYLIA]

+∞

8.5

9493

FHL

Reconstruction or shaping of hand skin and soft tissues, e.g. syndactyl

+∞

7.4

ZXA00

NOMESCO Finland

Right side

4.1

6.6

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

3.6

6.6

109

108

Kela drug reimbursment

Myasthenia gravis

+∞

6.3

75512

ICD-8 Finland

Other congenital anomalies of limbs, Syndactylia cum reductione phalangis, manus

+∞

6.3

G70.0

ICD-10 Finland

Myasthenia gravis

+∞

6.3

N07AA02

ATC

pyridostigmine; systemic

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3022217) INR in Platelet poor plasma by Coagulation assay

197

2.52

3.86

15.2

7.5

1.09

1.10

inr

—

(3023368) Bacteria identified in Blood by Culture

110

2.70

3.66

3.8

3.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.82

3.14

2.4

1.4

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

4.82

2.88

7.3

2.4

0.50

0.57

—

(3012544) pH of Venous blood

2.88

2.79

6.9

4.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.46

2.66

5.2

2.5

281.92

303.98

ng/l

0.03

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.33

2.64

7.6

2.7

126.50

137.10

g/l

—

(3044290) Cell count panel - Cerebral spinal fluid

5.80

2.59

1.5

2.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

3.77

2.57

1.6

1.4

—

(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma

6.58

2.40

1.2

1.0

1.41

1.32

g/l

—

(3002582) Erythrocytes [#/volume] in Urine

176

2.02

2.21

4.0

2.9

14.50

62.16

e6/l

0.75

129

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

186

1.99

2.15

3.7

3.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.35

2.15

1.4

1.7

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

5.25

2.10

1.0

1.5

—

(3030467) Casts [#/volume] in Urine by Automated count

155

2.01

2.07

2.4

2.9

0.18

0.19

e6/l

0.02

112

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.06

1.92

1.3

1.8

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

4.03

1.74

5.4

3.5

68.70

61.30

—

(3018095) Leukocytes [#/volume] in Urine

207

1.82

1.72

4.7

3.4

14.82

21.61

e6/l

0.37

133

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.35

1.71

1.3

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.33

1.69

1.8

1.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

236

1.77

1.65

1.9

1.8

—

(40768804) Tissue Pathology biopsy report

239

0.50

1.56

1.6

1.8

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

187

1.77

1.53

10.3

4.8

36.36

37.56

g/l

0.52

182

(3025941) Bacteria identified in Stool by Culture

2.34

1.47

1.8

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

234

1.70

1.45

9.3

7.0

1.22

mmol/l

0.14

213

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

139

1.81

1.43

4.1

2.3

16.85

51.31

ng/l

0.53

(36304419) Bacteria [Presence] in Urine

156

1.77

1.42

2.5

2.7

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

2.02

1.40

1.6

800000331.50

455.91

pmol/l

0.78

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.06

1.38

1.8

2.3

2.58

2.46

g/l

0.37

(3022145) Colonoscopy Study observation

2.23

1.35

1.6

1.3

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.18

1.32

50.4

8.4

1.62

1.23

mmol/l

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.94

1.27

10.7

3.5

0.79

0.81

mmol/l

0.27

(40760892) CBC W Ordered Manual Differential panel - Blood

298

1.61

1.25

7.2

5.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.08

1.24

1.3

1.4

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.74

1.23

1.0

1.1

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.74

1.23

7.8

5.1

2.70

3.75

g/l

—

(3006504) Eosinophils/100 leukocytes in Blood

310

1.59

1.19

6.8

5.1

2.93

2.85

0.11

290

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.30

1.11

1.0

1.2

—

(40768443) Skin Pathology biopsy report

2.47

1.10

1.0

1.2

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.80

0.99

1.8

2.3

16.40

15.88

umol/l

0.07

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.94

0.97

10.2

6.7

105.80

105.53

mmol/l

—

(3018010) Neutrophils/100 leukocytes in Blood

321

1.50

0.96

6.6

4.9

53.28

56.26

0.87

302

(40758558) Short blood count panel - Blood

147

1.58

0.93

5.4

7.3

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

210

1.52

0.92

4.1

2.7

36.11

31.50

u/l

0.27

202

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

113

1.64

0.92

4.3

2.3

1.04

0.68

mg/l

0.45

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.74

0.81

58.6

7.2

23.88

24.26

mmol/l

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.74

0.81

11.9

1.9

10.12

10.05

g/l

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.80

0.0

2.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.83

0.78

3.0

1.4

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.25

0.77

79.8

9.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.61

0.76

2.3

2.9

1.93

4.19

e6/l

—

(3026008) Bacteria identified in Urine by Culture

154

1.50

0.75

2.8

2.6

—

(3000991) Gas panel - Venous blood

1.65

0.74

49.3

8.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.77

0.72

1.9

2.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

129

1.51

0.71

3.9

2.3

87.06

685.90

u/l

0.69

129

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

277

1.40

0.70

5.2

5.5

8.77

10.41

umol/l

0.74

257

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.58

0.70

2.1

2.9

1.78

0.80

e6/l

—

(3022096) Basophils/100 leukocytes in Blood

297

1.39

0.69

7.3

5.1

0.73

0.67

0.36

278

(3028026) IgM [Mass/volume] in Serum or Plasma

1.69

0.69

1.6

1.5

1.28

1.12

g/l

—

(21494755) Public health laboratory ask at order entry panel

103

0.55

0.67

1.3

1.2

—

(4200892) Spirometry reversibility

1.77

0.65

1.0

1.3

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.8

—

1.18

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.8

—

0.22

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.59

0.57

1.2

1.7

—

(3044640) Blood type and Crossmatch panel - Blood

190

1.38

0.57

2.8

2.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

299

1.31

0.50

3.6

2.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

202

0.74

0.44

2.7

2.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

653

1.45

0.43

18.6

9.7

27.54

21.39

mg/l

0.60

479

(3009508) Creatinine [Moles/volume] in Urine

158

0.72

0.42

2.7

2.6

7.12

8.63

mmol/l

0.62

139

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

180

1.31

0.42

1.8

1.7

104.90

95.68

pmol/l

0.37

(3044889) 12 lead EKG panel

354

1.26

0.42

3.0

2.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

600

1.35

0.42

4.5

4.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.47

