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Other drug-induced secondary parkinsonism

EFO Endpoint Browser PheWeb

OTHER_DRUGADVERS_SECONDA_PARKINSONI

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G21.1#

1 out of 7 registries used, show all original rules.

340

4. Check minimum number of events

None

340

5. Include endpoints

None

340

6. Filter based on genotype QC (FinnGen only)

333

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2777 1626 1117
Only index persons 2288 1355 933
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.04 0.05 0.04
Median age at first event (years)
Whole population 68.05 69.66 65.61
Only index persons 67.29 68.87 64.99

-FinnGen-

Key figures

All Female Male
Number of individuals 333 173 160
Unadjusted period prevalence (%) 0.07 0.06 0.07
Median age at first event (years) 63.96 64.91 62.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
340
Matched controls
3400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N05AH03
ATC
olanzapine; systemic
58.8
321.9
217
99
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
307.7
340
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
93.5
307.7
257
109
N04AA02
ATC
biperiden; systemic
70.8
212.9
120
26
N05AX08
ATC
risperidone; systemic
25.9
205.7
184
148
N05AA02
ATC
levomepromazine; systemic
33.3
193.8
140
70
N05AX12
ATC
aripiprazole; systemic
45.8
190.5
120
40
N05AH04
ATC
quetiapine; oral
20.9
185.1
238
341
N03AG01
ATC
valproic acid; systemic, rectal
26.7
180.5
145
92
N05AN01
ATC
lithium; oral
50.2
165.6
100
28
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
58.7
162.4
94
22
N05AB03
ATC
perphenazine; systemic, rectal
30.2
148.9
107
51
N05AF03
ATC
chlorprothixene; systemic
33.6
130.1
88
35
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
55.4
127.4
74
17
F20.9
ICD-10 Finland
Schizophrenia, unspecified
36.0
116.2
76
27
N05BA06
ATC
lorazepam; systemic, sublingual
15.1
112.0
117
114
F29
ICD-10 Finland
Unspecified nonorganic psychosis
22.7
104.1
82
47
R25.1
ICD-10 Finland
Tremor, unspecified
23.0
97.9
76
42
N05AC02
ATC
thioridazine; oral
29.5
85.5
59
24
P72
ICPC
Schizophrenia
22.7
84.3
65
35
N05AH02
ATC
clozapine; systemic
29.0
80.7
56
23
N05AD01
ATC
haloperidol; systemic
19.7
80.0
66
41
N05CD07
ATC
temazepam; oral
8.5
79.4
138
253
N05AA01
ATC
chlorpromazine; systemic, rectal
32.1
77.9
52
19
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
35.6
76.0
49
16
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
22.7
70.8
54
28
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
32.3
67.8
45
16
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
33.5
67.1
44
15
N05BA04
ATC
oxazepam; oral
6.3
63.8
193
590
G20
ICD-10 Finland
Parkinson disease
13.8
58.3
58
50
P99
ICPC
Psychological disorders other
16.5
57.4
51
36
N05BA01
ATC
diazepam; systemic, rectal
6.3
57.0
131
308
P29
ICPC
Psychological sympt/compl other
9.9
56.9
73
91
T36
ICD-10 Finland
Poisoning by systemic antibiotics
12.5
52.9
56
53
N03AX09
ATC
lamotrigine; oral
11.3
48.8
55
57
N06AB04
ATC
citalopram; systemic
5.1
47.6
156
488
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
17.7
45.0
38
24
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
64.8
43.8
50
9
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
64.8
43.8
50
9
N05BE01
ATC
buspirone; oral
11.3
43.8
49
50
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
79.4
43.3
48
7
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
13.6
42.7
42
35
SPAT1234
SPAT
Support of social functional capacity
9.5
41.4
53
65
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.0
40.8
71
124
N03AE01
ATC
clonazepam; systemic
7.4
39.2
63
101
SPAT1240
SPAT
Therapeutic discussion
6.4
38.4
73
139
IGY02
NOMESCO Finland
Psychiatric monitoring contact
13.8
36.3
35
28
N06AX03
ATC
mianserin; oral
7.8
35.0
53
79
C07AA05
ATC
propranolol; systemic
4.2
34.8
132
445
N05AF01
ATC
flupentixol; systemic
13.9
34.5
33
26
A28
ICPC
Limited function/disability NOS
4.4
34.2
117
365
L28
ICPC
Limited function/disability (L)
4.2
32.0
116
376
N06AG02
ATC
moclobemide; oral
7.6
31.9
49
74
A06AD11
ATC
lactulose; oral
4.3
31.7
105
318
N06AX16
ATC
venlafaxine; oral
4.4
31.2
99
290
F31
ICD-10 Finland
Bipolar affective disorder
34.6
31.1
40
13
U04
ICPC
Incontinence urine
6.9
30.3
51
85
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.8
29.7
79
201
SPAT1222
SPAT
Counselling/guidance promoting independent living
4.2
29.6
101
311
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
7.6
29.6
45
67
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
44.4
29.6
36
9
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
37.5
29.4
37
11
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
29.3
71
167
N06AB06
ATC
sertraline; oral
4.7
28.8
78
201
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
8.9
28.3
37
46
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
12.1
27.9
29
26
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
33.3
27.8
36
12
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
9.0
27.0
35
43
N05CF01
ATC
zopiclone; oral
3.4
27.0
179
844
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
26.4
112
398
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.9
26.2
51
98
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
7.3
25.7
40
61
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.2
25.7
30
32
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
5.3
25.6
57
124
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
25.0
137
570
ZY010
NOMESCO Finland
Hospital outpatient
6.7
24.8
42
70
SPAT1216
SPAT
Assessment of functional ability
3.7
24.1
95
320
SPAT1254
SPAT
Administration of medicine
3.9
24.1
87
276
R53
ICD-10 Finland
Malaise and fatigue
3.3
23.9
129
530
N05AF05
ATC
zuclopenthixol; systemic
36.4
23.8
30
9
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
8.2
23.8
33
44
188
Kela drug reimbursment
Psychosis requiring demanding treatment
50.7
23.7
28
6
F22.0
ICD-10 Finland
Delusional disorder
20.4
23.6
35
19
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.6
23.5
40
67
N06AA12
ATC
doxepin; systemic
5.2
22.8
51
111
N06AX11
ATC
mirtazapine; oral
3.1
22.8
171
845
K59.0
ICD-10 Finland
Constipation
5.3
22.5
49
104
F31.8
ICD-10 Finland
Other bipolar affective disorders
20.2
22.2
33
18
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.2
22.2
28
33
AA1AD
NOMESCO Finland
CT of head and brain
3.1
22.1
140
627
F25.20
ICD-10 Finland
Schizoaffective syndrome, mixed type with only concomitant bipolar and schizophrenic symptoms
85.9
22.0
24
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.3
21.3
46
97
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
223.1
20.8
21
*
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
44.8
20.7
25
6
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
51.4
20.4
24
5
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
38.4
20.1
25
7
G25.1
ICD-10 Finland
Drug-induced tremor
211.8
19.8
20
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.6
19.2
75
248
N05AL01
ATC
sulpiride; systemic
17.2
19.2
30
19
N06AB03
ATC
fluoxetine; oral
3.5
19.0
78
266
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
16.3
18.8
30
20
P98
ICPC
Psychosis NOS/other
46.8
18.5
22
5
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.9
18.4
44
101
N03AF01
ATC
carbamazepine; oral, rectal
4.7
18.3
46
110
F20.5
ICD-10 Finland
Residual schizophrenia
35.1
18.2
23
7
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
55.7
18.2
21
*
SPAT1307
SPAT
Psychosocial counselling and guidance
6.5
18.1
31
52
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.4
18.0
38
78
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
5.9
18.0
34
63
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.5
17.6
47
118
P76
ICPC
Depressive disorder
5.1
17.5
39
84
EBA30
NOMESCO Finland
Extraction of root of tooth
4.6
17.4
45
110
F03
ICD-10 Finland
Unspecified dementia
6.0
17.3
32
58
29580
ICD-8 Finland
Schizophrenia, Other
52.9
17.2
20
*
N07BB01
ATC
disulfiram; oral
5.3
17.0
36
74
G25.0
ICD-10 Finland
Essential tremor
7.1
16.8
26
39
AA400
NOMESCO Finland
Electroconvulsive therapy
42.4
16.5
20
5
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
23.4
15.7
22
10
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.6
15.6
58
184
N29
ICPC
Neurological sympt/complt other
15.8
15.6
25
17
N06AB05
ATC
paroxetine; oral
4.6
15.3
39
94
N05BA12
ATC
alprazolam; oral
3.4
15.2
61
204
A04
ICPC
Weakness/tiredness general
3.2
15.1
72
267
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.9
15.1
35
78
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.3
15.0
42
109
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
14.8
142
756
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
15.1
14.8
24
17
K08.3
ICD-10 Finland
Retained dental root
3.9
14.8
48
139
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.0
14.7
78
307
SPAT1301
SPAT
No procedures
2.5
14.5
138
731
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
14.4
57
188
SPAT1215
SPAT
Assessment of need for medical rehabilitation
5.7
14.4
28
53
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.9
14.0
44
124
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
55.8
13.9
16
*
N06AA06
ATC
trimipramine; systemic
5.8
13.8
26
48
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
5.8
13.8
26
48
ZYC01
NOMESCO Finland
Remote contact by phone
4.1
13.7
40
107
F21
ICD-10 Finland
Schizotypal disorder
35.7
13.6
17
5
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.9
13.6
25
45
N05AE04
ATC
ziprasidone; systemic
27.0
13.5
18
7
N05AX13
ATC
paliperidone; systemic
27.0
13.5
18
7
SPAT1229
SPAT
Assessment of need for aid
3.7
13.4
47
143
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
4.2
13.4
37
95
IGY99
NOMESCO Finland
Other psychiatric treatment contact
15.9
13.3
21
14
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
15.9
13.3
21
14
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.3
13.1
36
92
29999
ICD-8 Finland
Unspecified psychosis
23.7
13.0
18
8
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
23.7
13.0
18
8
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
13.0
55
189
29570
ICD-8 Finland
Schizophrenia, Schizo-affective type
52.1
12.9
15
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.4
12.9
51
168
F61.0
ICD-10 Finland
Mixed personality disorders
13.0
12.8
22
18
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.9
12.7
69
274
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
33.5
12.7
16
5
N30.0
ICD-10 Finland
Acute cystitis
2.9
12.7
71
287
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
18.2
12.7
19
11
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
12.6
126
674
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
21.0
12.6
18
9
R41.0
ICD-10 Finland
Disorientation, unspecified
5.2
12.4
26
53
F31.2
ICD-10 Finland
Bipolar affective disorder, current episode manic with psychotic symptoms
39.1
12.3
15
*
R32
ICD-10 Finland
Unspecified urinary incontinence
5.8
12.3
23
42
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.6
12.3
44
136
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.3
12.2
33
83
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.8
12.2
40
116
SPAT1167
SPAT
Insertion of urinary catheter
5.5
12.2
24
46
F20.0
ICD-10 Finland
Paranoid schizophrenia
27.9
12.2
16
6
R42
ICD-10 Finland
Dizziness and giddiness
2.4
12.1
105
525
N06AX12
ATC
bupropion; oral
4.4
12.1
32
79
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.9
12.1
66
262
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
12.1
118
622
N28
ICPC
Limited function/disability (N)
14.1
12.1
20
15
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
12.0
61
233
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
48.5
12.0
14
*
N06AA04
ATC
clomipramine; systemic
10.2
11.9
23
24
P01
ICPC
Feeling anxious/nervous/tense
3.4
11.9
45
144
F41.1
ICD-10 Finland
Generalized anxiety disorder
4.9
11.9
27
59
EBA00
NOMESCO Finland
Extraction of tooth
2.3
11.8
143
825
N05AD03
ATC
melperone; systemic
13.2
11.8
20
16
IGY02, ,
SPAT
23.9
11.7
16
7
A46
ICD-10 Finland
Erysipelas
2.7
11.6
72
306
G72.8
ICD-10 Finland
Other specified myopathies
10.1
11.4
22
23
F05.9
ICD-10 Finland
Delirium, unspecified
10.1
11.4
22
23
N30.9
ICD-10 Finland
Cystitis, unspecified
3.8
11.4
36
102
T90
ICPC
Diabetes non-insulin dependent
2.3
11.3
114
607
P03
ICPC
Feeling depressed
3.6
11.2
39
118
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
10.6
11.2
21
21
I95.1
ICD-10 Finland
Orthostatic hypotension
4.9
11.1
25
54
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.9
11.1
58
225
29599
ICD-8 Finland
Schizophrenia, Unspecified type
44.9
11.0
13
*
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
11.1
10.9
20
19
N06AX05
ATC
trazodone; oral
5.2
10.9
23
47
R60.0
ICD-10 Finland
Localized oedema
2.8
10.9
63
258
C03CA01
ATC
furosemide; systemic
2.2
10.8
135
783
P28
ICPC
Limited function/disability (P)
29.1
10.8
14
5
N05CD02
ATC
nitrazepam; oral
5.5
10.7
21
40
N06AA09
ATC
amitriptyline; systemic
3.0
10.7
53
199
F25.01
ICD-10 Finland
Schizoaffective syndrome, manic type with prolonged schizophrenic than bipolar symptoms
62.0
10.7
12
*
N06AB08
ATC
fluvoxamine; oral
5.1
10.6
23
48
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.6
10.5
22
27
Z2446
NOMESCO Finland
Social worker
3.5
10.5
38
118
97010
ICD-8 Finland
Adverse effect of psychotherapeutics, Tranquillisers
113.4
10.5
11
*
G21.0
ICD-10 Finland
Malignant neuroleptic syndrome
113.4
10.5
11
*
F25
ICD-10 Finland
Schizoaffective disorders
+∞
10.5
10
*
N05AE05
ATC
lurasidone; oral
+∞
10.5
10
*
F25.2
ICD-10 Finland
Schizoaffective disorder, mixed type
+∞
10.5
10
*
F25.21
ICD-10 Finland
Schizoaffective syndrome, mixed type with prolonged schizophrenic than bipolar symptoms
+∞
10.5
10
*
F20.08
ICD-10 Finland
Paranoid schizophrenia other definite
+∞
10.5
10
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.7
10.4
25
57
SPAT1172
SPAT
Guidance concerning hydration
9.2
10.4
21
24
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
10.0
10.4
20
21
2957A
ICD-9 Finland
Schizophrenic psychoses, Schizo-affective type
33.7
10.4
13
*
SPAT1252
SPAT
Overall medication plan or its review
3.5
10.4
38
119
SPAT1241
SPAT
Extensive assessment of psychosocial situation
19.5
10.4
15
8
F34.1
ICD-10 Finland
Dysthymia
4.2
10.3
28
71
K59.09
ICD-10 Finland
Constipation, unspecified
3.3
10.2
41
136
30041
ICD-8 Finland
Neuroses, Depressiva
11.8
10.2
18
16
N17
ICPC
Vertigo/dizziness
2.8
10.1
56
224
SPAT1243
SPAT
Psychiatric/psychological examination
8.0
10.1
22
29
29540
ICD-8 Finland
Acute schizophrenia episode
41.4
10.0
12
*
A10BA02
ATC
metformin; oral
2.2
10.0
126
729
SPAT1360
SPAT
Extensive global examination
3.4
9.9
37
117
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
26.9
9.9
13
5
N05AC01
ATC
periciazine; systemic
26.9
9.9
13
5
L89
ICD-10 Finland
Decubitus ulcer and pressure area
9.5
9.7
19
21
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
18.2
9.5
14
8
SPAT1053
SPAT
Memory test
2.5
9.5
65
289
F30.20
ICD-10 Finland
Mania with mood-congruent psychotic symptoms
102.8
9.5
10
*
H03AA01
ATC
levothyroxine sodium; systemic
2.2
9.4
97
516
2962E
ICD-9 Finland
Affective psychoses, Major depressive disorder, single episode[PSYCH.BIPOLARIS MANICA,VAIKEA-ASTE,PSYKOOT PIIRTEIT]
+∞
9.4
9
*
F20
ICD-10 Finland
Schizophrenia
14.2
9.3
15
11
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.0
9.2
44
162
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
5.0
9.2
20
42
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
9.2
63
280
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
11.9
9.2
16
14
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
9.1
74
355
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
37.8
9.1
11
*
Z2445
NOMESCO Finland
Psychologist
4.4
9.1
23
55
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
19.2
9.0
13
7
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.4
8.9
33
104
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
4.3
8.9
23
56
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
8.8
117
685
N06AX22
ATC
agomelatine; oral
8.0
8.8
19
25
N99
ICPC
Neurological disease other
14.5
8.8
14
10
TKC20
NOMESCO Finland
Catheterisation of bladder
3.1
8.8
38
132
D12
ICPC
Constipation
3.8
8.7
27
75
SPAT1310
SPAT
Counselling related to known health issue
2.0
8.7
127
769
ZY000
NOMESCO Finland
Hospital inpatient
12.0
8.7
15
13
P20
ICPC
Memory disturbance
2.5
8.6
62
281
G25.2
ICD-10 Finland
Other specified forms of tremor
16.8
8.6
13
8
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
8.6
114
666
S72.0
ICD-10 Finland
Fracture of neck of femur
4.1
8.6
24
62
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.7
8.6
28
81
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.7
8.6
28
81
U07
ICPC
Urine symptom/complaint other
3.1
8.5
38
134
P73
ICPC
Affective psychosis
28.3
8.5
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
8.5
64
296
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
5.1
8.5
18
37
G21.8
ICD-10 Finland
Other secondary parkinsonism
92.3
8.5
9
*
IEV99
NOMESCO Finland
Other psychiatric network intervention
92.3
8.5
9
*
N06AB10
ATC
escitalopram; oral
2.3
8.4
75
374
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.6
8.4
28
82
A29
ICPC
General symptom/complaint other
2.5
8.4
61
278
F23.91
ICD-10 Finland
Acute and transient psychosis, unspecified without acute stress factor
+∞
8.4
8
*
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
+∞
8.4
8
*
S01.0
ICD-10 Finland
Open wound of scalp
3.0
8.3
38
136
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.4
8.3
30
93
P27
ICPC
Fear of mental disorder
15.0
8.3
13
9
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.2
8.2
81
422
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
12.1
8.1
14
12
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
17.7
8.1
12
7
F23.90
ICD-10 Finland
Acute and transient psychosis, unspecified without acute stress factor
34.2
8.1
10
*
F25.1
ICD-10 Finland
Schizoaffective disorder, depressive type
34.2
8.1
10
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
8.1
24
65
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.8
8.0
44
174
30188
ICD-8 Finland
Personality disorders, Alia definita
13.5
7.9
13
10
N87
ICPC
Parkinsonism
8.8
7.9
16
19
E86
ICD-10 Finland
Volume depletion
7.2
7.9
18
26
F60.9
ICD-10 Finland
Personality disorder, unspecified
11.2
7.9
14
13
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
11.2
7.9
14
13
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
7.8
106
621
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
15.5
7.8
12
8
2959C
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,KROONINEN]
46.1
7.7
9
*
IEY02
NOMESCO Finland
Intensified psychiatric outpatient care, Assertive Community Treatment (ACT)
46.1
7.7
9
*
IER01
NOMESCO Finland
Psychoeducation, group
46.1
7.7
9
*
OAB43, ,
SPAT
0.2
7.7
8
364
29530
ICD-8 Finland
Schizophrenia, Paranoid type
18.9
7.6
11
6
G04BD08
ATC
solifenacin; oral
2.9
7.6
37
137
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
9.2
7.6
15
17
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
25.7
7.6
10
*
G04BD12
ATC
mirabegron; oral
2.4
7.6
57
263
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.6
7.5
18
41
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.9
7.5
22
59
R50.9
ICD-10 Finland
Fever, unspecified
2.3
7.5
65
320
IGV01
NOMESCO Finland
Psychiatric network contact
13.8
7.4
12
9
IHZ05, ,
SPAT
6.5
7.3
18
29
F23.9
ICD-10 Finland
Acute and transient psychotic disorder, unspecified
+∞
7.3
7
*
F33.31
ICD-10 Finland
Recurrent depression, severe episode of somatic syndrome
+∞
7.3
7
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.1
7.3
20
51
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
7.2
48
209
K03.66
ICD-10 Finland
Tooth plaque
3.0
7.2
33
118
L17
ICPC
Foot/toe symptom/complaint
1.9
7.2
112
685
J01EA01
ATC
trimethoprim; systemic
2.0
7.2
99
581
SPAT1139
SPAT
Nutrition survey
4.2
7.2
19
47
F61
ICD-10 Finland
Mixed and other personality disorders
20.5
7.2
10
5
SPAT1101
SPAT
Orthostatic test
3.8
7.1
22
61
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
12.4
7.1
12
10
K02.1
ICD-10 Finland
Caries of dentine
1.9
7.1
199
1468
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
7.1
37
143
A01
ICPC
Pain general/multiple sites
2.6
7.0
43
181
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
6.9
6.9
16
24
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
40.9
6.8
8
*
F30.9
ICD-10 Finland
Manic episode, unspecified
40.9
6.8
8
*
29830
ICD-8 Finland
Other psychoses, Acute paranoid reaction
17.1
6.8
10
6
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
6.8
114
715
D01AC02
ATC
miconazole; topical
2.7
6.7
38
153
A69
ICPC
General and Unspecified, Other reason for encounter NEC
5.7
6.7
18
33
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
23.0
6.7
9
*
F25.0
ICD-10 Finland
Schizoaffective disorder, manic type
23.0
6.7
9
*
N06AC02, ,
ATC
23.0
6.7
9
*
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.1
6.7
17
29
SPAT1081
SPAT
Cardiorespiratory global assessment
3.0
6.7
29
101
P74
ICPC
Anxiety disorder/anxiety state
4.0
6.6
19
50
A03
ICPC
Fever
2.3
6.6
55
265
S97
ICPC
Chronic ulcer skin
2.8
6.6
35
136
N06AX26
ATC
vortioxetine; oral
3.1
6.6
28
96
F41.09
ICD-10 Finland
UNS Panic Syndrome
6.4
6.5
16
26
2959A
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,TARKEMMIN MÄÄRITTELEMÄT]
71.1
6.4
7
*
F28
ICD-10 Finland
Other nonorganic psychotic disorders
71.1
6.4
7
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
71.1
6.4
7
*
ZXY03
NOMESCO Finland
Occupational therapist
71.1
6.4
7
*
29510
ICD-8 Finland
Schizophrenia, Hebephrenic type
71.1
6.4
7
*
2961C
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,KESKIVAIKEA]
14.7
6.4
10
7
D11
ICPC
Diarrhoea
2.4
6.4
47
214
W19
ICD-10 Finland
Unspecified fall
2.5
6.4
41
176
IGY99, ,
SPAT
18.4
6.3
9
5
IHZ07, ,
SPAT
18.4
6.3
9
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
6.3
104
646
F51.0
ICD-10 Finland
Nonorganic insomnia
2.2
6.3
54
264
IER04, ,
SPAT
+∞
6.3
6
*
29630
ICD-8 Finland
Affective psychoses, Manic-depressive psychosis, circular type
+∞
6.3
6
*
F23.29
ICD-10 Finland
Acute schizophrenia-like psychosis UNS
+∞
6.3
6
*
N06AX21
ATC
duloxetine; oral
2.3
6.3
49
230
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
27.2
6.3
8
*
F23.99
ICD-10 Finland
Acute and transient psychosis, unspecified UNS
27.2
6.3
8
*
30310
ICD-8 Finland
Alcoholism, Habitual excessive drinking
27.2
6.3
8
*
2953E
ICD-9 Finland
Schizophrenic psychoses, Paranoid type[PARANOIDISTYYPPINEN SKITSOFRENIA,KROONINEN AKUUTTI]
27.2
6.3
8
*
R41.3
ICD-10 Finland
Other amnesia
4.1
6.2
17
43
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
6.2
67
358
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
7.9
6.2
13
17
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
8.8
6.1
12
14
F41.3
ICD-10 Finland
Other mixed anxiety disorders
8.8
6.1
12
14
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
6.1
56
282
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
6.0
32
702
F32.1
ICD-10 Finland
Moderate depressive episode
3.3
6.0
23
74

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
153
541
4.32
38.38
2.4
1.7
1263.86
1224.97
nmol/l
0.18
116
407
38
13
32.70
29.21
10.9
15.8
1019.87
1580.15
nmol/l
1.53
38
13
227
1337
3.10
21.62
6.3
6.1
1.22
1.21
mmol/l
1.15
210
1212
145
675
3.00
21.17
1.8
1.5
18.48
20.85
nmol/l
1.25
122
560
182
964
2.91
20.84
3.2
3.5
2.36
2.35
mmol/l
0.39
148
837
207
1176
2.94
20.75
2.9
2.0
95.41
95.72
pmol/l
0.03
118
580
171
881
2.89
20.56
5.0
3.2
—
—
—
0
0
234
1435
3.02
20.08
7.3
7.1
1.23
1.22
mmol/l
1.80
203
1230
160
809
2.85
19.73
5.3
4.3
—
—
—
0
0
167
876
2.78
19.01
3.5
2.1
699.64
266.18
u/l
0.57
157
817
266
1846
3.03
16.47
8.4
4.5
1428.33
1864.69
e6/l
—
6
32
205
1264
2.57
15.85
4.4
4.7
33.93
35.50
g/l
3.16
192
1194
129
658
2.55
14.72
2.4
2.1
3.12
3.31
mg/l
0.35
107
563
119
590
2.56
14.36
1.9
1.8
470.83
451.42
pmol/l
0.30
95
482
163
935
2.43
14.31
2.7
2.5
48.16
61.26
u/l
1.79
146
856
237
1615
2.54
14.04
15.7
9.4
4.23
4.09
e9/l
0.49
209
1416
211
1378
2.40
13.53
7.6
5.6
0.63
0.58
e9/l
1.87
182
1189
214
1408
2.40
13.46
7.9
5.6
1.84
1.92
e9/l
0.32
188
1247
211
1381
2.39
13.42
7.6
5.6
0.04
0.04
e9/l
0.90
181
1193
281
2102
2.94
13.38
6.0
3.8
14.82
14.89
pmol/l
0.16
252
1872
215
1422
2.39
13.30
8.8
5.8
0.18
0.19
e9/l
0.43
185
1250
183
1166
2.23
11.88
2.7
2.2
74.99
78.64
nmol/l
0.87
164
1024
238
1711
2.30
11.19
7.3
5.0
6.88
6.79
mmol/l
0.27
228
1604
195
1300
2.17
10.99
7.9
6.1
—
—
—
0
0
194
1291
2.17
10.98
7.1
5.7
2.47
2.85
%
1.49
183
1207
197
1323
2.16
10.84
7.4
5.9
26.58
27.32
%
0.39
188
1242
50
181
3.07
10.78
5.2
3.5
7.41
7.42
ph
—
8
20
194
1298
2.15
10.74
7.5
6.1
8.70
8.68
%
0.02
183
1217
257
1933
2.35
10.47
7.3
4.4
—
—
—
0
0
188
1251
2.12
10.46
7.3
5.7
0.61
0.69
%
1.26
177
1167
194
1310
2.12
10.34
7.1
5.7
58.48
57.36
%
0.65
185
1233
283
2230
2.60
10.23
8.0
7.8
80.97
80.44
u/l
0.08
272
2081
145
884
2.12
10.07
3.7
3.8
7.40
7.40
ph
0.01
30
156
55
226
2.71
9.38
2.7
3.8
92.30
80.98
ng/l
0.26
40
202
19
24
8.32
8.98
2.3
1.2
—
—
—
0
0
75
369
2.32
8.71
3.5
5.5
0.99
1.02
mmol/l
0.37
66
341
16
17
9.81
8.37
4.6
2.0
—
—
—
0
0
145
939
1.95
8.08
3.5
3.1
6.14
7.42
mmol/l
2.95
118
777
48
202
2.60
7.77
4.9
7.1
—
—
—
0
0
87
477
2.11
7.67
1.9
3.6
0.84
0.82
mmol/l
0.78
76
448
70
356
2.22
7.44
4.8
9.1
2.57
1.22
mmol/l
1.12
56
295
120
746
1.94
7.42
6.9
4.1
0.00
0.01
estimate
0.50
36
229
209
1558
1.89
7.31
4.9
6.6
8.95
11.49
umol/l
5.48
199
1468
36
135
2.86
7.26
4.6
3.6
—
—
—
0
0
60
289
2.31
7.25
6.1
4.1
—
—
—
0
0
51
984
0.43
7.21
3.5
3.2
—
—
—
0
0
54
249
2.39
7.20
3.8
3.5
—
—
—
0
0
138
910
1.87
7.05
3.7
3.2
518.19
120.06
mg/l
0.39
93
589
77
417
2.09
6.95
2.0
2.2
2.31
2.35
g/l
0.24
61
384
54
254
2.34
6.88
1.6
1.9
412.15
368.41
nmol/l
0.67
46
234
236
1849
1.90
6.85
5.3
3.2
47.18
56.52
u/l
0.86
218
1704
158
1097
1.82
6.77
4.8
3.6
5.83
5.87
ph
—
6
80
20
54
3.87
6.74
2.6
1.2
—
—
—
0
0
20
55
3.80
6.57
2.5
1.2
—
—
—
0
0
54
260
2.28
6.51
3.1
2.5
4.89
7.58
ug/l
0.88
41
237
299
2566
2.37
6.50
8.4
4.7
1.83
2.43
mu/l
0.67
279
2302
64
331
2.15
6.48
1.7
2.5
1.87
1.82
%
0.12
55
304
20
57
3.67
6.26
2.6
1.2
—
—
—
0
0
20
57
3.67
6.26
2.5
1.2
—
—
—
0
0
164
1175
1.76
6.14
6.8
3.7
278.02
36.50
ng/l
0.46
141
866
141
968
1.78
6.11
4.2
3.8
7.80
8.18
mg/mmol
0.04
93
603
9
6
15.35
5.93
2.0
1.2
—
—
—
0
0
184
1380
1.73
5.72
6.1
3.8
0.00
0.00
estimate
0.50
38
256
19
56
3.53
5.67
1.1
1.2
—
—
—
0
0
93
574
1.85
5.66
3.6
2.9
404.63
552.80
mosm/kgh2o
9.75
72
487
88
538
1.86
5.50
3.1
3.1
2.47
2.45
mmol/l
0.92
78
472
78
459
1.91
5.48
2.2
2.2
10.40
12.90
umol/l
2.90
67
424
8
5
16.33
5.43
1.8
1.4
15.03
20.66
umol/l
—
8
5
133
924
1.72
5.37
3.5
3.2
1218.27
1123.94
ng/l
0.15
114
779
40
187
2.29
5.15
5.9
2.7
10.17
9.22
e9/l
0.05
19
147
16
45
3.68
5.11
2.4
1.2
—
—
—
0
0
17
50
3.53
5.09
1.2
1.3
—
—
—
0
0
46
230
2.16
5.05
1.9
2.8
66.63
66.77
g/l
0.05
31
208
93
598
1.76
4.87
3.5
2.4
5.65
4.55
e6/l
0.45
83
537
8
7
11.66
4.81
2.5
2.9
37975.00
39685.71
ug/l
—
8
7
32
140
2.42
4.78
2.2
3.3
3.88
4.50
pmol/l
2.79
23
119
28
115
2.56
4.77
2.1
2.1
0.70
4.46
ug/l
0.92
21
108
114
781
1.69
4.74
4.3
2.9
—
—
—
0
0
17
53
3.32
4.68
7.8
2.5
—
—
—
0
0
251
2110
1.72
4.63
4.4
4.1
13.93
12.37
mm/h
0.76
230
1927
182
1413
1.62
4.57
16.2
12.8
1.26
1.25
inr
0.06
53
403
28
119
2.47
4.46
4.8
4.5
—
—
—
0
0
93
613
1.71
4.41
6.8
4.2
1.02
1.02
kg/l
0.71
17
82
46
243
2.03
4.38
1.8
2.7
72.10
71.90
e9/l
0.01
40
191
18
61
3.06
4.35
1.2
1.7
—
—
—
0
0
23
90
2.67
4.31
4.6
12.5
1.35
1.22
mmol/l
0.32
23
81
178
1388
1.59
4.29
7.4
5.0
0.00
0.00
estimate
-0.00
36
232
67
405
1.81
4.27
2.2
2.2
18.47
21.90
%
1.57
49
344
180
1410
1.59
4.24
6.2
3.8
0.00
0.00
estimate
-0.00
35
226
49
268
1.97
4.23
3.9
3.6
3.47
2.16
mmol/l
1.32
40
221
40
203
2.10
4.23
2.0
2.3
—
—
—
0
0
124
890
1.62
4.21
4.4
3.1
31.93
130.64
e6/l
0.73
99
676
17
57
3.09
4.18
2.8
1.2
—
—
—
0
0
138
1022
1.59
4.09
5.1
3.7
117.77
104.58
e6/l
0.11
104
729
11
22
5.13
4.04
1.1
1.2
—
—
—
0
0
15
49
3.16
3.85
6.5
2.0
14.34
16.54
%
—
10
22
45
247
1.95
3.85
4.1
8.3
—
—
—
0
0
95
663
1.60
3.53
5.3
3.7
—
—
—
0
0
112
813
1.56
3.52
4.4
3.0
0.28
0.48
e6/l
1.03
88
605
13
37
3.61
3.44
2.5
1.2
—
—
—
0
0
306
2798
1.94
3.38
26.7
14.8
29.23
23.54
mg/l
2.05
272
2232
141
1087
1.51
3.33
3.1
2.6
144.27
142.94
ug/l
0.02
127
990
22
97
2.36
3.27
2.0
3.6
45.80
121.12
mg/l
0.59
16
78
22
97
2.36
3.27
2.0
3.6
42.20
30.36
mg/l
0.39
16
80
9
19
4.83
3.26
1.0
1.1
—
—
—
0
0
13
44
3.03
3.17
2.8
2.5
—
—
—
0
0
25
119
2.19
3.13
4.8
9.7
1.89
1.62
%
0.63
25
112
79
553
1.56
2.85
4.6
4.0
80.83
256.33
ng/l
1.19
66
460
19
84
2.34
2.83
2.3
3.2
—
—
—
0
0
87
626
1.52
2.77
2.0
1.7
0.91
1.31
mg/l
1.73
68
499
45
275
1.73
2.76
2.0
2.4
30.21
32.28
u/l
0.22
38
230
7
14
5.08
2.74
3.3
1.4
—
—
—
0
0
97
716
1.50
2.74
3.0
3.8
85.88
90.89
%
0.94
92
702
17
73
2.40
2.69
6.9
2.2
25.52
25.06
mmol/l
0.12
17
73
0
70
0.00
2.62
0.0
1.6
—
—
—
0
0
16
68
2.42
2.60
5.6
14.2
105.63
105.25
mmol/l
0.11
16
63
16
68
2.42
2.60
5.6
14.2
10.81
11.17
mmol/l
0.12
16
63
29
159
1.90
2.53
5.1
12.7
—
—
—
0
0
23
117
2.04
2.47
5.0
9.9
1.02
0.92
%
0.63
23
111
314
2950
1.84
2.38
32.4
17.5
139.93
139.74
mmol/l
0.59
308
2867
7
17
4.18
2.37
1.3
1.1
2.26
1.85
mmol/l
—
7
17
37
226
1.71
2.29
3.0
2.8
4.73
4.30
kpa
0.59
37
220
94
712
1.44
2.29
10.0
7.0
—
—
—
0
0
293
2711
1.58
2.26
8.7
6.1
41.02
40.41
mmol/mol
0.45
265
2510
300
2792
1.63
2.25
7.2
4.8
6.26
6.04
mmol/l
1.97
275
2537
6
164
0.35
2.21
1.2
1.3
—
—
—
0
0
314
2960
1.80
2.20
32.0
17.5
4.04
3.99
mmol/l
3.42
308
2873
6
14
4.34
2.16
1.0
1.1
169.17
136.21
nmol/l
—
6
14
9
31
2.95
2.08
1.6
2.5
—
—
—
0
0
8
27
3.01
1.95
1.0
1.5
—
—
—
0
0
11
46
2.44
1.87
8.8
2.1
—
—
—
0
0
15
74
2.07
1.78
2.3
4.0
—
—
—
0
0
15
278
0.52
1.74
1.3
1.4
—
—
—
0
0
30
188
1.65
1.73
1.1
1.2
—
—
—
0
0
13
62
2.14
1.67
7.8
2.2
7.93
7.92
kpa
0.01
13
62
10
41
2.48
1.65
1.4
1.6
—
—
—
0
0
16
85
1.93
1.57
1.3
1.4
293.86
278.66
ug/g
—
7
46
34
226
1.56
1.56
4.0
3.1
175.55
170.26
ng/l
0.03
29
203
44
310
1.48
1.55
2.1
2.2
99.29
131.87
ug/g
0.39
31
256
5
15
3.37
1.53
2.6
1.5
11.40
8.19
mmol/l
—
5
15
17
95
1.83
1.46
1.3
2.2
38.21
37.83
g/l
—
8
83
9
42
2.17
1.34
5.0
2.8
51.11
58.55
%
—
9
42
47
348
1.41
1.30
1.8
1.6
—
—
—
0
0
225
2060
1.27
1.30
5.0
4.0
—
—
—
0
0
8
35
2.32
1.27
1.5
2.1
—
—
—
0
0
30
204
1.52
1.27
4.7
4.4
0.00
0.17
%
—
10
63
63
492
1.34
1.27
3.7
2.9
1.47
2.40
e6/l
0.89
36
273
31
213
1.50
1.26
5.1
4.2
0.46
0.53
%
0.14
13
77
5
19
2.65
1.22
1.2
1.6
—
—
—
0
0
145
1271
1.25
1.19
14.4
9.1
0.00
0.00
e9/l
0.37
109
1033
6
26
2.33
1.19
1.0
1.2
—
—
—
0
0
53
408
1.35
1.17
1.2
1.2
—
—
—
0
0
56
708
0.75
1.17
1.3
1.3
—
—
—
0
0
33
234
1.45
1.16
9.5
3.4
—
—
—
0
0
5
20
2.52
1.15
2.2
1.6
10.50
11.83
%
—
5
20
5
113
0.43
1.15
1.2
1.1
—
—
—
0
0
45
339
1.38
1.14
1.8
2.9
5.44
8.66
umol/l
1.77
39
300
7
30
2.36
1.13
2.6
2.3
—
—
—
0
0
31
221
1.44
1.07
5.0
4.3
0.00
0.15
%
2.66
11
80
10
52
1.95
1.07
2.7
3.0
—
—
—
0
0
43
326
1.37
1.06
1.6
1.6
—
—
—
0
0
107
919
1.24
1.04
6.1
3.9
—
—
—
0
0
33
240
1.42
1.03
4.8
4.1
0.92
0.92
%
0.00
13
99
10
175
0.56
1.01
6.4
3.7
—
—
—
0
