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Mental and behavioural disorders associated with the puerperium

F5_MENTPUER

postpartum depression: An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F53
  • Hospital discharge: ICD-8 2944
  • Cause of death: ICD-10 F53
  • Cause of death: ICD-8 2944

2 out of 7 registries used, show all original rules.

440

4. Check minimum number of events

None

440

5. Include endpoints

None

440

6. Filter based on genotype QC (FinnGen only)

413

Control definitions (FinnGen only)

Control exclude
F5_BEHAVE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F50-F59
Name in latin
Perturbationes mentis et modi se gerendi puerperio adjunctae non alibi classificatae

Similar endpoints

List of similar endpoints to Mental and behavioural disorders associated with the puerperium based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 413 413 -
Unadjusted period prevalence (%) 0.15 0.15 -
Median age at first event (years) 30.44 30.44 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
440
Matched controls
4400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F53.0
ICD-10 Finland
Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
3333.6
209.9
186
*
F53.1
ICD-10 Finland
Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
143.9
130
*
N05AH04
ATC
quetiapine; oral
10.0
133.0
230
433
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
12.9
123.5
141
155
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
113.6
104
*
N05AH03
ATC
olanzapine; systemic
12.3
111.1
129
144
N05BA04
ATC
oxazepam; oral
7.0
93.5
241
649
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
14.8
90.1
87
72
29440
ICD-8 Finland
Psychosis associated with other physical conditions, Childbirth
+∞
83.0
77
*
F53.9
ICD-10 Finland
Puerperal mental disorder, unspecified
+∞
83.0
77
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
10.7
68.0
81
91
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.7
61.1
63
57
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.4
58.1
154
401
N05AX08
ATC
risperidone; systemic
8.2
57.3
85
125
N05AA02
ATC
levomepromazine; systemic
14.3
53.8
51
40
N05AB03
ATC
perphenazine; systemic, rectal
12.7
53.7
55
49
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
16.7
50.9
44
29
N06AB06
ATC
sertraline; oral
4.8
46.2
131
354
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
9.9
45.9
56
64
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
11.6
45.4
49
47
N05AX12
ATC
aripiprazole; systemic
7.1
45.4
75
123
N05AN01
ATC
lithium; oral
10.8
44.7
51
53
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
13.1
44.3
44
37
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.7
44.1
131
366
N05CD07
ATC
temazepam; oral
7.5
43.0
67
103
N03AG01
ATC
valproic acid; systemic, rectal
6.3
42.7
80
149
N06AX11
ATC
mirtazapine; oral
3.9
42.2
199
774
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.6
40.2
117
320
N06AB04
ATC
citalopram; systemic
4.0
39.6
152
510
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.5
37.4
81
172
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
6.1
35.2
67
126
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
11.8
32.4
34
31
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
6.1
32.2
61
114
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.7
30.3
78
191
N05AD01
ATC
haloperidol; systemic
11.4
29.9
32
30
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
7.8
29.8
43
60
N05BA06
ATC
lorazepam; systemic, sublingual
6.8
29.5
49
80
N05CF01
ATC
zopiclone; oral
3.3
29.4
156
629
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
7.7
29.4
43
61
P76
ICPC
Depressive disorder
4.5
28.4
79
205
N06AX16
ATC
venlafaxine; oral
3.5
26.9
118
421
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.9
26.7
92
279
O99.80
ICD-10 Finland
The fear of childbirth
3.6
24.7
96
315
N05AC02
ATC
thioridazine; oral
8.8
24.7
32
39
N06AB03
ATC
fluoxetine; oral
3.7
24.0
88
278
N06AB10
ATC
escitalopram; oral
2.9
23.6
155
693
ZY010
NOMESCO Finland
Hospital outpatient
4.7
22.9
58
139
F53.8
ICD-10 Finland
Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
22.1
21
*
P01
ICPC
Feeling anxious/nervous/tense
3.0
21.2
122
504
N05AF03
ATC
chlorprothixene; systemic
7.1
21.1
33
50
N03AX09
ATC
lamotrigine; oral
4.2
19.9
57
150
N06AB05
ATC
paroxetine; oral
4.4
19.8
54
137
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
6.7
19.6
32
51
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.9
19.5
31
48
Z2446
NOMESCO Finland
Social worker
4.3
19.2
54
140
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.2
18.9
41
86
P99
ICPC
Psychological disorders other
5.2
18.6
40
83
N04AA02
ATC
biperiden; systemic
7.8
18.4
26
35
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.9
18.2
34
62
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.7
18.0
119
524
N05AA01
ATC
chlorpromazine; systemic, rectal
14.5
18.0
30
22
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
5.9
17.7
33
60
P06
ICPC
Sleep disturbance
3.3
17.6
74
253
P29
ICPC
Psychological sympt/compl other
3.4
17.4
70
232
F31.8
ICD-10 Finland
Other bipolar affective disorders
6.4
17.1
29
48
SPAT1240
SPAT
Therapeutic discussion
2.9
16.9
91
359
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
7.6
16.7
24
33
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
18.8
16.7
25
14
ZY000
NOMESCO Finland
Hospital inpatient
15.1
16.5
27
19
N06AX03
ATC
mianserin; oral
6.1
16.4
29
50
N06AX12
ATC
bupropion; oral
3.3
15.8
66
224
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
15.7
15
*
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
4.9
15.4
35
76
P03
ICPC
Feeling depressed
2.8
14.7
85
346
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.6
14.6
36
84
N05CF02
ATC
zolpidem; oral
2.7
14.5
93
400
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.6
14.3
35
81
N06AA12
ATC
doxepin; systemic
5.4
14.3
29
57
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
15.1
14.2
23
16
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
11.0
13.9
26
25
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.7
13.6
86
366
N05BA01
ATC
diazepam; systemic, rectal
3.1
13.5
63
228
F32
ICD-10 Finland
Depressive episode
3.5
13.4
49
152
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
6.0
13.3
24
42
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.8
13.0
24
43
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.9
12.8
39
107
F20.9
ICD-10 Finland
Schizophrenia, unspecified
6.2
12.7
22
37
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.4
11.9
44
138
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
31.0
11.7
15
5
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.6
11.6
28
64
F31
ICD-10 Finland
Bipolar affective disorder
8.9
11.2
23
27
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.8
11.0
34
94
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
8.6
10.9
23
28
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.0
10.8
181
1144
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
8.3
10.7
23
29
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.5
10.7
21
40
F34.1
ICD-10 Finland
Dysthymia
4.0
10.7
31
82
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.0
10.7
49
175
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.0
10.6
240
1675
N05BA12
ATC
alprazolam; oral
2.9
10.5
54
205
R3110
NOMESCO Finland
Psychosocial training
4.4
10.5
27
65
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.2
10.4
105
548
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.7
10.3
33
94
2988A
ICD-9 Finland
Other nonorganic psychoses, Other and unspecified reactive psychosis
41.1
10.0
12
*
N06AX26
ATC
vortioxetine; oral
2.8
9.8
52
201
P74
ICPC
Anxiety disorder/anxiety state
3.1
9.7
42
145
P72
ICPC
Schizophrenia
5.3
9.4
19
37
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
5.3
9.4
19
37
N05BE01
ATC
buspirone; oral
4.9
9.1
20
42
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
16.0
9.1
14
9
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
9.0
237
1704
N06AX05
ATC
trazodone; oral
7.4
8.8
20
28
G02CB01
ATC
bromocriptine; systemic
4.3
8.8
23
56
N05AF05
ATC
zuclopenthixol; systemic
14.4
8.7
14
10
F33.3
ICD-10 Finland
Recurrent depressive disorder, current episode severe with psychotic symptoms
51.0
8.7
10
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
8.7
47
184
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
9.3
8.6
17
19
A06AD11
ATC
lactulose; oral
2.8
8.6
44
167
29999
ICD-8 Finland
Unspecified psychosis
28.1
8.5
11
*
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
20.5
8.5
12
6
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.1
8.4
18
23
SPAT1389
SPAT
Visit based on need for special support
3.8
8.4
26
72
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
11.0
8.4
15
14
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.1
8.3
23
59
Z2445
NOMESCO Finland
Psychologist
3.4
8.2
30
93
A10BA02
ATC
metformin; oral
2.1
8.2
88
467
IGP01
NOMESCO Finland
Psychiatric family contact
17.6
8.1
12
7
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
34.0
8.1
10
*
WZC30, ,
SPAT
3.5
8.1
28
84
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.0
8.0
95
523
N06AB08
ATC
fluvoxamine; oral
4.4
8.0
20
47
C07AA05
ATC
propranolol; systemic
2.0
8.0
112
654
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.6
8.0
19
43
W78
ICPC
Pregnancy
1.8
7.9
167
1112
ZYC01
NOMESCO Finland
Remote contact by phone
3.0
7.9
36
128
F99
ICD-10 Finland
Mental disorder, not otherwise specified
4.3
7.8
20
48
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.8
7.8
41
158
ZXY83
NOMESCO Finland
Social worker in multidisciplinary team
45.8
7.7
9
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.9
7.7
116
693
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.9
7.6
110
648
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
7.3
7.5
17
24
F39
ICD-10 Finland
Unspecified mood [affective] disorder
4.4
7.5
19
45
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.0
7.5
33
115
AA400
NOMESCO Finland
Electroconvulsive therapy
13.7
7.4
12
9
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
7.4
31
105
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.9
7.3
100
577
P98
ICPC
Psychosis NOS/other
9.6
7.3
14
15
N06AX21
ATC
duloxetine; oral
2.2
7.3
64
313
AA1AD
NOMESCO Finland
CT of head and brain
2.1
7.3
79
420
P73
ICPC
Affective psychosis
16.1
7.3
11
7
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.9
7.3
108
642
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
30.6
7.2
9
*
IER01
NOMESCO Finland
Psychoeducation, group
30.6
7.2
9
*
IHZ05, ,
SPAT
3.1
7.1
30
102
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
6.5
7.0
17
27
K59.09
ICD-10 Finland
Constipation, unspecified
3.4
6.9
25
77
F43.8
ICD-10 Finland
Other reactions to severe stress
3.4
6.9
25
77
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.7
6.9
162
1103
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.9
188
1334
188
Kela drug reimbursment
Psychosis requiring demanding treatment
8.5
6.9
14
17
IEY01
NOMESCO Finland
Psychoeducation, individual
11.2
6.8
12
11
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
7.4
6.8
15
21
F32.0
ICD-10 Finland
Mild depressive episode
3.8
6.7
20
54
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
6.6
6.7
16
25
T90
ICPC
Diabetes non-insulin dependent
2.2
6.7
62
310
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.0
6.5
73
393
F30.20
ICD-10 Finland
Mania with mood-congruent psychotic symptoms
70.8
6.4
7
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.8
6.4
19
51
F41
ICD-10 Finland
Other anxiety disorders
4.2
6.4
17
42
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.7
6.4
145
974
SPAT1254
SPAT
Administration of medicine
2.2
6.4
53
253
SPAT1097
SPAT
Recording of ECG
2.4
6.4
45
200
D11
ICPC
Diarrhoea
2.0
6.4
72
388
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
8.3
6.4
13
16
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.5
6.4
22
66
ZXY49
NOMESCO Finland
Other health care provider
18.3
6.3
9
5
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.9
6.2
94
559
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.2
149
1017
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
4.2
6.1
16
39
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.5
6.1
40
172
F28
ICD-10 Finland
Other nonorganic psychotic disorders
12.8
6.1
10
8
IGV01
NOMESCO Finland
Psychiatric network contact
12.8
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
115
553
2.46
14.19
1.7
1.5
435.65
74797171.22
pmol/l
1.59
104
492
172
984
2.23
14.17
2.5
2.9
2.34
2.35
mmol/l
0.56
160
891
206
1316
2.06
12.32
5.4
5.5
1.22
1.22
mmol/l
0.11
172
1123
323
2466
2.17
11.52
5.9
6.2
69.29
73.23
u/l
1.84
314
2313
245
1724
1.95
10.58
4.6
3.8
6.28
6.26
mmol/l
0.06
217
1518
81
388
2.33
9.81
1.7
1.5
1271.30
1121.07
nmol/l
0.62
67
306
109
593
2.11
9.65
1.5
1.4
20.98
21.57
nmol/l
0.15
99
523
168
1079
1.90
9.22
1.8
1.8
100.54
97.05
pmol/l
0.46
95
588
33
103
3.38
8.95
2.6
1.9
—
—
—
0
0
175
1159
1.85
8.59
5.3
4.7
1.22
1.22
mmol/l
0.24
161
1065
178
1208
1.80
7.91
2.9
3.0
28.18
27.24
u/l
0.17
169
1160
166
1114
1.79
7.59
1.8
1.9
—
—
—
0
0
389
3377
2.31
7.55
4.3
3.3
5.67
5.59
mmol/l
0.70
365
3165
318
2577
1.84
7.52
3.2
2.6
31.26
32.15
u/l
0.12
304
2461
155
1022
1.80
7.51
3.0
2.2
—
—
—
0
0
398
3505
2.42
7.18
12.6
8.9
139.25
139.53
mmol/l
1.76
391
3406
367
3135
2.03
7.13
6.2
4.4
14.00
14.28
pmol/l
1.62
353
2960
306
2472
1.78
7.07
5.3
3.8
7021.00
2217.30
e6/l
—
5
30
398
3513
2.39
7.00
12.9
8.9
3.88
3.88
mmol/l
0.12
389
3399
81
443
2.02
6.91
2.4
2.2
7664.43
4144.18
u/l
0.49
38
200
14
17
8.47
6.87
1.6
1.2
—
—
—
0
0
138
906
1.76
6.65
2.6
2.5
20.52
17.10
ng/l
0.16
60
389
14
19
7.57
6.46
3.5
2.5
49321.43
39110.53
ug/l
0.95
14
19
200
1463
1.67
6.44
2.2
2.2
72.88
74.38
nmol/l
0.36
187
1363
121
775
1.77
6.30
4.1
3.5
7.40
7.40
ph
0.12
26
136
39
164
2.51
6.24
3.6
2.2
—
—
—
0
0
138
931
1.70
5.93
3.1
2.3
54.15
55.00
u/l
0.12
123
866
93
561
1.83
5.87
2.9
2.3
508.89
520.86
mosm/kgh2o
0.15
80
477
160
1126
1.66
5.85
4.2
4.3
36.05
37.23
g/l
1.97
150
1052
410
3721
2.49
5.80
12.3
9.3
18.92
18.42
mg/l
0.12
330
2790
36
152
2.49
5.72
2.3
3.5
0.82
2.07
mmol/l
0.86
28
125
260
2076
1.62
5.62
3.1
2.7
—
—
—
0
0
233
1812
1.61
5.62
4.5
3.1
0.00
0.00
estimate
-0.00
54
393
118
773
1.72
5.60
4.2
3.0
—
—
—
0
0
93
569
1.80
5.59
4.0
3.5
—
—
—
0
0
232
1806
1.60
5.55
2.8
2.4
—
—
—
0
0
197
1479
1.60
5.45
3.9
2.8
6.04
5.94
ph
0.16
13
131
399
3601
2.16
5.38
7.3
5.0
1.57
2.06
mu/l
0.87
384
3421
57
302
2.02
5.28
3.5
3.7
4.56
4.70
pmol/l
0.49
48
271
60
326
1.97
5.18
2.1
2.1
383.21
378.64
nmol/l
0.06
52
305
39
179
2.29
5.18
5.6
3.7
1.24
1.23
mmol/l
0.54
30
153
309
2601
1.63
5.14
3.5
3.5
10.66
9.10
mm/h
1.76
295
2446
119
800
1.67
5.08
1.7
2.0
2.74
2.68
mg/l
0.12
98
688
48
243
2.09
5.02
2.4
1.6
—
—
—
0
0
229
1806
1.56
4.98
5.6
4.2
0.00
0.00
estimate
-0.00
53
378
231
1828
1.56
4.93
4.5
3.1
0.00
0.01
estimate
0.50
52
368
48
246
2.07
4.86
2.4
1.6
—
—
—
0
0
40
191
2.20
4.84
2.5
1.4
—
—
—
0
0
144
1026
1.60
4.84
1.8
1.7
—
—
—
0
0
303
2563
1.59
4.71
4.8
3.8
—
—
—
0
0
183
1389
1.54
4.63
1.9
1.8
—
—
—
0
0
47
244
2.04
4.60
2.2
1.6
—
—
—
0
0
253
2075
1.52
4.36
3.2
2.8
62.91
58.61
ug/l
0.26
239
1959
212
1676
1.51
4.36
6.2
5.7
—
—
—
0
0
154
1138
1.54
4.34
3.7
2.9
23.65
59.91
e6/l
1.53
103
711
159
1187
1.53
4.26
2.0
1.8
—
—
—
0
0
43
223
2.03
4.23
2.4
1.6
—
—
—
0
0
112
774
1.60
4.20
5.1
3.3
1.02
1.02
kg/l
0.14
16
116
73
452
1.74
4.17
1.9
2.3
2.42
2.41
mmol/l
0.20
65
384
201
1590
1.49
4.02
4.5
4.8
8.97
9.47
umol/l
0.55
191
1494
134
978
1.53
3.93
5.1
3.3
0.00
0.00
estimate
-0.00
50
378
47
259
1.91
3.91
3.2
3.4
—
—
—
0
0
198
1573
1.47
3.82
8.6
7.4
0.00
0.00
e9/l
0.67
159
1306
178
1387
1.48
3.78
2.4
2.0
—
—
—
0
0
51
293
1.84
3.74
2.5
2.1
36.50
28.74
u/l
0.56
46
245
22
91
2.49
3.70
6.4
4.6
23.54
24.35
mmol/l
0.50
22
91
44
242
1.91
3.68
2.3
1.6
—
—
—
0
0
219
1784
1.45
3.66
6.1
5.4
0.04
0.04
e9/l
0.21
191
1589
218
1776
1.45
3.63
5.9
5.4
0.54
0.52
e9/l
0.68
190
1589
385
3526
1.74
3.63
3.8
3.4
4.82
4.82
mmol/l
0.04
360
3363
47
266
1.86
3.61
6.0
5.8
1.10
1.03
mmol/l
0.75
42
245
384
3516
1.72
3.60
3.8
3.4
1.47
1.55
mmol/l
4.11
361
3343
245
2044
1.45
3.57
9.6
8.0
4.18
3.92
e9/l
1.16
217
1804
27
125
2.24
3.56
8.1
7.0
—
—
—
0
0
121
881
1.52
3.55
3.2
2.5
13.70
92.29
e6/l
1.48
99
657
89
606
1.59
3.51
3.0
2.2
7.59
9.43
e6/l
0.49
80
531
63
393
1.70
3.50
1.3
1.3
24.33
26.45
iu/l
0.19
54
339
89
610
1.58
3.41
1.7
1.5
—
—
—
0
0
225
1860
1.43
3.38
6.4
5.6
0.18
0.17
e9/l
0.20
201
1682
413
3882
2.04
3.31
9.8
7.9
22.29
23.45
u/l
1.06
405
3765
336
3003
1.50
3.26
5.3
4.1
37.39
37.62
mmol/mol
0.20
319
2849
205
1675
1.42
3.24
5.6
5.6
7.82
7.78
%
0.05
196
1578
116
852
1.49
3.23
5.5
6.1
—
—
—
0
0
12
34
3.60
3.22
1.2
3.4
27.08
33.76
umol/l
0.86
12
29
223
1853
1.41
3.19
6.2
5.3
2.06
2.03
e9/l
0.20
199
1696
25
118
2.19
3.16
1.8
3.1
5.03
5.16
kpa
0.21
25
111
39
218
1.87
3.13
5.6
5.2
104.97
104.92
mmol/l
0.03
39
218
37
204
1.89
3.10
1.7
2.4
0.24
0.22
g/l
0.69
32
196
385
3558
1.66
3.09
4.2
3.6
2.91
2.89
mmol/l
0.15
358
3373
57
359
1.68
3.07
1.9
1.5
—
—
—
0
0
18
75
2.46
3.01
1.6
2.6
1.56
1.40
%
0.17
18
75
367
3362
1.55
2.97
3.5
3.1
1.29
1.17
mmol/l
2.74
343
3179
202
1669
1.39
2.90
5.5
5.4
2.63
2.68
%
0.12
192
1567
87
616
1.51
2.87
2.3
2.1
—
—
—
0
0
105
779
1.46
2.75
3.3
2.5
0.19
0.28
e6/l
0.46
87
569
209
1748
1.37
2.74
5.4
5.4
30.18
29.71
%
0.29
199
1653
207
1736
1.36
2.63
5.7
5.2
56.45
56.59
%
0.07
196
1637
193
1601
1.37
2.63
5.6
5.4
0.65
0.68
%
0.31
183
1492
29
157
1.91
2.59
6.0
5.0
1.21
1.16
mmol/l
0.13
29
152
96
708
1.46
2.58
3.1
2.6
—
—
—
0
0
11
37
3.02
2.50
4.5
2.0
4.95
4.97
kpa
0.04
11
37
11
37
3.02
2.50
4.5
2.0
9.53
9.75
kpa
0.18
11
37
11
37
3.02
2.50
4.5
2.0
2.10
2.51
mmol/l
—
6
25
104
784
1.43
2.49
3.7
3.2
6.27
7.51
mmol/l
2.22
86
689
55
365
1.58
2.43
1.5
1.4
—
—
—
0
0
104
791
1.41
2.36
3.3
2.4
—
—
—
0
0
28
156
1.85
2.31
6.6
9.4
119.43
120.70
g/l
0.16
28
151
45
288
1.63
2.31
1.6
1.5
453.75
305.62
mu/l
0.78
40
254
136
1087
1.36
2.29
1.4
1.3
0.56
1.96
u/ml
1.81
50
296
25
135
1.90
2.27
1.4
2.4
4.31
5.15
umol/l
0.58
20
99
37
228
1.68
2.19
1.1
1.2
—
—
—
0
0
19
94
2.07
2.19
1.6
1.4
—
—
—
0
0
47
309
1.58
2.17
1.5
1.4
—
—
—
0
0
51
343
1.55
2.14
4.7
3.2
—
—
—
0
0
19
95
2.05
2.14
8.0
7.1
95.08
95.14
%
0.04
19
95
47
311
1.57
2.11
1.5
1.4
—
—
—
0
0
63
449
1.47
2.02
1.3
1.2
104.26
166.41
iu/ml
0.86
33
186
16
77
2.12
1.99
1.8
3.5
—
—
—
0
0
5
11
4.58
1.94
1.6
1.1
7.15
7.99
nmol/l
—
5
11
15
71
2.15
1.94
1.7
2.5
0.55
0.65
%
1.24
15
71
47
319
1.53
1.91
1.6
1.5
—
—
—
0
0
27
159
1.74
1.90
6.4
9.3
97.04
96.75
%
0.28
27
152
35
222
1.63
1.89
4.4
3.2
—
—
—
0
0
8
28
2.89
1.87
1.5
4.1
—
—
—
0
0
97
760
1.35
1.83
1.8
1.9
238.64
206.49
u/l
0.08
92
721
433
4232
2.46
1.82
20.4
14.2
39.22
39.71
%
1.26
412
4041
433
4231
2.47
1.82
20.6
14.4
271.80
267.67
e9/l
0.69
425
4155
55
392
1.46
1.78
2.9
2.2
2.63
2.48
g/l
0.85
46
360
32
202
1.63
1.77
2.6
3.9
68.36
70.67
ng/l
0.07
27
189
8
30
2.70
1.73
1.9
1.6
—
—
—
0
0
433
4238
2.36
1.70
20.6
14.4
7.00
6.72
e9/l
2.09
424
4149
433
4237
2.38
1.70
20.5
14.3
4.40
4.46
e12/l
2.54
422
4150
26
157
1.70
1.70
12.0
9.0
7.06
7.22
mmol/l
0.05
26
152
129
1066
1.30
1.67
7.0
6.6
1.03
1.06
inr
0.25
40
377
49
348
1.46
1.62
3.0
2.3
21.45
23.45
%
0.40
42
292
10
42
2.41
1.62
2.9
2.0
—
—
—
0
0
37
249
1.53
1.59
2.7
1.2
—
—
—
0
0
413
3984
1.60
1.57
13.0
9.0
—
—
—
0
0
22
130
1.73
1.56
2.4
2.4
—
—
—
0
0
49
353
1.44
1.52
2.0
2.5
4.61
5.26
umol/l
0.56
40
297
99
800
1.31
1.51
2.0
1.6
1.01
0.74
mg/l
0.78
75
583
5
16
3.15
1.44
1.2
2.1
156.40
140.31
nmol/l
—
5
16
29
190
1.56
1.41
6.8
8.2
0.55
1.10
mmol/l
0.25
24
138
42
577
0.70
1.41
1.3
1.3
—
—
—
0
0
51
383
1.38
1.27
1.5
1.4
—
—
—
0
0
108
903
1.26
1.26
1.4
1.4
2.22
2.05
g/l
0.76
69
568
16
93
1.75
1.23
4.9
12.3
—
—
—
0
0
8
37
2.18
1.22
1.4
2.3
5.44
6.80
mmol/l
—
8
37
10
50
2.02
1.17
1.7
2.6
21.62
137.78
ug/min
—
5
36
5
20
2.52
1.15
1.0
1.2
1208.00
1706.95
miu/ml
—
5
20
88
728
1.26
1.12
1.3
1.3
14.31
21.43
iu/ml
1.50
29
242
8
40
2.02
1.12
1.9
1.8
8.55
8.18
kpa
—
8
40
8
40
2.02
1.12
1.4
2.2
0.96
1.17
mmol/l
—
8
40
5
21
2.40
1.09
2.0
2.8
—
—
—
0
0
15
89
1.71
1.09
1.2
1.3
—
—
—
0
0
7
32
2.21
1.08
1.0
1.3
—
—
—
0
0
11
59
1.89
1.08
5.8
3.8
—
—
—
0
0
13
74
1.78
1.08
1.1
1.1
—
—
—
0
0
85
706
1.25
1.05
2.3
2.2
3950.28
4445.13
umol/l
0.05
74
638
27
189
1.46
1.02
7.2
8.2
5.23
5.10
kpa
0.26
27
177
27
189
1.46
1.02
7.2
8.2
12.45
13.65
kpa
0.93
27
178
355
3395
1.24
0.98
16.4
11.4
13.97
14.18
%
0.43
348
3343
5
23
2.19
0.98
1.2
2.3
—
—
—
0
0
81
678
1.24
0.94
4.7
4.0
17.08
8.47
mg/mmol
0.30
50
426
7
37
1.91
0.94
2.0
3.2
23.71
20.38
mu/l
—
7
37
9
52
1.75
0.93
2.6
3.3
—
—
—
0
0
86
727
1.23
0.92
1.3
1.3
6.06
8.31
u/ml
0.20
39
315
6
28
2.16
0.92
3.0
3.9
—
—
—
0
0
52
415
1.29
0.90
2.1
2.6
142.92
167.64
ng/l
0.07
23
205
125
1100
1.19
0.88
3.9
2.7
—
—
—
0
0
18
120
1.52
0.86
1.1
1.3
—
—
—
0
0
16
104
1.56
0.85
2.1
3.2
0.40
0.15
g/l
—
5
37
30
223
1.37
0.84
2.8
2.3
1.61
1.67
%
0.22
23
200
97
838
1.20
0.84
1.6
1.6
1.36
1.30
mmol/l
0.26
83
734
77
651
1.22
0.83
3.9
3.4
109.32
215.73
mg/l
0.34
45
422
47
375
1.28
0.83
1.1
1.2
—
—
—
0
0
16
105
1.54
0.83
5.1
10.2
25.92
25.13
mmol/l
0.23
16
97
29
381
0.74
0.79
2.1
1.7
—
—
—
0
0
79
674
1.21
0.78
1.4
1.5
—
—
—
0
0
67
562
1.23
0.78
1.9
2.4
72.91
88.28
ug/g
0.57
52
434
5
24
2.10
0.74
1.2
2.2
3.94
3.87
mmol/l
—
5
24
5
24
2.10
0.74
1.2
2.2
108.20
105.04
mmol/l
—
5
24
8
132
0.60
0.74
1.1
1.2
—
—
—
0
0
5
26
1.93
0.71
3.0
1.2
33.60
31.62
pg
—
5
26
10
61
1.65
0.69
1.6
1.9
282.90
193.60
ug/l
—
10
50
7
42
1.68
0.68
2.7
2.1
—
—
—
0
0
21
154
1.38
0.66
1.3
1.4
4.30
2.95
ug/l
0.38
21
139
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
50
420
1.21
0.60
2.5
2.3
4.74
4.90
e6/l
0.03
30
222
43
356
1.23
0.59
1.2
1.3
—
—
—
0
0
12
81
1.49
0.57
2.8
3.3
—
—
—
0
0
12
81
1.49
0.57
1.4
1.3
—
—
—
0
0
6
36
1.68
0.57
1.3
1.7
—
—
—
0
0
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
19
143
1.34
0.53
2.4
2.0
4.81
6.43
iu/l
—
8
56
10
66
1.53
0.53
1.3
1.4
—
—
—
0
0
9
132
0.68
0.52
1.3
1.3
—
—
—
0
0
45
381
1.20
0.51
1.9
1.9
—
—
—
0
0
67
588
1.16
0.51
1.3
1.4
1053.33
579.69
titre
—
9
130
11
75
1.48
0.51
1.2
2.0
—
—
—
0
0
9
65
1.39
0.51
1.2
1.4
—
—
—
0
0
14
101
1.40
0.50
16.1
6.4
—
—
—
0
0
21
163
1.30
0.49
1.7
1.6
—
—
—
0
0
29
354
0.81
0.49
1.2
1.3
—
—
—
0
0
11
76
1.46
0.48
1.5
1.3
69.24
126.00
u/ml
—
5
14
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
7
49
1.44
0.46
1.1
1.0
—
—
—
0
0
21
165
1.29
0.46
1.3
1.2
—
—
—
0
0
47
406
1.18
0.44
1.0
1.1
—
—
—
0
0
5
31
1.62
0.43
1.0
1.3
1.65
1.60
g/l
—
5
31
28
337
0.82
0.43
1.4
1.3
—
—
—
0
0
12
87
1.39
0.42
1.1
1.3
302.17
325.04
ug/g
—
6
42
19
149
1.29
0.42
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.8
—
—
—
0
0
5
35
1.43
0.39
1.2
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
2.6
—
50.45
—
0
11
0
19
0.00
0.39
0.0
1.3
—
132.09
—
0
19
11
80
1.38
0.38
1.3
1.1
5.67
6.92
u/ml
—
6
25
18
143
1.27
0.37
2.5
2.2
64.93
74.30
e9/l
—
10
100
6
41
1.47
0.36
1.2
1.2
—
—
—
0
0
19
154
1.24
0.34
1.6
1.6
—
—
—
0
0
11
144
0.76
0.34
1.4
1.5
65.73
63.23
pmol/l
0.07
11
139
12
92
1.31
0.32
1.2
1.5
326.25
360.55
mg/l
0.56
12
83
30
259
1.17
0.30
1.5
1.3
187.78
241.31
miu/ml
0.38
18
138
12
93
1.30
0.30
4.0
9.2
—
—
—
0
0
10
76
1.32
0.28
1.9
10.4
0.87
0.88
%
—
10
70
15
182
0.82
0.27
1.4
1.4
—
—
—
0
0
8
66
1.22
0.27
1.0
1.1
—
—
—
0
0
9
74
1.22
0.25
2.7
2.8
—
—
—
0
0
11
137
0.80
0.24
1.2
1.7
—
—
—
0
0
9
77
1.17
0.24
2.0
10.1
1.33
1.67
%
—
9
70
11
136
0.80
0.23
3.0
2.2
—
—
—
0
0
5
39
1.29
0.23
1.2
2.2
—
—
—
0
0
152
1579
0.94
0.21
1.7
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.01
—
0
12
0
14
0.00
0.20
0.0
2.9
—
0.19
—
0
14
12
144
0.83
0.20
1.3
1.5
1.12
1.17
g/l
0.27
12
135
6
52
1.16
0.19
1.5
1.2
—
—
—
0
0
152
1475
1.05
0.15
2.6
2.2
—
—
—
0
0
9
81
1.11
0.15
1.3
1.2
—
—
—
0
0
11
129
0.85
0.15
2.4
1.8
—
—
—
0
0
12
138
0.87
0.13
1.3
1.5
0.22
0.23
g/l
0.34
12
130
28
259
1.09
0.12
2.4
2.2
4.01
5.39
e9/l
0.58
20
233
11
95
1.16
0.11
1.0
1.1
—
—
—
0
0
11
95
1.16
0.11
1.0
1.1
—
—
—
0
0
27
250
1.09
0.11
1.1
1.1
—
240.00
—
0
5
26
241
1.08
0.10
6.4
4.5
0.56
0.88
%
—
9
69
28
261
1.08
0.10
1.0
1.2
—
—
—
0
0
5
44
1.14
0.10
2.6
16.3
12.20
10.51
mmol/l
—
5
39
5
45
1.11
0.10
2.6
15.9
107.80
105.37
mmol/l
—
5
40
6
58
1.03
0.08
1.2
1.0
—
—
—
0
0
8
77
1.04
0.07
4.0
10.8
0.99
1.08
mmol/l
—
8
62
49
472
1.04
0.07
1.2
1.2
—
—
—
0
0
9
88
1.02
0.07
1.7
2.3
—
—
—
0
0
13
119
1.10
0.06
1.0
1.1
—
—
—
0
0
25
237
1.06
0.06
3.5
2.4
—
—
—
0
0
29
278
1.05
0.04
1.2
1.2
—
19.21
—
0
17
24
229
1.05
0.04
6.8
4.6
0.00
0.14
%
—
7
57
23
220
1.05
0.03
6.9
4.7
0.00
0.18
%
—
7
50
23
223
1.03
0.01
5.7
4.3
0.37
0.68
%
—
8
58
25
256
0.98
0.00
1.3
1.4
—
—
—
0
0
23
225
1.02
0.00
1.0
1.1
—
—
—
0
0
342
3425
0.99
0.00
17.3
12.0
332.41
331.87
g/l
0.53
342
3393
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
7.00
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
289.40
—
0
5
8
81
0.99
-0.00
1.5
1.2
—
—
—
0
0
5
55
0.91
-0.00
1.4
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
7
72
0.97
-0.00
3.4
3.7
55.71
57.93
%
—
7
72
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
3.1
3.3
3.91
4.40
e9/l
—
7
70
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
12.8
3.4
1.00
0.85
nmol/l
—
6
48
5
49
1.02
-0.00
6.4
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_MENTPUER – Mental and behavioural disorders associated with the puerperium

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).