Syndactyly

Q17_SYNDACTYLY

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q70 Cause of death: ICD-10 — Q70 2 out of 7 registries used, show all original rules.	78
4. Check minimum number of events None	78
5. Include endpoints None	78
6. Filter based on genotype QC (FinnGen only)	78

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q6[5-9]|Q7
Name in latin: Syndactylia

NAME	Q17_SYNDACTYLY
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q70
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q70
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Syndactyly based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1551	578	972
Only index persons	1116	439	677
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.03
Only index persons	0.02	0.02	0.03
Median age at first event (years)
Whole population	2.12	3.83	1.06
Only index persons	4.99	9.40	2.12

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	78	51	27
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	21.64	16.34	31.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
70: Matched controls
700

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q70.9

ICD-10 Finland

Syndactyly, unspecified

+∞

35.4

Q70.1

ICD-10 Finland

Webbed fingers

+∞

16.3

Q70.0

ICD-10 Finland

Fused fingers

+∞

12.9

NDT38

NOMESCO Finland

Correction of joined fingers

+∞

11.8

Q70.3

ICD-10 Finland

Webbed toes

+∞

11.8

7551A

ICD-9 Finland

Other congenital anomalies of limbs, Syndactyly[SYNDACTYLIA]

+∞

8.5

9493

FHL

Reconstruction or shaping of hand skin and soft tissues, e.g. syndactyl

+∞

7.4

G70.0

ICD-10 Finland

Myasthenia gravis

+∞

6.3

108

Kela drug reimbursment

Myasthenia gravis

+∞

6.3

N07AA02

ATC

pyridostigmine; systemic

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

111

2.52

3.13

3.9

3.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.78

3.06

2.4

1.4

—

(3032080) INR in Blood by Coagulation assay

175

2.28

2.97

6.5

5.4

1.1

inr

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

4.82

2.88

7.3

2.4

0.5

0.6

—

(3012544) pH of Venous blood

2.88

2.80

6.9

4.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.58

2.67

1.4

1.7

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.33

2.65

7.6

2.8

126.5

137.1

g/l

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

3.77

2.57

1.6

1.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.50

2.39

1.2

1.8

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.27

2.17

5.1

2.5

305.3

298.0

ng/l

0.01

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

5.26

2.10

1.0

1.5

—

(3044290) Cell count panel - Cerebral spinal fluid

4.37

1.85

1.4

2.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.40

1.78

1.3

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

172

1.87

1.75

3.1

2.9

14.9

63.6

e6/l

0.75

126

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

4.03

1.74

5.4

3.5

68.7

61.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.33

1.69

1.8

1.9

—

(42870588) Differential panel, method unspecified - Blood

209

1.80

1.67

6.8

5.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

183

1.83

1.66

3.1

3.0

—

(4306422)

3.74

1.64

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

229

1.76

1.60

1.9

1.8

—

(3030467) Casts [#/volume] in Urine by Automated count

152

1.84

1.56

2.5

2.9

0.2

e6/l

0.04

109

(40768804) Tissue Pathology biopsy report

238

0.50

1.55

1.6

1.8

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

232

1.73

1.51

9.2

7.0

1.2

mmol/l

0.08

212

(3025941) Bacteria identified in Stool by Culture

2.35

1.47

1.8

1.2

—

(3018095) Leukocytes [#/volume] in Urine

203

1.68

1.32

3.8

3.5

13.6

22.1

e6/l

0.48

130

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.12

1.29

1.3

1.4

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.74

1.23

1.0

1.1

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.74

1.23

7.8

5.1

2.7

3.7

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

139

1.70

1.16

3.7

2.3

17.9

51.5

ng/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.38

1.13

1.0

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.06

1.12

1.9

2.3

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.93

1.12

1.7

2.3

2.7

2.5

g/l

0.78

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.88

1.11

1.7

1.6

861538811.1

457.2

pmol/l

0.78

(40768443) Skin Pathology biopsy report

2.47

1.10

1.0

1.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.36

1.05

79.8

10.0

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

187

1.59

1.04

11.0

4.8

36.3

37.5

g/l

0.48

181

(36304419) Bacteria [Presence] in Urine

152

1.62

1.03

2.5

2.7

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.80

0.99

11.5

3.6

0.8

mmol/l

0.31

(3022145) Colonoscopy Study observation

2.01

0.92

1.6

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.74

0.81

58.6

7.2

23.9

24.3

mmol/l

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.80

0.0

2.4

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.83

0.78

2.5

3.1

—

0.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.68

0.77

1.7

2.3

16.3

15.7

umol/l

0.07

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

110

1.57

0.76

4.5

2.3

0.8

0.7

mg/l

0.18

(3000991) Gas panel - Venous blood

1.69

0.75

49.3

8.7

—

(40758558) Short blood count panel - Blood

149

1.46

0.66

5.7

7.3

—

(4010399)