0
106
912
1.24
1.01
2.1
2.4
—
—
—
0
0
31
224
1.42
1.01
1.6
1.4
—
—
—
0
0
7
35
2.02
1.00
1.1
2.1
34.57
33.09
pg
—
7
35
5
23
2.19
0.98
1.0
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
1.2
—
—
—
0
0
55
441
1.29
0.94
1.8
2.0
—
—
—
0
0
9
52
1.75
0.93
1.7
1.7
58.22
60.97
%
—
9
52
148
1328
1.20
0.92
2.3
2.6
—
—
—
0
0
8
44
1.84
0.86
1.1
1.4
—
—
—
0
0
302
2915
1.32
0.86
27.6
14.0
—
—
—
0
0
284
2722
1.26
0.84
4.8
4.3
1.56
1.31
mmol/l
3.71
247
2463
18
121
1.51
0.84
2.6
3.2
—
—
—
0
0
70
587
1.24
0.84
1.3
1.2
1.11
1.48
u/ml
0.37
11
149
45
360
1.29
0.80
1.2
1.3
—
—
—
0
0
22
157
1.43
0.79
2.8
2.4
—
—
—
0
0
7
40
1.77
0.71
5.4
2.3
4.17
4.94
e9/l
—
7
40
5
26
1.94
0.71
3.2
2.4
508.60
478.00
ml
—
5
13
292
2826
1.24
0.66
5.3
4.8
4.21
4.66
mmol/l
12.14
258
2589
309
3010
1.29
0.65
15.4
11.0
25.91
26.81
u/l
0.24
302
2882
20
147
1.38
0.63
1.3
1.3
—
—
—
0
0
85
749
1.18
0.63
6.7
3.4
—
—
—
0
0
38
463
0.80
0.62
1.3
1.3
31.54
12.06
u/ml
—
10
179
13
88
1.50
0.61
2.4
2.4
5.38
81.73
ug/min
—
8
47
28
353
0.77
0.60
1.5
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
1.04
—
0
20
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
18
133
1.37
0.56
1.7
1.8
—
—
—
0
0
9
60
1.51
0.54
8.3
1.8
113.00
134.70
g/l
—
9
40
6
38
1.59
0.54
1.5
4.1
—
—
—
0
0
6
38
1.59
0.54
2.8
3.0
—
—
—
0
0
7
107
0.65
0.49
1.1
1.6
—
—
—
0
0
13
93
1.41
0.49
22.6
11.3
—
—
—
0
0
10
68
1.48
0.47
1.7
3.0
—
—
—
0
0
41
478
0.84
0.46
1.3
1.3
23.87
37.72
iu/ml
—
10
150
10
69
1.46
0.44
1.5
1.2
—
—
—
0
0
5
31
1.62
0.43
1.4
1.5
75.40
58.39
%
—
5
23
6
92
0.65
0.43
11.3
4.9
—
—
—
0
0
315
3097
1.23
0.41
43.7
21.8
39.26
40.36
%
2.07
285
2899
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
14.66
—
0
9
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
1.46
—
0
8
0
16
0.00
0.41
0.0
1.5
—
1.63
—
0
16
44
382
1.17
0.41
1.6
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
1.90
—
0
10
0
17
0.00
0.41
0.0
1.0
—
4.56
—
0
5
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
19
151
1.27
0.39
1.1
1.2
22.67
126.97
iu/ml
—
7
63
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
5
36
1.39
0.38
1.4
1.1
—
—
—
0
0
6
90
0.66
0.33
3.2
2.4
—
—
—
0
0
314
3095
1.19
0.33
43.7
21.7
243.72
246.00
e9/l
0.26
309
3008
11
83
1.34
0.32
1.1
1.2
—
3.10
—
0
6
7
52
1.35
0.31
1.4
1.4
—
—
—
0
0
7
53
1.33
0.31
1.1
1.5
—
—
—
0
0
110
1034
1.09
0.30
4.1
4.6
1.88
2.32
ug/l
0.54
91
921
18
217
0.82
0.30
2.6
2.1
11.90
14.10
nmol/l
0.86
13
194
314
3098
1.18
0.30
43.8
21.7
4.36
4.50
e12/l
5.09
309
2999
314
3098
1.18
0.30
44.2
21.7
7.11
6.63
e9/l
4.27
308
3002
55
602
0.90
0.28
2.9
2.9
0.68
0.76
ug/l
0.35
43
397
14
172
0.81
0.28
1.4
1.4
—
—
—
0
0
286
2809
1.11
0.27
5.4
4.7
1.34
1.47
mmol/l
5.76
249
2554
5
73
0.68
0.26
1.0
1.2
—
46.00
—
0
5
5
73
0.68
0.26
1.4
1.3
—
—
—
0
0
293
2887
1.11
0.23
6.1
5.4
2.36
2.76
mmol/l
12.51
259
2628
25
283
0.87
0.22
1.8
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
3.85
—
0
5
0
12
0.00
0.21
0.0
2.3
—
55.08
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
4.91
—
0
7
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
31
279
1.12
0.20
1.6
1.5
—
—
—
0
0
73
774
0.93
0.20
3.2
2.7
8507.96
7582.44
umol/l
0.04
56
660
14
165
0.84
0.20
1.4
1.2
—
—
—
0
0
36
330
1.10
0.17
2.4
4.7
2.84
27.66
ug/l
1.04
28
280
24
267
0.89
0.17
1.3
1.5
—
—
—
0
0
7
63
1.11
0.17
1.1
1.2
—
—
—
0
0
20
225
0.88
0.17
2.0
2.3
9.69
10.15
g/l
0.24
15
205
14
120
1.17
0.16
1.0
1.7
—
—
—
0
0
57
538
1.07
0.15
1.4
1.4
2.57
2.60
g/l
0.04
23
321
11
129
0.85
0.15
1.3
1.2
—
—
—
0
0
23
210
1.10
0.12
6.8
2.7
—
—
—
0
0
112
1142
0.97
0.07
2.1
2.1
—
—
—
0
0
9
87
1.04
0.07
1.2
1.2
—
—
—
0
0
78
794
0.98
0.04
1.6
1.7
1.59
1.40
mmol/l
1.01
67
653
26
270
0.96
0.03
1.6
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
6.56
—
0
7
0
7
0.00
0.00
0.0
3.7
—
7864.86
—
0
7
0
7
0.00
0.00
0.0
2.0
—
1.21
—
0
7
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.99
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
63
0.95
-0.00
2.2
2.0
3.29
4.66
mmol/24h
—
6
54

Mortality – FinRegistry

↥

Association

Association between endpoint OTHER_DRUGADVERS_SECONDA_PARKINSONI and mortality.

Females

Parameter HR [95% CI] p-value
OTHER_DRUGADVERS_SECONDA_PARKINSONI 2.378 [2.09, 2.71] < 0.001
Birth year 0.994 [0.99, 1.0] 0.129

During the follow-up period (1.1.1998 — 31.12.2019), 653 out of 1405 females with OTHER_DRUGADVERS_SECONDA_PARKINSONI died.

Males

Parameter HR [95% CI] p-value
OTHER_DRUGADVERS_SECONDA_PARKINSONI 2.878 [2.39, 3.47] < 0.001
Birth year 0.987 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 476 out of 955 males with OTHER_DRUGADVERS_SECONDA_PARKINSONI died.

Mortality risk

Mortality risk for people of age

years, who have OTHER_DRUGADVERS_SECONDA_PARKINSONI.

N-year risk Females Males
1 0.252% 0.529%
5 1.105% 3.197%
10 3.376% 7.776%
15 6.141% 14.768%
20 10.724% 23.847%

Relationships between endpoints

↥

Index endpoint: OTHER_DRUGADVERS_SECONDA_PARKINSONI – Other drug-induced secondary parkinsonism

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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