muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
247 |
4. Check minimum number of eventsNone |
247 |
5. Include endpointsNone |
247 |
6. Filter based on genotype QC (FinnGen only) |
234 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M62
- Name in latin
- Ruptura musculi non traumatica
Similar endpoints
↥List of similar endpoints to
Other rupture of muscle
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1604 | 713 | 883 |
| Only index persons | 1502 | 672 | 830 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 53.09 | 53.57 | 52.63 |
| Only index persons | 52.22 | 52.43 | 52.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 234 | 125 | 109 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.05 |
| Median age at first event (years) | 53.04 | 50.08 | 56.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 247
- Matched controls
- 2470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.1
ICD-10 Finland
Other rupture of muscle (nontraumatic)
+∞
307.7
247
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.7
25.1
72
197
M79.6
ICD-10 Finland
Pain in limb
3.8
23.7
112
439
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
6.4
19.1
34
60
QBJ30
NOMESCO Finland
Correction of abdominal apron
68.3
17.0
19
*
N02BF01
ATC
gabapentin; oral
5.7
13.8
27
52
X59
ICD-10 Finland
Exposure to unspecified factor
3.3
13.3
60
218
M25.5
ICD-10 Finland
Pain in joint
2.9
13.0
85
382
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.9
12.4
23
42
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.6
11.1
28
67
M62.0
ICD-10 Finland
Diastasis of muscle
62.8
10.7
12
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
10.6
115
650
X58
ICD-10 Finland
Exposure to other specified factors
3.3
10.5
45
157
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
114.7
10.5
11
*
N02BE01
ATC
paracetamol; systemic, rectal
4.3
10.0
228
1814
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
4.4
10.0
26
64
N02AX02
ATC
tramadol; systemic, rectal
2.4
9.9
111
631
M79.1
ICD-10 Finland
Myalgia
3.3
9.8
41
141
N03AX12
ATC
[U] gabapentin; oral
3.1
9.6
45
166
UKC02
NOMESCO Finland
Cystoscopy
2.9
9.6
50
196
M70.6
ICD-10 Finland
Trochanteric bursitis
3.8
9.6
31
90
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
103.8
9.5
10
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
9.4
62
275
S18
ICPC
Laceration/cut
2.3
9.0
116
693
J01DB01
ATC
cefalexin; oral
3.0
9.0
210
1623
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
9.0
94
515
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.3
8.9
16
15
SPAT1263
SPAT
Sampling
2.3
8.9
109
638
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
8.8
117
706
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
17.1
8.6
13
8