0.41

3.0

2.6

837.30

5978.81

u/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.50

0.41

1.8

1.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

548

1.30

0.41

13.3

8.5

94.00

96.73

ml/min/173m2

0.41

423

(3013512) EKG study

107

1.37

0.40

3.4

2.7

—

(3000494) Fungus identified in Specimen by Culture

1.43

0.40

2.9

1.2

—

(3002256) Pathology report gross observation

1.39

0.40

1.1

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

297

1.25

0.39

4.2

3.0

0.00

estimate

—

(3042936) Bacteria identified in Isolate by Culture

1.45

0.39

2.6

1.7

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

462

0.81

0.37

4.9

3.1

45.52

39.45

u/l

0.20

442

(1761868) Lipid panel - Serum or Plasma

218

0.77

0.36

2.2

2.1

—

(3022313) Gas panel - Capillary blood

1.46

0.36

6.3

5.5

—

(3003396) Base excess in Arterial blood by calculation

1.39

0.35

67.0

8.3

-0.45

1.01

mmol/l

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.36

0.34

1.7

3.3

4.67

4.89

pmol/l

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.36

0.34

2.0

2.3

—

21.10

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

556

0.81

0.32

3.4

2.9

1.24

1.20

mmol/l

0.13

522

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

139

0.76

0.30

1.4

1.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

188

1.24

0.30

1.4

2.50

2.17

g/l

0.48

108

(3021601) Nitrite [Presence] in Urine by Test strip

295

1.20

0.29

5.8

4.4

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

300

1.17

0.23

4.3

3.0

0.00

estimate

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.27

0.23

1.2

4.1

1.92

12.02

ug/l

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.8

—

17.50

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

9.1

—

0.62

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

0.83

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.21

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.4

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.0

—

(40768793) Breast Pathology biopsy report

0.00

0.20

0.0

1.4

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.7

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.1

—

9.78

—

(40761536) Microorganisms panel - Urine sediment

1.22

0.20

3.0

3.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

120

0.81

0.18

1.4

1.5

—

(3027944) Amphetamines [Presence] in Urine

0.74

0.17

1.6

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.74

0.17

1.6

1.4

—

(3028300) Cannabinoids [Presence] in Urine

0.74

0.17

1.6

1.4

—

(3027008) Opiates [Presence] in Urine

0.74

0.17

1.6

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.72

0.17

1.4

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

217

1.15

0.17

1.5

1.7

—

(3026493) Urate [Moles/volume] in Serum or Plasma

119

0.82

0.17

1.9

3.0

272.10

326.62

umol/l

—

107

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.78

0.16

1.0

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

123

1.17

0.13

1.6

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

260

0.89

0.13

1.9

2.1

—

(3029937) Albumin [Presence] in Urine by Test strip

144

1.14

0.11

5.6

3.1

0.00

0.02

estimate

—

(3003694) ABO and Rh group [Type] in Blood

253

1.10

0.10

1.8

1.7

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.17

0.10

6.2

5.7

23.90

24.04

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

175

1.11

0.09

4.4

2.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.10

0.09

1.2

1.3

—

(3016879) Cocaine [Presence] in Urine

0.82

0.08

1.6

1.5

—

(40768797) Stomach Pathology biopsy report

1.03

0.08

1.1

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.07

0.08

1.4

1.5

—

(36660697) Celiac disease serology panel - Serum

1.08

0.07

1.1

1.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

193

0.91

0.07

1.5

1.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.13

0.07

1.2

2.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

103

0.86

0.07

1.9

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

139

1.10

0.06

3.6

2.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

181

0.92

0.05

2.8

2.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

438

0.96

0.02

4.4

3.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

223

1.04

0.01

5.2

2.9

—

(3021960) Folate [Moles/volume] in Serum or Plasma

112

0.98

0.00

1.6

1.3

26.32

19.86

nmol/l

0.74

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

142

0.98

0.00

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

145

0.96

0.00

3.2

2.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

124

0.96

0.00

2.0

1.8

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

-0.00

0.0

1.9

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.5

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.8

—

48.60

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.0

—

29.17

—

(40761511) CBC panel - Blood by Automated count

696

1.05

-0.00

14.6

8.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.92

-0.00

1.0

1.7

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

14.7

—

1041.67

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

89.10

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.40

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.0

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

-0.00

0.0

2.1

—

3.71

—

(3003181) Sodium [Moles/volume] in Urine

0.00

-0.00

0.0

1.6

—

60.00

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

10.23

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

-0.00

0.0

1.9

—

51.50

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

1.8

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

32.27

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.00

-0.00

2.2

1.5

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

24.2

—

1982.67

—

(3045424) Erythrocytes [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

1.6

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

5.5

—

0.89

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.6

—

1.20

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.6

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

-0.00

0.0

1.4

—

1.21

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

78.07

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

6.43

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_SYNDACTYLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_SYNDACTYLY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_SYNDACTYLY – Syndactyly

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Syndactyly

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints