No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
178 |
4. Check minimum number of eventsNone |
178 |
5. Include endpointsNone |
178 |
6. Filter based on genotype QC (FinnGen only) |
178 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to Other specified acquired deformities of limbs based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1624 | 978 | 639 |
Only index persons | 1493 | 897 | 596 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.03 | 0.02 |
Only index persons | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 32.12 | 39.17 | 21.06 |
Only index persons | 31.42 | 38.34 | 21.00 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 178 | 119 | 59 |
Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
Median age at first event (years) | 39.75 | 39.35 | 40.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 158
- Matched controls
- 1579
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint M13_LIMBDEFORM and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_LIMBDEFORM | 1.57 [1.14, 2.17] | 0.006 |
Birth year | 0.994 [0.99, 1.0] | 0.203 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 621 females with M13_LIMBDEFORM died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have M13_LIMBDEFORM.N-year risk | Females | Males |
---|---|---|
1 | 0.187% | No data |
5 | 0.894% | No data |
10 | 2.358% | No data |
15 | 4.271% | No data |
20 | 7.636% | No data |
Relationships between endpoints
↥Index endpoint: M13_LIMBDEFORM – Other specified acquired deformities of limbs
GWS hits: -