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
8.4
34
114
G44.2
ICD-10 Finland
Tension-type headache
3.1
8.3
38
138
L03
ICPC
Low back symptom/complaint
2.4
8.1
67
329
N03AX16
ATC
[U] pregabalin
2.5
8.0
58
268
B01AB05
ATC
enoxaparin; parenteral
2.2
7.6
83
457
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
7.6
26
78
L14
ICPC
Leg/thigh symptom/complaint
3.7
7.5
24
69
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
82.5
7.5
8
*
L17
ICPC
Foot/toe symptom/complaint
2.3
7.4
70
363
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
7.4
100
599
M54.5
ICD-10 Finland
Low back pain
2.2
7.4
85
478
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
4.5
7.3
18
42
UJF32
NOMESCO Finland
Coloscopy
2.3
7.1
67
346
S76.3
ICD-10 Finland
Injury of muscle and tendon of the posterior muscle group at thigh level
10.5
7.1
13
13
R06.0
ICD-10 Finland
Dyspnoea
2.3
7.1
67
347
M02AA07
ATC
piroxicam; topical
2.1
6.8
87
507
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
6.8
100
614
M01AH05
ATC
etoricoxib; oral
2.0
6.8
150
1065
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
6.7
32
118
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.0
6.6
132
902
L08
ICPC
Shoulder symptom/complaint
2.5
6.6
48
221
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
6.5
44
196
B01AF02
ATC
apixaban; oral
2.9
6.5
31
115
NFL30
NOMESCO Finland
Transposition of muscle of hip or thigh
14.8
6.4
10
7
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.8
6.4
33
127
M76.6
ICD-10 Finland
Achilles tendinitis
5.8
6.4
17
31
SPAT1312
SPAT
General health counselling
2.1
6.3
81
471
A02BC02
ATC
pantoprazole; systemic
2.0
6.3
163
1211
H02AB06
ATC
prednisolone; systemic
2.0
6.3
114
750
Z50.1
ICD-10 Finland
Other physical therapy
4.0
6.2
18
48
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
6.2
171
1296
SXA20
NOMESCO Finland
Local application of medicine to mouth
3.8
6.2
19
53
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
6.2
56
284
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
6.1
72
405
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
814
2.34
9.73
23.4
12.6
1.18
1.26
inr
0.55
40
258
104
617
2.18
8.02
3.3
2.9
—
—
—
0
0
94
543
2.18
7.68
3.5
2.2
54.00
66.21
u/l
0.76
84
499
47
200
2.67
7.62
10.0
7.6
—
—
—
0
0
232
1970
3.93
7.01
20.7
13.6
139.68
139.73
mmol/l
0.12
225
1913
232
1979
3.84
6.77
20.3
13.7
3.95
3.97
mmol/l
0.52
226
1918
40
168
2.65
6.63
8.7
9.0
1.92
0.96
mmol/l
0.91
33
135
177
1342
2.13
6.61
4.2
3.5
10.58
11.28
mm/h
0.32
165
1242
56
278
2.31
6.49
1.1
1.2
15.80
30.94
iu/ml
1.11
16
88
184
1421
2.16
6.47
8.3
7.2
80.82
76.19
u/l
0.78
174
1338
183
1414
2.14
6.38
5.4
3.8
14.79
14.73
pmol/l
0.11
167
1281
125
846
1.97
6.34
3.1
2.4
—
—
—
0
0
103
654
1.99
6.27
4.2
3.6
25.04
48.05
ng/l
1.45
72
430
148
1065
1.97
6.24
6.6
4.4
6.76
6.64
mmol/l
0.26
141
981
210
1737
2.40
5.83
6.0
4.4
2.03
1.91
mu/l
0.44
193
1581
124
866
1.87
5.47
4.6
3.1
0.00
0.00
estimate
-0.00
25
185
51
261
2.20
5.44
1.2
1.2
1.40
8.69
u/ml
2.07
21
104
76
455
1.97
5.34
3.2
3.4
1329.62
1335.11
ng/l
0.00
66
382
224
1932
2.71
5.24
18.0
12.1
25.34
23.89
mg/l
0.22
193
1487
216
1833
2.42
5.23
15.1
11.4
84.56
82.85
ml/min/173m2
0.63
194
1512
119
829
1.84
5.22
8.5
6.7
1.21
1.21
mmol/l
0.02
102
699
104
699
1.84
5.09
4.6
3.2
—
—
—
0
0
75
459
1.91
4.88
4.3
3.5
0.00
0.00
estimate
-0.00
22
166
64
372
1.97
4.84
1.8
1.6
1.28
1.18
mg/l
0.12
54
291
39
188
2.28
4.78
10.8
8.3
104.33
104.90
mmol/l
0.36
39
188
24
93
2.75
4.63
11.7
11.7
92.08
94.18
%
0.43
24
93
108
751
1.78
4.61
6.2
4.7
35.92
36.02
g/l
0.06
101
706
122
879
1.77
4.61
4.6
3.1
0.00
0.00
estimate
-0.00
24
161
121
870
1.77
4.60
6.2
4.3
0.00
0.00
estimate
-0.00
24
174
108
755
1.76
4.50
7.0
5.8
1.21
1.21
mmol/l
0.08
95
692
78
495
1.84
4.49
2.3
2.0
176.90
186.70
u/l
0.10
73
461
239
2203
3.62
4.46
27.2
17.9
4.54
4.51
e12/l
0.28
234
2136
239
2201
3.65
4.45
27.6
18.0
40.50
40.47
%
0.02
227
2064
62
368
1.91
4.38
4.9
3.3
1.02
1.02
kg/l
0.06
11
51
33
155
2.30
4.29
4.9
3.3
6.08
5.64
kpa
1.23
33
150
33
155
2.30
4.29
4.7
3.3
2.27
1.73
mmol/l
0.32
26
120
127
943
1.71
4.18
7.4
6.4
10.82
11.37
umol/l
0.40
118
893
166
1332
1.75
4.08
3.5
2.9
48.25
45.88
u/l
0.17
153
1257
215
1871
2.15
4.07
4.7
4.1
6.01
5.89
mmol/l
0.46
201
1719
75
484
1.79
4.03
3.5
2.8
0.71
0.54
e6/l
0.17
66
364
100
703
1.71
3.97
2.0
2.2
74.15
74.34
nmol/l
0.02
92
642
29
138
2.25
3.67
3.1
2.5
73.15
64.52
ml/min/173m2
0.59
13
62
50
293
1.89
3.63
2.0
1.7
1322.12
1190.93
nmol/l
0.40
41
227
231
2091
2.62
3.62
12.2
9.2
27.77
26.23
u/l
0.61
226
2013
68
441
1.75
3.55
3.1
2.5
322.44
8232.62
umol/l
2.25
61
380
93
657
1.67
3.55
2.3
1.9
105.17
94.20
pmol/l
0.91
48
353
17
64
2.78
3.47
1.8
1.4
—
—
—
0
0
111
826
1.62
3.42
3.4
2.7
138.89
121.13
ug/l
0.29
104
771
23
102
2.38
3.41
2.3
3.3
3.02
1.22
mmol/l
1.18
18
80
202
1756
1.83
3.32
6.0
5.2
39.81
39.41
mmol/mol
0.26
189
1644
16
61
2.74
3.20
2.2
1.8
0.81
2.54
ug/l
0.54
16
49
77
530
1.66
3.20
3.4
3.6
14.81
10.96
mg/mmol
0.25
49
336
88
631
1.61
3.09
3.3
3.2
34.32
32.22
u/l
0.17
80
609
88
639
1.59
2.90
5.2
4.6
1.71
2.84
ug/l
1.02
80
574
64
430
1.66
2.89
2.5
2.0
—
—
—
0
0
47
290
1.77
2.88
3.0
2.4
1.25
1.03
e6/l
0.17
32
166
154
1273
1.56
2.83
3.7
3.2
—
—
—
0
0
26
132
2.08
2.83
9.4
8.3
9.23
9.58
mmol/l
0.08
26
125
216
1948
1.87
2.73
4.8
4.1
4.55
4.67
mmol/l
0.89
201
1820
33
186
1.89
2.69
2.2
1.7
—
—
—
0
0
193
1690
1.65
2.69
18.6
15.0
15.23
14.54
%
0.78
188
1664
21
100
2.20
2.67
1.3
1.4
—
—
—
0
0
218
1975
1.88
2.67
5.3
4.5
2.71
2.77
mmol/l
0.47
202
1831
14
55
2.64
2.66
1.6
1.6
—
—
—
0
0
33
188
1.87
2.61
2.2
1.8
—
—
—
0
0
44
274
1.74
2.61
2.3
1.8
—
—
—
0
0
35
204
1.83
2.58
5.1
4.4
30.86
31.37
%
0.09
28
131
214
1933
1.80
2.57
4.9
4.1
1.39
1.46
mmol/l
1.66
199
1795
10
31
3.32
2.55
1.2
1.1
—
—
—
0
0
207
1868
1.67
2.30
4.5
3.7
1.35
1.27
mmol/l
0.72
192
1727
9
29
3.18
2.25
1.2
1.4
—
—
—
0
0
48
319
1.63
2.24
4.7
3.5
1388.12
352.93
ng/l
0.37
34
247
42
272
1.66
2.16
3.3
2.6
7.25
2.03
e6/l
0.77
28
150
31
187
1.75
2.06
3.5
3.3
—
—
—
0
0
12
50
2.47
2.06
1.3
1.6
—
—
—
0
0
52
360
1.56
2.05
1.7
1.5
—
—
—
0
0
77
583
1.47
1.99
3.5
3.7
2.35
2.35
mmol/l
0.04
70
536
36
230
1.66
1.96
2.8
2.4
2.33
2.32
g/l
0.05
36
211
24
136
1.85
1.95
1.5
1.2
115.87
148.10
iu/ml
0.22
12
52
6
16
3.82
1.94
1.3
1.1
—
—
—
0
0
128
1069
1.41
1.92
10.3
9.6
4.04
4.03
e9/l
0.02
111
937
6
17
3.59
1.85
2.3
1.9
8.47
7.12
mmol/l
—
6
17
9
35
2.63
1.82
1.7
1.1
—
—
—
0
0
11
48
2.35
1.73
2.1
1.8
—
—
—
0
0
5
13
3.90
1.72
1.0
1.0
—
—
—
0
0
10
40
2.56
1.68
1.8
1.5
—
—
—
0
0
10
41
2.50
1.66
2.8
2.6
705.40
208.60
ug/l
—
10
41
52
377
1.48
1.65
1.3
1.2
6.09
0.83
u/ml
0.44
14
107
16
86
1.92
1.54
2.6
2.3
0.21
0.20
e6/l
0.02
16
81
67
517
1.41
1.53
4.7
4.2
22.52
20.44
%
0.51
31
228
15
79
1.96
1.53
3.8
2.2
0.61
0.60
%
0.01
15
79
11
51
2.21
1.53
1.0
1.8
9.82
10.65
g/l
0.31
11
44
5
16
3.17
1.44
1.2
1.8
—
—
—
0
0
15
81
1.91
1.43
3.8
2.2
1.47
1.04
%
0.84
15
81
51
383
1.42
1.35
2.0
1.7
422.93
12158476.14
pmol/l
0.50
43
329
8
34
2.40
1.30
1.1
1.1
—
—
—
0
0
52
396
1.40
1.28
1.7
1.5
24.43
19.42
nmol/l
1.22
47
341
11
56
2.01
1.24
1.3
1.1
—
—
—
0
0
11
56
2.01
1.24
1.3
1.1
—
—
—
0
0
11
57
1.97
1.19
1.0
1.8
7.94
6.95
g/l
0.79
11
51
11
57
1.97
1.19
1.0
1.8
3.90
3.34
g/l
0.84
11
51
11
57
1.97
1.19
1.0
1.8
—
—
—
0
0
8
39
2.09
1.16
1.4
1.2
—
—
—
0
0
5
20
2.53
1.15
1.2
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
51
2.00
1.13
5.7
2.0
0.19
0.34
u/ml
—
5
26
19
120
1.63
1.12
3.3
3.1
138.05
161.97
ng/l
0.23
19
103
15
89
1.73
1.10
1.6
1.3
—
—
—
0
0
11
59
1.90
1.09
2.4
3.0
—
—
—
0
0
5
22
2.30
1.04
4.6
2.2
108.40
106.18
mmol/l
—
5
22
20
131
1.57
1.03
3.5
3.7
1.22
1.23
mmol/l
0.27
14
115
26
183
1.47
0.98
5.5
4.6
228.50
250.63
u/l
0.37
26
173
7
36
1.97
0.98
3.6
1.8
—
—
—
0
0
47
370
1.33
0.95
3.6
2.8
0.68
0.72
ug/l
0.17
27
232
6
27
2.25
0.94
3.8
1.5
—
—
—
0
0
41
319
1.34
0.90
3.9
3.1
2.45
2.44
mmol/l
0.29
36
286
8
47
1.73
0.81
2.6
2.5
25.18
24.89
mmol/l
—
8
47
15
99
1.55
0.77
4.3
2.2
19.79
74.01
u/ml
1.35
15
94
18
125
1.47
0.75
2.4
1.3
—
—
—
0
0
5
25
2.02
0.73
1.0
1.1
—
—
—
0
0
9
57
1.60
0.72
1.1
1.2
—
—
—
0
0
14
93
1.54
0.71
1.0
1.1
—
—
—
0
0
7
41
1.73
0.70
1.0
1.9
0.00
0.00
g/l
—
7
36
5
28
1.80
0.66
1.8
1.6
—
—
—
0
0
8
52
1.56
0.60
1.0
1.8
3.69
2.62
g/l
—
8
46
6
35
1.73
0.58
1.2
1.2
—
—
—
0
0
6
36
1.68
0.57
1.8
1.6
—
—
—
0
0
6
36
1.68
0.57
1.0
1.9
0.00
0.00
g/l
—
6
31
59
511
1.20
0.56
1.6
1.7
1.24
1.39
mmol/l
0.89
44
435
6
40
1.51
0.52
1.3
1.0
—
—
—
0
0
7
45
1.57
0.49
1.6
1.5
—
—
—
0
0
7
49
1.44
0.46
1.0
2.3
0.00
2.59
g/l
—
7
41
16
121
1.34
0.45
1.8
1.6
—
—
—
0
0
7
51
1.38
0.44
1.0
1.5
—
—
—
0
0
30
251
1.22
0.41
1.6
1.9
1.31
1.44
%
0.73
25
223
5
33
1.53
0.41
2.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
8
60
1.34
0.40
1.1
1.6
—
—
—
0
0
5
34
1.48
0.40
1.2
1.1
—
—
—
0
0
5
35
1.44
0.39
1.6
1.1
—
—
—
0
0
5
35
1.44
0.39
1.6
1.1
—
—
—
0
0
12
89
1.37
0.38
3.1
1.6
—
—
—
0
0
9
67
1.36
0.38
2.2
1.6
—
—
—
0
0
5
36
1.40
0.38
1.2
1.6
—
—
—
0
0
6
44
1.37
0.34
1.0
1.8
36.30
39.02
g/l
—
6
38
18
217
0.82
0.30
1.4
1.7
—
—
—
0
0
24
204
1.20
0.30
1.7
1.8
—
—
—
0
0
5
71
0.70
0.26
1.4
1.5
—
—
—
0
0
5
71
0.70
0.26
1.4
1.5
—
—
—
0
0
5
71
0.70
0.26
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
9.09
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
4.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
5
68
0.73
0.17
4.0
1.6
—
—
—
0
0
8
68
1.18
0.17
1.4
1.5
—
—
—
0
0
35
322
1.10
0.16
1.7
1.5
—
—
—
0
0
6
76
0.78
0.16
1.5
1.6
—
—
—
0
0
6
77
0.77
0.16
1.7
1.4
279.23
315.74
mu/l
—
6
68
19
171
1.12
0.13
2.5
2.0
31.43
34.67
u/l
0.25
14
148
24
230
1.05
0.03
1.8
1.9
—
—
—
0
0
11
107
1.03
0.00
1.3
1.7
—
—
—
0
0
13
133
0.98
0.00
1.5
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
7
72
0.97
0.00
3.1
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
3.0
4.2
37.28
33.24
mg/l
—
5
38
0
9
0.00
-0.00
0.0
1.6
—
15.56
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
26.80
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
2.8
4.1
—
1.09
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
14.33
—
0
9
6
64
0.94
-0.00
2.2
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
3.0
4.2
55.60
73.79
mg/l
—
5
38
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_RUPTUREMUSC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RUPTUREMUSC | 1.322 [1.05, 1.67] | 0.019 |
| Birth year | 0.999 [0.99, 1.01] | 0.778 |
During the follow-up period (1.1.1998 — 31.12.2019), 96 out of 564 females with M13_RUPTUREMUSC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RUPTUREMUSC | 1.218 [1.01, 1.46] | 0.036 |
| Birth year | 0.992 [0.98, 1.0] | 0.09 |
During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 748 males with M13_RUPTUREMUSC died.
Mortality risk
Mortality risk for people of age
years, who have M13_RUPTUREMUSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.238% |
| 5 | 0.7% | 1.591% |
| 10 | 1.947% | 4.175% |
| 15 | 4.052% | 7.574% |
| 20 | 7.25% | 13.317% |
Relationships between endpoints
↥Index endpoint: M13_RUPTUREMUSC – Other rupture of muscle
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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