1.71

0.62

1.0

1.3

—

(3026008) Bacteria identified in Urine by Culture

151

1.44

0.62

2.7

2.6

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.8

—

1.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.8

—

0.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

654

0.69

0.58

24.0

11.1

39.1

40.3

0.58

556

(3009508) Creatinine [Moles/volume] in Urine

156

0.66

0.57

2.5

2.6

7.4

8.6

mmol/l

0.43

137

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

209

1.37

0.57

3.5

2.7

32.5

31.6

u/l

0.05

201

(21494755) Public health laboratory ask at order entry panel

0.59

0.56

1.3

1.2

—

(3013512) EKG study

109

1.47

0.56

3.3

2.6

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

278

1.32

0.53

4.8

5.5

9.4

10.4

umol/l

0.35

258

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.48

0.52

2.4

2.9

1.9

4.2

e6/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.46

0.50

2.2

2.9

1.8

0.8

e6/l

—

(1761868) Lipid panel - Serum or Plasma

216

0.73

0.49

2.0

2.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.47

0.47

13.4

1.9

10.0

10.1

g/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

535

1.33

0.45

11.3

8.5

93.5

96.8

ml/min/173m2

0.52

410

(3044640) Blood type and Crossmatch panel - Blood

188

1.32

0.44

2.7

2.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

137

0.69

0.44

1.4

1.7

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.42

0.43

1.3

1.6

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

295

1.27

0.42

5.2

4.0

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.55

0.42

3.2

1.4

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.41

0.0

1.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

455

0.79

0.41

4.8

3.2

45.9

40.1

u/l

0.18

435

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.50

0.41

1.8

1.5

—

(3000494) Fungus identified in Specimen by Culture

1.43

0.40

2.9

1.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

645

1.42

0.40

16.9

9.8

29.7

21.7

mg/l

0.81

470

(3002256) Pathology report gross observation

1.39

0.40

1.1

1.2

—

(3022096) Basophils/100 leukocytes in Blood

297

1.26

0.39

7.6

5.2

0.7

0.23

278

(3042936) Bacteria identified in Isolate by Culture

1.45

0.39

2.6

1.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

197

0.76

0.37

2.7

2.4

—

(3022313) Gas panel - Capillary blood

1.46

0.36

6.3

5.5

—

(3003396) Base excess in Arterial blood by calculation

1.43

0.36

67.0

8.4

-0.4

1.1

mmol/l

—

(3035350) Ketones [Presence] in Urine by Test strip

290

1.24

0.35

3.5

2.9

0.0

estimate

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.39

0.35

1.7

3.4

4.7

4.9

pmol/l

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.39

0.35

1.7

1.5

1.2

1.1

g/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

595

1.31

0.35

4.5

4.0

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.36

0.34

2.0

2.3

—

21.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

547

0.80

0.34

3.0

2.9

1.1

1.2

mmol/l

0.24

513

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

129

1.30

0.33

2.9

2.2

87.1

219.9

u/l

1.50

129

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

118

0.73

0.30

1.4

1.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

180

1.23

0.27

1.9

1.7

104.9

96.1

pmol/l

0.36

(3015736) pH of Urine

239

1.20

0.26

3.5

2.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

289

1.18

0.24

5.1

4.3

0.0

estimate

—

(3019225) pH of Specimen

1.37

0.24

1.2

6.5

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.27

0.23

1.2

4.1

1.9

12.0

ug/l

—

(4094501)

0.00

0.21

0.0

1.3

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

9.8

—

0.6

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.0

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

0.8

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.6

—

17.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.0

—

(3044889) 12 lead EKG panel

352

1.16

0.20

2.7

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.17

0.19

1.2

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

294

1.15

0.19

3.6

3.0

0.0

estimate

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.73

0.17

1.4

1.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

253

0.87

0.16

1.9

2.1

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.17

0.10

6.2

5.7

23.9

24.0

mmol/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.16

0.09

1.2

2.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

136

1.13

0.09

3.7

2.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

186

1.10

0.08

1.5

1.4

2.4

2.1

g/l

0.26

107

(40768797) Stomach Pathology biopsy report

1.03

0.08

1.1

1.2

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.80

0.08

1.0

1.3

—

(36660697) Celiac disease serology panel - Serum

1.10

0.07

1.1

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

100

0.89

0.07

1.9

1.6

—

(3003694) ABO and Rh group [Type] in Blood

247

1.08

0.06

1.7

—

(3021960) Folate [Moles/volume] in Serum or Plasma

110

0.90

0.05

1.7

1.3

27.6

19.6

nmol/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

140

1.09

0.05

1.3

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

140

1.09

0.05

4.1

3.1

0.0

estimate

—

(3041096) Erythrocytes [Presence] in Urine by Automated

171

1.07

0.03

3.1

2.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

213

1.05

0.01

1.6

1.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

176

0.96

0.00

2.8

2.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

186

0.96

0.00

1.5

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

122

0.98

0.00

1.8

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

429

1.01

0.00

3.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

217

1.02

0.00

4.1

2.9

—

(40760892) CBC W Ordered Manual Differential panel - Blood

145

1.04

0.00

4.5

3.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

119

1.01

0.00

2.0

1.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

144

0.97

0.00

3.2

2.2

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

14.7

—

1041.7

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

24.2

—

1982.7

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(4281824)

0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.0

—

29.2

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

0.4

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

5.5

—

0.9

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

1.8

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.7

—

44.8

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

0.0

1.9

—

32.3

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.3

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.0

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.6

—

89.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.4

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.5

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.4

—

(40761536) Microorganisms panel - Urine sediment

1.00

0.00

3.0

3.1

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.1

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

0.0

1.9

—

51.5

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

78.1

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.0

1.9

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

1.6

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

3.6

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(4211845)

0.00

0.0

1.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.97

0.00

1.4

1.5

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(4062490)

0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3006462) Nitrate [Presence] in Urine

0.00

0.0

1.4

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.84

0.00

3.2

3.4

32.0

33.1

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

3.4

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

10.4

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

6.4

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

6.8

—

48.6

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

0.0

1.4

—

1.2

—

(40761511) CBC panel - Blood by Automated count

688

1.03

0.00

12.9

8.6

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

0.0

1.6

—

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_SYNDACTYLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_SYNDACTYLY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_SYNDACTYLY – Syndactyly

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Syndactyly

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints